5DF6A

Crystal structure of ptpn11 tandem sh2 domains in complex with a txnip peptide
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
217
structure length
212
Chain Sequence
RRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTGDYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESKSKVTHVMIRCQKYDVGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 11
total genus 56
structure length 212
sequence length 217
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2015-08-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5df6A01
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5df6A02
1O4JA 4GPLB 5EHPA 2PTKA 4F59A 2GE9A 4U1PA 4A4BA 1JYUA 2YU7A 3WA4A 2FO0A 2MQIA 3VGOA 3EAZA 1BFJA 1OPKA 3NHNA 1LUNA 2DX0A 1P13A 2DM0A 2EYZA 2HDXA 3PJPA 5KAZA 3PFVA 1PICA 2FCIA 1CWDL 3VS1A 5D0JA 2LQNA 1Z3KA 1I3ZA 2OQ1A 4XZ0A 4GWFA 4WWQA 2MK2A 4OHLA 4OHIA 3VS2A 4H34A 1BHFA 1A1AA 3HCKA 2IUHA 1RPYA 5IBMA 1Y1UA 3VS3A 1O4DA 2CIAA 1NZLA 1O4HA 1GRIA 3CD3A 3MXYA 2JYQA 1AOUF 1X6CA 2Y3AB 1O4BA 2EL8A 5CDWA 3PS5A 1O4LA 4F5AA 2OZOA 1G83A 1Y57A 3C7IA 3BUOB 1KC2A 1UUSA 1JYQA 2Y1MA 4D8KA 2BBUA 1O4AA 4NWFA 5HKWA 3IN8A 1SPRA 3BKBA 2VIFA 3PSKA 5DC9A 4OHEA 3TL0A 3MAZA 1HCSB 1A09A 1O4CA 4FL2A 3CBLA 4EY0A 2DVJA 2CRHA 2PLDA 1KSWA 1UURA 4M4ZA 2EU0A 2EYYA 2CBLA 2CI9A 1LUKA 3BUWB 2K79B 2C9WA 5BO4A 2HDVA 5GJHA 1WQUA 2QMSA 4OHDA 3VRPA 1R1PA 2EO3A 2CS0A 3CXLA 3VRQA 5DF6A 2C0TA 1D1ZA 1R1SA 2H46E 4FL3A 1MILA 1JWOA 4A4CA 1LKKA 1M27A 1A1EA 1D4TA 2EO6A 4DGXA 3BUNB 1KA6A 1YVHA 1B47A 2Y1NA 1D4WA 1FU5A 1O45A 3OV1A 5DC4A 3S8OA 1BHHB 2XP1A 4NWGA 1BKMA 1LUIA 3S8NA 1A1BA 3IMDA 4K11A 2RMXA 1KA7A 1O4EA 2MC1A 3GXXA 2B3OA 2SRCA 2YSXA 3HIZB 2RVFA 2AOAA 4K44A 3OP0A 1AD5A 5EG3B 1M61A 1FHSA 1OO4A 1IS0A 1BMBA 2LCTA 1QCFA 2PNAA 3IN7A 4LUEA 5GJIA 1O4GA 3ZNIA 3VRZA 2ETZA 1BHHA 1O4FA 3OB2B 1QADA 1NZVA 1CWEA 5I6VA 1O48A 1F2FA 1SPSA 1TCEA 2AOBA 2IZVA 1ZFPE 4K2RA 4H1OA 1YVLA 3S9KA 1R1QA 1GHUA 1TZEE 3VRRA 5J3XA 3VRYA 1O4KA 2LQWA 1LCJA 3QWYA 4FBNA 4OHHA 1O47A 2HUWA 1O4PA 1FBZA 2EKXA 3BUXB 1O4IA 3PQZA 1CSZA 3M7FA 3T04A 1NRVA 3VS6A 4L1BB 3UF4A 1H9OA 1RQQC 3US4A 2KK6A 4F5BA 2PNBA 3VS0A 2EYVA 2LNXA 3IMJA 1FMKA 2L4KA 2C0IA 2HCKA 3N7YA 2DCRA 1AB2A 3KFJA 2H8HA 1AOTF 1CJ1A 1X0NA 1A07A 2IUGA 5HKYA 1IJRA 3GXWA 1AYDA 2EOBA 4JGHA 1O4RA 1FBVA 3PLFB 1JYRA 2L3TA 4JE4A 4K45A 5EHRA 3MXCA 1RJAA 5AULA 2CI8A 4X6SA 3N84A 5HKZA 5IBSA 2CR4A 2ABLA 2KNOA 4U17A 3CWGA 1F1WA 3OVEA 3S8LA 2PLEA 4E68A 3N8MA 2IUIA 4ROJA 1QG1E 1AYCA 3VRNA 2RORA 3VS4A 1BFIA 1O42A 2L6KA 1LKLA 2ECDA 3OB1B 4JEGA 2MRKA 3QWXX 4XZ1A 1O4MA 2RSYA 2C0OA 2GSBA 1LCKA 1FYRA 2MRJA 1BF5A 1SKJA 1A1CA 3UYOA 1MW4A 1O44A 1CSYA 1A81A 1BM2A 1O43A 1LUMA 2HMHA 1BLKA 1OPLA 2DLYA 4EIHA 2LNWA 5AXIA 1BKLA 5DC0B 4DGPA 2K7AB 1O46A 1BG1A 4TZIA 1A08A 2DLZA 2H5KA 1FU6A 1XA6A 3VROA 3TKZA 1BLJA 4LUDA 1K9AA 1SHDA 4P9ZA 4P9VA 4QSYA 3GQIB 3EACA 4E93A 3VS5A 1O4OA 2SHPA 1O41A 5EELA 2AUGA 1O4NA 3BUMB 1JU5A 1SHAA 3K2MA 1O4QA 1AYBA 3HHMB 4GL9E 5EEQA 1X27A 1AYAA 1HCTB 3VS7A 1SHBA 1OO3A 1O49A 3PSJA
chains in the Genus database with same CATH superfamily
1O4JA 4GPLB 5EHPA 2PTKA 4F59A 2GE9A 4U1PA 4A4BA 1JYUA 2YU7A 3WA4A 2FO0A 2MQIA 3VGOA 3EAZA 1BFJA 1OPKA 3NHNA 1LUNA 2DX0A 1P13A 2DM0A 2EYZA 2HDXA 3PJPA 5KAZA 3PFVA 1PICA 2FCIA 1CWDL 3VS1A 5D0JA 2LQNA 1Z3KA 1I3ZA 2OQ1A 4XZ0A 4GWFA 4WWQA 2MK2A 4OHLA 4OHIA 3VS2A 4H34A 1BHFA 1A1AA 3HCKA 2IUHA 1RPYA 5IBMA 1Y1UA 3VS3A 1O4DA 2CIAA 1NZLA 1O4HA 1GRIA 3CD3A 3MXYA 2JYQA 1AOUF 1X6CA 2Y3AB 1O4BA 2EL8A 5CDWA 3PS5A 1O4LA 4F5AA 2OZOA 1G83A 1Y57A 3C7IA 3BUOB 1KC2A 1UUSA 1JYQA 2Y1MA 4D8KA 2BBUA 1O4AA 4NWFA 5HKWA 3IN8A 1SPRA 3BKBA 2VIFA 3PSKA 5DC9A 4OHEA 3TL0A 3MAZA 1HCSB 1A09A 1O4CA 4FL2A 3CBLA 4EY0A 2DVJA 2CRHA 2PLDA 1KSWA 1UURA 4M4ZA 2EU0A 2EYYA 2CBLA 2CI9A 1LUKA 3BUWB 2K79B 2C9WA 5BO4A 2HDVA 5GJHA 1WQUA 2QMSA 4OHDA 3VRPA 1R1PA 2EO3A 2CS0A 3CXLA 3VRQA 5DF6A 2C0TA 1D1ZA 1R1SA 2H46E 4FL3A 1MILA 2KGYA 1JWOA 4A4CA 1LKKA 1M27A 1A1EA 1D4TA 2EO6A 4DGXA 3BUNB 1KA6A 1YVHA 1B47A 2Y1NA 1D4WA 1FU5A 1O45A 3OV1A 5DC4A 3S8OA 1BHHB 2XP1A 4NWGA 1BKMA 1LUIA 3S8NA 1A1BA 3IMDA 4K11A 2RMXA 2LRAA 1KA7A 1O4EA 2MC1A 3GXXA 2B3OA 2SRCA 2YSXA 3HIZB 2RVFA 2AOAA 4K44A 3OP0A 1AD5A 5EG3B 1M61A 1FHSA 1OO4A 1IS0A 1BMBA 2LCTA 1QCFA 2PNAA 3IN7A 4LUEA 5GJIA 1O4GA 3ZNIA 3VRZA 2ETZA 1BHHA 1O4FA 3OB2B 1QADA 1NZVA 1CWEA 5I6VA 1O48A 1F2FA 1SPSA 1TCEA 2AOBA 2IZVA 1ZFPE 4K2RA 4H1OA 1YVLA 3S9KA 1R1QA 1GHUA 1TZEE 3VRRA 5J3XA 3VRYA 1O4KA 3K2TA 2LQWA 1LCJA 3QWYA 4FBNA 4OHHA 1O47A 2HUWA 1O4PA 1FBZA 2EKXA 3BUXB 1O4IA 3PQZA 1CSZA 3M7FA 3T04A 1NRVA 3VS6A 4L1BB 3UF4A 1H9OA 1RQQC 3US4A 2KK6A 4F5BA 2PNBA 3VS0A 2EYVA 2LNXA 3IMJA 1FMKA 2L4KA 2C0IA 2HCKA 3N7YA 2DCRA 1AB2A 3KFJA 2H8HA 1AOTF 1CJ1A 1X0NA 1A07A 2IUGA 5HKYA 1IJRA 3GXWA 1AYDA 2EOBA 4JGHA 1O4RA 1FBVA 3PLFB 1JYRA 2L3TA 4JE4A 4K45A 5EHRA 3MXCA 1RJAA 5AULA 2CI8A 4X6SA 3N84A 5HKZA 5IBSA 2CR4A 2ABLA 2KNOA 4U17A 3CWGA 1F1WA 3OVEA 3S8LA 2PLEA 4E68A 3N8MA 2IUIA 4ROJA 1QG1E 1AYCA 3VRNA 2RORA 3VS4A 1BFIA 1O42A 2L6KA 1LKLA 2ECDA 3OB1B 4JEGA 2MRKA 3QWXX 4XZ1A 1O4MA 2RSYA 2C0OA 2GSBA 1LCKA 1FYRA 2MRJA 1BF5A 1SKJA 1A1CA 3UYOA 1MW4A 1O44A 1CSYA 1A81A 1BM2A 1O43A 1LUMA 2HMHA 1BLKA 1OPLA 2DLYA 4EIHA 2LNWA 5AXIA 1BKLA 5DC0B 4DGPA 2K7AB 1O46A 1BG1A 4TZIA 1A08A 2DLZA 2H5KA 1FU6A 1XA6A 3VROA 3TKZA 1BLJA 4LUDA 1K9AA 1SHDA 4P9ZA 4P9VA 4QSYA 3GQIB 3EACA 4E93A 3VS5A 1O4OA 2SHPA 1O41A 5EELA 2AUGA 1O4NA 3BUMB 3LYVA 1JU5A 1SHAA 3K2MA 1O4QA 1AYBA 3HHMB 4GL9E 5EEQA 1X27A 1AYAA 1HCTB 3VS7A 1SHBA 1OO3A 1O49A 3PSJA
chains in the Genus database with same CATH topology
1O4JA 4GPLB 5EHPA 2PTKA 4F59A 2GE9A 4U1PA 4A4BA 1JYUA 2YU7A 3WA4A 2FO0A 2MQIA 3VGOA 3EAZA 1BFJA 1OPKA 3NHNA 1LUNA 2DX0A 1P13A 2DM0A 2EYZA 2HDXA 3PJPA 5KAZA 3PFVA 1PICA 2FCIA 1CWDL 3VS1A 5D0JA 2LQNA 1Z3KA 1I3ZA 2OQ1A 4XZ0A 4GWFA 4WWQA 2MK2A 4OHLA 4OHIA 3VS2A 4H34A 1BHFA 1A1AA 3HCKA 2IUHA 1RPYA 5IBMA 1Y1UA 3VS3A 1O4DA 2CIAA 1NZLA 1O4HA 1GRIA 3CD3A 3MXYA 2JYQA 1AOUF 1X6CA 2Y3AB 1O4BA 2EL8A 5CDWA 3PS5A 1O4LA 4F5AA 2OZOA 1G83A 1Y57A 3C7IA 3BUOB 1KC2A 1UUSA 1JYQA 2Y1MA 4D8KA 2BBUA 1O4AA 4NWFA 5HKWA 3IN8A 1SPRA 3BKBA 2VIFA 3PSKA 5DC9A 4OHEA 3TL0A 3MAZA 1HCSB 1A09A 1O4CA 4FL2A 3CBLA 4EY0A 2DVJA 2CRHA 2PLDA 1KSWA 1UURA 4M4ZA 2EU0A 2EYYA 2CBLA 2CI9A 1LUKA 3BUWB 2K79B 2C9WA 5BO4A 2HDVA 5GJHA 1WQUA 2QMSA 4OHDA 3VRPA 1R1PA 2EO3A 2CS0A 3CXLA 3VRQA 5DF6A 2C0TA 1D1ZA 1R1SA 2H46E 4FL3A 1MILA 1JWOA 4A4CA 1LKKA 1M27A 1A1EA 1D4TA 2EO6A 4DGXA 3BUNB 1KA6A 1YVHA 1B47A 2Y1NA 1D4WA 1FU5A 1O45A 3OV1A 5DC4A 3S8OA 1BHHB 2XP1A 4NWGA 1BKMA 1LUIA 3S8NA 1A1BA 3IMDA 4K11A 2RMXA 1KA7A 1O4EA 2MC1A 3GXXA 2B3OA 2SRCA 2YSXA 3HIZB 2RVFA 2AOAA 4K44A 3OP0A 1AD5A 5EG3B 1M61A 1FHSA 1OO4A 1IS0A 1BMBA 2LCTA 1QCFA 2PNAA 3IN7A 4LUEA 5GJIA 1O4GA 3ZNIA 3VRZA 2ETZA 1BHHA 1O4FA 3OB2B 1QADA 1NZVA 1CWEA 5I6VA 1O48A 1F2FA 1SPSA 1TCEA 2AOBA 2IZVA 1ZFPE 4K2RA 4H1OA 1YVLA 3S9KA 1R1QA 1GHUA 1TZEE 3VRRA 5J3XA 3VRYA 1O4KA 2LQWA 1LCJA 3QWYA 4FBNA 4OHHA 1O47A 2HUWA 1O4PA 1FBZA 2EKXA 3BUXB 1O4IA 3PQZA 1CSZA 3M7FA 3T04A 1NRVA 3VS6A 4L1BB 3UF4A 1H9OA 1RQQC 3US4A 2KK6A 4F5BA 2PNBA 3VS0A 2EYVA 2LNXA 3IMJA 1FMKA 2L4KA 2C0IA 2HCKA 3N7YA 2DCRA 1AB2A 3KFJA 2H8HA 1AOTF 1CJ1A 1X0NA 1A07A 2IUGA 5HKYA 1IJRA 3GXWA 1AYDA 2EOBA 4JGHA 1O4RA 1FBVA 3PLFB 1JYRA 2L3TA 4JE4A 4K45A 5EHRA 3MXCA 1RJAA 5AULA 2CI8A 4X6SA 3N84A 5HKZA 5IBSA 2CR4A 2ABLA 2KNOA 4U17A 3CWGA 1F1WA 3OVEA 3S8LA 2PLEA 4E68A 3N8MA 2IUIA 4ROJA 1QG1E 1AYCA 3VRNA 2RORA 3VS4A 1BFIA 1O42A 2L6KA 1LKLA 2ECDA 3OB1B 4JEGA 2MRKA 3QWXX 4XZ1A 1O4MA 2RSYA 2C0OA 2GSBA 1LCKA 1FYRA 2MRJA 1BF5A 1SKJA 1A1CA 3UYOA 1MW4A 1O44A 1CSYA 1A81A 1BM2A 1O43A 1LUMA 2HMHA 1BLKA 1OPLA 2DLYA 4EIHA 2LNWA 5AXIA 1BKLA 5DC0B 4DGPA 2K7AB 1O46A 1BG1A 4TZIA 1A08A 2DLZA 2H5KA 1FU6A 1XA6A 3VROA 3TKZA 1BLJA 4LUDA 1K9AA 1SHDA 4P9ZA 4P9VA 4QSYA 3GQIB 3EACA 4E93A 3VS5A 1O4OA 2SHPA 1O41A 5EELA 2AUGA 1O4NA 3BUMB 1JU5A 1SHAA 3K2MA 1O4QA 1AYBA 3HHMB 4GL9E 5EEQA 1X27A 1AYAA 1HCTB 3VS7A 1SHBA 1OO3A 1O49A 3PSJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O4J A;  4GPL B;  5EHP A;  2PTK A;  4F59 A;  2GE9 A;  4U1P A;  4A4B A;  1JYU A;  2YU7 A;  3WA4 A;  2FO0 A;  2MQI A;  3VGO A;  3EAZ A;  1BFJ A;  1OPK A;  3NHN A;  1LUN A;  2DX0 A;  1P13 A;  2DM0 A;  2EYZ A;  2HDX A;  3PJP A;  5KAZ A;  3PFV A;  1PIC A;  2FCI A;  1CWD L;  3VS1 A;  5D0J A;  2LQN A;  1Z3K A;  1I3Z A;  2OQ1 A;  4XZ0 A;  4GWF A;  4WWQ A;  2MK2 A;  4OHL A;  4OHI A;  3VS2 A;  4H34 A;  1BHF A;  1A1A A;  3HCK A;  2IUH A;  1RPY A;  5IBM A;  1Y1U A;  3VS3 A;  1O4D A;  2CIA A;  1NZL A;  1O4H A;  1GRI A;  3CD3 A;  3MXY A;  2JYQ A;  1AOU F;  1X6C A;  2Y3A B;  1O4B A;  2EL8 A;  5CDW A;  3PS5 A;  1O4L A;  4F5A A;  2OZO A;  1G83 A;  1Y57 A;  3C7I A;  3BUO B;  1KC2 A;  1UUS A;  1JYQ A;  2Y1M A;  4D8K A;  2BBU A;  1O4A A;  4NWF A;  5HKW A;  3IN8 A;  1SPR A;  3BKB A;  2VIF A;  3PSK A;  5DC9 A;  4OHE A;  3TL0 A;  3MAZ A;  1HCS B;  1A09 A;  1O4C A;  4FL2 A;  3CBL A;  4EY0 A;  2DVJ A;  2CRH A;  2PLD A;  1KSW A;  1UUR A;  4M4Z A;  2EU0 A;  2EYY A;  2CBL A;  2CI9 A;  1LUK A;  3BUW B;  2K79 B;  2C9W A;  5BO4 A;  2HDV A;  5GJH A;  1WQU A;  2QMS A;  4OHD A;  3VRP A;  1R1P A;  2EO3 A;  2CS0 A;  3CXL A;  3VRQ A;  5DF6 A;  2C0T A;  1D1Z A;  1R1S A;  2H46 E;  4FL3 A;  1MIL A;  1JWO A;  4A4C A;  1LKK A;  1M27 A;  1A1E A;  1D4T A;  2EO6 A;  4DGX A;  3BUN B;  1KA6 A;  1YVH A;  1B47 A;  2Y1N A;  1D4W A;  1FU5 A;  1O45 A;  3OV1 A;  5DC4 A;  3S8O A;  1BHH B;  2XP1 A;  4NWG A;  1BKM A;  1LUI A;  3S8N A;  1A1B A;  3IMD A;  4K11 A;  2RMX A;  1KA7 A;  1O4E A;  2MC1 A;  3GXX A;  2B3O A;  2SRC A;  2YSX A;  3HIZ B;  2RVF A;  2AOA A;  4K44 A;  3OP0 A;  1AD5 A;  5EG3 B;  1M61 A;  1FHS A;  1OO4 A;  1IS0 A;  1BMB A;  2LCT A;  1QCF A;  2PNA A;  3IN7 A;  4LUE A;  5GJI A;  1O4G A;  3ZNI A;  3VRZ A;  2ETZ A;  1BHH A;  1O4F A;  3OB2 B;  1QAD A;  1NZV A;  1CWE A;  5I6V A;  1O48 A;  1F2F A;  1SPS A;  1TCE A;  2AOB A;  2IZV A;  1ZFP E;  4K2R A;  4H1O A;  1YVL A;  3S9K A;  1R1Q A;  1GHU A;  1TZE E;  3VRR A;  5J3X A;  3VRY A;  1O4K A;  2LQW A;  1LCJ A;  3QWY A;  4FBN A;  4OHH A;  1O47 A;  2HUW A;  1O4P A;  1FBZ A;  2EKX A;  3BUX B;  1O4I A;  3PQZ A;  1CSZ A;  3M7F A;  3T04 A;  1NRV A;  3VS6 A;  4L1B B;  3UF4 A;  1H9O A;  1RQQ C;  3US4 A;  2KK6 A;  4F5B A;  2PNB A;  3VS0 A;  2EYV A;  2LNX A;  3IMJ A;  1FMK A;  2L4K A;  2C0I A;  2HCK A;  3N7Y A;  2DCR A;  1AB2 A;  3KFJ A;  2H8H A;  1AOT F;  1CJ1 A;  1X0N A;  1A07 A;  2IUG A;  5HKY A;  1IJR A;  3GXW A;  1AYD A;  2EOB A;  4JGH A;  1O4R A;  1FBV A;  3PLF B;  1JYR A;  2L3T A;  4JE4 A;  4K45 A;  5EHR A;  3MXC A;  1RJA A;  5AUL A;  2CI8 A;  4X6S A;  3N84 A;  5HKZ A;  5IBS A;  2CR4 A;  2ABL A;  2KNO A;  4U17 A;  3CWG A;  1F1W A;  3OVE A;  3S8L A;  2PLE A;  4E68 A;  3N8M A;  2IUI A;  4ROJ A;  1QG1 E;  1AYC A;  3VRN A;  2ROR A;  3VS4 A;  1BFI A;  1O42 A;  2L6K A;  1LKL A;  2ECD A;  3OB1 B;  4JEG A;  2MRK A;  3QWX X;  4XZ1 A;  1O4M A;  2RSY A;  2C0O A;  2GSB A;  1LCK A;  1FYR A;  2MRJ A;  1BF5 A;  1SKJ A;  1A1C A;  3UYO A;  1MW4 A;  1O44 A;  1CSY A;  1A81 A;  1BM2 A;  1O43 A;  1LUM A;  2HMH A;  1BLK A;  1OPL A;  2DLY A;  4EIH A;  2LNW A;  5AXI A;  1BKL A;  5DC0 B;  4DGP A;  2K7A B;  1O46 A;  1BG1 A;  4TZI A;  1A08 A;  2DLZ A;  2H5K A;  1FU6 A;  1XA6 A;  3VRO A;  3TKZ A;  1BLJ A;  4LUD A;  1K9A A;  1SHD A;  4P9Z A;  4P9V A;  4QSY A;  3GQI B;  3EAC A;  4E93 A;  3VS5 A;  1O4O A;  2SHP A;  1O41 A;  5EEL A;  2AUG A;  1O4N A;  3BUM B;  1JU5 A;  1SHA A;  3K2M A;  1O4Q A;  1AYB A;  3HHM B;  4GL9 E;  5EEQ A;  1X27 A;  1AYA A;  1HCT B;  3VS7 A;  1SHB A;  1OO3 A;  1O49 A;  3PSJ A; 
#chains in the Genus database with same CATH topology
 1O4J A;  4GPL B;  5EHP A;  2PTK A;  4F59 A;  2GE9 A;  4U1P A;  4A4B A;  1JYU A;  2YU7 A;  3WA4 A;  2FO0 A;  2MQI A;  3VGO A;  3EAZ A;  1BFJ A;  1OPK A;  3NHN A;  1LUN A;  2DX0 A;  1P13 A;  2DM0 A;  2EYZ A;  2HDX A;  3PJP A;  5KAZ A;  3PFV A;  1PIC A;  2FCI A;  1CWD L;  3VS1 A;  5D0J A;  2LQN A;  1Z3K A;  1I3Z A;  2OQ1 A;  4XZ0 A;  4GWF A;  4WWQ A;  2MK2 A;  4OHL A;  4OHI A;  3VS2 A;  4H34 A;  1BHF A;  1A1A A;  3HCK A;  2IUH A;  1RPY A;  5IBM A;  1Y1U A;  3VS3 A;  1O4D A;  2CIA A;  1NZL A;  1O4H A;  1GRI A;  3CD3 A;  3MXY A;  2JYQ A;  1AOU F;  1X6C A;  2Y3A B;  1O4B A;  2EL8 A;  5CDW A;  3PS5 A;  1O4L A;  4F5A A;  2OZO A;  1G83 A;  1Y57 A;  3C7I A;  3BUO B;  1KC2 A;  1UUS A;  1JYQ A;  2Y1M A;  4D8K A;  2BBU A;  1O4A A;  4NWF A;  5HKW A;  3IN8 A;  1SPR A;  3BKB A;  2VIF A;  3PSK A;  5DC9 A;  4OHE A;  3TL0 A;  3MAZ A;  1HCS B;  1A09 A;  1O4C A;  4FL2 A;  3CBL A;  4EY0 A;  2DVJ A;  2CRH A;  2PLD A;  1KSW A;  1UUR A;  4M4Z A;  2EU0 A;  2EYY A;  2CBL A;  2CI9 A;  1LUK A;  3BUW B;  2K79 B;  2C9W A;  5BO4 A;  2HDV A;  5GJH A;  1WQU A;  2QMS A;  4OHD A;  3VRP A;  1R1P A;  2EO3 A;  2CS0 A;  3CXL A;  3VRQ A;  5DF6 A;  2C0T A;  1D1Z A;  1R1S A;  2H46 E;  4FL3 A;  1MIL A;  2KGY A;  1JWO A;  4A4C A;  1LKK A;  1M27 A;  1A1E A;  1D4T A;  2EO6 A;  4DGX A;  3BUN B;  1KA6 A;  1YVH A;  1B47 A;  2Y1N A;  1D4W A;  1FU5 A;  1O45 A;  3OV1 A;  5DC4 A;  3S8O A;  1BHH B;  2XP1 A;  4NWG A;  1BKM A;  1LUI A;  3S8N A;  1A1B A;  3IMD A;  4K11 A;  2RMX A;  2LRA A;  1KA7 A;  1O4E A;  2MC1 A;  3GXX A;  2B3O A;  2SRC A;  2YSX A;  3HIZ B;  2RVF A;  2AOA A;  4K44 A;  3OP0 A;  1AD5 A;  5EG3 B;  1M61 A;  1FHS A;  1OO4 A;  1IS0 A;  1BMB A;  2LCT A;  1QCF A;  2PNA A;  3IN7 A;  4LUE A;  5GJI A;  1O4G A;  3ZNI A;  3VRZ A;  2ETZ A;  1BHH A;  1O4F A;  3OB2 B;  1QAD A;  1NZV A;  1CWE A;  5I6V A;  1O48 A;  1F2F A;  1SPS A;  1TCE A;  2AOB A;  2IZV A;  1ZFP E;  4K2R A;  4H1O A;  1YVL A;  3S9K A;  1R1Q A;  1GHU A;  1TZE E;  3VRR A;  5J3X A;  3VRY A;  1O4K A;  3K2T A;  2LQW A;  1LCJ A;  3QWY A;  4FBN A;  4OHH A;  1O47 A;  2HUW A;  1O4P A;  1FBZ A;  2EKX A;  3BUX B;  1O4I A;  3PQZ A;  1CSZ A;  3M7F A;  3T04 A;  1NRV A;  3VS6 A;  4L1B B;  3UF4 A;  1H9O A;  1RQQ C;  3US4 A;  2KK6 A;  4F5B A;  2PNB A;  3VS0 A;  2EYV A;  2LNX A;  3IMJ A;  1FMK A;  2L4K A;  2C0I A;  2HCK A;  3N7Y A;  2DCR A;  1AB2 A;  3KFJ A;  2H8H A;  1AOT F;  1CJ1 A;  1X0N A;  1A07 A;  2IUG A;  5HKY A;  1IJR A;  3GXW A;  1AYD A;  2EOB A;  4JGH A;  1O4R A;  1FBV A;  3PLF B;  1JYR A;  2L3T A;  4JE4 A;  4K45 A;  5EHR A;  3MXC A;  1RJA A;  5AUL A;  2CI8 A;  4X6S A;  3N84 A;  5HKZ A;  5IBS A;  2CR4 A;  2ABL A;  2KNO A;  4U17 A;  3CWG A;  1F1W A;  3OVE A;  3S8L A;  2PLE A;  4E68 A;  3N8M A;  2IUI A;  4ROJ A;  1QG1 E;  1AYC A;  3VRN A;  2ROR A;  3VS4 A;  1BFI A;  1O42 A;  2L6K A;  1LKL A;  2ECD A;  3OB1 B;  4JEG A;  2MRK A;  3QWX X;  4XZ1 A;  1O4M A;  2RSY A;  2C0O A;  2GSB A;  1LCK A;  1FYR A;  2MRJ A;  1BF5 A;  1SKJ A;  1A1C A;  3UYO A;  1MW4 A;  1O44 A;  1CSY A;  1A81 A;  1BM2 A;  1O43 A;  1LUM A;  2HMH A;  1BLK A;  1OPL A;  2DLY A;  4EIH A;  2LNW A;  5AXI A;  1BKL A;  5DC0 B;  4DGP A;  2K7A B;  1O46 A;  1BG1 A;  4TZI A;  1A08 A;  2DLZ A;  2H5K A;  1FU6 A;  1XA6 A;  3VRO A;  3TKZ A;  1BLJ A;  4LUD A;  1K9A A;  1SHD A;  4P9Z A;  4P9V A;  4QSY A;  3GQI B;  3EAC A;  4E93 A;  3VS5 A;  1O4O A;  2SHP A;  1O41 A;  5EEL A;  2AUG A;  1O4N A;  3BUM B;  3LYV A;  1JU5 A;  1SHA A;  3K2M A;  1O4Q A;  1AYB A;  3HHM B;  4GL9 E;  5EEQ A;  1X27 A;  1AYA A;  1HCT B;  3VS7 A;  1SHB A;  1OO3 A;  1O49 A;  3PSJ A; 
#chains in the Genus database with same CATH homology
 1O4J A;  4GPL B;  5EHP A;  2PTK A;  4F59 A;  2GE9 A;  4U1P A;  4A4B A;  1JYU A;  2YU7 A;  3WA4 A;  2FO0 A;  2MQI A;  3VGO A;  3EAZ A;  1BFJ A;  1OPK A;  3NHN A;  1LUN A;  2DX0 A;  1P13 A;  2DM0 A;  2EYZ A;  2HDX A;  3PJP A;  5KAZ A;  3PFV A;  1PIC A;  2FCI A;  1CWD L;  3VS1 A;  5D0J A;  2LQN A;  1Z3K A;  1I3Z A;  2OQ1 A;  4XZ0 A;  4GWF A;  4WWQ A;  2MK2 A;  4OHL A;  4OHI A;  3VS2 A;  4H34 A;  1BHF A;  1A1A A;  3HCK A;  2IUH A;  1RPY A;  5IBM A;  1Y1U A;  3VS3 A;  1O4D A;  2CIA A;  1NZL A;  1O4H A;  1GRI A;  3CD3 A;  3MXY A;  2JYQ A;  1AOU F;  1X6C A;  2Y3A B;  1O4B A;  2EL8 A;  5CDW A;  3PS5 A;  1O4L A;  4F5A A;  2OZO A;  1G83 A;  1Y57 A;  3C7I A;  3BUO B;  1KC2 A;  1UUS A;  1JYQ A;  2Y1M A;  4D8K A;  2BBU A;  1O4A A;  4NWF A;  5HKW A;  3IN8 A;  1SPR A;  3BKB A;  2VIF A;  3PSK A;  5DC9 A;  4OHE A;  3TL0 A;  3MAZ A;  1HCS B;  1A09 A;  1O4C A;  4FL2 A;  3CBL A;  4EY0 A;  2DVJ A;  2CRH A;  2PLD A;  1KSW A;  1UUR A;  4M4Z A;  2EU0 A;  2EYY A;  2CBL A;  2CI9 A;  1LUK A;  3BUW B;  2K79 B;  2C9W A;  5BO4 A;  2HDV A;  5GJH A;  1WQU A;  2QMS A;  4OHD A;  3VRP A;  1R1P A;  2EO3 A;  2CS0 A;  3CXL A;  3VRQ A;  5DF6 A;  2C0T A;  1D1Z A;  1R1S A;  2H46 E;  4FL3 A;  1MIL A;  1JWO A;  4A4C A;  1LKK A;  1M27 A;  1A1E A;  1D4T A;  2EO6 A;  4DGX A;  3BUN B;  1KA6 A;  1YVH A;  1B47 A;  2Y1N A;  1D4W A;  1FU5 A;  1O45 A;  3OV1 A;  5DC4 A;  3S8O A;  1BHH B;  2XP1 A;  4NWG A;  1BKM A;  1LUI A;  3S8N A;  1A1B A;  3IMD A;  4K11 A;  2RMX A;  1KA7 A;  1O4E A;  2MC1 A;  3GXX A;  2B3O A;  2SRC A;  2YSX A;  3HIZ B;  2RVF A;  2AOA A;  4K44 A;  3OP0 A;  1AD5 A;  5EG3 B;  1M61 A;  1FHS A;  1OO4 A;  1IS0 A;  1BMB A;  2LCT A;  1QCF A;  2PNA A;  3IN7 A;  4LUE A;  5GJI A;  1O4G A;  3ZNI A;  3VRZ A;  2ETZ A;  1BHH A;  1O4F A;  3OB2 B;  1QAD A;  1NZV A;  1CWE A;  5I6V A;  1O48 A;  1F2F A;  1SPS A;  1TCE A;  2AOB A;  2IZV A;  1ZFP E;  4K2R A;  4H1O A;  1YVL A;  3S9K A;  1R1Q A;  1GHU A;  1TZE E;  3VRR A;  5J3X A;  3VRY A;  1O4K A;  2LQW A;  1LCJ A;  3QWY A;  4FBN A;  4OHH A;  1O47 A;  2HUW A;  1O4P A;  1FBZ A;  2EKX A;  3BUX B;  1O4I A;  3PQZ A;  1CSZ A;  3M7F A;  3T04 A;  1NRV A;  3VS6 A;  4L1B B;  3UF4 A;  1H9O A;  1RQQ C;  3US4 A;  2KK6 A;  4F5B A;  2PNB A;  3VS0 A;  2EYV A;  2LNX A;  3IMJ A;  1FMK A;  2L4K A;  2C0I A;  2HCK A;  3N7Y A;  2DCR A;  1AB2 A;  3KFJ A;  2H8H A;  1AOT F;  1CJ1 A;  1X0N A;  1A07 A;  2IUG A;  5HKY A;  1IJR A;  3GXW A;  1AYD A;  2EOB A;  4JGH A;  1O4R A;  1FBV A;  3PLF B;  1JYR A;  2L3T A;  4JE4 A;  4K45 A;  5EHR A;  3MXC A;  1RJA A;  5AUL A;  2CI8 A;  4X6S A;  3N84 A;  5HKZ A;  5IBS A;  2CR4 A;  2ABL A;  2KNO A;  4U17 A;  3CWG A;  1F1W A;  3OVE A;  3S8L A;  2PLE A;  4E68 A;  3N8M A;  2IUI A;  4ROJ A;  1QG1 E;  1AYC A;  3VRN A;  2ROR A;  3VS4 A;  1BFI A;  1O42 A;  2L6K A;  1LKL A;  2ECD A;  3OB1 B;  4JEG A;  2MRK A;  3QWX X;  4XZ1 A;  1O4M A;  2RSY A;  2C0O A;  2GSB A;  1LCK A;  1FYR A;  2MRJ A;  1BF5 A;  1SKJ A;  1A1C A;  3UYO A;  1MW4 A;  1O44 A;  1CSY A;  1A81 A;  1BM2 A;  1O43 A;  1LUM A;  2HMH A;  1BLK A;  1OPL A;  2DLY A;  4EIH A;  2LNW A;  5AXI A;  1BKL A;  5DC0 B;  4DGP A;  2K7A B;  1O46 A;  1BG1 A;  4TZI A;  1A08 A;  2DLZ A;  2H5K A;  1FU6 A;  1XA6 A;  3VRO A;  3TKZ A;  1BLJ A;  4LUD A;  1K9A A;  1SHD A;  4P9Z A;  4P9V A;  4QSY A;  3GQI B;  3EAC A;  4E93 A;  3VS5 A;  1O4O A;  2SHP A;  1O41 A;  5EEL A;  2AUG A;  1O4N A;  3BUM B;  1JU5 A;  1SHA A;  3K2M A;  1O4Q A;  1AYB A;  3HHM B;  4GL9 E;  5EEQ A;  1X27 A;  1AYA A;  1HCT B;  3VS7 A;  1SHB A;  1OO3 A;  1O49 A;  3PSJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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