2AE0X

Crystal structure of mlta from escherichia coli reveals a unique lytic transglycosylase fold
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
335
structure length
335
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of MltA from Escherichia coli Reveals a Unique Lytic Transglycosylase Fold
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 95
structure length 335
sequence length 335
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2005-07-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF03562 MltA MltA specific insert domain
X PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2ae0X01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2ae0X02
1HD5A 4ENGA 2GAEA 3X2MA 1OA7A 2PICA 4FG2A 3X2LA 4FG4A 4L48A 4JP6A 4JS7A 5H4UA 3SULA 3CZBA 3SUJA 3X2KA 2AE0X 5GLXA 2G6GA 4JCWA 2PNWA 1N10A 3ENGA 2PJJA 2HCZX 3X2GA 4AVRA 5GM9A 3SUKA 1OA9A 1L8FA 2G5DA 5GLYA 3X2OA 4FFTA 3X2HA 3X2JA 4ZM7A 3X2NA 4JJOA 3X2IA 1BW4A 4JP7A 3SUMA 2PI8A 3D30A 3M3GA 4FERA 3X2PA 2KQAA 2BH0A 1BW3A 2ENGA 1WC2A
chains in the Genus database with same CATH superfamily
3J7ZV 3TIWA 4U67S 5C1BA 4UY88 1O0CA 4V194 5BNZA 3QQ8A 2JA5A 1SFOA 1NXZA 1I50A 1UDXA 2R92A 3GTQA 3SUJA 1CZ5A 5GAGW 4KDLA 1I3QA 1CR5A 2ZJPS 1TWAA 2V45A 1ZYRD 2A69D 3FKIA 2G6GA 3GTKA 2PNWA 3ENGA 3X2GA 1DMSA 4IOAS 4KDIA 4IOCS 5GM9A 5FTLA 3GTJA 3X2JA 2G5DA 2JIRA 3HU2A 2CW0D 4FFTA 5GAHW 2RD2A 3X2NA 4JJOA 4IO9S 4P2BA 3SUMA 2R93A 4JXZA 2NYAA 5DM7S 2BH0A 2B63A 4H4KA 1QCSA 4CS0A 4AZDA 2Y0SA 1VHKA 2NAPA 4GA6A 1AA6A 5GADW 1SIWA 2IV2X 4H3SA 5JVHS 1Y1VA 1HD5A 1E32A 4NOHA 4ENGA 1E60A 4KODA 4FG2A 2PICA 1FDOA 3CF2A 2BE5D 1UHEA 1PT1A 1ZC1A 3X2LA 4L48A 1PT0A 5H4UA 3PLXB 4JYZA 1TWHA 2A68D 4L69A 2R7ZA 2EEOB 1H0HA 1TWFA 4WFAS 1PQEA 1N10A 2JIOA 2JIQA 2PJJA 4CRZA 1KQGA 3SUKA 3GTMA 1Y5IA 1OA9A 1L8FA 2JIMA 3QWZA 3X2OA 2Z0YA 2YUJA 3X2HA 4DMRA 2CX8A 5JVGS 2WB1A 1R7RA 4JP7A 3D30A 4WFBS 1GTSA 1KQFA 3X1LB 2EGVA 4QIWA 4RV0A 4WF9S 3GTPA 1FDIA 5GLFA 2VPYA 1WC2A 1H5NA 2JA6A 5FTJA 4KLNA 3CF5S 3KW2A 1TMOA 3ML1A 3DMRA 5FTMA 1PQHA 3GTOA 1FEUA 1QTQA 1G8KA 1OA7A 3IR5A 3TM7B 1QRSA 4GA5A 4KO8A 5FTKA 4JP6A 4CRYG 2NWAA 1QRUA 1Z85A 3SULA 1E5VA 1YNJD 3CZBA 2EGWA 1D6KA 2AE0X 3W2WB 3IR6A 2ZJRS 1IW7D 1TWCA 4AYBA 3IR7A 2E2IA 2HCZX 5DYGA 4AAYA 4J3CA 4WCES 5GLYA 4ZM7A 1YLEA 1Y1WA 1BW4A 4JXXA 1EUYA 3OUGA 5B6CA 1DFUP 5GAEW 3X2PA 4D7ZB 1R27A 4E8BA 1SMYD 2ZJQS 1VHYA 1PPYA 2YU9A 1QDNA 2DMRA 1AW8B 2ENGA 4AONB 1VC3B 1Y4ZA 2WAQA 1O0BA 5T5ID 1K83A 2NVYA 1DMRA 5EPPA 3CQZA 1PYQA 4WFNS 3GTLA 3GTGA 2E2HA 5DM6S 2JIPA 2VPXA 3PIPS 1UHDA 2C45A 2GAEA 3X2MA 3O5AA 5C18A 1R9TA 5FTNA 1GTRA 2PJHB 4FG4A 2NVXA 1E18A 2VPWA 1EU1A 4JS7A 5IZNA 1QRTA 1B75A 1WLFA 3X2KA 3HKZA 1EUQA 1S3SA 1Q16A 1YNND 3HU3A 3QC8A 2RE8A 3W2VB 5GLXA 3DLLS 4JCWA 1E61A 1TWGA 4C2MA 2A6ED 2PMZA 4AVRA 2JA7A 3QQ7A 2E7ZA 2V3VA 3HU1A 2VPZA 3H0GA 3X2IA 1V6ZA 2PI8A 3M3GA 3AIIA 2VUMA 1G8JA 4FERA 1NYLA 2KQAA 2KI8A 1CZ4A 3PIOS 1WCMA 1PYUB 1PQFA 5HL7S 1BW3A 1OGYA 1EXDA 1ZJWA 2O5JD 5T5MD 5DYIA 2A6HD 2HZ7A 4AOKB
chains in the Genus database with same CATH topology
3TIWA 5C1BA 3QQ8A 2JA5A 1SFOA 1I50A 2R92A 3GTQA 3SUJA 1CZ5A 4KDLA 1I3QA 1CR5A 1TWAA 2V45A 1ZYRD 2A69D 3FKIA 2G6GA 3GTKA 2PNWA 3ENGA 3X2GA 1DMSA 4KDIA 5GM9A 5FTLA 3GTJA 3X2JA 2G5DA 2JIRA 3HU2A 4FFTA 2CW0D 3X2NA 4JJOA 3SUMA 2R93A 2NYAA 2BH0A 2B63A 1QCSA 4CS0A 4AZDA 2Y0SA 2NAPA 4GA6A 1AA6A 1SIWA 2IV2X 1Y1VA 1HD5A 4ENGA 1E32A 4NOHA 1E60A 4KODA 4FG2A 2PICA 3X2LA 1FDOA 2BE5D 1UHEA 1PT1A 1ZC1A 3CF2A 4L48A 1PT0A 5H4UA 3PLXB 1TWHA 2A68D 2R7ZA 2EEOB 1H0HA 1TWFA 1PQEA 1N10A 2JIOA 2JIQA 2PJJA 4CRZA 1KQGA 3SUKA 3GTMA 1Y5IA 1OA9A 1L8FA 2JIMA 3X2OA 3QWZA 3X2HA 2YUJA 4DMRA 2WB1A 4JP7A 1R7RA 3D30A 1KQFA 4QIWA 4RV0A 3GTPA 1FDIA 5GLFA 2VPYA 1H5NA 1WC2A 2JA6A 5FTJA 4KLNA 1TMOA 3ML1A 3DMRA 5FTMA 1PQHA 3GTOA 1G8KA 1OA7A 3IR5A 3TM7B 4GA5A 4KO8A 5FTKA 4JP6A 4CRYG 3SULA 1E5VA 3CZBA 1YNJD 2AE0X 3IR6A 1IW7D 1TWCA 4AYBA 3IR7A 2E2IA 2HCZX 5DYGA 4AAYA 5GLYA 4ZM7A 1BW4A 1YLEA 1Y1WA 3OUGA 5B6CA 3X2PA 4D7ZB 1R27A 1SMYD 1PPYA 2YU9A 1QDNA 2DMRA 1AW8B 2ENGA 4AONB 1VC3B 1Y4ZA 2WAQA 5T5ID 1K83A 2NVYA 1DMRA 5EPPA 3CQZA 1PYQA 3GTLA 3GTGA 2E2HA 2JIPA 2VPXA 1UHDA 2GAEA 2C45A 3X2MA 3O5AA 5C18A 1R9TA 5FTNA 2PJHB 4FG4A 2NVXA 1E18A 2VPWA 4JS7A 1EU1A 3X2KA 1WLFA 3HKZA 1S3SA 1Q16A 1YNND 3HU3A 3QC8A 5GLXA 4JCWA 1E61A 1TWGA 4C2MA 2A6ED 4AVRA 2PMZA 2JA7A 3QQ7A 2E7ZA 2V3VA 3HU1A 2VPZA 3H0GA 3X2IA 2PI8A 3M3GA 2VUMA 1G8JA 4FERA 2KQAA 2KI8A 1CZ4A 1WCMA 1PYUB 1PQFA 1BW3A 1OGYA 2O5JD 5T5MD 5DYIA 2A6HD 4AOKB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HD5 A;  4ENG A;  2GAE A;  3X2M A;  1OA7 A;  2PIC A;  4FG2 A;  3X2L A;  4FG4 A;  4L48 A;  4JP6 A;  4JS7 A;  5H4U A;  3SUL A;  3CZB A;  3SUJ A;  3X2K A;  2AE0 X;  5GLX A;  2G6G A;  4JCW A;  2PNW A;  1N10 A;  3ENG A;  2PJJ A;  2HCZ X;  3X2G A;  4AVR A;  5GM9 A;  3SUK A;  1OA9 A;  1L8F A;  2G5D A;  5GLY A;  3X2O A;  4FFT A;  3X2H A;  3X2J A;  4ZM7 A;  3X2N A;  4JJO A;  3X2I A;  1BW4 A;  4JP7 A;  3SUM A;  2PI8 A;  3D30 A;  3M3G A;  4FER A;  3X2P A;  2KQA A;  2BH0 A;  1BW3 A;  2ENG A;  1WC2 A; 
#chains in the Genus database with same CATH topology
 3J7Z V;  3TIW A;  4U67 S;  5C1B A;  4UY8 8;  1O0C A;  4V19 4;  5BNZ A;  3QQ8 A;  2JA5 A;  1SFO A;  1NXZ A;  1I50 A;  1UDX A;  2R92 A;  3GTQ A;  3SUJ A;  1CZ5 A;  5GAG W;  4KDL A;  1I3Q A;  1CR5 A;  2ZJP S;  1TWA A;  2V45 A;  1ZYR D;  2A69 D;  3FKI A;  2G6G A;  3GTK A;  2PNW A;  3ENG A;  3X2G A;  1DMS A;  4IOA S;  4KDI A;  4IOC S;  5GM9 A;  5FTL A;  3GTJ A;  3X2J A;  2G5D A;  2JIR A;  3HU2 A;  2CW0 D;  4FFT A;  5GAH W;  2RD2 A;  3X2N A;  4JJO A;  4IO9 S;  4P2B A;  3SUM A;  2R93 A;  4JXZ A;  2NYA A;  5DM7 S;  2BH0 A;  2B63 A;  4H4K A;  1QCS A;  4CS0 A;  4AZD A;  2Y0S A;  1VHK A;  2NAP A;  4GA6 A;  1AA6 A;  5GAD W;  1SIW A;  2IV2 X;  4H3S A;  5JVH S;  1Y1V A;  1HD5 A;  1E32 A;  4NOH A;  4ENG A;  1E60 A;  4KOD A;  4FG2 A;  2PIC A;  1FDO A;  3CF2 A;  2BE5 D;  1UHE A;  1PT1 A;  1ZC1 A;  3X2L A;  4L48 A;  1PT0 A;  5H4U A;  3PLX B;  4JYZ A;  1TWH A;  2A68 D;  4L69 A;  2R7Z A;  2EEO B;  1H0H A;  1TWF A;  4WFA S;  1PQE A;  1N10 A;  2JIO A;  2JIQ A;  2PJJ A;  4CRZ A;  1KQG A;  3SUK A;  3GTM A;  1Y5I A;  1OA9 A;  1L8F A;  2JIM A;  3QWZ A;  3X2O A;  2Z0Y A;  2YUJ A;  3X2H A;  4DMR A;  2CX8 A;  5JVG S;  2WB1 A;  1R7R A;  4JP7 A;  3D30 A;  4WFB S;  1GTS A;  1KQF A;  3X1L B;  2EGV A;  4QIW A;  4RV0 A;  4WF9 S;  3GTP A;  1FDI A;  5GLF A;  2VPY A;  1WC2 A;  1H5N A;  2JA6 A;  5FTJ A;  4KLN A;  3CF5 S;  3KW2 A;  1TMO A;  3ML1 A;  3DMR A;  5FTM A;  1PQH A;  3GTO A;  1FEU A;  1QTQ A;  1G8K A;  1OA7 A;  3IR5 A;  3TM7 B;  1QRS A;  4GA5 A;  4KO8 A;  5FTK A;  4JP6 A;  4CRY G;  2NWA A;  1QRU A;  1Z85 A;  3SUL A;  1E5V A;  1YNJ D;  3CZB A;  2EGW A;  1D6K A;  2AE0 X;  3W2W B;  3IR6 A;  2ZJR S;  1IW7 D;  1TWC A;  4AYB A;  3IR7 A;  2E2I A;  2HCZ X;  5DYG A;  4AAY A;  4J3C A;  4WCE S;  5GLY A;  4ZM7 A;  1YLE A;  1Y1W A;  1BW4 A;  4JXX A;  1EUY A;  3OUG A;  5B6C A;  1DFU P;  5GAE W;  3X2P A;  4D7Z B;  1R27 A;  4E8B A;  1SMY D;  2ZJQ S;  1VHY A;  1PPY A;  2YU9 A;  1QDN A;  2DMR A;  1AW8 B;  2ENG A;  4AON B;  1VC3 B;  1Y4Z A;  2WAQ A;  1O0B A;  5T5I D;  1K83 A;  2NVY A;  1DMR A;  5EPP A;  3CQZ A;  1PYQ A;  4WFN S;  3GTL A;  3GTG A;  2E2H A;  5DM6 S;  2JIP A;  2VPX A;  3PIP S;  1UHD A;  2C45 A;  2GAE A;  3X2M A;  3O5A A;  5C18 A;  1R9T A;  5FTN A;  1GTR A;  2PJH B;  4FG4 A;  2NVX A;  1E18 A;  2VPW A;  1EU1 A;  4JS7 A;  5IZN A;  1QRT A;  1B75 A;  1WLF A;  3X2K A;  3HKZ A;  1EUQ A;  1S3S A;  1Q16 A;  1YNN D;  3HU3 A;  3QC8 A;  2RE8 A;  3W2V B;  5GLX A;  3DLL S;  4JCW A;  1E61 A;  1TWG A;  4C2M A;  2A6E D;  2PMZ A;  4AVR A;  2JA7 A;  3QQ7 A;  2E7Z A;  2V3V A;  3HU1 A;  2VPZ A;  3H0G A;  3X2I A;  1V6Z A;  2PI8 A;  3M3G A;  3AII A;  2VUM A;  1G8J A;  4FER A;  1NYL A;  2KQA A;  2KI8 A;  1CZ4 A;  3PIO S;  1WCM A;  1PYU B;  1PQF A;  5HL7 S;  1BW3 A;  1OGY A;  1EXD A;  1ZJW A;  2O5J D;  5T5M D;  5DYI A;  2A6H D;  2HZ7 A;  4AOK B; 
#chains in the Genus database with same CATH homology
 3TIW A;  5C1B A;  3QQ8 A;  2JA5 A;  1SFO A;  1I50 A;  2R92 A;  3GTQ A;  3SUJ A;  1CZ5 A;  4KDL A;  1I3Q A;  1CR5 A;  1TWA A;  2V45 A;  1ZYR D;  2A69 D;  3FKI A;  2G6G A;  3GTK A;  2PNW A;  3ENG A;  3X2G A;  1DMS A;  4KDI A;  5GM9 A;  5FTL A;  3GTJ A;  3X2J A;  2G5D A;  2JIR A;  3HU2 A;  4FFT A;  2CW0 D;  3X2N A;  4JJO A;  3SUM A;  2R93 A;  2NYA A;  2BH0 A;  2B63 A;  1QCS A;  4CS0 A;  4AZD A;  2Y0S A;  2NAP A;  4GA6 A;  1AA6 A;  1SIW A;  2IV2 X;  1Y1V A;  1HD5 A;  4ENG A;  1E32 A;  4NOH A;  1E60 A;  4KOD A;  4FG2 A;  2PIC A;  3X2L A;  1FDO A;  2BE5 D;  1UHE A;  1PT1 A;  1ZC1 A;  3CF2 A;  4L48 A;  1PT0 A;  5H4U A;  3PLX B;  1TWH A;  2A68 D;  2R7Z A;  2EEO B;  1H0H A;  1TWF A;  1PQE A;  1N10 A;  2JIO A;  2JIQ A;  2PJJ A;  4CRZ A;  1KQG A;  3SUK A;  3GTM A;  1Y5I A;  1OA9 A;  1L8F A;  2JIM A;  3X2O A;  3QWZ A;  3X2H A;  2YUJ A;  4DMR A;  2WB1 A;  4JP7 A;  1R7R A;  3D30 A;  1KQF A;  4QIW A;  4RV0 A;  3GTP A;  1FDI A;  5GLF A;  2VPY A;  1H5N A;  1WC2 A;  2JA6 A;  5FTJ A;  4KLN A;  1TMO A;  3ML1 A;  3DMR A;  5FTM A;  1PQH A;  3GTO A;  1G8K A;  1OA7 A;  3IR5 A;  3TM7 B;  4GA5 A;  4KO8 A;  5FTK A;  4JP6 A;  4CRY G;  3SUL A;  1E5V A;  3CZB A;  1YNJ D;  2AE0 X;  3IR6 A;  1IW7 D;  1TWC A;  4AYB A;  3IR7 A;  2E2I A;  2HCZ X;  5DYG A;  4AAY A;  5GLY A;  4ZM7 A;  1BW4 A;  1YLE A;  1Y1W A;  3OUG A;  5B6C A;  3X2P A;  4D7Z B;  1R27 A;  1SMY D;  1PPY A;  2YU9 A;  1QDN A;  2DMR A;  1AW8 B;  2ENG A;  4AON B;  1VC3 B;  1Y4Z A;  2WAQ A;  5T5I D;  1K83 A;  2NVY A;  1DMR A;  5EPP A;  3CQZ A;  1PYQ A;  3GTL A;  3GTG A;  2E2H A;  2JIP A;  2VPX A;  1UHD A;  2GAE A;  2C45 A;  3X2M A;  3O5A A;  5C18 A;  1R9T A;  5FTN A;  2PJH B;  4FG4 A;  2NVX A;  1E18 A;  2VPW A;  4JS7 A;  1EU1 A;  3X2K A;  1WLF A;  3HKZ A;  1S3S A;  1Q16 A;  1YNN D;  3HU3 A;  3QC8 A;  5GLX A;  4JCW A;  1E61 A;  1TWG A;  4C2M A;  2A6E D;  4AVR A;  2PMZ A;  2JA7 A;  3QQ7 A;  2E7Z A;  2V3V A;  3HU1 A;  2VPZ A;  3H0G A;  3X2I A;  2PI8 A;  3M3G A;  2VUM A;  1G8J A;  4FER A;  2KQA A;  2KI8 A;  1CZ4 A;  1WCM A;  1PYU B;  1PQF A;  1BW3 A;  1OGY A;  2O5J D;  5T5M D;  5DYI A;  2A6H D;  4AOK B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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