4ZGAA

Structural basis for inhibition of human autotaxin by four novel compounds
Total Genus 226
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
226
sequence length
804
structure length
740
Chain Sequence
GSCKGRCFELCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGNEENACHCEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGTEERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQACVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Ectonucleotide pyrophosphatase/phosphodiesterase family memb
total genus 226
structure length 740
sequence length 804
ec nomenclature ec 3.1.4.39: Alkylglycerophosphoethanolamine phosphodiesterase.
pdb deposition date 2015-04-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01033 Somatomedin_B Somatomedin B domain
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
A PF01663 Phosphodiest Type I phosphodiesterase / nucleotide pyrophosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4zgaA04
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4zgaA03
4MHXA 1ED8A 3B5QA 5HRTA 3NKNA 3WAWA 1ELXA 1URBA 4UOPA 4UPKA 1ZEFA 5EGHA 1HDHA 5DLWA 2D1GA 2GSOA 4LR9A 4CXSA 4ZG6A 4NWXA 3IGZB 3OT9A 1KH9A 1N2KA 4UPLA 1E1ZP 5L0KA 2GSNA 5LRNA 1KH5A 1KHKA 1ALIA 1ANJA 1KHLA 3A52A 3CMRA 3ED4A 4LRBA 2IUCA 1ANIA 1HQAA 3T01A 3MK0A 2W5SA 3NKOA 4LQYA 5LRMA 1AUKA 1E3CP 2W5QA 4QN0A 1G8TA 3E2DA 4CXKA 3SZYA 5LIAA 1ZEDA 5GKPA 3IGYB 1HJKA 1ELYA 2W8DA 2O3BA 5C66A 3T00A 1KHJA 3BDFA 3NKPA 3M8ZA 2W5TA 4KJDA 5L0EA 4E3YA 2IUCB 4LR7A 1FSUA 3UNYA 1AJBA 2ZKTA 3S5BA 5GKCA 3M8WA 3DPCA 4UPIA 3TX0A 1ALJA 3WAVA 4MIVA 3ISMA 4UORA 1O98A 3MK2A 4KJGA 3SZZA 4FDJA 2W8SA 4GTYA 3M7VA 3DYCA 2QZUA 3NVLA 4LRAA 3NKRA 4GTWA 3UN5A 4UPHA 5IJQA 3Q3QA 4LRDA 1EW2A 5DLVA 1QL0A 5K4PA 1KHNA 2W5RA 2XR9A 2W5WA 3WAXA 4GTZA 4KAYA 3LXQA 1SHNA 1AJCA 5TJ3A 2RH6A 4ZGAA 1EW9A 3IDDA 4LR2A 1Y6VA 4QGOA 4LRFA 3M8YA 4GTXA 4LR8A 2GA3A 1AJDA 4NWJA 2XRGA 5LQQA 4TN0A 2X98A 2XH3A 2GLQA 4B56A 2ANHA 2GSUA 3WAYA 1K7HA 3T02A 1O99A 5KXAA 4LRCA 3TG0A 3TWZA 4A1NA 1AJAA 1KH7A 2IFYA 1ELZA 2VQRA 3BDHA 3MK1A 4FDIA 4QAXA 1SHQA 1EQJA 5EGEA 2G9YA 1Y7AA 4ZG9A 1QAEA 4YR1A 4MY4A 5INHA 5L0BA 1E2SP 3UO0A 1KH4A 3BDGA 1N2LA 1EJJA 1ALHA 4ZG7A 1P49A 4UOOA 3NKQA 5GOVA 3WBHA 3OWVA 2XGRA 1E33P 3UN3A 5GRRA 1ALKA 5AJ9A 3NKMA 4CYSA 1ZEBA 4CYRA 1B8JA 3BDGB 5DLTA 3UN2A 1ZM8A 4N7TA 4CXUA 2W5VA 4LREA 4KM4A 4QH0A 4KAVA 1EI6A 1EW8A 1SMNA 3KD8A 1ED9A 5IJSA 1URAA 2W5XA
chains in the Genus database with same CATH superfamily
4MHXA 1ED8A 3B5QA 5HRTA 3NKNA 3WAWA 1ELXA 1URBA 4UOPA 4UPKA 1ZEFA 5EGHA 1HDHA 5DLWA 2D1GA 2GSOA 4LR9A 4CXSA 4ZG6A 4NWXA 3IGZB 3OT9A 1KH9A 1N2KA 4UPLA 1E1ZP 5L0KA 2GSNA 5LRNA 1KH5A 1KHKA 1ALIA 1ANJA 1KHLA 3A52A 3CMRA 3ED4A 4LRBA 2IUCA 1ANIA 1HQAA 3T01A 3MK0A 2W5SA 3NKOA 4LQYA 5LRMA 1AUKA 1E3CP 2W5QA 4QN0A 1G8TA 3E2DA 4CXKA 3SZYA 5LIAA 1ZEDA 5GKPA 3IGYB 1HJKA 1ELYA 2W8DA 2O3BA 5C66A 3T00A 1KHJA 3BDFA 3NKPA 3M8ZA 2W5TA 4KJDA 5L0EA 4E3YA 2IUCB 4LR7A 1FSUA 3UNYA 1AJBA 2ZKTA 3S5BA 5GKCA 3M8WA 3DPCA 4UPIA 3TX0A 1ALJA 3WAVA 4MIVA 3ISMA 4UORA 1O98A 3MK2A 4KJGA 3SZZA 4FDJA 2W8SA 4GTYA 3M7VA 3DYCA 2QZUA 3NVLA 4LRAA 3NKRA 4GTWA 3UN5A 4UPHA 5IJQA 3Q3QA 4LRDA 1EW2A 5DLVA 1QL0A 5K4PA 1KHNA 2W5RA 2XR9A 2W5WA 3WAXA 4GTZA 4KAYA 3LXQA 1SHNA 1AJCA 5TJ3A 2RH6A 4ZGAA 1EW9A 3IDDA 4LR2A 1Y6VA 4QGOA 4LRFA 3M8YA 4GTXA 4LR8A 2GA3A 1AJDA 4NWJA 2XRGA 5LQQA 4TN0A 2X98A 2XH3A 2GLQA 4B56A 2ANHA 2GSUA 3WAYA 1K7HA 3T02A 1O99A 5KXAA 4LRCA 3TG0A 3TWZA 4A1NA 1AJAA 1KH7A 2IFYA 1ELZA 2VQRA 3BDHA 3MK1A 4FDIA 4QAXA 1SHQA 1EQJA 5EGEA 2G9YA 1Y7AA 4ZG9A 1QAEA 4YR1A 4MY4A 5INHA 5L0BA 1E2SP 3UO0A 1KH4A 3BDGA 1N2LA 1EJJA 1ALHA 4ZG7A 1P49A 4UOOA 3NKQA 5GOVA 3WBHA 3OWVA 2XGRA 1E33P 3UN3A 5GRRA 1ALKA 5AJ9A 3NKMA 4CYSA 1ZEBA 4CYRA 1B8JA 3BDGB 5DLTA 3UN2A 1ZM8A 4N7TA 4CXUA 2W5VA 4LREA 4KM4A 4QH0A 4KAVA 1EI6A 1EW8A 1SMNA 3KD8A 1ED9A 5IJSA 1URAA 2W5XA
chains in the Genus database with same CATH topology
4MHXA 1ED8A 3B5QA 5HRTA 3NKNA 3WAWA 1ELXA 1URBA 4UOPA 4UPKA 1ZEFA 5EGHA 1HDHA 5DLWA 2D1GA 2GSOA 4LR9A 4CXSA 4ZG6A 4NWXA 3IGZB 3OT9A 1KH9A 1N2KA 4UPLA 1E1ZP 5L0KA 2GSNA 5LRNA 1KH5A 1KHKA 1ALIA 1ANJA 1KHLA 3A52A 3CMRA 3ED4A 4LRBA 2IUCA 1ANIA 1HQAA 3T01A 3MK0A 2W5SA 3NKOA 4LQYA 5LRMA 1AUKA 1E3CP 2W5QA 4QN0A 1G8TA 3E2DA 4CXKA 3SZYA 5LIAA 1ZEDA 5GKPA 3IGYB 1HJKA 1ELYA 2W8DA 2O3BA 5C66A 3T00A 1KHJA 3BDFA 3NKPA 3M8ZA 2W5TA 4KJDA 5L0EA 4E3YA 2IUCB 4LR7A 1FSUA 3UNYA 1AJBA 2ZKTA 3S5BA 5GKCA 3M8WA 3DPCA 4UPIA 3TX0A 1ALJA 3WAVA 4MIVA 3ISMA 4UORA 1O98A 3MK2A 4KJGA 3SZZA 4FDJA 2W8SA 4GTYA 3M7VA 3DYCA 2QZUA 3NVLA 4LRAA 3NKRA 4GTWA 3UN5A 4UPHA 5IJQA 3Q3QA 4LRDA 1EW2A 5DLVA 1QL0A 5K4PA 1KHNA 2W5RA 2XR9A 2W5WA 3WAXA 4GTZA 4KAYA 3LXQA 1SHNA 1AJCA 5TJ3A 2RH6A 4ZGAA 1EW9A 3IDDA 4LR2A 1Y6VA 4QGOA 4LRFA 3M8YA 4GTXA 4LR8A 2GA3A 1AJDA 4NWJA 2XRGA 5LQQA 4TN0A 2X98A 2XH3A 2GLQA 4B56A 2ANHA 2GSUA 3WAYA 1K7HA 3T02A 1O99A 5KXAA 4LRCA 3TG0A 3TWZA 4A1NA 1AJAA 1KH7A 2IFYA 1ELZA 2VQRA 3BDHA 3MK1A 4FDIA 4QAXA 1SHQA 1EQJA 5EGEA 2G9YA 1Y7AA 4ZG9A 1QAEA 4YR1A 4MY4A 5INHA 5L0BA 1E2SP 3UO0A 1KH4A 3BDGA 1N2LA 1EJJA 1ALHA 4ZG7A 1P49A 4UOOA 3NKQA 5GOVA 3WBHA 3OWVA 2XGRA 1E33P 3UN3A 5GRRA 1ALKA 5AJ9A 3NKMA 4CYSA 1ZEBA 4CYRA 1B8JA 3BDGB 5DLTA 3UN2A 1ZM8A 4N7TA 4CXUA 2W5VA 4LREA 4KM4A 4QH0A 4KAVA 1EI6A 1EW8A 1SMNA 3KD8A 1ED9A 5IJSA 1URAA 2W5XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MHX A;  1ED8 A;  3B5Q A;  5HRT A;  3NKN A;  3WAW A;  1ELX A;  1URB A;  4UOP A;  4UPK A;  1ZEF A;  5EGH A;  1HDH A;  5DLW A;  2D1G A;  2GSO A;  4LR9 A;  4CXS A;  4ZG6 A;  4NWX A;  3IGZ B;  3OT9 A;  1KH9 A;  1N2K A;  4UPL A;  1E1Z P;  5L0K A;  2GSN A;  5LRN A;  1KH5 A;  1KHK A;  1ALI A;  1ANJ A;  1KHL A;  3A52 A;  3CMR A;  3ED4 A;  4LRB A;  2IUC A;  1ANI A;  1HQA A;  3T01 A;  3MK0 A;  2W5S A;  3NKO A;  4LQY A;  5LRM A;  1AUK A;  1E3C P;  2W5Q A;  4QN0 A;  1G8T A;  3E2D A;  4CXK A;  3SZY A;  5LIA A;  1ZED A;  5GKP A;  3IGY B;  1HJK A;  1ELY A;  2W8D A;  2O3B A;  5C66 A;  3T00 A;  1KHJ A;  3BDF A;  3NKP A;  3M8Z A;  2W5T A;  4KJD A;  5L0E A;  4E3Y A;  2IUC B;  4LR7 A;  1FSU A;  3UNY A;  1AJB A;  2ZKT A;  3S5B A;  5GKC A;  3M8W A;  3DPC A;  4UPI A;  3TX0 A;  1ALJ A;  3WAV A;  4MIV A;  3ISM A;  4UOR A;  1O98 A;  3MK2 A;  4KJG A;  3SZZ A;  4FDJ A;  2W8S A;  4GTY A;  3M7V A;  3DYC A;  2QZU A;  3NVL A;  4LRA A;  3NKR A;  4GTW A;  3UN5 A;  4UPH A;  5IJQ A;  3Q3Q A;  4LRD A;  1EW2 A;  5DLV A;  1QL0 A;  5K4P A;  1KHN A;  2W5R A;  2XR9 A;  2W5W A;  3WAX A;  4GTZ A;  4KAY A;  3LXQ A;  1SHN A;  1AJC A;  5TJ3 A;  2RH6 A;  4ZGA A;  1EW9 A;  3IDD A;  4LR2 A;  1Y6V A;  4QGO A;  4LRF A;  3M8Y A;  4GTX A;  4LR8 A;  2GA3 A;  1AJD A;  4NWJ A;  2XRG A;  5LQQ A;  4TN0 A;  2X98 A;  2XH3 A;  2GLQ A;  4B56 A;  2ANH A;  2GSU A;  3WAY A;  1K7H A;  3T02 A;  1O99 A;  5KXA A;  4LRC A;  3TG0 A;  3TWZ A;  4A1N A;  1AJA A;  1KH7 A;  2IFY A;  1ELZ A;  2VQR A;  3BDH A;  3MK1 A;  4FDI A;  4QAX A;  1SHQ A;  1EQJ A;  5EGE A;  2G9Y A;  1Y7A A;  4ZG9 A;  1QAE A;  4YR1 A;  4MY4 A;  5INH A;  5L0B A;  1E2S P;  3UO0 A;  1KH4 A;  3BDG A;  1N2L A;  1EJJ A;  1ALH A;  4ZG7 A;  1P49 A;  4UOO A;  3NKQ A;  5GOV A;  3WBH A;  3OWV A;  2XGR A;  1E33 P;  3UN3 A;  5GRR A;  1ALK A;  5AJ9 A;  3NKM A;  4CYS A;  1ZEB A;  4CYR A;  1B8J A;  3BDG B;  5DLT A;  3UN2 A;  1ZM8 A;  4N7T A;  4CXU A;  2W5V A;  4LRE A;  4KM4 A;  4QH0 A;  4KAV A;  1EI6 A;  1EW8 A;  1SMN A;  3KD8 A;  1ED9 A;  5IJS A;  1URA A;  2W5X A; 
#chains in the Genus database with same CATH topology
 4MHX A;  1ED8 A;  3B5Q A;  5HRT A;  3NKN A;  3WAW A;  1ELX A;  1URB A;  4UOP A;  4UPK A;  1ZEF A;  5EGH A;  1HDH A;  5DLW A;  2D1G A;  2GSO A;  4LR9 A;  4CXS A;  4ZG6 A;  4NWX A;  3IGZ B;  3OT9 A;  1KH9 A;  1N2K A;  4UPL A;  1E1Z P;  5L0K A;  2GSN A;  5LRN A;  1KH5 A;  1KHK A;  1ALI A;  1ANJ A;  1KHL A;  3A52 A;  3CMR A;  3ED4 A;  4LRB A;  2IUC A;  1ANI A;  1HQA A;  3T01 A;  3MK0 A;  2W5S A;  3NKO A;  4LQY A;  5LRM A;  1AUK A;  1E3C P;  2W5Q A;  4QN0 A;  1G8T A;  3E2D A;  4CXK A;  3SZY A;  5LIA A;  1ZED A;  5GKP A;  3IGY B;  1HJK A;  1ELY A;  2W8D A;  2O3B A;  5C66 A;  3T00 A;  1KHJ A;  3BDF A;  3NKP A;  3M8Z A;  2W5T A;  4KJD A;  5L0E A;  4E3Y A;  2IUC B;  4LR7 A;  1FSU A;  3UNY A;  1AJB A;  2ZKT A;  3S5B A;  5GKC A;  3M8W A;  3DPC A;  4UPI A;  3TX0 A;  1ALJ A;  3WAV A;  4MIV A;  3ISM A;  4UOR A;  1O98 A;  3MK2 A;  4KJG A;  3SZZ A;  4FDJ A;  2W8S A;  4GTY A;  3M7V A;  3DYC A;  2QZU A;  3NVL A;  4LRA A;  3NKR A;  4GTW A;  3UN5 A;  4UPH A;  5IJQ A;  3Q3Q A;  4LRD A;  1EW2 A;  5DLV A;  1QL0 A;  5K4P A;  1KHN A;  2W5R A;  2XR9 A;  2W5W A;  3WAX A;  4GTZ A;  4KAY A;  3LXQ A;  1SHN A;  1AJC A;  5TJ3 A;  2RH6 A;  4ZGA A;  1EW9 A;  3IDD A;  4LR2 A;  1Y6V A;  4QGO A;  4LRF A;  3M8Y A;  4GTX A;  4LR8 A;  2GA3 A;  1AJD A;  4NWJ A;  2XRG A;  5LQQ A;  4TN0 A;  2X98 A;  2XH3 A;  2GLQ A;  4B56 A;  2ANH A;  2GSU A;  3WAY A;  1K7H A;  3T02 A;  1O99 A;  5KXA A;  4LRC A;  3TG0 A;  3TWZ A;  4A1N A;  1AJA A;  1KH7 A;  2IFY A;  1ELZ A;  2VQR A;  3BDH A;  3MK1 A;  4FDI A;  4QAX A;  1SHQ A;  1EQJ A;  5EGE A;  2G9Y A;  1Y7A A;  4ZG9 A;  1QAE A;  4YR1 A;  4MY4 A;  5INH A;  5L0B A;  1E2S P;  3UO0 A;  1KH4 A;  3BDG A;  1N2L A;  1EJJ A;  1ALH A;  4ZG7 A;  1P49 A;  4UOO A;  3NKQ A;  5GOV A;  3WBH A;  3OWV A;  2XGR A;  1E33 P;  3UN3 A;  5GRR A;  1ALK A;  5AJ9 A;  3NKM A;  4CYS A;  1ZEB A;  4CYR A;  1B8J A;  3BDG B;  5DLT A;  3UN2 A;  1ZM8 A;  4N7T A;  4CXU A;  2W5V A;  4LRE A;  4KM4 A;  4QH0 A;  4KAV A;  1EI6 A;  1EW8 A;  1SMN A;  3KD8 A;  1ED9 A;  5IJS A;  1URA A;  2W5X A; 
#chains in the Genus database with same CATH homology
 4MHX A;  1ED8 A;  3B5Q A;  5HRT A;  3NKN A;  3WAW A;  1ELX A;  1URB A;  4UOP A;  4UPK A;  1ZEF A;  5EGH A;  1HDH A;  5DLW A;  2D1G A;  2GSO A;  4LR9 A;  4CXS A;  4ZG6 A;  4NWX A;  3IGZ B;  3OT9 A;  1KH9 A;  1N2K A;  4UPL A;  1E1Z P;  5L0K A;  2GSN A;  5LRN A;  1KH5 A;  1KHK A;  1ALI A;  1ANJ A;  1KHL A;  3A52 A;  3CMR A;  3ED4 A;  4LRB A;  2IUC A;  1ANI A;  1HQA A;  3T01 A;  3MK0 A;  2W5S A;  3NKO A;  4LQY A;  5LRM A;  1AUK A;  1E3C P;  2W5Q A;  4QN0 A;  1G8T A;  3E2D A;  4CXK A;  3SZY A;  5LIA A;  1ZED A;  5GKP A;  3IGY B;  1HJK A;  1ELY A;  2W8D A;  2O3B A;  5C66 A;  3T00 A;  1KHJ A;  3BDF A;  3NKP A;  3M8Z A;  2W5T A;  4KJD A;  5L0E A;  4E3Y A;  2IUC B;  4LR7 A;  1FSU A;  3UNY A;  1AJB A;  2ZKT A;  3S5B A;  5GKC A;  3M8W A;  3DPC A;  4UPI A;  3TX0 A;  1ALJ A;  3WAV A;  4MIV A;  3ISM A;  4UOR A;  1O98 A;  3MK2 A;  4KJG A;  3SZZ A;  4FDJ A;  2W8S A;  4GTY A;  3M7V A;  3DYC A;  2QZU A;  3NVL A;  4LRA A;  3NKR A;  4GTW A;  3UN5 A;  4UPH A;  5IJQ A;  3Q3Q A;  4LRD A;  1EW2 A;  5DLV A;  1QL0 A;  5K4P A;  1KHN A;  2W5R A;  2XR9 A;  2W5W A;  3WAX A;  4GTZ A;  4KAY A;  3LXQ A;  1SHN A;  1AJC A;  5TJ3 A;  2RH6 A;  4ZGA A;  1EW9 A;  3IDD A;  4LR2 A;  1Y6V A;  4QGO A;  4LRF A;  3M8Y A;  4GTX A;  4LR8 A;  2GA3 A;  1AJD A;  4NWJ A;  2XRG A;  5LQQ A;  4TN0 A;  2X98 A;  2XH3 A;  2GLQ A;  4B56 A;  2ANH A;  2GSU A;  3WAY A;  1K7H A;  3T02 A;  1O99 A;  5KXA A;  4LRC A;  3TG0 A;  3TWZ A;  4A1N A;  1AJA A;  1KH7 A;  2IFY A;  1ELZ A;  2VQR A;  3BDH A;  3MK1 A;  4FDI A;  4QAX A;  1SHQ A;  1EQJ A;  5EGE A;  2G9Y A;  1Y7A A;  4ZG9 A;  1QAE A;  4YR1 A;  4MY4 A;  5INH A;  5L0B A;  1E2S P;  3UO0 A;  1KH4 A;  3BDG A;  1N2L A;  1EJJ A;  1ALH A;  4ZG7 A;  1P49 A;  4UOO A;  3NKQ A;  5GOV A;  3WBH A;  3OWV A;  2XGR A;  1E33 P;  3UN3 A;  5GRR A;  1ALK A;  5AJ9 A;  3NKM A;  4CYS A;  1ZEB A;  4CYR A;  1B8J A;  3BDG B;  5DLT A;  3UN2 A;  1ZM8 A;  4N7T A;  4CXU A;  2W5V A;  4LRE A;  4KM4 A;  4QH0 A;  4KAV A;  1EI6 A;  1EW8 A;  1SMN A;  3KD8 A;  1ED9 A;  5IJS A;  1URA A;  2W5X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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