5CDWA

Crystal structure analysis of a mutant grb2 sh2 domain (w121g) with a pyvnv peptide
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
98
structure length
98
Chain Sequence
KPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLGVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and biophysical investigation of the interaction of a mutant Grb2 SH2 domain (W121G) with its cognate phosphopeptide.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Growth factor receptor-bound protein 2
total genus 16
structure length 98
sequence length 98
chains with identical sequence B, C, E, G, H, K, L, O, P, U, V, Y, Z, c, d
ec nomenclature
pdb deposition date 2015-07-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5cdwA00
2VIFA 2LNWA 3M7FA 1KSWA 1O4EA 4QSYA 1JYRA 1ZFPE 2RMXA 2SHPA 3MXCA 3WA4A 5HKYA 2CS0A 2PLDA 3CD3A 3OP0A 4GWFA 1AB2A 3HIZB 1A09A 4K44A 5DF6A 2PLEA 1LCKA 1LCJA 3VS7A 1IJRA 1JYQA 1NZLA 1BF5A 3PJPA 2JYQA 3KFJA 1AYBA 1O45A 3CWGA 4P9VA 1BLKA 2BBUA 1FBZA 1FBVA 5IBSA 1M61A 3VRQA 4K2RA 4NWFA 1O4JA 2LQNA 1NRVA 4E93A 2AUGA 1O4CA 1OPLA 1IS0A 2GSBA 1SHDA 1AOTF 1O4OA 4OHLA 4F5BA 4EIHA 4ROJA 1O46A 1YVHA 1O49A 2IUHA 1WQUA 3VRNA 1X6CA 3T04A 3CXLA 3VS5A 2XP1A 1PICA 2EYVA 2GE9A 2IUGA 1R1PA 1JU5A 2IZVA 2DVJA 1O4AA 5D0JA 1SHAA 2CR4A 1GHUA 3N8MA 4U1PA 3VS3A 1LKLA 1RJAA 3MAZA 1MILA 5GJHA 1BHHB 2HDVA 1D4WA 3OB1B 3OVEA 2Y3AB 2DCRA 2DLYA 1SHBA 1O4HA 2DM0A 2ETZA 2MK2A 1MW4A 1LUMA 2RSYA 1AD5A 1O44A 2C9WA 2H46E 4DGPA 4K11A 1Y1UA 4E68A 4FL3A 3BUXB 2HMHA 2MRJA 4DGXA 2RVFA 3PSKA 5EG3B 1B47A 1A1AA 1O4MA 4TZIA 3OB2B 4H34A 2CBLA 1K9AA 1BLJA 3VS6A 1O4BA 5EHRA 3IN7A 1O4DA 1H9OA 3QWXX 2QMSA 2L6KA 2MC1A 2MRKA 2CI8A 3PQZA 1QCFA 3IN8A 1CSYA 3GXXA 1HCSB 1CWEA 3US4A 5KAZA 4GL9E 1JWOA 3N84A 5DC0B 1R1QA 4XZ1A 1O4KA 1HCTB 4JGHA 4FBNA 3UF4A 1CSZA 3GXWA 3BUNB 1A08A 2KNOA 1KA7A 4EY0A 4M4ZA 1GRIA 2CI9A 4LUEA 1BHHA 2CIAA 1LUKA 5EELA 3VROA 3S8OA 2EKXA 4A4BA 5DC4A 2L4KA 5J3XA 2EYZA 4U17A 2AOBA 3VRYA 2OQ1A 2LCTA 2SRCA 1RPYA 2KK6A 1F2FA 2FO0A 1QADA 3VS0A 4OHEA 1LKKA 3N7YA 1KA6A 2PNBA 1SPRA 2LQWA 1X0NA 2HCKA 3VGOA 1FMKA 1O41A 3QWYA 2C0TA 2L3TA 4A4CA 1O4LA 1OO3A 5HKWA 3VS2A 3NHNA 1G83A 2Y1NA 3BUMB 3TL0A 3C7IA 1UUSA 1BMBA 4F5AA 1BFIA 3BUOB 5EEQA 1SPSA 3VRPA 3VRZA 1A1EA 4GPLB 1AOUF 1O4IA 2RORA 1AYCA 1XA6A 2PNAA 3PSJA 3UYOA 1OPKA 1FYRA 1R1SA 3TKZA 4OHHA 2FCIA 1A1BA 1QG1E 1O42A 5DC9A 1JYUA 2HDXA 2Y1MA 1LUNA 3PS5A 3OV1A 3GQIB 5BO4A 2H8HA 1FU5A 1BM2A 1O48A 1X27A 2EL8A 3CBLA 1Z3KA 1BKLA 4F59A 2HUWA 1M27A 2EYYA 4XZ0A 5CDWA 2LNXA 1I3ZA 1O4NA 2YSXA 2DLZA 1P13A 1O4PA 4P9ZA 5AXIA 2K79B 1CWDL 2DX0A 5AULA 2C0IA 1A1CA 1YVLA 1SKJA 4H1OA 1BG1A 3S9KA 2AOAA 1Y57A 1O4RA 1NZVA 3BUWB 2YU7A 1A81A 2ECDA 3HHMB 3IMDA 1BHFA 1FHSA 1O4QA 5GJIA 1D1ZA 2MQIA 2C0OA 4X6SA 3ZNIA 1LUIA 3HCKA 1BFJA 1UURA 4NWGA 5EHPA 4JEGA 1A07A 2K7AB 4JE4A 2EO3A 1FU6A 1O4GA 2EU0A 4K45A 3VS1A 3S8NA 2EOBA 4OHDA 1KC2A 3EAZA 3VRRA 3IMJA 1D4TA 3K2MA 1OO4A 5HKZA 3EACA 2OZOA 5I6VA 2CRHA 3S8LA 3BKBA 1O43A 1AYDA 1CJ1A 2IUIA 4WWQA 4LUDA 3PFVA 4L1BB 2ABLA 2B3OA 4OHIA 1BKMA 3VS4A 5IBMA 1F1WA 3PLFB 4D8KA 2H5KA 1TZEE 2EO6A 3MXYA 1O47A 2PTKA 1AYAA 1RQQC 1O4FA 1TCEA 4FL2A
chains in the Genus database with same CATH superfamily
2VIFA 2LNWA 3M7FA 1KSWA 1O4EA 4QSYA 1JYRA 1ZFPE 2RMXA 2SHPA 3MXCA 3WA4A 5HKYA 2CS0A 2PLDA 3CD3A 3OP0A 4GWFA 1AB2A 3HIZB 1A09A 4K44A 5DF6A 2PLEA 1LCKA 1LCJA 3VS7A 1IJRA 1JYQA 1NZLA 1BF5A 3PJPA 2JYQA 3KFJA 1AYBA 1O45A 3CWGA 4P9VA 1BLKA 2BBUA 1FBZA 1FBVA 5IBSA 1M61A 3VRQA 4K2RA 4NWFA 1O4JA 2LQNA 1NRVA 4E93A 2AUGA 1O4CA 1OPLA 1IS0A 2GSBA 1SHDA 1AOTF 1O4OA 4OHLA 4F5BA 4EIHA 4ROJA 1O46A 1YVHA 1O49A 2IUHA 1WQUA 3VRNA 1X6CA 3T04A 3CXLA 3VS5A 2XP1A 1PICA 2EYVA 2GE9A 2IUGA 1R1PA 1JU5A 2IZVA 2DVJA 1O4AA 5D0JA 1SHAA 2CR4A 1GHUA 3N8MA 4U1PA 3VS3A 1LKLA 1RJAA 3MAZA 1MILA 5GJHA 1BHHB 2HDVA 1D4WA 3OB1B 3OVEA 2Y3AB 2DCRA 2DLYA 1SHBA 1O4HA 2DM0A 2ETZA 2MK2A 1MW4A 1LUMA 2RSYA 1AD5A 1O44A 2C9WA 2H46E 4DGPA 4K11A 1Y1UA 4E68A 4FL3A 3BUXB 2HMHA 2MRJA 4DGXA 2RVFA 3PSKA 5EG3B 1B47A 1A1AA 1O4MA 4TZIA 3OB2B 4H34A 2CBLA 1K9AA 1BLJA 3VS6A 1O4BA 5EHRA 3IN7A 1O4DA 1H9OA 3QWXX 2QMSA 2L6KA 2MC1A 2MRKA 2CI8A 3PQZA 1QCFA 3IN8A 1CSYA 3GXXA 1HCSB 1CWEA 3US4A 5KAZA 2KGYA 4GL9E 1JWOA 3N84A 5DC0B 1R1QA 4XZ1A 1O4KA 1HCTB 4JGHA 4FBNA 3UF4A 1CSZA 3GXWA 3BUNB 1A08A 2KNOA 1KA7A 4EY0A 4M4ZA 1GRIA 2CI9A 4LUEA 1BHHA 2CIAA 1LUKA 5EELA 3VROA 3S8OA 2EKXA 4A4BA 5DC4A 2L4KA 5J3XA 2EYZA 4U17A 2AOBA 3VRYA 2OQ1A 2LCTA 2SRCA 1RPYA 2KK6A 1F2FA 2FO0A 1QADA 3VS0A 4OHEA 1LKKA 3N7YA 1KA6A 2PNBA 1SPRA 2LQWA 1X0NA 2HCKA 3VGOA 1FMKA 1O41A 3QWYA 2C0TA 3K2TA 2L3TA 4A4CA 1O4LA 1OO3A 5HKWA 3VS2A 3NHNA 1G83A 2Y1NA 3BUMB 3TL0A 3C7IA 1UUSA 1BMBA 4F5AA 1BFIA 3BUOB 5EEQA 1SPSA 3VRPA 3VRZA 1A1EA 4GPLB 1AOUF 1O4IA 2RORA 1AYCA 1XA6A 2PNAA 3PSJA 3UYOA 1OPKA 1FYRA 1R1SA 3TKZA 4OHHA 2FCIA 1A1BA 1QG1E 1O42A 5DC9A 3LYVA 1JYUA 2HDXA 2Y1MA 1LUNA 3PS5A 3OV1A 3GQIB 5BO4A 2H8HA 1FU5A 1BM2A 1O48A 1X27A 2EL8A 3CBLA 1Z3KA 1BKLA 4F59A 2HUWA 1M27A 2EYYA 4XZ0A 5CDWA 2LNXA 1I3ZA 1O4NA 2YSXA 2DLZA 1P13A 1O4PA 4P9ZA 5AXIA 2K79B 1CWDL 2DX0A 5AULA 2C0IA 1A1CA 1YVLA 1SKJA 4H1OA 1BG1A 3S9KA 2AOAA 1Y57A 1O4RA 1NZVA 3BUWB 2YU7A 1A81A 2ECDA 3HHMB 3IMDA 1BHFA 1FHSA 1O4QA 5GJIA 1D1ZA 2MQIA 2C0OA 4X6SA 3ZNIA 1LUIA 3HCKA 1BFJA 1UURA 4NWGA 5EHPA 4JEGA 1A07A 2K7AB 4JE4A 2EO3A 1FU6A 1O4GA 2EU0A 4K45A 3VS1A 3S8NA 2EOBA 4OHDA 1KC2A 3EAZA 3VRRA 3IMJA 2LRAA 1D4TA 3K2MA 1OO4A 5HKZA 3EACA 2OZOA 5I6VA 2CRHA 3S8LA 3BKBA 1O43A 1AYDA 1CJ1A 2IUIA 4WWQA 4LUDA 3PFVA 4L1BB 2ABLA 2B3OA 4OHIA 1BKMA 3VS4A 5IBMA 1F1WA 3PLFB 4D8KA 2H5KA 1TZEE 2EO6A 3MXYA 1O47A 2PTKA 1AYAA 1RQQC 1O4FA 1TCEA 4FL2A
chains in the Genus database with same CATH topology
2VIFA 2LNWA 3M7FA 1KSWA 1O4EA 4QSYA 1JYRA 1ZFPE 2RMXA 2SHPA 3MXCA 3WA4A 5HKYA 2CS0A 2PLDA 3CD3A 3OP0A 4GWFA 1AB2A 3HIZB 1A09A 4K44A 5DF6A 2PLEA 1LCKA 1LCJA 3VS7A 1IJRA 1JYQA 1NZLA 1BF5A 3PJPA 2JYQA 3KFJA 1AYBA 1O45A 3CWGA 4P9VA 1BLKA 2BBUA 1FBZA 1FBVA 5IBSA 1M61A 3VRQA 4K2RA 4NWFA 1O4JA 2LQNA 1NRVA 4E93A 2AUGA 1O4CA 1OPLA 1IS0A 2GSBA 1SHDA 1AOTF 1O4OA 4OHLA 4F5BA 4EIHA 4ROJA 1O46A 1YVHA 1O49A 2IUHA 1WQUA 3VRNA 1X6CA 3T04A 3CXLA 3VS5A 2XP1A 1PICA 2EYVA 2GE9A 2IUGA 1R1PA 1JU5A 2IZVA 2DVJA 1O4AA 5D0JA 1SHAA 2CR4A 1GHUA 3N8MA 4U1PA 3VS3A 1LKLA 1RJAA 3MAZA 1MILA 5GJHA 1BHHB 2HDVA 1D4WA 3OB1B 3OVEA 2Y3AB 2DCRA 2DLYA 1SHBA 1O4HA 2DM0A 2ETZA 2MK2A 1MW4A 1LUMA 2RSYA 1AD5A 1O44A 2C9WA 2H46E 4DGPA 4K11A 1Y1UA 4E68A 4FL3A 3BUXB 2HMHA 2MRJA 4DGXA 2RVFA 3PSKA 5EG3B 1B47A 1A1AA 1O4MA 4TZIA 3OB2B 4H34A 2CBLA 1K9AA 1BLJA 3VS6A 1O4BA 5EHRA 3IN7A 1O4DA 1H9OA 3QWXX 2QMSA 2L6KA 2MC1A 2MRKA 2CI8A 3PQZA 1QCFA 3IN8A 1CSYA 3GXXA 1HCSB 1CWEA 3US4A 5KAZA 4GL9E 1JWOA 3N84A 5DC0B 1R1QA 4XZ1A 1O4KA 1HCTB 4JGHA 4FBNA 3UF4A 1CSZA 3GXWA 3BUNB 1A08A 2KNOA 1KA7A 4EY0A 4M4ZA 1GRIA 2CI9A 4LUEA 1BHHA 2CIAA 1LUKA 5EELA 3VROA 3S8OA 2EKXA 4A4BA 5DC4A 2L4KA 5J3XA 2EYZA 4U17A 2AOBA 3VRYA 2OQ1A 2LCTA 2SRCA 1RPYA 2KK6A 1F2FA 2FO0A 1QADA 3VS0A 4OHEA 1LKKA 3N7YA 1KA6A 2PNBA 1SPRA 2LQWA 1X0NA 2HCKA 3VGOA 1FMKA 1O41A 3QWYA 2C0TA 2L3TA 4A4CA 1O4LA 1OO3A 5HKWA 3VS2A 3NHNA 1G83A 2Y1NA 3BUMB 3TL0A 3C7IA 1UUSA 1BMBA 4F5AA 1BFIA 3BUOB 5EEQA 1SPSA 3VRPA 3VRZA 1A1EA 4GPLB 1AOUF 1O4IA 2RORA 1AYCA 1XA6A 2PNAA 3PSJA 3UYOA 1OPKA 1FYRA 1R1SA 3TKZA 4OHHA 2FCIA 1A1BA 1QG1E 1O42A 5DC9A 1JYUA 2HDXA 2Y1MA 1LUNA 3PS5A 3OV1A 3GQIB 5BO4A 2H8HA 1FU5A 1BM2A 1O48A 1X27A 2EL8A 3CBLA 1Z3KA 1BKLA 4F59A 2HUWA 1M27A 2EYYA 4XZ0A 5CDWA 2LNXA 1I3ZA 1O4NA 2YSXA 2DLZA 1P13A 1O4PA 4P9ZA 5AXIA 2K79B 1CWDL 2DX0A 5AULA 2C0IA 1A1CA 1YVLA 1SKJA 4H1OA 1BG1A 3S9KA 2AOAA 1Y57A 1O4RA 1NZVA 3BUWB 2YU7A 1A81A 2ECDA 3HHMB 3IMDA 1BHFA 1FHSA 1O4QA 5GJIA 1D1ZA 2MQIA 2C0OA 4X6SA 3ZNIA 1LUIA 3HCKA 1BFJA 1UURA 4NWGA 5EHPA 4JEGA 1A07A 2K7AB 4JE4A 2EO3A 1FU6A 1O4GA 2EU0A 4K45A 3VS1A 3S8NA 2EOBA 4OHDA 1KC2A 3EAZA 3VRRA 3IMJA 1D4TA 3K2MA 1OO4A 5HKZA 3EACA 2OZOA 5I6VA 2CRHA 3S8LA 3BKBA 1O43A 1AYDA 1CJ1A 2IUIA 4WWQA 4LUDA 3PFVA 4L1BB 2ABLA 2B3OA 4OHIA 1BKMA 3VS4A 5IBMA 1F1WA 3PLFB 4D8KA 2H5KA 1TZEE 2EO6A 3MXYA 1O47A 2PTKA 1AYAA 1RQQC 1O4FA 1TCEA 4FL2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VIF A;  2LNW A;  3M7F A;  1KSW A;  1O4E A;  4QSY A;  1JYR A;  1ZFP E;  2RMX A;  2SHP A;  3MXC A;  3WA4 A;  5HKY A;  2CS0 A;  2PLD A;  3CD3 A;  3OP0 A;  4GWF A;  1AB2 A;  3HIZ B;  1A09 A;  4K44 A;  5DF6 A;  2PLE A;  1LCK A;  1LCJ A;  3VS7 A;  1IJR A;  1JYQ A;  1NZL A;  1BF5 A;  3PJP A;  2JYQ A;  3KFJ A;  1AYB A;  1O45 A;  3CWG A;  4P9V A;  1BLK A;  2BBU A;  1FBZ A;  1FBV A;  5IBS A;  1M61 A;  3VRQ A;  4K2R A;  4NWF A;  1O4J A;  2LQN A;  1NRV A;  4E93 A;  2AUG A;  1O4C A;  1OPL A;  1IS0 A;  2GSB A;  1SHD A;  1AOT F;  1O4O A;  4OHL A;  4F5B A;  4EIH A;  4ROJ A;  1O46 A;  1YVH A;  1O49 A;  2IUH A;  1WQU A;  3VRN A;  1X6C A;  3T04 A;  3CXL A;  3VS5 A;  2XP1 A;  1PIC A;  2EYV A;  2GE9 A;  2IUG A;  1R1P A;  1JU5 A;  2IZV A;  2DVJ A;  1O4A A;  5D0J A;  1SHA A;  2CR4 A;  1GHU A;  3N8M A;  4U1P A;  3VS3 A;  1LKL A;  1RJA A;  3MAZ A;  1MIL A;  5GJH A;  1BHH B;  2HDV A;  1D4W A;  3OB1 B;  3OVE A;  2Y3A B;  2DCR A;  2DLY A;  1SHB A;  1O4H A;  2DM0 A;  2ETZ A;  2MK2 A;  1MW4 A;  1LUM A;  2RSY A;  1AD5 A;  1O44 A;  2C9W A;  2H46 E;  4DGP A;  4K11 A;  1Y1U A;  4E68 A;  4FL3 A;  3BUX B;  2HMH A;  2MRJ A;  4DGX A;  2RVF A;  3PSK A;  5EG3 B;  1B47 A;  1A1A A;  1O4M A;  4TZI A;  3OB2 B;  4H34 A;  2CBL A;  1K9A A;  1BLJ A;  3VS6 A;  1O4B A;  5EHR A;  3IN7 A;  1O4D A;  1H9O A;  3QWX X;  2QMS A;  2L6K A;  2MC1 A;  2MRK A;  2CI8 A;  3PQZ A;  1QCF A;  3IN8 A;  1CSY A;  3GXX A;  1HCS B;  1CWE A;  3US4 A;  5KAZ A;  4GL9 E;  1JWO A;  3N84 A;  5DC0 B;  1R1Q A;  4XZ1 A;  1O4K A;  1HCT B;  4JGH A;  4FBN A;  3UF4 A;  1CSZ A;  3GXW A;  3BUN B;  1A08 A;  2KNO A;  1KA7 A;  4EY0 A;  4M4Z A;  1GRI A;  2CI9 A;  4LUE A;  1BHH A;  2CIA A;  1LUK A;  5EEL A;  3VRO A;  3S8O A;  2EKX A;  4A4B A;  5DC4 A;  2L4K A;  5J3X A;  2EYZ A;  4U17 A;  2AOB A;  3VRY A;  2OQ1 A;  2LCT A;  2SRC A;  1RPY A;  2KK6 A;  1F2F A;  2FO0 A;  1QAD A;  3VS0 A;  4OHE A;  1LKK A;  3N7Y A;  1KA6 A;  2PNB A;  1SPR A;  2LQW A;  1X0N A;  2HCK A;  3VGO A;  1FMK A;  1O41 A;  3QWY A;  2C0T A;  2L3T A;  4A4C A;  1O4L A;  1OO3 A;  5HKW A;  3VS2 A;  3NHN A;  1G83 A;  2Y1N A;  3BUM B;  3TL0 A;  3C7I A;  1UUS A;  1BMB A;  4F5A A;  1BFI A;  3BUO B;  5EEQ A;  1SPS A;  3VRP A;  3VRZ A;  1A1E A;  4GPL B;  1AOU F;  1O4I A;  2ROR A;  1AYC A;  1XA6 A;  2PNA A;  3PSJ A;  3UYO A;  1OPK A;  1FYR A;  1R1S A;  3TKZ A;  4OHH A;  2FCI A;  1A1B A;  1QG1 E;  1O42 A;  5DC9 A;  1JYU A;  2HDX A;  2Y1M A;  1LUN A;  3PS5 A;  3OV1 A;  3GQI B;  5BO4 A;  2H8H A;  1FU5 A;  1BM2 A;  1O48 A;  1X27 A;  2EL8 A;  3CBL A;  1Z3K A;  1BKL A;  4F59 A;  2HUW A;  1M27 A;  2EYY A;  4XZ0 A;  5CDW A;  2LNX A;  1I3Z A;  1O4N A;  2YSX A;  2DLZ A;  1P13 A;  1O4P A;  4P9Z A;  5AXI A;  2K79 B;  1CWD L;  2DX0 A;  5AUL A;  2C0I A;  1A1C A;  1YVL A;  1SKJ A;  4H1O A;  1BG1 A;  3S9K A;  2AOA A;  1Y57 A;  1O4R A;  1NZV A;  3BUW B;  2YU7 A;  1A81 A;  2ECD A;  3HHM B;  3IMD A;  1BHF A;  1FHS A;  1O4Q A;  5GJI A;  1D1Z A;  2MQI A;  2C0O A;  4X6S A;  3ZNI A;  1LUI A;  3HCK A;  1BFJ A;  1UUR A;  4NWG A;  5EHP A;  4JEG A;  1A07 A;  2K7A B;  4JE4 A;  2EO3 A;  1FU6 A;  1O4G A;  2EU0 A;  4K45 A;  3VS1 A;  3S8N A;  2EOB A;  4OHD A;  1KC2 A;  3EAZ A;  3VRR A;  3IMJ A;  1D4T A;  3K2M A;  1OO4 A;  5HKZ A;  3EAC A;  2OZO A;  5I6V A;  2CRH A;  3S8L A;  3BKB A;  1O43 A;  1AYD A;  1CJ1 A;  2IUI A;  4WWQ A;  4LUD A;  3PFV A;  4L1B B;  2ABL A;  2B3O A;  4OHI A;  1BKM A;  3VS4 A;  5IBM A;  1F1W A;  3PLF B;  4D8K A;  2H5K A;  1TZE E;  2EO6 A;  3MXY A;  1O47 A;  2PTK A;  1AYA A;  1RQQ C;  1O4F A;  1TCE A;  4FL2 A; 
#chains in the Genus database with same CATH topology
 2VIF A;  2LNW A;  3M7F A;  1KSW A;  1O4E A;  4QSY A;  1JYR A;  1ZFP E;  2RMX A;  2SHP A;  3MXC A;  3WA4 A;  5HKY A;  2CS0 A;  2PLD A;  3CD3 A;  3OP0 A;  4GWF A;  1AB2 A;  3HIZ B;  1A09 A;  4K44 A;  5DF6 A;  2PLE A;  1LCK A;  1LCJ A;  3VS7 A;  1IJR A;  1JYQ A;  1NZL A;  1BF5 A;  3PJP A;  2JYQ A;  3KFJ A;  1AYB A;  1O45 A;  3CWG A;  4P9V A;  1BLK A;  2BBU A;  1FBZ A;  1FBV A;  5IBS A;  1M61 A;  3VRQ A;  4K2R A;  4NWF A;  1O4J A;  2LQN A;  1NRV A;  4E93 A;  2AUG A;  1O4C A;  1OPL A;  1IS0 A;  2GSB A;  1SHD A;  1AOT F;  1O4O A;  4OHL A;  4F5B A;  4EIH A;  4ROJ A;  1O46 A;  1YVH A;  1O49 A;  2IUH A;  1WQU A;  3VRN A;  1X6C A;  3T04 A;  3CXL A;  3VS5 A;  2XP1 A;  1PIC A;  2EYV A;  2GE9 A;  2IUG A;  1R1P A;  1JU5 A;  2IZV A;  2DVJ A;  1O4A A;  5D0J A;  1SHA A;  2CR4 A;  1GHU A;  3N8M A;  4U1P A;  3VS3 A;  1LKL A;  1RJA A;  3MAZ A;  1MIL A;  5GJH A;  1BHH B;  2HDV A;  1D4W A;  3OB1 B;  3OVE A;  2Y3A B;  2DCR A;  2DLY A;  1SHB A;  1O4H A;  2DM0 A;  2ETZ A;  2MK2 A;  1MW4 A;  1LUM A;  2RSY A;  1AD5 A;  1O44 A;  2C9W A;  2H46 E;  4DGP A;  4K11 A;  1Y1U A;  4E68 A;  4FL3 A;  3BUX B;  2HMH A;  2MRJ A;  4DGX A;  2RVF A;  3PSK A;  5EG3 B;  1B47 A;  1A1A A;  1O4M A;  4TZI A;  3OB2 B;  4H34 A;  2CBL A;  1K9A A;  1BLJ A;  3VS6 A;  1O4B A;  5EHR A;  3IN7 A;  1O4D A;  1H9O A;  3QWX X;  2QMS A;  2L6K A;  2MC1 A;  2MRK A;  2CI8 A;  3PQZ A;  1QCF A;  3IN8 A;  1CSY A;  3GXX A;  1HCS B;  1CWE A;  3US4 A;  5KAZ A;  2KGY A;  4GL9 E;  1JWO A;  3N84 A;  5DC0 B;  1R1Q A;  4XZ1 A;  1O4K A;  1HCT B;  4JGH A;  4FBN A;  3UF4 A;  1CSZ A;  3GXW A;  3BUN B;  1A08 A;  2KNO A;  1KA7 A;  4EY0 A;  4M4Z A;  1GRI A;  2CI9 A;  4LUE A;  1BHH A;  2CIA A;  1LUK A;  5EEL A;  3VRO A;  3S8O A;  2EKX A;  4A4B A;  5DC4 A;  2L4K A;  5J3X A;  2EYZ A;  4U17 A;  2AOB A;  3VRY A;  2OQ1 A;  2LCT A;  2SRC A;  1RPY A;  2KK6 A;  1F2F A;  2FO0 A;  1QAD A;  3VS0 A;  4OHE A;  1LKK A;  3N7Y A;  1KA6 A;  2PNB A;  1SPR A;  2LQW A;  1X0N A;  2HCK A;  3VGO A;  1FMK A;  1O41 A;  3QWY A;  2C0T A;  3K2T A;  2L3T A;  4A4C A;  1O4L A;  1OO3 A;  5HKW A;  3VS2 A;  3NHN A;  1G83 A;  2Y1N A;  3BUM B;  3TL0 A;  3C7I A;  1UUS A;  1BMB A;  4F5A A;  1BFI A;  3BUO B;  5EEQ A;  1SPS A;  3VRP A;  3VRZ A;  1A1E A;  4GPL B;  1AOU F;  1O4I A;  2ROR A;  1AYC A;  1XA6 A;  2PNA A;  3PSJ A;  3UYO A;  1OPK A;  1FYR A;  1R1S A;  3TKZ A;  4OHH A;  2FCI A;  1A1B A;  1QG1 E;  1O42 A;  5DC9 A;  3LYV A;  1JYU A;  2HDX A;  2Y1M A;  1LUN A;  3PS5 A;  3OV1 A;  3GQI B;  5BO4 A;  2H8H A;  1FU5 A;  1BM2 A;  1O48 A;  1X27 A;  2EL8 A;  3CBL A;  1Z3K A;  1BKL A;  4F59 A;  2HUW A;  1M27 A;  2EYY A;  4XZ0 A;  5CDW A;  2LNX A;  1I3Z A;  1O4N A;  2YSX A;  2DLZ A;  1P13 A;  1O4P A;  4P9Z A;  5AXI A;  2K79 B;  1CWD L;  2DX0 A;  5AUL A;  2C0I A;  1A1C A;  1YVL A;  1SKJ A;  4H1O A;  1BG1 A;  3S9K A;  2AOA A;  1Y57 A;  1O4R A;  1NZV A;  3BUW B;  2YU7 A;  1A81 A;  2ECD A;  3HHM B;  3IMD A;  1BHF A;  1FHS A;  1O4Q A;  5GJI A;  1D1Z A;  2MQI A;  2C0O A;  4X6S A;  3ZNI A;  1LUI A;  3HCK A;  1BFJ A;  1UUR A;  4NWG A;  5EHP A;  4JEG A;  1A07 A;  2K7A B;  4JE4 A;  2EO3 A;  1FU6 A;  1O4G A;  2EU0 A;  4K45 A;  3VS1 A;  3S8N A;  2EOB A;  4OHD A;  1KC2 A;  3EAZ A;  3VRR A;  3IMJ A;  2LRA A;  1D4T A;  3K2M A;  1OO4 A;  5HKZ A;  3EAC A;  2OZO A;  5I6V A;  2CRH A;  3S8L A;  3BKB A;  1O43 A;  1AYD A;  1CJ1 A;  2IUI A;  4WWQ A;  4LUD A;  3PFV A;  4L1B B;  2ABL A;  2B3O A;  4OHI A;  1BKM A;  3VS4 A;  5IBM A;  1F1W A;  3PLF B;  4D8K A;  2H5K A;  1TZE E;  2EO6 A;  3MXY A;  1O47 A;  2PTK A;  1AYA A;  1RQQ C;  1O4F A;  1TCE A;  4FL2 A; 
#chains in the Genus database with same CATH homology
 2VIF A;  2LNW A;  3M7F A;  1KSW A;  1O4E A;  4QSY A;  1JYR A;  1ZFP E;  2RMX A;  2SHP A;  3MXC A;  3WA4 A;  5HKY A;  2CS0 A;  2PLD A;  3CD3 A;  3OP0 A;  4GWF A;  1AB2 A;  3HIZ B;  1A09 A;  4K44 A;  5DF6 A;  2PLE A;  1LCK A;  1LCJ A;  3VS7 A;  1IJR A;  1JYQ A;  1NZL A;  1BF5 A;  3PJP A;  2JYQ A;  3KFJ A;  1AYB A;  1O45 A;  3CWG A;  4P9V A;  1BLK A;  2BBU A;  1FBZ A;  1FBV A;  5IBS A;  1M61 A;  3VRQ A;  4K2R A;  4NWF A;  1O4J A;  2LQN A;  1NRV A;  4E93 A;  2AUG A;  1O4C A;  1OPL A;  1IS0 A;  2GSB A;  1SHD A;  1AOT F;  1O4O A;  4OHL A;  4F5B A;  4EIH A;  4ROJ A;  1O46 A;  1YVH A;  1O49 A;  2IUH A;  1WQU A;  3VRN A;  1X6C A;  3T04 A;  3CXL A;  3VS5 A;  2XP1 A;  1PIC A;  2EYV A;  2GE9 A;  2IUG A;  1R1P A;  1JU5 A;  2IZV A;  2DVJ A;  1O4A A;  5D0J A;  1SHA A;  2CR4 A;  1GHU A;  3N8M A;  4U1P A;  3VS3 A;  1LKL A;  1RJA A;  3MAZ A;  1MIL A;  5GJH A;  1BHH B;  2HDV A;  1D4W A;  3OB1 B;  3OVE A;  2Y3A B;  2DCR A;  2DLY A;  1SHB A;  1O4H A;  2DM0 A;  2ETZ A;  2MK2 A;  1MW4 A;  1LUM A;  2RSY A;  1AD5 A;  1O44 A;  2C9W A;  2H46 E;  4DGP A;  4K11 A;  1Y1U A;  4E68 A;  4FL3 A;  3BUX B;  2HMH A;  2MRJ A;  4DGX A;  2RVF A;  3PSK A;  5EG3 B;  1B47 A;  1A1A A;  1O4M A;  4TZI A;  3OB2 B;  4H34 A;  2CBL A;  1K9A A;  1BLJ A;  3VS6 A;  1O4B A;  5EHR A;  3IN7 A;  1O4D A;  1H9O A;  3QWX X;  2QMS A;  2L6K A;  2MC1 A;  2MRK A;  2CI8 A;  3PQZ A;  1QCF A;  3IN8 A;  1CSY A;  3GXX A;  1HCS B;  1CWE A;  3US4 A;  5KAZ A;  4GL9 E;  1JWO A;  3N84 A;  5DC0 B;  1R1Q A;  4XZ1 A;  1O4K A;  1HCT B;  4JGH A;  4FBN A;  3UF4 A;  1CSZ A;  3GXW A;  3BUN B;  1A08 A;  2KNO A;  1KA7 A;  4EY0 A;  4M4Z A;  1GRI A;  2CI9 A;  4LUE A;  1BHH A;  2CIA A;  1LUK A;  5EEL A;  3VRO A;  3S8O A;  2EKX A;  4A4B A;  5DC4 A;  2L4K A;  5J3X A;  2EYZ A;  4U17 A;  2AOB A;  3VRY A;  2OQ1 A;  2LCT A;  2SRC A;  1RPY A;  2KK6 A;  1F2F A;  2FO0 A;  1QAD A;  3VS0 A;  4OHE A;  1LKK A;  3N7Y A;  1KA6 A;  2PNB A;  1SPR A;  2LQW A;  1X0N A;  2HCK A;  3VGO A;  1FMK A;  1O41 A;  3QWY A;  2C0T A;  2L3T A;  4A4C A;  1O4L A;  1OO3 A;  5HKW A;  3VS2 A;  3NHN A;  1G83 A;  2Y1N A;  3BUM B;  3TL0 A;  3C7I A;  1UUS A;  1BMB A;  4F5A A;  1BFI A;  3BUO B;  5EEQ A;  1SPS A;  3VRP A;  3VRZ A;  1A1E A;  4GPL B;  1AOU F;  1O4I A;  2ROR A;  1AYC A;  1XA6 A;  2PNA A;  3PSJ A;  3UYO A;  1OPK A;  1FYR A;  1R1S A;  3TKZ A;  4OHH A;  2FCI A;  1A1B A;  1QG1 E;  1O42 A;  5DC9 A;  1JYU A;  2HDX A;  2Y1M A;  1LUN A;  3PS5 A;  3OV1 A;  3GQI B;  5BO4 A;  2H8H A;  1FU5 A;  1BM2 A;  1O48 A;  1X27 A;  2EL8 A;  3CBL A;  1Z3K A;  1BKL A;  4F59 A;  2HUW A;  1M27 A;  2EYY A;  4XZ0 A;  5CDW A;  2LNX A;  1I3Z A;  1O4N A;  2YSX A;  2DLZ A;  1P13 A;  1O4P A;  4P9Z A;  5AXI A;  2K79 B;  1CWD L;  2DX0 A;  5AUL A;  2C0I A;  1A1C A;  1YVL A;  1SKJ A;  4H1O A;  1BG1 A;  3S9K A;  2AOA A;  1Y57 A;  1O4R A;  1NZV A;  3BUW B;  2YU7 A;  1A81 A;  2ECD A;  3HHM B;  3IMD A;  1BHF A;  1FHS A;  1O4Q A;  5GJI A;  1D1Z A;  2MQI A;  2C0O A;  4X6S A;  3ZNI A;  1LUI A;  3HCK A;  1BFJ A;  1UUR A;  4NWG A;  5EHP A;  4JEG A;  1A07 A;  2K7A B;  4JE4 A;  2EO3 A;  1FU6 A;  1O4G A;  2EU0 A;  4K45 A;  3VS1 A;  3S8N A;  2EOB A;  4OHD A;  1KC2 A;  3EAZ A;  3VRR A;  3IMJ A;  1D4T A;  3K2M A;  1OO4 A;  5HKZ A;  3EAC A;  2OZO A;  5I6V A;  2CRH A;  3S8L A;  3BKB A;  1O43 A;  1AYD A;  1CJ1 A;  2IUI A;  4WWQ A;  4LUD A;  3PFV A;  4L1B B;  2ABL A;  2B3O A;  4OHI A;  1BKM A;  3VS4 A;  5IBM A;  1F1W A;  3PLF B;  4D8K A;  2H5K A;  1TZE E;  2EO6 A;  3MXY A;  1O47 A;  2PTK A;  1AYA A;  1RQQ C;  1O4F A;  1TCE A;  4FL2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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