2AE0X

Crystal structure of mlta from escherichia coli reveals a unique lytic transglycosylase fold
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
335
structure length
335
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of MltA from Escherichia coli Reveals a Unique Lytic Transglycosylase Fold
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 95
structure length 335
sequence length 335
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2005-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF03562 MltA MltA specific insert domain
X PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2ae0X01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2ae0X02
4JS7A 5GM9A 4JP6A 3X2LA 3X2MA 4FG2A 3X2OA 1WC2A 4JCWA 3X2GA 2BH0A 3X2NA 2PICA 3X2IA 3X2PA 3SULA 3SUJA 3X2JA 4FERA 3CZBA 1HD5A 2HCZX 4FFTA 3SUMA 2PNWA 5GLYA 4AVRA 4L48A 3X2HA 2GAEA 1N10A 2PI8A 4FG4A 2G6GA 1OA9A 1OA7A 3M3GA 1BW4A 3X2KA 2KQAA 3SUKA 1L8FA 2ENGA 4ENGA 2AE0X 5H4UA 4ZM7A 3D30A 4JP7A 1BW3A 2PJJA 3ENGA 2G5DA 4JJOA 5GLXA
chains in the Genus database with same CATH superfamily
3QQ7A 4CRYG 5GM9A 3X2LA 1YNND 4D7ZB 2YU9A 2VPYA 1Y5IA 5DM6S 1DFUP 5HL7S 4KODA 1EUQA 3DLLS 1YNJD 3GTMA 1Y1WA 2CW0D 4WF9S 3X1LB 1CR5A 3CZBA 3HU3A 2HCZX 3HU2A 3SUMA 2VUMA 3GTOA 4WCES 4RV0A 2BE5D 1WLFA 4L48A 5T5MD 1KQGA 1PYUB 3AIIA 1PYQA 5B6CA 3J7ZV 1ZC1A 1N10A 2VPZA 5BNZA 1H5NA 1PQFA 2CX8A 5C1BA 4FG4A 5EPPA 4WFAS 2B63A 3TIWA 1FDIA 1OA9A 4NOHA 4U67S 3X2KA 1UHDA 2KQAA 3FKIA 3CF5S 1GTSA 1TWFA 1BW3A 1VHKA 4JP7A 1CZ5A 4JYZA 4JJOA 1R7RA 1PQEA 3IR7A 3X2OA 4JS7A 3IR5A 4ZM7A 3H0GA 1I3QA 1Z85A 2ZJPS 2ZJQS 4FG2A 3GTQA 3KW2A 3HU1A 1NXZA 4WFNS 2HZ7A 1E5VA 1TWAA 2EEOB 5FTMA 1SMYD 3X2IA 3X2PA 4H4KA 1QRTA 3SULA 4GA5A 3SUJA 1PPYA 4C2MA 1CZ4A 1HD5A 5IZNA 5GADW 4V194 1G8KA 1QDNA 3W2VB 5JVGS 3ML1A 4AVRA 1SIWA 2VPWA 1DMRA 1E60A 1E61A 4P2BA 3PIPS 1Y4ZA 2PJHB 2ZJRS 1TWHA 2Y0SA 3CF2A 2G6GA 1FEUA 4KLNA 5T5ID 4E8BA 5GAHW 5FTJA 3QWZA 3M3GA 2R7ZA 5DM7S 1BW4A 2RD2A 4IO9S 1QTQA 1OGYA 1R9TA 1TMOA 2E2HA 3QC8A 5GLFA 3DMRA 3ENGA 4CRZA 4JP6A 4KO8A 3X2MA 2JA6A 1R27A 4AONB 4AYBA 5GAEW 1PT1A 2EGVA 1S3SA 2V3VA 1Q16A 2BH0A 3X2NA 2Z0YA 2V45A 2JIMA 2A69D 1D6KA 2NAPA 4FERA 3X2JA 1K83A 5FTKA 1AW8B 2R93A 2JA5A 2NVYA 3QQ8A 2E2IA 1YLEA 4WFBS 4H3SA 2WB1A 1UDXA 1I50A 4AAYA 5FTNA 3OUGA 4CS0A 3GTKA 1ZJWA 1EXDA 1H0HA 1PT0A 3GTJA 1NYLA 4JXZA 2R92A 5FTLA 1V6ZA 5JVHS 1VHYA 1DMSA 3SUKA 2WAQA 1L8FA 2ENGA 4ENGA 2AE0X 5H4UA 3TM7B 3D30A 4AZDA 1O0CA 4QIWA 5DYIA 1AA6A 2VPXA 5GLXA 1EU1A 1G8JA 1O0BA 2A6HD 1E18A 1QRSA 4J3CA 2YUJA 3HKZA 1WC2A 3O5AA 4JCWA 3X2GA 2NYAA 4KDLA 1TWGA 2KI8A 2EGWA 2PICA 3IR6A 2NWAA 1ZYRD 2A6ED 2DMRA 5GAGW 1EUYA 4JXXA 1QCSA 4DMRA 2JIRA 2JIQA 1E32A 2JIOA 3CQZA 1GTRA 4AOKB 4FFTA 1B75A 2PNWA 5GLYA 1KQFA 5DYGA 2E7ZA 4IOAS 2PMZA 1Y1VA 3X2HA 2GAEA 4UY88 1IW7D 1UHEA 1TWCA 2PI8A 3W2WB 3PIOS 1VC3B 2O5JD 3GTGA 1PQHA 4KDIA 2C45A 1OA7A 3GTLA 2JIPA 1FDOA 3PLXB 2IV2X 1SFOA 3GTPA 2RE8A 4L69A 1WCMA 2A68D 4GA6A 2PJJA 2NVXA 4IOCS 1QRUA 2G5DA 2JA7A 5C18A
chains in the Genus database with same CATH topology
3QQ7A 4CRYG 5GM9A 3X2LA 1YNND 4D7ZB 2YU9A 2VPYA 1Y5IA 4KODA 1YNJD 3GTMA 1Y1WA 2CW0D 1CR5A 3CZBA 3HU3A 2HCZX 3SUMA 3HU2A 2VUMA 3GTOA 4RV0A 4L48A 1WLFA 2BE5D 5T5MD 1KQGA 1PYUB 1PYQA 5B6CA 1ZC1A 1N10A 2VPZA 1H5NA 1PQFA 5C1BA 4FG4A 5EPPA 2B63A 3TIWA 1FDIA 1OA9A 4NOHA 3X2KA 2KQAA 1UHDA 3FKIA 1TWFA 1BW3A 4JP7A 1CZ5A 4JJOA 1R7RA 1PQEA 3X2OA 4ZM7A 4JS7A 3IR5A 3IR7A 3H0GA 1I3QA 4FG2A 3GTQA 3HU1A 1E5VA 1TWAA 2EEOB 3X2IA 3X2PA 1SMYD 5FTMA 3SULA 3SUJA 4GA5A 1PPYA 4C2MA 1CZ4A 1HD5A 1G8KA 1QDNA 4AVRA 3ML1A 1SIWA 2VPWA 1DMRA 1E60A 1E61A 1Y4ZA 2PJHB 1TWHA 2Y0SA 3CF2A 2G6GA 4KLNA 5T5ID 5FTJA 3QWZA 3M3GA 2R7ZA 1BW4A 1OGYA 1R9TA 1TMOA 2E2HA 3QC8A 5GLFA 3ENGA 3DMRA 4CRZA 4JP6A 3X2MA 4KO8A 2JA6A 1R27A 4AONB 4AYBA 1PT1A 1S3SA 2V3VA 1Q16A 2BH0A 3X2NA 2V45A 2JIMA 2A69D 3X2JA 4FERA 2NAPA 1K83A 5FTKA 1AW8B 2R93A 2JA5A 2NVYA 3QQ8A 2E2IA 1YLEA 2WB1A 1I50A 4AAYA 5FTNA 3OUGA 4CS0A 3GTKA 1H0HA 1PT0A 3GTJA 2R92A 5FTLA 1DMSA 3SUKA 2WAQA 1L8FA 2ENGA 4ENGA 2AE0X 5H4UA 3TM7B 3D30A 4AZDA 4QIWA 5DYIA 1AA6A 2VPXA 5GLXA 1EU1A 1G8JA 2A6HD 1E18A 2YUJA 3HKZA 1WC2A 4JCWA 3X2GA 3O5AA 2NYAA 4KDLA 1TWGA 2KI8A 2PICA 3IR6A 1ZYRD 2A6ED 2DMRA 1QCSA 4DMRA 2JIRA 2JIQA 1E32A 2JIOA 3CQZA 4AOKB 4FFTA 2PNWA 5GLYA 1KQFA 5DYGA 2E7ZA 2PMZA 3X2HA 1Y1VA 2GAEA 1IW7D 1UHEA 1TWCA 2PI8A 1VC3B 2O5JD 3GTGA 1PQHA 4KDIA 2C45A 1OA7A 3GTLA 2JIPA 1FDOA 3PLXB 2IV2X 1SFOA 3GTPA 1WCMA 2A68D 4GA6A 2PJJA 2NVXA 2G5DA 2JA7A 5C18A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JS7 A;  5GM9 A;  4JP6 A;  3X2L A;  3X2M A;  4FG2 A;  3X2O A;  1WC2 A;  4JCW A;  3X2G A;  2BH0 A;  3X2N A;  2PIC A;  3X2I A;  3X2P A;  3SUL A;  3SUJ A;  3X2J A;  4FER A;  3CZB A;  1HD5 A;  2HCZ X;  4FFT A;  3SUM A;  2PNW A;  5GLY A;  4AVR A;  4L48 A;  3X2H A;  2GAE A;  1N10 A;  2PI8 A;  4FG4 A;  2G6G A;  1OA9 A;  1OA7 A;  3M3G A;  1BW4 A;  3X2K A;  2KQA A;  3SUK A;  1L8F A;  2ENG A;  4ENG A;  2AE0 X;  5H4U A;  4ZM7 A;  3D30 A;  4JP7 A;  1BW3 A;  2PJJ A;  3ENG A;  2G5D A;  4JJO A;  5GLX A; 
#chains in the Genus database with same CATH topology
 3QQ7 A;  4CRY G;  5GM9 A;  3X2L A;  1YNN D;  4D7Z B;  2YU9 A;  2VPY A;  1Y5I A;  5DM6 S;  1DFU P;  5HL7 S;  4KOD A;  1EUQ A;  3DLL S;  1YNJ D;  3GTM A;  1Y1W A;  2CW0 D;  4WF9 S;  3X1L B;  1CR5 A;  3CZB A;  3HU3 A;  2HCZ X;  3HU2 A;  3SUM A;  2VUM A;  3GTO A;  4WCE S;  4RV0 A;  2BE5 D;  1WLF A;  4L48 A;  5T5M D;  1KQG A;  1PYU B;  3AII A;  1PYQ A;  5B6C A;  3J7Z V;  1ZC1 A;  1N10 A;  2VPZ A;  5BNZ A;  1H5N A;  1PQF A;  2CX8 A;  5C1B A;  4FG4 A;  5EPP A;  4WFA S;  2B63 A;  3TIW A;  1FDI A;  1OA9 A;  4NOH A;  4U67 S;  3X2K A;  1UHD A;  2KQA A;  3FKI A;  3CF5 S;  1GTS A;  1TWF A;  1BW3 A;  1VHK A;  4JP7 A;  1CZ5 A;  4JYZ A;  4JJO A;  1R7R A;  1PQE A;  3IR7 A;  3X2O A;  4JS7 A;  3IR5 A;  4ZM7 A;  3H0G A;  1I3Q A;  1Z85 A;  2ZJP S;  2ZJQ S;  4FG2 A;  3GTQ A;  3KW2 A;  3HU1 A;  1NXZ A;  4WFN S;  2HZ7 A;  1E5V A;  1TWA A;  2EEO B;  5FTM A;  1SMY D;  3X2I A;  3X2P A;  4H4K A;  1QRT A;  3SUL A;  4GA5 A;  3SUJ A;  1PPY A;  4C2M A;  1CZ4 A;  1HD5 A;  5IZN A;  5GAD W;  4V19 4;  1G8K A;  1QDN A;  3W2V B;  5JVG S;  3ML1 A;  4AVR A;  1SIW A;  2VPW A;  1DMR A;  1E60 A;  1E61 A;  4P2B A;  3PIP S;  1Y4Z A;  2PJH B;  2ZJR S;  1TWH A;  2Y0S A;  3CF2 A;  2G6G A;  1FEU A;  4KLN A;  5T5I D;  4E8B A;  5GAH W;  5FTJ A;  3QWZ A;  3M3G A;  2R7Z A;  5DM7 S;  1BW4 A;  2RD2 A;  4IO9 S;  1QTQ A;  1OGY A;  1R9T A;  1TMO A;  2E2H A;  3QC8 A;  5GLF A;  3DMR A;  3ENG A;  4CRZ A;  4JP6 A;  4KO8 A;  3X2M A;  2JA6 A;  1R27 A;  4AON B;  4AYB A;  5GAE W;  1PT1 A;  2EGV A;  1S3S A;  2V3V A;  1Q16 A;  2BH0 A;  3X2N A;  2Z0Y A;  2V45 A;  2JIM A;  2A69 D;  1D6K A;  2NAP A;  4FER A;  3X2J A;  1K83 A;  5FTK A;  1AW8 B;  2R93 A;  2JA5 A;  2NVY A;  3QQ8 A;  2E2I A;  1YLE A;  4WFB S;  4H3S A;  2WB1 A;  1UDX A;  1I50 A;  4AAY A;  5FTN A;  3OUG A;  4CS0 A;  3GTK A;  1ZJW A;  1EXD A;  1H0H A;  1PT0 A;  3GTJ A;  1NYL A;  4JXZ A;  2R92 A;  5FTL A;  1V6Z A;  5JVH S;  1VHY A;  1DMS A;  3SUK A;  2WAQ A;  1L8F A;  2ENG A;  4ENG A;  2AE0 X;  5H4U A;  3TM7 B;  3D30 A;  4AZD A;  1O0C A;  4QIW A;  5DYI A;  1AA6 A;  2VPX A;  5GLX A;  1EU1 A;  1G8J A;  1O0B A;  2A6H D;  1E18 A;  1QRS A;  4J3C A;  2YUJ A;  3HKZ A;  1WC2 A;  3O5A A;  4JCW A;  3X2G A;  2NYA A;  4KDL A;  1TWG A;  2KI8 A;  2EGW A;  2PIC A;  3IR6 A;  2NWA A;  1ZYR D;  2A6E D;  2DMR A;  5GAG W;  1EUY A;  4JXX A;  1QCS A;  4DMR A;  2JIR A;  2JIQ A;  1E32 A;  2JIO A;  3CQZ A;  1GTR A;  4AOK B;  4FFT A;  1B75 A;  2PNW A;  5GLY A;  1KQF A;  5DYG A;  2E7Z A;  4IOA S;  2PMZ A;  1Y1V A;  3X2H A;  2GAE A;  4UY8 8;  1IW7 D;  1UHE A;  1TWC A;  2PI8 A;  3W2W B;  3PIO S;  1VC3 B;  2O5J D;  3GTG A;  1PQH A;  4KDI A;  2C45 A;  1OA7 A;  3GTL A;  2JIP A;  1FDO A;  3PLX B;  2IV2 X;  1SFO A;  3GTP A;  2RE8 A;  4L69 A;  1WCM A;  2A68 D;  4GA6 A;  2PJJ A;  2NVX A;  4IOC S;  1QRU A;  2G5D A;  2JA7 A;  5C18 A; 
#chains in the Genus database with same CATH homology
 3QQ7 A;  4CRY G;  5GM9 A;  3X2L A;  1YNN D;  4D7Z B;  2YU9 A;  2VPY A;  1Y5I A;  4KOD A;  1YNJ D;  3GTM A;  1Y1W A;  2CW0 D;  1CR5 A;  3CZB A;  3HU3 A;  2HCZ X;  3SUM A;  3HU2 A;  2VUM A;  3GTO A;  4RV0 A;  4L48 A;  1WLF A;  2BE5 D;  5T5M D;  1KQG A;  1PYU B;  1PYQ A;  5B6C A;  1ZC1 A;  1N10 A;  2VPZ A;  1H5N A;  1PQF A;  5C1B A;  4FG4 A;  5EPP A;  2B63 A;  3TIW A;  1FDI A;  1OA9 A;  4NOH A;  3X2K A;  2KQA A;  1UHD A;  3FKI A;  1TWF A;  1BW3 A;  4JP7 A;  1CZ5 A;  4JJO A;  1R7R A;  1PQE A;  3X2O A;  4ZM7 A;  4JS7 A;  3IR5 A;  3IR7 A;  3H0G A;  1I3Q A;  4FG2 A;  3GTQ A;  3HU1 A;  1E5V A;  1TWA A;  2EEO B;  3X2I A;  3X2P A;  1SMY D;  5FTM A;  3SUL A;  3SUJ A;  4GA5 A;  1PPY A;  4C2M A;  1CZ4 A;  1HD5 A;  1G8K A;  1QDN A;  4AVR A;  3ML1 A;  1SIW A;  2VPW A;  1DMR A;  1E60 A;  1E61 A;  1Y4Z A;  2PJH B;  1TWH A;  2Y0S A;  3CF2 A;  2G6G A;  4KLN A;  5T5I D;  5FTJ A;  3QWZ A;  3M3G A;  2R7Z A;  1BW4 A;  1OGY A;  1R9T A;  1TMO A;  2E2H A;  3QC8 A;  5GLF A;  3ENG A;  3DMR A;  4CRZ A;  4JP6 A;  3X2M A;  4KO8 A;  2JA6 A;  1R27 A;  4AON B;  4AYB A;  1PT1 A;  1S3S A;  2V3V A;  1Q16 A;  2BH0 A;  3X2N A;  2V45 A;  2JIM A;  2A69 D;  3X2J A;  4FER A;  2NAP A;  1K83 A;  5FTK A;  1AW8 B;  2R93 A;  2JA5 A;  2NVY A;  3QQ8 A;  2E2I A;  1YLE A;  2WB1 A;  1I50 A;  4AAY A;  5FTN A;  3OUG A;  4CS0 A;  3GTK A;  1H0H A;  1PT0 A;  3GTJ A;  2R92 A;  5FTL A;  1DMS A;  3SUK A;  2WAQ A;  1L8F A;  2ENG A;  4ENG A;  2AE0 X;  5H4U A;  3TM7 B;  3D30 A;  4AZD A;  4QIW A;  5DYI A;  1AA6 A;  2VPX A;  5GLX A;  1EU1 A;  1G8J A;  2A6H D;  1E18 A;  2YUJ A;  3HKZ A;  1WC2 A;  4JCW A;  3X2G A;  3O5A A;  2NYA A;  4KDL A;  1TWG A;  2KI8 A;  2PIC A;  3IR6 A;  1ZYR D;  2A6E D;  2DMR A;  1QCS A;  4DMR A;  2JIR A;  2JIQ A;  1E32 A;  2JIO A;  3CQZ A;  4AOK B;  4FFT A;  2PNW A;  5GLY A;  1KQF A;  5DYG A;  2E7Z A;  2PMZ A;  3X2H A;  1Y1V A;  2GAE A;  1IW7 D;  1UHE A;  1TWC A;  2PI8 A;  1VC3 B;  2O5J D;  3GTG A;  1PQH A;  4KDI A;  2C45 A;  1OA7 A;  3GTL A;  2JIP A;  1FDO A;  3PLX B;  2IV2 X;  1SFO A;  3GTP A;  1WCM A;  2A68 D;  4GA6 A;  2PJJ A;  2NVX A;  2G5D A;  2JA7 A;  5C18 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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