4XSZA

Crystal structure of cbr 9393 bound to escherichia coli rna polymerase holoenzyme
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
pubmed doi rcsb
molecule tags Transcription/antibiotic
source organism Escherichia coli (strain k12)
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 42
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4xszA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4xszA01
4A3KC 1TWFK 2BE5A 3S1RK 4YFKA 4BBRC 1HQMA 4LLGA 4C3IC 4YFXA 3S16C 5IYDC 4MEXA 4C3IK 1I6VA 3S16K 4ZH4A 4BBSK 2R93K 5IYDK 1TWCC 2R92C 3S1NC 1TWCK 2R92K 1TWAC 2O5JA 3S1NK 1I3QK 1TWAK 3S14C 3GTOC 3GTOK 1ZYRA 2PA8D 3GTJC 5IYCC 3M4OK 1YNNA 3GTJK 5IYCK 1WCMC 4GZYA 1WCMK 5M5WK 2JA6K 2B63K 4A3GC 1K83C 2WAQL 4A3GK 4Y52C 4G7HA 4OINA 4Y52K 1TWGC 4LK0A 1TWGK 2PMZD 4A3LC 4AYBL 4A3LK 4A3JK 4C2MK 4A3EC 3H0GC 5M3MK 2NVTK 5TMCA 3GTPC 3H0GK 4A3EK 3GTPK 4JK1A 4XSZA 1YNJA 4A3CC 2R93C 2NVXC 4BBSC 5TMFA 4X6AC 3FKIK 2NVXK 3HOYC 5M5YK 4A3CK 4X6AK 4A3IC 3HOYK 4A3FC 2E2HC 4A3IK 4OIPA 4A3FK 2E2HK 3GTKK 1I3QC 1I6HC 3HOVC 1I6HK 3HOVK 4Y7NK 4A3BK 4XLNA 3HKZL 3PO3C 2JA5K 1I50C 2CW0A 2WAQD 3PO3K 1I50K 4A93C 3S2HC 4A93K 2JA6C 1Y1WC 2Y0SD 2B63C 3HOWC 1Y1WK 3S2HK 3HOWK 1BDFA 3HOZC 4KN4A 3H3VD 5M5XK 2YU9C 4KN7A 3S1RC 2O5IA 2YU9K 4KMUA 4BY1K 3HOZK 2PPBA 4YG2A 3I4MC 4OIOA 3I4MK 4A3JC 3S1QC 3HOXK 3S1QK 2VUMK 3EQLA 4C2MC 2NVTC 3DXJA 5IYBC 2WB1L 5IYBK 4A3MC 4A3MK 3S1MK 3FKIC 1IW7A 4G7ZA 3GTKC 3RZOC 3RZOK 3WODA 1XPPA 5C44K 3S17C 2NVQC 3M4OC 5IP7K 4LK1A 4Y7NC 1SFOC 2NVQK 1SFOK 3M3YC 2NVYC 4QIWL 3HOUK 4MEYA 2NVYK 3CQZC 4MQ9A 2JA5C 2PA8L 3CQZK 3M3YK 3GTGC 1TWHC 4QJVA 3S15C 1TWHK 3GTGK 3S15K 5D4DA 4AYBD 3K7AC 4QJVB 2JA8C 4BXXC 3K7AK 2JA8K 4BY1C 4BXXK 3RZDK 3GTQK 4Q5SA 2A68A 4BY7C 2PMZL 2WB1D 3PO2C 3HOXC 1R9TC 4C3JC 3PO2K 2VUMC 4A3KK 2A6HA 4C3JK 1R9TK 4BY7K 2E2JC 4BBRK 5M3FK 1Y1VC 2E2JK 5C4JC 1Y1VK 4NOIA 2A6EA 5C4JK 5C4XC 5C4XK 2JA7C 5FJ8K 2JA7K 2R7ZC 2A69A 3I4NC 2R7ZK 4YFNA 3GTLC 3GTMK 4QIWD 3GTLK 3S14K 5C44C 3HKZD 5FLMC 1SMYA 4C3HC 5IP7C 4Q4ZA 3GTMC 3S2DC 4XSXA 4C3HK 5FLMK 3S2DK 3HOUC 5IP9C 3I4NK 5IP9K 1K83K 2E2IC 2E2IK 4A3DC 4OIRA 3S17K 4A3DK 2Y0SL 4G7OA 4LJZA 4XLPA 4OIQA 3H3VL 3RZDC 3GTQC 4A3BC 3S1MC 5C3EC 5C3EK 1TWFC
chains in the Genus database with same CATH superfamily
4FZBA 4YFXA 4C3IC 4C3IK 4ZH4A 3GTJA 1TWAC 1TWAK 3S14C 3GTOC 3GTOK 4ILDA 1ZYRA 1YNNA 2XCRB 2B63K 4A3GC 1K83C 4A3GK 4Y52C 4KMHA 4Y52K 2R93A 2NVXA 1WQHA 3S0XA 4WJ4A 3GTPC 3FOEA 2E2HA 1TWCA 3GTPK 4JK1A 1I3QA 4KB4A 3HOYC 5M5YK 1I50A 3HOYK 4A3FC 3A8KA 4OIPA 4A3FK 1C0AA 1WOOA 3HOVC 5HL8A 3HOVK 3HKZL 5JVOA 3PO3C 4BKWA 3PO3K 1TWGA 3S2HC 2JA6C 3S2HK 1J6VA 1F7VA 3OEPA 3H0GA 4WF9S 5HL7S 4GT9A 4BY1K 3AD7C 1VJEA 5HQHA 3DXJA 3TTGA 1DCHA 3N3YA 3FKIC 2P5MA 3GDZA 4GTBA 2EBBA 3S17C 2CFAB 5IP7K 3S17K 1O28A 1TWHC 2ZFZA 1TWHK 1WQGA 5E68A 3K7AC 3K7AK 3GEEA 5TJ3A 1IS1A 1VRQC 2WB1D 1R9TC 1R9TK 4LOWA 1WOSA 1Y1VC 1Y1VK 4BLBA 2A6EA 3PIOS 4KM9A 5FJ8K 1SFOA 4KB2A 2A69A 1B4BA 5C44C 1WSRA 3N0BA 1VLOA 5FLMC 1SMYA 2V6TA 4Q4ZA 5FLMK 3ERED 3HOUC 2V6UA 4KDDA 4G7OA 4LJZA 3LAPA 3RZDC 4PABA 3I4NC 3I4NK 2GSNA 4KMAA 1RU0A 4GTLA 4LLGA 4WFBS 2R93K 2KXYA 3PIPS 3Q3QA 1TWCC 2R92C 1WCMA 1TWCK 2R92K 5CJ9A 1I3QK 1DCPA 1ZQ1C 5IYCC 5IYCK 4GZYA 5M5WK 2ZJQS 2WAQL 4G7HA 1TWGC 1JOEA 4LK0A 1TWGK 3A8IA 4A3JK 3H0GC 2NVTK 4XCHA 5TMCA 3H0GK 1XZQA 1YNJA 4A3CC 4GTEA 5IOTA 5TMFA 4A3CK 1BJTA 3GEIA 4GTFA 1UV7A 1B4AA 1F93A 1DD5A 1BS2A 1WSVA 1Y1WC 2B63C 3OPFA 2L5NA 1Y1WK 1BDFA 3HOZC 1VH2A 3H3VD 2YU9C 1O26A 3HOZK 2YU9K 3HOXK 4KMDA 2GSOA 1O29A 3GTKA 5IYBC 1ZXOA 1WIHA 5IYBK 4A3MC 4BLAA 4A3MK 1INNA 1O24A 2NVYA 5EGHA 3HXAA 3CQZA 2JA5A 3RZOC 1XZPA 2ZUFA 3RZOK 3WODA 1SFOC 1IQ0A 1SFOK 3GIRA 3GTGC 4QJVA 1HI9A 1ZVUA 3GTGK 4IO9S 2VUMA 4AYBD 4C45A 4BY1C 1EFWA 4Q5SA 4IOAS 3QX3A 4IOCS 4C3JC 4A3KK 4C3JK 3VA7A 2R7ZA 2E2JC 4BBRK 2E2JK 5C4JC 1J6XA 5C4JK 3GTMA 5C4XC 2JH3A 5C4XK 3BP3A 4M1XA 4QIWD 2E2IA 4C3HC 5IP7C 4C3HK 4XSXA 4GTCA 5IP9C 1JQWA 5IP9K 3CAGA 3GTQA 3AD9C 5DM6S 1J6WA 2KPUA 4OIRA 1KQ4A 4KC6A 2ZJRS 4OIQA 3H3VL 3AQOA 4A3BC 4U67S 5C3EC 4A3BK 1WQFA 5C3EK 1TWFC 4P9SA 4WFAS 2BE5A 1TWFK 4YFKA 1TWAA 3JSTA 4KATA 3TFIA 3GTLA 3S16C 4LR2A 5IYDC 4MEXA 3S16K 4BBSK 1PJ6A 5IYDK 2O5JA 5DM7S 1K83A 3L4KA 1O2BA 1YX2A 3GTJC 2ZJPS 3GTJK 4KM8A 5JFEA 3GTPA 4OINA 2D6FC 4AYBL 1FEUA 4KASA 4C2MK 4A3EC 5M3MK 3T00A 4A3EK 3OREA 2R93C 2NVXC 1O27A 3N0CA 2NVXK 4A3IC 2ZUEA 1WOPA 2E2HC 4A3IK 3GTKK 2E2HK 1I3QC 4G0VA 3GEHA 2JA6A 5IOSA 4GTDA 2P8TA 4Y7NK 4LQYA 4XLNA 4GFQA 1IBAA 2JA5K 1I50C 2CW0A 1I50K 4A93C 1ZBSA 1XXAA 4A93K 2Y0SD 1O2AA 1BGWA 2RH6A 5M5XK 1F7UA 2O5IA 4WILA 5IOQA 3MMLB 3I4MC 4OIOA 3I4MK 3FKIA 4A3JC 4DDQA 2VUMK 2NVTC 2WB1L 1XXCA 1O25A 2KQ1A 1PJ5A 4G7ZA 1TWHA 1JVIA 2GAHC 4PAAA 1X31C 3M4OC 3GTMK 3M4OK 1EI6A 4WFNS 1EK8A 3M3YC 1XZPB 4MEYA 2RGRA 3M3YK 2Y3PA 1O2FB 5D4DA 3LPXA 1R9TA 4QJVB 3TFHA 2JA8C 2JA8K 3GSIA 4KAWX 3GTQK 2A68A 3HOXC 3SZZA 2A6HA 1USOA 5M3FK 5CHPA 3AQPA 1G51A 4G0WA 4YFNA 3GTLC 3FHZA 4G0UA 3GTLK 3S14K 1PJ7A 2FQTA 3G4AA 1K83K 3T02A 2Y0SL 5L46A 3LAJA 1ISEA 2R92A 3S1RC 2JA7A 4A3KC 3S1RK 4BBRC 5EGEA 1XXBA 1HQMA 3CF5S 3G4CA 1EQRA 2XCOA 1I6VA 1GE9A 1WORA 3S1NC 3S1NK 3T01A 2PA8D 1WCMC 3BP8C 2XCQA 1WCMK 3V4GA 2JA6K 5JVGS 2PMZD 4A3LC 4A3LK 1DCOA 5IORA 4RMFA 2KWAA 3NUHA 2W7VA 2V6SA 4XSZA 3FKIK 4BBSC 4X6AC 3GTOA 4X6AK 3AD8C 1I6HC 1EH1A 1Y1WA 3LYWA 1I6HK 2B63A 2YU9A 4P5AA 4GTAA 2WAQD 5JVHS 3HOWC 4AH6A 3BUEA 3HOWK 2PHCB 4KN4A 4KN7A 4KMUA 1YCLA 1J98A 2PPBA 4YG2A 4FM9A 2FQOA 3S1QC 3S1QK 3EQLA 4C2MC 3L4JA 1IL2A 3AH5A 4WCES 1IW7A 1VGXA 2CFAA 3FOFA 2GAGC 3GTGA 3GTKC 1XPPA 5C44K 1XZQB 3TFJA 2NVQC 4LK1A 4Y7NC 2NVQK 2NVYC 4QIWL 4J3NA 3HOUK 2NVYK 3CQZC 4MQ9A 2JA5C 2PA8L 3A8JA 3CQZK 4WJ3M 1AB4A 4P5BA 3S15C 3S15K 1IE0A 4BXXC 4BXXK 3RZDK 3SZYA 4BY7C 2PMZL 3PO2C 4BY7K 4O2DA 3PO2K 2VUMC 4NOIA 4KARA 2JA7C 3ADAC 2L3UA 2JA7K 2R7ZC 2GSUA 2R7ZK 3HKZD 3GTMC 3S2DC 3S2DK 1USMA 1V5VA 2E2IC 2E2IK 3DLLS 3IPJA 4A3DC 1TWFA 4A3DK 4XLPA 1F9NA 1Y1VA 3GTQC 3S1MC 3S1MK 1L0WA
chains in the Genus database with same CATH topology
4A3KC 1TWFK 2BE5A 3S1RK 4YFKA 4BBRC 1HQMA 4LLGA 4C3IC 4YFXA 3S16C 5IYDC 4MEXA 4C3IK 1I6VA 3S16K 4ZH4A 4BBSK 2R93K 5IYDK 1TWCC 2R92C 3S1NC 1TWCK 2R92K 1TWAC 2O5JA 3S1NK 1I3QK 1TWAK 3S14C 3GTOC 3GTOK 1ZYRA 2PA8D 3GTJC 5IYCC 3M4OK 1YNNA 3GTJK 5IYCK 1WCMC 4GZYA 1WCMK 5M5WK 2JA6K 2B63K 4A3GC 1K83C 2WAQL 4A3GK 4Y52C 4G7HA 4OINA 4Y52K 1TWGC 4LK0A 1TWGK 2PMZD 4A3LC 4AYBL 4A3LK 4A3JK 4C2MK 4A3EC 3H0GC 5M3MK 2NVTK 5TMCA 3GTPC 3H0GK 4A3EK 3GTPK 4JK1A 4XSZA 1YNJA 4A3CC 2R93C 2NVXC 4BBSC 5TMFA 4X6AC 3FKIK 2NVXK 3HOYC 5M5YK 4A3CK 4X6AK 4A3IC 3HOYK 4A3FC 2E2HC 4A3IK 4OIPA 4A3FK 2E2HK 3GTKK 1I3QC 1I6HC 3HOVC 1I6HK 3HOVK 4Y7NK 4A3BK 4XLNA 3HKZL 3PO3C 2JA5K 1I50C 2CW0A 2WAQD 3PO3K 1I50K 4A93C 3S2HC 4A93K 2JA6C 1Y1WC 2Y0SD 2B63C 3HOWC 1Y1WK 3S2HK 3HOWK 1BDFA 3HOZC 4KN4A 3H3VD 5M5XK 2YU9C 4KN7A 3S1RC 2O5IA 2YU9K 4KMUA 4BY1K 3HOZK 2PPBA 4YG2A 3I4MC 4OIOA 3I4MK 4A3JC 3S1QC 3HOXK 3S1QK 2VUMK 3EQLA 4C2MC 2NVTC 3DXJA 5IYBC 2WB1L 5IYBK 4A3MC 4A3MK 3S1MK 3FKIC 1IW7A 4G7ZA 3GTKC 3RZOC 3RZOK 3WODA 1XPPA 5C44K 3S17C 2NVQC 3M4OC 5IP7K 4LK1A 4Y7NC 1SFOC 2NVQK 1SFOK 3M3YC 2NVYC 4QIWL 3HOUK 4MEYA 2NVYK 3CQZC 4MQ9A 2JA5C 2PA8L 3CQZK 3M3YK 3GTGC 1TWHC 4QJVA 3S15C 1TWHK 3GTGK 3S15K 5D4DA 4AYBD 3K7AC 4QJVB 2JA8C 4BXXC 3K7AK 2JA8K 4BY1C 4BXXK 3RZDK 3GTQK 4Q5SA 2A68A 4BY7C 2PMZL 2WB1D 3PO2C 3HOXC 1R9TC 4C3JC 3PO2K 2VUMC 4A3KK 2A6HA 4C3JK 1R9TK 4BY7K 2E2JC 4BBRK 5M3FK 1Y1VC 2E2JK 5C4JC 1Y1VK 4NOIA 2A6EA 5C4JK 5C4XC 5C4XK 2JA7C 5FJ8K 2JA7K 2R7ZC 2A69A 3I4NC 2R7ZK 4YFNA 3GTLC 3GTMK 4QIWD 3GTLK 3S14K 5C44C 3HKZD 5FLMC 1SMYA 4C3HC 5IP7C 4Q4ZA 3GTMC 3S2DC 4XSXA 4C3HK 5FLMK 3S2DK 3HOUC 5IP9C 3I4NK 5IP9K 1K83K 2E2IC 2E2IK 4A3DC 4OIRA 3S17K 4A3DK 2Y0SL 4G7OA 4LJZA 4XLPA 4OIQA 3H3VL 3RZDC 3GTQC 4A3BC 3S1MC 5C3EC 5C3EK 1TWFC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3K C;  1TWF K;  2BE5 A;  3S1R K;  4YFK A;  4BBR C;  1HQM A;  4LLG A;  4C3I C;  4YFX A;  3S16 C;  5IYD C;  4MEX A;  4C3I K;  1I6V A;  3S16 K;  4ZH4 A;  4BBS K;  2R93 K;  5IYD K;  1TWC C;  2R92 C;  3S1N C;  1TWC K;  2R92 K;  1TWA C;  2O5J A;  3S1N K;  1I3Q K;  1TWA K;  3S14 C;  3GTO C;  3GTO K;  1ZYR A;  2PA8 D;  3GTJ C;  5IYC C;  3M4O K;  1YNN A;  3GTJ K;  5IYC K;  1WCM C;  4GZY A;  1WCM K;  5M5W K;  2JA6 K;  2B63 K;  4A3G C;  1K83 C;  2WAQ L;  4A3G K;  4Y52 C;  4G7H A;  4OIN A;  4Y52 K;  1TWG C;  4LK0 A;  1TWG K;  2PMZ D;  4A3L C;  4AYB L;  4A3L K;  4A3J K;  4C2M K;  4A3E C;  3H0G C;  5M3M K;  2NVT K;  5TMC A;  3GTP C;  3H0G K;  4A3E K;  3GTP K;  4JK1 A;  4XSZ A;  1YNJ A;  4A3C C;  2R93 C;  2NVX C;  4BBS C;  5TMF A;  4X6A C;  3FKI K;  2NVX K;  3HOY C;  5M5Y K;  4A3C K;  4X6A K;  4A3I C;  3HOY K;  4A3F C;  2E2H C;  4A3I K;  4OIP A;  4A3F K;  2E2H K;  3GTK K;  1I3Q C;  1I6H C;  3HOV C;  1I6H K;  3HOV K;  4Y7N K;  4A3B K;  4XLN A;  3HKZ L;  3PO3 C;  2JA5 K;  1I50 C;  2CW0 A;  2WAQ D;  3PO3 K;  1I50 K;  4A93 C;  3S2H C;  4A93 K;  2JA6 C;  1Y1W C;  2Y0S D;  2B63 C;  3HOW C;  1Y1W K;  3S2H K;  3HOW K;  1BDF A;  3HOZ C;  4KN4 A;  3H3V D;  5M5X K;  2YU9 C;  4KN7 A;  3S1R C;  2O5I A;  2YU9 K;  4KMU A;  4BY1 K;  3HOZ K;  2PPB A;  4YG2 A;  3I4M C;  4OIO A;  3I4M K;  4A3J C;  3S1Q C;  3HOX K;  3S1Q K;  2VUM K;  3EQL A;  4C2M C;  2NVT C;  3DXJ A;  5IYB C;  2WB1 L;  5IYB K;  4A3M C;  4A3M K;  3S1M K;  3FKI C;  1IW7 A;  4G7Z A;  3GTK C;  3RZO C;  3RZO K;  3WOD A;  1XPP A;  5C44 K;  3S17 C;  2NVQ C;  3M4O C;  5IP7 K;  4LK1 A;  4Y7N C;  1SFO C;  2NVQ K;  1SFO K;  3M3Y C;  2NVY C;  4QIW L;  3HOU K;  4MEY A;  2NVY K;  3CQZ C;  4MQ9 A;  2JA5 C;  2PA8 L;  3CQZ K;  3M3Y K;  3GTG C;  1TWH C;  4QJV A;  3S15 C;  1TWH K;  3GTG K;  3S15 K;  5D4D A;  4AYB D;  3K7A C;  4QJV B;  2JA8 C;  4BXX C;  3K7A K;  2JA8 K;  4BY1 C;  4BXX K;  3RZD K;  3GTQ K;  4Q5S A;  2A68 A;  4BY7 C;  2PMZ L;  2WB1 D;  3PO2 C;  3HOX C;  1R9T C;  4C3J C;  3PO2 K;  2VUM C;  4A3K K;  2A6H A;  4C3J K;  1R9T K;  4BY7 K;  2E2J C;  4BBR K;  5M3F K;  1Y1V C;  2E2J K;  5C4J C;  1Y1V K;  4NOI A;  2A6E A;  5C4J K;  5C4X C;  5C4X K;  2JA7 C;  5FJ8 K;  2JA7 K;  2R7Z C;  2A69 A;  3I4N C;  2R7Z K;  4YFN A;  3GTL C;  3GTM K;  4QIW D;  3GTL K;  3S14 K;  5C44 C;  3HKZ D;  5FLM C;  1SMY A;  4C3H C;  5IP7 C;  4Q4Z A;  3GTM C;  3S2D C;  4XSX A;  4C3H K;  5FLM K;  3S2D K;  3HOU C;  5IP9 C;  3I4N K;  5IP9 K;  1K83 K;  2E2I C;  2E2I K;  4A3D C;  4OIR A;  3S17 K;  4A3D K;  2Y0S L;  4G7O A;  4LJZ A;  4XLP A;  4OIQ A;  3H3V L;  3RZD C;  3GTQ C;  4A3B C;  3S1M C;  5C3E C;  5C3E K;  1TWF C; 
#chains in the Genus database with same CATH topology
 4FZB A;  4YFX A;  4C3I C;  4C3I K;  4ZH4 A;  3GTJ A;  1TWA C;  1TWA K;  3S14 C;  3GTO C;  3GTO K;  4ILD A;  1ZYR A;  1YNN A;  2XCR B;  2B63 K;  4A3G C;  1K83 C;  4A3G K;  4Y52 C;  4KMH A;  4Y52 K;  2R93 A;  2NVX A;  1WQH A;  3S0X A;  4WJ4 A;  3GTP C;  3FOE A;  2E2H A;  1TWC A;  3GTP K;  4JK1 A;  1I3Q A;  4KB4 A;  3HOY C;  5M5Y K;  1I50 A;  3HOY K;  4A3F C;  3A8K A;  4OIP A;  4A3F K;  1C0A A;  1WOO A;  3HOV C;  5HL8 A;  3HOV K;  3HKZ L;  5JVO A;  3PO3 C;  4BKW A;  3PO3 K;  1TWG A;  3S2H C;  2JA6 C;  3S2H K;  1J6V A;  1F7V A;  3OEP A;  3H0G A;  4WF9 S;  5HL7 S;  4GT9 A;  4BY1 K;  3AD7 C;  1VJE A;  5HQH A;  3DXJ A;  3TTG A;  1DCH A;  3N3Y A;  3FKI C;  2P5M A;  3GDZ A;  4GTB A;  2EBB A;  3S17 C;  2CFA B;  5IP7 K;  3S17 K;  1O28 A;  1TWH C;  2ZFZ A;  1TWH K;  1WQG A;  5E68 A;  3K7A C;  3K7A K;  3GEE A;  5TJ3 A;  1IS1 A;  1VRQ C;  2WB1 D;  1R9T C;  1R9T K;  4LOW A;  1WOS A;  1Y1V C;  1Y1V K;  4BLB A;  2A6E A;  3PIO S;  4KM9 A;  5FJ8 K;  1SFO A;  4KB2 A;  2A69 A;  1B4B A;  5C44 C;  1WSR A;  3N0B A;  1VLO A;  5FLM C;  1SMY A;  2V6T A;  4Q4Z A;  5FLM K;  3ERE D;  3HOU C;  2V6U A;  4KDD A;  4G7O A;  4LJZ A;  3LAP A;  3RZD C;  4PAB A;  3I4N C;  3I4N K;  2GSN A;  4KMA A;  1RU0 A;  4GTL A;  4LLG A;  4WFB S;  2R93 K;  2KXY A;  3PIP S;  3Q3Q A;  1TWC C;  2R92 C;  1WCM A;  1TWC K;  2R92 K;  5CJ9 A;  1I3Q K;  1DCP A;  1ZQ1 C;  5IYC C;  5IYC K;  4GZY A;  5M5W K;  2ZJQ S;  2WAQ L;  4G7H A;  1TWG C;  1JOE A;  4LK0 A;  1TWG K;  3A8I A;  4A3J K;  3H0G C;  2NVT K;  4XCH A;  5TMC A;  3H0G K;  1XZQ A;  1YNJ A;  4A3C C;  4GTE A;  5IOT A;  5TMF A;  4A3C K;  1BJT A;  3GEI A;  4GTF A;  1UV7 A;  1B4A A;  1F93 A;  1DD5 A;  1BS2 A;  1WSV A;  1Y1W C;  2B63 C;  3OPF A;  2L5N A;  1Y1W K;  1BDF A;  3HOZ C;  1VH2 A;  3H3V D;  2YU9 C;  1O26 A;  3HOZ K;  2YU9 K;  3HOX K;  4KMD A;  2GSO A;  1O29 A;  3GTK A;  5IYB C;  1ZXO A;  1WIH A;  5IYB K;  4A3M C;  4BLA A;  4A3M K;  1INN A;  1O24 A;  2NVY A;  5EGH A;  3HXA A;  3CQZ A;  2JA5 A;  3RZO C;  1XZP A;  2ZUF A;  3RZO K;  3WOD A;  1SFO C;  1IQ0 A;  1SFO K;  3GIR A;  3GTG C;  4QJV A;  1HI9 A;  1ZVU A;  3GTG K;  4IO9 S;  2VUM A;  4AYB D;  4C45 A;  4BY1 C;  1EFW A;  4Q5S A;  4IOA S;  3QX3 A;  4IOC S;  4C3J C;  4A3K K;  4C3J K;  3VA7 A;  2R7Z A;  2E2J C;  4BBR K;  2E2J K;  5C4J C;  1J6X A;  5C4J K;  3GTM A;  5C4X C;  2JH3 A;  5C4X K;  3BP3 A;  4M1X A;  4QIW D;  2E2I A;  4C3H C;  5IP7 C;  4C3H K;  4XSX A;  4GTC A;  5IP9 C;  1JQW A;  5IP9 K;  3CAG A;  3GTQ A;  3AD9 C;  5DM6 S;  1J6W A;  2KPU A;  4OIR A;  1KQ4 A;  4KC6 A;  2ZJR S;  4OIQ A;  3H3V L;  3AQO A;  4A3B C;  4U67 S;  5C3E C;  4A3B K;  1WQF A;  5C3E K;  1TWF C;  4P9S A;  4WFA S;  2BE5 A;  1TWF K;  4YFK A;  1TWA A;  3JST A;  4KAT A;  3TFI A;  3GTL A;  3S16 C;  4LR2 A;  5IYD C;  4MEX A;  3S16 K;  4BBS K;  1PJ6 A;  5IYD K;  2O5J A;  5DM7 S;  1K83 A;  3L4K A;  1O2B A;  1YX2 A;  3GTJ C;  2ZJP S;  3GTJ K;  4KM8 A;  5JFE A;  3GTP A;  4OIN A;  2D6F C;  4AYB L;  1FEU A;  4KAS A;  4C2M K;  4A3E C;  5M3M K;  3T00 A;  4A3E K;  3ORE A;  2R93 C;  2NVX C;  1O27 A;  3N0C A;  2NVX K;  4A3I C;  2ZUE A;  1WOP A;  2E2H C;  4A3I K;  3GTK K;  2E2H K;  1I3Q C;  4G0V A;  3GEH A;  2JA6 A;  5IOS A;  4GTD A;  2P8T A;  4Y7N K;  4LQY A;  4XLN A;  4GFQ A;  1IBA A;  2JA5 K;  1I50 C;  2CW0 A;  1I50 K;  4A93 C;  1ZBS A;  1XXA A;  4A93 K;  2Y0S D;  1O2A A;  1BGW A;  2RH6 A;  5M5X K;  1F7U A;  2O5I A;  4WIL A;  5IOQ A;  3MML B;  3I4M C;  4OIO A;  3I4M K;  3FKI A;  4A3J C;  4DDQ A;  2VUM K;  2NVT C;  2WB1 L;  1XXC A;  1O25 A;  2KQ1 A;  1PJ5 A;  4G7Z A;  1TWH A;  1JVI A;  2GAH C;  4PAA A;  1X31 C;  3M4O C;  3GTM K;  3M4O K;  1EI6 A;  4WFN S;  1EK8 A;  3M3Y C;  1XZP B;  4MEY A;  2RGR A;  3M3Y K;  2Y3P A;  1O2F B;  5D4D A;  3LPX A;  1R9T A;  4QJV B;  3TFH A;  2JA8 C;  2JA8 K;  3GSI A;  4KAW X;  3GTQ K;  2A68 A;  3HOX C;  3SZZ A;  2A6H A;  1USO A;  5M3F K;  5CHP A;  3AQP A;  1G51 A;  4G0W A;  4YFN A;  3GTL C;  3FHZ A;  4G0U A;  3GTL K;  3S14 K;  1PJ7 A;  2FQT A;  3G4A A;  1K83 K;  3T02 A;  2Y0S L;  5L46 A;  3LAJ A;  1ISE A;  2R92 A;  3S1R C;  2JA7 A;  4A3K C;  3S1R K;  4BBR C;  5EGE A;  1XXB A;  1HQM A;  3CF5 S;  3G4C A;  1EQR A;  2XCO A;  1I6V A;  1GE9 A;  1WOR A;  3S1N C;  3S1N K;  3T01 A;  2PA8 D;  1WCM C;  3BP8 C;  2XCQ A;  1WCM K;  3V4G A;  2JA6 K;  5JVG S;  2PMZ D;  4A3L C;  4A3L K;  1DCO A;  5IOR A;  4RMF A;  2KWA A;  3NUH A;  2W7V A;  2V6S A;  4XSZ A;  3FKI K;  4BBS C;  4X6A C;  3GTO A;  4X6A K;  3AD8 C;  1I6H C;  1EH1 A;  1Y1W A;  3LYW A;  1I6H K;  2B63 A;  2YU9 A;  4P5A A;  4GTA A;  2WAQ D;  5JVH S;  3HOW C;  4AH6 A;  3BUE A;  3HOW K;  2PHC B;  4KN4 A;  4KN7 A;  4KMU A;  1YCL A;  1J98 A;  2PPB A;  4YG2 A;  4FM9 A;  2FQO A;  3S1Q C;  3S1Q K;  3EQL A;  4C2M C;  3L4J A;  1IL2 A;  3AH5 A;  4WCE S;  1IW7 A;  1VGX A;  2CFA A;  3FOF A;  2GAG C;  3GTG A;  3GTK C;  1XPP A;  5C44 K;  1XZQ B;  3TFJ A;  2NVQ C;  4LK1 A;  4Y7N C;  2NVQ K;  2NVY C;  4QIW L;  4J3N A;  3HOU K;  2NVY K;  3CQZ C;  4MQ9 A;  2JA5 C;  2PA8 L;  3A8J A;  3CQZ K;  4WJ3 M;  1AB4 A;  4P5B A;  3S15 C;  3S15 K;  1IE0 A;  4BXX C;  4BXX K;  3RZD K;  3SZY A;  4BY7 C;  2PMZ L;  3PO2 C;  4BY7 K;  4O2D A;  3PO2 K;  2VUM C;  4NOI A;  4KAR A;  2JA7 C;  3ADA C;  2L3U A;  2JA7 K;  2R7Z C;  2GSU A;  2R7Z K;  3HKZ D;  3GTM C;  3S2D C;  3S2D K;  1USM A;  1V5V A;  2E2I C;  2E2I K;  3DLL S;  3IPJ A;  4A3D C;  1TWF A;  4A3D K;  4XLP A;  1F9N A;  1Y1V A;  3GTQ C;  3S1M C;  3S1M K;  1L0W A; 
#chains in the Genus database with same CATH homology
 4A3K C;  1TWF K;  2BE5 A;  3S1R K;  4YFK A;  4BBR C;  1HQM A;  4LLG A;  4C3I C;  4YFX A;  3S16 C;  5IYD C;  4MEX A;  4C3I K;  1I6V A;  3S16 K;  4ZH4 A;  4BBS K;  2R93 K;  5IYD K;  1TWC C;  2R92 C;  3S1N C;  1TWC K;  2R92 K;  1TWA C;  2O5J A;  3S1N K;  1I3Q K;  1TWA K;  3S14 C;  3GTO C;  3GTO K;  1ZYR A;  2PA8 D;  3GTJ C;  5IYC C;  3M4O K;  1YNN A;  3GTJ K;  5IYC K;  1WCM C;  4GZY A;  1WCM K;  5M5W K;  2JA6 K;  2B63 K;  4A3G C;  1K83 C;  2WAQ L;  4A3G K;  4Y52 C;  4G7H A;  4OIN A;  4Y52 K;  1TWG C;  4LK0 A;  1TWG K;  2PMZ D;  4A3L C;  4AYB L;  4A3L K;  4A3J K;  4C2M K;  4A3E C;  3H0G C;  5M3M K;  2NVT K;  5TMC A;  3GTP C;  3H0G K;  4A3E K;  3GTP K;  4JK1 A;  4XSZ A;  1YNJ A;  4A3C C;  2R93 C;  2NVX C;  4BBS C;  5TMF A;  4X6A C;  3FKI K;  2NVX K;  3HOY C;  5M5Y K;  4A3C K;  4X6A K;  4A3I C;  3HOY K;  4A3F C;  2E2H C;  4A3I K;  4OIP A;  4A3F K;  2E2H K;  3GTK K;  1I3Q C;  1I6H C;  3HOV C;  1I6H K;  3HOV K;  4Y7N K;  4A3B K;  4XLN A;  3HKZ L;  3PO3 C;  2JA5 K;  1I50 C;  2CW0 A;  2WAQ D;  3PO3 K;  1I50 K;  4A93 C;  3S2H C;  4A93 K;  2JA6 C;  1Y1W C;  2Y0S D;  2B63 C;  3HOW C;  1Y1W K;  3S2H K;  3HOW K;  1BDF A;  3HOZ C;  4KN4 A;  3H3V D;  5M5X K;  2YU9 C;  4KN7 A;  3S1R C;  2O5I A;  2YU9 K;  4KMU A;  4BY1 K;  3HOZ K;  2PPB A;  4YG2 A;  3I4M C;  4OIO A;  3I4M K;  4A3J C;  3S1Q C;  3HOX K;  3S1Q K;  2VUM K;  3EQL A;  4C2M C;  2NVT C;  3DXJ A;  5IYB C;  2WB1 L;  5IYB K;  4A3M C;  4A3M K;  3S1M K;  3FKI C;  1IW7 A;  4G7Z A;  3GTK C;  3RZO C;  3RZO K;  3WOD A;  1XPP A;  5C44 K;  3S17 C;  2NVQ C;  3M4O C;  5IP7 K;  4LK1 A;  4Y7N C;  1SFO C;  2NVQ K;  1SFO K;  3M3Y C;  2NVY C;  4QIW L;  3HOU K;  4MEY A;  2NVY K;  3CQZ C;  4MQ9 A;  2JA5 C;  2PA8 L;  3CQZ K;  3M3Y K;  3GTG C;  1TWH C;  4QJV A;  3S15 C;  1TWH K;  3GTG K;  3S15 K;  5D4D A;  4AYB D;  3K7A C;  4QJV B;  2JA8 C;  4BXX C;  3K7A K;  2JA8 K;  4BY1 C;  4BXX K;  3RZD K;  3GTQ K;  4Q5S A;  2A68 A;  4BY7 C;  2PMZ L;  2WB1 D;  3PO2 C;  3HOX C;  1R9T C;  4C3J C;  3PO2 K;  2VUM C;  4A3K K;  2A6H A;  4C3J K;  1R9T K;  4BY7 K;  2E2J C;  4BBR K;  5M3F K;  1Y1V C;  2E2J K;  5C4J C;  1Y1V K;  4NOI A;  2A6E A;  5C4J K;  5C4X C;  5C4X K;  2JA7 C;  5FJ8 K;  2JA7 K;  2R7Z C;  2A69 A;  3I4N C;  2R7Z K;  4YFN A;  3GTL C;  3GTM K;  4QIW D;  3GTL K;  3S14 K;  5C44 C;  3HKZ D;  5FLM C;  1SMY A;  4C3H C;  5IP7 C;  4Q4Z A;  3GTM C;  3S2D C;  4XSX A;  4C3H K;  5FLM K;  3S2D K;  3HOU C;  5IP9 C;  3I4N K;  5IP9 K;  1K83 K;  2E2I C;  2E2I K;  4A3D C;  4OIR A;  3S17 K;  4A3D K;  2Y0S L;  4G7O A;  4LJZ A;  4XLP A;  4OIQ A;  3H3V L;  3RZD C;  3GTQ C;  4A3B C;  3S1M C;  5C3E C;  5C3E K;  1TWF C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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