5EG3B

Crystal structure of the activated fgf receptor 2 (fgfr2) kinase domain in complex with the csh2 domain of phospholipase c gamma (plcgamma)
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
113
structure length
113
Chain Sequence
MNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Two FGF Receptor Kinase Molecules Act in Concert to Recruit and Transphosphorylate Phospholipase C gamma.
pubmed doi rcsb
molecule tags Transferase/hydrolase
source organism Homo sapiens
molecule keywords Fibroblast growth factor receptor 2
total genus 26
structure length 113
sequence length 113
ec nomenclature ec 3.1.4.11: Phosphoinositide phospholipase C.
pdb deposition date 2015-10-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00017 SH2 SH2 domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.505.10 Alpha Beta 2-Layer Sandwich SHC Adaptor Protein SH2 domain 5eg3B00
3VS0A 1BFIA 1LUIA 1SHDA 1O47A 4LUDA 1BHHA 2PLEA 1G83A 1O4GA 2SRCA 2L3TA 2CRHA 1PICA 3UF4A 2H5KA 3CD3A 5EEQA 1LCJA 2EKXA 2VIFA 3MAZA 1O4BA 1YVHA 1O4DA 2IZVA 2YU7A 4X6SA 2EYVA 3PSJA 1Y57A 4FL2A 1F2FA 1D4TA 2HMHA 2AOBA 2C9WA 5HKYA 3VRZA 1IJRA 2KK6A 3VRRA 1JYRA 4EY0A 1BLJA 1X0NA 2LQWA 1O43A 1JU5A 3C7IA 3VROA 4WWQA 3VS7A 4FL3A 4TZIA 3BKBA 1H9OA 4ROJA 1JYQA 4P9ZA 1WQUA 2DCRA 3MXYA 4D8KA 2QMSA 2DM0A 5EHRA 1F1WA 3VRPA 1O4JA 4NWFA 1KSWA 2CIAA 2EO3A 1P13A 3KFJA 1O4HA 1M27A 2AUGA 5GJHA 2XP1A 2RSYA 3K2MA 2DLYA 2RORA 1R1PA 4EIHA 3OB1B 1A1AA 3PQZA 1UURA 5KAZA 3ZNIA 2GE9A 1FBVA 3VS3A 4DGXA 5DC4A 3TKZA 4U17A 2EOBA 3OB2B 3BUXB 1OO4A 1IS0A 4A4CA 1O44A 1HCTB 3T04A 2YSXA 2CS0A 2C0IA 3M7FA 1O4EA 2CI9A 3PLFB 3VS2A 2EO6A 2DX0A 3TL0A 3HHMB 2DLZA 3VRQA 1LKKA 1CWDL 1LCKA 1QG1E 1FBZA 1O4RA 4JGHA 2K79B 3VGOA 2EL8A 3HIZB 1A07A 2EYZA 2GSBA 1R1SA 3VS1A 3N8MA 1XA6A 1BHHB 1JWOA 3PFVA 1O4AA 1KA7A 1QCFA 2CI8A 1FU5A 3BUNB 4L1BB 1RPYA 1O4CA 2ABLA 1O4OA 2PLDA 2LNXA 4OHHA 1BHFA 4F5BA 5IBMA 4K11A 3S8OA 4F59A 1O4KA 5EHPA 1AOUF 2Y1MA 2MQIA 2HCKA 1O4PA 1O4LA 3S9KA 1BMBA 2FO0A 1I3ZA 1LUMA 2B3OA 4H34A 1X6CA 3VRNA 4K44A 4QSYA 1RQQC 3VS5A 1SPRA 2IUIA 2LCTA 2ECDA 1Y1UA 4H1OA 4XZ0A 3UYOA 2HDXA 3IN7A 2Y1NA 1QADA 4F5AA 3N84A 4OHIA 5BO4A 1NZLA 1OO3A 1O4NA 4NWGA 1A08A 1O4QA 2HUWA 1NRVA 3US4A 3CXLA 2OQ1A 3NHNA 1O45A 4P9VA 1TZEE 4A4BA 3EAZA 3PS5A 2RMXA 5HKWA 1SHBA 4E68A 2AOAA 4FBNA 1A1BA 1OPLA 2BBUA 5HKZA 4JEGA 3PJPA 3WA4A 1X27A 1AYAA 2H8HA 1AB2A 1AYCA 1O42A 1R1QA 5EELA 1NZVA 1O41A 1LUKA 1TCEA 5GJIA 1CJ1A 3VS6A 1KC2A 2MC1A 2FCIA 4JE4A 3QWYA 1AYBA 1BG1A 1JYUA 1BM2A 1B47A 4DGPA 3HCKA 1Z3KA 5DF6A 2RVFA 5IBSA 1FHSA 2C0OA 1GHUA 3IN8A 1CWEA 3OVEA 4LUEA 3OP0A 2CBLA 1D4WA 3VS4A 2HDVA 1SPSA 3CBLA 3VRYA 1O4MA 1BF5A 3MXCA 1AOTF 4E93A 4K45A 5I6VA 2OZOA 4OHLA 4U1PA 4OHEA 1ZFPE 1LKLA 1KA6A 3CWGA 1A81A 3GQIB 3GXXA 2MRKA 3GXWA 5AULA 2EYYA 2IUHA 5DC9A 5DC0B 2PTKA 5D0JA 1MILA 4OHDA 1MW4A 1O49A 3IMDA 2L6KA 2PNAA 2DVJA 3BUMB 4XZ1A 1AYDA 1CSYA 2C0TA 2CR4A 5EG3B 2JYQA 1SKJA 2Y3AB 4M4ZA 1A1EA 1K9AA 2IUGA 2K7AB 1RJAA 1BFJA 1FU6A 1LUNA 3EACA 1O4FA 3BUOB 3IMJA 3N7YA 3S8NA 1FMKA 1M61A 2EU0A 2SHPA 1O46A 1OPKA 3QWXX 2LQNA 1UUSA 1A09A 1A1CA 4GL9E 2LNWA 2MK2A 4K2RA 5AXIA 1YVLA 1O48A 3S8LA 1O4IA 1FYRA 2MRJA 4GWFA 2PNBA 1GRIA 1BLKA 3BUWB 2H46E 2ETZA 5J3XA 1AD5A 1CSZA 2L4KA 1BKMA 3PSKA 3OV1A 1BKLA 1D1ZA 4GPLB 2KNOA 5CDWA 1SHAA 1HCSB
chains in the Genus database with same CATH superfamily
3VS0A 1BFIA 1LUIA 1SHDA 1O47A 4LUDA 1BHHA 2PLEA 1G83A 1O4GA 2SRCA 2L3TA 2CRHA 1PICA 3UF4A 2H5KA 3CD3A 5EEQA 1LCJA 2EKXA 2VIFA 3MAZA 1O4BA 1YVHA 1O4DA 2IZVA 2YU7A 4X6SA 2EYVA 3PSJA 1Y57A 4FL2A 1F2FA 1D4TA 2HMHA 2AOBA 2C9WA 5HKYA 3VRZA 1IJRA 2KK6A 3VRRA 1JYRA 4EY0A 1BLJA 1X0NA 2LQWA 1O43A 1JU5A 3C7IA 3VROA 4WWQA 3VS7A 4FL3A 4TZIA 3BKBA 1H9OA 4ROJA 1JYQA 4P9ZA 1WQUA 2DCRA 3MXYA 4D8KA 2QMSA 2DM0A 5EHRA 1F1WA 3VRPA 1O4JA 4NWFA 1KSWA 2CIAA 2EO3A 1P13A 3KFJA 1O4HA 1M27A 2AUGA 5GJHA 2XP1A 2RSYA 3K2MA 2DLYA 2RORA 1R1PA 4EIHA 3OB1B 1A1AA 3PQZA 1UURA 5KAZA 3ZNIA 2GE9A 1FBVA 3VS3A 4DGXA 5DC4A 3TKZA 4U17A 2EOBA 3OB2B 3BUXB 1OO4A 1IS0A 4A4CA 1O44A 1HCTB 3T04A 2YSXA 2CS0A 2C0IA 3M7FA 1O4EA 2CI9A 3PLFB 3VS2A 2EO6A 2DX0A 3TL0A 3HHMB 2DLZA 3VRQA 1LKKA 1CWDL 1LCKA 1QG1E 1FBZA 1O4RA 4JGHA 2K79B 3VGOA 2EL8A 3HIZB 1A07A 2EYZA 2GSBA 1R1SA 3VS1A 3N8MA 1XA6A 1BHHB 1JWOA 3PFVA 1O4AA 1KA7A 1QCFA 2CI8A 1FU5A 3BUNB 4L1BB 1RPYA 1O4CA 2ABLA 1O4OA 2PLDA 2LNXA 4OHHA 1BHFA 4F5BA 5IBMA 4K11A 3S8OA 4F59A 1O4KA 5EHPA 1AOUF 2Y1MA 2MQIA 2HCKA 3LYVA 1O4PA 1O4LA 3S9KA 1BMBA 2FO0A 1I3ZA 1LUMA 2B3OA 4H34A 1X6CA 3VRNA 4K44A 4QSYA 1RQQC 3VS5A 1SPRA 2IUIA 2LCTA 2ECDA 1Y1UA 4H1OA 4XZ0A 3UYOA 2HDXA 3IN7A 2Y1NA 1QADA 4F5AA 3N84A 4OHIA 5BO4A 1NZLA 1OO3A 1O4NA 4NWGA 1A08A 1O4QA 2HUWA 1NRVA 3K2TA 3US4A 3CXLA 2OQ1A 3NHNA 1O45A 4P9VA 1TZEE 4A4BA 3EAZA 3PS5A 2RMXA 5HKWA 1SHBA 4E68A 2AOAA 4FBNA 1A1BA 1OPLA 2BBUA 2LRAA 5HKZA 4JEGA 3PJPA 3WA4A 1X27A 1AYAA 2H8HA 1AB2A 1AYCA 1O42A 1R1QA 5EELA 1NZVA 1O41A 1LUKA 1TCEA 5GJIA 1CJ1A 3VS6A 1KC2A 2MC1A 2FCIA 4JE4A 3QWYA 1AYBA 1BG1A 1JYUA 1BM2A 1B47A 4DGPA 3HCKA 1Z3KA 5DF6A 2RVFA 5IBSA 1FHSA 2C0OA 1GHUA 3IN8A 1CWEA 3OVEA 4LUEA 3OP0A 2KGYA 2CBLA 1D4WA 3VS4A 2HDVA 1SPSA 3CBLA 3VRYA 1O4MA 1BF5A 3MXCA 1AOTF 4E93A 4K45A 5I6VA 2OZOA 4OHLA 4U1PA 4OHEA 1ZFPE 1LKLA 1KA6A 3CWGA 1A81A 3GQIB 3GXXA 2MRKA 3GXWA 5AULA 2EYYA 2IUHA 5DC9A 5DC0B 2PTKA 5D0JA 1MILA 4OHDA 1MW4A 1O49A 3IMDA 2L6KA 2PNAA 2DVJA 3BUMB 4XZ1A 1AYDA 1CSYA 2C0TA 2CR4A 5EG3B 2JYQA 1SKJA 2Y3AB 4M4ZA 1A1EA 1K9AA 2IUGA 2K7AB 1RJAA 1BFJA 1FU6A 1LUNA 3EACA 1O4FA 3BUOB 3IMJA 3N7YA 3S8NA 1FMKA 1M61A 2EU0A 2SHPA 1O46A 1OPKA 3QWXX 2LQNA 1UUSA 1A09A 1A1CA 4GL9E 2LNWA 2MK2A 4K2RA 5AXIA 1YVLA 1O48A 3S8LA 1O4IA 1FYRA 2MRJA 4GWFA 2PNBA 1GRIA 1BLKA 3BUWB 2H46E 2ETZA 5J3XA 1AD5A 1CSZA 2L4KA 1BKMA 3PSKA 3OV1A 1BKLA 1D1ZA 4GPLB 2KNOA 5CDWA 1SHAA 1HCSB
chains in the Genus database with same CATH topology
3VS0A 1BFIA 1LUIA 1SHDA 1O47A 4LUDA 1BHHA 2PLEA 1G83A 1O4GA 2SRCA 2L3TA 2CRHA 1PICA 3UF4A 2H5KA 3CD3A 5EEQA 1LCJA 2EKXA 2VIFA 3MAZA 1O4BA 1YVHA 1O4DA 2IZVA 2YU7A 4X6SA 2EYVA 3PSJA 1Y57A 4FL2A 1F2FA 1D4TA 2HMHA 2AOBA 2C9WA 5HKYA 3VRZA 1IJRA 2KK6A 3VRRA 1JYRA 4EY0A 1BLJA 1X0NA 2LQWA 1O43A 1JU5A 3C7IA 3VROA 4WWQA 3VS7A 4FL3A 4TZIA 3BKBA 1H9OA 4ROJA 1JYQA 4P9ZA 1WQUA 2DCRA 3MXYA 4D8KA 2QMSA 2DM0A 5EHRA 1F1WA 3VRPA 1O4JA 4NWFA 1KSWA 2CIAA 2EO3A 1P13A 3KFJA 1O4HA 1M27A 2AUGA 5GJHA 2XP1A 2RSYA 3K2MA 2DLYA 2RORA 1R1PA 4EIHA 3OB1B 1A1AA 3PQZA 1UURA 5KAZA 3ZNIA 2GE9A 1FBVA 3VS3A 4DGXA 5DC4A 3TKZA 4U17A 2EOBA 3OB2B 3BUXB 1OO4A 1IS0A 4A4CA 1O44A 1HCTB 3T04A 2YSXA 2CS0A 2C0IA 3M7FA 1O4EA 2CI9A 3PLFB 3VS2A 2EO6A 2DX0A 3TL0A 3HHMB 2DLZA 3VRQA 1LKKA 1CWDL 1LCKA 1QG1E 1FBZA 1O4RA 4JGHA 2K79B 3VGOA 2EL8A 3HIZB 1A07A 2EYZA 2GSBA 1R1SA 3VS1A 3N8MA 1XA6A 1BHHB 1JWOA 3PFVA 1O4AA 1KA7A 1QCFA 2CI8A 1FU5A 3BUNB 4L1BB 1RPYA 1O4CA 2ABLA 1O4OA 2PLDA 2LNXA 4OHHA 1BHFA 4F5BA 5IBMA 4K11A 3S8OA 4F59A 1O4KA 5EHPA 1AOUF 2Y1MA 2MQIA 2HCKA 1O4PA 1O4LA 3S9KA 1BMBA 2FO0A 1I3ZA 1LUMA 2B3OA 4H34A 1X6CA 3VRNA 4K44A 4QSYA 1RQQC 3VS5A 1SPRA 2IUIA 2LCTA 2ECDA 1Y1UA 4H1OA 4XZ0A 3UYOA 2HDXA 3IN7A 2Y1NA 1QADA 4F5AA 3N84A 4OHIA 5BO4A 1NZLA 1OO3A 1O4NA 4NWGA 1A08A 1O4QA 2HUWA 1NRVA 3US4A 3CXLA 2OQ1A 3NHNA 1O45A 4P9VA 1TZEE 4A4BA 3EAZA 3PS5A 2RMXA 5HKWA 1SHBA 4E68A 2AOAA 4FBNA 1A1BA 1OPLA 2BBUA 5HKZA 4JEGA 3PJPA 3WA4A 1X27A 1AYAA 2H8HA 1AB2A 1AYCA 1O42A 1R1QA 5EELA 1NZVA 1O41A 1LUKA 1TCEA 5GJIA 1CJ1A 3VS6A 1KC2A 2MC1A 2FCIA 4JE4A 3QWYA 1AYBA 1BG1A 1JYUA 1BM2A 1B47A 4DGPA 3HCKA 1Z3KA 5DF6A 2RVFA 5IBSA 1FHSA 2C0OA 1GHUA 3IN8A 1CWEA 3OVEA 4LUEA 3OP0A 2CBLA 1D4WA 3VS4A 2HDVA 1SPSA 3CBLA 3VRYA 1O4MA 1BF5A 3MXCA 1AOTF 4E93A 4K45A 5I6VA 2OZOA 4OHLA 4U1PA 4OHEA 1ZFPE 1LKLA 1KA6A 3CWGA 1A81A 3GQIB 3GXXA 2MRKA 3GXWA 5AULA 2EYYA 2IUHA 5DC9A 5DC0B 2PTKA 5D0JA 1MILA 4OHDA 1MW4A 1O49A 3IMDA 2L6KA 2PNAA 2DVJA 3BUMB 4XZ1A 1AYDA 1CSYA 2C0TA 2CR4A 5EG3B 2JYQA 1SKJA 2Y3AB 4M4ZA 1A1EA 1K9AA 2IUGA 2K7AB 1RJAA 1BFJA 1FU6A 1LUNA 3EACA 1O4FA 3BUOB 3IMJA 3N7YA 3S8NA 1FMKA 1M61A 2EU0A 2SHPA 1O46A 1OPKA 3QWXX 2LQNA 1UUSA 1A09A 1A1CA 4GL9E 2LNWA 2MK2A 4K2RA 5AXIA 1YVLA 1O48A 3S8LA 1O4IA 1FYRA 2MRJA 4GWFA 2PNBA 1GRIA 1BLKA 3BUWB 2H46E 2ETZA 5J3XA 1AD5A 1CSZA 2L4KA 1BKMA 3PSKA 3OV1A 1BKLA 1D1ZA 4GPLB 2KNOA 5CDWA 1SHAA 1HCSB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VS0 A;  1BFI A;  1LUI A;  1SHD A;  1O47 A;  4LUD A;  1BHH A;  2PLE A;  1G83 A;  1O4G A;  2SRC A;  2L3T A;  2CRH A;  1PIC A;  3UF4 A;  2H5K A;  3CD3 A;  5EEQ A;  1LCJ A;  2EKX A;  2VIF A;  3MAZ A;  1O4B A;  1YVH A;  1O4D A;  2IZV A;  2YU7 A;  4X6S A;  2EYV A;  3PSJ A;  1Y57 A;  4FL2 A;  1F2F A;  1D4T A;  2HMH A;  2AOB A;  2C9W A;  5HKY A;  3VRZ A;  1IJR A;  2KK6 A;  3VRR A;  1JYR A;  4EY0 A;  1BLJ A;  1X0N A;  2LQW A;  1O43 A;  1JU5 A;  3C7I A;  3VRO A;  4WWQ A;  3VS7 A;  4FL3 A;  4TZI A;  3BKB A;  1H9O A;  4ROJ A;  1JYQ A;  4P9Z A;  1WQU A;  2DCR A;  3MXY A;  4D8K A;  2QMS A;  2DM0 A;  5EHR A;  1F1W A;  3VRP A;  1O4J A;  4NWF A;  1KSW A;  2CIA A;  2EO3 A;  1P13 A;  3KFJ A;  1O4H A;  1M27 A;  2AUG A;  5GJH A;  2XP1 A;  2RSY A;  3K2M A;  2DLY A;  2ROR A;  1R1P A;  4EIH A;  3OB1 B;  1A1A A;  3PQZ A;  1UUR A;  5KAZ A;  3ZNI A;  2GE9 A;  1FBV A;  3VS3 A;  4DGX A;  5DC4 A;  3TKZ A;  4U17 A;  2EOB A;  3OB2 B;  3BUX B;  1OO4 A;  1IS0 A;  4A4C A;  1O44 A;  1HCT B;  3T04 A;  2YSX A;  2CS0 A;  2C0I A;  3M7F A;  1O4E A;  2CI9 A;  3PLF B;  3VS2 A;  2EO6 A;  2DX0 A;  3TL0 A;  3HHM B;  2DLZ A;  3VRQ A;  1LKK A;  1CWD L;  1LCK A;  1QG1 E;  1FBZ A;  1O4R A;  4JGH A;  2K79 B;  3VGO A;  2EL8 A;  3HIZ B;  1A07 A;  2EYZ A;  2GSB A;  1R1S A;  3VS1 A;  3N8M A;  1XA6 A;  1BHH B;  1JWO A;  3PFV A;  1O4A A;  1KA7 A;  1QCF A;  2CI8 A;  1FU5 A;  3BUN B;  4L1B B;  1RPY A;  1O4C A;  2ABL A;  1O4O A;  2PLD A;  2LNX A;  4OHH A;  1BHF A;  4F5B A;  5IBM A;  4K11 A;  3S8O A;  4F59 A;  1O4K A;  5EHP A;  1AOU F;  2Y1M A;  2MQI A;  2HCK A;  1O4P A;  1O4L A;  3S9K A;  1BMB A;  2FO0 A;  1I3Z A;  1LUM A;  2B3O A;  4H34 A;  1X6C A;  3VRN A;  4K44 A;  4QSY A;  1RQQ C;  3VS5 A;  1SPR A;  2IUI A;  2LCT A;  2ECD A;  1Y1U A;  4H1O A;  4XZ0 A;  3UYO A;  2HDX A;  3IN7 A;  2Y1N A;  1QAD A;  4F5A A;  3N84 A;  4OHI A;  5BO4 A;  1NZL A;  1OO3 A;  1O4N A;  4NWG A;  1A08 A;  1O4Q A;  2HUW A;  1NRV A;  3US4 A;  3CXL A;  2OQ1 A;  3NHN A;  1O45 A;  4P9V A;  1TZE E;  4A4B A;  3EAZ A;  3PS5 A;  2RMX A;  5HKW A;  1SHB A;  4E68 A;  2AOA A;  4FBN A;  1A1B A;  1OPL A;  2BBU A;  5HKZ A;  4JEG A;  3PJP A;  3WA4 A;  1X27 A;  1AYA A;  2H8H A;  1AB2 A;  1AYC A;  1O42 A;  1R1Q A;  5EEL A;  1NZV A;  1O41 A;  1LUK A;  1TCE A;  5GJI A;  1CJ1 A;  3VS6 A;  1KC2 A;  2MC1 A;  2FCI A;  4JE4 A;  3QWY A;  1AYB A;  1BG1 A;  1JYU A;  1BM2 A;  1B47 A;  4DGP A;  3HCK A;  1Z3K A;  5DF6 A;  2RVF A;  5IBS A;  1FHS A;  2C0O A;  1GHU A;  3IN8 A;  1CWE A;  3OVE A;  4LUE A;  3OP0 A;  2CBL A;  1D4W A;  3VS4 A;  2HDV A;  1SPS A;  3CBL A;  3VRY A;  1O4M A;  1BF5 A;  3MXC A;  1AOT F;  4E93 A;  4K45 A;  5I6V A;  2OZO A;  4OHL A;  4U1P A;  4OHE A;  1ZFP E;  1LKL A;  1KA6 A;  3CWG A;  1A81 A;  3GQI B;  3GXX A;  2MRK A;  3GXW A;  5AUL A;  2EYY A;  2IUH A;  5DC9 A;  5DC0 B;  2PTK A;  5D0J A;  1MIL A;  4OHD A;  1MW4 A;  1O49 A;  3IMD A;  2L6K A;  2PNA A;  2DVJ A;  3BUM B;  4XZ1 A;  1AYD A;  1CSY A;  2C0T A;  2CR4 A;  5EG3 B;  2JYQ A;  1SKJ A;  2Y3A B;  4M4Z A;  1A1E A;  1K9A A;  2IUG A;  2K7A B;  1RJA A;  1BFJ A;  1FU6 A;  1LUN A;  3EAC A;  1O4F A;  3BUO B;  3IMJ A;  3N7Y A;  3S8N A;  1FMK A;  1M61 A;  2EU0 A;  2SHP A;  1O46 A;  1OPK A;  3QWX X;  2LQN A;  1UUS A;  1A09 A;  1A1C A;  4GL9 E;  2LNW A;  2MK2 A;  4K2R A;  5AXI A;  1YVL A;  1O48 A;  3S8L A;  1O4I A;  1FYR A;  2MRJ A;  4GWF A;  2PNB A;  1GRI A;  1BLK A;  3BUW B;  2H46 E;  2ETZ A;  5J3X A;  1AD5 A;  1CSZ A;  2L4K A;  1BKM A;  3PSK A;  3OV1 A;  1BKL A;  1D1Z A;  4GPL B;  2KNO A;  5CDW A;  1SHA A;  1HCS B; 
#chains in the Genus database with same CATH topology
 3VS0 A;  1BFI A;  1LUI A;  1SHD A;  1O47 A;  4LUD A;  1BHH A;  2PLE A;  1G83 A;  1O4G A;  2SRC A;  2L3T A;  2CRH A;  1PIC A;  3UF4 A;  2H5K A;  3CD3 A;  5EEQ A;  1LCJ A;  2EKX A;  2VIF A;  3MAZ A;  1O4B A;  1YVH A;  1O4D A;  2IZV A;  2YU7 A;  4X6S A;  2EYV A;  3PSJ A;  1Y57 A;  4FL2 A;  1F2F A;  1D4T A;  2HMH A;  2AOB A;  2C9W A;  5HKY A;  3VRZ A;  1IJR A;  2KK6 A;  3VRR A;  1JYR A;  4EY0 A;  1BLJ A;  1X0N A;  2LQW A;  1O43 A;  1JU5 A;  3C7I A;  3VRO A;  4WWQ A;  3VS7 A;  4FL3 A;  4TZI A;  3BKB A;  1H9O A;  4ROJ A;  1JYQ A;  4P9Z A;  1WQU A;  2DCR A;  3MXY A;  4D8K A;  2QMS A;  2DM0 A;  5EHR A;  1F1W A;  3VRP A;  1O4J A;  4NWF A;  1KSW A;  2CIA A;  2EO3 A;  1P13 A;  3KFJ A;  1O4H A;  1M27 A;  2AUG A;  5GJH A;  2XP1 A;  2RSY A;  3K2M A;  2DLY A;  2ROR A;  1R1P A;  4EIH A;  3OB1 B;  1A1A A;  3PQZ A;  1UUR A;  5KAZ A;  3ZNI A;  2GE9 A;  1FBV A;  3VS3 A;  4DGX A;  5DC4 A;  3TKZ A;  4U17 A;  2EOB A;  3OB2 B;  3BUX B;  1OO4 A;  1IS0 A;  4A4C A;  1O44 A;  1HCT B;  3T04 A;  2YSX A;  2CS0 A;  2C0I A;  3M7F A;  1O4E A;  2CI9 A;  3PLF B;  3VS2 A;  2EO6 A;  2DX0 A;  3TL0 A;  3HHM B;  2DLZ A;  3VRQ A;  1LKK A;  1CWD L;  1LCK A;  1QG1 E;  1FBZ A;  1O4R A;  4JGH A;  2K79 B;  3VGO A;  2EL8 A;  3HIZ B;  1A07 A;  2EYZ A;  2GSB A;  1R1S A;  3VS1 A;  3N8M A;  1XA6 A;  1BHH B;  1JWO A;  3PFV A;  1O4A A;  1KA7 A;  1QCF A;  2CI8 A;  1FU5 A;  3BUN B;  4L1B B;  1RPY A;  1O4C A;  2ABL A;  1O4O A;  2PLD A;  2LNX A;  4OHH A;  1BHF A;  4F5B A;  5IBM A;  4K11 A;  3S8O A;  4F59 A;  1O4K A;  5EHP A;  1AOU F;  2Y1M A;  2MQI A;  2HCK A;  3LYV A;  1O4P A;  1O4L A;  3S9K A;  1BMB A;  2FO0 A;  1I3Z A;  1LUM A;  2B3O A;  4H34 A;  1X6C A;  3VRN A;  4K44 A;  4QSY A;  1RQQ C;  3VS5 A;  1SPR A;  2IUI A;  2LCT A;  2ECD A;  1Y1U A;  4H1O A;  4XZ0 A;  3UYO A;  2HDX A;  3IN7 A;  2Y1N A;  1QAD A;  4F5A A;  3N84 A;  4OHI A;  5BO4 A;  1NZL A;  1OO3 A;  1O4N A;  4NWG A;  1A08 A;  1O4Q A;  2HUW A;  1NRV A;  3K2T A;  3US4 A;  3CXL A;  2OQ1 A;  3NHN A;  1O45 A;  4P9V A;  1TZE E;  4A4B A;  3EAZ A;  3PS5 A;  2RMX A;  5HKW A;  1SHB A;  4E68 A;  2AOA A;  4FBN A;  1A1B A;  1OPL A;  2BBU A;  2LRA A;  5HKZ A;  4JEG A;  3PJP A;  3WA4 A;  1X27 A;  1AYA A;  2H8H A;  1AB2 A;  1AYC A;  1O42 A;  1R1Q A;  5EEL A;  1NZV A;  1O41 A;  1LUK A;  1TCE A;  5GJI A;  1CJ1 A;  3VS6 A;  1KC2 A;  2MC1 A;  2FCI A;  4JE4 A;  3QWY A;  1AYB A;  1BG1 A;  1JYU A;  1BM2 A;  1B47 A;  4DGP A;  3HCK A;  1Z3K A;  5DF6 A;  2RVF A;  5IBS A;  1FHS A;  2C0O A;  1GHU A;  3IN8 A;  1CWE A;  3OVE A;  4LUE A;  3OP0 A;  2KGY A;  2CBL A;  1D4W A;  3VS4 A;  2HDV A;  1SPS A;  3CBL A;  3VRY A;  1O4M A;  1BF5 A;  3MXC A;  1AOT F;  4E93 A;  4K45 A;  5I6V A;  2OZO A;  4OHL A;  4U1P A;  4OHE A;  1ZFP E;  1LKL A;  1KA6 A;  3CWG A;  1A81 A;  3GQI B;  3GXX A;  2MRK A;  3GXW A;  5AUL A;  2EYY A;  2IUH A;  5DC9 A;  5DC0 B;  2PTK A;  5D0J A;  1MIL A;  4OHD A;  1MW4 A;  1O49 A;  3IMD A;  2L6K A;  2PNA A;  2DVJ A;  3BUM B;  4XZ1 A;  1AYD A;  1CSY A;  2C0T A;  2CR4 A;  5EG3 B;  2JYQ A;  1SKJ A;  2Y3A B;  4M4Z A;  1A1E A;  1K9A A;  2IUG A;  2K7A B;  1RJA A;  1BFJ A;  1FU6 A;  1LUN A;  3EAC A;  1O4F A;  3BUO B;  3IMJ A;  3N7Y A;  3S8N A;  1FMK A;  1M61 A;  2EU0 A;  2SHP A;  1O46 A;  1OPK A;  3QWX X;  2LQN A;  1UUS A;  1A09 A;  1A1C A;  4GL9 E;  2LNW A;  2MK2 A;  4K2R A;  5AXI A;  1YVL A;  1O48 A;  3S8L A;  1O4I A;  1FYR A;  2MRJ A;  4GWF A;  2PNB A;  1GRI A;  1BLK A;  3BUW B;  2H46 E;  2ETZ A;  5J3X A;  1AD5 A;  1CSZ A;  2L4K A;  1BKM A;  3PSK A;  3OV1 A;  1BKL A;  1D1Z A;  4GPL B;  2KNO A;  5CDW A;  1SHA A;  1HCS B; 
#chains in the Genus database with same CATH homology
 3VS0 A;  1BFI A;  1LUI A;  1SHD A;  1O47 A;  4LUD A;  1BHH A;  2PLE A;  1G83 A;  1O4G A;  2SRC A;  2L3T A;  2CRH A;  1PIC A;  3UF4 A;  2H5K A;  3CD3 A;  5EEQ A;  1LCJ A;  2EKX A;  2VIF A;  3MAZ A;  1O4B A;  1YVH A;  1O4D A;  2IZV A;  2YU7 A;  4X6S A;  2EYV A;  3PSJ A;  1Y57 A;  4FL2 A;  1F2F A;  1D4T A;  2HMH A;  2AOB A;  2C9W A;  5HKY A;  3VRZ A;  1IJR A;  2KK6 A;  3VRR A;  1JYR A;  4EY0 A;  1BLJ A;  1X0N A;  2LQW A;  1O43 A;  1JU5 A;  3C7I A;  3VRO A;  4WWQ A;  3VS7 A;  4FL3 A;  4TZI A;  3BKB A;  1H9O A;  4ROJ A;  1JYQ A;  4P9Z A;  1WQU A;  2DCR A;  3MXY A;  4D8K A;  2QMS A;  2DM0 A;  5EHR A;  1F1W A;  3VRP A;  1O4J A;  4NWF A;  1KSW A;  2CIA A;  2EO3 A;  1P13 A;  3KFJ A;  1O4H A;  1M27 A;  2AUG A;  5GJH A;  2XP1 A;  2RSY A;  3K2M A;  2DLY A;  2ROR A;  1R1P A;  4EIH A;  3OB1 B;  1A1A A;  3PQZ A;  1UUR A;  5KAZ A;  3ZNI A;  2GE9 A;  1FBV A;  3VS3 A;  4DGX A;  5DC4 A;  3TKZ A;  4U17 A;  2EOB A;  3OB2 B;  3BUX B;  1OO4 A;  1IS0 A;  4A4C A;  1O44 A;  1HCT B;  3T04 A;  2YSX A;  2CS0 A;  2C0I A;  3M7F A;  1O4E A;  2CI9 A;  3PLF B;  3VS2 A;  2EO6 A;  2DX0 A;  3TL0 A;  3HHM B;  2DLZ A;  3VRQ A;  1LKK A;  1CWD L;  1LCK A;  1QG1 E;  1FBZ A;  1O4R A;  4JGH A;  2K79 B;  3VGO A;  2EL8 A;  3HIZ B;  1A07 A;  2EYZ A;  2GSB A;  1R1S A;  3VS1 A;  3N8M A;  1XA6 A;  1BHH B;  1JWO A;  3PFV A;  1O4A A;  1KA7 A;  1QCF A;  2CI8 A;  1FU5 A;  3BUN B;  4L1B B;  1RPY A;  1O4C A;  2ABL A;  1O4O A;  2PLD A;  2LNX A;  4OHH A;  1BHF A;  4F5B A;  5IBM A;  4K11 A;  3S8O A;  4F59 A;  1O4K A;  5EHP A;  1AOU F;  2Y1M A;  2MQI A;  2HCK A;  1O4P A;  1O4L A;  3S9K A;  1BMB A;  2FO0 A;  1I3Z A;  1LUM A;  2B3O A;  4H34 A;  1X6C A;  3VRN A;  4K44 A;  4QSY A;  1RQQ C;  3VS5 A;  1SPR A;  2IUI A;  2LCT A;  2ECD A;  1Y1U A;  4H1O A;  4XZ0 A;  3UYO A;  2HDX A;  3IN7 A;  2Y1N A;  1QAD A;  4F5A A;  3N84 A;  4OHI A;  5BO4 A;  1NZL A;  1OO3 A;  1O4N A;  4NWG A;  1A08 A;  1O4Q A;  2HUW A;  1NRV A;  3US4 A;  3CXL A;  2OQ1 A;  3NHN A;  1O45 A;  4P9V A;  1TZE E;  4A4B A;  3EAZ A;  3PS5 A;  2RMX A;  5HKW A;  1SHB A;  4E68 A;  2AOA A;  4FBN A;  1A1B A;  1OPL A;  2BBU A;  5HKZ A;  4JEG A;  3PJP A;  3WA4 A;  1X27 A;  1AYA A;  2H8H A;  1AB2 A;  1AYC A;  1O42 A;  1R1Q A;  5EEL A;  1NZV A;  1O41 A;  1LUK A;  1TCE A;  5GJI A;  1CJ1 A;  3VS6 A;  1KC2 A;  2MC1 A;  2FCI A;  4JE4 A;  3QWY A;  1AYB A;  1BG1 A;  1JYU A;  1BM2 A;  1B47 A;  4DGP A;  3HCK A;  1Z3K A;  5DF6 A;  2RVF A;  5IBS A;  1FHS A;  2C0O A;  1GHU A;  3IN8 A;  1CWE A;  3OVE A;  4LUE A;  3OP0 A;  2CBL A;  1D4W A;  3VS4 A;  2HDV A;  1SPS A;  3CBL A;  3VRY A;  1O4M A;  1BF5 A;  3MXC A;  1AOT F;  4E93 A;  4K45 A;  5I6V A;  2OZO A;  4OHL A;  4U1P A;  4OHE A;  1ZFP E;  1LKL A;  1KA6 A;  3CWG A;  1A81 A;  3GQI B;  3GXX A;  2MRK A;  3GXW A;  5AUL A;  2EYY A;  2IUH A;  5DC9 A;  5DC0 B;  2PTK A;  5D0J A;  1MIL A;  4OHD A;  1MW4 A;  1O49 A;  3IMD A;  2L6K A;  2PNA A;  2DVJ A;  3BUM B;  4XZ1 A;  1AYD A;  1CSY A;  2C0T A;  2CR4 A;  5EG3 B;  2JYQ A;  1SKJ A;  2Y3A B;  4M4Z A;  1A1E A;  1K9A A;  2IUG A;  2K7A B;  1RJA A;  1BFJ A;  1FU6 A;  1LUN A;  3EAC A;  1O4F A;  3BUO B;  3IMJ A;  3N7Y A;  3S8N A;  1FMK A;  1M61 A;  2EU0 A;  2SHP A;  1O46 A;  1OPK A;  3QWX X;  2LQN A;  1UUS A;  1A09 A;  1A1C A;  4GL9 E;  2LNW A;  2MK2 A;  4K2R A;  5AXI A;  1YVL A;  1O48 A;  3S8L A;  1O4I A;  1FYR A;  2MRJ A;  4GWF A;  2PNB A;  1GRI A;  1BLK A;  3BUW B;  2H46 E;  2ETZ A;  5J3X A;  1AD5 A;  1CSZ A;  2L4K A;  1BKM A;  3PSK A;  3OV1 A;  1BKL A;  1D1Z A;  4GPL B;  2KNO A;  5CDW A;  1SHA A;  1HCS B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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