1FUOA

Fumarase c with bound citrate
Total Genus 175
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
175
sequence length
456
structure length
456
Chain Sequence
VRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQLIPQLKTLTQTLNEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic studies of the catalytic and a second site in fumarase C from Escherichia coli.
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords FUMARASE C
total genus 175
structure length 456
sequence length 456
chains with identical sequence B
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 1996-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 1fuoA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1fuoA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1fuoA02
1C3UA 2PFMA 5EYVA 3E04A 1K62A 2O78A 4FLCA 2NYNA 1Y2MA 1FUPA 1HY0A 3NO9A 1K7WA 4ADMA 3GZHA 3NZ4A 2O7DA 1TJ7A 2RJSA 1I0AA 2E9FA 2VD6A 2O7EA 5D6BA 2FUSA 4APAA 1YISA 3RD8A 3R6VA 2O6YA 3UNVA 1U15A 1RE5A 4EEIA 1YFMA 3R6QA 3CZOA 4C5RA 1TJWA 4CQ5A 3RRPA 4ADLA 2O7FA 2NYFA 4V2QA 1T6JA 3QBPA 1XWOA 5EYTA 2HVGA 5F92A 3BHGA 1HY1A 4C6GA 1EB4A 2PTQA 2J91A 1W27A 2YIIA 2QVEA 4FFXA 5HW2A 2RJRA 1GKMA 4NLEA 4MX2A 4V2RA 1JSWA 1YFEA 3R6YA 3KDYA 1B8FA 4BAAA 2PTSA 1VDKA 2PTRA 4C5SA 3C8TA 1DOFA 1FUOA 1U16A 1T6PA 1Q5NA 5F91A 1J3UA 4NSLA 2OHYA 3OCEA 2O7BA 1DCNA 4EFCA 1TJUA 1GK2A 1FURA 3TV2A 4HGVA 3OCFA 1TJVA 1GKJA 4APBA 1KQ7A 3GTDA 1FUQA 4BABA 3KDZA 2X75A 1C3CA 1AUWA 1GK3A 4C5UA 2QGAB
chains in the Genus database with same CATH superfamily
1C3UA 2PFMA 5EYVA 3E04A 1K62A 2O78A 2FELA 4FLCA 1Z4PX 4YIHA 2NYNA 1Y2MA 1FUPA 1HY0A 3NO9A 1K7WA 4ADMA 4YIKA 5M0JA 2JAOA 3GZHA 3NZ4A 1XLYA 2O7DA 1TJ7A 2RJSA 1I0AA 3U19A 4L6CA 5M0IA 2E9FA 2VD6A 4WNLA 2O7EA 5D6BA 2FUSA 4APAA 3F4RA 1YISA 3F4SA 3RD8A 3R6VA 2O6YA 3UNVA 1U15A 1RE5A 4EEIA 1YFMA 3R6QA 3CZOA 4C5RA 1TJWA 3CRVA 3RRPA 4ADLA 2O7FA 4CQ5A 2NYFA 4NFLA 4V2QA 1T6JA 4L57A 4IQJM 3QBPA 1XL7A 1XWOA 5EYTA 2HVGA 5F92A 2YV5A 3BHGA 4A15A 1Q91A 1HY1A 4C6GA 1EB4A 2PTQA 1XL8A 4L6AA 2J91A 1W27A 2YIIA 1Z4KA 2JAUA 2QVEA 4FFXA 4MUMA 5HW2A 2RJRA 1IW7D 1GKMA 5H8WA 2D28C 1Z4MA 1Q92A 1Z4LA 1Z4IA 2VSFA 4NLEA 3BWVA 4MX2A 2I7DA 4V2RA 1JSWA 1YFEA 3R6YA 3KDYA 2JARA 2D27A 3CI0K 1B8FA 4BAAA 2JAWA 4MWOA 2PTSA 1VDKA 2PTRA 4E88A 4C5SA 1Z4JA 3C8TA 3CRW1 1DOFA 1FUOA 1U16A 1T6PA 1Q5NA 5F91A 1MH9A 2RCNA 1Z4QA 1J3UA 4NSLA 2OHYA 3F4TA 3U13A 3OCEA 2O7BA 1DCNA 4EFCA 1TJUA 1GK2A 2FENA 1U0LA 1FURA 3TV2A 4HGVA 3OCFA 1TJVA 1GKJA 4APBA 1KQ7A 3GTDA 1XMCA 1FUQA 4BABA 3KDZA 2X75A 1C3CA 1AUWA 1XMDA 2VL7A 1GK3A 4C5UA 2QGAB 1T9HA
chains in the Genus database with same CATH topology
1C3UA 2PFMA 5EYVA 3E04A 1K62A 2O78A 4FLCA 2NYNA 1Y2MA 1FUPA 1HY0A 3NO9A 1K7WA 4ADMA 3GZHA 3NZ4A 2O7DA 1TJ7A 2RJSA 1I0AA 2E9FA 2VD6A 2O7EA 5D6BA 2FUSA 4APAA 1YISA 3RD8A 3R6VA 2O6YA 3UNVA 1U15A 1RE5A 4EEIA 1YFMA 3R6QA 3CZOA 4C5RA 1TJWA 4CQ5A 3RRPA 4ADLA 2O7FA 2NYFA 4V2QA 1T6JA 3QBPA 1XWOA 5EYTA 2HVGA 5F92A 3BHGA 1HY1A 4C6GA 1EB4A 2PTQA 2J91A 1W27A 2YIIA 2QVEA 4FFXA 5HW2A 2RJRA 1GKMA 4NLEA 4MX2A 4V2RA 1JSWA 1YFEA 3R6YA 3KDYA 1B8FA 4BAAA 2PTSA 1VDKA 2PTRA 4C5SA 3C8TA 1DOFA 1FUOA 1U16A 1T6PA 1Q5NA 5F91A 1J3UA 4NSLA 2OHYA 3OCEA 2O7BA 1DCNA 4EFCA 1TJUA 1GK2A 1FURA 3TV2A 4HGVA 3OCFA 1TJVA 1GKJA 4APBA 1KQ7A 3GTDA 1FUQA 4BABA 3KDZA 2X75A 1C3CA 1AUWA 1GK3A 4C5UA 2QGAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C3U A;  2PFM A;  5EYV A;  3E04 A;  1K62 A;  2O78 A;  4FLC A;  2NYN A;  1Y2M A;  1FUP A;  1HY0 A;  3NO9 A;  1K7W A;  4ADM A;  3GZH A;  3NZ4 A;  2O7D A;  1TJ7 A;  2RJS A;  1I0A A;  2E9F A;  2VD6 A;  2O7E A;  5D6B A;  2FUS A;  4APA A;  1YIS A;  3RD8 A;  3R6V A;  2O6Y A;  3UNV A;  1U15 A;  1RE5 A;  4EEI A;  1YFM A;  3R6Q A;  3CZO A;  4C5R A;  1TJW A;  4CQ5 A;  3RRP A;  4ADL A;  2O7F A;  2NYF A;  4V2Q A;  1T6J A;  3QBP A;  1XWO A;  5EYT A;  2HVG A;  5F92 A;  3BHG A;  1HY1 A;  4C6G A;  1EB4 A;  2PTQ A;  2J91 A;  1W27 A;  2YII A;  2QVE A;  4FFX A;  5HW2 A;  2RJR A;  1GKM A;  4NLE A;  4MX2 A;  4V2R A;  1JSW A;  1YFE A;  3R6Y A;  3KDY A;  1B8F A;  4BAA A;  2PTS A;  1VDK A;  2PTR A;  4C5S A;  3C8T A;  1DOF A;  1FUO A;  1U16 A;  1T6P A;  1Q5N A;  5F91 A;  1J3U A;  4NSL A;  2OHY A;  3OCE A;  2O7B A;  1DCN A;  4EFC A;  1TJU A;  1GK2 A;  1FUR A;  3TV2 A;  4HGV A;  3OCF A;  1TJV A;  1GKJ A;  4APB A;  1KQ7 A;  3GTD A;  1FUQ A;  4BAB A;  3KDZ A;  2X75 A;  1C3C A;  1AUW A;  1GK3 A;  4C5U A;  2QGA B; 
#chains in the Genus database with same CATH topology
 1C3U A;  2PFM A;  5EYV A;  3E04 A;  1K62 A;  2O78 A;  2FEL A;  4FLC A;  1Z4P X;  4YIH A;  2NYN A;  1Y2M A;  1FUP A;  1HY0 A;  3NO9 A;  1K7W A;  4ADM A;  4YIK A;  5M0J A;  2JAO A;  3GZH A;  3NZ4 A;  1XLY A;  2O7D A;  1TJ7 A;  2RJS A;  1I0A A;  3U19 A;  4L6C A;  5M0I A;  2E9F A;  2VD6 A;  4WNL A;  2O7E A;  5D6B A;  2FUS A;  4APA A;  3F4R A;  1YIS A;  3F4S A;  3RD8 A;  3R6V A;  2O6Y A;  3UNV A;  1U15 A;  1RE5 A;  4EEI A;  1YFM A;  3R6Q A;  3CZO A;  4C5R A;  1TJW A;  3CRV A;  3RRP A;  4ADL A;  2O7F A;  4CQ5 A;  2NYF A;  4NFL A;  4V2Q A;  1T6J A;  4L57 A;  4IQJ M;  3QBP A;  1XL7 A;  1XWO A;  5EYT A;  2HVG A;  5F92 A;  2YV5 A;  3BHG A;  4A15 A;  1Q91 A;  1HY1 A;  4C6G A;  1EB4 A;  2PTQ A;  1XL8 A;  4L6A A;  2J91 A;  1W27 A;  2YII A;  1Z4K A;  2JAU A;  2QVE A;  4FFX A;  4MUM A;  5HW2 A;  2RJR A;  1IW7 D;  1GKM A;  5H8W A;  2D28 C;  1Z4M A;  1Q92 A;  1Z4L A;  1Z4I A;  2VSF A;  4NLE A;  3BWV A;  4MX2 A;  2I7D A;  4V2R A;  1JSW A;  1YFE A;  3R6Y A;  3KDY A;  2JAR A;  2D27 A;  3CI0 K;  1B8F A;  4BAA A;  2JAW A;  4MWO A;  2PTS A;  1VDK A;  2PTR A;  4E88 A;  4C5S A;  1Z4J A;  3C8T A;  3CRW 1;  1DOF A;  1FUO A;  1U16 A;  1T6P A;  1Q5N A;  5F91 A;  1MH9 A;  2RCN A;  1Z4Q A;  1J3U A;  4NSL A;  2OHY A;  3F4T A;  3U13 A;  3OCE A;  2O7B A;  1DCN A;  4EFC A;  1TJU A;  1GK2 A;  2FEN A;  1U0L A;  1FUR A;  3TV2 A;  4HGV A;  3OCF A;  1TJV A;  1GKJ A;  4APB A;  1KQ7 A;  3GTD A;  1XMC A;  1FUQ A;  4BAB A;  3KDZ A;  2X75 A;  1C3C A;  1AUW A;  1XMD A;  2VL7 A;  1GK3 A;  4C5U A;  2QGA B;  1T9H A; 
#chains in the Genus database with same CATH homology
 1C3U A;  2PFM A;  5EYV A;  3E04 A;  1K62 A;  2O78 A;  4FLC A;  2NYN A;  1Y2M A;  1FUP A;  1HY0 A;  3NO9 A;  1K7W A;  4ADM A;  3GZH A;  3NZ4 A;  2O7D A;  1TJ7 A;  2RJS A;  1I0A A;  2E9F A;  2VD6 A;  2O7E A;  5D6B A;  2FUS A;  4APA A;  1YIS A;  3RD8 A;  3R6V A;  2O6Y A;  3UNV A;  1U15 A;  1RE5 A;  4EEI A;  1YFM A;  3R6Q A;  3CZO A;  4C5R A;  1TJW A;  4CQ5 A;  3RRP A;  4ADL A;  2O7F A;  2NYF A;  4V2Q A;  1T6J A;  3QBP A;  1XWO A;  5EYT A;  2HVG A;  5F92 A;  3BHG A;  1HY1 A;  4C6G A;  1EB4 A;  2PTQ A;  2J91 A;  1W27 A;  2YII A;  2QVE A;  4FFX A;  5HW2 A;  2RJR A;  1GKM A;  4NLE A;  4MX2 A;  4V2R A;  1JSW A;  1YFE A;  3R6Y A;  3KDY A;  1B8F A;  4BAA A;  2PTS A;  1VDK A;  2PTR A;  4C5S A;  3C8T A;  1DOF A;  1FUO A;  1U16 A;  1T6P A;  1Q5N A;  5F91 A;  1J3U A;  4NSL A;  2OHY A;  3OCE A;  2O7B A;  1DCN A;  4EFC A;  1TJU A;  1GK2 A;  1FUR A;  3TV2 A;  4HGV A;  3OCF A;  1TJV A;  1GKJ A;  4APB A;  1KQ7 A;  3GTD A;  1FUQ A;  4BAB A;  3KDZ A;  2X75 A;  1C3C A;  1AUW A;  1GK3 A;  4C5U A;  2QGA B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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