4WWQA

Apo structure of the grb7 sh2 domain
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
112
structure length
112
Chain Sequence
LSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
publication title Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 7
total genus 29
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-11-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 4wwqA00
2AUGA 3NHNA 1JU5A 2Y1MA 2ABLA 3VS0A 1BHHB 1ZFPE 2PTKA 1TZEE 2MRJA 1TCEA 2DX0A 1LKKA 1WQUA 4K2RA 5KAZA 2CIAA 2SHPA 5GJHA 1O4OA 4FBNA 4ROJA 3VS1A 2LNXA 5DF6A 2GE9A 2H5KA 4LUEA 5HKZA 4K11A 1HCSB 3CXLA 1AOTF 1BLKA 3K2MA 3S8NA 3PFVA 2LCTA 1O49A 1YVHA 1FU6A 3IMJA 4A4BA 1MW4A 2YU7A 1X27A 1FBZA 3VGOA 5AXIA 1RJAA 1M27A 4NWGA 1BHFA 2C0TA 4D8KA 5DC4A 1KC2A 3WA4A 1O46A 5IBMA 3VROA 3BUWB 1LUNA 1O4IA 1A09A 3CBLA 4OHLA 4NWFA 2AOAA 2RMXA 1X6CA 1FMKA 5DC0B 2OQ1A 1O4BA 1OO3A 1IJRA 2H8HA 2EL8A 4DGXA 2RORA 2KNOA 3S9KA 3VRRA 1BHHA 3KFJA 1I3ZA 3TL0A 4GWFA 2RSYA 3MAZA 4JGHA 3S8LA 5EELA 1FU5A 3HCKA 3IN8A 1F1WA 4H1OA 1SHDA 1BKMA 4XZ0A 3US4A 1O48A 1OO4A 1O4LA 2OZOA 1O4GA 2VIFA 2DLZA 3OB2B 4LUDA 1MILA 4U17A 1A1BA 2EO6A 1QADA 1O45A 1BLJA 1LCJA 4F5BA 2CI8A 1JYRA 5DC9A 1O4HA 1O41A 1UUSA 3IMDA 1AYAA 1KA6A 2LQWA 1BFIA 3VRZA 2RVFA 1R1PA 1SPSA 2DCRA 1A81A 1KSWA 1CWDL 5BO4A 1D4WA 2CR4A 1O4JA 3VRNA 2H46E 4XZ1A 2HMHA 2CI9A 1AD5A 1K9AA 2Y3AB 3PLFB 1O4QA 1JWOA 2L6KA 1GRIA 1PICA 3BUNB 4E68A 2EYZA 1FHSA 2KK6A 1FYRA 2HCKA 3PSKA 1CJ1A 1JYQA 1M61A 2EOBA 1JYUA 2EO3A 2MK2A 2K79B 3MXYA 3BUXB 3VRQA 4K45A 5EG3B 1LUMA 1OPLA 5EHRA 1R1QA 1RQQC 2C0OA 2C0IA 2EYYA 5EEQA 5I6VA 2Y1NA 1O4PA 1UURA 1O4DA 1R1SA 4FL2A 3T04A 3BUMB 2PLEA 1KA7A 4A4CA 1AYCA 2CS0A 1O4EA 1A1AA 2JYQA 3BUOB 2L4KA 1GHUA 1O4KA 2FO0A 1QG1E 1AYBA 1O47A 3PQZA 1YVLA 1BMBA 1BKLA 2CBLA 1A07A 4EIHA 4K44A 1NZVA 1IS0A 5D0JA 1NRVA 5EHPA 5HKWA 1LKLA 3PS5A 1NZLA 2EYVA 3IN7A 1CSYA 1A08A 3GXXA 2PNBA 2YSXA 4OHDA 2IZVA 3C7IA 2PLDA 3UF4A 2HDVA 4M4ZA 4QSYA 2MC1A 4TZIA 4WWQA 1O43A 2K7AB 1AOUF 2AOBA 4OHEA 2GSBA 3N7YA 3VS5A 3VS2A 2DVJA 1QCFA 2CRHA 2EU0A 3VRYA 3OVEA 3HIZB 3MXCA 2LNWA 4U1PA 2ECDA 3EACA 1D1ZA 1H9OA 1BG1A 1O4RA 3TKZA 3M7FA 3GQIB 1AYDA 1O4MA 1SKJA 2PNAA 4JE4A 1Y57A 5AULA 4P9ZA 4X6SA 1O4AA 1SHBA 2BBUA 3VS3A 4FL3A 2C9WA 2IUIA 2ETZA 2SRCA 3OB1B 3BKBA 3UYOA 2EKXA 3EAZA 2DM0A 2QMSA 3QWXX 1AB2A 1F2FA 2DLYA 4H34A 3OP0A 1BFJA 1X0NA 3S8OA 3N8MA 3CWGA 1Y1UA 3HHMB 2XP1A 3QWYA 1B47A 3OV1A 2B3OA 2HUWA 4EY0A 1A1EA 1O4NA 4JEGA 1RPYA 1G83A 5J3XA 1CWEA 4OHHA 2LQNA 4E93A 5IBSA 4GL9E 2MRKA 4OHIA 3ZNIA 4P9VA 4F59A 1BF5A 1O4CA 3VS6A 1D4TA 1XA6A 1FBVA 3CD3A 3PSJA 1HCTB 1Z3KA 4L1BB 1LUKA 1BM2A 1OPKA 1O4FA 1CSZA 5CDWA 1SPRA 1SHAA 2MQIA 2L3TA 5HKYA 1P13A 4F5AA 2IUGA 3GXWA 1O44A 5GJIA 2HDXA 2IUHA 3PJPA 1A1CA 3VRPA 3VS4A 4GPLB 4DGPA 2FCIA 3N84A 1O42A 3VS7A 1LUIA 1LCKA
chains in the Genus database with same CATH superfamily
2AUGA 3NHNA 1JU5A 2Y1MA 2ABLA 3VS0A 1BHHB 1ZFPE 2PTKA 1TZEE 2MRJA 1TCEA 2DX0A 1LKKA 1WQUA 4K2RA 5KAZA 2CIAA 2SHPA 5GJHA 1O4OA 4FBNA 4ROJA 3VS1A 2LNXA 5DF6A 2GE9A 2H5KA 4LUEA 5HKZA 4K11A 1HCSB 3CXLA 1AOTF 1BLKA 3K2MA 3S8NA 3PFVA 2LCTA 1O49A 1YVHA 1FU6A 3IMJA 4A4BA 1MW4A 2YU7A 1X27A 1FBZA 3VGOA 5AXIA 1RJAA 1M27A 4NWGA 1BHFA 2C0TA 4D8KA 5DC4A 1KC2A 3WA4A 1O46A 5IBMA 3VROA 3BUWB 1LUNA 1O4IA 1A09A 3CBLA 4OHLA 4NWFA 2AOAA 2RMXA 1X6CA 1FMKA 2KGYA 5DC0B 2OQ1A 1O4BA 1OO3A 1IJRA 2H8HA 2EL8A 4DGXA 2RORA 2KNOA 3S9KA 3VRRA 1BHHA 3KFJA 1I3ZA 3TL0A 4GWFA 2RSYA 3MAZA 4JGHA 3S8LA 5EELA 1FU5A 3HCKA 3IN8A 1F1WA 4H1OA 1SHDA 1BKMA 4XZ0A 3US4A 1O48A 1OO4A 1O4LA 2OZOA 1O4GA 2VIFA 2DLZA 3OB2B 4LUDA 1MILA 4U17A 1A1BA 2EO6A 1QADA 1O45A 1BLJA 1LCJA 4F5BA 2CI8A 1JYRA 5DC9A 1O4HA 1O41A 1UUSA 3IMDA 1AYAA 1KA6A 2LQWA 1BFIA 3VRZA 2RVFA 1R1PA 1SPSA 2DCRA 1A81A 1KSWA 1CWDL 5BO4A 1D4WA 2CR4A 1O4JA 3VRNA 2H46E 4XZ1A 2HMHA 2CI9A 1AD5A 1K9AA 2Y3AB 3PLFB 1O4QA 1JWOA 2L6KA 1GRIA 1PICA 3BUNB 4E68A 2EYZA 1FHSA 2KK6A 1FYRA 2HCKA 3PSKA 1CJ1A 1JYQA 1M61A 2EOBA 1JYUA 2EO3A 2MK2A 2K79B 3MXYA 3BUXB 3VRQA 4K45A 5EG3B 1LUMA 1OPLA 5EHRA 1R1QA 1RQQC 2C0OA 2C0IA 2EYYA 5EEQA 5I6VA 2Y1NA 1O4PA 1UURA 1O4DA 1R1SA 4FL2A 3T04A 3BUMB 2PLEA 1KA7A 3LYVA 4A4CA 1AYCA 2CS0A 1O4EA 1A1AA 2JYQA 3BUOB 2L4KA 1GHUA 1O4KA 2FO0A 1QG1E 1AYBA 1O47A 3PQZA 1YVLA 1BMBA 1BKLA 2CBLA 1A07A 4EIHA 4K44A 1NZVA 1IS0A 2LRAA 5D0JA 1NRVA 5EHPA 5HKWA 1LKLA 3PS5A 1NZLA 2EYVA 3IN7A 1CSYA 1A08A 3GXXA 2PNBA 2YSXA 4OHDA 2IZVA 3C7IA 2PLDA 3UF4A 2HDVA 4M4ZA 4QSYA 2MC1A 4TZIA 4WWQA 1O43A 2K7AB 1AOUF 2AOBA 4OHEA 2GSBA 3N7YA 3VS5A 3VS2A 2DVJA 1QCFA 2CRHA 2EU0A 3VRYA 3OVEA 3HIZB 3MXCA 2LNWA 4U1PA 2ECDA 3EACA 1D1ZA 1H9OA 1BG1A 1O4RA 3TKZA 3M7FA 3GQIB 1AYDA 1O4MA 1SKJA 2PNAA 4JE4A 1Y57A 5AULA 4P9ZA 4X6SA 1O4AA 1SHBA 2BBUA 3VS3A 4FL3A 3K2TA 2C9WA 2IUIA 2ETZA 2SRCA 3OB1B 3BKBA 3UYOA 2EKXA 3EAZA 2DM0A 2QMSA 3QWXX 1AB2A 1F2FA 2DLYA 4H34A 3OP0A 1BFJA 1X0NA 3S8OA 3N8MA 3CWGA 1Y1UA 3HHMB 2XP1A 3QWYA 1B47A 3OV1A 2B3OA 2HUWA 4EY0A 1A1EA 1O4NA 4JEGA 1RPYA 1G83A 5J3XA 1CWEA 4OHHA 2LQNA 4E93A 5IBSA 4GL9E 2MRKA 4OHIA 3ZNIA 4P9VA 4F59A 1BF5A 1O4CA 3VS6A 1D4TA 1XA6A 1FBVA 3CD3A 3PSJA 1HCTB 1Z3KA 4L1BB 1LUKA 1BM2A 1OPKA 1O4FA 1CSZA 5CDWA 1SPRA 1SHAA 2MQIA 2L3TA 5HKYA 1P13A 4F5AA 2IUGA 3GXWA 1O44A 5GJIA 2HDXA 2IUHA 3PJPA 1A1CA 3VRPA 3VS4A 4GPLB 4DGPA 2FCIA 3N84A 1O42A 3VS7A 1LUIA 1LCKA
chains in the Genus database with same CATH topology
2AUGA 3NHNA 1JU5A 2Y1MA 2ABLA 3VS0A 1BHHB 1ZFPE 2PTKA 1TZEE 2MRJA 1TCEA 2DX0A 1LKKA 1WQUA 4K2RA 5KAZA 2CIAA 2SHPA 5GJHA 1O4OA 4FBNA 4ROJA 3VS1A 2LNXA 5DF6A 2GE9A 2H5KA 4LUEA 5HKZA 4K11A 1HCSB 3CXLA 1AOTF 1BLKA 3K2MA 3S8NA 3PFVA 2LCTA 1O49A 1YVHA 1FU6A 3IMJA 4A4BA 1MW4A 2YU7A 1X27A 1FBZA 3VGOA 5AXIA 1RJAA 1M27A 4NWGA 1BHFA 2C0TA 4D8KA 5DC4A 1KC2A 3WA4A 1O46A 5IBMA 3VROA 3BUWB 1LUNA 1O4IA 1A09A 3CBLA 4OHLA 4NWFA 2AOAA 2RMXA 1X6CA 1FMKA 5DC0B 2OQ1A 1O4BA 1OO3A 1IJRA 2H8HA 2EL8A 4DGXA 2RORA 2KNOA 3S9KA 3VRRA 1BHHA 3KFJA 1I3ZA 3TL0A 4GWFA 2RSYA 3MAZA 4JGHA 3S8LA 5EELA 1FU5A 3HCKA 3IN8A 1F1WA 4H1OA 1SHDA 1BKMA 4XZ0A 3US4A 1O48A 1OO4A 1O4LA 2OZOA 1O4GA 2VIFA 2DLZA 3OB2B 4LUDA 1MILA 4U17A 1A1BA 2EO6A 1QADA 1O45A 1BLJA 1LCJA 4F5BA 2CI8A 1JYRA 5DC9A 1O4HA 1O41A 1UUSA 3IMDA 1AYAA 1KA6A 2LQWA 1BFIA 3VRZA 2RVFA 1R1PA 1SPSA 2DCRA 1A81A 1KSWA 1CWDL 5BO4A 1D4WA 2CR4A 1O4JA 3VRNA 2H46E 4XZ1A 2HMHA 2CI9A 1AD5A 1K9AA 2Y3AB 3PLFB 1O4QA 1JWOA 2L6KA 1GRIA 1PICA 3BUNB 4E68A 2EYZA 1FHSA 2KK6A 1FYRA 2HCKA 3PSKA 1CJ1A 1JYQA 1M61A 2EOBA 1JYUA 2EO3A 2MK2A 2K79B 3MXYA 3BUXB 3VRQA 4K45A 5EG3B 1LUMA 1OPLA 5EHRA 1R1QA 1RQQC 2C0OA 2C0IA 2EYYA 5EEQA 5I6VA 2Y1NA 1O4PA 1UURA 1O4DA 1R1SA 4FL2A 3T04A 3BUMB 2PLEA 1KA7A 4A4CA 1AYCA 2CS0A 1O4EA 1A1AA 2JYQA 3BUOB 2L4KA 1GHUA 1O4KA 2FO0A 1QG1E 1AYBA 1O47A 3PQZA 1YVLA 1BMBA 1BKLA 2CBLA 1A07A 4EIHA 4K44A 1NZVA 1IS0A 5D0JA 1NRVA 5EHPA 5HKWA 1LKLA 3PS5A 1NZLA 2EYVA 3IN7A 1CSYA 1A08A 3GXXA 2PNBA 2YSXA 4OHDA 2IZVA 3C7IA 2PLDA 3UF4A 2HDVA 4M4ZA 4QSYA 2MC1A 4TZIA 4WWQA 1O43A 2K7AB 1AOUF 2AOBA 4OHEA 2GSBA 3N7YA 3VS5A 3VS2A 2DVJA 1QCFA 2CRHA 2EU0A 3VRYA 3OVEA 3HIZB 3MXCA 2LNWA 4U1PA 2ECDA 3EACA 1D1ZA 1H9OA 1BG1A 1O4RA 3TKZA 3M7FA 3GQIB 1AYDA 1O4MA 1SKJA 2PNAA 4JE4A 1Y57A 5AULA 4P9ZA 4X6SA 1O4AA 1SHBA 2BBUA 3VS3A 4FL3A 2C9WA 2IUIA 2ETZA 2SRCA 3OB1B 3BKBA 3UYOA 2EKXA 3EAZA 2DM0A 2QMSA 3QWXX 1AB2A 1F2FA 2DLYA 4H34A 3OP0A 1BFJA 1X0NA 3S8OA 3N8MA 3CWGA 1Y1UA 3HHMB 2XP1A 3QWYA 1B47A 3OV1A 2B3OA 2HUWA 4EY0A 1A1EA 1O4NA 4JEGA 1RPYA 1G83A 5J3XA 1CWEA 4OHHA 2LQNA 4E93A 5IBSA 4GL9E 2MRKA 4OHIA 3ZNIA 4P9VA 4F59A 1BF5A 1O4CA 3VS6A 1D4TA 1XA6A 1FBVA 3CD3A 3PSJA 1HCTB 1Z3KA 4L1BB 1LUKA 1BM2A 1OPKA 1O4FA 1CSZA 5CDWA 1SPRA 1SHAA 2MQIA 2L3TA 5HKYA 1P13A 4F5AA 2IUGA 3GXWA 1O44A 5GJIA 2HDXA 2IUHA 3PJPA 1A1CA 3VRPA 3VS4A 4GPLB 4DGPA 2FCIA 3N84A 1O42A 3VS7A 1LUIA 1LCKA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2AUG A;  3NHN A;  1JU5 A;  2Y1M A;  2ABL A;  3VS0 A;  1BHH B;  1ZFP E;  2PTK A;  1TZE E;  2MRJ A;  1TCE A;  2DX0 A;  1LKK A;  1WQU A;  4K2R A;  5KAZ A;  2CIA A;  2SHP A;  5GJH A;  1O4O A;  4FBN A;  4ROJ A;  3VS1 A;  2LNX A;  5DF6 A;  2GE9 A;  2H5K A;  4LUE A;  5HKZ A;  4K11 A;  1HCS B;  3CXL A;  1AOT F;  1BLK A;  3K2M A;  3S8N A;  3PFV A;  2LCT A;  1O49 A;  1YVH A;  1FU6 A;  3IMJ A;  4A4B A;  1MW4 A;  2YU7 A;  1X27 A;  1FBZ A;  3VGO A;  5AXI A;  1RJA A;  1M27 A;  4NWG A;  1BHF A;  2C0T A;  4D8K A;  5DC4 A;  1KC2 A;  3WA4 A;  1O46 A;  5IBM A;  3VRO A;  3BUW B;  1LUN A;  1O4I A;  1A09 A;  3CBL A;  4OHL A;  4NWF A;  2AOA A;  2RMX A;  1X6C A;  1FMK A;  5DC0 B;  2OQ1 A;  1O4B A;  1OO3 A;  1IJR A;  2H8H A;  2EL8 A;  4DGX A;  2ROR A;  2KNO A;  3S9K A;  3VRR A;  1BHH A;  3KFJ A;  1I3Z A;  3TL0 A;  4GWF A;  2RSY A;  3MAZ A;  4JGH A;  3S8L A;  5EEL A;  1FU5 A;  3HCK A;  3IN8 A;  1F1W A;  4H1O A;  1SHD A;  1BKM A;  4XZ0 A;  3US4 A;  1O48 A;  1OO4 A;  1O4L A;  2OZO A;  1O4G A;  2VIF A;  2DLZ A;  3OB2 B;  4LUD A;  1MIL A;  4U17 A;  1A1B A;  2EO6 A;  1QAD A;  1O45 A;  1BLJ A;  1LCJ A;  4F5B A;  2CI8 A;  1JYR A;  5DC9 A;  1O4H A;  1O41 A;  1UUS A;  3IMD A;  1AYA A;  1KA6 A;  2LQW A;  1BFI A;  3VRZ A;  2RVF A;  1R1P A;  1SPS A;  2DCR A;  1A81 A;  1KSW A;  1CWD L;  5BO4 A;  1D4W A;  2CR4 A;  1O4J A;  3VRN A;  2H46 E;  4XZ1 A;  2HMH A;  2CI9 A;  1AD5 A;  1K9A A;  2Y3A B;  3PLF B;  1O4Q A;  1JWO A;  2L6K A;  1GRI A;  1PIC A;  3BUN B;  4E68 A;  2EYZ A;  1FHS A;  2KK6 A;  1FYR A;  2HCK A;  3PSK A;  1CJ1 A;  1JYQ A;  1M61 A;  2EOB A;  1JYU A;  2EO3 A;  2MK2 A;  2K79 B;  3MXY A;  3BUX B;  3VRQ A;  4K45 A;  5EG3 B;  1LUM A;  1OPL A;  5EHR A;  1R1Q A;  1RQQ C;  2C0O A;  2C0I A;  2EYY A;  5EEQ A;  5I6V A;  2Y1N A;  1O4P A;  1UUR A;  1O4D A;  1R1S A;  4FL2 A;  3T04 A;  3BUM B;  2PLE A;  1KA7 A;  4A4C A;  1AYC A;  2CS0 A;  1O4E A;  1A1A A;  2JYQ A;  3BUO B;  2L4K A;  1GHU A;  1O4K A;  2FO0 A;  1QG1 E;  1AYB A;  1O47 A;  3PQZ A;  1YVL A;  1BMB A;  1BKL A;  2CBL A;  1A07 A;  4EIH A;  4K44 A;  1NZV A;  1IS0 A;  5D0J A;  1NRV A;  5EHP A;  5HKW A;  1LKL A;  3PS5 A;  1NZL A;  2EYV A;  3IN7 A;  1CSY A;  1A08 A;  3GXX A;  2PNB A;  2YSX A;  4OHD A;  2IZV A;  3C7I A;  2PLD A;  3UF4 A;  2HDV A;  4M4Z A;  4QSY A;  2MC1 A;  4TZI A;  4WWQ A;  1O43 A;  2K7A B;  1AOU F;  2AOB A;  4OHE A;  2GSB A;  3N7Y A;  3VS5 A;  3VS2 A;  2DVJ A;  1QCF A;  2CRH A;  2EU0 A;  3VRY A;  3OVE A;  3HIZ B;  3MXC A;  2LNW A;  4U1P A;  2ECD A;  3EAC A;  1D1Z A;  1H9O A;  1BG1 A;  1O4R A;  3TKZ A;  3M7F A;  3GQI B;  1AYD A;  1O4M A;  1SKJ A;  2PNA A;  4JE4 A;  1Y57 A;  5AUL A;  4P9Z A;  4X6S A;  1O4A A;  1SHB A;  2BBU A;  3VS3 A;  4FL3 A;  2C9W A;  2IUI A;  2ETZ A;  2SRC A;  3OB1 B;  3BKB A;  3UYO A;  2EKX A;  3EAZ A;  2DM0 A;  2QMS A;  3QWX X;  1AB2 A;  1F2F A;  2DLY A;  4H34 A;  3OP0 A;  1BFJ A;  1X0N A;  3S8O A;  3N8M A;  3CWG A;  1Y1U A;  3HHM B;  2XP1 A;  3QWY A;  1B47 A;  3OV1 A;  2B3O A;  2HUW A;  4EY0 A;  1A1E A;  1O4N A;  4JEG A;  1RPY A;  1G83 A;  5J3X A;  1CWE A;  4OHH A;  2LQN A;  4E93 A;  5IBS A;  4GL9 E;  2MRK A;  4OHI A;  3ZNI A;  4P9V A;  4F59 A;  1BF5 A;  1O4C A;  3VS6 A;  1D4T A;  1XA6 A;  1FBV A;  3CD3 A;  3PSJ A;  1HCT B;  1Z3K A;  4L1B B;  1LUK A;  1BM2 A;  1OPK A;  1O4F A;  1CSZ A;  5CDW A;  1SPR A;  1SHA A;  2MQI A;  2L3T A;  5HKY A;  1P13 A;  4F5A A;  2IUG A;  3GXW A;  1O44 A;  5GJI A;  2HDX A;  2IUH A;  3PJP A;  1A1C A;  3VRP A;  3VS4 A;  4GPL B;  4DGP A;  2FCI A;  3N84 A;  1O42 A;  3VS7 A;  1LUI A;  1LCK A; 
#chains in the Genus database with same CATH topology
 2AUG A;  3NHN A;  1JU5 A;  2Y1M A;  2ABL A;  3VS0 A;  1BHH B;  1ZFP E;  2PTK A;  1TZE E;  2MRJ A;  1TCE A;  2DX0 A;  1LKK A;  1WQU A;  4K2R A;  5KAZ A;  2CIA A;  2SHP A;  5GJH A;  1O4O A;  4FBN A;  4ROJ A;  3VS1 A;  2LNX A;  5DF6 A;  2GE9 A;  2H5K A;  4LUE A;  5HKZ A;  4K11 A;  1HCS B;  3CXL A;  1AOT F;  1BLK A;  3K2M A;  3S8N A;  3PFV A;  2LCT A;  1O49 A;  1YVH A;  1FU6 A;  3IMJ A;  4A4B A;  1MW4 A;  2YU7 A;  1X27 A;  1FBZ A;  3VGO A;  5AXI A;  1RJA A;  1M27 A;  4NWG A;  1BHF A;  2C0T A;  4D8K A;  5DC4 A;  1KC2 A;  3WA4 A;  1O46 A;  5IBM A;  3VRO A;  3BUW B;  1LUN A;  1O4I A;  1A09 A;  3CBL A;  4OHL A;  4NWF A;  2AOA A;  2RMX A;  1X6C A;  1FMK A;  2KGY A;  5DC0 B;  2OQ1 A;  1O4B A;  1OO3 A;  1IJR A;  2H8H A;  2EL8 A;  4DGX A;  2ROR A;  2KNO A;  3S9K A;  3VRR A;  1BHH A;  3KFJ A;  1I3Z A;  3TL0 A;  4GWF A;  2RSY A;  3MAZ A;  4JGH A;  3S8L A;  5EEL A;  1FU5 A;  3HCK A;  3IN8 A;  1F1W A;  4H1O A;  1SHD A;  1BKM A;  4XZ0 A;  3US4 A;  1O48 A;  1OO4 A;  1O4L A;  2OZO A;  1O4G A;  2VIF A;  2DLZ A;  3OB2 B;  4LUD A;  1MIL A;  4U17 A;  1A1B A;  2EO6 A;  1QAD A;  1O45 A;  1BLJ A;  1LCJ A;  4F5B A;  2CI8 A;  1JYR A;  5DC9 A;  1O4H A;  1O41 A;  1UUS A;  3IMD A;  1AYA A;  1KA6 A;  2LQW A;  1BFI A;  3VRZ A;  2RVF A;  1R1P A;  1SPS A;  2DCR A;  1A81 A;  1KSW A;  1CWD L;  5BO4 A;  1D4W A;  2CR4 A;  1O4J A;  3VRN A;  2H46 E;  4XZ1 A;  2HMH A;  2CI9 A;  1AD5 A;  1K9A A;  2Y3A B;  3PLF B;  1O4Q A;  1JWO A;  2L6K A;  1GRI A;  1PIC A;  3BUN B;  4E68 A;  2EYZ A;  1FHS A;  2KK6 A;  1FYR A;  2HCK A;  3PSK A;  1CJ1 A;  1JYQ A;  1M61 A;  2EOB A;  1JYU A;  2EO3 A;  2MK2 A;  2K79 B;  3MXY A;  3BUX B;  3VRQ A;  4K45 A;  5EG3 B;  1LUM A;  1OPL A;  5EHR A;  1R1Q A;  1RQQ C;  2C0O A;  2C0I A;  2EYY A;  5EEQ A;  5I6V A;  2Y1N A;  1O4P A;  1UUR A;  1O4D A;  1R1S A;  4FL2 A;  3T04 A;  3BUM B;  2PLE A;  1KA7 A;  3LYV A;  4A4C A;  1AYC A;  2CS0 A;  1O4E A;  1A1A A;  2JYQ A;  3BUO B;  2L4K A;  1GHU A;  1O4K A;  2FO0 A;  1QG1 E;  1AYB A;  1O47 A;  3PQZ A;  1YVL A;  1BMB A;  1BKL A;  2CBL A;  1A07 A;  4EIH A;  4K44 A;  1NZV A;  1IS0 A;  2LRA A;  5D0J A;  1NRV A;  5EHP A;  5HKW A;  1LKL A;  3PS5 A;  1NZL A;  2EYV A;  3IN7 A;  1CSY A;  1A08 A;  3GXX A;  2PNB A;  2YSX A;  4OHD A;  2IZV A;  3C7I A;  2PLD A;  3UF4 A;  2HDV A;  4M4Z A;  4QSY A;  2MC1 A;  4TZI A;  4WWQ A;  1O43 A;  2K7A B;  1AOU F;  2AOB A;  4OHE A;  2GSB A;  3N7Y A;  3VS5 A;  3VS2 A;  2DVJ A;  1QCF A;  2CRH A;  2EU0 A;  3VRY A;  3OVE A;  3HIZ B;  3MXC A;  2LNW A;  4U1P A;  2ECD A;  3EAC A;  1D1Z A;  1H9O A;  1BG1 A;  1O4R A;  3TKZ A;  3M7F A;  3GQI B;  1AYD A;  1O4M A;  1SKJ A;  2PNA A;  4JE4 A;  1Y57 A;  5AUL A;  4P9Z A;  4X6S A;  1O4A A;  1SHB A;  2BBU A;  3VS3 A;  4FL3 A;  3K2T A;  2C9W A;  2IUI A;  2ETZ A;  2SRC A;  3OB1 B;  3BKB A;  3UYO A;  2EKX A;  3EAZ A;  2DM0 A;  2QMS A;  3QWX X;  1AB2 A;  1F2F A;  2DLY A;  4H34 A;  3OP0 A;  1BFJ A;  1X0N A;  3S8O A;  3N8M A;  3CWG A;  1Y1U A;  3HHM B;  2XP1 A;  3QWY A;  1B47 A;  3OV1 A;  2B3O A;  2HUW A;  4EY0 A;  1A1E A;  1O4N A;  4JEG A;  1RPY A;  1G83 A;  5J3X A;  1CWE A;  4OHH A;  2LQN A;  4E93 A;  5IBS A;  4GL9 E;  2MRK A;  4OHI A;  3ZNI A;  4P9V A;  4F59 A;  1BF5 A;  1O4C A;  3VS6 A;  1D4T A;  1XA6 A;  1FBV A;  3CD3 A;  3PSJ A;  1HCT B;  1Z3K A;  4L1B B;  1LUK A;  1BM2 A;  1OPK A;  1O4F A;  1CSZ A;  5CDW A;  1SPR A;  1SHA A;  2MQI A;  2L3T A;  5HKY A;  1P13 A;  4F5A A;  2IUG A;  3GXW A;  1O44 A;  5GJI A;  2HDX A;  2IUH A;  3PJP A;  1A1C A;  3VRP A;  3VS4 A;  4GPL B;  4DGP A;  2FCI A;  3N84 A;  1O42 A;  3VS7 A;  1LUI A;  1LCK A; 
#chains in the Genus database with same CATH homology
 2AUG A;  3NHN A;  1JU5 A;  2Y1M A;  2ABL A;  3VS0 A;  1BHH B;  1ZFP E;  2PTK A;  1TZE E;  2MRJ A;  1TCE A;  2DX0 A;  1LKK A;  1WQU A;  4K2R A;  5KAZ A;  2CIA A;  2SHP A;  5GJH A;  1O4O A;  4FBN A;  4ROJ A;  3VS1 A;  2LNX A;  5DF6 A;  2GE9 A;  2H5K A;  4LUE A;  5HKZ A;  4K11 A;  1HCS B;  3CXL A;  1AOT F;  1BLK A;  3K2M A;  3S8N A;  3PFV A;  2LCT A;  1O49 A;  1YVH A;  1FU6 A;  3IMJ A;  4A4B A;  1MW4 A;  2YU7 A;  1X27 A;  1FBZ A;  3VGO A;  5AXI A;  1RJA A;  1M27 A;  4NWG A;  1BHF A;  2C0T A;  4D8K A;  5DC4 A;  1KC2 A;  3WA4 A;  1O46 A;  5IBM A;  3VRO A;  3BUW B;  1LUN A;  1O4I A;  1A09 A;  3CBL A;  4OHL A;  4NWF A;  2AOA A;  2RMX A;  1X6C A;  1FMK A;  5DC0 B;  2OQ1 A;  1O4B A;  1OO3 A;  1IJR A;  2H8H A;  2EL8 A;  4DGX A;  2ROR A;  2KNO A;  3S9K A;  3VRR A;  1BHH A;  3KFJ A;  1I3Z A;  3TL0 A;  4GWF A;  2RSY A;  3MAZ A;  4JGH A;  3S8L A;  5EEL A;  1FU5 A;  3HCK A;  3IN8 A;  1F1W A;  4H1O A;  1SHD A;  1BKM A;  4XZ0 A;  3US4 A;  1O48 A;  1OO4 A;  1O4L A;  2OZO A;  1O4G A;  2VIF A;  2DLZ A;  3OB2 B;  4LUD A;  1MIL A;  4U17 A;  1A1B A;  2EO6 A;  1QAD A;  1O45 A;  1BLJ A;  1LCJ A;  4F5B A;  2CI8 A;  1JYR A;  5DC9 A;  1O4H A;  1O41 A;  1UUS A;  3IMD A;  1AYA A;  1KA6 A;  2LQW A;  1BFI A;  3VRZ A;  2RVF A;  1R1P A;  1SPS A;  2DCR A;  1A81 A;  1KSW A;  1CWD L;  5BO4 A;  1D4W A;  2CR4 A;  1O4J A;  3VRN A;  2H46 E;  4XZ1 A;  2HMH A;  2CI9 A;  1AD5 A;  1K9A A;  2Y3A B;  3PLF B;  1O4Q A;  1JWO A;  2L6K A;  1GRI A;  1PIC A;  3BUN B;  4E68 A;  2EYZ A;  1FHS A;  2KK6 A;  1FYR A;  2HCK A;  3PSK A;  1CJ1 A;  1JYQ A;  1M61 A;  2EOB A;  1JYU A;  2EO3 A;  2MK2 A;  2K79 B;  3MXY A;  3BUX B;  3VRQ A;  4K45 A;  5EG3 B;  1LUM A;  1OPL A;  5EHR A;  1R1Q A;  1RQQ C;  2C0O A;  2C0I A;  2EYY A;  5EEQ A;  5I6V A;  2Y1N A;  1O4P A;  1UUR A;  1O4D A;  1R1S A;  4FL2 A;  3T04 A;  3BUM B;  2PLE A;  1KA7 A;  4A4C A;  1AYC A;  2CS0 A;  1O4E A;  1A1A A;  2JYQ A;  3BUO B;  2L4K A;  1GHU A;  1O4K A;  2FO0 A;  1QG1 E;  1AYB A;  1O47 A;  3PQZ A;  1YVL A;  1BMB A;  1BKL A;  2CBL A;  1A07 A;  4EIH A;  4K44 A;  1NZV A;  1IS0 A;  5D0J A;  1NRV A;  5EHP A;  5HKW A;  1LKL A;  3PS5 A;  1NZL A;  2EYV A;  3IN7 A;  1CSY A;  1A08 A;  3GXX A;  2PNB A;  2YSX A;  4OHD A;  2IZV A;  3C7I A;  2PLD A;  3UF4 A;  2HDV A;  4M4Z A;  4QSY A;  2MC1 A;  4TZI A;  4WWQ A;  1O43 A;  2K7A B;  1AOU F;  2AOB A;  4OHE A;  2GSB A;  3N7Y A;  3VS5 A;  3VS2 A;  2DVJ A;  1QCF A;  2CRH A;  2EU0 A;  3VRY A;  3OVE A;  3HIZ B;  3MXC A;  2LNW A;  4U1P A;  2ECD A;  3EAC A;  1D1Z A;  1H9O A;  1BG1 A;  1O4R A;  3TKZ A;  3M7F A;  3GQI B;  1AYD A;  1O4M A;  1SKJ A;  2PNA A;  4JE4 A;  1Y57 A;  5AUL A;  4P9Z A;  4X6S A;  1O4A A;  1SHB A;  2BBU A;  3VS3 A;  4FL3 A;  2C9W A;  2IUI A;  2ETZ A;  2SRC A;  3OB1 B;  3BKB A;  3UYO A;  2EKX A;  3EAZ A;  2DM0 A;  2QMS A;  3QWX X;  1AB2 A;  1F2F A;  2DLY A;  4H34 A;  3OP0 A;  1BFJ A;  1X0N A;  3S8O A;  3N8M A;  3CWG A;  1Y1U A;  3HHM B;  2XP1 A;  3QWY A;  1B47 A;  3OV1 A;  2B3O A;  2HUW A;  4EY0 A;  1A1E A;  1O4N A;  4JEG A;  1RPY A;  1G83 A;  5J3X A;  1CWE A;  4OHH A;  2LQN A;  4E93 A;  5IBS A;  4GL9 E;  2MRK A;  4OHI A;  3ZNI A;  4P9V A;  4F59 A;  1BF5 A;  1O4C A;  3VS6 A;  1D4T A;  1XA6 A;  1FBV A;  3CD3 A;  3PSJ A;  1HCT B;  1Z3K A;  4L1B B;  1LUK A;  1BM2 A;  1OPK A;  1O4F A;  1CSZ A;  5CDW A;  1SPR A;  1SHA A;  2MQI A;  2L3T A;  5HKY A;  1P13 A;  4F5A A;  2IUG A;  3GXW A;  1O44 A;  5GJI A;  2HDX A;  2IUH A;  3PJP A;  1A1C A;  3VRP A;  3VS4 A;  4GPL B;  4DGP A;  2FCI A;  3N84 A;  1O42 A;  3VS7 A;  1LUI A;  1LCK A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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