2PICA

E. coli lytic transglycosylase mlta-d308a in apo-2 form
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
336
structure length
336
Chain Sequence
SSKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVIIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Escherichia coli
publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 92
structure length 336
sequence length 336
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2picA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2picA02
3X2OA 3X2PA 1L8FA 5GM9A 5GLXA 5GLYA 1OA9A 4L48A 2AE0X 3X2LA 4JS7A 2G5DA 3D30A 3SUJA 1OA7A 2HCZX 2PJJA 1BW4A 3CZBA 2PNWA 2PI8A 2KQAA 3SULA 2ENGA 4AVRA 4JJOA 3X2GA 3M3GA 3X2HA 1BW3A 2PICA 3SUMA 1WC2A 4JCWA 4JP7A 4JP6A 1HD5A 2BH0A 1N10A 4FG4A 2GAEA 5H4UA 3X2NA 3X2MA 3X2IA 3X2JA 4FG2A 4ZM7A 4FERA 3ENGA 3X2KA 4FFTA 2G6GA 4ENGA 3SUKA
chains in the Genus database with same CATH superfamily
3GTKA 5GAGW 1AA6A 3QWZA 3GTMA 2Y0SA 1L8FA 1PQFA 3IR6A 1OA9A 4L48A 2NAPA 2AE0X 1Y1WA 2R7ZA 2RD2A 1R27A 4E8BA 4KODA 2HZ7A 3D30A 5GADW 2VPYA 2ZJQS 2VPZA 1Y4ZA 1S3SA 4CS0A 2E2HA 4UY88 2KI8A 1Q16A 2E7ZA 2NYAA 3CF2A 1TMOA 1BW4A 2NVYA 1G8KA 4J3CA 1QRTA 4AVRA 5T5MD 2R92A 1PYQA 4AONB 1GTSA 2VPWA 1PQHA 1PT1A 4JP6A 3X2MA 2BH0A 4WFBS 4KLNA 2GAEA 3X2NA 4AOKB 1NYLA 5DM6S 5DM7S 4ZM7A 4WFAS 1PT0A 4P2BA 2VUMA 1EU1A 2JIRA 3W2VB 4AYBA 2EGWA 1QCSA 1TWCA 1QDNA 1I3QA 2A6ED 1H0HA 1QRSA 3KW2A 1R9TA 3DLLS 1ZC1A 3IR5A 4JXXA 1O0BA 4U67S 1TWGA 1Y1VA 4D7ZB 5GLFA 4IOCS 2PMZA 1IW7D 5DYGA 2JIPA 3TM7B 1FEUA 1WCMA 3GTOA 2PJHB 3CF5S 1PQEA 2PNWA 1PPYA 3AIIA 3QQ7A 3SULA 2JA5A 4JJOA 2ZJPS 2JIOA 3W2WB 4IO9S 5HL7S 1DFUP 4JXZA 5FTLA 3SUMA 1VC3B 5GAEW 4JP7A 2JIMA 2R93A 3X1LB 4KO8A 2NWAA 4WF9S 4KDLA 1DMSA 5DYIA 4C2MA 1KQGA 2NVXA 4FERA 1K83A 4NOHA 1CZ5A 1GTRA 5FTMA 2V3VA 3X2KA 4FFTA 4KDIA 2A68D 1O0CA 4ENGA 5B6CA 3GTGA 1E32A 2ZJRS 1EUYA 1OGYA 2DMRA 4DMRA 2JIQA 5GLXA 1Y5IA 5GLYA 5GAHW 1EXDA 2CW0D 3X2LA 5EPPA 2G5DA 3SUJA 1OA7A 3HKZA 2HCZX 1E18A 3HU1A 2O5JD 1E60A 4IOAS 2PJJA 2RE8A 2WB1A 1CR5A 1UHDA 2A6HD 4H4KA 1FDIA 1E61A 2ENGA 5FTKA 4H3SA 3H0GA 2C45A 3X2GA 2YU9A 2B63A 1D6KA 1YNND 3M3GA 1BW3A 1YLEA 2JA7A 1TWHA 2JA6A 1E5VA 1WC2A 3GTJA 5JVGS 3QC8A 1QRUA 1HD5A 5H4UA 1N10A 1SIWA 1WLFA 4FG4A 1AW8B 1SMYD 4JYZA 3O5AA 3GTQA 3ENGA 3PIOS 2YUJA 4GA6A 4AZDA 1CZ4A 1I50A 1VHYA 1FDOA 1DMRA 2V45A 3ML1A 1NXZA 4V194 4CRYG 1TWAA 3X2PA 1TWFA 3X2OA 4CRZA 5GM9A 2VPXA 1SFOA 1B75A 1ZYRD 1UDXA 3PIPS 1VHKA 2CX8A 3DMRA 4JS7A 3TIWA 3J7ZV 3FKIA 5C18A 1V6ZA 1R7RA 4WCES 3IR7A 2EGVA 5FTNA 5JVHS 5IZNA 1G8JA 3CZBA 5BNZA 2PI8A 5C1BA 2KQAA 2E2IA 3OUGA 3PLXB 1EUQA 1Z85A 1ZJWA 2A69D 4QIWA 3X2HA 2BE5D 2PICA 4RV0A 1KQFA 1H5NA 4GA5A 4JCWA 5T5ID 4L69A 4WFNS 2IV2X 3X2JA 2WAQA 4AAYA 1QTQA 3X2IA 4FG2A 3CQZA 3HU2A 1YNJD 1UHEA 3HU3A 3QQ8A 5FTJA 3GTLA 3GTPA 2Z0YA 2G6GA 2EEOB 3SUKA 1PYUB
chains in the Genus database with same CATH topology
3GTKA 1AA6A 3QWZA 3GTMA 2Y0SA 1L8FA 1PQFA 3IR6A 1OA9A 4L48A 2NAPA 2AE0X 1Y1WA 2R7ZA 1R27A 4KODA 3D30A 2VPYA 2VPZA 1Y4ZA 1S3SA 4CS0A 2E2HA 2KI8A 1Q16A 1BW4A 2E7ZA 2NYAA 1TMOA 3CF2A 2NVYA 1G8KA 4AVRA 5T5MD 2R92A 1PYQA 4AONB 2VPWA 1PQHA 4JP6A 3X2MA 1PT1A 2BH0A 4KLNA 2GAEA 3X2NA 4AOKB 4ZM7A 1PT0A 2VUMA 1EU1A 2JIRA 4AYBA 1QCSA 1TWCA 1QDNA 1I3QA 2A6ED 1H0HA 1R9TA 1ZC1A 3IR5A 1TWGA 1Y1VA 4D7ZB 5GLFA 2PMZA 1IW7D 5DYGA 2JIPA 3TM7B 1WCMA 3GTOA 2PJHB 1PQEA 2PNWA 1PPYA 3QQ7A 3SULA 2JA5A 4JJOA 2JIOA 5FTLA 3SUMA 1VC3B 4JP7A 2JIMA 2R93A 4KO8A 4KDLA 1DMSA 5DYIA 4C2MA 1KQGA 2NVXA 4FERA 1K83A 4NOHA 1CZ5A 5FTMA 2V3VA 3X2KA 4FFTA 4KDIA 2A68D 4ENGA 5B6CA 3GTGA 1E32A 1OGYA 2DMRA 4DMRA 5GLXA 5GLYA 1Y5IA 2JIQA 2CW0D 3X2LA 5EPPA 2G5DA 3SUJA 1OA7A 3HKZA 2HCZX 1E18A 3HU1A 2O5JD 1E60A 2PJJA 2WB1A 1CR5A 1UHDA 2A6HD 1FDIA 1E61A 2ENGA 5FTKA 3H0GA 2C45A 3X2GA 2YU9A 2B63A 3M3GA 1YNND 1BW3A 1YLEA 2JA7A 1TWHA 2JA6A 1E5VA 1WC2A 3GTJA 3QC8A 1HD5A 5H4UA 1N10A 4FG4A 1WLFA 1SIWA 1AW8B 1SMYD 3O5AA 3GTQA 3ENGA 2YUJA 4GA6A 4AZDA 1CZ4A 1I50A 1FDOA 1DMRA 2V45A 3ML1A 4CRYG 3X2OA 3X2PA 1TWAA 1TWFA 4CRZA 5GM9A 2VPXA 1SFOA 1ZYRD 4JS7A 3DMRA 3TIWA 3FKIA 5C18A 1R7RA 3IR7A 5FTNA 1G8JA 3CZBA 2PI8A 5C1BA 2KQAA 2E2IA 3OUGA 3PLXB 2A69D 3X2HA 4QIWA 2BE5D 2PICA 4RV0A 1KQFA 1H5NA 4GA5A 4JCWA 5T5ID 3X2JA 2IV2X 2WAQA 4AAYA 3X2IA 4FG2A 3CQZA 3HU2A 1YNJD 1UHEA 3HU3A 3QQ8A 5FTJA 3GTLA 3GTPA 2G6GA 2EEOB 3SUKA 1PYUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X2O A;  3X2P A;  1L8F A;  5GM9 A;  5GLX A;  5GLY A;  1OA9 A;  4L48 A;  2AE0 X;  3X2L A;  4JS7 A;  2G5D A;  3D30 A;  3SUJ A;  1OA7 A;  2HCZ X;  2PJJ A;  1BW4 A;  3CZB A;  2PNW A;  2PI8 A;  2KQA A;  3SUL A;  2ENG A;  4AVR A;  4JJO A;  3X2G A;  3M3G A;  3X2H A;  1BW3 A;  2PIC A;  3SUM A;  1WC2 A;  4JCW A;  4JP7 A;  4JP6 A;  1HD5 A;  2BH0 A;  1N10 A;  4FG4 A;  2GAE A;  5H4U A;  3X2N A;  3X2M A;  3X2I A;  3X2J A;  4FG2 A;  4ZM7 A;  4FER A;  3ENG A;  3X2K A;  4FFT A;  2G6G A;  4ENG A;  3SUK A; 
#chains in the Genus database with same CATH topology
 3GTK A;  5GAG W;  1AA6 A;  3QWZ A;  3GTM A;  2Y0S A;  1L8F A;  1PQF A;  3IR6 A;  1OA9 A;  4L48 A;  2NAP A;  2AE0 X;  1Y1W A;  2R7Z A;  2RD2 A;  1R27 A;  4E8B A;  4KOD A;  2HZ7 A;  3D30 A;  5GAD W;  2VPY A;  2ZJQ S;  2VPZ A;  1Y4Z A;  1S3S A;  4CS0 A;  2E2H A;  4UY8 8;  2KI8 A;  1Q16 A;  2E7Z A;  2NYA A;  3CF2 A;  1TMO A;  1BW4 A;  2NVY A;  1G8K A;  4J3C A;  1QRT A;  4AVR A;  5T5M D;  2R92 A;  1PYQ A;  4AON B;  1GTS A;  2VPW A;  1PQH A;  1PT1 A;  4JP6 A;  3X2M A;  2BH0 A;  4WFB S;  4KLN A;  2GAE A;  3X2N A;  4AOK B;  1NYL A;  5DM6 S;  5DM7 S;  4ZM7 A;  4WFA S;  1PT0 A;  4P2B A;  2VUM A;  1EU1 A;  2JIR A;  3W2V B;  4AYB A;  2EGW A;  1QCS A;  1TWC A;  1QDN A;  1I3Q A;  2A6E D;  1H0H A;  1QRS A;  3KW2 A;  1R9T A;  3DLL S;  1ZC1 A;  3IR5 A;  4JXX A;  1O0B A;  4U67 S;  1TWG A;  1Y1V A;  4D7Z B;  5GLF A;  4IOC S;  2PMZ A;  1IW7 D;  5DYG A;  2JIP A;  3TM7 B;  1FEU A;  1WCM A;  3GTO A;  2PJH B;  3CF5 S;  1PQE A;  2PNW A;  1PPY A;  3AII A;  3QQ7 A;  3SUL A;  2JA5 A;  4JJO A;  2ZJP S;  2JIO A;  3W2W B;  4IO9 S;  5HL7 S;  1DFU P;  4JXZ A;  5FTL A;  3SUM A;  1VC3 B;  5GAE W;  4JP7 A;  2JIM A;  2R93 A;  3X1L B;  4KO8 A;  2NWA A;  4WF9 S;  4KDL A;  1DMS A;  5DYI A;  4C2M A;  1KQG A;  2NVX A;  4FER A;  1K83 A;  4NOH A;  1CZ5 A;  1GTR A;  5FTM A;  2V3V A;  3X2K A;  4FFT A;  4KDI A;  2A68 D;  1O0C A;  4ENG A;  5B6C A;  3GTG A;  1E32 A;  2ZJR S;  1EUY A;  1OGY A;  2DMR A;  4DMR A;  2JIQ A;  5GLX A;  1Y5I A;  5GLY A;  5GAH W;  1EXD A;  2CW0 D;  3X2L A;  5EPP A;  2G5D A;  3SUJ A;  1OA7 A;  3HKZ A;  2HCZ X;  1E18 A;  3HU1 A;  2O5J D;  1E60 A;  4IOA S;  2PJJ A;  2RE8 A;  2WB1 A;  1CR5 A;  1UHD A;  2A6H D;  4H4K A;  1FDI A;  1E61 A;  2ENG A;  5FTK A;  4H3S A;  3H0G A;  2C45 A;  3X2G A;  2YU9 A;  2B63 A;  1D6K A;  1YNN D;  3M3G A;  1BW3 A;  1YLE A;  2JA7 A;  1TWH A;  2JA6 A;  1E5V A;  1WC2 A;  3GTJ A;  5JVG S;  3QC8 A;  1QRU A;  1HD5 A;  5H4U A;  1N10 A;  1SIW A;  1WLF A;  4FG4 A;  1AW8 B;  1SMY D;  4JYZ A;  3O5A A;  3GTQ A;  3ENG A;  3PIO S;  2YUJ A;  4GA6 A;  4AZD A;  1CZ4 A;  1I50 A;  1VHY A;  1FDO A;  1DMR A;  2V45 A;  3ML1 A;  1NXZ A;  4V19 4;  4CRY G;  1TWA A;  3X2P A;  1TWF A;  3X2O A;  4CRZ A;  5GM9 A;  2VPX A;  1SFO A;  1B75 A;  1ZYR D;  1UDX A;  3PIP S;  1VHK A;  2CX8 A;  3DMR A;  4JS7 A;  3TIW A;  3J7Z V;  3FKI A;  5C18 A;  1V6Z A;  1R7R A;  4WCE S;  3IR7 A;  2EGV A;  5FTN A;  5JVH S;  5IZN A;  1G8J A;  3CZB A;  5BNZ A;  2PI8 A;  5C1B A;  2KQA A;  2E2I A;  3OUG A;  3PLX B;  1EUQ A;  1Z85 A;  1ZJW A;  2A69 D;  4QIW A;  3X2H A;  2BE5 D;  2PIC A;  4RV0 A;  1KQF A;  1H5N A;  4GA5 A;  4JCW A;  5T5I D;  4L69 A;  4WFN S;  2IV2 X;  3X2J A;  2WAQ A;  4AAY A;  1QTQ A;  3X2I A;  4FG2 A;  3CQZ A;  3HU2 A;  1YNJ D;  1UHE A;  3HU3 A;  3QQ8 A;  5FTJ A;  3GTL A;  3GTP A;  2Z0Y A;  2G6G A;  2EEO B;  3SUK A;  1PYU B; 
#chains in the Genus database with same CATH homology
 3GTK A;  1AA6 A;  3QWZ A;  3GTM A;  2Y0S A;  1L8F A;  1PQF A;  3IR6 A;  1OA9 A;  4L48 A;  2NAP A;  2AE0 X;  1Y1W A;  2R7Z A;  1R27 A;  4KOD A;  3D30 A;  2VPY A;  2VPZ A;  1Y4Z A;  1S3S A;  4CS0 A;  2E2H A;  2KI8 A;  1Q16 A;  1BW4 A;  2E7Z A;  2NYA A;  1TMO A;  3CF2 A;  2NVY A;  1G8K A;  4AVR A;  5T5M D;  2R92 A;  1PYQ A;  4AON B;  2VPW A;  1PQH A;  4JP6 A;  3X2M A;  1PT1 A;  2BH0 A;  4KLN A;  2GAE A;  3X2N A;  4AOK B;  4ZM7 A;  1PT0 A;  2VUM A;  1EU1 A;  2JIR A;  4AYB A;  1QCS A;  1TWC A;  1QDN A;  1I3Q A;  2A6E D;  1H0H A;  1R9T A;  1ZC1 A;  3IR5 A;  1TWG A;  1Y1V A;  4D7Z B;  5GLF A;  2PMZ A;  1IW7 D;  5DYG A;  2JIP A;  3TM7 B;  1WCM A;  3GTO A;  2PJH B;  1PQE A;  2PNW A;  1PPY A;  3QQ7 A;  3SUL A;  2JA5 A;  4JJO A;  2JIO A;  5FTL A;  3SUM A;  1VC3 B;  4JP7 A;  2JIM A;  2R93 A;  4KO8 A;  4KDL A;  1DMS A;  5DYI A;  4C2M A;  1KQG A;  2NVX A;  4FER A;  1K83 A;  4NOH A;  1CZ5 A;  5FTM A;  2V3V A;  3X2K A;  4FFT A;  4KDI A;  2A68 D;  4ENG A;  5B6C A;  3GTG A;  1E32 A;  1OGY A;  2DMR A;  4DMR A;  5GLX A;  5GLY A;  1Y5I A;  2JIQ A;  2CW0 D;  3X2L A;  5EPP A;  2G5D A;  3SUJ A;  1OA7 A;  3HKZ A;  2HCZ X;  1E18 A;  3HU1 A;  2O5J D;  1E60 A;  2PJJ A;  2WB1 A;  1CR5 A;  1UHD A;  2A6H D;  1FDI A;  1E61 A;  2ENG A;  5FTK A;  3H0G A;  2C45 A;  3X2G A;  2YU9 A;  2B63 A;  3M3G A;  1YNN D;  1BW3 A;  1YLE A;  2JA7 A;  1TWH A;  2JA6 A;  1E5V A;  1WC2 A;  3GTJ A;  3QC8 A;  1HD5 A;  5H4U A;  1N10 A;  4FG4 A;  1WLF A;  1SIW A;  1AW8 B;  1SMY D;  3O5A A;  3GTQ A;  3ENG A;  2YUJ A;  4GA6 A;  4AZD A;  1CZ4 A;  1I50 A;  1FDO A;  1DMR A;  2V45 A;  3ML1 A;  4CRY G;  3X2O A;  3X2P A;  1TWA A;  1TWF A;  4CRZ A;  5GM9 A;  2VPX A;  1SFO A;  1ZYR D;  4JS7 A;  3DMR A;  3TIW A;  3FKI A;  5C18 A;  1R7R A;  3IR7 A;  5FTN A;  1G8J A;  3CZB A;  2PI8 A;  5C1B A;  2KQA A;  2E2I A;  3OUG A;  3PLX B;  2A69 D;  3X2H A;  4QIW A;  2BE5 D;  2PIC A;  4RV0 A;  1KQF A;  1H5N A;  4GA5 A;  4JCW A;  5T5I D;  3X2J A;  2IV2 X;  2WAQ A;  4AAY A;  3X2I A;  4FG2 A;  3CQZ A;  3HU2 A;  1YNJ D;  1UHE A;  3HU3 A;  3QQ8 A;  5FTJ A;  3GTL A;  3GTP A;  2G6G A;  2EEO B;  3SUK A;  1PYU B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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