2PJJA

E. coli lytic transglycosylase mlta-d308a in apo-1 form
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
335
structure length
335
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 94
structure length 335
sequence length 335
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2pjjA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2pjjA02
2KQAA 4JS7A 3X2JA 1BW3A 3SUJA 4JP7A 3X2GA 4JJOA 1N10A 1WC2A 2AE0X 2G6GA 5GLYA 4JP6A 3X2NA 3CZBA 3X2KA 3X2OA 2GAEA 3D30A 4ENGA 3X2IA 4ZM7A 5H4UA 4L48A 1OA7A 1BW4A 2PI8A 3X2MA 2G5DA 4AVRA 1L8FA 4FFTA 5GM9A 3M3GA 3ENGA 5GLXA 2PICA 2PNWA 4FERA 2ENGA 4FG4A 3SUMA 4JCWA 3X2HA 2BH0A 2HCZX 4FG2A 3SUKA 3X2LA 3SULA 3X2PA 2PJJA 1HD5A 1OA9A
chains in the Genus database with same CATH superfamily
2NYAA 2A6HD 4H3SA 4V194 3GTJA 4JS7A 2JIOA 2JA6A 1E60A 1H5NA 1BW3A 4JYZA 4D7ZB 3X2GA 2B63A 1EUQA 1PT1A 4AAYA 4WFNS 4WCES 2KI8A 3QQ7A 2VUMA 4IO9S 3TM7B 3X2KA 4E8BA 3CQZA 2EGVA 1PT0A 2YU9A 1GTSA 1H0HA 2VPZA 1IW7D 3H0GA 1ZC1A 4L48A 2NVYA 1QRSA 1OA7A 1PQEA 1Y5IA 3CF2A 1QRTA 1O0BA 4J3CA 4GA6A 4FFTA 1D6KA 3QQ8A 4KDIA 3M3GA 1E5VA 2C45A 2V45A 2PICA 2NVXA 4FERA 2ENGA 1WCMA 3PIPS 2PJHB 1E32A 2JIMA 1EXDA 1TWHA 3X2PA 4GA5A 2JA7A 5FTKA 1Y1WA 5T5ID 1K83A 5DYIA 3GTOA 5FTMA 3GTGA 1FEUA 1VHKA 2E7ZA 3PIOS 1DMRA 2IV2X 5GADW 1YNND 2R7ZA 2ZJQS 1QRUA 2AE0X 3GTKA 2DMRA 3IR6A 2A68D 4JP6A 3DLLS 2VPYA 4DMRA 1TMOA 4L69A 1QDNA 3GTLA 5DM7S 2GAEA 3D30A 2Z0YA 5JVGS 1B75A 4NOHA 2ZJRS 5H4UA 1GTRA 4UY88 4AOKB 5JVHS 1QCSA 2VPXA 1ZYRD 3O5AA 5C18A 4AVRA 2RE8A 1DFUP 1L8FA 2O5JD 5FTNA 2CW0D 5GLXA 1CZ4A 3GTMA 5C1BA 5BNZA 5FTLA 4AYBA 4JXXA 3SUMA 2YUJA 4JCWA 2R92A 2NWAA 1QTQA 4C2MA 4FG2A 2WAQA 3X2LA 4H4KA 3X2MA 3X2HA 1FDIA 1AA6A 2Y0SA 3X2JA 4U67S 1WLFA 4JP7A 2V3VA 1PYQA 2HZ7A 1Z85A 1UDXA 4JJOA 5GAGW 1ZJWA 1DMSA 4IOAS 5GLYA 3TIWA 2CX8A 3KW2A 3CZBA 5GLFA 1FDOA 3DMRA 2R93A 1VHYA 4AZDA 1R9TA 4CRZA 4WFBS 1R27A 3GTQA 1PPYA 1UHDA 1AW8B 1PQHA 3X2IA 2EEOB 3OUGA 4IOCS 3HU2A 2RD2A 1BW4A 3FKIA 2NAPA 4KO8A 5IZNA 4P2BA 1YNJD 3W2VB 1O0CA 3GTPA 3ML1A 1TWCA 2JIQA 3QC8A 2A69D 2PNWA 1PQFA 3W2WB 1CR5A 3AIIA 2JIPA 2JIRA 5FTJA 1YLEA 2A6ED 2BH0A 4RV0A 1NXZA 4QIWA 4WFAS 3SUKA 2ZJPS 3IR7A 3HU3A 2PJJA 1KQFA 1CZ5A 1SMYD 1HD5A 1OA9A 3ENGA 2E2IA 1EUYA 2KQAA 2E2HA 1Q16A 3J7ZV 1TWFA 4KDLA 3HU1A 4JXZA 1UHEA 1Y4ZA 5GAHW 3SUJA 1PYUB 2BE5D 4AONB 4KODA 1N10A 1WC2A 3IR5A 5B6CA 2G6GA 5GAEW 3X2NA 1NYLA 1SIWA 3X2OA 4KLNA 1E61A 5HL7S 5DYGA 4ENGA 3X1LB 1EU1A 4ZM7A 1R7RA 2WB1A 1G8JA 1VC3B 2PI8A 1TWAA 5T5MD 2G5DA 1KQGA 1G8KA 1S3SA 5GM9A 3PLXB 1V6ZA 3QWZA 5DM6S 1I3QA 3HKZA 1SFOA 4FG4A 4CS0A 4WF9S 1OGYA 2HCZX 1TWGA 1E18A 2VPWA 5EPPA 2JA5A 3SULA 1I50A 4CRYG 2EGWA 3CF5S 1Y1VA 2PMZA
chains in the Genus database with same CATH topology
2NYAA 2A6HD 3GTJA 4JS7A 2JIOA 2JA6A 1E60A 1H5NA 1BW3A 4D7ZB 3X2GA 2B63A 1PT1A 4AAYA 2KI8A 3QQ7A 2VUMA 3X2KA 3TM7B 3CQZA 1PT0A 2YU9A 1H0HA 2VPZA 1IW7D 3H0GA 1ZC1A 4L48A 2NVYA 1OA7A 1PQEA 1Y5IA 3CF2A 4GA6A 4FFTA 3QQ8A 4KDIA 3M3GA 1E5VA 2C45A 2V45A 2PICA 2NVXA 4FERA 2ENGA 1WCMA 2PJHB 1E32A 2JIMA 1TWHA 3X2PA 4GA5A 2JA7A 5FTKA 1Y1WA 5T5ID 1K83A 5DYIA 3GTOA 5FTMA 3GTGA 2E7ZA 1DMRA 2IV2X 1YNND 2R7ZA 2AE0X 3GTKA 2DMRA 3IR6A 2A68D 4JP6A 2VPYA 4DMRA 1TMOA 1QDNA 3GTLA 2GAEA 3D30A 4NOHA 5H4UA 4AOKB 1QCSA 2VPXA 1ZYRD 3O5AA 5C18A 4AVRA 1L8FA 2O5JD 5FTNA 5GLXA 2CW0D 1CZ4A 3GTMA 5C1BA 5FTLA 4AYBA 3SUMA 2YUJA 4JCWA 2R92A 4C2MA 4FG2A 2WAQA 3X2LA 3X2MA 3X2HA 1FDIA 1AA6A 2Y0SA 3X2JA 1WLFA 4JP7A 2V3VA 1PYQA 4JJOA 1DMSA 5GLYA 3TIWA 3CZBA 5GLFA 1FDOA 3DMRA 2R93A 4AZDA 1R9TA 4CRZA 1R27A 3GTQA 3X2IA 1PPYA 1AW8B 1PQHA 1UHDA 2EEOB 3OUGA 3HU2A 1BW4A 3FKIA 2NAPA 4KO8A 1YNJD 3GTPA 3ML1A 1TWCA 2JIQA 3QC8A 2A69D 2PNWA 1PQFA 1CR5A 2JIPA 2JIRA 5FTJA 1YLEA 2A6ED 2BH0A 4RV0A 4QIWA 3SUKA 3IR7A 3HU3A 2PJJA 1KQFA 1CZ5A 1SMYD 1HD5A 3ENGA 1OA9A 2E2IA 2KQAA 2E2HA 1Q16A 1TWFA 4KDLA 3HU1A 1UHEA 1Y4ZA 3SUJA 1PYUB 2BE5D 4AONB 4KODA 1N10A 1WC2A 3IR5A 5B6CA 2G6GA 3X2NA 1SIWA 3X2OA 4KLNA 1E61A 5DYGA 4ENGA 1EU1A 4ZM7A 1R7RA 2WB1A 1G8JA 1VC3B 2PI8A 1TWAA 5T5MD 2G5DA 1KQGA 1G8KA 1S3SA 5GM9A 3PLXB 3QWZA 1I3QA 3HKZA 1SFOA 4FG4A 4CS0A 1OGYA 2HCZX 1TWGA 1E18A 2VPWA 5EPPA 2JA5A 3SULA 1I50A 4CRYG 1Y1VA 2PMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KQA A;  4JS7 A;  3X2J A;  1BW3 A;  3SUJ A;  4JP7 A;  3X2G A;  4JJO A;  1N10 A;  1WC2 A;  2AE0 X;  2G6G A;  5GLY A;  4JP6 A;  3X2N A;  3CZB A;  3X2K A;  3X2O A;  2GAE A;  3D30 A;  4ENG A;  3X2I A;  4ZM7 A;  5H4U A;  4L48 A;  1OA7 A;  1BW4 A;  2PI8 A;  3X2M A;  2G5D A;  4AVR A;  1L8F A;  4FFT A;  5GM9 A;  3M3G A;  3ENG A;  5GLX A;  2PIC A;  2PNW A;  4FER A;  2ENG A;  4FG4 A;  3SUM A;  4JCW A;  3X2H A;  2BH0 A;  2HCZ X;  4FG2 A;  3SUK A;  3X2L A;  3SUL A;  3X2P A;  2PJJ A;  1HD5 A;  1OA9 A; 
#chains in the Genus database with same CATH topology
 2NYA A;  2A6H D;  4H3S A;  4V19 4;  3GTJ A;  4JS7 A;  2JIO A;  2JA6 A;  1E60 A;  1H5N A;  1BW3 A;  4JYZ A;  4D7Z B;  3X2G A;  2B63 A;  1EUQ A;  1PT1 A;  4AAY A;  4WFN S;  4WCE S;  2KI8 A;  3QQ7 A;  2VUM A;  4IO9 S;  3TM7 B;  3X2K A;  4E8B A;  3CQZ A;  2EGV A;  1PT0 A;  2YU9 A;  1GTS A;  1H0H A;  2VPZ A;  1IW7 D;  3H0G A;  1ZC1 A;  4L48 A;  2NVY A;  1QRS A;  1OA7 A;  1PQE A;  1Y5I A;  3CF2 A;  1QRT A;  1O0B A;  4J3C A;  4GA6 A;  4FFT A;  1D6K A;  3QQ8 A;  4KDI A;  3M3G A;  1E5V A;  2C45 A;  2V45 A;  2PIC A;  2NVX A;  4FER A;  2ENG A;  1WCM A;  3PIP S;  2PJH B;  1E32 A;  2JIM A;  1EXD A;  1TWH A;  3X2P A;  4GA5 A;  2JA7 A;  5FTK A;  1Y1W A;  5T5I D;  1K83 A;  5DYI A;  3GTO A;  5FTM A;  3GTG A;  1FEU A;  1VHK A;  2E7Z A;  3PIO S;  1DMR A;  2IV2 X;  5GAD W;  1YNN D;  2R7Z A;  2ZJQ S;  1QRU A;  2AE0 X;  3GTK A;  2DMR A;  3IR6 A;  2A68 D;  4JP6 A;  3DLL S;  2VPY A;  4DMR A;  1TMO A;  4L69 A;  1QDN A;  3GTL A;  5DM7 S;  2GAE A;  3D30 A;  2Z0Y A;  5JVG S;  1B75 A;  4NOH A;  2ZJR S;  5H4U A;  1GTR A;  4UY8 8;  4AOK B;  5JVH S;  1QCS A;  2VPX A;  1ZYR D;  3O5A A;  5C18 A;  4AVR A;  2RE8 A;  1DFU P;  1L8F A;  2O5J D;  5FTN A;  2CW0 D;  5GLX A;  1CZ4 A;  3GTM A;  5C1B A;  5BNZ A;  5FTL A;  4AYB A;  4JXX A;  3SUM A;  2YUJ A;  4JCW A;  2R92 A;  2NWA A;  1QTQ A;  4C2M A;  4FG2 A;  2WAQ A;  3X2L A;  4H4K A;  3X2M A;  3X2H A;  1FDI A;  1AA6 A;  2Y0S A;  3X2J A;  4U67 S;  1WLF A;  4JP7 A;  2V3V A;  1PYQ A;  2HZ7 A;  1Z85 A;  1UDX A;  4JJO A;  5GAG W;  1ZJW A;  1DMS A;  4IOA S;  5GLY A;  3TIW A;  2CX8 A;  3KW2 A;  3CZB A;  5GLF A;  1FDO A;  3DMR A;  2R93 A;  1VHY A;  4AZD A;  1R9T A;  4CRZ A;  4WFB S;  1R27 A;  3GTQ A;  1PPY A;  1UHD A;  1AW8 B;  1PQH A;  3X2I A;  2EEO B;  3OUG A;  4IOC S;  3HU2 A;  2RD2 A;  1BW4 A;  3FKI A;  2NAP A;  4KO8 A;  5IZN A;  4P2B A;  1YNJ D;  3W2V B;  1O0C A;  3GTP A;  3ML1 A;  1TWC A;  2JIQ A;  3QC8 A;  2A69 D;  2PNW A;  1PQF A;  3W2W B;  1CR5 A;  3AII A;  2JIP A;  2JIR A;  5FTJ A;  1YLE A;  2A6E D;  2BH0 A;  4RV0 A;  1NXZ A;  4QIW A;  4WFA S;  3SUK A;  2ZJP S;  3IR7 A;  3HU3 A;  2PJJ A;  1KQF A;  1CZ5 A;  1SMY D;  1HD5 A;  1OA9 A;  3ENG A;  2E2I A;  1EUY A;  2KQA A;  2E2H A;  1Q16 A;  3J7Z V;  1TWF A;  4KDL A;  3HU1 A;  4JXZ A;  1UHE A;  1Y4Z A;  5GAH W;  3SUJ A;  1PYU B;  2BE5 D;  4AON B;  4KOD A;  1N10 A;  1WC2 A;  3IR5 A;  5B6C A;  2G6G A;  5GAE W;  3X2N A;  1NYL A;  1SIW A;  3X2O A;  4KLN A;  1E61 A;  5HL7 S;  5DYG A;  4ENG A;  3X1L B;  1EU1 A;  4ZM7 A;  1R7R A;  2WB1 A;  1G8J A;  1VC3 B;  2PI8 A;  1TWA A;  5T5M D;  2G5D A;  1KQG A;  1G8K A;  1S3S A;  5GM9 A;  3PLX B;  1V6Z A;  3QWZ A;  5DM6 S;  1I3Q A;  3HKZ A;  1SFO A;  4FG4 A;  4CS0 A;  4WF9 S;  1OGY A;  2HCZ X;  1TWG A;  1E18 A;  2VPW A;  5EPP A;  2JA5 A;  3SUL A;  1I50 A;  4CRY G;  2EGW A;  3CF5 S;  1Y1V A;  2PMZ A; 
#chains in the Genus database with same CATH homology
 2NYA A;  2A6H D;  3GTJ A;  4JS7 A;  2JIO A;  2JA6 A;  1E60 A;  1H5N A;  1BW3 A;  4D7Z B;  3X2G A;  2B63 A;  1PT1 A;  4AAY A;  2KI8 A;  3QQ7 A;  2VUM A;  3X2K A;  3TM7 B;  3CQZ A;  1PT0 A;  2YU9 A;  1H0H A;  2VPZ A;  1IW7 D;  3H0G A;  1ZC1 A;  4L48 A;  2NVY A;  1OA7 A;  1PQE A;  1Y5I A;  3CF2 A;  4GA6 A;  4FFT A;  3QQ8 A;  4KDI A;  3M3G A;  1E5V A;  2C45 A;  2V45 A;  2PIC A;  2NVX A;  4FER A;  2ENG A;  1WCM A;  2PJH B;  1E32 A;  2JIM A;  1TWH A;  3X2P A;  4GA5 A;  2JA7 A;  5FTK A;  1Y1W A;  5T5I D;  1K83 A;  5DYI A;  3GTO A;  5FTM A;  3GTG A;  2E7Z A;  1DMR A;  2IV2 X;  1YNN D;  2R7Z A;  2AE0 X;  3GTK A;  2DMR A;  3IR6 A;  2A68 D;  4JP6 A;  2VPY A;  4DMR A;  1TMO A;  1QDN A;  3GTL A;  2GAE A;  3D30 A;  4NOH A;  5H4U A;  4AOK B;  1QCS A;  2VPX A;  1ZYR D;  3O5A A;  5C18 A;  4AVR A;  1L8F A;  2O5J D;  5FTN A;  5GLX A;  2CW0 D;  1CZ4 A;  3GTM A;  5C1B A;  5FTL A;  4AYB A;  3SUM A;  2YUJ A;  4JCW A;  2R92 A;  4C2M A;  4FG2 A;  2WAQ A;  3X2L A;  3X2M A;  3X2H A;  1FDI A;  1AA6 A;  2Y0S A;  3X2J A;  1WLF A;  4JP7 A;  2V3V A;  1PYQ A;  4JJO A;  1DMS A;  5GLY A;  3TIW A;  3CZB A;  5GLF A;  1FDO A;  3DMR A;  2R93 A;  4AZD A;  1R9T A;  4CRZ A;  1R27 A;  3GTQ A;  3X2I A;  1PPY A;  1AW8 B;  1PQH A;  1UHD A;  2EEO B;  3OUG A;  3HU2 A;  1BW4 A;  3FKI A;  2NAP A;  4KO8 A;  1YNJ D;  3GTP A;  3ML1 A;  1TWC A;  2JIQ A;  3QC8 A;  2A69 D;  2PNW A;  1PQF A;  1CR5 A;  2JIP A;  2JIR A;  5FTJ A;  1YLE A;  2A6E D;  2BH0 A;  4RV0 A;  4QIW A;  3SUK A;  3IR7 A;  3HU3 A;  2PJJ A;  1KQF A;  1CZ5 A;  1SMY D;  1HD5 A;  3ENG A;  1OA9 A;  2E2I A;  2KQA A;  2E2H A;  1Q16 A;  1TWF A;  4KDL A;  3HU1 A;  1UHE A;  1Y4Z A;  3SUJ A;  1PYU B;  2BE5 D;  4AON B;  4KOD A;  1N10 A;  1WC2 A;  3IR5 A;  5B6C A;  2G6G A;  3X2N A;  1SIW A;  3X2O A;  4KLN A;  1E61 A;  5DYG A;  4ENG A;  1EU1 A;  4ZM7 A;  1R7R A;  2WB1 A;  1G8J A;  1VC3 B;  2PI8 A;  1TWA A;  5T5M D;  2G5D A;  1KQG A;  1G8K A;  1S3S A;  5GM9 A;  3PLX B;  3QWZ A;  1I3Q A;  3HKZ A;  1SFO A;  4FG4 A;  4CS0 A;  1OGY A;  2HCZ X;  1TWG A;  1E18 A;  2VPW A;  5EPP A;  2JA5 A;  3SUL A;  1I50 A;  4CRY G;  1Y1V A;  2PMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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