2PI8A

Crystal structure of e. coli mlta with bound chitohexaose
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
335
structure length
331
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLIAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 72
structure length 331
sequence length 335
chains with identical sequence B, C, D
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2pi8A01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2pi8A02
1OA7A 1HD5A 2ENGA 3CZBA 4JS7A 3X2LA 3X2HA 2PNWA 2G5DA 1OA9A 3D30A 4L48A 3X2OA 2BH0A 5GM9A 1BW3A 2PI8A 3ENGA 4FG2A 4FFTA 4JP6A 5GLYA 3M3GA 5H4UA 4JCWA 3SULA 2HCZX 4ENGA 1WC2A 2AE0X 2GAEA 1N10A 4ZM7A 3X2IA 4AVRA 1BW4A 4FG4A 3X2PA 3X2MA 4FERA 3X2NA 4JJOA 4JP7A 2PICA 3X2KA 1L8FA 2G6GA 2KQAA 5GLXA 3X2GA 3SUKA 3SUJA 2PJJA 3X2JA 3SUMA
chains in the Genus database with same CATH superfamily
1QTQA 1B75A 3GTKA 2EGWA 1PQHA 4U67S 4AONB 3CZBA 2PJHB 2V45A 4CRZA 4L48A 4RV0A 5FTKA 5GM9A 4L69A 2A69D 3QQ7A 4V194 1E32A 4JP6A 1BW3A 4AOKB 4FFTA 3GTPA 4H4KA 4GA6A 1UDXA 3SULA 4ENGA 1VHKA 3HKZA 5GLFA 3DLLS 4AAYA 2R7ZA 2E2IA 3O5AA 1H5NA 1H0HA 2YU9A 3X2NA 1E18A 2NAPA 2PICA 3X2KA 4WF9S 1YNND 2G6GA 4KO8A 5DYGA 1YLEA 4JXXA 1TWHA 3H0GA 3SUJA 1K83A 4IOAS 1GTRA 3DMRA 2Z0YA 1FDOA 1R9TA 2JIMA 2ZJPS 2JA7A 5GAGW 2EGVA 1HD5A 5FTLA 1I3QA 4KDLA 3X2HA 1DMRA 1Y4ZA 2WAQA 3HU3A 1V6ZA 4KDIA 1TWCA 1E60A 5FTJA 3X2OA 2ZJRS 3PLXB 2ZJQS 1AW8B 1ZC1A 4FG2A 3QWZA 1R7RA 1Y1WA 3W2WB 5JVGS 5JVHS 5DYIA 1D6KA 3QC8A 4JCWA 1YNJD 3GTOA 2A68D 2AE0X 2KI8A 5IZNA 5GADW 1I50A 2GAEA 2RE8A 2JA5A 1SIWA 1EU1A 2Y0SA 3IR7A 4QIWA 5HL7S 2YUJA 1SMYD 3X2PA 3J7ZV 5BNZA 2A6HD 1QRUA 4AZDA 1ZYRD 2WB1A 3CF5S 1UHDA 2KQAA 1KQGA 5GAEW 1NXZA 4IO9S 3SUKA 2JA6A 1CR5A 2PJJA 3HU2A 1Q16A 1QCSA 3SUMA 2R92A 2NVXA 2JIQA 1NYLA 2NWAA 4WFNS 3GTLA 1OA7A 2ENGA 1VC3B 1TWFA 1G8JA 4JS7A 4WFBS 1EUYA 3CQZA 2V3VA 3CF2A 2C45A 1OA9A 3IR5A 5C1BA 1KQFA 1Z85A 1PYQA 3OUGA 2IV2X 3GTGA 3GTJA 1OGYA 2PI8A 3ENGA 4P2BA 5GLYA 1TWAA 1IW7D 4CRYG 2E7ZA 3ML1A 4KODA 2HZ7A 3W2VB 4ZM7A 1PYUB 5EPPA 4AVRA 3TM7B 1BW4A 1GTSA 4FG4A 2PMZA 2A6ED 1WLFA 1Y5IA 3TIWA 1E5VA 3X2MA 4D7ZB 4JJOA 3PIOS 1UHEA 1O0BA 1EUQA 5FTNA 3FKIA 5FTMA 2CW0D 4CS0A 2CX8A 1L8FA 4J3CA 5GLXA 1CZ5A 4GA5A 4IOCS 3HU1A 5GAHW 2BE5D 4H3SA 2R93A 2VPWA 3GTMA 2B63A 4JYZA 1FDIA 1TMOA 3KW2A 1QDNA 4WCES 1PT1A 1CZ4A 2VPYA 5T5MD 1PQEA 3AIIA 1E61A 3X2LA 3PIPS 1QRSA 4WFAS 1AA6A 2VPZA 1DFUP 2G5DA 2PNWA 2JIPA 3GTQA 1SFOA 1VHYA 1ZJWA 3D30A 2BH0A 2JIRA 5B6CA 1PT0A 2VPXA 3M3GA 5H4UA 3IR6A 2RD2A 2NVYA 5T5ID 2VUMA 2HCZX 1O0CA 1WC2A 1QRTA 2DMRA 1G8KA 4KLNA 4NOHA 1WCMA 4E8BA 1N10A 5C18A 3X2IA 4JXZA 1EXDA 4DMRA 1Y1VA 1PPYA 1DMSA 2EEOB 4FERA 2NYAA 4JP7A 5DM7S 1R27A 2O5JD 4AYBA 4C2MA 1PQFA 2JIOA 3QQ8A 3X1LB 4UY88 3X2GA 5DM6S 1S3SA 3X2JA 1FEUA 1TWGA 2E2HA
chains in the Genus database with same CATH topology
3GTKA 1PQHA 4AONB 3CZBA 2PJHB 2V45A 4CRZA 4L48A 4RV0A 5FTKA 5GM9A 2A69D 3QQ7A 1BW3A 4JP6A 1E32A 4AOKB 4FFTA 3GTPA 4GA6A 3SULA 4ENGA 3HKZA 5GLFA 4AAYA 2R7ZA 2E2IA 3O5AA 1H5NA 1H0HA 2YU9A 3X2NA 1E18A 2PICA 2NAPA 3X2KA 1YNND 2G6GA 4KO8A 5DYGA 1YLEA 1TWHA 3SUJA 3H0GA 1K83A 3DMRA 1FDOA 1R9TA 2JIMA 2JA7A 1HD5A 5FTLA 1I3QA 4KDLA 3X2HA 1DMRA 1Y4ZA 2WAQA 3HU3A 4KDIA 1TWCA 1E60A 5FTJA 3X2OA 3PLXB 1AW8B 4FG2A 1ZC1A 3QWZA 1R7RA 1Y1WA 5DYIA 3QC8A 4JCWA 1YNJD 3GTOA 2A68D 2AE0X 2KI8A 1I50A 2GAEA 2JA5A 1SIWA 1EU1A 2Y0SA 3IR7A 4QIWA 3X2PA 1SMYD 2YUJA 2A6HD 4AZDA 1ZYRD 2WB1A 1UHDA 2KQAA 1KQGA 3SUKA 2JA6A 1CR5A 2PJJA 3HU2A 1QCSA 3SUMA 1Q16A 2R92A 2NVXA 2JIQA 3GTLA 1OA7A 2ENGA 1VC3B 1TWFA 1G8JA 4JS7A 3CQZA 2V3VA 3CF2A 2C45A 1OA9A 3IR5A 5C1BA 1KQFA 1PYQA 3OUGA 2IV2X 3GTGA 3GTJA 1OGYA 2PI8A 3ENGA 5GLYA 1TWAA 1IW7D 4CRYG 2E7ZA 3ML1A 4KODA 4ZM7A 1PYUB 5EPPA 4AVRA 1BW4A 3TM7B 4FG4A 2PMZA 3X2MA 1WLFA 2A6ED 1Y5IA 1E5VA 3TIWA 4D7ZB 4JJOA 1UHEA 5FTNA 3FKIA 5FTMA 2CW0D 4CS0A 1L8FA 5GLXA 1CZ5A 4GA5A 3HU1A 2BE5D 2R93A 2VPWA 3GTMA 2B63A 1FDIA 1TMOA 1QDNA 1PT1A 1CZ4A 2VPYA 5T5MD 1PQEA 1E61A 3X2LA 1AA6A 2VPZA 2PNWA 2G5DA 2JIPA 3GTQA 1SFOA 3D30A 2BH0A 2JIRA 5B6CA 1PT0A 3M3GA 5H4UA 2VPXA 3IR6A 2NVYA 5T5ID 2VUMA 2HCZX 1WC2A 2DMRA 1G8KA 4KLNA 4NOHA 1WCMA 1N10A 5C18A 3X2IA 4DMRA 1Y1VA 1PPYA 1DMSA 4FERA 2EEOB 2NYAA 4JP7A 1R27A 2O5JD 4AYBA 4C2MA 1PQFA 2JIOA 3QQ8A 3X2GA 1S3SA 3X2JA 1TWGA 2E2HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OA7 A;  1HD5 A;  2ENG A;  3CZB A;  4JS7 A;  3X2L A;  3X2H A;  2PNW A;  2G5D A;  1OA9 A;  3D30 A;  4L48 A;  3X2O A;  2BH0 A;  5GM9 A;  1BW3 A;  2PI8 A;  3ENG A;  4FG2 A;  4FFT A;  4JP6 A;  5GLY A;  3M3G A;  5H4U A;  4JCW A;  3SUL A;  2HCZ X;  4ENG A;  1WC2 A;  2AE0 X;  2GAE A;  1N10 A;  4ZM7 A;  3X2I A;  4AVR A;  1BW4 A;  4FG4 A;  3X2P A;  3X2M A;  4FER A;  3X2N A;  4JJO A;  4JP7 A;  2PIC A;  3X2K A;  1L8F A;  2G6G A;  2KQA A;  5GLX A;  3X2G A;  3SUK A;  3SUJ A;  2PJJ A;  3X2J A;  3SUM A; 
#chains in the Genus database with same CATH topology
 1QTQ A;  1B75 A;  3GTK A;  2EGW A;  1PQH A;  4U67 S;  4AON B;  3CZB A;  2PJH B;  2V45 A;  4CRZ A;  4L48 A;  4RV0 A;  5FTK A;  5GM9 A;  4L69 A;  2A69 D;  3QQ7 A;  4V19 4;  1E32 A;  4JP6 A;  1BW3 A;  4AOK B;  4FFT A;  3GTP A;  4H4K A;  4GA6 A;  1UDX A;  3SUL A;  4ENG A;  1VHK A;  3HKZ A;  5GLF A;  3DLL S;  4AAY A;  2R7Z A;  2E2I A;  3O5A A;  1H5N A;  1H0H A;  2YU9 A;  3X2N A;  1E18 A;  2NAP A;  2PIC A;  3X2K A;  4WF9 S;  1YNN D;  2G6G A;  4KO8 A;  5DYG A;  1YLE A;  4JXX A;  1TWH A;  3H0G A;  3SUJ A;  1K83 A;  4IOA S;  1GTR A;  3DMR A;  2Z0Y A;  1FDO A;  1R9T A;  2JIM A;  2ZJP S;  2JA7 A;  5GAG W;  2EGV A;  1HD5 A;  5FTL A;  1I3Q A;  4KDL A;  3X2H A;  1DMR A;  1Y4Z A;  2WAQ A;  3HU3 A;  1V6Z A;  4KDI A;  1TWC A;  1E60 A;  5FTJ A;  3X2O A;  2ZJR S;  3PLX B;  2ZJQ S;  1AW8 B;  1ZC1 A;  4FG2 A;  3QWZ A;  1R7R A;  1Y1W A;  3W2W B;  5JVG S;  5JVH S;  5DYI A;  1D6K A;  3QC8 A;  4JCW A;  1YNJ D;  3GTO A;  2A68 D;  2AE0 X;  2KI8 A;  5IZN A;  5GAD W;  1I50 A;  2GAE A;  2RE8 A;  2JA5 A;  1SIW A;  1EU1 A;  2Y0S A;  3IR7 A;  4QIW A;  5HL7 S;  2YUJ A;  1SMY D;  3X2P A;  3J7Z V;  5BNZ A;  2A6H D;  1QRU A;  4AZD A;  1ZYR D;  2WB1 A;  3CF5 S;  1UHD A;  2KQA A;  1KQG A;  5GAE W;  1NXZ A;  4IO9 S;  3SUK A;  2JA6 A;  1CR5 A;  2PJJ A;  3HU2 A;  1Q16 A;  1QCS A;  3SUM A;  2R92 A;  2NVX A;  2JIQ A;  1NYL A;  2NWA A;  4WFN S;  3GTL A;  1OA7 A;  2ENG A;  1VC3 B;  1TWF A;  1G8J A;  4JS7 A;  4WFB S;  1EUY A;  3CQZ A;  2V3V A;  3CF2 A;  2C45 A;  1OA9 A;  3IR5 A;  5C1B A;  1KQF A;  1Z85 A;  1PYQ A;  3OUG A;  2IV2 X;  3GTG A;  3GTJ A;  1OGY A;  2PI8 A;  3ENG A;  4P2B A;  5GLY A;  1TWA A;  1IW7 D;  4CRY G;  2E7Z A;  3ML1 A;  4KOD A;  2HZ7 A;  3W2V B;  4ZM7 A;  1PYU B;  5EPP A;  4AVR A;  3TM7 B;  1BW4 A;  1GTS A;  4FG4 A;  2PMZ A;  2A6E D;  1WLF A;  1Y5I A;  3TIW A;  1E5V A;  3X2M A;  4D7Z B;  4JJO A;  3PIO S;  1UHE A;  1O0B A;  1EUQ A;  5FTN A;  3FKI A;  5FTM A;  2CW0 D;  4CS0 A;  2CX8 A;  1L8F A;  4J3C A;  5GLX A;  1CZ5 A;  4GA5 A;  4IOC S;  3HU1 A;  5GAH W;  2BE5 D;  4H3S A;  2R93 A;  2VPW A;  3GTM A;  2B63 A;  4JYZ A;  1FDI A;  1TMO A;  3KW2 A;  1QDN A;  4WCE S;  1PT1 A;  1CZ4 A;  2VPY A;  5T5M D;  1PQE A;  3AII A;  1E61 A;  3X2L A;  3PIP S;  1QRS A;  4WFA S;  1AA6 A;  2VPZ A;  1DFU P;  2G5D A;  2PNW A;  2JIP A;  3GTQ A;  1SFO A;  1VHY A;  1ZJW A;  3D30 A;  2BH0 A;  2JIR A;  5B6C A;  1PT0 A;  2VPX A;  3M3G A;  5H4U A;  3IR6 A;  2RD2 A;  2NVY A;  5T5I D;  2VUM A;  2HCZ X;  1O0C A;  1WC2 A;  1QRT A;  2DMR A;  1G8K A;  4KLN A;  4NOH A;  1WCM A;  4E8B A;  1N10 A;  5C18 A;  3X2I A;  4JXZ A;  1EXD A;  4DMR A;  1Y1V A;  1PPY A;  1DMS A;  2EEO B;  4FER A;  2NYA A;  4JP7 A;  5DM7 S;  1R27 A;  2O5J D;  4AYB A;  4C2M A;  1PQF A;  2JIO A;  3QQ8 A;  3X1L B;  4UY8 8;  3X2G A;  5DM6 S;  1S3S A;  3X2J A;  1FEU A;  1TWG A;  2E2H A; 
#chains in the Genus database with same CATH homology
 3GTK A;  1PQH A;  4AON B;  3CZB A;  2PJH B;  2V45 A;  4CRZ A;  4L48 A;  4RV0 A;  5FTK A;  5GM9 A;  2A69 D;  3QQ7 A;  1BW3 A;  4JP6 A;  1E32 A;  4AOK B;  4FFT A;  3GTP A;  4GA6 A;  3SUL A;  4ENG A;  3HKZ A;  5GLF A;  4AAY A;  2R7Z A;  2E2I A;  3O5A A;  1H5N A;  1H0H A;  2YU9 A;  3X2N A;  1E18 A;  2PIC A;  2NAP A;  3X2K A;  1YNN D;  2G6G A;  4KO8 A;  5DYG A;  1YLE A;  1TWH A;  3SUJ A;  3H0G A;  1K83 A;  3DMR A;  1FDO A;  1R9T A;  2JIM A;  2JA7 A;  1HD5 A;  5FTL A;  1I3Q A;  4KDL A;  3X2H A;  1DMR A;  1Y4Z A;  2WAQ A;  3HU3 A;  4KDI A;  1TWC A;  1E60 A;  5FTJ A;  3X2O A;  3PLX B;  1AW8 B;  4FG2 A;  1ZC1 A;  3QWZ A;  1R7R A;  1Y1W A;  5DYI A;  3QC8 A;  4JCW A;  1YNJ D;  3GTO A;  2A68 D;  2AE0 X;  2KI8 A;  1I50 A;  2GAE A;  2JA5 A;  1SIW A;  1EU1 A;  2Y0S A;  3IR7 A;  4QIW A;  3X2P A;  1SMY D;  2YUJ A;  2A6H D;  4AZD A;  1ZYR D;  2WB1 A;  1UHD A;  2KQA A;  1KQG A;  3SUK A;  2JA6 A;  1CR5 A;  2PJJ A;  3HU2 A;  1QCS A;  3SUM A;  1Q16 A;  2R92 A;  2NVX A;  2JIQ A;  3GTL A;  1OA7 A;  2ENG A;  1VC3 B;  1TWF A;  1G8J A;  4JS7 A;  3CQZ A;  2V3V A;  3CF2 A;  2C45 A;  1OA9 A;  3IR5 A;  5C1B A;  1KQF A;  1PYQ A;  3OUG A;  2IV2 X;  3GTG A;  3GTJ A;  1OGY A;  2PI8 A;  3ENG A;  5GLY A;  1TWA A;  1IW7 D;  4CRY G;  2E7Z A;  3ML1 A;  4KOD A;  4ZM7 A;  1PYU B;  5EPP A;  4AVR A;  1BW4 A;  3TM7 B;  4FG4 A;  2PMZ A;  3X2M A;  1WLF A;  2A6E D;  1Y5I A;  1E5V A;  3TIW A;  4D7Z B;  4JJO A;  1UHE A;  5FTN A;  3FKI A;  5FTM A;  2CW0 D;  4CS0 A;  1L8F A;  5GLX A;  1CZ5 A;  4GA5 A;  3HU1 A;  2BE5 D;  2R93 A;  2VPW A;  3GTM A;  2B63 A;  1FDI A;  1TMO A;  1QDN A;  1PT1 A;  1CZ4 A;  2VPY A;  5T5M D;  1PQE A;  1E61 A;  3X2L A;  1AA6 A;  2VPZ A;  2PNW A;  2G5D A;  2JIP A;  3GTQ A;  1SFO A;  3D30 A;  2BH0 A;  2JIR A;  5B6C A;  1PT0 A;  3M3G A;  5H4U A;  2VPX A;  3IR6 A;  2NVY A;  5T5I D;  2VUM A;  2HCZ X;  1WC2 A;  2DMR A;  1G8K A;  4KLN A;  4NOH A;  1WCM A;  1N10 A;  5C18 A;  3X2I A;  4DMR A;  1Y1V A;  1PPY A;  1DMS A;  4FER A;  2EEO B;  2NYA A;  4JP7 A;  1R27 A;  2O5J D;  4AYB A;  4C2M A;  1PQF A;  2JIO A;  3QQ8 A;  3X2G A;  1S3S A;  3X2J A;  1TWG A;  2E2H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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