2PJJA

E. coli lytic transglycosylase mlta-d308a in apo-1 form
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
335
structure length
335
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 94
structure length 335
sequence length 335
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2pjjA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2pjjA02
4ZM7A 2KQAA 4FFTA 1BW3A 1BW4A 1OA9A 3D30A 4JJOA 3X2LA 2PJJA 3X2NA 3X2IA 4ENGA 2HCZX 2G6GA 1N10A 4FG4A 2G5DA 3SUKA 2PI8A 5GLYA 3SUMA 3X2HA 1WC2A 3SULA 3ENGA 4JP7A 4AVRA 4JCWA 2PNWA 4L48A 2BH0A 3X2PA 2GAEA 3CZBA 3X2GA 2PICA 3X2JA 1L8FA 5GLXA 4FERA 3SUJA 3M3GA 3X2OA 5GM9A 4JS7A 4JP6A 3X2MA 3X2KA 1OA7A 4FG2A 2ENGA 1HD5A 2AE0X 5H4UA
chains in the Genus database with same CATH superfamily
4WFNS 5FTMA 1BW3A 3O5AA 2NVXA 2E2IA 4L69A 2ZJRS 1SMYD 2E7ZA 3QQ7A 2PMZA 3D30A 2YU9A 3X2LA 2NWAA 1PT0A 1Y4ZA 4C2MA 1Q16A 1EUYA 1DFUP 3X2IA 2VPYA 4WFBS 1PYUB 1OGYA 1SIWA 4AYBA 2HCZX 2DMRA 1KQGA 1VHYA 5GAGW 4D7ZB 3GTQA 3GTPA 1UDXA 2Y0SA 1WCMA 3X2HA 1GTSA 2R93A 1TWFA 4KODA 4AVRA 2R92A 4JCWA 3X2PA 3CF2A 3QC8A 3GTMA 4IO9S 4WFAS 1TWCA 1R9TA 5DM7S 3CF5S 3HKZA 5C18A 1L8FA 1KQFA 4JXZA 1O0CA 2A6ED 1ZYRD 1UHDA 1AA6A 4JP6A 1E18A 1PQFA 3X2KA 2VUMA 1NYLA 1QRSA 2JIOA 1I50A 1CZ4A 1D6KA 2Z0YA 1HD5A 2A6HD 1QTQA 4IOAS 3FKIA 5H4UA 5FTLA 1Y5IA 2NAPA 3IR5A 4FFTA 4WCES 4JXXA 4RV0A 1GTRA 1EU1A 2V45A 1CZ5A 1Z85A 1FEUA 2B63A 4ENGA 2NVYA 5IZNA 1TWGA 1ZC1A 5DYGA 4NOHA 1Y1WA 2JIMA 2G6GA 2ZJQS 1WLFA 4AAYA 1R27A 2C45A 3DMRA 3PLXB 3SUKA 3HU3A 4H3SA 1EUQA 3GTOA 2ZJPS 4P2BA 4CRYG 3SULA 4JP7A 1YLEA 1K83A 2EGVA 2PNWA 4J3CA 2BH0A 1PPYA 3CZBA 3X2GA 1PQHA 2PICA 1G8KA 1O0BA 1DMRA 2JIPA 1V6ZA 5DYIA 4E8BA 3J7ZV 1S3SA 3H0GA 4FERA 5C1BA 4KDIA 1TWAA 1YNND 2IV2X 4JS7A 3GTLA 2A68D 3X2MA 1IW7D 3GTKA 1DMSA 4CRZA 1EXDA 3ML1A 2YUJA 2ENGA 1H5NA 1QRTA 1VC3B 2A69D 1BW4A 1QRUA 2JA6A 5BNZA 4KLNA 4QIWA 1B75A 5GAHW 3IR7A 2O5JD 2JA5A 5FTKA 4H4KA 1N10A 2RD2A 5FTNA 2G5DA 1PQEA 1AW8B 2PI8A 4AONB 4CS0A 2R7ZA 5HL7S 4JYZA 1E60A 4UY88 1E32A 1WC2A 5JVGS 1PT1A 3W2VB 3ENGA 5EPPA 3IR6A 2HZ7A 2GAEA 5T5ID 1E61A 3QWZA 3KW2A 5GLXA 3AIIA 3SUJA 3X2OA 1CR5A 4WF9S 3HU1A 4KO8A 3PIPS 1H0HA 2CW0D 5B6CA 1OA7A 3GTJA 2CX8A 5GADW 2WB1A 4KDLA 1NXZA 4AOKB 2EGWA 4U67S 1E5VA 1Y1VA 1TWHA 2BE5D 2KQAA 1UHEA 2JIQA 2WAQA 4ZM7A 3W2WB 3TM7B 1OA9A 1QDNA 2EEOB 4JJOA 5GAEW 3X1LB 4DMRA 2PJHB 2PJJA 2NYAA 3X2NA 2RE8A 1ZJWA 4GA5A 5DM6S 2E2HA 1FDIA 1QCSA 4AZDA 4FG4A 4IOCS 5GLYA 1YNJD 3SUMA 4GA6A 1R7RA 3HU2A 1I3QA 3QQ8A 1G8JA 4L48A 5FTJA 2JIRA 3TIWA 2V3VA 2JA7A 5JVHS 3CQZA 3OUGA 3X2JA 3DLLS 2VPZA 4V194 3M3GA 3GTGA 2KI8A 5GM9A 3PIOS 5T5MD 2VPWA 5GLFA 4FG2A 1TMOA 2VPXA 1PYQA 1VHKA 1SFOA 1FDOA 2AE0X
chains in the Genus database with same CATH topology
5FTMA 1BW3A 3O5AA 2NVXA 2E2IA 1SMYD 2E7ZA 3QQ7A 3D30A 2PMZA 2YU9A 3X2LA 1PT0A 1Y4ZA 4C2MA 1Q16A 3X2IA 2VPYA 1PYUB 1OGYA 1SIWA 4AYBA 2HCZX 2DMRA 1KQGA 4D7ZB 3GTQA 3GTPA 2Y0SA 3X2HA 1WCMA 2R93A 1TWFA 4AVRA 4KODA 2R92A 4JCWA 3X2PA 3CF2A 3QC8A 3GTMA 1TWCA 1R9TA 3HKZA 5C18A 1L8FA 1KQFA 2A6ED 1ZYRD 1UHDA 1AA6A 4JP6A 1E18A 3X2KA 1PQFA 2VUMA 2JIOA 1I50A 1CZ4A 1HD5A 2A6HD 5H4UA 3FKIA 5FTLA 4FFTA 1Y5IA 2NAPA 3IR5A 4RV0A 1EU1A 2V45A 1CZ5A 2B63A 4ENGA 2NVYA 1TWGA 1ZC1A 5DYGA 4NOHA 1Y1WA 2JIMA 2G6GA 1WLFA 4AAYA 1R27A 3SUKA 2C45A 3DMRA 3PLXB 3HU3A 3GTOA 4CRYG 3SULA 4JP7A 1YLEA 1K83A 2PNWA 2BH0A 1PPYA 3CZBA 3X2GA 1PQHA 2PICA 1G8KA 1DMRA 2JIPA 5DYIA 1S3SA 4FERA 3H0GA 5C1BA 4KDIA 1TWAA 1YNND 2IV2X 4JS7A 3GTLA 2A68D 3X2MA 1IW7D 3GTKA 1DMSA 4CRZA 3ML1A 2YUJA 2ENGA 1H5NA 1VC3B 2A69D 1BW4A 2JA6A 4KLNA 4QIWA 3IR7A 2O5JD 2JA5A 5FTKA 1N10A 5FTNA 2G5DA 1PQEA 2PI8A 1AW8B 4AONB 4CS0A 2R7ZA 1E60A 1E32A 1WC2A 1PT1A 3ENGA 5EPPA 3IR6A 2GAEA 5T5ID 1E61A 3QWZA 5GLXA 3SUJA 3X2OA 1CR5A 3HU1A 4KO8A 1H0HA 2CW0D 5B6CA 1OA7A 3GTJA 2WB1A 4KDLA 4AOKB 1E5VA 1Y1VA 4ZM7A 2KQAA 1TWHA 1UHEA 2BE5D 2JIQA 2WAQA 3TM7B 1OA9A 1QDNA 4JJOA 2EEOB 4DMRA 2PJJA 3X2NA 2NYAA 2PJHB 4GA5A 2E2HA 1FDIA 1QCSA 4AZDA 4FG4A 5GLYA 1YNJD 3SUMA 4GA6A 1R7RA 3HU2A 1I3QA 3QQ8A 4L48A 1G8JA 5FTJA 2JIRA 3TIWA 2V3VA 2JA7A 3CQZA 3OUGA 3X2JA 2VPZA 3M3GA 3GTGA 5GM9A 2KI8A 5T5MD 2VPWA 5GLFA 4FG2A 1TMOA 2VPXA 1PYQA 1SFOA 1FDOA 2AE0X
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZM7 A;  2KQA A;  4FFT A;  1BW3 A;  1BW4 A;  1OA9 A;  3D30 A;  4JJO A;  3X2L A;  2PJJ A;  3X2N A;  3X2I A;  4ENG A;  2HCZ X;  2G6G A;  1N10 A;  4FG4 A;  2G5D A;  3SUK A;  2PI8 A;  5GLY A;  3SUM A;  3X2H A;  1WC2 A;  3SUL A;  3ENG A;  4JP7 A;  4AVR A;  4JCW A;  2PNW A;  4L48 A;  2BH0 A;  3X2P A;  2GAE A;  3CZB A;  3X2G A;  2PIC A;  3X2J A;  1L8F A;  5GLX A;  4FER A;  3SUJ A;  3M3G A;  3X2O A;  5GM9 A;  4JS7 A;  4JP6 A;  3X2M A;  3X2K A;  1OA7 A;  4FG2 A;  2ENG A;  1HD5 A;  2AE0 X;  5H4U A; 
#chains in the Genus database with same CATH topology
 4WFN S;  5FTM A;  1BW3 A;  3O5A A;  2NVX A;  2E2I A;  4L69 A;  2ZJR S;  1SMY D;  2E7Z A;  3QQ7 A;  2PMZ A;  3D30 A;  2YU9 A;  3X2L A;  2NWA A;  1PT0 A;  1Y4Z A;  4C2M A;  1Q16 A;  1EUY A;  1DFU P;  3X2I A;  2VPY A;  4WFB S;  1PYU B;  1OGY A;  1SIW A;  4AYB A;  2HCZ X;  2DMR A;  1KQG A;  1VHY A;  5GAG W;  4D7Z B;  3GTQ A;  3GTP A;  1UDX A;  2Y0S A;  1WCM A;  3X2H A;  1GTS A;  2R93 A;  1TWF A;  4KOD A;  4AVR A;  2R92 A;  4JCW A;  3X2P A;  3CF2 A;  3QC8 A;  3GTM A;  4IO9 S;  4WFA S;  1TWC A;  1R9T A;  5DM7 S;  3CF5 S;  3HKZ A;  5C18 A;  1L8F A;  1KQF A;  4JXZ A;  1O0C A;  2A6E D;  1ZYR D;  1UHD A;  1AA6 A;  4JP6 A;  1E18 A;  1PQF A;  3X2K A;  2VUM A;  1NYL A;  1QRS A;  2JIO A;  1I50 A;  1CZ4 A;  1D6K A;  2Z0Y A;  1HD5 A;  2A6H D;  1QTQ A;  4IOA S;  3FKI A;  5H4U A;  5FTL A;  1Y5I A;  2NAP A;  3IR5 A;  4FFT A;  4WCE S;  4JXX A;  4RV0 A;  1GTR A;  1EU1 A;  2V45 A;  1CZ5 A;  1Z85 A;  1FEU A;  2B63 A;  4ENG A;  2NVY A;  5IZN A;  1TWG A;  1ZC1 A;  5DYG A;  4NOH A;  1Y1W A;  2JIM A;  2G6G A;  2ZJQ S;  1WLF A;  4AAY A;  1R27 A;  2C45 A;  3DMR A;  3PLX B;  3SUK A;  3HU3 A;  4H3S A;  1EUQ A;  3GTO A;  2ZJP S;  4P2B A;  4CRY G;  3SUL A;  4JP7 A;  1YLE A;  1K83 A;  2EGV A;  2PNW A;  4J3C A;  2BH0 A;  1PPY A;  3CZB A;  3X2G A;  1PQH A;  2PIC A;  1G8K A;  1O0B A;  1DMR A;  2JIP A;  1V6Z A;  5DYI A;  4E8B A;  3J7Z V;  1S3S A;  3H0G A;  4FER A;  5C1B A;  4KDI A;  1TWA A;  1YNN D;  2IV2 X;  4JS7 A;  3GTL A;  2A68 D;  3X2M A;  1IW7 D;  3GTK A;  1DMS A;  4CRZ A;  1EXD A;  3ML1 A;  2YUJ A;  2ENG A;  1H5N A;  1QRT A;  1VC3 B;  2A69 D;  1BW4 A;  1QRU A;  2JA6 A;  5BNZ A;  4KLN A;  4QIW A;  1B75 A;  5GAH W;  3IR7 A;  2O5J D;  2JA5 A;  5FTK A;  4H4K A;  1N10 A;  2RD2 A;  5FTN A;  2G5D A;  1PQE A;  1AW8 B;  2PI8 A;  4AON B;  4CS0 A;  2R7Z A;  5HL7 S;  4JYZ A;  1E60 A;  4UY8 8;  1E32 A;  1WC2 A;  5JVG S;  1PT1 A;  3W2V B;  3ENG A;  5EPP A;  3IR6 A;  2HZ7 A;  2GAE A;  5T5I D;  1E61 A;  3QWZ A;  3KW2 A;  5GLX A;  3AII A;  3SUJ A;  3X2O A;  1CR5 A;  4WF9 S;  3HU1 A;  4KO8 A;  3PIP S;  1H0H A;  2CW0 D;  5B6C A;  1OA7 A;  3GTJ A;  2CX8 A;  5GAD W;  2WB1 A;  4KDL A;  1NXZ A;  4AOK B;  2EGW A;  4U67 S;  1E5V A;  1Y1V A;  1TWH A;  2BE5 D;  2KQA A;  1UHE A;  2JIQ A;  2WAQ A;  4ZM7 A;  3W2W B;  3TM7 B;  1OA9 A;  1QDN A;  2EEO B;  4JJO A;  5GAE W;  3X1L B;  4DMR A;  2PJH B;  2PJJ A;  2NYA A;  3X2N A;  2RE8 A;  1ZJW A;  4GA5 A;  5DM6 S;  2E2H A;  1FDI A;  1QCS A;  4AZD A;  4FG4 A;  4IOC S;  5GLY A;  1YNJ D;  3SUM A;  4GA6 A;  1R7R A;  3HU2 A;  1I3Q A;  3QQ8 A;  1G8J A;  4L48 A;  5FTJ A;  2JIR A;  3TIW A;  2V3V A;  2JA7 A;  5JVH S;  3CQZ A;  3OUG A;  3X2J A;  3DLL S;  2VPZ A;  4V19 4;  3M3G A;  3GTG A;  2KI8 A;  5GM9 A;  3PIO S;  5T5M D;  2VPW A;  5GLF A;  4FG2 A;  1TMO A;  2VPX A;  1PYQ A;  1VHK A;  1SFO A;  1FDO A;  2AE0 X; 
#chains in the Genus database with same CATH homology
 5FTM A;  1BW3 A;  3O5A A;  2NVX A;  2E2I A;  1SMY D;  2E7Z A;  3QQ7 A;  3D30 A;  2PMZ A;  2YU9 A;  3X2L A;  1PT0 A;  1Y4Z A;  4C2M A;  1Q16 A;  3X2I A;  2VPY A;  1PYU B;  1OGY A;  1SIW A;  4AYB A;  2HCZ X;  2DMR A;  1KQG A;  4D7Z B;  3GTQ A;  3GTP A;  2Y0S A;  3X2H A;  1WCM A;  2R93 A;  1TWF A;  4AVR A;  4KOD A;  2R92 A;  4JCW A;  3X2P A;  3CF2 A;  3QC8 A;  3GTM A;  1TWC A;  1R9T A;  3HKZ A;  5C18 A;  1L8F A;  1KQF A;  2A6E D;  1ZYR D;  1UHD A;  1AA6 A;  4JP6 A;  1E18 A;  3X2K A;  1PQF A;  2VUM A;  2JIO A;  1I50 A;  1CZ4 A;  1HD5 A;  2A6H D;  5H4U A;  3FKI A;  5FTL A;  4FFT A;  1Y5I A;  2NAP A;  3IR5 A;  4RV0 A;  1EU1 A;  2V45 A;  1CZ5 A;  2B63 A;  4ENG A;  2NVY A;  1TWG A;  1ZC1 A;  5DYG A;  4NOH A;  1Y1W A;  2JIM A;  2G6G A;  1WLF A;  4AAY A;  1R27 A;  3SUK A;  2C45 A;  3DMR A;  3PLX B;  3HU3 A;  3GTO A;  4CRY G;  3SUL A;  4JP7 A;  1YLE A;  1K83 A;  2PNW A;  2BH0 A;  1PPY A;  3CZB A;  3X2G A;  1PQH A;  2PIC A;  1G8K A;  1DMR A;  2JIP A;  5DYI A;  1S3S A;  4FER A;  3H0G A;  5C1B A;  4KDI A;  1TWA A;  1YNN D;  2IV2 X;  4JS7 A;  3GTL A;  2A68 D;  3X2M A;  1IW7 D;  3GTK A;  1DMS A;  4CRZ A;  3ML1 A;  2YUJ A;  2ENG A;  1H5N A;  1VC3 B;  2A69 D;  1BW4 A;  2JA6 A;  4KLN A;  4QIW A;  3IR7 A;  2O5J D;  2JA5 A;  5FTK A;  1N10 A;  5FTN A;  2G5D A;  1PQE A;  2PI8 A;  1AW8 B;  4AON B;  4CS0 A;  2R7Z A;  1E60 A;  1E32 A;  1WC2 A;  1PT1 A;  3ENG A;  5EPP A;  3IR6 A;  2GAE A;  5T5I D;  1E61 A;  3QWZ A;  5GLX A;  3SUJ A;  3X2O A;  1CR5 A;  3HU1 A;  4KO8 A;  1H0H A;  2CW0 D;  5B6C A;  1OA7 A;  3GTJ A;  2WB1 A;  4KDL A;  4AOK B;  1E5V A;  1Y1V A;  4ZM7 A;  2KQA A;  1TWH A;  1UHE A;  2BE5 D;  2JIQ A;  2WAQ A;  3TM7 B;  1OA9 A;  1QDN A;  4JJO A;  2EEO B;  4DMR A;  2PJJ A;  3X2N A;  2NYA A;  2PJH B;  4GA5 A;  2E2H A;  1FDI A;  1QCS A;  4AZD A;  4FG4 A;  5GLY A;  1YNJ D;  3SUM A;  4GA6 A;  1R7R A;  3HU2 A;  1I3Q A;  3QQ8 A;  4L48 A;  1G8J A;  5FTJ A;  2JIR A;  3TIW A;  2V3V A;  2JA7 A;  3CQZ A;  3OUG A;  3X2J A;  2VPZ A;  3M3G A;  3GTG A;  5GM9 A;  2KI8 A;  5T5M D;  2VPW A;  5GLF A;  4FG2 A;  1TMO A;  2VPX A;  1PYQ A;  1SFO A;  1FDO A;  2AE0 X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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