2PICA

E. coli lytic transglycosylase mlta-d308a in apo-2 form
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
336
structure length
336
Chain Sequence
SSKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLSSRAEIYAGALSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVIIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFAIYQGIGPEAGHRAGWYNHYGRVWVLKTAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords Membrane-bound lytic murein transglycosylase A
total genus 92
structure length 336
sequence length 336
ec nomenclature ec 4.2.2.n1: Peptidoglycan lytic exotransglycosylase.
pdb deposition date 2007-04-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03562 MltA MltA specific insert domain
A PF06725 3D 3D domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.40.10 Mainly Beta Beta Barrel Barwin-like endoglucanases RlpA-like domain 2picA01
2.40.240.50 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Barwin-like endoglucanases 2picA02
1OA9A 4JP6A 2PI8A 2PNWA 3SULA 3M3GA 3D30A 2ENGA 3X2JA 2G5DA 1WC2A 1N10A 4FERA 2BH0A 5GLYA 4FFTA 4FG2A 5GM9A 3X2PA 4AVRA 3SUMA 4L48A 1BW3A 1HD5A 4FG4A 4ENGA 3X2NA 4JP7A 2KQAA 5GLXA 2G6GA 1OA7A 5H4UA 2GAEA 2AE0X 3X2GA 3X2IA 3X2LA 3X2OA 3SUKA 2PICA 2HCZX 4JCWA 4ZM7A 1L8FA 3X2HA 4JS7A 3SUJA 3ENGA 3X2KA 3X2MA 2PJJA 4JJOA 3CZBA 1BW4A
chains in the Genus database with same CATH superfamily
1TWHA 1NXZA 3GTKA 2EEOB 1UDXA 4WFAS 1KQGA 2CW0D 2NVYA 1I50A 1E18A 3D30A 1E60A 1QRSA 4KODA 1QDNA 3X2PA 4AAYA 2C45A 3HU1A 3J7ZV 4AONB 1O0BA 4U67S 1TWAA 3IR7A 4ENGA 2WAQA 1VHKA 2ZJPS 1H5NA 1G8JA 2NYAA 2EGVA 1IW7D 3CF5S 2AE0X 4AOKB 5JVGS 1PYQA 2JA7A 1QTQA 3QC8A 2R93A 4IOAS 2ZJQS 2HCZX 1H0HA 1R27A 3QQ7A 4JCWA 3FKIA 1DMRA 2EGWA 3W2VB 2A6HD 4E8BA 2E2HA 1PQFA 2WB1A 3KW2A 1FEUA 2PMZA 2PJJA 4JJOA 3GTGA 1TWGA 4JP6A 1Y4ZA 3GTOA 3AIIA 2PI8A 5DM7S 4IOCS 1R9TA 1YLEA 1WCMA 2JIQA 4KDIA 1QRUA 5FTKA 2G5DA 1WC2A 3QWZA 2A69D 4C2MA 2BH0A 5GLYA 3DMRA 2JA6A 4L48A 1CZ5A 1KQFA 3HU2A 4FG4A 4L69A 2YUJA 3GTMA 3DLLS 1EXDA 5GLXA 1DFUP 1OA7A 4KDLA 5H4UA 5HL7S 4JXZA 2DMRA 2GAEA 4QIWA 5FTLA 2VUMA 2E2IA 4H4KA 4D7ZB 4WFNS 1OGYA 3X2LA 1G8KA 1QRTA 5GADW 2Y0SA 5B6CA 1PQHA 3QQ8A 4AZDA 5FTNA 3X2HA 4KO8A 1I3QA 1PQEA 1O0CA 3X2KA 3HU3A 5JVHS 4WFBS 1FDIA 2V45A 2ZJRS 5GAEW 5FTJA 4CS0A 3SULA 3IR6A 1V6ZA 3M3GA 1Z85A 5IZNA 4GA6A 3GTJA 2ENGA 3GTPA 1TWCA 5GAHW 2NAPA 1E32A 5GM9A 4AVRA 1Y5IA 2NWAA 1UHEA 2A6ED 3SUMA 2R7ZA 3PLXB 4UY88 1ZYRD 1BW3A 1HD5A 3ML1A 4WF9S 2YU9A 1B75A 2KQAA 3W2WB 2G6GA 4RV0A 1D6KA 1PPYA 2R92A 1GTRA 3X2GA 4CRYG 5T5MD 3O5AA 5BNZA 2V3VA 2KI8A 3OUGA 5DYGA 4V194 1CR5A 2JIPA 4GA5A 4ZM7A 1R7RA 1AA6A 2HZ7A 4JYZA 4JS7A 2E7ZA 3TIWA 5C1BA 1SFOA 3SUJA 3ENGA 1K83A 1NYLA 2Z0YA 1SMYD 3PIPS 2RD2A 2VPZA 5C18A 1ZJWA 1PT0A 3X2MA 4J3CA 5DM6S 1EUQA 5FTMA 1EU1A 1TMOA 1FDOA 1OA9A 3HKZA 2PJHB 4KLNA 4CRZA 1BW4A 2PNWA 4DMRA 1EUYA 1GTSA 5T5ID 2VPWA 1YNND 3X2JA 1E5VA 3GTLA 3H0GA 1N10A 4NOHA 4FERA 2JA5A 3GTQA 1CZ4A 2VPYA 4FFTA 4FG2A 2IV2X 2O5JD 2B63A 2CX8A 3PIOS 1DMSA 1S3SA 3IR5A 1VHYA 3X2NA 4JP7A 1UHDA 3CF2A 1Y1WA 2JIRA 1E61A 1Q16A 3CQZA 1PT1A 1TWFA 1VC3B 3X2IA 2NVXA 1WLFA 1SIWA 4H3SA 2JIMA 3X2OA 1AW8B 3SUKA 4P2BA 2RE8A 2PICA 4IO9S 5GLFA 2JIOA 1PYUB 1L8FA 4AYBA 1QCSA 1ZC1A 2VPXA 1Y1VA 5EPPA 2A68D 4WCES 2BE5D 5GAGW 3X1LB 5DYIA 3CZBA 4JXXA 1YNJD 3TM7B
chains in the Genus database with same CATH topology
1TWHA 3GTKA 2EEOB 1KQGA 2CW0D 2NVYA 1I50A 1E18A 3D30A 1E60A 4KODA 1QDNA 3X2PA 4AAYA 2C45A 3HU1A 4AONB 1TWAA 4ENGA 3IR7A 2WAQA 1H5NA 1G8JA 2NYAA 1IW7D 2AE0X 4AOKB 1PYQA 2JA7A 3QC8A 2R93A 2HCZX 1H0HA 1R27A 4JCWA 3QQ7A 3FKIA 1DMRA 2A6HD 2E2HA 1PQFA 2WB1A 2PMZA 2PJJA 4JJOA 3GTGA 4JP6A 1TWGA 1Y4ZA 3GTOA 2PI8A 1R9TA 1YLEA 1WCMA 2JIQA 4KDIA 5FTKA 2G5DA 1WC2A 3QWZA 2A69D 5DYIA 4C2MA 2BH0A 5GLYA 3DMRA 2JA6A 4L48A 1CZ5A 1KQFA 4FG4A 3HU2A 2YUJA 3GTMA 5GLXA 1OA7A 4KDLA 5H4UA 2DMRA 2GAEA 4QIWA 5FTLA 2VUMA 2E2IA 4D7ZB 1OGYA 3X2LA 1G8KA 2Y0SA 5B6CA 1PQHA 3QQ8A 4AZDA 3X2HA 5FTNA 4KO8A 1I3QA 1PQEA 3X2KA 3HU3A 1FDIA 2V45A 5FTJA 4CS0A 3SULA 3IR6A 3M3GA 4GA6A 3GTJA 2ENGA 3GTPA 1TWCA 2NAPA 1E32A 5GM9A 4AVRA 1Y5IA 1UHEA 3SUMA 2A6ED 2R7ZA 3PLXB 1ZYRD 1BW3A 1HD5A 3ML1A 2YU9A 2KQAA 2G6GA 4RV0A 1PPYA 2R92A 3X2GA 4CRYG 5T5MD 3O5AA 2V3VA 2KI8A 3OUGA 5DYGA 1CR5A 2JIPA 4GA5A 4ZM7A 1R7RA 1AA6A 4JS7A 2E7ZA 3TIWA 5C1BA 1SFOA 3SUJA 3ENGA 1K83A 1SMYD 2VPZA 5C18A 1PT0A 1BW4A 1EU1A 1TMOA 1OA9A 1FDOA 3HKZA 2PJHB 4KLNA 5FTMA 4CRZA 2PNWA 4DMRA 5T5ID 2VPWA 3X2JA 1YNND 1E5VA 3GTLA 3H0GA 1N10A 4NOHA 4FERA 2JA5A 3GTQA 4FFTA 4FG2A 1CZ4A 2VPYA 2IV2X 2O5JD 2B63A 1DMSA 1S3SA 3IR5A 3X2NA 4JP7A 1UHDA 3CF2A 1Y1WA 2JIRA 1E61A 1Q16A 3CQZA 1PT1A 1TWFA 1VC3B 3X2IA 2NVXA 1WLFA 1SIWA 2JIMA 3X2OA 1AW8B 3SUKA 2PICA 5GLFA 2JIOA 1PYUB 1L8FA 4AYBA 1QCSA 1ZC1A 2VPXA 1Y1VA 5EPPA 2A68D 2BE5D 3X2MA 3CZBA 1YNJD 3TM7B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OA9 A;  4JP6 A;  2PI8 A;  2PNW A;  3SUL A;  3M3G A;  3D30 A;  2ENG A;  3X2J A;  2G5D A;  1WC2 A;  1N10 A;  4FER A;  2BH0 A;  5GLY A;  4FFT A;  4FG2 A;  5GM9 A;  3X2P A;  4AVR A;  3SUM A;  4L48 A;  1BW3 A;  1HD5 A;  4FG4 A;  4ENG A;  3X2N A;  4JP7 A;  2KQA A;  5GLX A;  2G6G A;  1OA7 A;  5H4U A;  2GAE A;  2AE0 X;  3X2G A;  3X2I A;  3X2L A;  3X2O A;  3SUK A;  2PIC A;  2HCZ X;  4JCW A;  4ZM7 A;  1L8F A;  3X2H A;  4JS7 A;  3SUJ A;  3ENG A;  3X2K A;  3X2M A;  2PJJ A;  4JJO A;  3CZB A;  1BW4 A; 
#chains in the Genus database with same CATH topology
 1TWH A;  1NXZ A;  3GTK A;  2EEO B;  1UDX A;  4WFA S;  1KQG A;  2CW0 D;  2NVY A;  1I50 A;  1E18 A;  3D30 A;  1E60 A;  1QRS A;  4KOD A;  1QDN A;  3X2P A;  4AAY A;  2C45 A;  3HU1 A;  3J7Z V;  4AON B;  1O0B A;  4U67 S;  1TWA A;  3IR7 A;  4ENG A;  2WAQ A;  1VHK A;  2ZJP S;  1H5N A;  1G8J A;  2NYA A;  2EGV A;  1IW7 D;  3CF5 S;  2AE0 X;  4AOK B;  5JVG S;  1PYQ A;  2JA7 A;  1QTQ A;  3QC8 A;  2R93 A;  4IOA S;  2ZJQ S;  2HCZ X;  1H0H A;  1R27 A;  3QQ7 A;  4JCW A;  3FKI A;  1DMR A;  2EGW A;  3W2V B;  2A6H D;  4E8B A;  2E2H A;  1PQF A;  2WB1 A;  3KW2 A;  1FEU A;  2PMZ A;  2PJJ A;  4JJO A;  3GTG A;  1TWG A;  4JP6 A;  1Y4Z A;  3GTO A;  3AII A;  2PI8 A;  5DM7 S;  4IOC S;  1R9T A;  1YLE A;  1WCM A;  2JIQ A;  4KDI A;  1QRU A;  5FTK A;  2G5D A;  1WC2 A;  3QWZ A;  2A69 D;  4C2M A;  2BH0 A;  5GLY A;  3DMR A;  2JA6 A;  4L48 A;  1CZ5 A;  1KQF A;  3HU2 A;  4FG4 A;  4L69 A;  2YUJ A;  3GTM A;  3DLL S;  1EXD A;  5GLX A;  1DFU P;  1OA7 A;  4KDL A;  5H4U A;  5HL7 S;  4JXZ A;  2DMR A;  2GAE A;  4QIW A;  5FTL A;  2VUM A;  2E2I A;  4H4K A;  4D7Z B;  4WFN S;  1OGY A;  3X2L A;  1G8K A;  1QRT A;  5GAD W;  2Y0S A;  5B6C A;  1PQH A;  3QQ8 A;  4AZD A;  5FTN A;  3X2H A;  4KO8 A;  1I3Q A;  1PQE A;  1O0C A;  3X2K A;  3HU3 A;  5JVH S;  4WFB S;  1FDI A;  2V45 A;  2ZJR S;  5GAE W;  5FTJ A;  4CS0 A;  3SUL A;  3IR6 A;  1V6Z A;  3M3G A;  1Z85 A;  5IZN A;  4GA6 A;  3GTJ A;  2ENG A;  3GTP A;  1TWC A;  5GAH W;  2NAP A;  1E32 A;  5GM9 A;  4AVR A;  1Y5I A;  2NWA A;  1UHE A;  2A6E D;  3SUM A;  2R7Z A;  3PLX B;  4UY8 8;  1ZYR D;  1BW3 A;  1HD5 A;  3ML1 A;  4WF9 S;  2YU9 A;  1B75 A;  2KQA A;  3W2W B;  2G6G A;  4RV0 A;  1D6K A;  1PPY A;  2R92 A;  1GTR A;  3X2G A;  4CRY G;  5T5M D;  3O5A A;  5BNZ A;  2V3V A;  2KI8 A;  3OUG A;  5DYG A;  4V19 4;  1CR5 A;  2JIP A;  4GA5 A;  4ZM7 A;  1R7R A;  1AA6 A;  2HZ7 A;  4JYZ A;  4JS7 A;  2E7Z A;  3TIW A;  5C1B A;  1SFO A;  3SUJ A;  3ENG A;  1K83 A;  1NYL A;  2Z0Y A;  1SMY D;  3PIP S;  2RD2 A;  2VPZ A;  5C18 A;  1ZJW A;  1PT0 A;  3X2M A;  4J3C A;  5DM6 S;  1EUQ A;  5FTM A;  1EU1 A;  1TMO A;  1FDO A;  1OA9 A;  3HKZ A;  2PJH B;  4KLN A;  4CRZ A;  1BW4 A;  2PNW A;  4DMR A;  1EUY A;  1GTS A;  5T5I D;  2VPW A;  1YNN D;  3X2J A;  1E5V A;  3GTL A;  3H0G A;  1N10 A;  4NOH A;  4FER A;  2JA5 A;  3GTQ A;  1CZ4 A;  2VPY A;  4FFT A;  4FG2 A;  2IV2 X;  2O5J D;  2B63 A;  2CX8 A;  3PIO S;  1DMS A;  1S3S A;  3IR5 A;  1VHY A;  3X2N A;  4JP7 A;  1UHD A;  3CF2 A;  1Y1W A;  2JIR A;  1E61 A;  1Q16 A;  3CQZ A;  1PT1 A;  1TWF A;  1VC3 B;  3X2I A;  2NVX A;  1WLF A;  1SIW A;  4H3S A;  2JIM A;  3X2O A;  1AW8 B;  3SUK A;  4P2B A;  2RE8 A;  2PIC A;  4IO9 S;  5GLF A;  2JIO A;  1PYU B;  1L8F A;  4AYB A;  1QCS A;  1ZC1 A;  2VPX A;  1Y1V A;  5EPP A;  2A68 D;  4WCE S;  2BE5 D;  5GAG W;  3X1L B;  5DYI A;  3CZB A;  4JXX A;  1YNJ D;  3TM7 B; 
#chains in the Genus database with same CATH homology
 1TWH A;  3GTK A;  2EEO B;  1KQG A;  2CW0 D;  2NVY A;  1I50 A;  1E18 A;  3D30 A;  1E60 A;  4KOD A;  1QDN A;  3X2P A;  4AAY A;  2C45 A;  3HU1 A;  4AON B;  1TWA A;  4ENG A;  3IR7 A;  2WAQ A;  1H5N A;  1G8J A;  2NYA A;  1IW7 D;  2AE0 X;  4AOK B;  1PYQ A;  2JA7 A;  3QC8 A;  2R93 A;  2HCZ X;  1H0H A;  1R27 A;  4JCW A;  3QQ7 A;  3FKI A;  1DMR A;  2A6H D;  2E2H A;  1PQF A;  2WB1 A;  2PMZ A;  2PJJ A;  4JJO A;  3GTG A;  4JP6 A;  1TWG A;  1Y4Z A;  3GTO A;  2PI8 A;  1R9T A;  1YLE A;  1WCM A;  2JIQ A;  4KDI A;  5FTK A;  2G5D A;  1WC2 A;  3QWZ A;  2A69 D;  5DYI A;  4C2M A;  2BH0 A;  5GLY A;  3DMR A;  2JA6 A;  4L48 A;  1CZ5 A;  1KQF A;  4FG4 A;  3HU2 A;  2YUJ A;  3GTM A;  5GLX A;  1OA7 A;  4KDL A;  5H4U A;  2DMR A;  2GAE A;  4QIW A;  5FTL A;  2VUM A;  2E2I A;  4D7Z B;  1OGY A;  3X2L A;  1G8K A;  2Y0S A;  5B6C A;  1PQH A;  3QQ8 A;  4AZD A;  3X2H A;  5FTN A;  4KO8 A;  1I3Q A;  1PQE A;  3X2K A;  3HU3 A;  1FDI A;  2V45 A;  5FTJ A;  4CS0 A;  3SUL A;  3IR6 A;  3M3G A;  4GA6 A;  3GTJ A;  2ENG A;  3GTP A;  1TWC A;  2NAP A;  1E32 A;  5GM9 A;  4AVR A;  1Y5I A;  1UHE A;  3SUM A;  2A6E D;  2R7Z A;  3PLX B;  1ZYR D;  1BW3 A;  1HD5 A;  3ML1 A;  2YU9 A;  2KQA A;  2G6G A;  4RV0 A;  1PPY A;  2R92 A;  3X2G A;  4CRY G;  5T5M D;  3O5A A;  2V3V A;  2KI8 A;  3OUG A;  5DYG A;  1CR5 A;  2JIP A;  4GA5 A;  4ZM7 A;  1R7R A;  1AA6 A;  4JS7 A;  2E7Z A;  3TIW A;  5C1B A;  1SFO A;  3SUJ A;  3ENG A;  1K83 A;  1SMY D;  2VPZ A;  5C18 A;  1PT0 A;  1BW4 A;  1EU1 A;  1TMO A;  1OA9 A;  1FDO A;  3HKZ A;  2PJH B;  4KLN A;  5FTM A;  4CRZ A;  2PNW A;  4DMR A;  5T5I D;  2VPW A;  3X2J A;  1YNN D;  1E5V A;  3GTL A;  3H0G A;  1N10 A;  4NOH A;  4FER A;  2JA5 A;  3GTQ A;  4FFT A;  4FG2 A;  1CZ4 A;  2VPY A;  2IV2 X;  2O5J D;  2B63 A;  1DMS A;  1S3S A;  3IR5 A;  3X2N A;  4JP7 A;  1UHD A;  3CF2 A;  1Y1W A;  2JIR A;  1E61 A;  1Q16 A;  3CQZ A;  1PT1 A;  1TWF A;  1VC3 B;  3X2I A;  2NVX A;  1WLF A;  1SIW A;  2JIM A;  3X2O A;  1AW8 B;  3SUK A;  2PIC A;  5GLF A;  2JIO A;  1PYU B;  1L8F A;  4AYB A;  1QCS A;  1ZC1 A;  2VPX A;  1Y1V A;  5EPP A;  2A68 D;  2BE5 D;  3X2M A;  3CZB A;  1YNJ D;  3TM7 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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