2QGA | Genus

Total Genus 181

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	181
sequence length	461
structure length	454
Chain Sequence	EHLKNISPIDGRYKKACGELSAFFSEHALIKHRIIVEVRWLLFLNEEELFFEKVTDHSVEVLNQIATNITDSDIARVKAIEEETNHDVKAVEYFVKEKLKNSKREDLLKIKEYVHYLCTSEDINNVAYATCLKACLNDVVIPCLEKIMLKLKDLAVEYSHVPLLSRTHGQPASSTTFGKEMANFYARIHHHVGVIRRVKVCAKFNGAVGNFNAHKVASKDTDWVNTIGLFLKKHFNLTYSIYCTQIQDHDYICELCDGLARANGTLIDLCVDIWLYISNNLLKLKSSTMPHKVNPIDFENAEGNLHIANAFFKLFSSKLPTSRLQRDLSDSTVLRNIGSSLAYCLIAYKSVLKGLNKIDIDRRNLEEELNQNWSTLAEPIQIVMKRHNYVDAYEELKQFTRGKVIDQKIMQEFIKTKCAFLPQDVVDQLLELTPATYTGYADYLAKNVERLSGE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 454 atoms

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454 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Plasmodium vivax
publication title	Plasmodium vivax adenylosuccinate lyase Pv003765 with AMP bound rcsb
molecule keywords	Adenylosuccinate lyase
total genus	181
structure length	454
sequence length	461
chains with identical sequence	C
ec nomenclature	ec 4.3.2.2: Adenylosuccinate lyase.
pdb deposition date	2007-06-28

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00206	Lyase_1	Lyase
B	PF08328	ASL_C	Adenylosuccinate lyase C-terminal

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.40.30	Mainly Alpha	Orthogonal Bundle	Ribonucleotide Reductase Protein R1; domain 1	Fumarase/aspartase (C-terminal domain)	2qgaB03
1.10.275.10	Mainly Alpha	Orthogonal Bundle	Fumarase C; Chain B, domain 1	Fumarase/aspartase (N-terminal domain)	2qgaB01
1.20.200.10	Mainly Alpha	Up-down Bundle	Fumarase C; Chain A, domain 2	Fumarase/aspartase (Central domain)	2qgaB02

3GZHA 5EYTA 4V2RA 4V2QA 2O7EA 1C3UA 1YFMA 4APAA 3RD8A 5HW2A 3CZOA 1VDKA 1YISA 2RJSA 1GK2A 1T6JA 3C8TA 2PTSA 4MX2A 1KQ7A 5D6BA 1T6PA 3BHGA 1J3UA 4NLEA 4EFCA 3UNVA 1YFEA 1DCNA 1K7WA 1Q5NA 1FUOA 3KDZA 2HVGA 3GTDA 2YIIA 4APBA 2QGAB 4C5RA 1C3CA 3NO9A 1TJVA 5F92A 4BABA 1Y2MA 2QVEA 4FLCA 1TJUA 2OHYA 4ADLA 1FUPA 4C5UA 1U16A 2O6YA 1W27A 2RJRA 1RE5A 2NYFA 3R6YA 2PFMA 3E04A 2O7DA 3RRPA 5F91A 1GKMA 3KDYA 3QBPA 3OCEA 1EB4A 1TJ7A 1AUWA 4HGVA 1FUQA 2J91A 1HY0A 4NSLA 4BAAA 3OCFA 3R6QA 1TJWA 2X75A 1JSWA 1DOFA 1XWOA 2PTQA 1K62A 2NYNA 1FURA 4C6GA 1GK3A 1U15A 2PTRA 3R6VA 1HY1A 2E9FA 1B8FA 4ADMA 3TV2A 2O78A 4CQ5A 4FFXA 1I0AA 5EYVA 2O7FA 1GKJA 2O7BA 4C5SA 2FUSA 4EEIA 3NZ4A 2VD6A
chains in the Genus database with same CATH superfamily

3GZHA 4YIHA 5EYTA 4V2RA 5H8WA 4V2QA 1Z4KA 1C3UA 2O7EA 1YFMA 4APAA 1Z4PX 3RD8A 5HW2A 1Z4IA 3CZOA 1VDKA 1YISA 3U19A 2RJSA 1XMDA 1GK2A 1T6JA 3C8TA 5M0JA 1IW7D 3F4RA 2FELA 4WNLA 2PTSA 4A15A 4L6CA 4MX2A 1KQ7A 5D6BA 1T6PA 2D27A 2JAWA 3BHGA 1J3UA 4NLEA 4EFCA 3CI0K 3UNVA 1YFEA 1DCNA 1K7WA 1Q5NA 1Z4JA 1FUOA 3KDZA 2HVGA 3GTDA 2YIIA 1Z4MA 4APBA 2QGAB 4C5RA 1C3CA 3NO9A 4YIKA 4IQJM 1TJVA 2D28C 2VSFA 4L6AA 4MUMA 1XLYA 5M0IA 5F92A 1U0LA 2JARA 4BABA 1Y2MA 2QVEA 4FLCA 1TJUA 1XL8A 2OHYA 4ADLA 1FUPA 4C5UA 2RCNA 1U16A 3F4SA 2O6YA 1W27A 2RJRA 1RE5A 2NYFA 3R6YA 2FENA 1Q91A 1XL7A 2PFMA 3E04A 1MH9A 2O7DA 3RRPA 1Q92A 5F91A 1GKMA 3KDYA 3QBPA 3CRW1 3OCEA 1EB4A 1TJ7A 1AUWA 4HGVA 1FUQA 3BWVA 4E88A 2J91A 1HY0A 4NSLA 4BAAA 3OCFA 3R6QA 1TJWA 4MWOA 2X75A 3CRVA 3F4TA 1JSWA 1DOFA 1XWOA 2PTQA 1K62A 2NYNA 1FURA 4C6GA 1GK3A 1U15A 2PTRA 3R6VA 1HY1A 2E9FA 1B8FA 4ADMA 4L57A 3TV2A 2JAUA 2O78A 1XMCA 1T9HA 4CQ5A 4FFXA 1I0AA 2JAOA 5EYVA 2O7FA 2VL7A 4NFLA 1GKJA 1Z4QA 3U13A 2O7BA 4C5SA 2I7DA 2FUSA 2YV5A 4EEIA 3NZ4A 1Z4LA 2VD6A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3GZH A;  5EYT A;  4V2R A;  4V2Q A;  2O7E A;  1C3U A;  1YFM A;  4APA A;  3RD8 A;  5HW2 A;  3CZO A;  1VDK A;  1YIS A;  2RJS A;  1GK2 A;  1T6J A;  3C8T A;  2PTS A;  4MX2 A;  1KQ7 A;  5D6B A;  1T6P A;  3BHG A;  1J3U A;  4NLE A;  4EFC A;  3UNV A;  1YFE A;  1DCN A;  1K7W A;  1Q5N A;  1FUO A;  3KDZ A;  2HVG A;  3GTD A;  2YII A;  4APB A;  2QGA B;  4C5R A;  1C3C A;  3NO9 A;  1TJV A;  5F92 A;  4BAB A;  1Y2M A;  2QVE A;  4FLC A;  1TJU A;  2OHY A;  4ADL A;  1FUP A;  4C5U A;  1U16 A;  2O6Y A;  1W27 A;  2RJR A;  1RE5 A;  2NYF A;  3R6Y A;  2PFM A;  3E04 A;  2O7D A;  3RRP A;  5F91 A;  1GKM A;  3KDY A;  3QBP A;  3OCE A;  1EB4 A;  1TJ7 A;  1AUW A;  4HGV A;  1FUQ A;  2J91 A;  1HY0 A;  4NSL A;  4BAA A;  3OCF A;  3R6Q A;  1TJW A;  2X75 A;  1JSW A;  1DOF A;  1XWO A;  2PTQ A;  1K62 A;  2NYN A;  1FUR A;  4C6G A;  1GK3 A;  1U15 A;  2PTR A;  3R6V A;  1HY1 A;  2E9F A;  1B8F A;  4ADM A;  3TV2 A;  2O78 A;  4CQ5 A;  4FFX A;  1I0A A;  5EYV A;  2O7F A;  1GKJ A;  2O7B A;  4C5S A;  2FUS A;  4EEI A;  3NZ4 A;  2VD6 A; 
#chains in the Genus database with same CATH topology
 3GZH A;  4YIH A;  5EYT A;  4V2R A;  5H8W A;  4V2Q A;  1Z4K A;  1C3U A;  2O7E A;  1YFM A;  4APA A;  1Z4P X;  3RD8 A;  5HW2 A;  1Z4I A;  3CZO A;  1VDK A;  1YIS A;  3U19 A;  2RJS A;  1XMD A;  1GK2 A;  1T6J A;  3C8T A;  5M0J A;  1IW7 D;  3F4R A;  2FEL A;  4WNL A;  2PTS A;  4A15 A;  4L6C A;  4MX2 A;  1KQ7 A;  5D6B A;  1T6P A;  2D27 A;  2JAW A;  3BHG A;  1J3U A;  4NLE A;  4EFC A;  3CI0 K;  3UNV A;  1YFE A;  1DCN A;  1K7W A;  1Q5N A;  1Z4J A;  1FUO A;  3KDZ A;  2HVG A;  3GTD A;  2YII A;  1Z4M A;  4APB A;  2QGA B;  4C5R A;  1C3C A;  3NO9 A;  4YIK A;  4IQJ M;  1TJV A;  2D28 C;  2VSF A;  4L6A A;  4MUM A;  1XLY A;  5M0I A;  5F92 A;  1U0L A;  2JAR A;  4BAB A;  1Y2M A;  2QVE A;  4FLC A;  1TJU A;  1XL8 A;  2OHY A;  4ADL A;  1FUP A;  4C5U A;  2RCN A;  1U16 A;  3F4S A;  2O6Y A;  1W27 A;  2RJR A;  1RE5 A;  2NYF A;  3R6Y A;  2FEN A;  1Q91 A;  1XL7 A;  2PFM A;  3E04 A;  1MH9 A;  2O7D A;  3RRP A;  1Q92 A;  5F91 A;  1GKM A;  3KDY A;  3QBP A;  3CRW 1;  3OCE A;  1EB4 A;  1TJ7 A;  1AUW A;  4HGV A;  1FUQ A;  3BWV A;  4E88 A;  2J91 A;  1HY0 A;  4NSL A;  4BAA A;  3OCF A;  3R6Q A;  1TJW A;  4MWO A;  2X75 A;  3CRV A;  3F4T A;  1JSW A;  1DOF A;  1XWO A;  2PTQ A;  1K62 A;  2NYN A;  1FUR A;  4C6G A;  1GK3 A;  1U15 A;  2PTR A;  3R6V A;  1HY1 A;  2E9F A;  1B8F A;  4ADM A;  4L57 A;  3TV2 A;  2JAU A;  2O78 A;  1XMC A;  1T9H A;  4CQ5 A;  4FFX A;  1I0A A;  2JAO A;  5EYV A;  2O7F A;  2VL7 A;  4NFL A;  1GKJ A;  1Z4Q A;  3U13 A;  2O7B A;  4C5S A;  2I7D A;  2FUS A;  2YV5 A;  4EEI A;  3NZ4 A;  1Z4L A;  2VD6 A; 
#chains in the Genus database with same CATH homology
 3GZH A;  5EYT A;  4V2R A;  4V2Q A;  2O7E A;  1C3U A;  1YFM A;  4APA A;  3RD8 A;  5HW2 A;  3CZO A;  1VDK A;  1YIS A;  2RJS A;  1GK2 A;  1T6J A;  3C8T A;  2PTS A;  4MX2 A;  1KQ7 A;  5D6B A;  1T6P A;  3BHG A;  1J3U A;  4NLE A;  4EFC A;  3UNV A;  1YFE A;  1DCN A;  1K7W A;  1Q5N A;  1FUO A;  3KDZ A;  2HVG A;  3GTD A;  2YII A;  4APB A;  2QGA B;  4C5R A;  1C3C A;  3NO9 A;  1TJV A;  5F92 A;  4BAB A;  1Y2M A;  2QVE A;  4FLC A;  1TJU A;  2OHY A;  4ADL A;  1FUP A;  4C5U A;  1U16 A;  2O6Y A;  1W27 A;  2RJR A;  1RE5 A;  2NYF A;  3R6Y A;  2PFM A;  3E04 A;  2O7D A;  3RRP A;  5F91 A;  1GKM A;  3KDY A;  3QBP A;  3OCE A;  1EB4 A;  1TJ7 A;  1AUW A;  4HGV A;  1FUQ A;  2J91 A;  1HY0 A;  4NSL A;  4BAA A;  3OCF A;  3R6Q A;  1TJW A;  2X75 A;  1JSW A;  1DOF A;  1XWO A;  2PTQ A;  1K62 A;  2NYN A;  1FUR A;  4C6G A;  1GK3 A;  1U15 A;  2PTR A;  3R6V A;  1HY1 A;  2E9F A;  1B8F A;  4ADM A;  3TV2 A;  2O78 A;  4CQ5 A;  4FFX A;  1I0A A;  5EYV A;  2O7F A;  1GKJ A;  2O7B A;  4C5S A;  2FUS A;  4EEI A;  3NZ4 A;  2VD6 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2QGAB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations