2GAEA

Crystal structure of mlta from e. coli
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
333
structure length
333
Chain Sequence
KPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIGPEAGHRAGWYNHYGRVWVLKTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the Lytic Transglycosylase MltA from N.gonorrhoeae and E.coli: Insights into Interdomain Movements and Substrate Binding.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 89
structure length 333
sequence length 333
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2006-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2gaeA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2gaeA02
3X2MA 1HD5A 4FERA 5H4UA 3X2LA 3X2KA 3ENGA 3M3GA 5GM9A 3X2JA 3SULA 1OA9A 4ENGA 4FG2A 3X2OA 1N10A 1OA7A 4JCWA 4L48A 2G6GA 3X2GA 2ENGA 5GLXA 4ZM7A 4JJOA 4FFTA 2PJJA 2G5DA 2AE0X 5GLYA 3D30A 1BW3A 1WC2A 4FG4A 3X2NA 3SUJA 2PI8A 3X2IA 4JP6A 3SUKA 4JS7A 4JP7A 3SUMA 3X2PA 3X2HA 2BH0A 2HCZX 2KQAA 2PNWA 1BW4A 4AVRA 1L8FA 2PICA 3CZBA 2GAEA
chains in the Genus database with same CATH superfamily
1WCMA 1FDIA 5DM6S 3HU3A 1E32A 3ENGA 3M3GA 4WCES 5EPPA 1S3SA 4NOHA 2JIMA 1ZC1A 1PYUB 1EUQA 2HZ7A 3X2OA 1OA7A 4JCWA 2WAQA 4L48A 2G6GA 4D7ZB 2ENGA 3PIPS 1QRSA 1PPYA 5B6CA 2IV2X 1ZYRD 4KDIA 5GLYA 5IZNA 1E60A 3IR5A 4GA6A 2CX8A 3GTOA 1Q16A 1WC2A 1IW7D 1YLEA 1E18A 4FG4A 3X2NA 2WB1A 1R27A 1GTRA 5T5MD 3SUKA 4JYZA 3X2PA 1Y5IA 5FTMA 3X2HA 1YNJD 1TWHA 2BH0A 2A69D 1K83A 5GAEW 3DLLS 3GTGA 2BE5D 3TIWA 4CS0A 1TWGA 1O0CA 4J3CA 2Z0YA 1UHEA 3GTPA 4IO9S 3X2LA 4FERA 1PQFA 3X2KA 1FDOA 1UHDA 4KODA 1FEUA 1QDNA 1PT1A 2CW0D 4ENGA 1Y4ZA 3GTJA 2B63A 4FG2A 1B75A 1E61A 2JIPA 4ZM7A 2YU9A 3X2GA 5JVHS 2DMRA 4KLNA 5GAGW 2EEOB 1CZ4A 1GTSA 4DMRA 1SFOA 1SMYD 2PJJA 2G5DA 2VUMA 1QRUA 4KDLA 5FTJA 1QTQA 4AOKB 1BW3A 5GLFA 3KW2A 2NAPA 5FTKA 3FKIA 2E2HA 3PIOS 1VC3B 4JXXA 3X1LB 2A6ED 2VPYA 3DMRA 4V194 4L69A 1WLFA 2A68D 3X2IA 1UDXA 4JS7A 3ML1A 5DYIA 2V45A 1QCSA 2E7ZA 2HCZX 4C2MA 5DM7S 1ZJWA 1O0BA 3GTLA 2RE8A 4AVRA 4H3SA 1DFUP 1V6ZA 1PQEA 2JA7A 2GAEA 3X2MA 3QQ7A 4CRYG 1Y1VA 3H0GA 2R92A 2NVXA 1R9TA 3W2WB 3IR6A 3SULA 3TM7B 1OA9A 3IR7A 4AONB 1VHKA 5FTNA 1PT0A 2Y0SA 4IOCS 2ZJPS 5FTLA 4QIWA 1N10A 2JA5A 2NWAA 4AAYA 1KQFA 5DYGA 1H5NA 4WF9S 4FFTA 1E5VA 3CF2A 1H0HA 2A6HD 4CRZA 2ZJRS 1G8JA 3D30A 2VPWA 3HU1A 4GA5A 3GTMA 1D6KA 2KI8A 1EUYA 2V3VA 1AW8B 2E2IA 1VHYA 3SUJA 4P2BA 4AYBA 1OGYA 5BNZA 4WFAS 1QRTA 4UY88 3CQZA 1EU1A 1DMRA 2JIOA 3GTKA 2JA6A 1BW4A 2PNWA 1AA6A 3QWZA 2VPXA 2C45A 1Z85A 1TWAA 2YUJA 1R7RA 1SIWA 2JIRA 3CZBA 3O5AA 2JIQA 5T5ID 3X2JA 1TWCA 1HD5A 5H4UA 3GTQA 3W2VB 4JXZA 2ZJQS 3QQ8A 5JVGS 2R7ZA 1EXDA 5GM9A 5C1BA 4H4KA 2VPZA 2NVYA 3OUGA 2EGWA 5GAHW 1Y1WA 3CF5S 5GLXA 1NXZA 4WFBS 2PMZA 4IOAS 4JJOA 3QC8A 2EGVA 2AE0X 4AZDA 3HKZA 4RV0A 1NYLA 1G8KA 1TMOA 4KO8A 1CZ5A 5C18A 5GADW 3J7ZV 2PJHB 1YNND 3AIIA 2PI8A 2O5JD 4JP6A 1KQGA 2NYAA 1TWFA 1PQHA 4JP7A 3SUMA 3HU2A 1PYQA 2KQAA 1I50A 2R93A 4E8BA 5HL7S 4U67S 2RD2A 3PLXB 1I3QA 1L8FA 2PICA 1CR5A 4WFNS 1DMSA
chains in the Genus database with same CATH topology
1WCMA 1FDIA 3HU3A 1E32A 3ENGA 3M3GA 5EPPA 1S3SA 4NOHA 2JIMA 1ZC1A 1PYUB 3X2OA 1OA7A 4JCWA 4L48A 2WAQA 2G6GA 4D7ZB 2ENGA 1PPYA 5B6CA 2IV2X 1ZYRD 4KDIA 5GLYA 1E60A 3IR5A 4GA6A 3GTOA 1Q16A 1WC2A 1IW7D 1YLEA 1E18A 4FG4A 3X2NA 2WB1A 1R27A 5T5MD 3SUKA 3X2PA 1Y5IA 5FTMA 3X2HA 1YNJD 2BH0A 1TWHA 2A69D 1K83A 3GTGA 2BE5D 3TIWA 4CS0A 1TWGA 1UHEA 3GTPA 3X2LA 4FERA 1PQFA 3X2KA 1FDOA 1UHDA 4KODA 1QDNA 1PT1A 2CW0D 4ENGA 1Y4ZA 3GTJA 2B63A 4FG2A 1E61A 4ZM7A 2JIPA 2YU9A 3X2GA 2DMRA 4KLNA 2EEOB 1CZ4A 4DMRA 1SFOA 1SMYD 2PJJA 2G5DA 2VUMA 4KDLA 5FTJA 4AOKB 1BW3A 5GLFA 2NAPA 5FTKA 3FKIA 2E2HA 1VC3B 2A6ED 2VPYA 3DMRA 1WLFA 3X2IA 2A68D 4JS7A 3ML1A 5DYIA 2V45A 1QCSA 2E7ZA 2HCZX 4C2MA 3GTLA 4AVRA 1PQEA 2JA7A 2GAEA 3X2MA 3QQ7A 4CRYG 1Y1VA 3H0GA 2R92A 2NVXA 1R9TA 3IR6A 3SULA 3TM7B 1OA9A 3IR7A 4AONB 5FTNA 1PT0A 2Y0SA 5FTLA 4QIWA 1N10A 2JA5A 4AAYA 1KQFA 5DYGA 1H5NA 4FFTA 1E5VA 3CF2A 1H0HA 2A6HD 4CRZA 1G8JA 3D30A 2VPWA 3HU1A 4GA5A 3GTMA 2KI8A 2V3VA 1AW8B 2E2IA 3SUJA 4AYBA 1OGYA 3CQZA 1EU1A 1DMRA 2JIOA 3GTKA 1BW4A 2JA6A 2PNWA 1AA6A 3QWZA 2VPXA 2C45A 1TWAA 3CZBA 1R7RA 1SIWA 2JIRA 2YUJA 3X2JA 2JIQA 3O5AA 5T5ID 1TWCA 1HD5A 5H4UA 3GTQA 3QQ8A 2R7ZA 5GM9A 5C1BA 2VPZA 2NVYA 3OUGA 1Y1WA 5GLXA 2PMZA 4JJOA 3QC8A 2AE0X 4AZDA 3HKZA 4RV0A 1G8KA 1TMOA 4KO8A 1CZ5A 5C18A 2PJHB 1YNND 2PI8A 2O5JD 4JP6A 1KQGA 2NYAA 1TWFA 4JP7A 3SUMA 1PQHA 3HU2A 1PYQA 2KQAA 1I50A 2R93A 3PLXB 1I3QA 1L8FA 2PICA 1CR5A 1DMSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X2M A;  1HD5 A;  4FER A;  5H4U A;  3X2L A;  3X2K A;  3ENG A;  3M3G A;  5GM9 A;  3X2J A;  3SUL A;  1OA9 A;  4ENG A;  4FG2 A;  3X2O A;  1N10 A;  1OA7 A;  4JCW A;  4L48 A;  2G6G A;  3X2G A;  2ENG A;  5GLX A;  4ZM7 A;  4JJO A;  4FFT A;  2PJJ A;  2G5D A;  2AE0 X;  5GLY A;  3D30 A;  1BW3 A;  1WC2 A;  4FG4 A;  3X2N A;  3SUJ A;  2PI8 A;  3X2I A;  4JP6 A;  3SUK A;  4JS7 A;  4JP7 A;  3SUM A;  3X2P A;  3X2H A;  2BH0 A;  2HCZ X;  2KQA A;  2PNW A;  1BW4 A;  4AVR A;  1L8F A;  2PIC A;  3CZB A;  2GAE A; 
#chains in the Genus database with same CATH topology
 1WCM A;  1FDI A;  5DM6 S;  3HU3 A;  1E32 A;  3ENG A;  3M3G A;  4WCE S;  5EPP A;  1S3S A;  4NOH A;  2JIM A;  1ZC1 A;  1PYU B;  1EUQ A;  2HZ7 A;  3X2O A;  1OA7 A;  4JCW A;  2WAQ A;  4L48 A;  2G6G A;  4D7Z B;  2ENG A;  3PIP S;  1QRS A;  1PPY A;  5B6C A;  2IV2 X;  1ZYR D;  4KDI A;  5GLY A;  5IZN A;  1E60 A;  3IR5 A;  4GA6 A;  2CX8 A;  3GTO A;  1Q16 A;  1WC2 A;  1IW7 D;  1YLE A;  1E18 A;  4FG4 A;  3X2N A;  2WB1 A;  1R27 A;  1GTR A;  5T5M D;  3SUK A;  4JYZ A;  3X2P A;  1Y5I A;  5FTM A;  3X2H A;  1YNJ D;  1TWH A;  2BH0 A;  2A69 D;  1K83 A;  5GAE W;  3DLL S;  3GTG A;  2BE5 D;  3TIW A;  4CS0 A;  1TWG A;  1O0C A;  4J3C A;  2Z0Y A;  1UHE A;  3GTP A;  4IO9 S;  3X2L A;  4FER A;  1PQF A;  3X2K A;  1FDO A;  1UHD A;  4KOD A;  1FEU A;  1QDN A;  1PT1 A;  2CW0 D;  4ENG A;  1Y4Z A;  3GTJ A;  2B63 A;  4FG2 A;  1B75 A;  1E61 A;  2JIP A;  4ZM7 A;  2YU9 A;  3X2G A;  5JVH S;  2DMR A;  4KLN A;  5GAG W;  2EEO B;  1CZ4 A;  1GTS A;  4DMR A;  1SFO A;  1SMY D;  2PJJ A;  2G5D A;  2VUM A;  1QRU A;  4KDL A;  5FTJ A;  1QTQ A;  4AOK B;  1BW3 A;  5GLF A;  3KW2 A;  2NAP A;  5FTK A;  3FKI A;  2E2H A;  3PIO S;  1VC3 B;  4JXX A;  3X1L B;  2A6E D;  2VPY A;  3DMR A;  4V19 4;  4L69 A;  1WLF A;  2A68 D;  3X2I A;  1UDX A;  4JS7 A;  3ML1 A;  5DYI A;  2V45 A;  1QCS A;  2E7Z A;  2HCZ X;  4C2M A;  5DM7 S;  1ZJW A;  1O0B A;  3GTL A;  2RE8 A;  4AVR A;  4H3S A;  1DFU P;  1V6Z A;  1PQE A;  2JA7 A;  2GAE A;  3X2M A;  3QQ7 A;  4CRY G;  1Y1V A;  3H0G A;  2R92 A;  2NVX A;  1R9T A;  3W2W B;  3IR6 A;  3SUL A;  3TM7 B;  1OA9 A;  3IR7 A;  4AON B;  1VHK A;  5FTN A;  1PT0 A;  2Y0S A;  4IOC S;  2ZJP S;  5FTL A;  4QIW A;  1N10 A;  2JA5 A;  2NWA A;  4AAY A;  1KQF A;  5DYG A;  1H5N A;  4WF9 S;  4FFT A;  1E5V A;  3CF2 A;  1H0H A;  2A6H D;  4CRZ A;  2ZJR S;  1G8J A;  3D30 A;  2VPW A;  3HU1 A;  4GA5 A;  3GTM A;  1D6K A;  2KI8 A;  1EUY A;  2V3V A;  1AW8 B;  2E2I A;  1VHY A;  3SUJ A;  4P2B A;  4AYB A;  1OGY A;  5BNZ A;  4WFA S;  1QRT A;  4UY8 8;  3CQZ A;  1EU1 A;  1DMR A;  2JIO A;  3GTK A;  2JA6 A;  1BW4 A;  2PNW A;  1AA6 A;  3QWZ A;  2VPX A;  2C45 A;  1Z85 A;  1TWA A;  2YUJ A;  1R7R A;  1SIW A;  2JIR A;  3CZB A;  3O5A A;  2JIQ A;  5T5I D;  3X2J A;  1TWC A;  1HD5 A;  5H4U A;  3GTQ A;  3W2V B;  4JXZ A;  2ZJQ S;  3QQ8 A;  5JVG S;  2R7Z A;  1EXD A;  5GM9 A;  5C1B A;  4H4K A;  2VPZ A;  2NVY A;  3OUG A;  2EGW A;  5GAH W;  1Y1W A;  3CF5 S;  5GLX A;  1NXZ A;  4WFB S;  2PMZ A;  4IOA S;  4JJO A;  3QC8 A;  2EGV A;  2AE0 X;  4AZD A;  3HKZ A;  4RV0 A;  1NYL A;  1G8K A;  1TMO A;  4KO8 A;  1CZ5 A;  5C18 A;  5GAD W;  3J7Z V;  2PJH B;  1YNN D;  3AII A;  2PI8 A;  2O5J D;  4JP6 A;  1KQG A;  2NYA A;  1TWF A;  1PQH A;  4JP7 A;  3SUM A;  3HU2 A;  1PYQ A;  2KQA A;  1I50 A;  2R93 A;  4E8B A;  5HL7 S;  4U67 S;  2RD2 A;  3PLX B;  1I3Q A;  1L8F A;  2PIC A;  1CR5 A;  4WFN S;  1DMS A; 
#chains in the Genus database with same CATH homology
 1WCM A;  1FDI A;  3HU3 A;  1E32 A;  3ENG A;  3M3G A;  5EPP A;  1S3S A;  4NOH A;  2JIM A;  1ZC1 A;  1PYU B;  3X2O A;  1OA7 A;  4JCW A;  4L48 A;  2WAQ A;  2G6G A;  4D7Z B;  2ENG A;  1PPY A;  5B6C A;  2IV2 X;  1ZYR D;  4KDI A;  5GLY A;  1E60 A;  3IR5 A;  4GA6 A;  3GTO A;  1Q16 A;  1WC2 A;  1IW7 D;  1YLE A;  1E18 A;  4FG4 A;  3X2N A;  2WB1 A;  1R27 A;  5T5M D;  3SUK A;  3X2P A;  1Y5I A;  5FTM A;  3X2H A;  1YNJ D;  2BH0 A;  1TWH A;  2A69 D;  1K83 A;  3GTG A;  2BE5 D;  3TIW A;  4CS0 A;  1TWG A;  1UHE A;  3GTP A;  3X2L A;  4FER A;  1PQF A;  3X2K A;  1FDO A;  1UHD A;  4KOD A;  1QDN A;  1PT1 A;  2CW0 D;  4ENG A;  1Y4Z A;  3GTJ A;  2B63 A;  4FG2 A;  1E61 A;  4ZM7 A;  2JIP A;  2YU9 A;  3X2G A;  2DMR A;  4KLN A;  2EEO B;  1CZ4 A;  4DMR A;  1SFO A;  1SMY D;  2PJJ A;  2G5D A;  2VUM A;  4KDL A;  5FTJ A;  4AOK B;  1BW3 A;  5GLF A;  2NAP A;  5FTK A;  3FKI A;  2E2H A;  1VC3 B;  2A6E D;  2VPY A;  3DMR A;  1WLF A;  3X2I A;  2A68 D;  4JS7 A;  3ML1 A;  5DYI A;  2V45 A;  1QCS A;  2E7Z A;  2HCZ X;  4C2M A;  3GTL A;  4AVR A;  1PQE A;  2JA7 A;  2GAE A;  3X2M A;  3QQ7 A;  4CRY G;  1Y1V A;  3H0G A;  2R92 A;  2NVX A;  1R9T A;  3IR6 A;  3SUL A;  3TM7 B;  1OA9 A;  3IR7 A;  4AON B;  5FTN A;  1PT0 A;  2Y0S A;  5FTL A;  4QIW A;  1N10 A;  2JA5 A;  4AAY A;  1KQF A;  5DYG A;  1H5N A;  4FFT A;  1E5V A;  3CF2 A;  1H0H A;  2A6H D;  4CRZ A;  1G8J A;  3D30 A;  2VPW A;  3HU1 A;  4GA5 A;  3GTM A;  2KI8 A;  2V3V A;  1AW8 B;  2E2I A;  3SUJ A;  4AYB A;  1OGY A;  3CQZ A;  1EU1 A;  1DMR A;  2JIO A;  3GTK A;  1BW4 A;  2JA6 A;  2PNW A;  1AA6 A;  3QWZ A;  2VPX A;  2C45 A;  1TWA A;  3CZB A;  1R7R A;  1SIW A;  2JIR A;  2YUJ A;  3X2J A;  2JIQ A;  3O5A A;  5T5I D;  1TWC A;  1HD5 A;  5H4U A;  3GTQ A;  3QQ8 A;  2R7Z A;  5GM9 A;  5C1B A;  2VPZ A;  2NVY A;  3OUG A;  1Y1W A;  5GLX A;  2PMZ A;  4JJO A;  3QC8 A;  2AE0 X;  4AZD A;  3HKZ A;  4RV0 A;  1G8K A;  1TMO A;  4KO8 A;  1CZ5 A;  5C18 A;  2PJH B;  1YNN D;  2PI8 A;  2O5J D;  4JP6 A;  1KQG A;  2NYA A;  1TWF A;  4JP7 A;  3SUM A;  1PQH A;  3HU2 A;  1PYQ A;  2KQA A;  1I50 A;  2R93 A;  3PLX B;  1I3Q A;  1L8F A;  2PIC A;  1CR5 A;  1DMS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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