2PICA

E. coli lytic transglycosylase mlta-d308a in apo-2 form
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
336
structure length
336
Chain Sequence
SSKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVIIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 92
structure length 336
sequence length 336
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2picA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2picA02
3X2HA 3X2NA 5GLYA 4FG2A 3SUJA 2ENGA 3ENGA 3SUKA 3X2JA 3X2PA 2PICA 4FG4A 4JJOA 4ENGA 2AE0X 1BW3A 2PI8A 4JCWA 3X2MA 4JP6A 1HD5A 4FERA 1L8FA 3CZBA 3M3GA 2PNWA 3X2LA 2G5DA 2GAEA 1N10A 2BH0A 4L48A 3SULA 3X2KA 4ZM7A 1WC2A 2HCZX 5GLXA 3X2IA 1BW4A 2KQAA 1OA9A 4JP7A 5GM9A 3SUMA 2PJJA 4AVRA 5H4UA 3X2GA 1OA7A 3D30A 3X2OA 4FFTA 2G6GA 4JS7A
chains in the Genus database with same CATH superfamily
2JIRA 3X2NA 2HZ7A 1G8JA 5IZNA 3SUJA 2ENGA 2NAPA 1QRUA 5B6CA 1R7RA 5GADW 5T5MD 4E8BA 2EEOB 2JA6A 4JJOA 2EGVA 1TWCA 5GLFA 1Z85A 3W2WB 1FDIA 1PYQA 2PI8A 2PJHB 3GTKA 1BW3A 1NXZA 5GAEW 4H3SA 1O0CA 3GTLA 2R93A 1WLFA 4P2BA 4AAYA 3PIOS 1E61A 1VHKA 1E32A 3GTPA 1PQEA 2ZJRS 3QC8A 4L48A 3X2OA 5FTMA 3X2KA 3QQ7A 3GTMA 2B63A 4JXZA 1EU1A 3ML1A 1IW7D 3J7ZV 4WF9S 4JP7A 5GM9A 3SUMA 2PJJA 3HU3A 5FTKA 4AVRA 4JXXA 3GTGA 1OA7A 1UHEA 3CF2A 1NYLA 5FTJA 2EGWA 1EUYA 1GTSA 1AA6A 2VPYA 1DMRA 3W2VB 3IR7A 2NWAA 4WCES 3ENGA 2V45A 1QCSA 3SUKA 3X2JA 2RD2A 4WFNS 2PICA 2RE8A 5JVGS 3AIIA 4KODA 1PPYA 2JA5A 2CX8A 2R7ZA 2NYAA 4JYZA 1DFUP 1I3QA 2Y0SA 1SIWA 1L8FA 4J3CA 1PYUB 1QRSA 1TWGA 2A69D 3HKZA 3QWZA 2PNWA 2C45A 2ZJQS 4IOCS 1QRTA 1N10A 2A68D 4DMRA 2WAQA 1H0HA 2WB1A 2HCZX 2VUMA 5GLXA 3O5AA 3X2IA 2CW0D 5C1BA 5FTNA 3CF5S 1KQGA 4AYBA 1Y4ZA 5DYIA 1UHDA 4CRYG 1YNND 2VPZA 2G6GA 2A6ED 1PT0A 4JS7A 4AOKB 2NVYA 4D7ZB 2VPXA 1R9TA 3GTJA 4H4KA 2BE5D 3QQ8A 4C2MA 1DMSA 2E2IA 1EXDA 4KDLA 1V6ZA 3PLXB 3TIWA 2R92A 4AZDA 2NVXA 1TWHA 1YNJD 5GAHW 1SFOA 4FG4A 1S3SA 2O5JD 4ENGA 1Y1WA 3DLLS 2AE0X 1I50A 5GAGW 3X2MA 4L69A 4JP6A 4NOHA 5BNZA 2ZJPS 1D6KA 3X1LB 1HD5A 3IR6A 2JIQA 3KW2A 3M3GA 5T5ID 2GAEA 4QIWA 4RV0A 2Z0YA 2JA7A 2JIOA 4CRZA 4KLNA 1G8KA 3TM7B 1PQFA 1WC2A 4ZM7A 1KQFA 1K83A 3PIPS 1BW4A 4UY88 5DM6S 1TWAA 2DMRA 2E7ZA 4GA5A 1FEUA 1ZC1A 1Q16A 5H4UA 2YU9A 1H5NA 2VPWA 5DM7S 3DMRA 3IR5A 1E18A 4FFTA 2JIMA 1TMOA 3X2HA 4IO9S 1AW8B 4AONB 4V194 1UDXA 2A6HD 3CQZA 5DYGA 5GLYA 4FG2A 1Y5IA 2IV2X 4WFBS 1VHYA 1ZJWA 1QTQA 3X2PA 2E2HA 2YUJA 1TWFA 5HL7S 2V3VA 1EUQA 5FTLA 3HU2A 1OGYA 2JIPA 3FKIA 2PMZA 4IOAS 1ZYRD 5C18A 3GTQA 4KO8A 1WCMA 1E5VA 1PQHA 4JCWA 4CS0A 4GA6A 1GTRA 4U67S 1Y1VA 3GTOA 4FERA 5EPPA 1FDOA 3CZBA 3X2LA 2G5DA 5JVHS 1QDNA 3OUGA 1R27A 2BH0A 1PT1A 3H0GA 1E60A 3SULA 4KDIA 1SMYD 1B75A 1YLEA 1VC3B 1OA9A 2KQAA 1CZ5A 3X2GA 1O0BA 3HU1A 1CZ4A 4WFAS 3D30A 1CR5A 2KI8A
chains in the Genus database with same CATH topology
3X2NA 2JIRA 1G8JA 3SUJA 2ENGA 2NAPA 5B6CA 1R7RA 5T5MD 2EEOB 2JA6A 4JJOA 1TWCA 5GLFA 1FDIA 1BW3A 2PI8A 1PYQA 2PJHB 3GTKA 3GTLA 2R93A 1WLFA 4AAYA 1E61A 1E32A 3GTPA 1PQEA 4L48A 3QC8A 3X2OA 3X2KA 5FTMA 3QQ7A 3GTMA 2B63A 1EU1A 3ML1A 1IW7D 4JP7A 5GM9A 3SUMA 2PJJA 3HU3A 4AVRA 5FTKA 3GTGA 1OA7A 1UHEA 3CF2A 5FTJA 1AA6A 2VPYA 1DMRA 3IR7A 3ENGA 3SUKA 3X2JA 1QCSA 2V45A 2PICA 4KODA 1PPYA 2JA5A 2R7ZA 2NYAA 1I3QA 2Y0SA 1SIWA 1L8FA 1PYUB 1TWGA 2A69D 3HKZA 3QWZA 2PNWA 2C45A 1N10A 2A68D 4DMRA 2WAQA 1H0HA 2WB1A 2HCZX 2VUMA 5GLXA 3X2IA 3O5AA 2CW0D 5C1BA 5FTNA 1KQGA 4AYBA 1Y4ZA 5DYIA 1UHDA 4CRYG 1YNND 2VPZA 2G6GA 1PT0A 2A6ED 4JS7A 4AOKB 2NVYA 4D7ZB 2VPXA 1R9TA 3GTJA 2BE5D 3QQ8A 4C2MA 1DMSA 2E2IA 4KDLA 3PLXB 3TIWA 2R92A 4AZDA 2NVXA 1TWHA 1YNJD 1SFOA 4FG4A 1S3SA 2O5JD 4ENGA 1Y1WA 2AE0X 1I50A 3X2MA 4JP6A 4NOHA 1HD5A 3IR6A 2JIQA 3M3GA 5T5ID 2GAEA 4QIWA 4RV0A 2JA7A 2JIOA 4CRZA 4KLNA 4ZM7A 1G8KA 1PQFA 1WC2A 3TM7B 1KQFA 1K83A 1BW4A 1TWAA 2DMRA 2E7ZA 4GA5A 1ZC1A 1Q16A 5H4UA 2YU9A 1H5NA 2VPWA 4FFTA 3DMRA 1E18A 3IR5A 2JIMA 3X2HA 1TMOA 1AW8B 4AONB 2A6HD 3CQZA 5DYGA 5GLYA 4FG2A 1Y5IA 2IV2X 3X2PA 2E2HA 2YUJA 1TWFA 2V3VA 5FTLA 3HU2A 1OGYA 2JIPA 3FKIA 2PMZA 1ZYRD 5C18A 3GTQA 4KO8A 1WCMA 1E5VA 1PQHA 4JCWA 4CS0A 4GA6A 1Y1VA 3GTOA 4FERA 5EPPA 1FDOA 3CZBA 3X2LA 2G5DA 1QDNA 3OUGA 2BH0A 1R27A 1PT1A 3SULA 1E60A 3H0GA 4KDIA 1SMYD 2KQAA 1VC3B 1OA9A 1YLEA 1CZ5A 3X2GA 3HU1A 1CZ4A 3D30A 1CR5A 2KI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X2H A;  3X2N A;  5GLY A;  4FG2 A;  3SUJ A;  2ENG A;  3ENG A;  3SUK A;  3X2J A;  3X2P A;  2PIC A;  4FG4 A;  4JJO A;  4ENG A;  2AE0 X;  1BW3 A;  2PI8 A;  4JCW A;  3X2M A;  4JP6 A;  1HD5 A;  4FER A;  1L8F A;  3CZB A;  3M3G A;  2PNW A;  3X2L A;  2G5D A;  2GAE A;  1N10 A;  2BH0 A;  4L48 A;  3SUL A;  3X2K A;  4ZM7 A;  1WC2 A;  2HCZ X;  5GLX A;  3X2I A;  1BW4 A;  2KQA A;  1OA9 A;  4JP7 A;  5GM9 A;  3SUM A;  2PJJ A;  4AVR A;  5H4U A;  3X2G A;  1OA7 A;  3D30 A;  3X2O A;  4FFT A;  2G6G A;  4JS7 A; 
#chains in the Genus database with same CATH topology
 2JIR A;  3X2N A;  2HZ7 A;  1G8J A;  5IZN A;  3SUJ A;  2ENG A;  2NAP A;  1QRU A;  5B6C A;  1R7R A;  5GAD W;  5T5M D;  4E8B A;  2EEO B;  2JA6 A;  4JJO A;  2EGV A;  1TWC A;  5GLF A;  1Z85 A;  3W2W B;  1FDI A;  1PYQ A;  2PI8 A;  2PJH B;  3GTK A;  1BW3 A;  1NXZ A;  5GAE W;  4H3S A;  1O0C A;  3GTL A;  2R93 A;  1WLF A;  4P2B A;  4AAY A;  3PIO S;  1E61 A;  1VHK A;  1E32 A;  3GTP A;  1PQE A;  2ZJR S;  3QC8 A;  4L48 A;  3X2O A;  5FTM A;  3X2K A;  3QQ7 A;  3GTM A;  2B63 A;  4JXZ A;  1EU1 A;  3ML1 A;  1IW7 D;  3J7Z V;  4WF9 S;  4JP7 A;  5GM9 A;  3SUM A;  2PJJ A;  3HU3 A;  5FTK A;  4AVR A;  4JXX A;  3GTG A;  1OA7 A;  1UHE A;  3CF2 A;  1NYL A;  5FTJ A;  2EGW A;  1EUY A;  1GTS A;  1AA6 A;  2VPY A;  1DMR A;  3W2V B;  3IR7 A;  2NWA A;  4WCE S;  3ENG A;  2V45 A;  1QCS A;  3SUK A;  3X2J A;  2RD2 A;  4WFN S;  2PIC A;  2RE8 A;  5JVG S;  3AII A;  4KOD A;  1PPY A;  2JA5 A;  2CX8 A;  2R7Z A;  2NYA A;  4JYZ A;  1DFU P;  1I3Q A;  2Y0S A;  1SIW A;  1L8F A;  4J3C A;  1PYU B;  1QRS A;  1TWG A;  2A69 D;  3HKZ A;  3QWZ A;  2PNW A;  2C45 A;  2ZJQ S;  4IOC S;  1QRT A;  1N10 A;  2A68 D;  4DMR A;  2WAQ A;  1H0H A;  2WB1 A;  2HCZ X;  2VUM A;  5GLX A;  3O5A A;  3X2I A;  2CW0 D;  5C1B A;  5FTN A;  3CF5 S;  1KQG A;  4AYB A;  1Y4Z A;  5DYI A;  1UHD A;  4CRY G;  1YNN D;  2VPZ A;  2G6G A;  2A6E D;  1PT0 A;  4JS7 A;  4AOK B;  2NVY A;  4D7Z B;  2VPX A;  1R9T A;  3GTJ A;  4H4K A;  2BE5 D;  3QQ8 A;  4C2M A;  1DMS A;  2E2I A;  1EXD A;  4KDL A;  1V6Z A;  3PLX B;  3TIW A;  2R92 A;  4AZD A;  2NVX A;  1TWH A;  1YNJ D;  5GAH W;  1SFO A;  4FG4 A;  1S3S A;  2O5J D;  4ENG A;  1Y1W A;  3DLL S;  2AE0 X;  1I50 A;  5GAG W;  3X2M A;  4L69 A;  4JP6 A;  4NOH A;  5BNZ A;  2ZJP S;  1D6K A;  3X1L B;  1HD5 A;  3IR6 A;  2JIQ A;  3KW2 A;  3M3G A;  5T5I D;  2GAE A;  4QIW A;  4RV0 A;  2Z0Y A;  2JA7 A;  2JIO A;  4CRZ A;  4KLN A;  1G8K A;  3TM7 B;  1PQF A;  1WC2 A;  4ZM7 A;  1KQF A;  1K83 A;  3PIP S;  1BW4 A;  4UY8 8;  5DM6 S;  1TWA A;  2DMR A;  2E7Z A;  4GA5 A;  1FEU A;  1ZC1 A;  1Q16 A;  5H4U A;  2YU9 A;  1H5N A;  2VPW A;  5DM7 S;  3DMR A;  3IR5 A;  1E18 A;  4FFT A;  2JIM A;  1TMO A;  3X2H A;  4IO9 S;  1AW8 B;  4AON B;  4V19 4;  1UDX A;  2A6H D;  3CQZ A;  5DYG A;  5GLY A;  4FG2 A;  1Y5I A;  2IV2 X;  4WFB S;  1VHY A;  1ZJW A;  1QTQ A;  3X2P A;  2E2H A;  2YUJ A;  1TWF A;  5HL7 S;  2V3V A;  1EUQ A;  5FTL A;  3HU2 A;  1OGY A;  2JIP A;  3FKI A;  2PMZ A;  4IOA S;  1ZYR D;  5C18 A;  3GTQ A;  4KO8 A;  1WCM A;  1E5V A;  1PQH A;  4JCW A;  4CS0 A;  4GA6 A;  1GTR A;  4U67 S;  1Y1V A;  3GTO A;  4FER A;  5EPP A;  1FDO A;  3CZB A;  3X2L A;  2G5D A;  5JVH S;  1QDN A;  3OUG A;  1R27 A;  2BH0 A;  1PT1 A;  3H0G A;  1E60 A;  3SUL A;  4KDI A;  1SMY D;  1B75 A;  1YLE A;  1VC3 B;  1OA9 A;  2KQA A;  1CZ5 A;  3X2G A;  1O0B A;  3HU1 A;  1CZ4 A;  4WFA S;  3D30 A;  1CR5 A;  2KI8 A; 
#chains in the Genus database with same CATH homology
 3X2N A;  2JIR A;  1G8J A;  3SUJ A;  2ENG A;  2NAP A;  5B6C A;  1R7R A;  5T5M D;  2EEO B;  2JA6 A;  4JJO A;  1TWC A;  5GLF A;  1FDI A;  1BW3 A;  2PI8 A;  1PYQ A;  2PJH B;  3GTK A;  3GTL A;  2R93 A;  1WLF A;  4AAY A;  1E61 A;  1E32 A;  3GTP A;  1PQE A;  4L48 A;  3QC8 A;  3X2O A;  3X2K A;  5FTM A;  3QQ7 A;  3GTM A;  2B63 A;  1EU1 A;  3ML1 A;  1IW7 D;  4JP7 A;  5GM9 A;  3SUM A;  2PJJ A;  3HU3 A;  4AVR A;  5FTK A;  3GTG A;  1OA7 A;  1UHE A;  3CF2 A;  5FTJ A;  1AA6 A;  2VPY A;  1DMR A;  3IR7 A;  3ENG A;  3SUK A;  3X2J A;  1QCS A;  2V45 A;  2PIC A;  4KOD A;  1PPY A;  2JA5 A;  2R7Z A;  2NYA A;  1I3Q A;  2Y0S A;  1SIW A;  1L8F A;  1PYU B;  1TWG A;  2A69 D;  3HKZ A;  3QWZ A;  2PNW A;  2C45 A;  1N10 A;  2A68 D;  4DMR A;  2WAQ A;  1H0H A;  2WB1 A;  2HCZ X;  2VUM A;  5GLX A;  3X2I A;  3O5A A;  2CW0 D;  5C1B A;  5FTN A;  1KQG A;  4AYB A;  1Y4Z A;  5DYI A;  1UHD A;  4CRY G;  1YNN D;  2VPZ A;  2G6G A;  1PT0 A;  2A6E D;  4JS7 A;  4AOK B;  2NVY A;  4D7Z B;  2VPX A;  1R9T A;  3GTJ A;  2BE5 D;  3QQ8 A;  4C2M A;  1DMS A;  2E2I A;  4KDL A;  3PLX B;  3TIW A;  2R92 A;  4AZD A;  2NVX A;  1TWH A;  1YNJ D;  1SFO A;  4FG4 A;  1S3S A;  2O5J D;  4ENG A;  1Y1W A;  2AE0 X;  1I50 A;  3X2M A;  4JP6 A;  4NOH A;  1HD5 A;  3IR6 A;  2JIQ A;  3M3G A;  5T5I D;  2GAE A;  4QIW A;  4RV0 A;  2JA7 A;  2JIO A;  4CRZ A;  4KLN A;  4ZM7 A;  1G8K A;  1PQF A;  1WC2 A;  3TM7 B;  1KQF A;  1K83 A;  1BW4 A;  1TWA A;  2DMR A;  2E7Z A;  4GA5 A;  1ZC1 A;  1Q16 A;  5H4U A;  2YU9 A;  1H5N A;  2VPW A;  4FFT A;  3DMR A;  1E18 A;  3IR5 A;  2JIM A;  3X2H A;  1TMO A;  1AW8 B;  4AON B;  2A6H D;  3CQZ A;  5DYG A;  5GLY A;  4FG2 A;  1Y5I A;  2IV2 X;  3X2P A;  2E2H A;  2YUJ A;  1TWF A;  2V3V A;  5FTL A;  3HU2 A;  1OGY A;  2JIP A;  3FKI A;  2PMZ A;  1ZYR D;  5C18 A;  3GTQ A;  4KO8 A;  1WCM A;  1E5V A;  1PQH A;  4JCW A;  4CS0 A;  4GA6 A;  1Y1V A;  3GTO A;  4FER A;  5EPP A;  1FDO A;  3CZB A;  3X2L A;  2G5D A;  1QDN A;  3OUG A;  2BH0 A;  1R27 A;  1PT1 A;  3SUL A;  1E60 A;  3H0G A;  4KDI A;  1SMY D;  2KQA A;  1VC3 B;  1OA9 A;  1YLE A;  1CZ5 A;  3X2G A;  3HU1 A;  1CZ4 A;  3D30 A;  1CR5 A;  2KI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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