2PI8A

Crystal structure of e. coli mlta with bound chitohexaose
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
335
structure length
331
Chain Sequence
SKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLIAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 72
structure length 331
sequence length 335
chains with identical sequence B, C, D
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2pi8A01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2pi8A02
4FERA 4JCWA 4JS7A 2PJJA 5GLXA 4JP7A 3SUJA 3X2PA 3ENGA 4ZM7A 2BH0A 3X2OA 5GLYA 1OA9A 2PI8A 1BW4A 3SUMA 3X2HA 3X2GA 5H4UA 3X2LA 4ENGA 2ENGA 3CZBA 2G6GA 3X2JA 4JJOA 4FG4A 4AVRA 2HCZX 3X2KA 4L48A 3D30A 4JP6A 4FG2A 3SULA 3X2MA 4FFTA 1N10A 1WC2A 3M3GA 1HD5A 2KQAA 2AE0X 1OA7A 3SUKA 3X2NA 1L8FA 2PICA 3X2IA 2G5DA 2PNWA 1BW3A 2GAEA 5GM9A
chains in the Genus database with same CATH superfamily
5GAEW 1PYUB 2PJJA 5GLXA 3SUJA 4WCES 3ENGA 1KQGA 1NXZA 1EU1A 2Y0SA 3TIWA 2NWAA 4L69A 1SFOA 2PI8A 1ZYRD 5T5MD 3SUMA 1Y1WA 3IR6A 2VPWA 5H4UA 3X2LA 2EGWA 4ENGA 5GAGW 3CZBA 3X2JA 2E7ZA 3FKIA 3W2VB 1PQFA 4AVRA 5JVHS 4WF9S 1EUYA 3GTMA 4AOKB 1SIWA 2A69D 2KI8A 3QC8A 2ZJQS 3GTJA 3ML1A 1Y4ZA 1V6ZA 4FFTA 4JXXA 2R7ZA 2C45A 1HD5A 3QQ7A 4IOCS 3X1LB 4AONB 3X2NA 1QTQA 4RV0A 1CZ4A 3X2IA 1WLFA 4J3CA 4CRYG 4C2MA 1H0HA 5GAHW 4CS0A 1OGYA 4JCWA 1PYQA 3X2PA 1DMSA 2JIQA 2A6HD 1QRUA 3X2OA 1VHYA 5EPPA 4H4KA 4P2BA 4WFBS 3H0GA 3GTPA 4KO8A 2V45A 4V194 1QDNA 2CX8A 3O5AA 1E32A 1YNND 4NOHA 2NAPA 1O0CA 5B6CA 3GTGA 5BNZA 5HL7S 5JVGS 3J7ZV 4FG4A 1UHDA 2RD2A 1YLEA 1CR5A 1TWAA 1K83A 2HCZX 2VPYA 3X2KA 1SMYD 1VC3B 2JIOA 3D30A 4L48A 3AIIA 2RE8A 1R9TA 4FG2A 2VPXA 5DYIA 3SULA 2VPZA 3X2MA 5C18A 1N10A 2YU9A 2O5JD 5FTMA 4IO9S 1QRSA 2KQAA 5FTLA 2AE0X 4CRZA 1OA7A 1PQEA 2ZJRS 2ZJPS 2NYAA 1QCSA 2G5DA 4IOAS 2PNWA 1E60A 1CZ5A 5GM9A 1E5VA 1AA6A 2JIMA 3PIOS 1E18A 4JS7A 2B63A 1E61A 1G8KA 4JP7A 1Z85A 2BH0A 2NVXA 5GLYA 1B75A 5IZNA 4GA5A 1OA9A 3HU1A 3GTOA 5GLFA 3X2GA 3X2HA 2JA5A 3W2WB 1Y5IA 1G8JA 2ENGA 2G6GA 1TWGA 2A6ED 3CF2A 1WCMA 4JJOA 4AAYA 4WFAS 1PT1A 4JXZA 2JIPA 4KDIA 5DYGA 5FTKA 4KLNA 3HU3A 1I3QA 2JA6A 2EEOB 4JP6A 2WB1A 1IW7D 1AW8B 1Y1VA 1UHEA 3HKZA 5GADW 2CW0D 1UDXA 1NYLA 4JYZA 4KDLA 5FTNA 2JA7A 1TWHA 1FDIA 3SUKA 4E8BA 3CF5S 2PMZA 1L8FA 1KQFA 1DMRA 2PICA 4KODA 1H5NA 4WFNS 3GTQA 3KW2A 1TWFA 1FDOA 4DMRA 4U67S 4FERA 2E2HA 1PPYA 2YUJA 4ZM7A 1S3SA 1I50A 2R92A 1VHKA 1O0BA 3DMRA 1QRTA 2IV2X 1BW4A 1TWCA 1GTRA 3IR7A 5T5ID 1Q16A 2JIRA 3HU2A 1ZC1A 4QIWA 2EGVA 1R7RA 2DMRA 2R93A 3PIPS 1PQHA 2V3VA 1D6KA 3GTLA 3CQZA 1DFUP 2VUMA 3GTKA 1PT0A 2HZ7A 4GA6A 2WAQA 1EUQA 2A68D 1EXDA 3QQ8A 4UY88 2PJHB 1ZJWA 5DM7S 3DLLS 2BE5D 2Z0YA 1WC2A 3M3GA 1FEUA 2NVYA 5FTJA 4H3SA 1R27A 1GTSA 5C1BA 1TMOA 3QWZA 3TM7B 4AZDA 3OUGA 4AYBA 3PLXB 1YNJD 4D7ZB 1BW3A 2GAEA 3IR5A 5DM6S 2E2IA
chains in the Genus database with same CATH topology
1PYUB 2PJJA 5GLXA 3SUJA 3ENGA 1KQGA 1EU1A 2Y0SA 3TIWA 1SFOA 2PI8A 1ZYRD 5T5MD 3SUMA 1Y1WA 3IR6A 2VPWA 5H4UA 3X2LA 4ENGA 3CZBA 3X2JA 2E7ZA 3FKIA 1PQFA 4AVRA 3GTMA 4AOKB 1SIWA 2A69D 2KI8A 3QC8A 3GTJA 3ML1A 1Y4ZA 4FFTA 2R7ZA 2C45A 1HD5A 3QQ7A 4AONB 3X2NA 4RV0A 1CZ4A 3X2IA 1WLFA 4CRYG 4C2MA 1H0HA 4CS0A 4JCWA 3X2PA 1OGYA 1PYQA 1DMSA 2JIQA 2A6HD 3X2OA 5EPPA 3H0GA 3GTPA 4KO8A 2V45A 1QDNA 3O5AA 1E32A 1YNND 4NOHA 2NAPA 5B6CA 3GTGA 4FG4A 1UHDA 1YLEA 1CR5A 1TWAA 1K83A 2HCZX 3X2KA 2VPYA 1SMYD 1VC3B 4L48A 3D30A 2JIOA 1R9TA 4FG2A 2VPXA 5DYIA 3SULA 3X2MA 2VPZA 5C18A 1N10A 2YU9A 2O5JD 5FTMA 2KQAA 5FTLA 2AE0X 4CRZA 1OA7A 1PQEA 2NYAA 1QCSA 2G5DA 2PNWA 1E60A 1CZ5A 5GM9A 1E5VA 1AA6A 2JIMA 1E18A 4JS7A 2B63A 1G8KA 4JP7A 1E61A 2BH0A 2NVXA 5GLYA 4GA5A 1OA9A 3HU1A 3GTOA 3X2HA 3X2GA 5GLFA 2JA5A 1Y5IA 2ENGA 1G8JA 2G6GA 1TWGA 2A6ED 4JJOA 1WCMA 3CF2A 4AAYA 1PT1A 2JIPA 4KDIA 5DYGA 5FTKA 4KLNA 3HU3A 1I3QA 2JA6A 4JP6A 2EEOB 2WB1A 1IW7D 1AW8B 1Y1VA 1UHEA 3HKZA 2CW0D 4KDLA 5FTNA 2JA7A 1TWHA 1FDIA 3SUKA 2PMZA 1L8FA 1KQFA 2PICA 1DMRA 4KODA 1H5NA 3GTQA 1TWFA 1FDOA 4DMRA 4FERA 2E2HA 1PPYA 2YUJA 4ZM7A 1S3SA 1I50A 2R92A 3DMRA 2IV2X 1BW4A 1TWCA 3IR7A 5T5ID 1Q16A 2JIRA 3HU2A 1ZC1A 4QIWA 1R7RA 2DMRA 2R93A 1PQHA 2V3VA 3GTLA 3CQZA 2VUMA 3GTKA 1PT0A 4GA6A 2WAQA 2A68D 3QQ8A 2PJHB 2BE5D 1WC2A 3M3GA 2NVYA 5FTJA 1R27A 5C1BA 1TMOA 3QWZA 3TM7B 4AZDA 3OUGA 4AYBA 3PLXB 1YNJD 4D7ZB 1BW3A 2GAEA 3IR5A 2E2IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FER A;  4JCW A;  4JS7 A;  2PJJ A;  5GLX A;  4JP7 A;  3SUJ A;  3X2P A;  3ENG A;  4ZM7 A;  2BH0 A;  3X2O A;  5GLY A;  1OA9 A;  2PI8 A;  1BW4 A;  3SUM A;  3X2H A;  3X2G A;  5H4U A;  3X2L A;  4ENG A;  2ENG A;  3CZB A;  2G6G A;  3X2J A;  4JJO A;  4FG4 A;  4AVR A;  2HCZ X;  3X2K A;  4L48 A;  3D30 A;  4JP6 A;  4FG2 A;  3SUL A;  3X2M A;  4FFT A;  1N10 A;  1WC2 A;  3M3G A;  1HD5 A;  2KQA A;  2AE0 X;  1OA7 A;  3SUK A;  3X2N A;  1L8F A;  2PIC A;  3X2I A;  2G5D A;  2PNW A;  1BW3 A;  2GAE A;  5GM9 A; 
#chains in the Genus database with same CATH topology
 5GAE W;  1PYU B;  2PJJ A;  5GLX A;  3SUJ A;  4WCE S;  3ENG A;  1KQG A;  1NXZ A;  1EU1 A;  2Y0S A;  3TIW A;  2NWA A;  4L69 A;  1SFO A;  2PI8 A;  1ZYR D;  5T5M D;  3SUM A;  1Y1W A;  3IR6 A;  2VPW A;  5H4U A;  3X2L A;  2EGW A;  4ENG A;  5GAG W;  3CZB A;  3X2J A;  2E7Z A;  3FKI A;  3W2V B;  1PQF A;  4AVR A;  5JVH S;  4WF9 S;  1EUY A;  3GTM A;  4AOK B;  1SIW A;  2A69 D;  2KI8 A;  3QC8 A;  2ZJQ S;  3GTJ A;  3ML1 A;  1Y4Z A;  1V6Z A;  4FFT A;  4JXX A;  2R7Z A;  2C45 A;  1HD5 A;  3QQ7 A;  4IOC S;  3X1L B;  4AON B;  3X2N A;  1QTQ A;  4RV0 A;  1CZ4 A;  3X2I A;  1WLF A;  4J3C A;  4CRY G;  4C2M A;  1H0H A;  5GAH W;  4CS0 A;  1OGY A;  4JCW A;  1PYQ A;  3X2P A;  1DMS A;  2JIQ A;  2A6H D;  1QRU A;  3X2O A;  1VHY A;  5EPP A;  4H4K A;  4P2B A;  4WFB S;  3H0G A;  3GTP A;  4KO8 A;  2V45 A;  4V19 4;  1QDN A;  2CX8 A;  3O5A A;  1E32 A;  1YNN D;  4NOH A;  2NAP A;  1O0C A;  5B6C A;  3GTG A;  5BNZ A;  5HL7 S;  5JVG S;  3J7Z V;  4FG4 A;  1UHD A;  2RD2 A;  1YLE A;  1CR5 A;  1TWA A;  1K83 A;  2HCZ X;  2VPY A;  3X2K A;  1SMY D;  1VC3 B;  2JIO A;  3D30 A;  4L48 A;  3AII A;  2RE8 A;  1R9T A;  4FG2 A;  2VPX A;  5DYI A;  3SUL A;  2VPZ A;  3X2M A;  5C18 A;  1N10 A;  2YU9 A;  2O5J D;  5FTM A;  4IO9 S;  1QRS A;  2KQA A;  5FTL A;  2AE0 X;  4CRZ A;  1OA7 A;  1PQE A;  2ZJR S;  2ZJP S;  2NYA A;  1QCS A;  2G5D A;  4IOA S;  2PNW A;  1E60 A;  1CZ5 A;  5GM9 A;  1E5V A;  1AA6 A;  2JIM A;  3PIO S;  1E18 A;  4JS7 A;  2B63 A;  1E61 A;  1G8K A;  4JP7 A;  1Z85 A;  2BH0 A;  2NVX A;  5GLY A;  1B75 A;  5IZN A;  4GA5 A;  1OA9 A;  3HU1 A;  3GTO A;  5GLF A;  3X2G A;  3X2H A;  2JA5 A;  3W2W B;  1Y5I A;  1G8J A;  2ENG A;  2G6G A;  1TWG A;  2A6E D;  3CF2 A;  1WCM A;  4JJO A;  4AAY A;  4WFA S;  1PT1 A;  4JXZ A;  2JIP A;  4KDI A;  5DYG A;  5FTK A;  4KLN A;  3HU3 A;  1I3Q A;  2JA6 A;  2EEO B;  4JP6 A;  2WB1 A;  1IW7 D;  1AW8 B;  1Y1V A;  1UHE A;  3HKZ A;  5GAD W;  2CW0 D;  1UDX A;  1NYL A;  4JYZ A;  4KDL A;  5FTN A;  2JA7 A;  1TWH A;  1FDI A;  3SUK A;  4E8B A;  3CF5 S;  2PMZ A;  1L8F A;  1KQF A;  1DMR A;  2PIC A;  4KOD A;  1H5N A;  4WFN S;  3GTQ A;  3KW2 A;  1TWF A;  1FDO A;  4DMR A;  4U67 S;  4FER A;  2E2H A;  1PPY A;  2YUJ A;  4ZM7 A;  1S3S A;  1I50 A;  2R92 A;  1VHK A;  1O0B A;  3DMR A;  1QRT A;  2IV2 X;  1BW4 A;  1TWC A;  1GTR A;  3IR7 A;  5T5I D;  1Q16 A;  2JIR A;  3HU2 A;  1ZC1 A;  4QIW A;  2EGV A;  1R7R A;  2DMR A;  2R93 A;  3PIP S;  1PQH A;  2V3V A;  1D6K A;  3GTL A;  3CQZ A;  1DFU P;  2VUM A;  3GTK A;  1PT0 A;  2HZ7 A;  4GA6 A;  2WAQ A;  1EUQ A;  2A68 D;  1EXD A;  3QQ8 A;  4UY8 8;  2PJH B;  1ZJW A;  5DM7 S;  3DLL S;  2BE5 D;  2Z0Y A;  1WC2 A;  3M3G A;  1FEU A;  2NVY A;  5FTJ A;  4H3S A;  1R27 A;  1GTS A;  5C1B A;  1TMO A;  3QWZ A;  3TM7 B;  4AZD A;  3OUG A;  4AYB A;  3PLX B;  1YNJ D;  4D7Z B;  1BW3 A;  2GAE A;  3IR5 A;  5DM6 S;  2E2I A; 
#chains in the Genus database with same CATH homology
 1PYU B;  2PJJ A;  5GLX A;  3SUJ A;  3ENG A;  1KQG A;  1EU1 A;  2Y0S A;  3TIW A;  1SFO A;  2PI8 A;  1ZYR D;  5T5M D;  3SUM A;  1Y1W A;  3IR6 A;  2VPW A;  5H4U A;  3X2L A;  4ENG A;  3CZB A;  3X2J A;  2E7Z A;  3FKI A;  1PQF A;  4AVR A;  3GTM A;  4AOK B;  1SIW A;  2A69 D;  2KI8 A;  3QC8 A;  3GTJ A;  3ML1 A;  1Y4Z A;  4FFT A;  2R7Z A;  2C45 A;  1HD5 A;  3QQ7 A;  4AON B;  3X2N A;  4RV0 A;  1CZ4 A;  3X2I A;  1WLF A;  4CRY G;  4C2M A;  1H0H A;  4CS0 A;  4JCW A;  3X2P A;  1OGY A;  1PYQ A;  1DMS A;  2JIQ A;  2A6H D;  3X2O A;  5EPP A;  3H0G A;  3GTP A;  4KO8 A;  2V45 A;  1QDN A;  3O5A A;  1E32 A;  1YNN D;  4NOH A;  2NAP A;  5B6C A;  3GTG A;  4FG4 A;  1UHD A;  1YLE A;  1CR5 A;  1TWA A;  1K83 A;  2HCZ X;  3X2K A;  2VPY A;  1SMY D;  1VC3 B;  4L48 A;  3D30 A;  2JIO A;  1R9T A;  4FG2 A;  2VPX A;  5DYI A;  3SUL A;  3X2M A;  2VPZ A;  5C18 A;  1N10 A;  2YU9 A;  2O5J D;  5FTM A;  2KQA A;  5FTL A;  2AE0 X;  4CRZ A;  1OA7 A;  1PQE A;  2NYA A;  1QCS A;  2G5D A;  2PNW A;  1E60 A;  1CZ5 A;  5GM9 A;  1E5V A;  1AA6 A;  2JIM A;  1E18 A;  4JS7 A;  2B63 A;  1G8K A;  4JP7 A;  1E61 A;  2BH0 A;  2NVX A;  5GLY A;  4GA5 A;  1OA9 A;  3HU1 A;  3GTO A;  3X2H A;  3X2G A;  5GLF A;  2JA5 A;  1Y5I A;  2ENG A;  1G8J A;  2G6G A;  1TWG A;  2A6E D;  4JJO A;  1WCM A;  3CF2 A;  4AAY A;  1PT1 A;  2JIP A;  4KDI A;  5DYG A;  5FTK A;  4KLN A;  3HU3 A;  1I3Q A;  2JA6 A;  4JP6 A;  2EEO B;  2WB1 A;  1IW7 D;  1AW8 B;  1Y1V A;  1UHE A;  3HKZ A;  2CW0 D;  4KDL A;  5FTN A;  2JA7 A;  1TWH A;  1FDI A;  3SUK A;  2PMZ A;  1L8F A;  1KQF A;  2PIC A;  1DMR A;  4KOD A;  1H5N A;  3GTQ A;  1TWF A;  1FDO A;  4DMR A;  4FER A;  2E2H A;  1PPY A;  2YUJ A;  4ZM7 A;  1S3S A;  1I50 A;  2R92 A;  3DMR A;  2IV2 X;  1BW4 A;  1TWC A;  3IR7 A;  5T5I D;  1Q16 A;  2JIR A;  3HU2 A;  1ZC1 A;  4QIW A;  1R7R A;  2DMR A;  2R93 A;  1PQH A;  2V3V A;  3GTL A;  3CQZ A;  2VUM A;  3GTK A;  1PT0 A;  4GA6 A;  2WAQ A;  2A68 D;  3QQ8 A;  2PJH B;  2BE5 D;  1WC2 A;  3M3G A;  2NVY A;  5FTJ A;  1R27 A;  5C1B A;  1TMO A;  3QWZ A;  3TM7 B;  4AZD A;  3OUG A;  4AYB A;  3PLX B;  1YNJ D;  4D7Z B;  1BW3 A;  2GAE A;  3IR5 A;  2E2I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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