2PICA

E. coli lytic transglycosylase mlta-d308a in apo-2 form
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
336
structure length
336
Chain Sequence
SSKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVIIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 92
structure length 336
sequence length 336
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2picA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2picA02
1N10A 4ZM7A 3D30A 2KQAA 3X2PA 3X2OA 2HCZX 4JS7A 3X2MA 4FERA 1OA9A 2ENGA 3X2IA 2G5DA 2PNWA 4FG2A 3SUKA 4ENGA 2AE0X 1OA7A 3X2GA 1WC2A 1BW4A 4JJOA 2PICA 5H4UA 4L48A 5GLXA 3X2NA 3SUMA 3X2JA 5GLYA 2PI8A 1L8FA 2PJJA 4FFTA 3CZBA 4JP7A 4FG4A 3SULA 3SUJA 4AVRA 4JP6A 3M3GA 2GAEA 5GM9A 2BH0A 4JCWA 3ENGA 1BW3A 3X2KA 3X2HA 2G6GA 1HD5A 3X2LA
chains in the Genus database with same CATH superfamily
1Y4ZA 2EGVA 5GAHW 2O5JD 1UDXA 3D30A 1EUYA 1AA6A 1D6KA 1Q16A 1Y1VA 2CW0D 4CRYG 4FERA 1FEUA 3QWZA 1TMOA 2VPXA 1PYUB 4QIWA 5C1BA 1NXZA 4GA6A 1ZJWA 1PYQA 1OA9A 2VPWA 1PQFA 1DMRA 5BNZA 3J7ZV 2YU9A 2JIRA 4CRZA 4DMRA 2RD2A 3SUKA 1Z85A 2AE0X 1B75A 4WFBS 2NVYA 1FDIA 1SMYD 3GTOA 3DMRA 5T5ID 4JJOA 3KW2A 5H4UA 5DYGA 2JA6A 5GLXA 1WCMA 2A69D 1TWHA 3IR6A 1R9TA 4JXXA 3O5AA 1CR5A 2E2IA 4AZDA 4KO8A 4AVRA 1ZC1A 3IR7A 1QRTA 4JP6A 1E61A 5FTMA 1WLFA 5GM9A 5B6CA 3W2VB 1R7RA 1K83A 4P2BA 1I50A 3TIWA 2G6GA 5JVHS 1O0CA 3X2LA 1YNJD 3HU3A 4ZM7A 5FTLA 5DYIA 3TM7B 3X2OA 1TWAA 4WFAS 3DLLS 2JIOA 1KQGA 2JA7A 4E8BA 5IZNA 3CF2A 1E5VA 3OUGA 1SFOA 2ENGA 2Y0SA 3W2WB 2WB1A 4KDIA 3ML1A 4H4KA 1IW7D 3GTMA 4ENGA 1OA7A 4WF9S 1WC2A 1BW4A 1PT1A 2A68D 2E2HA 2V3VA 3PLXB 4RV0A 3X2JA 1GTRA 5GLYA 3QC8A 1OGYA 3HU2A 3QQ7A 4FG4A 4JP7A 3SULA 2NWAA 2JIPA 3GTKA 3M3GA 2NAPA 2GAEA 2R92A 1PT0A 3ENGA 1Y1WA 4H3SA 5GADW 1NYLA 1HD5A 1VHYA 1N10A 2VPYA 2CX8A 2NVXA 5C18A 5FTJA 4J3CA 5HL7S 3GTPA 2KQAA 1H5NA 1E60A 4JS7A 1S3SA 4KLNA 3X2MA 4D7ZB 4U67S 1QRUA 2JA5A 4KDLA 1TWFA 1O0BA 2JIMA 3GTLA 1R27A 2PMZA 2R7ZA 1VC3B 1YLEA 3IR5A 3X2IA 2G5DA 2R93A 4AOKB 1PPYA 3PIPS 2ZJRS 3X2GA 1V6ZA 2A6ED 1UHDA 2V45A 3AIIA 4IOAS 2WAQA 1E32A 2A6HD 3X2NA 1CZ5A 1AW8B 3SUMA 3PIOS 4JYZA 2E7ZA 2B63A 1GTSA 2BE5D 2PJJA 3FKIA 1H0HA 2YUJA 4FFTA 4CS0A 5GAGW 4WCES 1QTQA 1QRSA 4IOCS 1EU1A 4NOHA 1E18A 4GA5A 2BH0A 2IV2X 3CQZA 3X2KA 3X2HA 4AYBA 3GTQA 4JXZA 3H0GA 5FTKA 5EPPA 3GTGA 2VPZA 4UY88 1DFUP 2EEOB 3X2PA 1I3QA 2VUMA 2HCZX 1PQHA 1QDNA 1EUQA 1Y5IA 4L69A 4IO9S 3GTJA 5GAEW 2HZ7A 1SIWA 1VHKA 5FTNA 2EGWA 1UHEA 4AONB 4FG2A 2PNWA 2DMRA 1TWGA 2RE8A 2ZJPS 1PQEA 5T5MD 1KQFA 2KI8A 2PICA 1ZYRD 2JIQA 1DMSA 2C45A 4L48A 4KODA 5GLFA 2Z0YA 3CF5S 2PI8A 1L8FA 3QQ8A 4WFNS 1EXDA 4V194 4AAYA 2PJHB 1G8KA 3CZBA 3SUJA 5DM7S 1YNND 1FDOA 3HU1A 4C2MA 5DM6S 1CZ4A 2ZJQS 3HKZA 4JCWA 1BW3A 3X1LB 2NYAA 1TWCA 1G8JA 5JVGS 1QCSA
chains in the Genus database with same CATH topology
1Y4ZA 2O5JD 3D30A 1AA6A 1Q16A 1Y1VA 2CW0D 4CRYG 4FERA 3QWZA 1TMOA 2VPXA 1PYUB 4QIWA 5C1BA 4GA6A 1PYQA 1OA9A 2VPWA 1PQFA 1DMRA 2YU9A 2JIRA 4CRZA 4DMRA 3SUKA 2AE0X 2NVYA 1FDIA 1SMYD 3GTOA 3DMRA 5T5ID 4JJOA 5H4UA 5DYGA 2JA6A 5GLXA 1WCMA 2A69D 1TWHA 3IR6A 1R9TA 3O5AA 1CR5A 2E2IA 4AZDA 4AVRA 4KO8A 1ZC1A 3IR7A 4JP6A 1E61A 5FTMA 1WLFA 5GM9A 5B6CA 1R7RA 1K83A 1I50A 3TIWA 2G6GA 3X2LA 1YNJD 3HU3A 4ZM7A 5FTLA 5DYIA 3X2OA 3TM7B 1TWAA 2JIOA 1KQGA 2JA7A 3CF2A 1E5VA 3OUGA 1SFOA 2ENGA 2Y0SA 2WB1A 4KDIA 3ML1A 1IW7D 3GTMA 4ENGA 1OA7A 1WC2A 1BW4A 1PT1A 2A68D 2E2HA 2V3VA 3PLXB 4RV0A 3X2JA 5GLYA 3QC8A 1OGYA 4JP7A 3HU2A 4FG4A 3SULA 1G8JA 3QQ7A 2JIPA 3GTKA 3M3GA 2NAPA 2GAEA 2R92A 1PT0A 3ENGA 1Y1WA 1HD5A 1N10A 2VPYA 2NVXA 5C18A 5FTJA 3GTPA 2KQAA 1H5NA 1E60A 4JS7A 1S3SA 4KLNA 3X2MA 4D7ZB 2JA5A 4KDLA 1TWFA 2JIMA 3GTLA 1R27A 2PMZA 2R7ZA 1VC3B 1YLEA 3X2IA 3IR5A 2G5DA 2R93A 4AOKB 1PPYA 3X2GA 2A6ED 1UHDA 2V45A 2WAQA 1E32A 2A6HD 3X2NA 1CZ5A 1AW8B 2E7ZA 2B63A 2PJJA 2BE5D 3FKIA 4FFTA 1H0HA 2YUJA 4CS0A 1EU1A 4NOHA 1E18A 4GA5A 2BH0A 2IV2X 3CQZA 3X2KA 3X2HA 4AYBA 3GTQA 3H0GA 5FTKA 5EPPA 3GTGA 2VPZA 2EEOB 3X2PA 1I3QA 2VUMA 2HCZX 1PQHA 1QDNA 1Y5IA 3GTJA 1SIWA 5FTNA 1UHEA 4AONB 4FG2A 2PNWA 2DMRA 1TWGA 1PQEA 5T5MD 1KQFA 2KI8A 2PICA 1ZYRD 2JIQA 1DMSA 2C45A 4L48A 4KODA 5GLFA 2PI8A 1L8FA 3QQ8A 4AAYA 3CZBA 1G8KA 2PJHB 3SUJA 1YNND 1FDOA 3HU1A 4C2MA 1CZ4A 3HKZA 4JCWA 1BW3A 2NYAA 1TWCA 3SUMA 1QCSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N10 A;  4ZM7 A;  3D30 A;  2KQA A;  3X2P A;  3X2O A;  2HCZ X;  4JS7 A;  3X2M A;  4FER A;  1OA9 A;  2ENG A;  3X2I A;  2G5D A;  2PNW A;  4FG2 A;  3SUK A;  4ENG A;  2AE0 X;  1OA7 A;  3X2G A;  1WC2 A;  1BW4 A;  4JJO A;  2PIC A;  5H4U A;  4L48 A;  5GLX A;  3X2N A;  3SUM A;  3X2J A;  5GLY A;  2PI8 A;  1L8F A;  2PJJ A;  4FFT A;  3CZB A;  4JP7 A;  4FG4 A;  3SUL A;  3SUJ A;  4AVR A;  4JP6 A;  3M3G A;  2GAE A;  5GM9 A;  2BH0 A;  4JCW A;  3ENG A;  1BW3 A;  3X2K A;  3X2H A;  2G6G A;  1HD5 A;  3X2L A; 
#chains in the Genus database with same CATH topology
 1Y4Z A;  2EGV A;  5GAH W;  2O5J D;  1UDX A;  3D30 A;  1EUY A;  1AA6 A;  1D6K A;  1Q16 A;  1Y1V A;  2CW0 D;  4CRY G;  4FER A;  1FEU A;  3QWZ A;  1TMO A;  2VPX A;  1PYU B;  4QIW A;  5C1B A;  1NXZ A;  4GA6 A;  1ZJW A;  1PYQ A;  1OA9 A;  2VPW A;  1PQF A;  1DMR A;  5BNZ A;  3J7Z V;  2YU9 A;  2JIR A;  4CRZ A;  4DMR A;  2RD2 A;  3SUK A;  1Z85 A;  2AE0 X;  1B75 A;  4WFB S;  2NVY A;  1FDI A;  1SMY D;  3GTO A;  3DMR A;  5T5I D;  4JJO A;  3KW2 A;  5H4U A;  5DYG A;  2JA6 A;  5GLX A;  1WCM A;  2A69 D;  1TWH A;  3IR6 A;  1R9T A;  4JXX A;  3O5A A;  1CR5 A;  2E2I A;  4AZD A;  4KO8 A;  4AVR A;  1ZC1 A;  3IR7 A;  1QRT A;  4JP6 A;  1E61 A;  5FTM A;  1WLF A;  5GM9 A;  5B6C A;  3W2V B;  1R7R A;  1K83 A;  4P2B A;  1I50 A;  3TIW A;  2G6G A;  5JVH S;  1O0C A;  3X2L A;  1YNJ D;  3HU3 A;  4ZM7 A;  5FTL A;  5DYI A;  3TM7 B;  3X2O A;  1TWA A;  4WFA S;  3DLL S;  2JIO A;  1KQG A;  2JA7 A;  4E8B A;  5IZN A;  3CF2 A;  1E5V A;  3OUG A;  1SFO A;  2ENG A;  2Y0S A;  3W2W B;  2WB1 A;  4KDI A;  3ML1 A;  4H4K A;  1IW7 D;  3GTM A;  4ENG A;  1OA7 A;  4WF9 S;  1WC2 A;  1BW4 A;  1PT1 A;  2A68 D;  2E2H A;  2V3V A;  3PLX B;  4RV0 A;  3X2J A;  1GTR A;  5GLY A;  3QC8 A;  1OGY A;  3HU2 A;  3QQ7 A;  4FG4 A;  4JP7 A;  3SUL A;  2NWA A;  2JIP A;  3GTK A;  3M3G A;  2NAP A;  2GAE A;  2R92 A;  1PT0 A;  3ENG A;  1Y1W A;  4H3S A;  5GAD W;  1NYL A;  1HD5 A;  1VHY A;  1N10 A;  2VPY A;  2CX8 A;  2NVX A;  5C18 A;  5FTJ A;  4J3C A;  5HL7 S;  3GTP A;  2KQA A;  1H5N A;  1E60 A;  4JS7 A;  1S3S A;  4KLN A;  3X2M A;  4D7Z B;  4U67 S;  1QRU A;  2JA5 A;  4KDL A;  1TWF A;  1O0B A;  2JIM A;  3GTL A;  1R27 A;  2PMZ A;  2R7Z A;  1VC3 B;  1YLE A;  3IR5 A;  3X2I A;  2G5D A;  2R93 A;  4AOK B;  1PPY A;  3PIP S;  2ZJR S;  3X2G A;  1V6Z A;  2A6E D;  1UHD A;  2V45 A;  3AII A;  4IOA S;  2WAQ A;  1E32 A;  2A6H D;  3X2N A;  1CZ5 A;  1AW8 B;  3SUM A;  3PIO S;  4JYZ A;  2E7Z A;  2B63 A;  1GTS A;  2BE5 D;  2PJJ A;  3FKI A;  1H0H A;  2YUJ A;  4FFT A;  4CS0 A;  5GAG W;  4WCE S;  1QTQ A;  1QRS A;  4IOC S;  1EU1 A;  4NOH A;  1E18 A;  4GA5 A;  2BH0 A;  2IV2 X;  3CQZ A;  3X2K A;  3X2H A;  4AYB A;  3GTQ A;  4JXZ A;  3H0G A;  5FTK A;  5EPP A;  3GTG A;  2VPZ A;  4UY8 8;  1DFU P;  2EEO B;  3X2P A;  1I3Q A;  2VUM A;  2HCZ X;  1PQH A;  1QDN A;  1EUQ A;  1Y5I A;  4L69 A;  4IO9 S;  3GTJ A;  5GAE W;  2HZ7 A;  1SIW A;  1VHK A;  5FTN A;  2EGW A;  1UHE A;  4AON B;  4FG2 A;  2PNW A;  2DMR A;  1TWG A;  2RE8 A;  2ZJP S;  1PQE A;  5T5M D;  1KQF A;  2KI8 A;  2PIC A;  1ZYR D;  2JIQ A;  1DMS A;  2C45 A;  4L48 A;  4KOD A;  5GLF A;  2Z0Y A;  3CF5 S;  2PI8 A;  1L8F A;  3QQ8 A;  4WFN S;  1EXD A;  4V19 4;  4AAY A;  2PJH B;  1G8K A;  3CZB A;  3SUJ A;  5DM7 S;  1YNN D;  1FDO A;  3HU1 A;  4C2M A;  5DM6 S;  1CZ4 A;  2ZJQ S;  3HKZ A;  4JCW A;  1BW3 A;  3X1L B;  2NYA A;  1TWC A;  1G8J A;  5JVG S;  1QCS A; 
#chains in the Genus database with same CATH homology
 1Y4Z A;  2O5J D;  3D30 A;  1AA6 A;  1Q16 A;  1Y1V A;  2CW0 D;  4CRY G;  4FER A;  3QWZ A;  1TMO A;  2VPX A;  1PYU B;  4QIW A;  5C1B A;  4GA6 A;  1PYQ A;  1OA9 A;  2VPW A;  1PQF A;  1DMR A;  2YU9 A;  2JIR A;  4CRZ A;  4DMR A;  3SUK A;  2AE0 X;  2NVY A;  1FDI A;  1SMY D;  3GTO A;  3DMR A;  5T5I D;  4JJO A;  5H4U A;  5DYG A;  2JA6 A;  5GLX A;  1WCM A;  2A69 D;  1TWH A;  3IR6 A;  1R9T A;  3O5A A;  1CR5 A;  2E2I A;  4AZD A;  4AVR A;  4KO8 A;  1ZC1 A;  3IR7 A;  4JP6 A;  1E61 A;  5FTM A;  1WLF A;  5GM9 A;  5B6C A;  1R7R A;  1K83 A;  1I50 A;  3TIW A;  2G6G A;  3X2L A;  1YNJ D;  3HU3 A;  4ZM7 A;  5FTL A;  5DYI A;  3X2O A;  3TM7 B;  1TWA A;  2JIO A;  1KQG A;  2JA7 A;  3CF2 A;  1E5V A;  3OUG A;  1SFO A;  2ENG A;  2Y0S A;  2WB1 A;  4KDI A;  3ML1 A;  1IW7 D;  3GTM A;  4ENG A;  1OA7 A;  1WC2 A;  1BW4 A;  1PT1 A;  2A68 D;  2E2H A;  2V3V A;  3PLX B;  4RV0 A;  3X2J A;  5GLY A;  3QC8 A;  1OGY A;  4JP7 A;  3HU2 A;  4FG4 A;  3SUL A;  1G8J A;  3QQ7 A;  2JIP A;  3GTK A;  3M3G A;  2NAP A;  2GAE A;  2R92 A;  1PT0 A;  3ENG A;  1Y1W A;  1HD5 A;  1N10 A;  2VPY A;  2NVX A;  5C18 A;  5FTJ A;  3GTP A;  2KQA A;  1H5N A;  1E60 A;  4JS7 A;  1S3S A;  4KLN A;  3X2M A;  4D7Z B;  2JA5 A;  4KDL A;  1TWF A;  2JIM A;  3GTL A;  1R27 A;  2PMZ A;  2R7Z A;  1VC3 B;  1YLE A;  3X2I A;  3IR5 A;  2G5D A;  2R93 A;  4AOK B;  1PPY A;  3X2G A;  2A6E D;  1UHD A;  2V45 A;  2WAQ A;  1E32 A;  2A6H D;  3X2N A;  1CZ5 A;  1AW8 B;  2E7Z A;  2B63 A;  2PJJ A;  2BE5 D;  3FKI A;  4FFT A;  1H0H A;  2YUJ A;  4CS0 A;  1EU1 A;  4NOH A;  1E18 A;  4GA5 A;  2BH0 A;  2IV2 X;  3CQZ A;  3X2K A;  3X2H A;  4AYB A;  3GTQ A;  3H0G A;  5FTK A;  5EPP A;  3GTG A;  2VPZ A;  2EEO B;  3X2P A;  1I3Q A;  2VUM A;  2HCZ X;  1PQH A;  1QDN A;  1Y5I A;  3GTJ A;  1SIW A;  5FTN A;  1UHE A;  4AON B;  4FG2 A;  2PNW A;  2DMR A;  1TWG A;  1PQE A;  5T5M D;  1KQF A;  2KI8 A;  2PIC A;  1ZYR D;  2JIQ A;  1DMS A;  2C45 A;  4L48 A;  4KOD A;  5GLF A;  2PI8 A;  1L8F A;  3QQ8 A;  4AAY A;  3CZB A;  1G8K A;  2PJH B;  3SUJ A;  1YNN D;  1FDO A;  3HU1 A;  4C2M A;  1CZ4 A;  3HKZ A;  4JCW A;  1BW3 A;  2NYA A;  1TWC A;  3SUM A;  1QCS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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