2GAEA

Crystal structure of mlta from e. coli
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
333
structure length
333
Chain Sequence
KPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIGPEAGHRAGWYNHYGRVWVLKTA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of the Lytic Transglycosylase MltA from N.gonorrhoeae and E.coli: Insights into Interdomain Movements and Substrate Binding.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 89
structure length 333
sequence length 333
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2006-03-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2gaeA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2gaeA02
2GAEA 4JCWA 4JP6A 1OA9A 4FG2A 1OA7A 4JJOA 3X2LA 1HD5A 2PJJA 2HCZX 2G5DA 2PICA 2G6GA 3M3GA 5GLYA 4FFTA 3SUKA 3X2KA 3X2JA 3SUMA 4ENGA 3ENGA 3X2IA 4FERA 4ZM7A 5GM9A 3SULA 2AE0X 1BW4A 4JP7A 3X2HA 1BW3A 4AVRA 3X2OA 4L48A 1L8FA 1WC2A 2PI8A 4JS7A 5GLXA 1N10A 3X2MA 3X2GA 3CZBA 2PNWA 4FG4A 2BH0A 5H4UA 3X2NA 3D30A 2ENGA 3X2PA 2KQAA 3SUJA
chains in the Genus database with same CATH superfamily
1S3SA 2GAEA 2VPZA 4JP6A 1CR5A 1R7RA 1QDNA 1H0HA 3IR5A 1AA6A 1PT1A 3PIOS 4FG2A 4GA5A 3X2LA 4U67S 2Z0YA 2WAQA 4IOCS 2JA6A 1NXZA 2HCZX 2PICA 3O5AA 2G6GA 5DM6S 1QRUA 5GLYA 4WF9S 1WCMA 4CS0A 1WLFA 4GA6A 3GTKA 3W2WB 2C45A 2RD2A 1DFUP 2NVYA 3TIWA 1PQFA 3HKZA 3QWZA 3X2KA 3X2JA 3H0GA 4ENGA 2NYAA 5DYGA 3X2IA 1R27A 2VPWA 2E7ZA 1I3QA 2JIOA 1TMOA 1YNJD 4QIWA 3GTQA 1UDXA 4JP7A 4H3SA 1EUQA 1G8KA 2JIRA 5EPPA 2B63A 4L48A 2NWAA 1L8FA 3PLXB 4D7ZB 2DMRA 1E5VA 1G8JA 1N10A 1TWHA 1Y4ZA 1B75A 1R9TA 1EXDA 2PNWA 1O0CA 5FTLA 4KLNA 4WFNS 1Y1VA 3D30A 2KQAA 2Y0SA 2E2HA 3X1LB 1YLEA 2VPYA 2CW0D 1OA9A 1H5NA 5FTMA 5DYIA 4JJOA 3IR6A 3CF2A 4C2MA 1I50A 1HD5A 4AONB 3J7ZV 1PQHA 1CZ4A 3CQZA 2PJJA 1SFOA 1VHKA 1O0BA 2G5DA 1E18A 3M3GA 5C18A 2NAPA 4FFTA 2CX8A 2NVXA 1DMSA 2WB1A 5FTKA 5JVHS 3SUMA 1E32A 5C1BA 4P2BA 2R92A 5GADW 5GM9A 1DMRA 3SULA 2AE0X 1IW7D 3X2HA 4KDIA 3GTJA 3GTPA 1BW4A 1GTRA 4AVRA 1QRSA 4AAYA 1ZC1A 2JA7A 5B6CA 2KI8A 1PYQA 3CF5S 2BE5D 5FTNA 2ZJPS 2EEOB 4CRYG 3QQ8A 4JYZA 3TM7B 3FKIA 4IO9S 5IZNA 4V194 1EUYA 3QC8A 2PJHB 4WCES 5T5MD 1KQGA 2JA5A 1K83A 1EU1A 1NYLA 3W2VB 5GAGW 3ML1A 2V3VA 4JCWA 1PYUB 3DLLS 4H4KA 2JIQA 3OUGA 4WFAS 1OA7A 3HU1A 4L69A 5JVGS 1PQEA 1CZ5A 3GTLA 5DM7S 4JXXA 2A69D 5T5ID 4J3CA 2O5JD 3PIPS 4RV0A 1AW8B 4KDLA 3ENGA 4E8BA 4FERA 1FDOA 4ZM7A 3AIIA 1PPYA 1ZYRD 1D6KA 1BW3A 4NOHA 1UHEA 3IR7A 1FDIA 5BNZA 1Z85A 2VUMA 1QTQA 3KW2A 1E61A 4JS7A 2EGVA 3HU2A 1PT0A 4DMRA 2RE8A 2EGWA 2PMZA 2E2IA 3HU3A 2A6ED 2V45A 2ZJQS 4FG4A 1Y5IA 5H4UA 1QCSA 3GTGA 2R7ZA 3SUJA 4AZDA 1VC3B 2A6HD 5GAEW 1TWAA 5FTJA 3DMRA 5GLFA 4JXZA 4KO8A 1SIWA 3GTMA 1Q16A 3QQ7A 4AYBA 1VHYA 3SUKA 2IV2X 4KODA 1TWGA 1UHDA 1TWFA 2A68D 1V6ZA 5HL7S 1QRTA 2ZJRS 2JIMA 2VPXA 2YU9A 4IOAS 3X2OA 4AOKB 2R93A 2HZ7A 1GTSA 1WC2A 2PI8A 1ZJWA 1TWCA 5GLXA 3GTOA 1E60A 3X2MA 4CRZA 5GAHW 3X2GA 1KQFA 3CZBA 4UY88 1SMYD 1OGYA 1Y1WA 3X2PA 2BH0A 3X2NA 1FEUA 2ENGA 1YNND 4WFBS 2JIPA 2YUJA
chains in the Genus database with same CATH topology
1S3SA 2GAEA 2VPZA 4JP6A 1CR5A 1R7RA 3IR5A 1H0HA 1AA6A 1PT1A 4FG2A 4GA5A 3X2LA 2WAQA 2JA6A 2HCZX 2PICA 3O5AA 2G6GA 5GLYA 1WCMA 4CS0A 1WLFA 4GA6A 3GTKA 2C45A 2NVYA 3X2KA 1PQFA 3HKZA 3X2JA 3QWZA 3TIWA 4ENGA 3H0GA 2NYAA 3X2IA 5DYGA 1R27A 2VPWA 2E7ZA 1I3QA 2JIOA 1TMOA 1YNJD 4QIWA 1YNND 3GTQA 4JP7A 1G8KA 2JIRA 5EPPA 2B63A 4L48A 1L8FA 3PLXB 4D7ZB 2DMRA 1E5VA 1G8JA 1N10A 1TWHA 1Y4ZA 1R9TA 2PNWA 5FTLA 4KLNA 1Y1VA 3D30A 2KQAA 2Y0SA 2E2HA 1YLEA 2VPYA 2CW0D 1OA9A 1H5NA 5FTMA 5DYIA 4JJOA 3IR6A 3CF2A 4C2MA 1I50A 1HD5A 4AONB 1PQHA 1CZ4A 3CQZA 2PJJA 1SFOA 2G5DA 1E18A 3M3GA 5C18A 2NAPA 4FFTA 2NVXA 1DMSA 2WB1A 5FTKA 3SUMA 1E32A 5C1BA 2R92A 5GM9A 1DMRA 3SULA 2AE0X 1BW4A 3X2HA 1IW7D 4KDIA 3GTJA 3GTPA 4AVRA 4AAYA 1ZC1A 2JA7A 5B6CA 2KI8A 1PYQA 2BE5D 5FTNA 2EEOB 4CRYG 3QQ8A 3TM7B 3FKIA 3QC8A 2PJHB 5T5MD 1KQGA 2JA5A 1K83A 1EU1A 3ML1A 4JCWA 2V3VA 1PYUB 2JIQA 3OUGA 1OA7A 3HU1A 1PQEA 1CZ5A 3GTLA 2A69D 5T5ID 2O5JD 4RV0A 1AW8B 4KDLA 3ENGA 4FERA 4ZM7A 1FDOA 1PPYA 1ZYRD 1BW3A 4NOHA 1UHEA 3IR7A 1FDIA 2VUMA 1E61A 4JS7A 3HU2A 1PT0A 4DMRA 2PMZA 2E2IA 3HU3A 2A6ED 2V45A 4FG4A 5H4UA 1Y5IA 1QCSA 3GTGA 2R7ZA 3SUJA 4AZDA 1VC3B 2A6HD 1TWAA 5FTJA 3DMRA 5GLFA 4KO8A 1SIWA 3GTMA 1Q16A 3QQ7A 4AYBA 3SUKA 2IV2X 4KODA 1TWGA 1UHDA 1TWFA 2A68D 2JIMA 2VPXA 2YU9A 3X2OA 4AOKB 2R93A 1WC2A 2PI8A 5GLXA 1TWCA 3GTOA 1E60A 3X2MA 4CRZA 3X2GA 1KQFA 3CZBA 1SMYD 1OGYA 1Y1WA 3X2PA 2BH0A 3X2NA 2ENGA 1QDNA 2JIPA 2YUJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GAE A;  4JCW A;  4JP6 A;  1OA9 A;  4FG2 A;  1OA7 A;  4JJO A;  3X2L A;  1HD5 A;  2PJJ A;  2HCZ X;  2G5D A;  2PIC A;  2G6G A;  3M3G A;  5GLY A;  4FFT A;  3SUK A;  3X2K A;  3X2J A;  3SUM A;  4ENG A;  3ENG A;  3X2I A;  4FER A;  4ZM7 A;  5GM9 A;  3SUL A;  2AE0 X;  1BW4 A;  4JP7 A;  3X2H A;  1BW3 A;  4AVR A;  3X2O A;  4L48 A;  1L8F A;  1WC2 A;  2PI8 A;  4JS7 A;  5GLX A;  1N10 A;  3X2M A;  3X2G A;  3CZB A;  2PNW A;  4FG4 A;  2BH0 A;  5H4U A;  3X2N A;  3D30 A;  2ENG A;  3X2P A;  2KQA A;  3SUJ A; 
#chains in the Genus database with same CATH topology
 1S3S A;  2GAE A;  2VPZ A;  4JP6 A;  1CR5 A;  1R7R A;  1QDN A;  1H0H A;  3IR5 A;  1AA6 A;  1PT1 A;  3PIO S;  4FG2 A;  4GA5 A;  3X2L A;  4U67 S;  2Z0Y A;  2WAQ A;  4IOC S;  2JA6 A;  1NXZ A;  2HCZ X;  2PIC A;  3O5A A;  2G6G A;  5DM6 S;  1QRU A;  5GLY A;  4WF9 S;  1WCM A;  4CS0 A;  1WLF A;  4GA6 A;  3GTK A;  3W2W B;  2C45 A;  2RD2 A;  1DFU P;  2NVY A;  3TIW A;  1PQF A;  3HKZ A;  3QWZ A;  3X2K A;  3X2J A;  3H0G A;  4ENG A;  2NYA A;  5DYG A;  3X2I A;  1R27 A;  2VPW A;  2E7Z A;  1I3Q A;  2JIO A;  1TMO A;  1YNJ D;  4QIW A;  3GTQ A;  1UDX A;  4JP7 A;  4H3S A;  1EUQ A;  1G8K A;  2JIR A;  5EPP A;  2B63 A;  4L48 A;  2NWA A;  1L8F A;  3PLX B;  4D7Z B;  2DMR A;  1E5V A;  1G8J A;  1N10 A;  1TWH A;  1Y4Z A;  1B75 A;  1R9T A;  1EXD A;  2PNW A;  1O0C A;  5FTL A;  4KLN A;  4WFN S;  1Y1V A;  3D30 A;  2KQA A;  2Y0S A;  2E2H A;  3X1L B;  1YLE A;  2VPY A;  2CW0 D;  1OA9 A;  1H5N A;  5FTM A;  5DYI A;  4JJO A;  3IR6 A;  3CF2 A;  4C2M A;  1I50 A;  1HD5 A;  4AON B;  3J7Z V;  1PQH A;  1CZ4 A;  3CQZ A;  2PJJ A;  1SFO A;  1VHK A;  1O0B A;  2G5D A;  1E18 A;  3M3G A;  5C18 A;  2NAP A;  4FFT A;  2CX8 A;  2NVX A;  1DMS A;  2WB1 A;  5FTK A;  5JVH S;  3SUM A;  1E32 A;  5C1B A;  4P2B A;  2R92 A;  5GAD W;  5GM9 A;  1DMR A;  3SUL A;  2AE0 X;  1IW7 D;  3X2H A;  4KDI A;  3GTJ A;  3GTP A;  1BW4 A;  1GTR A;  4AVR A;  1QRS A;  4AAY A;  1ZC1 A;  2JA7 A;  5B6C A;  2KI8 A;  1PYQ A;  3CF5 S;  2BE5 D;  5FTN A;  2ZJP S;  2EEO B;  4CRY G;  3QQ8 A;  4JYZ A;  3TM7 B;  3FKI A;  4IO9 S;  5IZN A;  4V19 4;  1EUY A;  3QC8 A;  2PJH B;  4WCE S;  5T5M D;  1KQG A;  2JA5 A;  1K83 A;  1EU1 A;  1NYL A;  3W2V B;  5GAG W;  3ML1 A;  2V3V A;  4JCW A;  1PYU B;  3DLL S;  4H4K A;  2JIQ A;  3OUG A;  4WFA S;  1OA7 A;  3HU1 A;  4L69 A;  5JVG S;  1PQE A;  1CZ5 A;  3GTL A;  5DM7 S;  4JXX A;  2A69 D;  5T5I D;  4J3C A;  2O5J D;  3PIP S;  4RV0 A;  1AW8 B;  4KDL A;  3ENG A;  4E8B A;  4FER A;  1FDO A;  4ZM7 A;  3AII A;  1PPY A;  1ZYR D;  1D6K A;  1BW3 A;  4NOH A;  1UHE A;  3IR7 A;  1FDI A;  5BNZ A;  1Z85 A;  2VUM A;  1QTQ A;  3KW2 A;  1E61 A;  4JS7 A;  2EGV A;  3HU2 A;  1PT0 A;  4DMR A;  2RE8 A;  2EGW A;  2PMZ A;  2E2I A;  3HU3 A;  2A6E D;  2V45 A;  2ZJQ S;  4FG4 A;  1Y5I A;  5H4U A;  1QCS A;  3GTG A;  2R7Z A;  3SUJ A;  4AZD A;  1VC3 B;  2A6H D;  5GAE W;  1TWA A;  5FTJ A;  3DMR A;  5GLF A;  4JXZ A;  4KO8 A;  1SIW A;  3GTM A;  1Q16 A;  3QQ7 A;  4AYB A;  1VHY A;  3SUK A;  2IV2 X;  4KOD A;  1TWG A;  1UHD A;  1TWF A;  2A68 D;  1V6Z A;  5HL7 S;  1QRT A;  2ZJR S;  2JIM A;  2VPX A;  2YU9 A;  4IOA S;  3X2O A;  4AOK B;  2R93 A;  2HZ7 A;  1GTS A;  1WC2 A;  2PI8 A;  1ZJW A;  1TWC A;  5GLX A;  3GTO A;  1E60 A;  3X2M A;  4CRZ A;  5GAH W;  3X2G A;  1KQF A;  3CZB A;  4UY8 8;  1SMY D;  1OGY A;  1Y1W A;  3X2P A;  2BH0 A;  3X2N A;  1FEU A;  2ENG A;  1YNN D;  4WFB S;  2JIP A;  2YUJ A; 
#chains in the Genus database with same CATH homology
 1S3S A;  2GAE A;  2VPZ A;  4JP6 A;  1CR5 A;  1R7R A;  3IR5 A;  1H0H A;  1AA6 A;  1PT1 A;  4FG2 A;  4GA5 A;  3X2L A;  2WAQ A;  2JA6 A;  2HCZ X;  2PIC A;  3O5A A;  2G6G A;  5GLY A;  1WCM A;  4CS0 A;  1WLF A;  4GA6 A;  3GTK A;  2C45 A;  2NVY A;  3X2K A;  1PQF A;  3HKZ A;  3X2J A;  3QWZ A;  3TIW A;  4ENG A;  3H0G A;  2NYA A;  3X2I A;  5DYG A;  1R27 A;  2VPW A;  2E7Z A;  1I3Q A;  2JIO A;  1TMO A;  1YNJ D;  4QIW A;  1YNN D;  3GTQ A;  4JP7 A;  1G8K A;  2JIR A;  5EPP A;  2B63 A;  4L48 A;  1L8F A;  3PLX B;  4D7Z B;  2DMR A;  1E5V A;  1G8J A;  1N10 A;  1TWH A;  1Y4Z A;  1R9T A;  2PNW A;  5FTL A;  4KLN A;  1Y1V A;  3D30 A;  2KQA A;  2Y0S A;  2E2H A;  1YLE A;  2VPY A;  2CW0 D;  1OA9 A;  1H5N A;  5FTM A;  5DYI A;  4JJO A;  3IR6 A;  3CF2 A;  4C2M A;  1I50 A;  1HD5 A;  4AON B;  1PQH A;  1CZ4 A;  3CQZ A;  2PJJ A;  1SFO A;  2G5D A;  1E18 A;  3M3G A;  5C18 A;  2NAP A;  4FFT A;  2NVX A;  1DMS A;  2WB1 A;  5FTK A;  3SUM A;  1E32 A;  5C1B A;  2R92 A;  5GM9 A;  1DMR A;  3SUL A;  2AE0 X;  1BW4 A;  3X2H A;  1IW7 D;  4KDI A;  3GTJ A;  3GTP A;  4AVR A;  4AAY A;  1ZC1 A;  2JA7 A;  5B6C A;  2KI8 A;  1PYQ A;  2BE5 D;  5FTN A;  2EEO B;  4CRY G;  3QQ8 A;  3TM7 B;  3FKI A;  3QC8 A;  2PJH B;  5T5M D;  1KQG A;  2JA5 A;  1K83 A;  1EU1 A;  3ML1 A;  4JCW A;  2V3V A;  1PYU B;  2JIQ A;  3OUG A;  1OA7 A;  3HU1 A;  1PQE A;  1CZ5 A;  3GTL A;  2A69 D;  5T5I D;  2O5J D;  4RV0 A;  1AW8 B;  4KDL A;  3ENG A;  4FER A;  4ZM7 A;  1FDO A;  1PPY A;  1ZYR D;  1BW3 A;  4NOH A;  1UHE A;  3IR7 A;  1FDI A;  2VUM A;  1E61 A;  4JS7 A;  3HU2 A;  1PT0 A;  4DMR A;  2PMZ A;  2E2I A;  3HU3 A;  2A6E D;  2V45 A;  4FG4 A;  5H4U A;  1Y5I A;  1QCS A;  3GTG A;  2R7Z A;  3SUJ A;  4AZD A;  1VC3 B;  2A6H D;  1TWA A;  5FTJ A;  3DMR A;  5GLF A;  4KO8 A;  1SIW A;  3GTM A;  1Q16 A;  3QQ7 A;  4AYB A;  3SUK A;  2IV2 X;  4KOD A;  1TWG A;  1UHD A;  1TWF A;  2A68 D;  2JIM A;  2VPX A;  2YU9 A;  3X2O A;  4AOK B;  2R93 A;  1WC2 A;  2PI8 A;  5GLX A;  1TWC A;  3GTO A;  1E60 A;  3X2M A;  4CRZ A;  3X2G A;  1KQF A;  3CZB A;  1SMY D;  1OGY A;  1Y1W A;  3X2P A;  2BH0 A;  3X2N A;  2ENG A;  1QDN A;  2JIP A;  2YUJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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