4JE4A

Crystal structure of monobody nsa1/shp2 n-sh2 domain complex
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
102
structure length
102
Chain Sequence
SRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.
pubmed doi rcsb
molecule tags Signaling protein/protein binding
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 27
structure length 102
sequence length 102
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2013-02-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4je4A00
1O4MA 3MAZA 4FL2A 4OHLA 1O44A 3VS3A 2GSBA 1CWEA 4K44A 3PSJA 3VGOA 2LNXA 1O42A 1R1PA 3EAZA 2RSYA 1SPSA 3S8LA 1QG1E 2YSXA 1O4KA 4QSYA 1R1QA 4TZIA 4K2RA 2EU0A 1O4PA 1A08A 1LUNA 2H8HA 1MILA 1O48A 1JYRA 2IUHA 5EHRA 4U17A 2EYVA 1UUSA 2HDVA 1BM2A 1G83A 3HCKA 2VIFA 3PSKA 1JWOA 1ZFPE 4JEGA 2IUIA 2DLYA 2LQNA 3CD3A 5KAZA 1A1AA 4XZ0A 1BLJA 4NWFA 2JYQA 3GXXA 1O4FA 1O4IA 2HCKA 4M4ZA 5I6VA 5EG3B 1R1SA 3QWYA 5EELA 1LKKA 3PQZA 4K11A 1BF5A 1KC2A 3PFVA 1BG1A 1BLKA 3PS5A 1WQUA 1JYUA 4D8KA 3HIZB 1AYBA 3ZNIA 1A09A 3M7FA 2K7AB 1D1ZA 2HDXA 2H46E 3VS4A 1AYAA 3OB2B 1O4AA 2MRJA 4F59A 1HCTB 1O43A 1LUIA 2EYZA 4DGXA 1NZVA 3BUMB 2C0OA 2HMHA 4FL3A 1H9OA 1NZLA 2OZOA 3QWXX 1A1BA 1A81A 3VRPA 2BBUA 1LUKA 3IN8A 3MXCA 4H34A 1PICA 1Y57A 5EHPA 1HCSB 1I3ZA 3TL0A 1SHDA 2YU7A 1CJ1A 1SHAA 1X0NA 4LUEA 1LCKA 1X27A 5DC9A 3CXLA 3GQIB 4OHIA 2OQ1A 1O4QA 3US4A 1BFJA 2HUWA 1BHHB 2C0TA 3BUXB 2C0IA 1NRVA 1FBVA 3VS6A 1YVLA 2H5KA 2Y3AB 4JGHA 4P9ZA 1KA6A 2MC1A 2DLZA 1O45A 2SHPA 1XA6A 1SPRA 3N7YA 4X6SA 3VS2A 5AXIA 4NWGA 1O4BA 5AULA 5EEQA 1BHHA 1F1WA 1O47A 1O4CA 3OP0A 1RQQC 2CBLA 1CSZA 3WA4A 1O46A 1O4RA 1CSYA 2DCRA 5J3XA 1RJAA 2CR4A 2ETZA 3CBLA 3OVEA 1Z3KA 4OHHA 5HKZA 4EIHA 3VRNA 1O49A 1KSWA 1FU6A 3S8OA 3EACA 2LNWA 5IBSA 5CDWA 4K45A 5GJIA 1SKJA 1JYQA 1RPYA 4E68A 1BKLA 4OHDA 1O4JA 1P13A 2EO6A 3VRQA 1AYDA 2AOAA 2CIAA 1F2FA 3K2MA 4E93A 3VS5A 2GE9A 2KNOA 3VRYA 4DGPA 1IS0A 1FBZA 3T04A 1LUMA 3N8MA 4F5BA 1O4NA 3OV1A 4OHEA 2FCIA 1AOTF 4U1PA 1D4WA 1TCEA 1O4LA 1QADA 3C7IA 1AB2A 1KA7A 3VS0A 3CWGA 5HKYA 1GHUA 2K79B 2PNBA 2DVJA 1AD5A 4P9VA 2Y1NA 2EYYA 2XP1A 3VROA 3NHNA 1LCJA 4EY0A 1JU5A 4JE4A 3BUWB 2PNAA 2CRHA 2EKXA 3VRZA 1LKLA 2RVFA 4L1BB 3IN7A 4GPLB 4F5AA 1GRIA 3S9KA 2CI8A 1OO4A 1TZEE 1A1EA 4A4CA 1M61A 4ROJA 2RMXA 3S8NA 1M27A 4WWQA 1A1CA 1B47A 2QMSA 1SHBA 1YVHA 1A07A 1O4OA 4GWFA 1AYCA 2CI9A 2EOBA 5D0JA 3HHMB 2C9WA 1OO3A 3PJPA 1FHSA 1O4DA 2L6KA 3UYOA 1CWDL 1O4HA 3GXWA 3MXYA 1FYRA 2EL8A 3PLFB 5DC4A 2L3TA 2CS0A 2IZVA 2KK6A 2L4KA 2MK2A 1FU5A 1OPKA 2DM0A 4XZ1A 2Y1MA 1BHFA 1UURA 2LCTA 4FBNA 3VS1A 1X6CA 2PLEA 1AOUF 1K9AA 1O4EA 5IBMA 2PLDA 2AOBA 2AUGA 2MRKA 3IMJA 5GJHA 1IJRA 5HKWA 3KFJA 2RORA 5DC0B 2SRCA 2PTKA 4H1OA 1O4GA 2ABLA 3BKBA 1OPLA 2DX0A 1D4TA 5BO4A 1BKMA 2FO0A 1FMKA 2ECDA 3TKZA 3N84A 4A4BA 5DF6A 1QCFA 4LUDA 3IMDA 3OB1B 3VRRA 2LQWA 3VS7A 4GL9E 3BUOB 2IUGA 2B3OA 1O41A 2MQIA 3UF4A 3BUNB 1Y1UA 1BMBA 2EO3A 1MW4A 1BFIA
chains in the Genus database with same CATH superfamily
1O4MA 3MAZA 4FL2A 4OHLA 1O44A 3VS3A 2GSBA 1CWEA 4K44A 3PSJA 3VGOA 2LNXA 1O42A 1R1PA 3EAZA 2RSYA 1SPSA 3S8LA 1QG1E 2YSXA 1O4KA 4QSYA 1R1QA 4TZIA 4K2RA 2EU0A 1O4PA 1A08A 1LUNA 2H8HA 1MILA 1O48A 1JYRA 2IUHA 5EHRA 4U17A 2EYVA 1UUSA 2HDVA 1BM2A 1G83A 3HCKA 2VIFA 3PSKA 1JWOA 1ZFPE 4JEGA 2IUIA 2DLYA 2LQNA 3CD3A 5KAZA 1A1AA 4XZ0A 1BLJA 4NWFA 2JYQA 3GXXA 1O4FA 1O4IA 2HCKA 4M4ZA 5I6VA 5EG3B 1R1SA 3QWYA 5EELA 1LKKA 3PQZA 4K11A 1BF5A 1KC2A 3PFVA 1BG1A 1BLKA 3PS5A 1WQUA 1JYUA 4D8KA 3HIZB 1AYBA 3ZNIA 1A09A 3M7FA 2K7AB 1D1ZA 2HDXA 2H46E 3VS4A 1AYAA 3OB2B 1O4AA 2MRJA 4F59A 1HCTB 1O43A 1LUIA 2EYZA 4DGXA 1NZVA 3BUMB 2C0OA 2HMHA 4FL3A 1H9OA 1NZLA 2OZOA 3QWXX 1A1BA 1A81A 3VRPA 2BBUA 1LUKA 3IN8A 3MXCA 4H34A 1PICA 1Y57A 5EHPA 1HCSB 1I3ZA 3TL0A 1SHDA 2YU7A 1CJ1A 1SHAA 1X0NA 4LUEA 1LCKA 1X27A 5DC9A 3CXLA 3GQIB 4OHIA 2OQ1A 1O4QA 3US4A 1BFJA 2HUWA 1BHHB 2C0TA 3BUXB 2C0IA 1NRVA 3K2TA 2KGYA 1FBVA 3VS6A 1YVLA 2H5KA 2Y3AB 4JGHA 4P9ZA 1KA6A 2MC1A 2DLZA 1O45A 2SHPA 1XA6A 1SPRA 3N7YA 4X6SA 3VS2A 5AXIA 4NWGA 1O4BA 5AULA 5EEQA 1BHHA 1F1WA 1O47A 1O4CA 3OP0A 1RQQC 2CBLA 1CSZA 3WA4A 1O46A 1O4RA 1CSYA 2DCRA 5J3XA 1RJAA 2CR4A 2ETZA 3CBLA 3OVEA 1Z3KA 4OHHA 5HKZA 4EIHA 3VRNA 1O49A 1KSWA 1FU6A 3S8OA 3EACA 2LNWA 5IBSA 5CDWA 4K45A 5GJIA 1SKJA 1JYQA 1RPYA 4E68A 1BKLA 4OHDA 1O4JA 1P13A 2EO6A 3VRQA 1AYDA 2AOAA 2CIAA 1F2FA 3K2MA 4E93A 3VS5A 2GE9A 2KNOA 3VRYA 4DGPA 1IS0A 1FBZA 3T04A 1LUMA 3N8MA 4F5BA 1O4NA 3OV1A 4OHEA 2FCIA 1AOTF 4U1PA 1D4WA 1TCEA 1O4LA 1QADA 3C7IA 1AB2A 1KA7A 3VS0A 3CWGA 5HKYA 1GHUA 2K79B 2PNBA 2DVJA 1AD5A 4P9VA 2Y1NA 2EYYA 2XP1A 3VROA 3NHNA 1LCJA 4EY0A 1JU5A 4JE4A 3BUWB 2PNAA 2LRAA 2CRHA 2EKXA 3VRZA 1LKLA 2RVFA 4L1BB 3IN7A 4GPLB 4F5AA 1GRIA 3S9KA 2CI8A 1OO4A 1TZEE 1A1EA 4A4CA 1M61A 4ROJA 2RMXA 3S8NA 1M27A 4WWQA 1A1CA 1B47A 2QMSA 1SHBA 1YVHA 1A07A 1O4OA 4GWFA 1AYCA 2CI9A 2EOBA 5D0JA 3HHMB 2C9WA 1OO3A 3PJPA 1FHSA 1O4DA 2L6KA 3UYOA 1CWDL 1O4HA 3GXWA 3MXYA 1FYRA 2EL8A 3PLFB 5DC4A 2L3TA 2CS0A 2IZVA 2KK6A 2L4KA 2MK2A 1FU5A 1OPKA 2DM0A 4XZ1A 2Y1MA 1BHFA 1UURA 2LCTA 4FBNA 3VS1A 1X6CA 2PLEA 1AOUF 1K9AA 1O4EA 5IBMA 2PLDA 2AOBA 2AUGA 2MRKA 3IMJA 5GJHA 1IJRA 5HKWA 3KFJA 2RORA 5DC0B 2SRCA 2PTKA 4H1OA 1O4GA 2ABLA 3BKBA 1OPLA 2DX0A 1D4TA 5BO4A 1BKMA 2FO0A 1FMKA 2ECDA 3TKZA 3N84A 4A4BA 5DF6A 1QCFA 4LUDA 3IMDA 3OB1B 3VRRA 2LQWA 3VS7A 4GL9E 3BUOB 2IUGA 2B3OA 3LYVA 1O41A 2MQIA 3UF4A 3BUNB 1Y1UA 1BMBA 2EO3A 1MW4A 1BFIA
chains in the Genus database with same CATH topology
1O4MA 3MAZA 4FL2A 4OHLA 1O44A 3VS3A 2GSBA 1CWEA 4K44A 3PSJA 3VGOA 2LNXA 1O42A 1R1PA 3EAZA 2RSYA 1SPSA 3S8LA 1QG1E 2YSXA 1O4KA 4QSYA 1R1QA 4TZIA 4K2RA 2EU0A 1O4PA 1A08A 1LUNA 2H8HA 1MILA 1O48A 1JYRA 2IUHA 5EHRA 4U17A 2EYVA 1UUSA 2HDVA 1BM2A 1G83A 3HCKA 2VIFA 3PSKA 1JWOA 1ZFPE 4JEGA 2IUIA 2DLYA 2LQNA 3CD3A 5KAZA 1A1AA 4XZ0A 1BLJA 4NWFA 2JYQA 3GXXA 1O4FA 1O4IA 2HCKA 4M4ZA 5I6VA 5EG3B 1R1SA 3QWYA 5EELA 1LKKA 3PQZA 4K11A 1BF5A 1KC2A 3PFVA 1BG1A 1BLKA 3PS5A 1WQUA 1JYUA 4D8KA 3HIZB 1AYBA 3ZNIA 1A09A 3M7FA 2K7AB 1D1ZA 2HDXA 2H46E 3VS4A 1AYAA 3OB2B 1O4AA 2MRJA 4F59A 1HCTB 1O43A 1LUIA 2EYZA 4DGXA 1NZVA 3BUMB 2C0OA 2HMHA 4FL3A 1H9OA 1NZLA 2OZOA 3QWXX 1A1BA 1A81A 3VRPA 2BBUA 1LUKA 3IN8A 3MXCA 4H34A 1PICA 1Y57A 5EHPA 1HCSB 1I3ZA 3TL0A 1SHDA 2YU7A 1CJ1A 1SHAA 1X0NA 4LUEA 1LCKA 1X27A 5DC9A 3CXLA 3GQIB 4OHIA 2OQ1A 1O4QA 3US4A 1BFJA 2HUWA 1BHHB 2C0TA 3BUXB 2C0IA 1NRVA 1FBVA 3VS6A 1YVLA 2H5KA 2Y3AB 4JGHA 4P9ZA 1KA6A 2MC1A 2DLZA 1O45A 2SHPA 1XA6A 1SPRA 3N7YA 4X6SA 3VS2A 5AXIA 4NWGA 1O4BA 5AULA 5EEQA 1BHHA 1F1WA 1O47A 1O4CA 3OP0A 1RQQC 2CBLA 1CSZA 3WA4A 1O46A 1O4RA 1CSYA 2DCRA 5J3XA 1RJAA 2CR4A 2ETZA 3CBLA 3OVEA 1Z3KA 4OHHA 5HKZA 4EIHA 3VRNA 1O49A 1KSWA 1FU6A 3S8OA 3EACA 2LNWA 5IBSA 5CDWA 4K45A 5GJIA 1SKJA 1JYQA 1RPYA 4E68A 1BKLA 4OHDA 1O4JA 1P13A 2EO6A 3VRQA 1AYDA 2AOAA 2CIAA 1F2FA 3K2MA 4E93A 3VS5A 2GE9A 2KNOA 3VRYA 4DGPA 1IS0A 1FBZA 3T04A 1LUMA 3N8MA 4F5BA 1O4NA 3OV1A 4OHEA 2FCIA 1AOTF 4U1PA 1D4WA 1TCEA 1O4LA 1QADA 3C7IA 1AB2A 1KA7A 3VS0A 3CWGA 5HKYA 1GHUA 2K79B 2PNBA 2DVJA 1AD5A 4P9VA 2Y1NA 2EYYA 2XP1A 3VROA 3NHNA 1LCJA 4EY0A 1JU5A 4JE4A 3BUWB 2PNAA 2CRHA 2EKXA 3VRZA 1LKLA 2RVFA 4L1BB 3IN7A 4GPLB 4F5AA 1GRIA 3S9KA 2CI8A 1OO4A 1TZEE 1A1EA 4A4CA 1M61A 4ROJA 2RMXA 3S8NA 1M27A 4WWQA 1A1CA 1B47A 2QMSA 1SHBA 1YVHA 1A07A 1O4OA 4GWFA 1AYCA 2CI9A 2EOBA 5D0JA 3HHMB 2C9WA 1OO3A 3PJPA 1FHSA 1O4DA 2L6KA 3UYOA 1CWDL 1O4HA 3GXWA 3MXYA 1FYRA 2EL8A 3PLFB 5DC4A 2L3TA 2CS0A 2IZVA 2KK6A 2L4KA 2MK2A 1FU5A 1OPKA 2DM0A 4XZ1A 2Y1MA 1BHFA 1UURA 2LCTA 4FBNA 3VS1A 1X6CA 2PLEA 1AOUF 1K9AA 1O4EA 5IBMA 2PLDA 2AOBA 2AUGA 2MRKA 3IMJA 5GJHA 1IJRA 5HKWA 3KFJA 2RORA 5DC0B 2SRCA 2PTKA 4H1OA 1O4GA 2ABLA 3BKBA 1OPLA 2DX0A 1D4TA 5BO4A 1BKMA 2FO0A 1FMKA 2ECDA 3TKZA 3N84A 4A4BA 5DF6A 1QCFA 4LUDA 3IMDA 3OB1B 3VRRA 2LQWA 3VS7A 4GL9E 3BUOB 2IUGA 2B3OA 1O41A 2MQIA 3UF4A 3BUNB 1Y1UA 1BMBA 2EO3A 1MW4A 1BFIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O4M A;  3MAZ A;  4FL2 A;  4OHL A;  1O44 A;  3VS3 A;  2GSB A;  1CWE A;  4K44 A;  3PSJ A;  3VGO A;  2LNX A;  1O42 A;  1R1P A;  3EAZ A;  2RSY A;  1SPS A;  3S8L A;  1QG1 E;  2YSX A;  1O4K A;  4QSY A;  1R1Q A;  4TZI A;  4K2R A;  2EU0 A;  1O4P A;  1A08 A;  1LUN A;  2H8H A;  1MIL A;  1O48 A;  1JYR A;  2IUH A;  5EHR A;  4U17 A;  2EYV A;  1UUS A;  2HDV A;  1BM2 A;  1G83 A;  3HCK A;  2VIF A;  3PSK A;  1JWO A;  1ZFP E;  4JEG A;  2IUI A;  2DLY A;  2LQN A;  3CD3 A;  5KAZ A;  1A1A A;  4XZ0 A;  1BLJ A;  4NWF A;  2JYQ A;  3GXX A;  1O4F A;  1O4I A;  2HCK A;  4M4Z A;  5I6V A;  5EG3 B;  1R1S A;  3QWY A;  5EEL A;  1LKK A;  3PQZ A;  4K11 A;  1BF5 A;  1KC2 A;  3PFV A;  1BG1 A;  1BLK A;  3PS5 A;  1WQU A;  1JYU A;  4D8K A;  3HIZ B;  1AYB A;  3ZNI A;  1A09 A;  3M7F A;  2K7A B;  1D1Z A;  2HDX A;  2H46 E;  3VS4 A;  1AYA A;  3OB2 B;  1O4A A;  2MRJ A;  4F59 A;  1HCT B;  1O43 A;  1LUI A;  2EYZ A;  4DGX A;  1NZV A;  3BUM B;  2C0O A;  2HMH A;  4FL3 A;  1H9O A;  1NZL A;  2OZO A;  3QWX X;  1A1B A;  1A81 A;  3VRP A;  2BBU A;  1LUK A;  3IN8 A;  3MXC A;  4H34 A;  1PIC A;  1Y57 A;  5EHP A;  1HCS B;  1I3Z A;  3TL0 A;  1SHD A;  2YU7 A;  1CJ1 A;  1SHA A;  1X0N A;  4LUE A;  1LCK A;  1X27 A;  5DC9 A;  3CXL A;  3GQI B;  4OHI A;  2OQ1 A;  1O4Q A;  3US4 A;  1BFJ A;  2HUW A;  1BHH B;  2C0T A;  3BUX B;  2C0I A;  1NRV A;  1FBV A;  3VS6 A;  1YVL A;  2H5K A;  2Y3A B;  4JGH A;  4P9Z A;  1KA6 A;  2MC1 A;  2DLZ A;  1O45 A;  2SHP A;  1XA6 A;  1SPR A;  3N7Y A;  4X6S A;  3VS2 A;  5AXI A;  4NWG A;  1O4B A;  5AUL A;  5EEQ A;  1BHH A;  1F1W A;  1O47 A;  1O4C A;  3OP0 A;  1RQQ C;  2CBL A;  1CSZ A;  3WA4 A;  1O46 A;  1O4R A;  1CSY A;  2DCR A;  5J3X A;  1RJA A;  2CR4 A;  2ETZ A;  3CBL A;  3OVE A;  1Z3K A;  4OHH A;  5HKZ A;  4EIH A;  3VRN A;  1O49 A;  1KSW A;  1FU6 A;  3S8O A;  3EAC A;  2LNW A;  5IBS A;  5CDW A;  4K45 A;  5GJI A;  1SKJ A;  1JYQ A;  1RPY A;  4E68 A;  1BKL A;  4OHD A;  1O4J A;  1P13 A;  2EO6 A;  3VRQ A;  1AYD A;  2AOA A;  2CIA A;  1F2F A;  3K2M A;  4E93 A;  3VS5 A;  2GE9 A;  2KNO A;  3VRY A;  4DGP A;  1IS0 A;  1FBZ A;  3T04 A;  1LUM A;  3N8M A;  4F5B A;  1O4N A;  3OV1 A;  4OHE A;  2FCI A;  1AOT F;  4U1P A;  1D4W A;  1TCE A;  1O4L A;  1QAD A;  3C7I A;  1AB2 A;  1KA7 A;  3VS0 A;  3CWG A;  5HKY A;  1GHU A;  2K79 B;  2PNB A;  2DVJ A;  1AD5 A;  4P9V A;  2Y1N A;  2EYY A;  2XP1 A;  3VRO A;  3NHN A;  1LCJ A;  4EY0 A;  1JU5 A;  4JE4 A;  3BUW B;  2PNA A;  2CRH A;  2EKX A;  3VRZ A;  1LKL A;  2RVF A;  4L1B B;  3IN7 A;  4GPL B;  4F5A A;  1GRI A;  3S9K A;  2CI8 A;  1OO4 A;  1TZE E;  1A1E A;  4A4C A;  1M61 A;  4ROJ A;  2RMX A;  3S8N A;  1M27 A;  4WWQ A;  1A1C A;  1B47 A;  2QMS A;  1SHB A;  1YVH A;  1A07 A;  1O4O A;  4GWF A;  1AYC A;  2CI9 A;  2EOB A;  5D0J A;  3HHM B;  2C9W A;  1OO3 A;  3PJP A;  1FHS A;  1O4D A;  2L6K A;  3UYO A;  1CWD L;  1O4H A;  3GXW A;  3MXY A;  1FYR A;  2EL8 A;  3PLF B;  5DC4 A;  2L3T A;  2CS0 A;  2IZV A;  2KK6 A;  2L4K A;  2MK2 A;  1FU5 A;  1OPK A;  2DM0 A;  4XZ1 A;  2Y1M A;  1BHF A;  1UUR A;  2LCT A;  4FBN A;  3VS1 A;  1X6C A;  2PLE A;  1AOU F;  1K9A A;  1O4E A;  5IBM A;  2PLD A;  2AOB A;  2AUG A;  2MRK A;  3IMJ A;  5GJH A;  1IJR A;  5HKW A;  3KFJ A;  2ROR A;  5DC0 B;  2SRC A;  2PTK A;  4H1O A;  1O4G A;  2ABL A;  3BKB A;  1OPL A;  2DX0 A;  1D4T A;  5BO4 A;  1BKM A;  2FO0 A;  1FMK A;  2ECD A;  3TKZ A;  3N84 A;  4A4B A;  5DF6 A;  1QCF A;  4LUD A;  3IMD A;  3OB1 B;  3VRR A;  2LQW A;  3VS7 A;  4GL9 E;  3BUO B;  2IUG A;  2B3O A;  1O41 A;  2MQI A;  3UF4 A;  3BUN B;  1Y1U A;  1BMB A;  2EO3 A;  1MW4 A;  1BFI A; 
#chains in the Genus database with same CATH topology
 1O4M A;  3MAZ A;  4FL2 A;  4OHL A;  1O44 A;  3VS3 A;  2GSB A;  1CWE A;  4K44 A;  3PSJ A;  3VGO A;  2LNX A;  1O42 A;  1R1P A;  3EAZ A;  2RSY A;  1SPS A;  3S8L A;  1QG1 E;  2YSX A;  1O4K A;  4QSY A;  1R1Q A;  4TZI A;  4K2R A;  2EU0 A;  1O4P A;  1A08 A;  1LUN A;  2H8H A;  1MIL A;  1O48 A;  1JYR A;  2IUH A;  5EHR A;  4U17 A;  2EYV A;  1UUS A;  2HDV A;  1BM2 A;  1G83 A;  3HCK A;  2VIF A;  3PSK A;  1JWO A;  1ZFP E;  4JEG A;  2IUI A;  2DLY A;  2LQN A;  3CD3 A;  5KAZ A;  1A1A A;  4XZ0 A;  1BLJ A;  4NWF A;  2JYQ A;  3GXX A;  1O4F A;  1O4I A;  2HCK A;  4M4Z A;  5I6V A;  5EG3 B;  1R1S A;  3QWY A;  5EEL A;  1LKK A;  3PQZ A;  4K11 A;  1BF5 A;  1KC2 A;  3PFV A;  1BG1 A;  1BLK A;  3PS5 A;  1WQU A;  1JYU A;  4D8K A;  3HIZ B;  1AYB A;  3ZNI A;  1A09 A;  3M7F A;  2K7A B;  1D1Z A;  2HDX A;  2H46 E;  3VS4 A;  1AYA A;  3OB2 B;  1O4A A;  2MRJ A;  4F59 A;  1HCT B;  1O43 A;  1LUI A;  2EYZ A;  4DGX A;  1NZV A;  3BUM B;  2C0O A;  2HMH A;  4FL3 A;  1H9O A;  1NZL A;  2OZO A;  3QWX X;  1A1B A;  1A81 A;  3VRP A;  2BBU A;  1LUK A;  3IN8 A;  3MXC A;  4H34 A;  1PIC A;  1Y57 A;  5EHP A;  1HCS B;  1I3Z A;  3TL0 A;  1SHD A;  2YU7 A;  1CJ1 A;  1SHA A;  1X0N A;  4LUE A;  1LCK A;  1X27 A;  5DC9 A;  3CXL A;  3GQI B;  4OHI A;  2OQ1 A;  1O4Q A;  3US4 A;  1BFJ A;  2HUW A;  1BHH B;  2C0T A;  3BUX B;  2C0I A;  1NRV A;  3K2T A;  2KGY A;  1FBV A;  3VS6 A;  1YVL A;  2H5K A;  2Y3A B;  4JGH A;  4P9Z A;  1KA6 A;  2MC1 A;  2DLZ A;  1O45 A;  2SHP A;  1XA6 A;  1SPR A;  3N7Y A;  4X6S A;  3VS2 A;  5AXI A;  4NWG A;  1O4B A;  5AUL A;  5EEQ A;  1BHH A;  1F1W A;  1O47 A;  1O4C A;  3OP0 A;  1RQQ C;  2CBL A;  1CSZ A;  3WA4 A;  1O46 A;  1O4R A;  1CSY A;  2DCR A;  5J3X A;  1RJA A;  2CR4 A;  2ETZ A;  3CBL A;  3OVE A;  1Z3K A;  4OHH A;  5HKZ A;  4EIH A;  3VRN A;  1O49 A;  1KSW A;  1FU6 A;  3S8O A;  3EAC A;  2LNW A;  5IBS A;  5CDW A;  4K45 A;  5GJI A;  1SKJ A;  1JYQ A;  1RPY A;  4E68 A;  1BKL A;  4OHD A;  1O4J A;  1P13 A;  2EO6 A;  3VRQ A;  1AYD A;  2AOA A;  2CIA A;  1F2F A;  3K2M A;  4E93 A;  3VS5 A;  2GE9 A;  2KNO A;  3VRY A;  4DGP A;  1IS0 A;  1FBZ A;  3T04 A;  1LUM A;  3N8M A;  4F5B A;  1O4N A;  3OV1 A;  4OHE A;  2FCI A;  1AOT F;  4U1P A;  1D4W A;  1TCE A;  1O4L A;  1QAD A;  3C7I A;  1AB2 A;  1KA7 A;  3VS0 A;  3CWG A;  5HKY A;  1GHU A;  2K79 B;  2PNB A;  2DVJ A;  1AD5 A;  4P9V A;  2Y1N A;  2EYY A;  2XP1 A;  3VRO A;  3NHN A;  1LCJ A;  4EY0 A;  1JU5 A;  4JE4 A;  3BUW B;  2PNA A;  2LRA A;  2CRH A;  2EKX A;  3VRZ A;  1LKL A;  2RVF A;  4L1B B;  3IN7 A;  4GPL B;  4F5A A;  1GRI A;  3S9K A;  2CI8 A;  1OO4 A;  1TZE E;  1A1E A;  4A4C A;  1M61 A;  4ROJ A;  2RMX A;  3S8N A;  1M27 A;  4WWQ A;  1A1C A;  1B47 A;  2QMS A;  1SHB A;  1YVH A;  1A07 A;  1O4O A;  4GWF A;  1AYC A;  2CI9 A;  2EOB A;  5D0J A;  3HHM B;  2C9W A;  1OO3 A;  3PJP A;  1FHS A;  1O4D A;  2L6K A;  3UYO A;  1CWD L;  1O4H A;  3GXW A;  3MXY A;  1FYR A;  2EL8 A;  3PLF B;  5DC4 A;  2L3T A;  2CS0 A;  2IZV A;  2KK6 A;  2L4K A;  2MK2 A;  1FU5 A;  1OPK A;  2DM0 A;  4XZ1 A;  2Y1M A;  1BHF A;  1UUR A;  2LCT A;  4FBN A;  3VS1 A;  1X6C A;  2PLE A;  1AOU F;  1K9A A;  1O4E A;  5IBM A;  2PLD A;  2AOB A;  2AUG A;  2MRK A;  3IMJ A;  5GJH A;  1IJR A;  5HKW A;  3KFJ A;  2ROR A;  5DC0 B;  2SRC A;  2PTK A;  4H1O A;  1O4G A;  2ABL A;  3BKB A;  1OPL A;  2DX0 A;  1D4T A;  5BO4 A;  1BKM A;  2FO0 A;  1FMK A;  2ECD A;  3TKZ A;  3N84 A;  4A4B A;  5DF6 A;  1QCF A;  4LUD A;  3IMD A;  3OB1 B;  3VRR A;  2LQW A;  3VS7 A;  4GL9 E;  3BUO B;  2IUG A;  2B3O A;  3LYV A;  1O41 A;  2MQI A;  3UF4 A;  3BUN B;  1Y1U A;  1BMB A;  2EO3 A;  1MW4 A;  1BFI A; 
#chains in the Genus database with same CATH homology
 1O4M A;  3MAZ A;  4FL2 A;  4OHL A;  1O44 A;  3VS3 A;  2GSB A;  1CWE A;  4K44 A;  3PSJ A;  3VGO A;  2LNX A;  1O42 A;  1R1P A;  3EAZ A;  2RSY A;  1SPS A;  3S8L A;  1QG1 E;  2YSX A;  1O4K A;  4QSY A;  1R1Q A;  4TZI A;  4K2R A;  2EU0 A;  1O4P A;  1A08 A;  1LUN A;  2H8H A;  1MIL A;  1O48 A;  1JYR A;  2IUH A;  5EHR A;  4U17 A;  2EYV A;  1UUS A;  2HDV A;  1BM2 A;  1G83 A;  3HCK A;  2VIF A;  3PSK A;  1JWO A;  1ZFP E;  4JEG A;  2IUI A;  2DLY A;  2LQN A;  3CD3 A;  5KAZ A;  1A1A A;  4XZ0 A;  1BLJ A;  4NWF A;  2JYQ A;  3GXX A;  1O4F A;  1O4I A;  2HCK A;  4M4Z A;  5I6V A;  5EG3 B;  1R1S A;  3QWY A;  5EEL A;  1LKK A;  3PQZ A;  4K11 A;  1BF5 A;  1KC2 A;  3PFV A;  1BG1 A;  1BLK A;  3PS5 A;  1WQU A;  1JYU A;  4D8K A;  3HIZ B;  1AYB A;  3ZNI A;  1A09 A;  3M7F A;  2K7A B;  1D1Z A;  2HDX A;  2H46 E;  3VS4 A;  1AYA A;  3OB2 B;  1O4A A;  2MRJ A;  4F59 A;  1HCT B;  1O43 A;  1LUI A;  2EYZ A;  4DGX A;  1NZV A;  3BUM B;  2C0O A;  2HMH A;  4FL3 A;  1H9O A;  1NZL A;  2OZO A;  3QWX X;  1A1B A;  1A81 A;  3VRP A;  2BBU A;  1LUK A;  3IN8 A;  3MXC A;  4H34 A;  1PIC A;  1Y57 A;  5EHP A;  1HCS B;  1I3Z A;  3TL0 A;  1SHD A;  2YU7 A;  1CJ1 A;  1SHA A;  1X0N A;  4LUE A;  1LCK A;  1X27 A;  5DC9 A;  3CXL A;  3GQI B;  4OHI A;  2OQ1 A;  1O4Q A;  3US4 A;  1BFJ A;  2HUW A;  1BHH B;  2C0T A;  3BUX B;  2C0I A;  1NRV A;  1FBV A;  3VS6 A;  1YVL A;  2H5K A;  2Y3A B;  4JGH A;  4P9Z A;  1KA6 A;  2MC1 A;  2DLZ A;  1O45 A;  2SHP A;  1XA6 A;  1SPR A;  3N7Y A;  4X6S A;  3VS2 A;  5AXI A;  4NWG A;  1O4B A;  5AUL A;  5EEQ A;  1BHH A;  1F1W A;  1O47 A;  1O4C A;  3OP0 A;  1RQQ C;  2CBL A;  1CSZ A;  3WA4 A;  1O46 A;  1O4R A;  1CSY A;  2DCR A;  5J3X A;  1RJA A;  2CR4 A;  2ETZ A;  3CBL A;  3OVE A;  1Z3K A;  4OHH A;  5HKZ A;  4EIH A;  3VRN A;  1O49 A;  1KSW A;  1FU6 A;  3S8O A;  3EAC A;  2LNW A;  5IBS A;  5CDW A;  4K45 A;  5GJI A;  1SKJ A;  1JYQ A;  1RPY A;  4E68 A;  1BKL A;  4OHD A;  1O4J A;  1P13 A;  2EO6 A;  3VRQ A;  1AYD A;  2AOA A;  2CIA A;  1F2F A;  3K2M A;  4E93 A;  3VS5 A;  2GE9 A;  2KNO A;  3VRY A;  4DGP A;  1IS0 A;  1FBZ A;  3T04 A;  1LUM A;  3N8M A;  4F5B A;  1O4N A;  3OV1 A;  4OHE A;  2FCI A;  1AOT F;  4U1P A;  1D4W A;  1TCE A;  1O4L A;  1QAD A;  3C7I A;  1AB2 A;  1KA7 A;  3VS0 A;  3CWG A;  5HKY A;  1GHU A;  2K79 B;  2PNB A;  2DVJ A;  1AD5 A;  4P9V A;  2Y1N A;  2EYY A;  2XP1 A;  3VRO A;  3NHN A;  1LCJ A;  4EY0 A;  1JU5 A;  4JE4 A;  3BUW B;  2PNA A;  2CRH A;  2EKX A;  3VRZ A;  1LKL A;  2RVF A;  4L1B B;  3IN7 A;  4GPL B;  4F5A A;  1GRI A;  3S9K A;  2CI8 A;  1OO4 A;  1TZE E;  1A1E A;  4A4C A;  1M61 A;  4ROJ A;  2RMX A;  3S8N A;  1M27 A;  4WWQ A;  1A1C A;  1B47 A;  2QMS A;  1SHB A;  1YVH A;  1A07 A;  1O4O A;  4GWF A;  1AYC A;  2CI9 A;  2EOB A;  5D0J A;  3HHM B;  2C9W A;  1OO3 A;  3PJP A;  1FHS A;  1O4D A;  2L6K A;  3UYO A;  1CWD L;  1O4H A;  3GXW A;  3MXY A;  1FYR A;  2EL8 A;  3PLF B;  5DC4 A;  2L3T A;  2CS0 A;  2IZV A;  2KK6 A;  2L4K A;  2MK2 A;  1FU5 A;  1OPK A;  2DM0 A;  4XZ1 A;  2Y1M A;  1BHF A;  1UUR A;  2LCT A;  4FBN A;  3VS1 A;  1X6C A;  2PLE A;  1AOU F;  1K9A A;  1O4E A;  5IBM A;  2PLD A;  2AOB A;  2AUG A;  2MRK A;  3IMJ A;  5GJH A;  1IJR A;  5HKW A;  3KFJ A;  2ROR A;  5DC0 B;  2SRC A;  2PTK A;  4H1O A;  1O4G A;  2ABL A;  3BKB A;  1OPL A;  2DX0 A;  1D4T A;  5BO4 A;  1BKM A;  2FO0 A;  1FMK A;  2ECD A;  3TKZ A;  3N84 A;  4A4B A;  5DF6 A;  1QCF A;  4LUD A;  3IMD A;  3OB1 B;  3VRR A;  2LQW A;  3VS7 A;  4GL9 E;  3BUO B;  2IUG A;  2B3O A;  1O41 A;  2MQI A;  3UF4 A;  3BUN B;  1Y1U A;  1BMB A;  2EO3 A;  1MW4 A;  1BFI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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