4XSXA

Crystal structure of cbr 703 bound to escherichia coli rna polymerase holoenzyme
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
b'FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase subunit alpha
publication title CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
pubmed doi rcsb
source organism Escherichia coli (strain k12)
molecule tags Transcription/antibiotic
total genus 42
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4xsxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4xsxA01
3S1RK 3HOZK 4XSXA 1TWGC 2NVXK 4XLPA 4Y7NC 3S1NC 1TWGK 4Y7NK 4BY1K 4C3HC 4A3KC 3S1NK 4C3HK 4A3KK 2NVYC 5IP7C 5C3EC 2NVYK 5C3EK 3S17C 3PO3C 5C4XK 3PO3K 2E2HC 2E2HK 1ZYRA 2A68A 5TMCA 1R9TC 4A3FC 1R9TK 3S1MC 4X6AC 3S1MK 4X6AK 4AYBD 1SFOC 3HOWC 5M5WK 1SFOK 2O5IA 3HOWK 4LLGA 4NOIA 4A3DC 4A3MC 4A3BC 4A3DK 3HOYK 4OIRA 4A3LK 2WB1D 2R7ZC 2R7ZK 3WODA 1YNNA 3I4MC 3I4MK 3CQZC 4LK1A 2A6HA 3HOUC 4G7HA 1Y1WC 5TMFA 2R92C 2JA6C 3CQZK 2E2IC 1Y1WK 4C3IC 2JA6K 2R92K 3S14C 4C3IK 4A3JC 2NVTC 5FJ8K 3HOXK 4A3JK 1WCMC 4AYBL 4KN4A 1WCMK 1HQMA 2NVTK 4MQ9A 5IYDC 4LJZA 2YU9C 1XPPA 2YU9K 5IYCC 2WB1L 5IYDK 3DXJA 3RZDC 4C2MC 3RZDK 5IP7K 4C2MK 3HOUK 1IW7A 3S17K 1SMYA 4YFKA 4XLNA 1TWCC 3HOVC 3HOVK 1I3QC 4YG2A 4A3FK 3GTGC 3GTKC 3GTOC 3GTGK 3GTKK 2Y0SD 4Y52C 1BDFA 4Y52K 2VUMC 4A3MK 2VUMK 4QIWD 4A3BK 5IYBC 2PA8D 2E2JC 2BE5A 5IYBK 2JA8C 5C4JC 2E2JK 2JA8K 2WAQD 3S1QK 2JA5C 4JK1A 4QJVA 4Q4ZA 3K7AC 4LK0A 2A69A 4A3EC 4G7OA 4A3CC 4A3LC 3GTMC 4Q5SA 4G7ZA 3K7AK 4MEXA 2E2IK 2JA5K 3GTMK 1Y1VC 1I6VA 3HKZD 2JA7C 1Y1VK 3S2DC 2Y0SL 2A6EA 5D4DA 2JA7K 3S2DK 1TWFC 1TWFK 4QIWL 2PA8L 5IYCK 1YNJA 3FKIC 3FKIK 4A3IC 1K83C 2WAQL 1K83K 3EQLA 4A3IK 4GZYA 4QJVB 1TWHC 1TWCK 1TWHK 1I3QK 3H0GC 4BY7C 3H0GK 3HKZL 4BY7K 3M4OC 5M5YK 3S2HC 3GTOK 3S2HK 4YFXA 4BBRC 4ZH4A 2PPBA 2B63C 2O5JA 2B63K 5C44C 3PO2C 2R93C 1I50C 5C44K 3PO2K 1I50K 4A3GC 2R93K 3S1RC 5C4JK 4A3GK 4KN7A 3HOZC 4BXXC 4BXXK 2NVXC 4A3EK 4BY1C 5M3MK 3I4NC 3I4NK 4OIQA 5C4XC 3GTQC 3S1QC 3H3VD 3GTQK 2CW0A 2PMZD 5IP9C 4C3JC 2NVQC 1I6HC 5IP9K 4C3JK 2NVQK 1I6HK 4YFNA 4OIOA 4OINA 3RZOC 3GTJC 3RZOK 1TWAC 3GTJK 3GTLC 1TWAK 3GTLK 5M5XK 4KMUA 3HOYC 3S15C 3S15K 5FLMC 3GTPC 2PMZL 5FLMK 4BBSC 3M3YC 3GTPK 3H3VL 3M3YK 3M4OK 3S14K 4A3CK 4BBSK 4A93C 4BBRK 3S16C 4A93K 3S16K 4MEYA 4XSZA 5M3FK 4OIPA 3HOXC
chains in the Genus database with same CATH superfamily
1WQGA 3ADAC 1VLOA 3Q3QA 4GTLA 3S1NC 3N0CA 3V4GA 4BY1K 1VJEA 4A3KK 2NVYC 5IP7C 5C3EC 3QX3A 3S17C 3H0GA 2W7VA 3GTOA 2KPUA 4C45A 4G0VA 1R9TC 3S1MK 4X6AK 4AYBD 4A3MC 2EBBA 1YNNA 3I4MC 2A6HA 3CQZK 4G7HA 2R92C 5TMFA 1Y1WK 2E2IC 3S14K 3HOXK 1J6VA 1WCMC 4FM9A 2NVTK 1HQMA 1IQ0A 4GTAA 5IYDC 1DCOA 5IYCC 1USMA 2P5MA 3RZDC 1O29A 5IP7K 1IW7A 3S17K 1SMYA 2V6SA 4XLNA 3HOVC 5DM6S 1JQWA 3GTGC 2R93A 4KMHA 5CHPA 4Y52C 2KQ1A 3T02A 1F7UA 3GIRA 1DCHA 4A3MK 4QIWD 4WFBS 4LR2A 2VUMK 2PA8D 5IYBK 1INNA 2E2JK 5HQHA 2WAQD 4QJVA 3K7AC 4A3EC 4IO9S 5JFEA 4G7ZA 2E2IK 3GTMK 1Y1VK 2Y0SL 3S2DK 1TWFK 1TWAA 1WSVA 5IYCK 1F93A 3FKIK 4A3IK 1K83K 3EQLA 4GZYA 1F9NA 4QJVB 1TWHC 3H0GC 1Y1WA 1ZQ1C 3S2HK 4YFXA 3LAPA 4BBRC 2B63C 2O5JA 5C44C 3AD7C 1I50K 3S1RC 2NVYA 5JVOA 4A3GK 3HOZC 4BXXC 3TFJA 4A3EK 1ISEA 1L0WA 3FOEA 4WJ4A 3I4NC 4WJ3M 3MMLB 1EK8A 3GTQC 2CW0A 1I6HC 1R9TA 2NVQK 4C3JK 4OIOA 4WFAS 3G4AA 3RZOK 3HOYC 1J6XA 3H3VL 2R92A 2E2IA 4A93C 4BBRK 3S16C 1FEUA 3GEEA 1XZPA 1TWFA 1XZQB 4OIPA 3G4CA 1EQRA 3S1RK 3HOZK 1K83A 1IS1A 4XLPA 1WSRA 4A3KC 3AH5A 1BS2A 1PJ5A 3PO3K 2E2HK 3GTGA 1WQHA 1XZPB 1G51A 3S1MC 4X6AC 1I50A 5M5WK 1O24A 2O5IA 4LLGA 1YX2A 4A3BC 4A3DK 3HOYK 1O26A 3WODA 2FQTA 3CQZC 1Y1WC 3S14C 4C3IK 2NVTC 4A3JK 1IL2A 4AYBL 4KN4A 2D6FC 4LJZA 2YU9K 1TWHA 3DXJA 3GSIA 2FQOA 4YFKA 5TJ3A 3L4KA 2Y3PA 2B63A 4G0UA 1BDFA 2VUMC 2ZFZA 4U67S 5L46A 4GT9A 4A3BK 1VRQC 5IYBC 2E2JC 2BE5A 1VH2A 2JA8K 4JK1A 4G7OA 2JA5K 3GTQA 4LK0A 4A3LK 4Q5SA 4A3CK 3GTMC 4MEXA 4KM9A 4LQYA 1Y1VC 3S2DC 1TWFC 4QIWL 1XXAA 2PA8L 3FKIC 4A3IC 1K83C 2WAQL 1DCPA 2ZJPS 3N3YA 4BY7K 1O2BA 3S2HC 4ZH4A 2PPBA 1HI9A 1USOA 1I50C 3PO2K 4A3GC 2GSUA 4KN7A 3S0XA 1O28A 5DM7S 4OIQA 5C4XC 4P5BA 2PMZD 2NVQC 3T01A 4C3JC 3S1QK 5IP9K 2XCQA 4WILA 3RZOC 3GTJK 3GTLK 2JA5A 3CQZA 3S15K 3M3YK 3AQPA 3GDZA 2ZJQS 4DDQA 1JVIA 3GEHA 5HL7S 5M3FK 4RMFA 1O2AA 4GTDA 4XSXA 1TWGK 4Y7NK 4BKWA 4KM8A 1J98A 4C3HK 4BLBA 1WIHA 1B4BA 3PO3C 3OREA 5C4XK 3OEPA 5IORA 4XCHA 2E2HC 3BUEA 1ZYRA 1XXBA 3LAJA 3ERED 2ZUEA 1XZQA 5E68A 5TMCA 3TTGA 5IOTA 2VUMA 1UV7A 2GAHC 1SFOK 3HOWK 4NOIA 4A3DC 4WF9S 4KB2A 2GSOA 3CAGA 2WB1D 3GTMA 1DD5A 2R7ZK 1Y1VA 5JVHS 5JVGS 4LK1A 3HOUC 2ZUFA 4M1XA 4WCES 2JA6K 4C3IC 3HXAA 3TFHA 4A3JC 4P9SA 3FKIA 1ZVUA 1XXCA 4MQ9A 2YU9C 4ILDA 3GTJA 4GTBA 2V6UA 4C2MK 1WORA 3PIPS 1TWCC 1I3QC 4KB4A 4IOCS 2PHCB 4KDDA 3GTKK 3OPFA 1O25A 2JA8C 5C4JC 2JA5C 3BP3A 4A3LC 4A3CC 1O27A 1EFWA 3HOUK 1YCLA 4J3NA 4KC6A 2RGRA 1I6VA 3HKZD 3T00A 2JA7K 2A6EA 5D4DA 1BJTA 3FOFA 3A8JA 4KAWX 4KATA 5CJ9A 1TWCK 4GFQA 3VA7A 1I3QK 4BY7C 4KASA 4GTFA 4LOWA 4O2DA 3PO2C 2R93K 3AQOA 5C4JK 1WOPA 5IOQA 2L3UA 2NVXC 2E2HA 4GTEA 3CF5S 3L4JA 5M3MK 3S1QC 4IOAS 2V6TA 5IP9C 5EGHA 4YFNA 5HL8A 3GTKA 4OINA 3A8IA 3TFIA 1BGWA 3GTJC 3GTLC 1TWAK 3PIOS 5M5XK 3S15C 1ZBSA 2PMZL 5FLMK 3M3YC 3GTPK 4BBSK 4KARA 5IOSA 2JA7A 1V5VA 4MEYA 4XSZA 2YU9A 1XPPA 1F7VA 3DLLS 1TWGC 2NVXK 4Y7NC 3S1NK 4C3HC 1TWCA 2NVYK 5C3EK 1I3QA 2KWAA 4PABA 2A68A 2JH3A 4A3FC 1R9TK 1EH1A 3N0BA 1PJ6A 1SFOC 3HOWC 3FHZA 4OIRA 4BLAA 2R7ZC 2XCOA 3A8KA 3I4MK 4KMAA 2JA6C 2R92K 2L5NA 5FJ8K 1C0AA 1WCMK 4GTCA 4KMDA 2GAGC 5IYDK 2WB1L 4C2MC 3RZDK 3SZZA 3GTPA 1O2FB 2P8TA 4PAAA 3HOVK 4YG2A 4A3FK 3GTKC 3GTOC 3GTGK 2Y0SD 2KXYA 4Y52K 1IE0A 3IPJA 2NVXA 1WOOA 2CFAA 4WFNS 1PJ7A 4Q4ZA 2A69A 3K7AK 1GE9A 1B4AA 1JOEA 2XCRB 2JA7C 5EGEA 1VGXA 1IBAA 3GTLA 1YNJA 2CFAB 4P5AA 1TWHK 3H0GK 3HKZL 3LPXA 4G0WA 1J6WA 3M4OC 5M5YK 3GTOK 1WCMA 1AB4A 2B63K 3JSTA 1WOSA 1TWGA 1KQ4A 2R93C 2RH6A 5C44K 4BXXK 4FZBA 4AH6A 4BY1C 3BP8C 1EI6A 1RU0A 3AD9C 3I4NK 1WQFA 3H3VD 3GTQK 1I6HK 3AD8C 1SFOA 1ZXOA 1TWAC 3LYWA 2R7ZA 3SZYA 1X31C 3NUHA 4KMUA 3GEIA 5FLMC 3GTPC 2JA6A 4BBSC 3M4OK 4A93K 3S16K 2ZJRS 2GSNA 3HOXC
chains in the Genus database with same CATH topology
3S1RK 3HOZK 4XSXA 1TWGC 2NVXK 4XLPA 4Y7NC 3S1NC 1TWGK 4Y7NK 4BY1K 4C3HC 4A3KC 3S1NK 4C3HK 4A3KK 2NVYC 5IP7C 5C3EC 2NVYK 5C3EK 3S17C 3PO3C 5C4XK 3PO3K 2E2HC 2E2HK 1ZYRA 2A68A 5TMCA 1R9TC 4A3FC 1R9TK 3S1MC 4X6AC 3S1MK 4X6AK 4AYBD 1SFOC 3HOWC 5M5WK 1SFOK 2O5IA 3HOWK 4LLGA 4NOIA 4A3DC 4A3MC 4A3BC 4A3DK 3HOYK 4OIRA 4A3LK 2WB1D 2R7ZC 2R7ZK 3WODA 1YNNA 3I4MC 3I4MK 3CQZC 4LK1A 2A6HA 3HOUC 4G7HA 1Y1WC 5TMFA 2R92C 2JA6C 3CQZK 2E2IC 1Y1WK 4C3IC 2JA6K 2R92K 3S14C 4C3IK 4A3JC 2NVTC 5FJ8K 3HOXK 4A3JK 1WCMC 4AYBL 4KN4A 1WCMK 1HQMA 2NVTK 4MQ9A 5IYDC 4LJZA 2YU9C 1XPPA 2YU9K 5IYCC 2WB1L 5IYDK 3DXJA 3RZDC 4C2MC 3RZDK 5IP7K 4C2MK 3HOUK 1IW7A 3S17K 1SMYA 4YFKA 4XLNA 1TWCC 3HOVC 3HOVK 1I3QC 4YG2A 4A3FK 3GTGC 3GTKC 3GTOC 3GTGK 3GTKK 2Y0SD 4Y52C 1BDFA 4Y52K 2VUMC 4A3MK 2VUMK 4QIWD 4A3BK 5IYBC 2PA8D 2E2JC 2BE5A 5IYBK 2JA8C 5C4JC 2E2JK 2JA8K 2WAQD 3S1QK 2JA5C 4JK1A 4QJVA 4Q4ZA 3K7AC 4LK0A 2A69A 4A3EC 4G7OA 4A3CC 4A3LC 3GTMC 4Q5SA 4G7ZA 3K7AK 4MEXA 2E2IK 2JA5K 3GTMK 1Y1VC 1I6VA 3HKZD 2JA7C 1Y1VK 3S2DC 2Y0SL 2A6EA 5D4DA 2JA7K 3S2DK 1TWFC 1TWFK 4QIWL 2PA8L 5IYCK 1YNJA 3FKIC 3FKIK 4A3IC 1K83C 2WAQL 1K83K 3EQLA 4A3IK 4GZYA 4QJVB 1TWHC 1TWCK 1TWHK 1I3QK 3H0GC 4BY7C 3H0GK 3HKZL 4BY7K 3M4OC 5M5YK 3S2HC 3GTOK 3S2HK 4YFXA 4BBRC 4ZH4A 2PPBA 2B63C 2O5JA 2B63K 5C44C 3PO2C 2R93C 1I50C 5C44K 3PO2K 1I50K 4A3GC 2R93K 3S1RC 5C4JK 4A3GK 4KN7A 3HOZC 4BXXC 4BXXK 2NVXC 4A3EK 4BY1C 5M3MK 3I4NC 3I4NK 4OIQA 5C4XC 3GTQC 3S1QC 3H3VD 3GTQK 2CW0A 2PMZD 5IP9C 4C3JC 2NVQC 1I6HC 5IP9K 4C3JK 2NVQK 1I6HK 4YFNA 4OIOA 4OINA 3RZOC 3GTJC 3RZOK 1TWAC 3GTJK 3GTLC 1TWAK 3GTLK 5M5XK 4KMUA 3HOYC 3S15C 3S15K 5FLMC 3GTPC 2PMZL 5FLMK 4BBSC 3M3YC 3GTPK 3H3VL 3M3YK 3M4OK 3S14K 4A3CK 4BBSK 4A93C 4BBRK 3S16C 4A93K 3S16K 4MEYA 4XSZA 5M3FK 4OIPA 3HOXC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1R K;  3HOZ K;  4XSX A;  1TWG C;  2NVX K;  4XLP A;  4Y7N C;  3S1N C;  1TWG K;  4Y7N K;  4BY1 K;  4C3H C;  4A3K C;  3S1N K;  4C3H K;  4A3K K;  2NVY C;  5IP7 C;  5C3E C;  2NVY K;  5C3E K;  3S17 C;  3PO3 C;  5C4X K;  3PO3 K;  2E2H C;  2E2H K;  1ZYR A;  2A68 A;  5TMC A;  1R9T C;  4A3F C;  1R9T K;  3S1M C;  4X6A C;  3S1M K;  4X6A K;  4AYB D;  1SFO C;  3HOW C;  5M5W K;  1SFO K;  2O5I A;  3HOW K;  4LLG A;  4NOI A;  4A3D C;  4A3M C;  4A3B C;  4A3D K;  3HOY K;  4OIR A;  4A3L K;  2WB1 D;  2R7Z C;  2R7Z K;  3WOD A;  1YNN A;  3I4M C;  3I4M K;  3CQZ C;  4LK1 A;  2A6H A;  3HOU C;  4G7H A;  1Y1W C;  5TMF A;  2R92 C;  2JA6 C;  3CQZ K;  2E2I C;  1Y1W K;  4C3I C;  2JA6 K;  2R92 K;  3S14 C;  4C3I K;  4A3J C;  2NVT C;  5FJ8 K;  3HOX K;  4A3J K;  1WCM C;  4AYB L;  4KN4 A;  1WCM K;  1HQM A;  2NVT K;  4MQ9 A;  5IYD C;  4LJZ A;  2YU9 C;  1XPP A;  2YU9 K;  5IYC C;  2WB1 L;  5IYD K;  3DXJ A;  3RZD C;  4C2M C;  3RZD K;  5IP7 K;  4C2M K;  3HOU K;  1IW7 A;  3S17 K;  1SMY A;  4YFK A;  4XLN A;  1TWC C;  3HOV C;  3HOV K;  1I3Q C;  4YG2 A;  4A3F K;  3GTG C;  3GTK C;  3GTO C;  3GTG K;  3GTK K;  2Y0S D;  4Y52 C;  1BDF A;  4Y52 K;  2VUM C;  4A3M K;  2VUM K;  4QIW D;  4A3B K;  5IYB C;  2PA8 D;  2E2J C;  2BE5 A;  5IYB K;  2JA8 C;  5C4J C;  2E2J K;  2JA8 K;  2WAQ D;  3S1Q K;  2JA5 C;  4JK1 A;  4QJV A;  4Q4Z A;  3K7A C;  4LK0 A;  2A69 A;  4A3E C;  4G7O A;  4A3C C;  4A3L C;  3GTM C;  4Q5S A;  4G7Z A;  3K7A K;  4MEX A;  2E2I K;  2JA5 K;  3GTM K;  1Y1V C;  1I6V A;  3HKZ D;  2JA7 C;  1Y1V K;  3S2D C;  2Y0S L;  2A6E A;  5D4D A;  2JA7 K;  3S2D K;  1TWF C;  1TWF K;  4QIW L;  2PA8 L;  5IYC K;  1YNJ A;  3FKI C;  3FKI K;  4A3I C;  1K83 C;  2WAQ L;  1K83 K;  3EQL A;  4A3I K;  4GZY A;  4QJV B;  1TWH C;  1TWC K;  1TWH K;  1I3Q K;  3H0G C;  4BY7 C;  3H0G K;  3HKZ L;  4BY7 K;  3M4O C;  5M5Y K;  3S2H C;  3GTO K;  3S2H K;  4YFX A;  4BBR C;  4ZH4 A;  2PPB A;  2B63 C;  2O5J A;  2B63 K;  5C44 C;  3PO2 C;  2R93 C;  1I50 C;  5C44 K;  3PO2 K;  1I50 K;  4A3G C;  2R93 K;  3S1R C;  5C4J K;  4A3G K;  4KN7 A;  3HOZ C;  4BXX C;  4BXX K;  2NVX C;  4A3E K;  4BY1 C;  5M3M K;  3I4N C;  3I4N K;  4OIQ A;  5C4X C;  3GTQ C;  3S1Q C;  3H3V D;  3GTQ K;  2CW0 A;  2PMZ D;  5IP9 C;  4C3J C;  2NVQ C;  1I6H C;  5IP9 K;  4C3J K;  2NVQ K;  1I6H K;  4YFN A;  4OIO A;  4OIN A;  3RZO C;  3GTJ C;  3RZO K;  1TWA C;  3GTJ K;  3GTL C;  1TWA K;  3GTL K;  5M5X K;  4KMU A;  3HOY C;  3S15 C;  3S15 K;  5FLM C;  3GTP C;  2PMZ L;  5FLM K;  4BBS C;  3M3Y C;  3GTP K;  3H3V L;  3M3Y K;  3M4O K;  3S14 K;  4A3C K;  4BBS K;  4A93 C;  4BBR K;  3S16 C;  4A93 K;  3S16 K;  4MEY A;  4XSZ A;  5M3F K;  4OIP A;  3HOX C; 
#chains in the Genus database with same CATH topology
 1WQG A;  3ADA C;  1VLO A;  3Q3Q A;  4GTL A;  3S1N C;  3N0C A;  3V4G A;  4BY1 K;  1VJE A;  4A3K K;  2NVY C;  5IP7 C;  5C3E C;  3QX3 A;  3S17 C;  3H0G A;  2W7V A;  3GTO A;  2KPU A;  4C45 A;  4G0V A;  1R9T C;  3S1M K;  4X6A K;  4AYB D;  4A3M C;  2EBB A;  1YNN A;  3I4M C;  2A6H A;  3CQZ K;  4G7H A;  2R92 C;  5TMF A;  1Y1W K;  2E2I C;  3S14 K;  3HOX K;  1J6V A;  1WCM C;  4FM9 A;  2NVT K;  1HQM A;  1IQ0 A;  4GTA A;  5IYD C;  1DCO A;  5IYC C;  1USM A;  2P5M A;  3RZD C;  1O29 A;  5IP7 K;  1IW7 A;  3S17 K;  1SMY A;  2V6S A;  4XLN A;  3HOV C;  5DM6 S;  1JQW A;  3GTG C;  2R93 A;  4KMH A;  5CHP A;  4Y52 C;  2KQ1 A;  3T02 A;  1F7U A;  3GIR A;  1DCH A;  4A3M K;  4QIW D;  4WFB S;  4LR2 A;  2VUM K;  2PA8 D;  5IYB K;  1INN A;  2E2J K;  5HQH A;  2WAQ D;  4QJV A;  3K7A C;  4A3E C;  4IO9 S;  5JFE A;  4G7Z A;  2E2I K;  3GTM K;  1Y1V K;  2Y0S L;  3S2D K;  1TWF K;  1TWA A;  1WSV A;  5IYC K;  1F93 A;  3FKI K;  4A3I K;  1K83 K;  3EQL A;  4GZY A;  1F9N A;  4QJV B;  1TWH C;  3H0G C;  1Y1W A;  1ZQ1 C;  3S2H K;  4YFX A;  3LAP A;  4BBR C;  2B63 C;  2O5J A;  5C44 C;  3AD7 C;  1I50 K;  3S1R C;  2NVY A;  5JVO A;  4A3G K;  3HOZ C;  4BXX C;  3TFJ A;  4A3E K;  1ISE A;  1L0W A;  3FOE A;  4WJ4 A;  3I4N C;  4WJ3 M;  3MML B;  1EK8 A;  3GTQ C;  2CW0 A;  1I6H C;  1R9T A;  2NVQ K;  4C3J K;  4OIO A;  4WFA S;  3G4A A;  3RZO K;  3HOY C;  1J6X A;  3H3V L;  2R92 A;  2E2I A;  4A93 C;  4BBR K;  3S16 C;  1FEU A;  3GEE A;  1XZP A;  1TWF A;  1XZQ B;  4OIP A;  3G4C A;  1EQR A;  3S1R K;  3HOZ K;  1K83 A;  1IS1 A;  4XLP A;  1WSR A;  4A3K C;  3AH5 A;  1BS2 A;  1PJ5 A;  3PO3 K;  2E2H K;  3GTG A;  1WQH A;  1XZP B;  1G51 A;  3S1M C;  4X6A C;  1I50 A;  5M5W K;  1O24 A;  2O5I A;  4LLG A;  1YX2 A;  4A3B C;  4A3D K;  3HOY K;  1O26 A;  3WOD A;  2FQT A;  3CQZ C;  1Y1W C;  3S14 C;  4C3I K;  2NVT C;  4A3J K;  1IL2 A;  4AYB L;  4KN4 A;  2D6F C;  4LJZ A;  2YU9 K;  1TWH A;  3DXJ A;  3GSI A;  2FQO A;  4YFK A;  5TJ3 A;  3L4K A;  2Y3P A;  2B63 A;  4G0U A;  1BDF A;  2VUM C;  2ZFZ A;  4U67 S;  5L46 A;  4GT9 A;  4A3B K;  1VRQ C;  5IYB C;  2E2J C;  2BE5 A;  1VH2 A;  2JA8 K;  4JK1 A;  4G7O A;  2JA5 K;  3GTQ A;  4LK0 A;  4A3L K;  4Q5S A;  4A3C K;  3GTM C;  4MEX A;  4KM9 A;  4LQY A;  1Y1V C;  3S2D C;  1TWF C;  4QIW L;  1XXA A;  2PA8 L;  3FKI C;  4A3I C;  1K83 C;  2WAQ L;  1DCP A;  2ZJP S;  3N3Y A;  4BY7 K;  1O2B A;  3S2H C;  4ZH4 A;  2PPB A;  1HI9 A;  1USO A;  1I50 C;  3PO2 K;  4A3G C;  2GSU A;  4KN7 A;  3S0X A;  1O28 A;  5DM7 S;  4OIQ A;  5C4X C;  4P5B A;  2PMZ D;  2NVQ C;  3T01 A;  4C3J C;  3S1Q K;  5IP9 K;  2XCQ A;  4WIL A;  3RZO C;  3GTJ K;  3GTL K;  2JA5 A;  3CQZ A;  3S15 K;  3M3Y K;  3AQP A;  3GDZ A;  2ZJQ S;  4DDQ A;  1JVI A;  3GEH A;  5HL7 S;  5M3F K;  4RMF A;  1O2A A;  4GTD A;  4XSX A;  1TWG K;  4Y7N K;  4BKW A;  4KM8 A;  1J98 A;  4C3H K;  4BLB A;  1WIH A;  1B4B A;  3PO3 C;  3ORE A;  5C4X K;  3OEP A;  5IOR A;  4XCH A;  2E2H C;  3BUE A;  1ZYR A;  1XXB A;  3LAJ A;  3ERE D;  2ZUE A;  1XZQ A;  5E68 A;  5TMC A;  3TTG A;  5IOT A;  2VUM A;  1UV7 A;  2GAH C;  1SFO K;  3HOW K;  4NOI A;  4A3D C;  4WF9 S;  4KB2 A;  2GSO A;  3CAG A;  2WB1 D;  3GTM A;  1DD5 A;  2R7Z K;  1Y1V A;  5JVH S;  5JVG S;  4LK1 A;  3HOU C;  2ZUF A;  4M1X A;  4WCE S;  2JA6 K;  4C3I C;  3HXA A;  3TFH A;  4A3J C;  4P9S A;  3FKI A;  1ZVU A;  1XXC A;  4MQ9 A;  2YU9 C;  4ILD A;  3GTJ A;  4GTB A;  2V6U A;  4C2M K;  1WOR A;  3PIP S;  1TWC C;  1I3Q C;  4KB4 A;  4IOC S;  2PHC B;  4KDD A;  3GTK K;  3OPF A;  1O25 A;  2JA8 C;  5C4J C;  2JA5 C;  3BP3 A;  4A3L C;  4A3C C;  1O27 A;  1EFW A;  3HOU K;  1YCL A;  4J3N A;  4KC6 A;  2RGR A;  1I6V A;  3HKZ D;  3T00 A;  2JA7 K;  2A6E A;  5D4D A;  1BJT A;  3FOF A;  3A8J A;  4KAW X;  4KAT A;  5CJ9 A;  1TWC K;  4GFQ A;  3VA7 A;  1I3Q K;  4BY7 C;  4KAS A;  4GTF A;  4LOW A;  4O2D A;  3PO2 C;  2R93 K;  3AQO A;  5C4J K;  1WOP A;  5IOQ A;  2L3U A;  2NVX C;  2E2H A;  4GTE A;  3CF5 S;  3L4J A;  5M3M K;  3S1Q C;  4IOA S;  2V6T A;  5IP9 C;  5EGH A;  4YFN A;  5HL8 A;  3GTK A;  4OIN A;  3A8I A;  3TFI A;  1BGW A;  3GTJ C;  3GTL C;  1TWA K;  3PIO S;  5M5X K;  3S15 C;  1ZBS A;  2PMZ L;  5FLM K;  3M3Y C;  3GTP K;  4BBS K;  4KAR A;  5IOS A;  2JA7 A;  1V5V A;  4MEY A;  4XSZ A;  2YU9 A;  1XPP A;  1F7V A;  3DLL S;  1TWG C;  2NVX K;  4Y7N C;  3S1N K;  4C3H C;  1TWC A;  2NVY K;  5C3E K;  1I3Q A;  2KWA A;  4PAB A;  2A68 A;  2JH3 A;  4A3F C;  1R9T K;  1EH1 A;  3N0B A;  1PJ6 A;  1SFO C;  3HOW C;  3FHZ A;  4OIR A;  4BLA A;  2R7Z C;  2XCO A;  3A8K A;  3I4M K;  4KMA A;  2JA6 C;  2R92 K;  2L5N A;  5FJ8 K;  1C0A A;  1WCM K;  4GTC A;  4KMD A;  2GAG C;  5IYD K;  2WB1 L;  4C2M C;  3RZD K;  3SZZ A;  3GTP A;  1O2F B;  2P8T A;  4PAA A;  3HOV K;  4YG2 A;  4A3F K;  3GTK C;  3GTO C;  3GTG K;  2Y0S D;  2KXY A;  4Y52 K;  1IE0 A;  3IPJ A;  2NVX A;  1WOO A;  2CFA A;  4WFN S;  1PJ7 A;  4Q4Z A;  2A69 A;  3K7A K;  1GE9 A;  1B4A A;  1JOE A;  2XCR B;  2JA7 C;  5EGE A;  1VGX A;  1IBA A;  3GTL A;  1YNJ A;  2CFA B;  4P5A A;  1TWH K;  3H0G K;  3HKZ L;  3LPX A;  4G0W A;  1J6W A;  3M4O C;  5M5Y K;  3GTO K;  1WCM A;  1AB4 A;  2B63 K;  3JST A;  1WOS A;  1TWG A;  1KQ4 A;  2R93 C;  2RH6 A;  5C44 K;  4BXX K;  4FZB A;  4AH6 A;  4BY1 C;  3BP8 C;  1EI6 A;  1RU0 A;  3AD9 C;  3I4N K;  1WQF A;  3H3V D;  3GTQ K;  1I6H K;  3AD8 C;  1SFO A;  1ZXO A;  1TWA C;  3LYW A;  2R7Z A;  3SZY A;  1X31 C;  3NUH A;  4KMU A;  3GEI A;  5FLM C;  3GTP C;  2JA6 A;  4BBS C;  3M4O K;  4A93 K;  3S16 K;  2ZJR S;  2GSN A;  3HOX C; 
#chains in the Genus database with same CATH homology
 3S1R K;  3HOZ K;  4XSX A;  1TWG C;  2NVX K;  4XLP A;  4Y7N C;  3S1N C;  1TWG K;  4Y7N K;  4BY1 K;  4C3H C;  4A3K C;  3S1N K;  4C3H K;  4A3K K;  2NVY C;  5IP7 C;  5C3E C;  2NVY K;  5C3E K;  3S17 C;  3PO3 C;  5C4X K;  3PO3 K;  2E2H C;  2E2H K;  1ZYR A;  2A68 A;  5TMC A;  1R9T C;  4A3F C;  1R9T K;  3S1M C;  4X6A C;  3S1M K;  4X6A K;  4AYB D;  1SFO C;  3HOW C;  5M5W K;  1SFO K;  2O5I A;  3HOW K;  4LLG A;  4NOI A;  4A3D C;  4A3M C;  4A3B C;  4A3D K;  3HOY K;  4OIR A;  4A3L K;  2WB1 D;  2R7Z C;  2R7Z K;  3WOD A;  1YNN A;  3I4M C;  3I4M K;  3CQZ C;  4LK1 A;  2A6H A;  3HOU C;  4G7H A;  1Y1W C;  5TMF A;  2R92 C;  2JA6 C;  3CQZ K;  2E2I C;  1Y1W K;  4C3I C;  2JA6 K;  2R92 K;  3S14 C;  4C3I K;  4A3J C;  2NVT C;  5FJ8 K;  3HOX K;  4A3J K;  1WCM C;  4AYB L;  4KN4 A;  1WCM K;  1HQM A;  2NVT K;  4MQ9 A;  5IYD C;  4LJZ A;  2YU9 C;  1XPP A;  2YU9 K;  5IYC C;  2WB1 L;  5IYD K;  3DXJ A;  3RZD C;  4C2M C;  3RZD K;  5IP7 K;  4C2M K;  3HOU K;  1IW7 A;  3S17 K;  1SMY A;  4YFK A;  4XLN A;  1TWC C;  3HOV C;  3HOV K;  1I3Q C;  4YG2 A;  4A3F K;  3GTG C;  3GTK C;  3GTO C;  3GTG K;  3GTK K;  2Y0S D;  4Y52 C;  1BDF A;  4Y52 K;  2VUM C;  4A3M K;  2VUM K;  4QIW D;  4A3B K;  5IYB C;  2PA8 D;  2E2J C;  2BE5 A;  5IYB K;  2JA8 C;  5C4J C;  2E2J K;  2JA8 K;  2WAQ D;  3S1Q K;  2JA5 C;  4JK1 A;  4QJV A;  4Q4Z A;  3K7A C;  4LK0 A;  2A69 A;  4A3E C;  4G7O A;  4A3C C;  4A3L C;  3GTM C;  4Q5S A;  4G7Z A;  3K7A K;  4MEX A;  2E2I K;  2JA5 K;  3GTM K;  1Y1V C;  1I6V A;  3HKZ D;  2JA7 C;  1Y1V K;  3S2D C;  2Y0S L;  2A6E A;  5D4D A;  2JA7 K;  3S2D K;  1TWF C;  1TWF K;  4QIW L;  2PA8 L;  5IYC K;  1YNJ A;  3FKI C;  3FKI K;  4A3I C;  1K83 C;  2WAQ L;  1K83 K;  3EQL A;  4A3I K;  4GZY A;  4QJV B;  1TWH C;  1TWC K;  1TWH K;  1I3Q K;  3H0G C;  4BY7 C;  3H0G K;  3HKZ L;  4BY7 K;  3M4O C;  5M5Y K;  3S2H C;  3GTO K;  3S2H K;  4YFX A;  4BBR C;  4ZH4 A;  2PPB A;  2B63 C;  2O5J A;  2B63 K;  5C44 C;  3PO2 C;  2R93 C;  1I50 C;  5C44 K;  3PO2 K;  1I50 K;  4A3G C;  2R93 K;  3S1R C;  5C4J K;  4A3G K;  4KN7 A;  3HOZ C;  4BXX C;  4BXX K;  2NVX C;  4A3E K;  4BY1 C;  5M3M K;  3I4N C;  3I4N K;  4OIQ A;  5C4X C;  3GTQ C;  3S1Q C;  3H3V D;  3GTQ K;  2CW0 A;  2PMZ D;  5IP9 C;  4C3J C;  2NVQ C;  1I6H C;  5IP9 K;  4C3J K;  2NVQ K;  1I6H K;  4YFN A;  4OIO A;  4OIN A;  3RZO C;  3GTJ C;  3RZO K;  1TWA C;  3GTJ K;  3GTL C;  1TWA K;  3GTL K;  5M5X K;  4KMU A;  3HOY C;  3S15 C;  3S15 K;  5FLM C;  3GTP C;  2PMZ L;  5FLM K;  4BBS C;  3M3Y C;  3GTP K;  3H3V L;  3M3Y K;  3M4O K;  3S14 K;  4A3C K;  4BBS K;  4A93 C;  4BBR K;  3S16 C;  4A93 K;  3S16 K;  4MEY A;  4XSZ A;  5M3F K;  4OIP A;  3HOX C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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