4F59A

Triple mutant src sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
108
structure length
108
Chain Sequence
DSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETVKGAYALSVSDFDNAKGLNVKHYLIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Superbinder SH2 Domains Act as Antagonists of Cell Signaling.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Proto-oncogene tyrosine-protein kinase Src
total genus 29
structure length 108
sequence length 108
ec nomenclature ec 2.7.10.2: Non-specific protein-tyrosine kinase.
pdb deposition date 2012-05-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4f59A00
1KA6A 2H8HA 3QWXX 3VS2A 2HMHA 2HDVA 1X27A 5HKWA 4X6SA 1SHBA 3KFJA 3VS3A 2HDXA 4XZ0A 1RQQC 1AOTF 3VRPA 2BBUA 5AULA 3OP0A 5HKYA 3BUWB 1A08A 2RSYA 3BUNB 2LQNA 2RORA 1PICA 4LUDA 2OZOA 3UYOA 3EACA 1SHAA 3CWGA 4JE4A 1D1ZA 3CXLA 1O43A 1KSWA 1BMBA 1Z3KA 4E93A 4E68A 5D0JA 5DC9A 1BFIA 3HCKA 1JYQA 1F1WA 2C9WA 3N7YA 1IS0A 4L1BB 4XZ1A 1YVLA 2GE9A 2MRJA 1NZLA 5DC0B 1LUIA 2PNBA 1B47A 1JYRA 5BO4A 3PLFB 5IBMA 2C0IA 2AUGA 2C0TA 1XA6A 4NWFA 1OO4A 2B3OA 3VGOA 1QADA 2L3TA 3IMDA 1CJ1A 2MK2A 1A81A 2IUIA 1O4DA 2EOBA 4GWFA 1BG1A 3GQIB 3MAZA 2K7AB 4A4BA 3BUXB 3IMJA 1TCEA 1A1CA 3NHNA 4D8KA 1SPSA 3C7IA 4U1PA 2CIAA 3S8NA 2PLEA 1D4TA 2VIFA 2SHPA 1CWEA 1A1BA 1FBVA 4A4CA 2HCKA 4EIHA 1AYCA 5CDWA 1O49A 3VRNA 2ETZA 2H5KA 1A09A 1FHSA 1GHUA 1RPYA 1O42A 2AOAA 2DM0A 2EL8A 1LUKA 2ECDA 2LNXA 1O4EA 2DCRA 3GXXA 2KNOA 1O4BA 3CBLA 2Y3AB 1R1PA 1Y57A 1UUSA 4P9ZA 4F5BA 2DLYA 1JYUA 2PNAA 5IBSA 2MC1A 1YVHA 1FU6A 1O4JA 5GJIA 3VRRA 3VS7A 1AYDA 1O4HA 1IJRA 1BLJA 2LNWA 3VRZA 1M61A 3VS1A 3VS4A 2RVFA 4K44A 1QCFA 2SRCA 3VRYA 1BHHA 1A07A 5DC4A 1CSYA 2C0OA 1FU5A 2Y1NA 1NZVA 4NWGA 1O4CA 3PJPA 1LCKA 3UF4A 2MRKA 3BUOB 4ROJA 5EELA 1JU5A 2IUGA 3TL0A 3VS6A 3WA4A 2CBLA 2IUHA 2FO0A 3MXYA 1AB2A 1QG1E 2FCIA 3OVEA 1HCTB 4OHIA 1O4RA 2EKXA 1RJAA 5EHPA 4K11A 1A1AA 3VS0A 3OV1A 3HIZB 4H34A 3VROA 2Y1MA 4K45A 1BM2A 4F5AA 1O48A 2EO3A 3ZNIA 3T04A 2YSXA 3VS5A 1SKJA 1A1EA 2CI9A 2JYQA 5EG3B 3MXCA 3OB2B 4WWQA 4LUEA 4OHLA 1O4AA 2IZVA 4JGHA 1O4LA 1BFJA 1AD5A 1CWDL 4JEGA 2DX0A 1KA7A 2ABLA 1AOUF 1R1QA 4DGPA 1SHDA 2DLZA 1O4MA 1WQUA 3VRQA 1K9AA 1OPLA 5KAZA 1OPKA 1P13A 2L6KA 3PFVA 3S8LA 3PSJA 2XP1A 2CR4A 1O4PA 4M4ZA 3K2MA 4DGXA 4TZIA 1CSZA 1R1SA 3M7FA 2PTKA 4EY0A 2EO6A 5GJHA 1MILA 2OQ1A 1LUMA 3OB1B 3N84A 1O4OA 1NRVA 1SPRA 1O4GA 4FL2A 1BHHB 3PS5A 2EU0A 3IN8A 5EEQA 5EHRA 1O4FA 1Y1UA 1UURA 3PQZA 1D4WA 4QSYA 1LCJA 2K79B 1ZFPE 4FBNA 2LCTA 2RMXA 1BLKA 3EAZA 1O45A 2GSBA 1HCSB 2YU7A 4K2RA 1G83A 1F2FA 1O46A 1FBZA 4OHDA 5DF6A 4FL3A 1FMKA 2PLDA 4H1OA 2HUWA 2DVJA 1H9OA 3S9KA 1O47A 2EYZA 3S8OA 1LKKA 3HHMB 5HKZA 1FYRA 4U17A 3TKZA 3N8MA 3CD3A 3QWYA 2MQIA 2EYYA 3IN7A 1O4KA 1JWOA 2CRHA 3US4A 5I6VA 4GPLB 1LUNA 1O44A 1BF5A 2QMSA 5J3XA 2H46E 4GL9E 2CS0A 4OHHA 4F59A 1AYAA 1O41A 2AOBA 1LKLA 2L4KA 1GRIA 1I3ZA 1X0NA 1O4QA 1BKLA 1X6CA 1BKMA 3BUMB 1O4NA 1AYBA 4P9VA 3GXWA 1OO3A 2KK6A 3PSKA 1M27A 2LQWA 1O4IA 3BKBA 1MW4A 1BHFA 5AXIA 2CI8A 4OHEA 2EYVA 1TZEE 1KC2A
chains in the Genus database with same CATH superfamily
1KA6A 2H8HA 3QWXX 3VS2A 2HMHA 2HDVA 1X27A 5HKWA 4X6SA 1SHBA 3KFJA 3VS3A 2HDXA 4XZ0A 1RQQC 1AOTF 3VRPA 2BBUA 5AULA 3OP0A 5HKYA 3BUWB 1A08A 2KGYA 2RSYA 2LRAA 3BUNB 2LQNA 2RORA 1PICA 4LUDA 2OZOA 3UYOA 3EACA 1SHAA 3CWGA 4JE4A 1D1ZA 3CXLA 1O43A 1KSWA 1BMBA 1Z3KA 4E93A 4E68A 5D0JA 5DC9A 1BFIA 3HCKA 1JYQA 1F1WA 2C9WA 3N7YA 1IS0A 4L1BB 4XZ1A 1YVLA 2GE9A 2MRJA 1NZLA 5DC0B 1LUIA 2PNBA 1B47A 1JYRA 5BO4A 3PLFB 5IBMA 2C0IA 2AUGA 2C0TA 1XA6A 4NWFA 1OO4A 2B3OA 3VGOA 1QADA 2L3TA 3IMDA 1CJ1A 2MK2A 1A81A 2IUIA 1O4DA 2EOBA 4GWFA 1BG1A 3GQIB 3MAZA 2K7AB 4A4BA 3BUXB 3IMJA 1TCEA 1A1CA 3NHNA 4D8KA 1SPSA 3C7IA 4U1PA 2CIAA 3S8NA 2PLEA 1D4TA 2VIFA 2SHPA 1CWEA 1A1BA 1FBVA 4A4CA 2HCKA 4EIHA 1AYCA 5CDWA 1O49A 3VRNA 2ETZA 2H5KA 1A09A 1FHSA 1GHUA 1RPYA 1O42A 2AOAA 2DM0A 2EL8A 1LUKA 2ECDA 2LNXA 1O4EA 2DCRA 3GXXA 2KNOA 1O4BA 3CBLA 2Y3AB 1R1PA 1Y57A 1UUSA 4P9ZA 4F5BA 2DLYA 1JYUA 2PNAA 5IBSA 2MC1A 1YVHA 1FU6A 1O4JA 5GJIA 3VRRA 3VS7A 1AYDA 1O4HA 1IJRA 1BLJA 2LNWA 3VRZA 1M61A 3VS1A 3VS4A 2RVFA 4K44A 1QCFA 2SRCA 3VRYA 1BHHA 1A07A 5DC4A 1CSYA 2C0OA 1FU5A 2Y1NA 1NZVA 4NWGA 1O4CA 3PJPA 1LCKA 3UF4A 2MRKA 3BUOB 4ROJA 5EELA 1JU5A 2IUGA 3TL0A 3VS6A 3WA4A 2CBLA 2IUHA 2FO0A 3MXYA 1AB2A 1QG1E 2FCIA 3OVEA 1HCTB 4OHIA 1O4RA 2EKXA 1RJAA 5EHPA 4K11A 1A1AA 3VS0A 3OV1A 3HIZB 4H34A 3VROA 2Y1MA 4K45A 1BM2A 4F5AA 1O48A 2EO3A 3ZNIA 3T04A 2YSXA 3VS5A 1SKJA 1A1EA 2CI9A 2JYQA 5EG3B 3MXCA 3OB2B 4WWQA 4LUEA 4OHLA 1O4AA 2IZVA 4JGHA 1O4LA 1BFJA 1AD5A 1CWDL 4JEGA 2DX0A 1KA7A 2ABLA 1AOUF 1R1QA 4DGPA 1SHDA 2DLZA 1O4MA 1WQUA 3VRQA 1K9AA 1OPLA 5KAZA 1OPKA 1P13A 2L6KA 3PFVA 3S8LA 3PSJA 2XP1A 2CR4A 1O4PA 4M4ZA 3K2MA 4DGXA 4TZIA 1CSZA 1R1SA 3M7FA 2PTKA 4EY0A 2EO6A 5GJHA 1MILA 2OQ1A 1LUMA 3OB1B 3N84A 1O4OA 1NRVA 1SPRA 1O4GA 4FL2A 1BHHB 3PS5A 2EU0A 3IN8A 5EEQA 5EHRA 1O4FA 1Y1UA 1UURA 3PQZA 1D4WA 4QSYA 1LCJA 2K79B 1ZFPE 4FBNA 2LCTA 2RMXA 1BLKA 3EAZA 1O45A 2GSBA 1HCSB 2YU7A 4K2RA 1G83A 1F2FA 1O46A 1FBZA 4OHDA 5DF6A 4FL3A 1FMKA 2PLDA 4H1OA 2HUWA 2DVJA 1H9OA 3S9KA 1O47A 2EYZA 3S8OA 1LKKA 3HHMB 3K2TA 5HKZA 1FYRA 4U17A 3TKZA 3N8MA 3CD3A 3QWYA 2MQIA 2EYYA 3IN7A 1O4KA 1JWOA 2CRHA 3US4A 5I6VA 4GPLB 1LUNA 1O44A 1BF5A 2QMSA 5J3XA 2H46E 4GL9E 2CS0A 4OHHA 4F59A 1AYAA 1O41A 2AOBA 1LKLA 3LYVA 2L4KA 1GRIA 1I3ZA 1X0NA 1O4QA 1BKLA 1X6CA 1BKMA 3BUMB 1O4NA 1AYBA 4P9VA 3GXWA 1OO3A 2KK6A 3PSKA 1M27A 2LQWA 1O4IA 3BKBA 1MW4A 1BHFA 5AXIA 2CI8A 4OHEA 2EYVA 1TZEE 1KC2A
chains in the Genus database with same CATH topology
1KA6A 2H8HA 3QWXX 3VS2A 2HMHA 2HDVA 1X27A 5HKWA 4X6SA 1SHBA 3KFJA 3VS3A 2HDXA 4XZ0A 1RQQC 1AOTF 3VRPA 2BBUA 5AULA 3OP0A 5HKYA 3BUWB 1A08A 2RSYA 3BUNB 2LQNA 2RORA 1PICA 4LUDA 2OZOA 3UYOA 3EACA 1SHAA 3CWGA 4JE4A 1D1ZA 3CXLA 1O43A 1KSWA 1BMBA 1Z3KA 4E93A 4E68A 5D0JA 5DC9A 1BFIA 3HCKA 1JYQA 1F1WA 2C9WA 3N7YA 1IS0A 4L1BB 4XZ1A 1YVLA 2GE9A 2MRJA 1NZLA 5DC0B 1LUIA 2PNBA 1B47A 1JYRA 5BO4A 3PLFB 5IBMA 2C0IA 2AUGA 2C0TA 1XA6A 4NWFA 1OO4A 2B3OA 3VGOA 1QADA 2L3TA 3IMDA 1CJ1A 2MK2A 1A81A 2IUIA 1O4DA 2EOBA 4GWFA 1BG1A 3GQIB 3MAZA 2K7AB 4A4BA 3BUXB 3IMJA 1TCEA 1A1CA 3NHNA 4D8KA 1SPSA 3C7IA 4U1PA 2CIAA 3S8NA 2PLEA 1D4TA 2VIFA 2SHPA 1CWEA 1A1BA 1FBVA 4A4CA 2HCKA 4EIHA 1AYCA 5CDWA 1O49A 3VRNA 2ETZA 2H5KA 1A09A 1FHSA 1GHUA 1RPYA 1O42A 2AOAA 2DM0A 2EL8A 1LUKA 2ECDA 2LNXA 1O4EA 2DCRA 3GXXA 2KNOA 1O4BA 3CBLA 2Y3AB 1R1PA 1Y57A 1UUSA 4P9ZA 4F5BA 2DLYA 1JYUA 2PNAA 5IBSA 2MC1A 1YVHA 1FU6A 1O4JA 5GJIA 3VRRA 3VS7A 1AYDA 1O4HA 1IJRA 1BLJA 2LNWA 3VRZA 1M61A 3VS1A 3VS4A 2RVFA 4K44A 1QCFA 2SRCA 3VRYA 1BHHA 1A07A 5DC4A 1CSYA 2C0OA 1FU5A 2Y1NA 1NZVA 4NWGA 1O4CA 3PJPA 1LCKA 3UF4A 2MRKA 3BUOB 4ROJA 5EELA 1JU5A 2IUGA 3TL0A 3VS6A 3WA4A 2CBLA 2IUHA 2FO0A 3MXYA 1AB2A 1QG1E 2FCIA 3OVEA 1HCTB 4OHIA 1O4RA 2EKXA 1RJAA 5EHPA 4K11A 1A1AA 3VS0A 3OV1A 3HIZB 4H34A 3VROA 2Y1MA 4K45A 1BM2A 4F5AA 1O48A 2EO3A 3ZNIA 3T04A 2YSXA 3VS5A 1SKJA 1A1EA 2CI9A 2JYQA 5EG3B 3MXCA 3OB2B 4WWQA 4LUEA 4OHLA 1O4AA 2IZVA 4JGHA 1O4LA 1BFJA 1AD5A 1CWDL 4JEGA 2DX0A 1KA7A 2ABLA 1AOUF 1R1QA 4DGPA 1SHDA 2DLZA 1O4MA 1WQUA 3VRQA 1K9AA 1OPLA 5KAZA 1OPKA 1P13A 2L6KA 3PFVA 3S8LA 3PSJA 2XP1A 2CR4A 1O4PA 4M4ZA 3K2MA 4DGXA 4TZIA 1CSZA 1R1SA 3M7FA 2PTKA 4EY0A 2EO6A 5GJHA 1MILA 2OQ1A 1LUMA 3OB1B 3N84A 1O4OA 1NRVA 1SPRA 1O4GA 4FL2A 1BHHB 3PS5A 2EU0A 3IN8A 5EEQA 5EHRA 1O4FA 1Y1UA 1UURA 3PQZA 1D4WA 4QSYA 1LCJA 2K79B 1ZFPE 4FBNA 2LCTA 2RMXA 1BLKA 3EAZA 1O45A 2GSBA 1HCSB 2YU7A 4K2RA 1G83A 1F2FA 1O46A 1FBZA 4OHDA 5DF6A 4FL3A 1FMKA 2PLDA 4H1OA 2HUWA 2DVJA 1H9OA 3S9KA 1O47A 2EYZA 3S8OA 1LKKA 3HHMB 5HKZA 1FYRA 4U17A 3TKZA 3N8MA 3CD3A 3QWYA 2MQIA 2EYYA 3IN7A 1O4KA 1JWOA 2CRHA 3US4A 5I6VA 4GPLB 1LUNA 1O44A 1BF5A 2QMSA 5J3XA 2H46E 4GL9E 2CS0A 4OHHA 4F59A 1AYAA 1O41A 2AOBA 1LKLA 2L4KA 1GRIA 1I3ZA 1X0NA 1O4QA 1BKLA 1X6CA 1BKMA 3BUMB 1O4NA 1AYBA 4P9VA 3GXWA 1OO3A 2KK6A 3PSKA 1M27A 2LQWA 1O4IA 3BKBA 1MW4A 1BHFA 5AXIA 2CI8A 4OHEA 2EYVA 1TZEE 1KC2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KA6 A;  2H8H A;  3QWX X;  3VS2 A;  2HMH A;  2HDV A;  1X27 A;  5HKW A;  4X6S A;  1SHB A;  3KFJ A;  3VS3 A;  2HDX A;  4XZ0 A;  1RQQ C;  1AOT F;  3VRP A;  2BBU A;  5AUL A;  3OP0 A;  5HKY A;  3BUW B;  1A08 A;  2RSY A;  3BUN B;  2LQN A;  2ROR A;  1PIC A;  4LUD A;  2OZO A;  3UYO A;  3EAC A;  1SHA A;  3CWG A;  4JE4 A;  1D1Z A;  3CXL A;  1O43 A;  1KSW A;  1BMB A;  1Z3K A;  4E93 A;  4E68 A;  5D0J A;  5DC9 A;  1BFI A;  3HCK A;  1JYQ A;  1F1W A;  2C9W A;  3N7Y A;  1IS0 A;  4L1B B;  4XZ1 A;  1YVL A;  2GE9 A;  2MRJ A;  1NZL A;  5DC0 B;  1LUI A;  2PNB A;  1B47 A;  1JYR A;  5BO4 A;  3PLF B;  5IBM A;  2C0I A;  2AUG A;  2C0T A;  1XA6 A;  4NWF A;  1OO4 A;  2B3O A;  3VGO A;  1QAD A;  2L3T A;  3IMD A;  1CJ1 A;  2MK2 A;  1A81 A;  2IUI A;  1O4D A;  2EOB A;  4GWF A;  1BG1 A;  3GQI B;  3MAZ A;  2K7A B;  4A4B A;  3BUX B;  3IMJ A;  1TCE A;  1A1C A;  3NHN A;  4D8K A;  1SPS A;  3C7I A;  4U1P A;  2CIA A;  3S8N A;  2PLE A;  1D4T A;  2VIF A;  2SHP A;  1CWE A;  1A1B A;  1FBV A;  4A4C A;  2HCK A;  4EIH A;  1AYC A;  5CDW A;  1O49 A;  3VRN A;  2ETZ A;  2H5K A;  1A09 A;  1FHS A;  1GHU A;  1RPY A;  1O42 A;  2AOA A;  2DM0 A;  2EL8 A;  1LUK A;  2ECD A;  2LNX A;  1O4E A;  2DCR A;  3GXX A;  2KNO A;  1O4B A;  3CBL A;  2Y3A B;  1R1P A;  1Y57 A;  1UUS A;  4P9Z A;  4F5B A;  2DLY A;  1JYU A;  2PNA A;  5IBS A;  2MC1 A;  1YVH A;  1FU6 A;  1O4J A;  5GJI A;  3VRR A;  3VS7 A;  1AYD A;  1O4H A;  1IJR A;  1BLJ A;  2LNW A;  3VRZ A;  1M61 A;  3VS1 A;  3VS4 A;  2RVF A;  4K44 A;  1QCF A;  2SRC A;  3VRY A;  1BHH A;  1A07 A;  5DC4 A;  1CSY A;  2C0O A;  1FU5 A;  2Y1N A;  1NZV A;  4NWG A;  1O4C A;  3PJP A;  1LCK A;  3UF4 A;  2MRK A;  3BUO B;  4ROJ A;  5EEL A;  1JU5 A;  2IUG A;  3TL0 A;  3VS6 A;  3WA4 A;  2CBL A;  2IUH A;  2FO0 A;  3MXY A;  1AB2 A;  1QG1 E;  2FCI A;  3OVE A;  1HCT B;  4OHI A;  1O4R A;  2EKX A;  1RJA A;  5EHP A;  4K11 A;  1A1A A;  3VS0 A;  3OV1 A;  3HIZ B;  4H34 A;  3VRO A;  2Y1M A;  4K45 A;  1BM2 A;  4F5A A;  1O48 A;  2EO3 A;  3ZNI A;  3T04 A;  2YSX A;  3VS5 A;  1SKJ A;  1A1E A;  2CI9 A;  2JYQ A;  5EG3 B;  3MXC A;  3OB2 B;  4WWQ A;  4LUE A;  4OHL A;  1O4A A;  2IZV A;  4JGH A;  1O4L A;  1BFJ A;  1AD5 A;  1CWD L;  4JEG A;  2DX0 A;  1KA7 A;  2ABL A;  1AOU F;  1R1Q A;  4DGP A;  1SHD A;  2DLZ A;  1O4M A;  1WQU A;  3VRQ A;  1K9A A;  1OPL A;  5KAZ A;  1OPK A;  1P13 A;  2L6K A;  3PFV A;  3S8L A;  3PSJ A;  2XP1 A;  2CR4 A;  1O4P A;  4M4Z A;  3K2M A;  4DGX A;  4TZI A;  1CSZ A;  1R1S A;  3M7F A;  2PTK A;  4EY0 A;  2EO6 A;  5GJH A;  1MIL A;  2OQ1 A;  1LUM A;  3OB1 B;  3N84 A;  1O4O A;  1NRV A;  1SPR A;  1O4G A;  4FL2 A;  1BHH B;  3PS5 A;  2EU0 A;  3IN8 A;  5EEQ A;  5EHR A;  1O4F A;  1Y1U A;  1UUR A;  3PQZ A;  1D4W A;  4QSY A;  1LCJ A;  2K79 B;  1ZFP E;  4FBN A;  2LCT A;  2RMX A;  1BLK A;  3EAZ A;  1O45 A;  2GSB A;  1HCS B;  2YU7 A;  4K2R A;  1G83 A;  1F2F A;  1O46 A;  1FBZ A;  4OHD A;  5DF6 A;  4FL3 A;  1FMK A;  2PLD A;  4H1O A;  2HUW A;  2DVJ A;  1H9O A;  3S9K A;  1O47 A;  2EYZ A;  3S8O A;  1LKK A;  3HHM B;  5HKZ A;  1FYR A;  4U17 A;  3TKZ A;  3N8M A;  3CD3 A;  3QWY A;  2MQI A;  2EYY A;  3IN7 A;  1O4K A;  1JWO A;  2CRH A;  3US4 A;  5I6V A;  4GPL B;  1LUN A;  1O44 A;  1BF5 A;  2QMS A;  5J3X A;  2H46 E;  4GL9 E;  2CS0 A;  4OHH A;  4F59 A;  1AYA A;  1O41 A;  2AOB A;  1LKL A;  2L4K A;  1GRI A;  1I3Z A;  1X0N A;  1O4Q A;  1BKL A;  1X6C A;  1BKM A;  3BUM B;  1O4N A;  1AYB A;  4P9V A;  3GXW A;  1OO3 A;  2KK6 A;  3PSK A;  1M27 A;  2LQW A;  1O4I A;  3BKB A;  1MW4 A;  1BHF A;  5AXI A;  2CI8 A;  4OHE A;  2EYV A;  1TZE E;  1KC2 A; 
#chains in the Genus database with same CATH topology
 1KA6 A;  2H8H A;  3QWX X;  3VS2 A;  2HMH A;  2HDV A;  1X27 A;  5HKW A;  4X6S A;  1SHB A;  3KFJ A;  3VS3 A;  2HDX A;  4XZ0 A;  1RQQ C;  1AOT F;  3VRP A;  2BBU A;  5AUL A;  3OP0 A;  5HKY A;  3BUW B;  1A08 A;  2KGY A;  2RSY A;  2LRA A;  3BUN B;  2LQN A;  2ROR A;  1PIC A;  4LUD A;  2OZO A;  3UYO A;  3EAC A;  1SHA A;  3CWG A;  4JE4 A;  1D1Z A;  3CXL A;  1O43 A;  1KSW A;  1BMB A;  1Z3K A;  4E93 A;  4E68 A;  5D0J A;  5DC9 A;  1BFI A;  3HCK A;  1JYQ A;  1F1W A;  2C9W A;  3N7Y A;  1IS0 A;  4L1B B;  4XZ1 A;  1YVL A;  2GE9 A;  2MRJ A;  1NZL A;  5DC0 B;  1LUI A;  2PNB A;  1B47 A;  1JYR A;  5BO4 A;  3PLF B;  5IBM A;  2C0I A;  2AUG A;  2C0T A;  1XA6 A;  4NWF A;  1OO4 A;  2B3O A;  3VGO A;  1QAD A;  2L3T A;  3IMD A;  1CJ1 A;  2MK2 A;  1A81 A;  2IUI A;  1O4D A;  2EOB A;  4GWF A;  1BG1 A;  3GQI B;  3MAZ A;  2K7A B;  4A4B A;  3BUX B;  3IMJ A;  1TCE A;  1A1C A;  3NHN A;  4D8K A;  1SPS A;  3C7I A;  4U1P A;  2CIA A;  3S8N A;  2PLE A;  1D4T A;  2VIF A;  2SHP A;  1CWE A;  1A1B A;  1FBV A;  4A4C A;  2HCK A;  4EIH A;  1AYC A;  5CDW A;  1O49 A;  3VRN A;  2ETZ A;  2H5K A;  1A09 A;  1FHS A;  1GHU A;  1RPY A;  1O42 A;  2AOA A;  2DM0 A;  2EL8 A;  1LUK A;  2ECD A;  2LNX A;  1O4E A;  2DCR A;  3GXX A;  2KNO A;  1O4B A;  3CBL A;  2Y3A B;  1R1P A;  1Y57 A;  1UUS A;  4P9Z A;  4F5B A;  2DLY A;  1JYU A;  2PNA A;  5IBS A;  2MC1 A;  1YVH A;  1FU6 A;  1O4J A;  5GJI A;  3VRR A;  3VS7 A;  1AYD A;  1O4H A;  1IJR A;  1BLJ A;  2LNW A;  3VRZ A;  1M61 A;  3VS1 A;  3VS4 A;  2RVF A;  4K44 A;  1QCF A;  2SRC A;  3VRY A;  1BHH A;  1A07 A;  5DC4 A;  1CSY A;  2C0O A;  1FU5 A;  2Y1N A;  1NZV A;  4NWG A;  1O4C A;  3PJP A;  1LCK A;  3UF4 A;  2MRK A;  3BUO B;  4ROJ A;  5EEL A;  1JU5 A;  2IUG A;  3TL0 A;  3VS6 A;  3WA4 A;  2CBL A;  2IUH A;  2FO0 A;  3MXY A;  1AB2 A;  1QG1 E;  2FCI A;  3OVE A;  1HCT B;  4OHI A;  1O4R A;  2EKX A;  1RJA A;  5EHP A;  4K11 A;  1A1A A;  3VS0 A;  3OV1 A;  3HIZ B;  4H34 A;  3VRO A;  2Y1M A;  4K45 A;  1BM2 A;  4F5A A;  1O48 A;  2EO3 A;  3ZNI A;  3T04 A;  2YSX A;  3VS5 A;  1SKJ A;  1A1E A;  2CI9 A;  2JYQ A;  5EG3 B;  3MXC A;  3OB2 B;  4WWQ A;  4LUE A;  4OHL A;  1O4A A;  2IZV A;  4JGH A;  1O4L A;  1BFJ A;  1AD5 A;  1CWD L;  4JEG A;  2DX0 A;  1KA7 A;  2ABL A;  1AOU F;  1R1Q A;  4DGP A;  1SHD A;  2DLZ A;  1O4M A;  1WQU A;  3VRQ A;  1K9A A;  1OPL A;  5KAZ A;  1OPK A;  1P13 A;  2L6K A;  3PFV A;  3S8L A;  3PSJ A;  2XP1 A;  2CR4 A;  1O4P A;  4M4Z A;  3K2M A;  4DGX A;  4TZI A;  1CSZ A;  1R1S A;  3M7F A;  2PTK A;  4EY0 A;  2EO6 A;  5GJH A;  1MIL A;  2OQ1 A;  1LUM A;  3OB1 B;  3N84 A;  1O4O A;  1NRV A;  1SPR A;  1O4G A;  4FL2 A;  1BHH B;  3PS5 A;  2EU0 A;  3IN8 A;  5EEQ A;  5EHR A;  1O4F A;  1Y1U A;  1UUR A;  3PQZ A;  1D4W A;  4QSY A;  1LCJ A;  2K79 B;  1ZFP E;  4FBN A;  2LCT A;  2RMX A;  1BLK A;  3EAZ A;  1O45 A;  2GSB A;  1HCS B;  2YU7 A;  4K2R A;  1G83 A;  1F2F A;  1O46 A;  1FBZ A;  4OHD A;  5DF6 A;  4FL3 A;  1FMK A;  2PLD A;  4H1O A;  2HUW A;  2DVJ A;  1H9O A;  3S9K A;  1O47 A;  2EYZ A;  3S8O A;  1LKK A;  3HHM B;  3K2T A;  5HKZ A;  1FYR A;  4U17 A;  3TKZ A;  3N8M A;  3CD3 A;  3QWY A;  2MQI A;  2EYY A;  3IN7 A;  1O4K A;  1JWO A;  2CRH A;  3US4 A;  5I6V A;  4GPL B;  1LUN A;  1O44 A;  1BF5 A;  2QMS A;  5J3X A;  2H46 E;  4GL9 E;  2CS0 A;  4OHH A;  4F59 A;  1AYA A;  1O41 A;  2AOB A;  1LKL A;  3LYV A;  2L4K A;  1GRI A;  1I3Z A;  1X0N A;  1O4Q A;  1BKL A;  1X6C A;  1BKM A;  3BUM B;  1O4N A;  1AYB A;  4P9V A;  3GXW A;  1OO3 A;  2KK6 A;  3PSK A;  1M27 A;  2LQW A;  1O4I A;  3BKB A;  1MW4 A;  1BHF A;  5AXI A;  2CI8 A;  4OHE A;  2EYV A;  1TZE E;  1KC2 A; 
#chains in the Genus database with same CATH homology
 1KA6 A;  2H8H A;  3QWX X;  3VS2 A;  2HMH A;  2HDV A;  1X27 A;  5HKW A;  4X6S A;  1SHB A;  3KFJ A;  3VS3 A;  2HDX A;  4XZ0 A;  1RQQ C;  1AOT F;  3VRP A;  2BBU A;  5AUL A;  3OP0 A;  5HKY A;  3BUW B;  1A08 A;  2RSY A;  3BUN B;  2LQN A;  2ROR A;  1PIC A;  4LUD A;  2OZO A;  3UYO A;  3EAC A;  1SHA A;  3CWG A;  4JE4 A;  1D1Z A;  3CXL A;  1O43 A;  1KSW A;  1BMB A;  1Z3K A;  4E93 A;  4E68 A;  5D0J A;  5DC9 A;  1BFI A;  3HCK A;  1JYQ A;  1F1W A;  2C9W A;  3N7Y A;  1IS0 A;  4L1B B;  4XZ1 A;  1YVL A;  2GE9 A;  2MRJ A;  1NZL A;  5DC0 B;  1LUI A;  2PNB A;  1B47 A;  1JYR A;  5BO4 A;  3PLF B;  5IBM A;  2C0I A;  2AUG A;  2C0T A;  1XA6 A;  4NWF A;  1OO4 A;  2B3O A;  3VGO A;  1QAD A;  2L3T A;  3IMD A;  1CJ1 A;  2MK2 A;  1A81 A;  2IUI A;  1O4D A;  2EOB A;  4GWF A;  1BG1 A;  3GQI B;  3MAZ A;  2K7A B;  4A4B A;  3BUX B;  3IMJ A;  1TCE A;  1A1C A;  3NHN A;  4D8K A;  1SPS A;  3C7I A;  4U1P A;  2CIA A;  3S8N A;  2PLE A;  1D4T A;  2VIF A;  2SHP A;  1CWE A;  1A1B A;  1FBV A;  4A4C A;  2HCK A;  4EIH A;  1AYC A;  5CDW A;  1O49 A;  3VRN A;  2ETZ A;  2H5K A;  1A09 A;  1FHS A;  1GHU A;  1RPY A;  1O42 A;  2AOA A;  2DM0 A;  2EL8 A;  1LUK A;  2ECD A;  2LNX A;  1O4E A;  2DCR A;  3GXX A;  2KNO A;  1O4B A;  3CBL A;  2Y3A B;  1R1P A;  1Y57 A;  1UUS A;  4P9Z A;  4F5B A;  2DLY A;  1JYU A;  2PNA A;  5IBS A;  2MC1 A;  1YVH A;  1FU6 A;  1O4J A;  5GJI A;  3VRR A;  3VS7 A;  1AYD A;  1O4H A;  1IJR A;  1BLJ A;  2LNW A;  3VRZ A;  1M61 A;  3VS1 A;  3VS4 A;  2RVF A;  4K44 A;  1QCF A;  2SRC A;  3VRY A;  1BHH A;  1A07 A;  5DC4 A;  1CSY A;  2C0O A;  1FU5 A;  2Y1N A;  1NZV A;  4NWG A;  1O4C A;  3PJP A;  1LCK A;  3UF4 A;  2MRK A;  3BUO B;  4ROJ A;  5EEL A;  1JU5 A;  2IUG A;  3TL0 A;  3VS6 A;  3WA4 A;  2CBL A;  2IUH A;  2FO0 A;  3MXY A;  1AB2 A;  1QG1 E;  2FCI A;  3OVE A;  1HCT B;  4OHI A;  1O4R A;  2EKX A;  1RJA A;  5EHP A;  4K11 A;  1A1A A;  3VS0 A;  3OV1 A;  3HIZ B;  4H34 A;  3VRO A;  2Y1M A;  4K45 A;  1BM2 A;  4F5A A;  1O48 A;  2EO3 A;  3ZNI A;  3T04 A;  2YSX A;  3VS5 A;  1SKJ A;  1A1E A;  2CI9 A;  2JYQ A;  5EG3 B;  3MXC A;  3OB2 B;  4WWQ A;  4LUE A;  4OHL A;  1O4A A;  2IZV A;  4JGH A;  1O4L A;  1BFJ A;  1AD5 A;  1CWD L;  4JEG A;  2DX0 A;  1KA7 A;  2ABL A;  1AOU F;  1R1Q A;  4DGP A;  1SHD A;  2DLZ A;  1O4M A;  1WQU A;  3VRQ A;  1K9A A;  1OPL A;  5KAZ A;  1OPK A;  1P13 A;  2L6K A;  3PFV A;  3S8L A;  3PSJ A;  2XP1 A;  2CR4 A;  1O4P A;  4M4Z A;  3K2M A;  4DGX A;  4TZI A;  1CSZ A;  1R1S A;  3M7F A;  2PTK A;  4EY0 A;  2EO6 A;  5GJH A;  1MIL A;  2OQ1 A;  1LUM A;  3OB1 B;  3N84 A;  1O4O A;  1NRV A;  1SPR A;  1O4G A;  4FL2 A;  1BHH B;  3PS5 A;  2EU0 A;  3IN8 A;  5EEQ A;  5EHR A;  1O4F A;  1Y1U A;  1UUR A;  3PQZ A;  1D4W A;  4QSY A;  1LCJ A;  2K79 B;  1ZFP E;  4FBN A;  2LCT A;  2RMX A;  1BLK A;  3EAZ A;  1O45 A;  2GSB A;  1HCS B;  2YU7 A;  4K2R A;  1G83 A;  1F2F A;  1O46 A;  1FBZ A;  4OHD A;  5DF6 A;  4FL3 A;  1FMK A;  2PLD A;  4H1O A;  2HUW A;  2DVJ A;  1H9O A;  3S9K A;  1O47 A;  2EYZ A;  3S8O A;  1LKK A;  3HHM B;  5HKZ A;  1FYR A;  4U17 A;  3TKZ A;  3N8M A;  3CD3 A;  3QWY A;  2MQI A;  2EYY A;  3IN7 A;  1O4K A;  1JWO A;  2CRH A;  3US4 A;  5I6V A;  4GPL B;  1LUN A;  1O44 A;  1BF5 A;  2QMS A;  5J3X A;  2H46 E;  4GL9 E;  2CS0 A;  4OHH A;  4F59 A;  1AYA A;  1O41 A;  2AOB A;  1LKL A;  2L4K A;  1GRI A;  1I3Z A;  1X0N A;  1O4Q A;  1BKL A;  1X6C A;  1BKM A;  3BUM B;  1O4N A;  1AYB A;  4P9V A;  3GXW A;  1OO3 A;  2KK6 A;  3PSK A;  1M27 A;  2LQW A;  1O4I A;  3BKB A;  1MW4 A;  1BHF A;  5AXI A;  2CI8 A;  4OHE A;  2EYV A;  1TZE E;  1KC2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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