2AE0X

Crystal structure of mlta from escherichia coli reveals a unique lytic transglycosylase fold
Total Genus 95
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
335
structure length
335
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
source organism Escherichia coli
publication title Crystal Structure of MltA from Escherichia coli Reveals a Unique Lytic Transglycosylase Fold
pubmed doi rcsb
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 95
structure length 335
sequence length 335
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2005-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF03562 MltA MltA specific insert domain
X PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2ae0X01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2ae0X02
4L48A 3X2HA 4ZM7A 3X2KA 1OA7A 4JP6A 3SUJA 3X2GA 2G6GA 2PICA 1L8FA 5H4UA 5GLYA 2AE0X 1OA9A 1BW4A 3X2MA 2PJJA 4JJOA 5GM9A 3X2PA 3SUMA 4FG4A 3X2IA 3X2LA 4JCWA 3X2OA 2PI8A 2ENGA 1WC2A 3X2JA 4ENGA 3CZBA 3M3GA 4FERA 4FG2A 3SUKA 2PNWA 4FFTA 3X2NA 4JP7A 4JS7A 5GLXA 3SULA 2BH0A 1N10A 3D30A 4AVRA 1BW3A 2HCZX 3ENGA 1HD5A 2KQAA 2G5DA 2GAEA
chains in the Genus database with same CATH superfamily
1YNJD 3IR6A 4CS0A 1GTSA 4ZM7A 1QRSA 1OA7A 2Z0YA 2ZJQS 1I50A 1CZ4A 3SUJA 4GA6A 2E2IA 2JA5A 2A68D 5FTKA 5GADW 1PPYA 2JIRA 3GTKA 4AYBA 1OA9A 1TWHA 2RE8A 2PJJA 4JJOA 2YU9A 2VPWA 2V3VA 1FDOA 2EGWA 3X2LA 3X2OA 1TMOA 5GLFA 3GTOA 4E8BA 1EUYA 2E2HA 3CZBA 2ZJPS 1EXDA 1E18A 2JIPA 5B6CA 1V6ZA 5JVHS 1YNND 1KQGA 5GAHW 4JS7A 1H5NA 2E7ZA 5GLXA 5GAGW 4WF9S 1N10A 3GTJA 1B75A 2KI8A 2Y0SA 1SMYD 4JYZA 3ENGA 2A69D 1HD5A 1VC3B 3AIIA 3W2WB 3CF5S 2G5DA 3HU2A 1AA6A 1D6KA 4L48A 3X2HA 3GTMA 5C18A 1R9TA 3X2KA 1TWFA 4KDIA 5C1BA 2EEOB 2CW0D 2G6GA 1L8FA 2PICA 1GTRA 4AZDA 2O5JD 2JIOA 4H3SA 4WCES 3FKIA 5DM6S 3QWZA 2V45A 2NVXA 1UDXA 1PQHA 3X2MA 3X2PA 3QQ7A 2JA6A 3SUMA 5DYGA 5FTNA 3KW2A 2ENGA 4QIWA 4ENGA 3GTLA 1QRUA 4H4KA 3M3GA 1QCSA 1PQEA 4DMRA 3CQZA 4CRYG 3IR5A 4GA5A 3X2NA 4WFAS 1SIWA 3QQ8A 5JVGS 4JP7A 2VPXA 5IZNA 3H0GA 1PYUB 3TM7B 3D30A 4AVRA 1VHYA 1IW7D 3PLXB 5T5ID 3TIWA 2HCZX 4P2BA 3OUGA 5DYIA 1ZJWA 5T5MD 1Y5IA 2GAEA 1G8KA 1ZYRD 2NVYA 2R93A 1NYLA 2B63A 3IR7A 4JP6A 3GTPA 5GAEW 3DMRA 3X2GA 4WFBS 1G8JA 5GLYA 1QDNA 1S3SA 2AE0X 5H4UA 1NXZA 2NYAA 1I3QA 1BW4A 2JA7A 1PYQA 4IOAS 2R92A 1CR5A 4FG4A 1ZC1A 3X2IA 1R7RA 4JCWA 2VPZA 1Z85A 1WC2A 1KQFA 4KLNA 3GTQA 5FTJA 4FERA 3PIOS 1FEUA 1R27A 2PNWA 1OGYA 1WCMA 2WB1A 5DM7S 2PMZA 1UHDA 1PT1A 1AW8B 1WLFA 1Y1VA 3HU1A 1VHKA 4L69A 3GTGA 2CX8A 1E61A 2VPYA 2YUJA 2BE5D 5EPPA 1SFOA 3ML1A 4C2MA 2VUMA 4KODA 1BW3A 4D7ZB 3DLLS 4IO9S 1E5VA 1DFUP 1PT0A 3QC8A 4KDLA 4RV0A 1Q16A 2JIQA 4CRZA 4JXXA 3X1LB 4IOCS 2HZ7A 2A6HD 4AAYA 2ZJRS 4AOKB 1E60A 3HKZA 2WAQA 1TWCA 1CZ5A 3CF2A 1O0CA 2NWAA 1EU1A 1TWAA 2A6ED 4WFNS 1H0HA 4AONB 2DMRA 5GM9A 5FTLA 5BNZA 4JXZA 2C45A 1Y4ZA 1QTQA 1DMRA 3PIPS 1Y1WA 2PI8A 1QRTA 1DMSA 2JIMA 3X2JA 2RD2A 3HU3A 2R7ZA 4NOHA 3J7ZV 4UY88 4J3CA 1FDIA 4FG2A 2IV2X 3SUKA 2NAPA 4FFTA 5FTMA 4U67S 1UHEA 4V194 2EGVA 1E32A 1O0BA 3W2VB 1EUQA 3SULA 2BH0A 1PQFA 1K83A 4KO8A 2PJHB 2KQAA 3O5AA 1TWGA 5HL7S 1YLEA
chains in the Genus database with same CATH topology
1YNJD 3IR6A 4CS0A 4ZM7A 1OA7A 1I50A 1CZ4A 3SUJA 4GA6A 2E2IA 2JA5A 2A68D 5FTKA 1PPYA 2JIRA 3GTKA 4AYBA 1OA9A 1TWHA 2PJJA 4JJOA 2YU9A 2VPWA 2V3VA 1FDOA 3X2LA 3X2OA 1TMOA 5GLFA 3GTOA 2E2HA 3CZBA 1E18A 2JIPA 5B6CA 1YNND 1KQGA 4JS7A 1H5NA 2E7ZA 5GLXA 1N10A 3GTJA 2KI8A 2Y0SA 1SMYD 3ENGA 2A69D 1HD5A 1VC3B 2G5DA 3HU2A 1AA6A 4L48A 3X2HA 3GTMA 5C18A 1R9TA 3X2KA 1TWFA 4KDIA 5C1BA 2G6GA 2PICA 2EEOB 1L8FA 2CW0D 4AZDA 2O5JD 2JIOA 3FKIA 3QWZA 2V45A 2NVXA 3X2MA 1PQHA 3X2PA 3QQ7A 2JA6A 3SUMA 5DYGA 5FTNA 2ENGA 4ENGA 4QIWA 3GTLA 3M3GA 1QCSA 1PQEA 4DMRA 3CQZA 4CRYG 3IR5A 3X2NA 4GA5A 1SIWA 3QQ8A 4JP7A 2VPXA 3H0GA 1PYUB 3TM7B 3D30A 4AVRA 1IW7D 3PLXB 5T5ID 3TIWA 2HCZX 3OUGA 5DYIA 5T5MD 1Y5IA 1G8KA 2GAEA 1ZYRD 2NVYA 2R93A 2B63A 3IR7A 4JP6A 3GTPA 3DMRA 3X2GA 5H4UA 5GLYA 1G8JA 1QDNA 2AE0X 1S3SA 2NYAA 1I3QA 1BW4A 2JA7A 1PYQA 2R92A 1CR5A 4FG4A 1ZC1A 3X2IA 1R7RA 4JCWA 2VPZA 1WC2A 1KQFA 4KLNA 3GTQA 5FTJA 4FERA 2PNWA 1R27A 1OGYA 1WCMA 2WB1A 2PMZA 1UHDA 1PT1A 1AW8B 1WLFA 1Y1VA 3HU1A 3GTGA 1E61A 2VPYA 2YUJA 2BE5D 5EPPA 1SFOA 3ML1A 1BW3A 4C2MA 4KODA 2VUMA 4D7ZB 1E5VA 1PT0A 3QC8A 4KDLA 4RV0A 1Q16A 2JIQA 4CRZA 2A6HD 4AAYA 4AOKB 1E60A 3HKZA 2WAQA 1TWCA 1CZ5A 3CF2A 1EU1A 1TWAA 2A6ED 1H0HA 4AONB 5GM9A 2DMRA 5FTLA 2C45A 1Y4ZA 1DMRA 1Y1WA 2PI8A 3X2JA 1DMSA 2JIMA 3HU3A 2R7ZA 4NOHA 4FG2A 1FDIA 2IV2X 3SUKA 4FFTA 2NAPA 5FTMA 1UHEA 1E32A 3SULA 2BH0A 1PQFA 1K83A 4KO8A 2PJHB 2KQAA 3O5AA 1TWGA 1YLEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L48 A;  3X2H A;  4ZM7 A;  3X2K A;  1OA7 A;  4JP6 A;  3SUJ A;  3X2G A;  2G6G A;  2PIC A;  1L8F A;  5H4U A;  5GLY A;  2AE0 X;  1OA9 A;  1BW4 A;  3X2M A;  2PJJ A;  4JJO A;  5GM9 A;  3X2P A;  3SUM A;  4FG4 A;  3X2I A;  3X2L A;  4JCW A;  3X2O A;  2PI8 A;  2ENG A;  1WC2 A;  3X2J A;  4ENG A;  3CZB A;  3M3G A;  4FER A;  4FG2 A;  3SUK A;  2PNW A;  4FFT A;  3X2N A;  4JP7 A;  4JS7 A;  5GLX A;  3SUL A;  2BH0 A;  1N10 A;  3D30 A;  4AVR A;  1BW3 A;  2HCZ X;  3ENG A;  1HD5 A;  2KQA A;  2G5D A;  2GAE A; 
#chains in the Genus database with same CATH topology
 1YNJ D;  3IR6 A;  4CS0 A;  1GTS A;  4ZM7 A;  1QRS A;  1OA7 A;  2Z0Y A;  2ZJQ S;  1I50 A;  1CZ4 A;  3SUJ A;  4GA6 A;  2E2I A;  2JA5 A;  2A68 D;  5FTK A;  5GAD W;  1PPY A;  2JIR A;  3GTK A;  4AYB A;  1OA9 A;  1TWH A;  2RE8 A;  2PJJ A;  4JJO A;  2YU9 A;  2VPW A;  2V3V A;  1FDO A;  2EGW A;  3X2L A;  3X2O A;  1TMO A;  5GLF A;  3GTO A;  4E8B A;  1EUY A;  2E2H A;  3CZB A;  2ZJP S;  1EXD A;  1E18 A;  2JIP A;  5B6C A;  1V6Z A;  5JVH S;  1YNN D;  1KQG A;  5GAH W;  4JS7 A;  1H5N A;  2E7Z A;  5GLX A;  5GAG W;  4WF9 S;  1N10 A;  3GTJ A;  1B75 A;  2KI8 A;  2Y0S A;  1SMY D;  4JYZ A;  3ENG A;  2A69 D;  1HD5 A;  1VC3 B;  3AII A;  3W2W B;  3CF5 S;  2G5D A;  3HU2 A;  1AA6 A;  1D6K A;  4L48 A;  3X2H A;  3GTM A;  5C18 A;  1R9T A;  3X2K A;  1TWF A;  4KDI A;  5C1B A;  2EEO B;  2CW0 D;  2G6G A;  1L8F A;  2PIC A;  1GTR A;  4AZD A;  2O5J D;  2JIO A;  4H3S A;  4WCE S;  3FKI A;  5DM6 S;  3QWZ A;  2V45 A;  2NVX A;  1UDX A;  1PQH A;  3X2M A;  3X2P A;  3QQ7 A;  2JA6 A;  3SUM A;  5DYG A;  5FTN A;  3KW2 A;  2ENG A;  4QIW A;  4ENG A;  3GTL A;  1QRU A;  4H4K A;  3M3G A;  1QCS A;  1PQE A;  4DMR A;  3CQZ A;  4CRY G;  3IR5 A;  4GA5 A;  3X2N A;  4WFA S;  1SIW A;  3QQ8 A;  5JVG S;  4JP7 A;  2VPX A;  5IZN A;  3H0G A;  1PYU B;  3TM7 B;  3D30 A;  4AVR A;  1VHY A;  1IW7 D;  3PLX B;  5T5I D;  3TIW A;  2HCZ X;  4P2B A;  3OUG A;  5DYI A;  1ZJW A;  5T5M D;  1Y5I A;  2GAE A;  1G8K A;  1ZYR D;  2NVY A;  2R93 A;  1NYL A;  2B63 A;  3IR7 A;  4JP6 A;  3GTP A;  5GAE W;  3DMR A;  3X2G A;  4WFB S;  1G8J A;  5GLY A;  1QDN A;  1S3S A;  2AE0 X;  5H4U A;  1NXZ A;  2NYA A;  1I3Q A;  1BW4 A;  2JA7 A;  1PYQ A;  4IOA S;  2R92 A;  1CR5 A;  4FG4 A;  1ZC1 A;  3X2I A;  1R7R A;  4JCW A;  2VPZ A;  1Z85 A;  1WC2 A;  1KQF A;  4KLN A;  3GTQ A;  5FTJ A;  4FER A;  3PIO S;  1FEU A;  1R27 A;  2PNW A;  1OGY A;  1WCM A;  2WB1 A;  5DM7 S;  2PMZ A;  1UHD A;  1PT1 A;  1AW8 B;  1WLF A;  1Y1V A;  3HU1 A;  1VHK A;  4L69 A;  3GTG A;  2CX8 A;  1E61 A;  2VPY A;  2YUJ A;  2BE5 D;  5EPP A;  1SFO A;  3ML1 A;  4C2M A;  2VUM A;  4KOD A;  1BW3 A;  4D7Z B;  3DLL S;  4IO9 S;  1E5V A;  1DFU P;  1PT0 A;  3QC8 A;  4KDL A;  4RV0 A;  1Q16 A;  2JIQ A;  4CRZ A;  4JXX A;  3X1L B;  4IOC S;  2HZ7 A;  2A6H D;  4AAY A;  2ZJR S;  4AOK B;  1E60 A;  3HKZ A;  2WAQ A;  1TWC A;  1CZ5 A;  3CF2 A;  1O0C A;  2NWA A;  1EU1 A;  1TWA A;  2A6E D;  4WFN S;  1H0H A;  4AON B;  2DMR A;  5GM9 A;  5FTL A;  5BNZ A;  4JXZ A;  2C45 A;  1Y4Z A;  1QTQ A;  1DMR A;  3PIP S;  1Y1W A;  2PI8 A;  1QRT A;  1DMS A;  2JIM A;  3X2J A;  2RD2 A;  3HU3 A;  2R7Z A;  4NOH A;  3J7Z V;  4UY8 8;  4J3C A;  1FDI A;  4FG2 A;  2IV2 X;  3SUK A;  2NAP A;  4FFT A;  5FTM A;  4U67 S;  1UHE A;  4V19 4;  2EGV A;  1E32 A;  1O0B A;  3W2V B;  1EUQ A;  3SUL A;  2BH0 A;  1PQF A;  1K83 A;  4KO8 A;  2PJH B;  2KQA A;  3O5A A;  1TWG A;  5HL7 S;  1YLE A; 
#chains in the Genus database with same CATH homology
 1YNJ D;  3IR6 A;  4CS0 A;  4ZM7 A;  1OA7 A;  1I50 A;  1CZ4 A;  3SUJ A;  4GA6 A;  2E2I A;  2JA5 A;  2A68 D;  5FTK A;  1PPY A;  2JIR A;  3GTK A;  4AYB A;  1OA9 A;  1TWH A;  2PJJ A;  4JJO A;  2YU9 A;  2VPW A;  2V3V A;  1FDO A;  3X2L A;  3X2O A;  1TMO A;  5GLF A;  3GTO A;  2E2H A;  3CZB A;  1E18 A;  2JIP A;  5B6C A;  1YNN D;  1KQG A;  4JS7 A;  1H5N A;  2E7Z A;  5GLX A;  1N10 A;  3GTJ A;  2KI8 A;  2Y0S A;  1SMY D;  3ENG A;  2A69 D;  1HD5 A;  1VC3 B;  2G5D A;  3HU2 A;  1AA6 A;  4L48 A;  3X2H A;  3GTM A;  5C18 A;  1R9T A;  3X2K A;  1TWF A;  4KDI A;  5C1B A;  2G6G A;  2PIC A;  2EEO B;  1L8F A;  2CW0 D;  4AZD A;  2O5J D;  2JIO A;  3FKI A;  3QWZ A;  2V45 A;  2NVX A;  3X2M A;  1PQH A;  3X2P A;  3QQ7 A;  2JA6 A;  3SUM A;  5DYG A;  5FTN A;  2ENG A;  4ENG A;  4QIW A;  3GTL A;  3M3G A;  1QCS A;  1PQE A;  4DMR A;  3CQZ A;  4CRY G;  3IR5 A;  3X2N A;  4GA5 A;  1SIW A;  3QQ8 A;  4JP7 A;  2VPX A;  3H0G A;  1PYU B;  3TM7 B;  3D30 A;  4AVR A;  1IW7 D;  3PLX B;  5T5I D;  3TIW A;  2HCZ X;  3OUG A;  5DYI A;  5T5M D;  1Y5I A;  1G8K A;  2GAE A;  1ZYR D;  2NVY A;  2R93 A;  2B63 A;  3IR7 A;  4JP6 A;  3GTP A;  3DMR A;  3X2G A;  5H4U A;  5GLY A;  1G8J A;  1QDN A;  2AE0 X;  1S3S A;  2NYA A;  1I3Q A;  1BW4 A;  2JA7 A;  1PYQ A;  2R92 A;  1CR5 A;  4FG4 A;  1ZC1 A;  3X2I A;  1R7R A;  4JCW A;  2VPZ A;  1WC2 A;  1KQF A;  4KLN A;  3GTQ A;  5FTJ A;  4FER A;  2PNW A;  1R27 A;  1OGY A;  1WCM A;  2WB1 A;  2PMZ A;  1UHD A;  1PT1 A;  1AW8 B;  1WLF A;  1Y1V A;  3HU1 A;  3GTG A;  1E61 A;  2VPY A;  2YUJ A;  2BE5 D;  5EPP A;  1SFO A;  3ML1 A;  1BW3 A;  4C2M A;  4KOD A;  2VUM A;  4D7Z B;  1E5V A;  1PT0 A;  3QC8 A;  4KDL A;  4RV0 A;  1Q16 A;  2JIQ A;  4CRZ A;  2A6H D;  4AAY A;  4AOK B;  1E60 A;  3HKZ A;  2WAQ A;  1TWC A;  1CZ5 A;  3CF2 A;  1EU1 A;  1TWA A;  2A6E D;  1H0H A;  4AON B;  5GM9 A;  2DMR A;  5FTL A;  2C45 A;  1Y4Z A;  1DMR A;  1Y1W A;  2PI8 A;  3X2J A;  1DMS A;  2JIM A;  3HU3 A;  2R7Z A;  4NOH A;  4FG2 A;  1FDI A;  2IV2 X;  3SUK A;  4FFT A;  2NAP A;  5FTM A;  1UHE A;  1E32 A;  3SUL A;  2BH0 A;  1PQF A;  1K83 A;  4KO8 A;  2PJH B;  2KQA A;  3O5A A;  1TWG A;  1YLE A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...