4XSZA

Crystal structure of cbr 9393 bound to escherichia coli rna polymerase holoenzyme
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
pubmed doi rcsb
source organism Escherichia coli (strain k12)
molecule tags Transcription/antibiotic
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 42
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4xszA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4xszA01
2NVXC 4X6AC 3RZDC 2NVTK 1TWAK 1I6HC 4BY1K 2PMZL 3PO2K 3S1MK 2Y0SL 3GTKK 2O5JA 3GTPC 3S17C 4QIWD 4C3IC 3M4OK 1I6HK 3HOWK 2JA7C 3K7AC 3RZOK 1BDFA 1TWCC 5C44C 3S15C 2O5IA 2VUMK 4OINA 2WAQL 4GZYA 3HOVK 4AYBD 2JA6K 1I6VA 1I3QK 2CW0A 5IP9C 2E2HC 3GTMC 2Y0SD 4C3JC 2JA6C 4A3DC 5M5WK 4MEYA 4G7HA 2E2HK 4A3CK 1HQMA 5C3EC 2BE5A 3S1RK 3GTLK 3CQZC 5TMFA 4A3IK 2JA5K 4A3GC 5IYDK 4OIRA 3H3VL 4BBRK 4OIQA 4A3CC 4LJZA 3GTLC 2R92C 1TWHK 4A3JK 4A3IC 2JA5C 3GTGC 3EQLA 3I4NC 4Q4ZA 2PPBA 2A69A 3H0GK 2YU9K 3I4MK 5M5YK 1TWHC 4YFKA 2B63C 3I4NK 4XSZA 3GTQK 4QJVB 1XPPA 4Y7NK 3S1QK 2NVTC 2NVXK 4A3BK 4X6AK 2NVYC 2A6HA 2R93C 4YFXA 4C3IK 3GTOK 2JA7K 4JK1A 3M4OC 3HKZD 3S17K 4Y52K 1SMYA 3M3YC 3HOYC 4BXXC 3DXJA 4LK0A 4A3MC 1I3QC 4OIPA 1WCMK 4G7ZA 3S2DC 4MEXA 5TMCA 3S14K 4BXXK 4A3DK 4A3MK 2R7ZK 3GTJK 4C3JK 5FLMC 3WODA 1Y1VK 1K83C 2E2IK 4NOIA 2R7ZC 1ZYRA 4BY7C 5FJ8K 4KN7A 4BBSK 3H3VD 1Y1VC 1TWGK 2R92K 5IYBC 4KN4A 3S2HC 4G7OA 4BY7K 4ZH4A 4Q5SA 5C4XC 3GTQC 4QIWL 5IYBK 3GTPK 4A3FC 2B63K 2PA8L 5IYCK 1YNNA 2JA8K 3HOUK 5C4XK 3PO3K 2NVYK 4A3FK 1Y1WK 2A6EA 4Y7NC 1R9TC 3S15K 2R93K 3GTOC 3S1NC 4OIOA 1Y1WC 1SFOC 4C2MK 5C44K 4A93C 4A3LK 2PA8D 5IP7K 3HOYK 5IP9K 3S16C 3M3YK 4YFNA 3HOZK 4A3EC 3HOXC 3S14C 1I50C 1WCMC 1TWFK 4AYBL 3S2DK 3S1RC 4LK1A 3CQZK 4XLNA 1I50K 4A3KK 4BBRC 1TWFC 4MQ9A 5C4JK 4YG2A 2E2JK 1K83K 2YU9C 4A3JC 3I4MC 3S1MC 4A3KC 3GTKC 1TWAC 5C4JC 2E2JC 4BY1C 4XSXA 1YNJA 2PMZD 5M5XK 3S2HK 3RZOC 4LLGA 3HOWC 4A3BC 3K7AK 3HOUC 2VUMC 1TWCK 4KMUA 3FKIK 5IYCC 2JA8C 1R9TK 2WB1D 3PO3C 3HOVC 3GTMK 4Y52C 3HKZL 3FKIC 2NVQK 4C2MC 4A3LC 1SFOK 4XLPA 4A93K 5IP7C 3S1NK 5D4DA 5IYDC 5C3EK 5M3FK 2NVQC 4A3GK 2A68A 4C3HC 4A3EK 3S16K 3HOXK 3GTJC 4QJVA 2E2IC 3H0GC 3HOZC 4C3HK 4BBSC 5FLMK 2WB1L 3GTGK 1IW7A 2WAQD 3PO2C 3RZDK 1TWGC 5M3MK 3S1QC
chains in the Genus database with same CATH superfamily
1ZQ1C 2NVTK 4P5AA 4BY1K 3S1MK 3GTKK 2O5JA 4QIWD 1I6HK 2NVYA 3K7AC 3L4KA 4OINA 5JFEA 5HL8A 4AYBD 2E2HC 3GTMC 4IOAS 4AH6A 4MEYA 4IO9S 5L46A 3S1RK 2BE5A 3CQZC 4A3IK 2JA5K 4A3GC 2B63A 4O2DA 3A8JA 1EFWA 2PPBA 4KB4A 4YFKA 4GTLA 4KM9A 3I4NK 2R92A 4GTEA 4QJVB 3AD9C 4X6AK 2A6HA 4YFXA 4JK1A 3M4OC 3HKZD 3DLLS 5IOQA 1XZQB 1VRQC 4KB2A 4BXXC 3DXJA 1I3QC 3TTGA 3MMLB 4IOCS 2ZJPS 4PABA 4A3DK 3PIOS 3N3YA 3T00A 5FLMC 4KN7A 1Y1VC 2V6SA 3GDZA 3OEPA 3T02A 3GIRA 1F93A 5C4XC 3FHZA 2PA8L 5IYCK 2ZUFA 2JA5A 1TWFA 2RH6A 4WCES 4C2MK 4A3LK 3HOYK 3CAGA 3S16C 1I50C 1WCMC 4XLNA 1TWFC 5C4JK 4YG2A 1K83K 2CFAA 4A3JC 1F7VA 3AD7C 4A3KC 3TFHA 4BY1C 3FOFA 4XSXA 5M5XK 3HOWC 2FQOA 2VUMC 4GTDA 3FKIK 4KMDA 3NUHA 3GTQA 1XZPA 1SFOK 4WFBS 4XLPA 1WSVA 1JVIA 5CJ9A 3T01A 4XCHA 2GSUA 3GTMA 2NVQC 5JVGS 3GEIA 1WOOA 3GTOA 3OREA 4QJVA 4C3HK 3SZYA 2GSNA 3PO2C 3RZDK 1TWGC 4ILDA 5M3MK 2JA6A 2NVXC 2Y0SL 3GTPC 3AD8C 1DCPA 4C3IC 1KQ4A 3HOWK 4M1XA 3RZOK 3GTKA 1O2AA 3HOVK 1I3QK 5IP9C 4KAWX 4U67S 2Y0SD 1J6WA 2L3UA 2JA6C 4A3DC 2XCRB 5C3EC 3GTLK 5IYDK 1WOSA 4OIRA 4OIQA 4LJZA 1EH1A 1TWHK 2ZUEA 3I4NC 3H0GK 4Q4ZA 3I4MK 4GTCA 5M5YK 2B63C 2GAGC 3A8KA 1IL2A 2NVTC 1EQRA 4C3IK 3GTOK 1J6XA 3HOYC 3PIPS 1DD5A 5EGHA 2ZFZA 4LK0A 4P9SA 3BP8C 1PJ7A 1WIHA 4PAAA 3SZZA 5TMCA 1PJ6A 1TWCA 2W7VA 4C3JK 1Y1VK 3BP3A 1F9NA 5IOTA 4NOIA 1ZYRA 4BBSK 1JOEA 5IYBC 4KN4A 3S2HC 4BY7K 1ZBSA 4ZH4A 2V6TA 4QIWL 4GTFA 5IORA 3PO3K 1Y1WA 1XZQA 1UV7A 1O25A 2R93K 4GTAA 5C44K 4RMFA 1SFOC 2PA8D 5EGEA 3JSTA 3M3YK 4G0UA 1B4AA 1WSRA 1TWFK 4AYBL 3S2DK 5DM6S 3L4JA 3GSIA 2R7ZA 1ZXOA 3TFJA 4BBRC 1WCMA 3I4MC 1SFOA 2E2JC 1YNJA 4LLGA 4A3BC 3HOUC 2JA8C 3S0XA 3OPFA 3N0BA 3HOVC 1DCHA 3GTMK 4Y52C 2NVQK 1ZVUA 1IE0A 4KM8A 3S1NK 3H0GA 5M3FK 4A3GK 1R9TA 2A68A 1BJTA 2P8TA 2JA7A 3HOXK 3GTJC 2WB1L 5HL7S 3GEEA 1J98A 1V5VA 3Q3QA 1I6HC 4G0WA 2XCOA 3S17C 2ZJQS 1O28A 2JA7C 4BKWA 5C44C 3S15C 2O5IA 3GTPA 2WAQL 4GZYA 2JA6K 1I6VA 1O26A 5M5WK 2FQTA 3LAJA 4G7HA 3GEHA 4FM9A 3H3VL 4BBRK 1VLOA 4A3CC 4J3NA 4A3JK 4A3IC 2JA5C 3GTGC 3EQLA 4WILA 2A69A 3G4AA 2YU9K 3GTQK 3ERED 3S1QK 4Y7NK 1F7UA 1PJ5A 2NVXK 4A3BK 3N0CA 1WQGA 2JA7K 4DDQA 1SMYA 1WOPA 1DCOA 2L5NA 4OIPA 1K83A 2KPUA 3S14K 4BXXK 2V6UA 4A3MK 3GTJK 3WODA 3TFIA 2E2IK 3HXAA 2R7ZC 5FJ8K 3H3VD 1HI9A 1TWGK 2R92K 5JVOA 5DM7S 1USMA 4G0VA 4LOWA 4WFNS 4Q5SA 1C0AA 3GTQC 3GTPK 3A8IA 2B63K 3HOUK 1YNNA 2GAHC 3V4GA 5C4XK 4KMHA 2NVYK 1EI6A 4A3FK 3GTOC 1Y1WC 2CFAB 4KC6A 2JH3A 1TWGA 1RU0A 3HOZK 1XXCA 3HOXC 3S14C 5CHPA 4LK1A 3GTJA 1I50K 4A3KK 2E2JK 2YU9C 3S1MC 4BLBA 4KASA 3GTKC 1INNA 2PMZD 3RZOC 3CF5S 3LYWA 1Y1VA 1TWCK 4KMUA 5IYCC 1R9TK 3PO3C 3ADAC 2XCQA 3HKZL 3FKIC 5JVHS 1WQFA 4GTBA 2YU9A 2D6FC 5IYDC 5C3EK 4C3HC 4A3EK 3S16K 4KMAA 1O24A 1XXBA 3H0GC 1WQHA 5FLMK 4BBSC 1IQ0A 2ZJRS 1IW7A 2WAQD 3GTGK 4GT9A 4X6AC 3RZDC 3PO2K 1TWAK 4FZBA 2PMZL 1L0WA 1BS2A 4GFQA 1XXAA 3M4OK 3GTLA 3LAPA 1BDFA 2GSOA 2E2HA 1TWCC 3AQPA 2VUMK 2EBBA 2CW0A 1VJEA 4WJ3M 1O2BA 4C3JC 2VUMA 2R93A 2RGRA 2E2HK 4A3CK 1HQMA 5E68A 5TMFA 3G4CA 3GTLC 2R92C 3VA7A 4KARA 1TWHC 4XSZA 3GTGA 1XPPA 2NVYC 3FOEA 2R93C 3AQOA 2PHCB 3S17K 4KDDA 1O27A 4Y52K 3IPJA 3M3YC 4WFAS 2Y3PA 4A3MC 1J6VA 1WCMK 4G7ZA 3S2DC 1TWHA 4MEXA 2R7ZK 3CQZA 1K83C 4BY7C 2KQ1A 4P5BA 4G7OA 2P5MA 1USOA 1FEUA 5IYBK 1ISEA 4A3FC 1IS1A 2JA8K 1IBAA 1JQWA 1Y1WK 2A6EA 4Y7NC 1R9TC 4LR2A 3BUEA 3S15K 3S1NC 4OIOA 4BLAA 1TWAA 4A93C 4C45A 5IP7K 1I3QA 5IP9K 1O29A 4YFNA 1XZPB 4A3EC 4LQYA 3S1RC 3CQZK 1O2FB 5IOSA 2KWAA 3AH5A 2KXYA 4MQ9A 1EK8A 1TWAC 5C4JC 1G51A 1VGXA 1WORA 4KATA 3S2HK 4WJ4A 2E2IA 1X31C 1YX2A 1B4BA 3K7AK 1VH2A 2WB1D 1BGWA 1GE9A 4C2MC 4A3LC 4A93K 5IP7C 5D4DA 1AB4A 3LPXA 5HQHA 1I50A 3FKIA 2E2IC 3HOZC 2NVXA 5TJ3A 4WF9S 3QX3A 1YCLA 3S1QC
chains in the Genus database with same CATH topology
2NVXC 4X6AC 3RZDC 2NVTK 1TWAK 1I6HC 4BY1K 2PMZL 3PO2K 3S1MK 2Y0SL 3GTKK 2O5JA 3GTPC 3S17C 4QIWD 4C3IC 3M4OK 1I6HK 3HOWK 2JA7C 3K7AC 3RZOK 1BDFA 1TWCC 5C44C 3S15C 2O5IA 2VUMK 4OINA 2WAQL 4GZYA 3HOVK 4AYBD 2JA6K 1I6VA 1I3QK 2CW0A 5IP9C 2E2HC 3GTMC 2Y0SD 4C3JC 2JA6C 4A3DC 5M5WK 4MEYA 4G7HA 2E2HK 4A3CK 1HQMA 5C3EC 2BE5A 3S1RK 3GTLK 3CQZC 5TMFA 4A3IK 2JA5K 4A3GC 5IYDK 4OIRA 3H3VL 4BBRK 4OIQA 4A3CC 4LJZA 3GTLC 2R92C 1TWHK 4A3JK 4A3IC 2JA5C 3GTGC 3EQLA 3I4NC 4Q4ZA 2PPBA 2A69A 3H0GK 2YU9K 3I4MK 5M5YK 1TWHC 4YFKA 2B63C 3I4NK 4XSZA 3GTQK 4QJVB 1XPPA 4Y7NK 3S1QK 2NVTC 2NVXK 4A3BK 4X6AK 2NVYC 2A6HA 2R93C 4YFXA 4C3IK 3GTOK 2JA7K 4JK1A 3M4OC 3HKZD 3S17K 4Y52K 1SMYA 3M3YC 3HOYC 4BXXC 3DXJA 4LK0A 4A3MC 1I3QC 4OIPA 1WCMK 4G7ZA 3S2DC 4MEXA 5TMCA 3S14K 4BXXK 4A3DK 4A3MK 2R7ZK 3GTJK 4C3JK 5FLMC 3WODA 1Y1VK 1K83C 2E2IK 4NOIA 2R7ZC 1ZYRA 4BY7C 5FJ8K 4KN7A 4BBSK 3H3VD 1Y1VC 1TWGK 2R92K 5IYBC 4KN4A 3S2HC 4G7OA 4BY7K 4ZH4A 4Q5SA 5C4XC 3GTQC 4QIWL 5IYBK 3GTPK 4A3FC 2B63K 2PA8L 5IYCK 1YNNA 2JA8K 3HOUK 5C4XK 3PO3K 2NVYK 4A3FK 1Y1WK 2A6EA 4Y7NC 1R9TC 3S15K 2R93K 3GTOC 3S1NC 4OIOA 1Y1WC 1SFOC 4C2MK 5C44K 4A93C 4A3LK 2PA8D 5IP7K 3HOYK 5IP9K 3S16C 3M3YK 4YFNA 3HOZK 4A3EC 3HOXC 3S14C 1I50C 1WCMC 1TWFK 4AYBL 3S2DK 3S1RC 4LK1A 3CQZK 4XLNA 1I50K 4A3KK 4BBRC 1TWFC 4MQ9A 5C4JK 4YG2A 2E2JK 1K83K 2YU9C 4A3JC 3I4MC 3S1MC 4A3KC 3GTKC 1TWAC 5C4JC 2E2JC 4BY1C 4XSXA 1YNJA 2PMZD 5M5XK 3S2HK 3RZOC 4LLGA 3HOWC 4A3BC 3K7AK 3HOUC 2VUMC 1TWCK 4KMUA 3FKIK 5IYCC 2JA8C 1R9TK 2WB1D 3PO3C 3HOVC 3GTMK 4Y52C 3HKZL 3FKIC 2NVQK 4C2MC 4A3LC 1SFOK 4XLPA 4A93K 5IP7C 3S1NK 5D4DA 5IYDC 5C3EK 5M3FK 2NVQC 4A3GK 2A68A 4C3HC 4A3EK 3S16K 3HOXK 3GTJC 4QJVA 2E2IC 3H0GC 3HOZC 4C3HK 4BBSC 5FLMK 2WB1L 3GTGK 1IW7A 2WAQD 3PO2C 3RZDK 1TWGC 5M3MK 3S1QC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVX C;  4X6A C;  3RZD C;  2NVT K;  1TWA K;  1I6H C;  4BY1 K;  2PMZ L;  3PO2 K;  3S1M K;  2Y0S L;  3GTK K;  2O5J A;  3GTP C;  3S17 C;  4QIW D;  4C3I C;  3M4O K;  1I6H K;  3HOW K;  2JA7 C;  3K7A C;  3RZO K;  1BDF A;  1TWC C;  5C44 C;  3S15 C;  2O5I A;  2VUM K;  4OIN A;  2WAQ L;  4GZY A;  3HOV K;  4AYB D;  2JA6 K;  1I6V A;  1I3Q K;  2CW0 A;  5IP9 C;  2E2H C;  3GTM C;  2Y0S D;  4C3J C;  2JA6 C;  4A3D C;  5M5W K;  4MEY A;  4G7H A;  2E2H K;  4A3C K;  1HQM A;  5C3E C;  2BE5 A;  3S1R K;  3GTL K;  3CQZ C;  5TMF A;  4A3I K;  2JA5 K;  4A3G C;  5IYD K;  4OIR A;  3H3V L;  4BBR K;  4OIQ A;  4A3C C;  4LJZ A;  3GTL C;  2R92 C;  1TWH K;  4A3J K;  4A3I C;  2JA5 C;  3GTG C;  3EQL A;  3I4N C;  4Q4Z A;  2PPB A;  2A69 A;  3H0G K;  2YU9 K;  3I4M K;  5M5Y K;  1TWH C;  4YFK A;  2B63 C;  3I4N K;  4XSZ A;  3GTQ K;  4QJV B;  1XPP A;  4Y7N K;  3S1Q K;  2NVT C;  2NVX K;  4A3B K;  4X6A K;  2NVY C;  2A6H A;  2R93 C;  4YFX A;  4C3I K;  3GTO K;  2JA7 K;  4JK1 A;  3M4O C;  3HKZ D;  3S17 K;  4Y52 K;  1SMY A;  3M3Y C;  3HOY C;  4BXX C;  3DXJ A;  4LK0 A;  4A3M C;  1I3Q C;  4OIP A;  1WCM K;  4G7Z A;  3S2D C;  4MEX A;  5TMC A;  3S14 K;  4BXX K;  4A3D K;  4A3M K;  2R7Z K;  3GTJ K;  4C3J K;  5FLM C;  3WOD A;  1Y1V K;  1K83 C;  2E2I K;  4NOI A;  2R7Z C;  1ZYR A;  4BY7 C;  5FJ8 K;  4KN7 A;  4BBS K;  3H3V D;  1Y1V C;  1TWG K;  2R92 K;  5IYB C;  4KN4 A;  3S2H C;  4G7O A;  4BY7 K;  4ZH4 A;  4Q5S A;  5C4X C;  3GTQ C;  4QIW L;  5IYB K;  3GTP K;  4A3F C;  2B63 K;  2PA8 L;  5IYC K;  1YNN A;  2JA8 K;  3HOU K;  5C4X K;  3PO3 K;  2NVY K;  4A3F K;  1Y1W K;  2A6E A;  4Y7N C;  1R9T C;  3S15 K;  2R93 K;  3GTO C;  3S1N C;  4OIO A;  1Y1W C;  1SFO C;  4C2M K;  5C44 K;  4A93 C;  4A3L K;  2PA8 D;  5IP7 K;  3HOY K;  5IP9 K;  3S16 C;  3M3Y K;  4YFN A;  3HOZ K;  4A3E C;  3HOX C;  3S14 C;  1I50 C;  1WCM C;  1TWF K;  4AYB L;  3S2D K;  3S1R C;  4LK1 A;  3CQZ K;  4XLN A;  1I50 K;  4A3K K;  4BBR C;  1TWF C;  4MQ9 A;  5C4J K;  4YG2 A;  2E2J K;  1K83 K;  2YU9 C;  4A3J C;  3I4M C;  3S1M C;  4A3K C;  3GTK C;  1TWA C;  5C4J C;  2E2J C;  4BY1 C;  4XSX A;  1YNJ A;  2PMZ D;  5M5X K;  3S2H K;  3RZO C;  4LLG A;  3HOW C;  4A3B C;  3K7A K;  3HOU C;  2VUM C;  1TWC K;  4KMU A;  3FKI K;  5IYC C;  2JA8 C;  1R9T K;  2WB1 D;  3PO3 C;  3HOV C;  3GTM K;  4Y52 C;  3HKZ L;  3FKI C;  2NVQ K;  4C2M C;  4A3L C;  1SFO K;  4XLP A;  4A93 K;  5IP7 C;  3S1N K;  5D4D A;  5IYD C;  5C3E K;  5M3F K;  2NVQ C;  4A3G K;  2A68 A;  4C3H C;  4A3E K;  3S16 K;  3HOX K;  3GTJ C;  4QJV A;  2E2I C;  3H0G C;  3HOZ C;  4C3H K;  4BBS C;  5FLM K;  2WB1 L;  3GTG K;  1IW7 A;  2WAQ D;  3PO2 C;  3RZD K;  1TWG C;  5M3M K;  3S1Q C; 
#chains in the Genus database with same CATH topology
 1ZQ1 C;  2NVT K;  4P5A A;  4BY1 K;  3S1M K;  3GTK K;  2O5J A;  4QIW D;  1I6H K;  2NVY A;  3K7A C;  3L4K A;  4OIN A;  5JFE A;  5HL8 A;  4AYB D;  2E2H C;  3GTM C;  4IOA S;  4AH6 A;  4MEY A;  4IO9 S;  5L46 A;  3S1R K;  2BE5 A;  3CQZ C;  4A3I K;  2JA5 K;  4A3G C;  2B63 A;  4O2D A;  3A8J A;  1EFW A;  2PPB A;  4KB4 A;  4YFK A;  4GTL A;  4KM9 A;  3I4N K;  2R92 A;  4GTE A;  4QJV B;  3AD9 C;  4X6A K;  2A6H A;  4YFX A;  4JK1 A;  3M4O C;  3HKZ D;  3DLL S;  5IOQ A;  1XZQ B;  1VRQ C;  4KB2 A;  4BXX C;  3DXJ A;  1I3Q C;  3TTG A;  3MML B;  4IOC S;  2ZJP S;  4PAB A;  4A3D K;  3PIO S;  3N3Y A;  3T00 A;  5FLM C;  4KN7 A;  1Y1V C;  2V6S A;  3GDZ A;  3OEP A;  3T02 A;  3GIR A;  1F93 A;  5C4X C;  3FHZ A;  2PA8 L;  5IYC K;  2ZUF A;  2JA5 A;  1TWF A;  2RH6 A;  4WCE S;  4C2M K;  4A3L K;  3HOY K;  3CAG A;  3S16 C;  1I50 C;  1WCM C;  4XLN A;  1TWF C;  5C4J K;  4YG2 A;  1K83 K;  2CFA A;  4A3J C;  1F7V A;  3AD7 C;  4A3K C;  3TFH A;  4BY1 C;  3FOF A;  4XSX A;  5M5X K;  3HOW C;  2FQO A;  2VUM C;  4GTD A;  3FKI K;  4KMD A;  3NUH A;  3GTQ A;  1XZP A;  1SFO K;  4WFB S;  4XLP A;  1WSV A;  1JVI A;  5CJ9 A;  3T01 A;  4XCH A;  2GSU A;  3GTM A;  2NVQ C;  5JVG S;  3GEI A;  1WOO A;  3GTO A;  3ORE A;  4QJV A;  4C3H K;  3SZY A;  2GSN A;  3PO2 C;  3RZD K;  1TWG C;  4ILD A;  5M3M K;  2JA6 A;  2NVX C;  2Y0S L;  3GTP C;  3AD8 C;  1DCP A;  4C3I C;  1KQ4 A;  3HOW K;  4M1X A;  3RZO K;  3GTK A;  1O2A A;  3HOV K;  1I3Q K;  5IP9 C;  4KAW X;  4U67 S;  2Y0S D;  1J6W A;  2L3U A;  2JA6 C;  4A3D C;  2XCR B;  5C3E C;  3GTL K;  5IYD K;  1WOS A;  4OIR A;  4OIQ A;  4LJZ A;  1EH1 A;  1TWH K;  2ZUE A;  3I4N C;  3H0G K;  4Q4Z A;  3I4M K;  4GTC A;  5M5Y K;  2B63 C;  2GAG C;  3A8K A;  1IL2 A;  2NVT C;  1EQR A;  4C3I K;  3GTO K;  1J6X A;  3HOY C;  3PIP S;  1DD5 A;  5EGH A;  2ZFZ A;  4LK0 A;  4P9S A;  3BP8 C;  1PJ7 A;  1WIH A;  4PAA A;  3SZZ A;  5TMC A;  1PJ6 A;  1TWC A;  2W7V A;  4C3J K;  1Y1V K;  3BP3 A;  1F9N A;  5IOT A;  4NOI A;  1ZYR A;  4BBS K;  1JOE A;  5IYB C;  4KN4 A;  3S2H C;  4BY7 K;  1ZBS A;  4ZH4 A;  2V6T A;  4QIW L;  4GTF A;  5IOR A;  3PO3 K;  1Y1W A;  1XZQ A;  1UV7 A;  1O25 A;  2R93 K;  4GTA A;  5C44 K;  4RMF A;  1SFO C;  2PA8 D;  5EGE A;  3JST A;  3M3Y K;  4G0U A;  1B4A A;  1WSR A;  1TWF K;  4AYB L;  3S2D K;  5DM6 S;  3L4J A;  3GSI A;  2R7Z A;  1ZXO A;  3TFJ A;  4BBR C;  1WCM A;  3I4M C;  1SFO A;  2E2J C;  1YNJ A;  4LLG A;  4A3B C;  3HOU C;  2JA8 C;  3S0X A;  3OPF A;  3N0B A;  3HOV C;  1DCH A;  3GTM K;  4Y52 C;  2NVQ K;  1ZVU A;  1IE0 A;  4KM8 A;  3S1N K;  3H0G A;  5M3F K;  4A3G K;  1R9T A;  2A68 A;  1BJT A;  2P8T A;  2JA7 A;  3HOX K;  3GTJ C;  2WB1 L;  5HL7 S;  3GEE A;  1J98 A;  1V5V A;  3Q3Q A;  1I6H C;  4G0W A;  2XCO A;  3S17 C;  2ZJQ S;  1O28 A;  2JA7 C;  4BKW A;  5C44 C;  3S15 C;  2O5I A;  3GTP A;  2WAQ L;  4GZY A;  2JA6 K;  1I6V A;  1O26 A;  5M5W K;  2FQT A;  3LAJ A;  4G7H A;  3GEH A;  4FM9 A;  3H3V L;  4BBR K;  1VLO A;  4A3C C;  4J3N A;  4A3J K;  4A3I C;  2JA5 C;  3GTG C;  3EQL A;  4WIL A;  2A69 A;  3G4A A;  2YU9 K;  3GTQ K;  3ERE D;  3S1Q K;  4Y7N K;  1F7U A;  1PJ5 A;  2NVX K;  4A3B K;  3N0C A;  1WQG A;  2JA7 K;  4DDQ A;  1SMY A;  1WOP A;  1DCO A;  2L5N A;  4OIP A;  1K83 A;  2KPU A;  3S14 K;  4BXX K;  2V6U A;  4A3M K;  3GTJ K;  3WOD A;  3TFI A;  2E2I K;  3HXA A;  2R7Z C;  5FJ8 K;  3H3V D;  1HI9 A;  1TWG K;  2R92 K;  5JVO A;  5DM7 S;  1USM A;  4G0V A;  4LOW A;  4WFN S;  4Q5S A;  1C0A A;  3GTQ C;  3GTP K;  3A8I A;  2B63 K;  3HOU K;  1YNN A;  2GAH C;  3V4G A;  5C4X K;  4KMH A;  2NVY K;  1EI6 A;  4A3F K;  3GTO C;  1Y1W C;  2CFA B;  4KC6 A;  2JH3 A;  1TWG A;  1RU0 A;  3HOZ K;  1XXC A;  3HOX C;  3S14 C;  5CHP A;  4LK1 A;  3GTJ A;  1I50 K;  4A3K K;  2E2J K;  2YU9 C;  3S1M C;  4BLB A;  4KAS A;  3GTK C;  1INN A;  2PMZ D;  3RZO C;  3CF5 S;  3LYW A;  1Y1V A;  1TWC K;  4KMU A;  5IYC C;  1R9T K;  3PO3 C;  3ADA C;  2XCQ A;  3HKZ L;  3FKI C;  5JVH S;  1WQF A;  4GTB A;  2YU9 A;  2D6F C;  5IYD C;  5C3E K;  4C3H C;  4A3E K;  3S16 K;  4KMA A;  1O24 A;  1XXB A;  3H0G C;  1WQH A;  5FLM K;  4BBS C;  1IQ0 A;  2ZJR S;  1IW7 A;  2WAQ D;  3GTG K;  4GT9 A;  4X6A C;  3RZD C;  3PO2 K;  1TWA K;  4FZB A;  2PMZ L;  1L0W A;  1BS2 A;  4GFQ A;  1XXA A;  3M4O K;  3GTL A;  3LAP A;  1BDF A;  2GSO A;  2E2H A;  1TWC C;  3AQP A;  2VUM K;  2EBB A;  2CW0 A;  1VJE A;  4WJ3 M;  1O2B A;  4C3J C;  2VUM A;  2R93 A;  2RGR A;  2E2H K;  4A3C K;  1HQM A;  5E68 A;  5TMF A;  3G4C A;  3GTL C;  2R92 C;  3VA7 A;  4KAR A;  1TWH C;  4XSZ A;  3GTG A;  1XPP A;  2NVY C;  3FOE A;  2R93 C;  3AQO A;  2PHC B;  3S17 K;  4KDD A;  1O27 A;  4Y52 K;  3IPJ A;  3M3Y C;  4WFA S;  2Y3P A;  4A3M C;  1J6V A;  1WCM K;  4G7Z A;  3S2D C;  1TWH A;  4MEX A;  2R7Z K;  3CQZ A;  1K83 C;  4BY7 C;  2KQ1 A;  4P5B A;  4G7O A;  2P5M A;  1USO A;  1FEU A;  5IYB K;  1ISE A;  4A3F C;  1IS1 A;  2JA8 K;  1IBA A;  1JQW A;  1Y1W K;  2A6E A;  4Y7N C;  1R9T C;  4LR2 A;  3BUE A;  3S15 K;  3S1N C;  4OIO A;  4BLA A;  1TWA A;  4A93 C;  4C45 A;  5IP7 K;  1I3Q A;  5IP9 K;  1O29 A;  4YFN A;  1XZP B;  4A3E C;  4LQY A;  3S1R C;  3CQZ K;  1O2F B;  5IOS A;  2KWA A;  3AH5 A;  2KXY A;  4MQ9 A;  1EK8 A;  1TWA C;  5C4J C;  1G51 A;  1VGX A;  1WOR A;  4KAT A;  3S2H K;  4WJ4 A;  2E2I A;  1X31 C;  1YX2 A;  1B4B A;  3K7A K;  1VH2 A;  2WB1 D;  1BGW A;  1GE9 A;  4C2M C;  4A3L C;  4A93 K;  5IP7 C;  5D4D A;  1AB4 A;  3LPX A;  5HQH A;  1I50 A;  3FKI A;  2E2I C;  3HOZ C;  2NVX A;  5TJ3 A;  4WF9 S;  3QX3 A;  1YCL A;  3S1Q C; 
#chains in the Genus database with same CATH homology
 2NVX C;  4X6A C;  3RZD C;  2NVT K;  1TWA K;  1I6H C;  4BY1 K;  2PMZ L;  3PO2 K;  3S1M K;  2Y0S L;  3GTK K;  2O5J A;  3GTP C;  3S17 C;  4QIW D;  4C3I C;  3M4O K;  1I6H K;  3HOW K;  2JA7 C;  3K7A C;  3RZO K;  1BDF A;  1TWC C;  5C44 C;  3S15 C;  2O5I A;  2VUM K;  4OIN A;  2WAQ L;  4GZY A;  3HOV K;  4AYB D;  2JA6 K;  1I6V A;  1I3Q K;  2CW0 A;  5IP9 C;  2E2H C;  3GTM C;  2Y0S D;  4C3J C;  2JA6 C;  4A3D C;  5M5W K;  4MEY A;  4G7H A;  2E2H K;  4A3C K;  1HQM A;  5C3E C;  2BE5 A;  3S1R K;  3GTL K;  3CQZ C;  5TMF A;  4A3I K;  2JA5 K;  4A3G C;  5IYD K;  4OIR A;  3H3V L;  4BBR K;  4OIQ A;  4A3C C;  4LJZ A;  3GTL C;  2R92 C;  1TWH K;  4A3J K;  4A3I C;  2JA5 C;  3GTG C;  3EQL A;  3I4N C;  4Q4Z A;  2PPB A;  2A69 A;  3H0G K;  2YU9 K;  3I4M K;  5M5Y K;  1TWH C;  4YFK A;  2B63 C;  3I4N K;  4XSZ A;  3GTQ K;  4QJV B;  1XPP A;  4Y7N K;  3S1Q K;  2NVT C;  2NVX K;  4A3B K;  4X6A K;  2NVY C;  2A6H A;  2R93 C;  4YFX A;  4C3I K;  3GTO K;  2JA7 K;  4JK1 A;  3M4O C;  3HKZ D;  3S17 K;  4Y52 K;  1SMY A;  3M3Y C;  3HOY C;  4BXX C;  3DXJ A;  4LK0 A;  4A3M C;  1I3Q C;  4OIP A;  1WCM K;  4G7Z A;  3S2D C;  4MEX A;  5TMC A;  3S14 K;  4BXX K;  4A3D K;  4A3M K;  2R7Z K;  3GTJ K;  4C3J K;  5FLM C;  3WOD A;  1Y1V K;  1K83 C;  2E2I K;  4NOI A;  2R7Z C;  1ZYR A;  4BY7 C;  5FJ8 K;  4KN7 A;  4BBS K;  3H3V D;  1Y1V C;  1TWG K;  2R92 K;  5IYB C;  4KN4 A;  3S2H C;  4G7O A;  4BY7 K;  4ZH4 A;  4Q5S A;  5C4X C;  3GTQ C;  4QIW L;  5IYB K;  3GTP K;  4A3F C;  2B63 K;  2PA8 L;  5IYC K;  1YNN A;  2JA8 K;  3HOU K;  5C4X K;  3PO3 K;  2NVY K;  4A3F K;  1Y1W K;  2A6E A;  4Y7N C;  1R9T C;  3S15 K;  2R93 K;  3GTO C;  3S1N C;  4OIO A;  1Y1W C;  1SFO C;  4C2M K;  5C44 K;  4A93 C;  4A3L K;  2PA8 D;  5IP7 K;  3HOY K;  5IP9 K;  3S16 C;  3M3Y K;  4YFN A;  3HOZ K;  4A3E C;  3HOX C;  3S14 C;  1I50 C;  1WCM C;  1TWF K;  4AYB L;  3S2D K;  3S1R C;  4LK1 A;  3CQZ K;  4XLN A;  1I50 K;  4A3K K;  4BBR C;  1TWF C;  4MQ9 A;  5C4J K;  4YG2 A;  2E2J K;  1K83 K;  2YU9 C;  4A3J C;  3I4M C;  3S1M C;  4A3K C;  3GTK C;  1TWA C;  5C4J C;  2E2J C;  4BY1 C;  4XSX A;  1YNJ A;  2PMZ D;  5M5X K;  3S2H K;  3RZO C;  4LLG A;  3HOW C;  4A3B C;  3K7A K;  3HOU C;  2VUM C;  1TWC K;  4KMU A;  3FKI K;  5IYC C;  2JA8 C;  1R9T K;  2WB1 D;  3PO3 C;  3HOV C;  3GTM K;  4Y52 C;  3HKZ L;  3FKI C;  2NVQ K;  4C2M C;  4A3L C;  1SFO K;  4XLP A;  4A93 K;  5IP7 C;  3S1N K;  5D4D A;  5IYD C;  5C3E K;  5M3F K;  2NVQ C;  4A3G K;  2A68 A;  4C3H C;  4A3E K;  3S16 K;  3HOX K;  3GTJ C;  4QJV A;  2E2I C;  3H0G C;  3HOZ C;  4C3H K;  4BBS C;  5FLM K;  2WB1 L;  3GTG K;  1IW7 A;  2WAQ D;  3PO2 C;  3RZD K;  1TWG C;  5M3M K;  3S1Q C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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