2ZJPS

Thiopeptide antibiotic nosiheptide bound to the large ribosomal subunit of deinococcus radiodurans
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
pubmed doi rcsb
molecule tags Ribosome/antibiotic
molecule keywords 50S RIBOSOMAL PROTEIN L33
total genus 15
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2008-03-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 2zjpS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 2zjpS02
4WFAS 5DM6S 1QRUA 4WFNS 2ZJQS 2ZJPS 5JVGS 1ZJWA 2ZJRS 1O0BA 1EUQA 5GAGW 3AIIA 4IOCS 3PIOS 1GTSA 4JXXA 1EUYA 1QRSA 2HZ7A 1B75A 3DLLS 4JXZA 1DFUP 4UY88 4JYZA 4IO9S 5HL7S 1D6KA 5BNZA 1QRTA 4P2BA 5DM7S 5IZNA 5GADW 5GAHW 4WFBS 4IOAS 1FEUA 3PIPS 2RE8A 1NYLA 5JVHS 4H3SA 3J7ZV 1GTRA 4WF9S 5GAEW 2RD2A 3CF5S 1O0CA 1QTQA 1EXDA 4U67S 4WCES
chains in the Genus database with same CATH superfamily
4WFAS 2A6HA 2KXYA 5IYBC 1TWGC 3WODA 5TMCA 5C3EC 3S14C 1HQMA 4L69A 2ZJPS 1ZJWA 2A68A 4V194 3PO3C 4JXXA 4J3CA 4ZH4A 4A3MC 2YU9C 3S15C 5C44C 4YFNA 4A3IC 4KMUA 4A3LC 2JA8C 2EGWA 4G7ZA 3GTKC 1DFUP 2R93C 2NVTC 4OIQA 2JA6C 2R7ZC 2G5DA 4JYZA 2EGVA 1IW7A 2NVXC 3S1NC 5HL7S 1D6KA 1Y1VC 4AYBD 3S17C 5GAHW 5GADW 1Z85A 2PMZD 2JA7C 1UDXA 4A3BC 3S16C 3W2WB 4OIPA 3X1LB 5GAEW 3S2HC 1WCMC 2PI8A 4C3JC 3RZOC 4LK1A 3HOVC 3GTGC 4BXXC 2PJJA 5DM6S 4BBSC 4WFNS 2R92C 2ZJQS 1O0BA 1EUQA 4KN7A 3AIIA 4IOCS 3PIOS 1GTSA 2NVYC 2GAEA 3HKZD 4C3IC 4Y52C 2PA8D 1BDFA 1TWAC 2PICA 2HZ7A 1B75A 3DLLS 1Y1WC 2VUMC 1I6HC 1V6ZA 5IP9C 4MQ9A 5TMFA 1SFOC 3GTMC 2Z0YA 5BNZA 4QIWD 5IZNA 5C4JC 4WFBS 3HOXC 3I4MC 3PIPS 4A3JC 3W2VB 4BBRC 4OIRA 3J7ZV 2B63C 2RD2A 3FKIC 2A6EA 1O0CA 4YFXA 4A3DC 2O5JA 3GTPC 5IYCC 2O5IA 4WCES 3KW2A 4LLGA 4BY7C 4Q5SA 1TWFC 5IYDC 5JVGS 1I3QC 2ZJRS 1ZYRA 4KN4A 4A3FC 3HOWC 4XLNA 5D4DA 1QRSA 4OINA 4JK1A 1K83C 2BE5A 3S1QC 1TWHC 2E2JC 2JA5C 4G7HA 4C3HC 3I4NC 4A3EC 4MEXA 2CW0A 3HOUC 2G6GA 3K7AC 4C2MC 4A3KC 4A3CC 4XSZA 3S1RC 2PNWA 4XSXA 2WAQD 1R9TC 3CZBA 4A93C 4IOAS 4P2BA 3GTQC 1FEUA 2A69A 4NOIA 3HOZC 3HOYC 4MEYA 1NYLA 4A3GC 1NXZA 5JVHS 4XLPA 4H4KA 1GTRA 3S2DC 4WF9S 1I6VA 2KQ1A 1EXDA 2Y0SD 4X6AC 3RZDC 3CQZC 1YNNA 4LJZA 5C4XC 1QRUA 2NVQC 3GTOC 4GZYA 2L3UA 5GAGW 3S1MC 4LK0A 3EQLA 1EUYA 2NWAA 4YFKA 2PPBA 1YNJA 4E8BA 2E2IC 4JXZA 3M3YC 2AE0X 5IP7C 3DXJA 5FLMC 4QJVA 4UY88 2CX8A 4OIOA 3H0GC 3GTLC 3PO2C 4IO9S 3GTJC 3M4OC 4Y7NC 4G7OA 1VHYA 1I50C 2E2HC 1QRTA 4BY1C 5DM7S 2WB1D 3LYWA 1SMYA 2RE8A 1TWCC 4YG2A 4H3SA 1VHKA 5HQHA 2L5NA 3CF5S 2KPUA 3H3VD 1QTQA 4Q4ZA 4U67S
chains in the Genus database with same CATH topology
4WFAS 5DM6S 1QRUA 4WFNS 2ZJQS 2ZJPS 5JVGS 1ZJWA 2ZJRS 1O0BA 1EUQA 5GAGW 3AIIA 4IOCS 3PIOS 1GTSA 4JXXA 1EUYA 4V194 1QRSA 2HZ7A 1B75A 3DLLS 4JXZA 1DFUP 4UY88 4JYZA 4IO9S 5HL7S 1D6KA 5BNZA 1QRTA 4P2BA 5DM7S 5IZNA 5GADW 5GAHW 4WFBS 4IOAS 1FEUA 3PIPS 2RE8A 1NYLA 1UDXA 3W2VB 5JVHS 4H3SA 4H4KA 3W2WB 3J7ZV 1GTRA 3X1LB 5GAEW 2RD2A 4WF9S 3CF5S 1O0CA 1QTQA 1EXDA 4U67S 4WCES
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA S;  5DM6 S;  1QRU A;  4WFN S;  2ZJQ S;  2ZJP S;  5JVG S;  1ZJW A;  2ZJR S;  1O0B A;  1EUQ A;  5GAG W;  3AII A;  4IOC S;  3PIO S;  1GTS A;  4JXX A;  1EUY A;  1QRS A;  2HZ7 A;  1B75 A;  3DLL S;  4JXZ A;  1DFU P;  4UY8 8;  4JYZ A;  4IO9 S;  5HL7 S;  1D6K A;  5BNZ A;  1QRT A;  4P2B A;  5DM7 S;  5IZN A;  5GAD W;  5GAH W;  4WFB S;  4IOA S;  1FEU A;  3PIP S;  2RE8 A;  1NYL A;  5JVH S;  4H3S A;  3J7Z V;  1GTR A;  4WF9 S;  5GAE W;  2RD2 A;  3CF5 S;  1O0C A;  1QTQ A;  1EXD A;  4U67 S;  4WCE S; 
#chains in the Genus database with same CATH topology
 4WFA S;  2A6H A;  2KXY A;  5IYB C;  1TWG C;  3WOD A;  5TMC A;  5C3E C;  3S14 C;  1HQM A;  4L69 A;  2ZJP S;  1ZJW A;  2A68 A;  4V19 4;  3PO3 C;  4JXX A;  4J3C A;  4ZH4 A;  4A3M C;  2YU9 C;  3S15 C;  5C44 C;  4YFN A;  4A3I C;  4KMU A;  4A3L C;  2JA8 C;  2EGW A;  4G7Z A;  3GTK C;  1DFU P;  2R93 C;  2NVT C;  4OIQ A;  2JA6 C;  2R7Z C;  2G5D A;  4JYZ A;  2EGV A;  1IW7 A;  2NVX C;  3S1N C;  5HL7 S;  1D6K A;  1Y1V C;  4AYB D;  3S17 C;  5GAH W;  5GAD W;  1Z85 A;  2PMZ D;  2JA7 C;  1UDX A;  4A3B C;  3S16 C;  3W2W B;  4OIP A;  3X1L B;  5GAE W;  3S2H C;  1WCM C;  2PI8 A;  4C3J C;  3RZO C;  4LK1 A;  3HOV C;  3GTG C;  4BXX C;  2PJJ A;  5DM6 S;  4BBS C;  4WFN S;  2R92 C;  2ZJQ S;  1O0B A;  1EUQ A;  4KN7 A;  3AII A;  4IOC S;  3PIO S;  1GTS A;  2NVY C;  2GAE A;  3HKZ D;  4C3I C;  4Y52 C;  2PA8 D;  1BDF A;  1TWA C;  2PIC A;  2HZ7 A;  1B75 A;  3DLL S;  1Y1W C;  2VUM C;  1I6H C;  1V6Z A;  5IP9 C;  4MQ9 A;  5TMF A;  1SFO C;  3GTM C;  2Z0Y A;  5BNZ A;  4QIW D;  5IZN A;  5C4J C;  4WFB S;  3HOX C;  3I4M C;  3PIP S;  4A3J C;  3W2V B;  4BBR C;  4OIR A;  3J7Z V;  2B63 C;  2RD2 A;  3FKI C;  2A6E A;  1O0C A;  4YFX A;  4A3D C;  2O5J A;  3GTP C;  5IYC C;  2O5I A;  4WCE S;  3KW2 A;  4LLG A;  4BY7 C;  4Q5S A;  1TWF C;  5IYD C;  5JVG S;  1I3Q C;  2ZJR S;  1ZYR A;  4KN4 A;  4A3F C;  3HOW C;  4XLN A;  5D4D A;  1QRS A;  4OIN A;  4JK1 A;  1K83 C;  2BE5 A;  3S1Q C;  1TWH C;  2E2J C;  2JA5 C;  4G7H A;  4C3H C;  3I4N C;  4A3E C;  4MEX A;  2CW0 A;  3HOU C;  2G6G A;  3K7A C;  4C2M C;  4A3K C;  4A3C C;  4XSZ A;  3S1R C;  2PNW A;  4XSX A;  2WAQ D;  1R9T C;  3CZB A;  4A93 C;  4IOA S;  4P2B A;  3GTQ C;  1FEU A;  2A69 A;  4NOI A;  3HOZ C;  3HOY C;  4MEY A;  1NYL A;  4A3G C;  1NXZ A;  5JVH S;  4XLP A;  4H4K A;  1GTR A;  3S2D C;  4WF9 S;  1I6V A;  2KQ1 A;  1EXD A;  2Y0S D;  4X6A C;  3RZD C;  3CQZ C;  1YNN A;  4LJZ A;  5C4X C;  1QRU A;  2NVQ C;  3GTO C;  4GZY A;  2L3U A;  5GAG W;  3S1M C;  4LK0 A;  3EQL A;  1EUY A;  2NWA A;  4YFK A;  2PPB A;  1YNJ A;  4E8B A;  2E2I C;  4JXZ A;  3M3Y C;  2AE0 X;  5IP7 C;  3DXJ A;  5FLM C;  4QJV A;  4UY8 8;  2CX8 A;  4OIO A;  3H0G C;  3GTL C;  3PO2 C;  4IO9 S;  3GTJ C;  3M4O C;  4Y7N C;  4G7O A;  1VHY A;  1I50 C;  2E2H C;  1QRT A;  4BY1 C;  5DM7 S;  2WB1 D;  3LYW A;  1SMY A;  2RE8 A;  1TWC C;  4YG2 A;  4H3S A;  1VHK A;  5HQH A;  2L5N A;  3CF5 S;  2KPU A;  3H3V D;  1QTQ A;  4Q4Z A;  4U67 S; 
#chains in the Genus database with same CATH homology
 4WFA S;  5DM6 S;  1QRU A;  4WFN S;  2ZJQ S;  2ZJP S;  5JVG S;  1ZJW A;  2ZJR S;  1O0B A;  1EUQ A;  5GAG W;  3AII A;  4IOC S;  3PIO S;  1GTS A;  4JXX A;  1EUY A;  4V19 4;  1QRS A;  2HZ7 A;  1B75 A;  3DLL S;  4JXZ A;  1DFU P;  4UY8 8;  4JYZ A;  4IO9 S;  5HL7 S;  1D6K A;  5BNZ A;  1QRT A;  4P2B A;  5DM7 S;  5IZN A;  5GAD W;  5GAH W;  4WFB S;  4IOA S;  1FEU A;  3PIP S;  2RE8 A;  1NYL A;  1UDX A;  3W2V B;  5JVH S;  4H3S A;  4H4K A;  3W2W B;  3J7Z V;  1GTR A;  3X1L B;  5GAE W;  2RD2 A;  4WF9 S;  3CF5 S;  1O0C A;  1QTQ A;  1EXD A;  4U67 S;  4WCE S; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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