1AUW | Genus

Total Genus 180

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	180
sequence length	447
structure length	447
Chain Sequence	TDPIMEKLNSSIAYDQRLSEVDIQGSMAYAKALEKAGILTKTELEKILSGLEKISEEWSKGVFVVKQSDEDINTANERRLKELIGDIAGKLHTGRSRNDQVVTDLKLFMKNSLSIISTHLLQLIKTLVERAAIEIDVILPGYTHLQKAQPIRWSQFLLSHAVALTRDSERLGEVKKRINVLPLGSGALAGNPLDIDREMLRSELEFASISLNSMDAISERDFVVEFLSFATLLMIHLSKMAEDLIIYSTSEFGFLTDSDAFSTGSSLMPQKKNPDSLELIRSKAGRVFGRLASILMVLKGLPSTYNKDLQEDKEAVFDVVDTLTAVLQVATGVISTLQISKENMEKALTPEMLATDLALYLVRKGVPFRQAHTASGKAVHLAETKGITINKLSLEDLKSISPQFSSDVSQVFNFVNSVEQYTALGGTAKSSVTTQIEQLRELMKKQK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 447 atoms

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447 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Eye lens protein
source organism	Anas platyrhynchos
publication title	Structural comparison of the enzymatically active and inactive forms of delta crystallin and the role of histidine 91. pubmed doi rcsb
molecule keywords	DELTA 2 CRYSTALLIN
total genus	180
structure length	447
sequence length	447
chains with identical sequence	B, C, D
ec nomenclature	ec 4.3.2.1: Argininosuccinate lyase.
pdb deposition date	1997-09-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00206	Lyase_1	Lyase
A	PF14698	ASL_C2	Argininosuccinate lyase C-terminal

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.40.30	Mainly Alpha	Orthogonal Bundle	Ribonucleotide Reductase Protein R1; domain 1	Fumarase/aspartase (C-terminal domain)	1auwA03
1.10.275.10	Mainly Alpha	Orthogonal Bundle	Fumarase C; Chain B, domain 1	Fumarase/aspartase (N-terminal domain)	1auwA01
1.20.200.10	Mainly Alpha	Up-down Bundle	Fumarase C; Chain A, domain 2	Fumarase/aspartase (Central domain)	1auwA02

2O7DA 5HW2A 3C8TA 2O6YA 1I0AA 4ADLA 1C3CA 3UNVA 4BABA 1GK3A 5D6BA 1J3UA 4C5SA 1U16A 1Q5NA 1GK2A 5F91A 1YFEA 3NO9A 1HY0A 1K7WA 2O7BA 3TV2A 2O7EA 1HY1A 4BAAA 2VD6A 1FUQA 3RD8A 2O78A 4V2RA 1FUOA 3OCFA 1TJWA 4NLEA 2OHYA 2PTRA 4V2QA 5EYVA 2PFMA 2HVGA 3GTDA 2NYFA 3R6QA 1T6PA 1B8FA 1TJ7A 1YFMA 1YISA 4FLCA 3BHGA 1JSWA 1FUPA 4ADMA 3R6VA 5F92A 4EEIA 3KDYA 2RJRA 1XWOA 4C5RA 2YIIA 4FFXA 4MX2A 1GKMA 4EFCA 4C6GA 3E04A 1TJUA 3R6YA 1VDKA 1GKJA 1Y2MA 3NZ4A 1FURA 2PTQA 3OCEA 1K62A 4NSLA 1RE5A 1TJVA 3RRPA 3QBPA 2FUSA 2PTSA 4CQ5A 1DCNA 4HGVA 1W27A 5EYTA 2E9FA 1AUWA 2NYNA 2QGAB 2J91A 1KQ7A 1U15A 1C3UA 3GZHA 2O7FA 4APAA 3CZOA 1T6JA 1DOFA 1EB4A 3KDZA 2RJSA 2QVEA 4APBA 4C5UA 2X75A
chains in the Genus database with same CATH superfamily

2O7DA 5HW2A 2VL7A 3CI0K 3C8TA 2FENA 2D28C 1IW7D 2VSFA 2O6YA 1Z4KA 1I0AA 3CRVA 1XMCA 4ADLA 1C3CA 1XMDA 3UNVA 1GK3A 4BABA 5D6BA 1T9HA 1J3UA 1XL7A 2JAOA 4L57A 4C5SA 1U16A 3F4RA 5M0JA 2JAUA 1Q5NA 1GK2A 3F4SA 5F91A 1YFEA 3NO9A 1Q92A 1Z4IA 2FELA 3U13A 1U0LA 4YIKA 1HY0A 1K7WA 2O7BA 2D27A 3TV2A 2O7EA 1HY1A 1Z4JA 4BAAA 2VD6A 1FUQA 3RD8A 2O78A 4A15A 1MH9A 1Q91A 4V2RA 1FUOA 5H8WA 3OCFA 1XL8A 1TJWA 4NLEA 2OHYA 2PTRA 1Z4LA 4V2QA 5EYVA 2PFMA 2HVGA 3GTDA 2NYFA 3R6QA 1T6PA 1B8FA 1TJ7A 1YFMA 1YISA 4FLCA 3BHGA 5M0IA 1JSWA 1FUPA 4ADMA 3R6VA 5F92A 4EEIA 3KDYA 2RJRA 4E88A 1XWOA 3CRW1 4C5RA 2YIIA 4WNLA 4YIHA 4FFXA 3F4TA 4MX2A 3U19A 1GKMA 4EFCA 4C6GA 3E04A 1TJUA 3R6YA 1VDKA 4MWOA 3BWVA 1GKJA 1Y2MA 3NZ4A 1FURA 2PTQA 3OCEA 1K62A 4NSLA 2I7DA 1Z4QA 2RCNA 1RE5A 2JAWA 1Z4PX 1TJVA 3RRPA 3QBPA 2FUSA 4MUMA 4NFLA 2PTSA 4CQ5A 1DCNA 4HGVA 1XLYA 1W27A 5EYTA 2E9FA 1AUWA 2NYNA 2QGAB 4IQJM 2J91A 1KQ7A 1U15A 2JARA 1Z4MA 1C3UA 3GZHA 2O7FA 4APAA 3CZOA 1T6JA 1DOFA 1EB4A 3KDZA 2RJSA 2QVEA 4APBA 4L6CA 4C5UA 4L6AA 2X75A 2YV5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2O7D A;  5HW2 A;  3C8T A;  2O6Y A;  1I0A A;  4ADL A;  1C3C A;  3UNV A;  4BAB A;  1GK3 A;  5D6B A;  1J3U A;  4C5S A;  1U16 A;  1Q5N A;  1GK2 A;  5F91 A;  1YFE A;  3NO9 A;  1HY0 A;  1K7W A;  2O7B A;  3TV2 A;  2O7E A;  1HY1 A;  4BAA A;  2VD6 A;  1FUQ A;  3RD8 A;  2O78 A;  4V2R A;  1FUO A;  3OCF A;  1TJW A;  4NLE A;  2OHY A;  2PTR A;  4V2Q A;  5EYV A;  2PFM A;  2HVG A;  3GTD A;  2NYF A;  3R6Q A;  1T6P A;  1B8F A;  1TJ7 A;  1YFM A;  1YIS A;  4FLC A;  3BHG A;  1JSW A;  1FUP A;  4ADM A;  3R6V A;  5F92 A;  4EEI A;  3KDY A;  2RJR A;  1XWO A;  4C5R A;  2YII A;  4FFX A;  4MX2 A;  1GKM A;  4EFC A;  4C6G A;  3E04 A;  1TJU A;  3R6Y A;  1VDK A;  1GKJ A;  1Y2M A;  3NZ4 A;  1FUR A;  2PTQ A;  3OCE A;  1K62 A;  4NSL A;  1RE5 A;  1TJV A;  3RRP A;  3QBP A;  2FUS A;  2PTS A;  4CQ5 A;  1DCN A;  4HGV A;  1W27 A;  5EYT A;  2E9F A;  1AUW A;  2NYN A;  2QGA B;  2J91 A;  1KQ7 A;  1U15 A;  1C3U A;  3GZH A;  2O7F A;  4APA A;  3CZO A;  1T6J A;  1DOF A;  1EB4 A;  3KDZ A;  2RJS A;  2QVE A;  4APB A;  4C5U A;  2X75 A; 
#chains in the Genus database with same CATH topology
 2O7D A;  5HW2 A;  2VL7 A;  3CI0 K;  3C8T A;  2FEN A;  2D28 C;  1IW7 D;  2VSF A;  2O6Y A;  1Z4K A;  1I0A A;  3CRV A;  1XMC A;  4ADL A;  1C3C A;  1XMD A;  3UNV A;  1GK3 A;  4BAB A;  5D6B A;  1T9H A;  1J3U A;  1XL7 A;  2JAO A;  4L57 A;  4C5S A;  1U16 A;  3F4R A;  5M0J A;  2JAU A;  1Q5N A;  1GK2 A;  3F4S A;  5F91 A;  1YFE A;  3NO9 A;  1Q92 A;  1Z4I A;  2FEL A;  3U13 A;  1U0L A;  4YIK A;  1HY0 A;  1K7W A;  2O7B A;  2D27 A;  3TV2 A;  2O7E A;  1HY1 A;  1Z4J A;  4BAA A;  2VD6 A;  1FUQ A;  3RD8 A;  2O78 A;  4A15 A;  1MH9 A;  1Q91 A;  4V2R A;  1FUO A;  5H8W A;  3OCF A;  1XL8 A;  1TJW A;  4NLE A;  2OHY A;  2PTR A;  1Z4L A;  4V2Q A;  5EYV A;  2PFM A;  2HVG A;  3GTD A;  2NYF A;  3R6Q A;  1T6P A;  1B8F A;  1TJ7 A;  1YFM A;  1YIS A;  4FLC A;  3BHG A;  5M0I A;  1JSW A;  1FUP A;  4ADM A;  3R6V A;  5F92 A;  4EEI A;  3KDY A;  2RJR A;  4E88 A;  1XWO A;  3CRW 1;  4C5R A;  2YII A;  4WNL A;  4YIH A;  4FFX A;  3F4T A;  4MX2 A;  3U19 A;  1GKM A;  4EFC A;  4C6G A;  3E04 A;  1TJU A;  3R6Y A;  1VDK A;  4MWO A;  3BWV A;  1GKJ A;  1Y2M A;  3NZ4 A;  1FUR A;  2PTQ A;  3OCE A;  1K62 A;  4NSL A;  2I7D A;  1Z4Q A;  2RCN A;  1RE5 A;  2JAW A;  1Z4P X;  1TJV A;  3RRP A;  3QBP A;  2FUS A;  4MUM A;  4NFL A;  2PTS A;  4CQ5 A;  1DCN A;  4HGV A;  1XLY A;  1W27 A;  5EYT A;  2E9F A;  1AUW A;  2NYN A;  2QGA B;  4IQJ M;  2J91 A;  1KQ7 A;  1U15 A;  2JAR A;  1Z4M A;  1C3U A;  3GZH A;  2O7F A;  4APA A;  3CZO A;  1T6J A;  1DOF A;  1EB4 A;  3KDZ A;  2RJS A;  2QVE A;  4APB A;  4L6C A;  4C5U A;  4L6A A;  2X75 A;  2YV5 A; 
#chains in the Genus database with same CATH homology
 2O7D A;  5HW2 A;  3C8T A;  2O6Y A;  1I0A A;  4ADL A;  1C3C A;  3UNV A;  4BAB A;  1GK3 A;  5D6B A;  1J3U A;  4C5S A;  1U16 A;  1Q5N A;  1GK2 A;  5F91 A;  1YFE A;  3NO9 A;  1HY0 A;  1K7W A;  2O7B A;  3TV2 A;  2O7E A;  1HY1 A;  4BAA A;  2VD6 A;  1FUQ A;  3RD8 A;  2O78 A;  4V2R A;  1FUO A;  3OCF A;  1TJW A;  4NLE A;  2OHY A;  2PTR A;  4V2Q A;  5EYV A;  2PFM A;  2HVG A;  3GTD A;  2NYF A;  3R6Q A;  1T6P A;  1B8F A;  1TJ7 A;  1YFM A;  1YIS A;  4FLC A;  3BHG A;  1JSW A;  1FUP A;  4ADM A;  3R6V A;  5F92 A;  4EEI A;  3KDY A;  2RJR A;  1XWO A;  4C5R A;  2YII A;  4FFX A;  4MX2 A;  1GKM A;  4EFC A;  4C6G A;  3E04 A;  1TJU A;  3R6Y A;  1VDK A;  1GKJ A;  1Y2M A;  3NZ4 A;  1FUR A;  2PTQ A;  3OCE A;  1K62 A;  4NSL A;  1RE5 A;  1TJV A;  3RRP A;  3QBP A;  2FUS A;  2PTS A;  4CQ5 A;  1DCN A;  4HGV A;  1W27 A;  5EYT A;  2E9F A;  1AUW A;  2NYN A;  2QGA B;  2J91 A;  1KQ7 A;  1U15 A;  1C3U A;  3GZH A;  2O7F A;  4APA A;  3CZO A;  1T6J A;  1DOF A;  1EB4 A;  3KDZ A;  2RJS A;  2QVE A;  4APB A;  4C5U A;  2X75 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1AUWA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations