4XSXA

Crystal structure of cbr 703 bound to escherichia coli rna polymerase holoenzyme
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
pubmed doi rcsb
source organism Escherichia coli (strain k12)
molecule tags Transcription/antibiotic
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 42
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4xsxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4xsxA01
4A3LC 2NVYK 4BBRC 4C2MC 5IP9K 3H3VL 4XLNA 2R92C 3GTKC 4A3MC 1YNJA 3DXJA 3H3VD 1TWHK 3I4NC 4OIQA 3S14C 3S1QC 5FLMC 2WAQD 1I3QK 2NVXC 4BY7C 5D4DA 2WB1D 1IW7A 4C3IC 4AYBD 3HOZC 1TWGK 4Y52K 4C3IK 2Y0SL 1TWCC 4JK1A 3RZDK 2JA6C 5IYDK 4G7ZA 4A3IC 5C44K 3HOUK 4QJVA 4MQ9A 4C2MK 3HOYK 5TMFA 3I4NK 3RZOC 3PO3C 1HQMA 5IYBK 4A3MK 3HOXC 4BXXC 3S17K 3RZOK 4ZH4A 3I4MK 4KN4A 4A3DC 1Y1VK 4C3JK 4A3EK 5IYCC 3S17C 1Y1WK 4A3CC 4C3HK 3CQZC 3S1MC 3M3YC 5IYCK 3GTGC 4QIWD 4XSZA 3FKIC 2E2HK 2NVTC 3S1NC 3S15K 1I6HC 2NVQK 1TWFC 4BY1K 3GTOK 3GTJC 4G7OA 5FLMK 4A3GK 1K83C 4A3JC 4X6AC 2A68A 3M3YK 2PPBA 4OINA 1SFOC 2E2HC 3HOWC 3FKIK 5IP7C 2YU9C 3HKZL 4BBRK 3M4OK 4QJVB 1SFOK 3HOWK 3PO2K 3PO3K 2PA8L 1WCMK 5M3MK 4YFXA 4Q4ZA 2R93C 4YFKA 3GTPK 4BY1C 2JA8K 1K83K 1R9TC 2A69A 1XPPA 4A3JK 1YNNA 4LK1A 3S1RC 4A3BK 2PMZL 1TWGC 4Y52C 4A93C 3HOZK 3S2HK 3H0GK 2JA6K 2R7ZK 2JA7K 1TWCK 4KN7A 3S16K 2NVQC 2JA7C 4QIWL 5C4JC 2O5IA 4GZYA 2WAQL 4BY7K 3I4MC 4Y7NK 2WB1L 5TMCA 4C3HC 4A3CK 2BE5A 2CW0A 4OIOA 4A3GC 4MEXA 5M5WK 4BBSC 1SMYA 5C4XC 2E2JK 2VUMK 3GTLK 3WODA 5C3EC 5C4JK 5IP7K 2YU9K 3S16C 1I6HK 4A3IK 4A3KC 3S2DC 3S15C 5C44C 3HOUC 3HOYC 4YFNA 4LJZA 2NVXK 3GTJK 3S1QK 4MEYA 3GTGK 3H0GC 2JA8C 5M5XK 4LLGA 4Q5SA 3GTQK 2O5JA 1TWAC 4OIPA 5FJ8K 3S1RK 4BBSK 3M4OC 3S1NK 5C3EK 2PMZD 3S2HC 2R92K 3GTKK 3GTLC 1TWHC 1BDFA 2A6HA 4G7HA 3PO2C 4A3KK 2NVYC 5IP9C 1WCMC 2VUMC 4A3LK 3S2DK 4A3FK 5M3FK 4KMUA 3GTOC 5IYBC 3GTPC 4XSXA 2JA5C 4A3FC 1I50K 1TWFK 3GTMK 2Y0SD 4Y7NC 2A6EA 2B63K 3GTQC 4AYBL 1TWAK 3RZDC 3HKZD 2R7ZC 1ZYRA 4OIRA 1I6VA 5C4XK 3K7AC 5IYDC 3K7AK 2R93K 4X6AK 1I3QC 3S14K 1Y1VC 4LK0A 4C3JC 1I50C 2PA8D 1Y1WC 5M5YK 2JA5K 3S1MK 3HOXK 4BXXK 4A93K 3EQLA 2E2IC 4YG2A 3GTMC 4A3EC 4XLPA 2B63C 4A3DK 4A3BC 3HOVC 1R9TK 2E2IK 4NOIA 3CQZK 2NVTK 2E2JC 3HOVK
chains in the Genus database with same CATH superfamily
1WOOA 1WIHA 3DXJA 1TWHK 1WOPA 2NVXC 1O24A 5D4DA 4C3IC 1J6WA 1B4BA 1VGXA 1DD5A 2KXYA 1TWCC 4JK1A 5IYDK 4A3IC 4WFAS 3RZOC 3PO3C 1HQMA 4A3MK 3RZOK 4KN4A 4KASA 1Y1WK 3OPFA 3A8IA 4P5BA 2E2HK 3T02A 1Y1VA 1I50A 5FLMK 4A3JC 4KARA 3GTLA 3G4AA 2E2HC 2CFAA 1JQWA 1EQRA 1VJEA 4QJVB 3PO2K 1F7VA 3AD9C 3L4JA 4Q4ZA 2R93C 4YFKA 3N0CA 5IOTA 4A3BK 1XPPA 3A8KA 4LK1A 3GEEA 3S1RC 1ISEA 1TWGC 3H0GK 2R7ZK 1WQHA 5HQHA 1ZXOA 3FHZA 5L46A 2RGRA 3TFHA 2WAQL 3I4MC 4Y7NK 1INNA 1ZBSA 1AB4A 5TMCA 5CJ9A 2VUMA 3AD7C 4OIOA 3CQZA 1SMYA 3GTLK 1USOA 1BGWA 2R92A 1J6XA 3S15C 4YFNA 2FQTA 2JA8C 2P5MA 1XZQB 1TWAC 5FJ8K 3S1RK 3M4OC 4WJ3M 3S2HC 3GTKK 3GTLC 1TWHC 1DCOA 2A6HA 1F7UA 2NVYC 4A3LK 1WCMC 4A3FK 5M3FK 3G4CA 4Y7NC 3VA7A 1TWAK 3ERED 3FOFA 3Q3QA 3TTGA 1G51A 1DCPA 3IPJA 4IOCS 5IYDC 3GTJA 1I3QC 1Y1WC 5M5YK 4ILDA 1TWHA 5TJ3A 3T00A 1K83A 4DDQA 4A93K 4GTDA 1R9TK 1JOEA 3L4KA 5IP9K 3H3VL 5EGHA 3GTKC 4A3MC 3QX3A 1I3QK 5FLMC 1XZPA 5DM7S 1IW7A 1B4AA 2V6UA 1IL2A 4BLAA 1TWGK 3H0GA 4C3IK 1TWGA 4G7ZA 5C44K 3HOYK 4QJVA 2L5NA 3MMLB 1UV7A 1XZQA 4BXXC 3S17K 4WCES 4QIWD 2XCQA 3S1NC 5JVHS 1I6HC 3SZYA 1TWFC 3GTJC 1PJ7A 1I3QA 1IQ0A 4OINA 1SFOC 3HOWC 4O2DA 4BBRK 1SFOK 3HOWK 1GE9A 3OEPA 4KM9A 5JFEA 5M3MK 1HI9A 4BLBA 2JA8K 3GTOA 2GAHC 4X6AK 1R9TC 1YNNA 2PMZL 4Y52C 2CFAB 2JA6A 2KPUA 3S2HK 3AQPA 1O26A 2JA6K 5DM6S 4KN7A 2NVQC 1O29A 3LPXA 4LOWA 4C3HC 4A3CK 1WOSA 2BE5A 3BUEA 2R93A 5HL7S 1YX2A 1VRQC 3HOUC 4LJZA 1WQGA 1KQ4A 2NVXA 4Q5SA 1J98A 2O5JA 1PJ5A 3T01A 3S1NK 3CAGA 4G7HA 2ZUEA 3PO2C 1V5VA 3V4GA 1WORA 1XXBA 3GTPC 4U67S 4A3FC 2Y0SD 2A6EA 1FEUA 4KB4A 3BP3A 3SZZA 4AYBL 3FKIA 4P9SA 4OIRA 1R9TA 3LYWA 4RMFA 4GTCA 2R93K 3S14K 1O25A 1I50C 2JA5K 1TWFA 4BXXK 4KMHA 4YG2A 4XLPA 2B63C 2NVTK 2E2JC 5C4XK 2Y3PA 1SFOA 4BBRC 4C2MC 3PIOS 3H3VD 1YNJA 2KWAA 1WQFA 2ZUFA 4PAAA 3S14C 1F9NA 5JVOA 4C45A 4BY7C 2WB1D 3A8JA 4AYBD 4Y52K 4MQ9A 4C2MK 5TMFA 3I4NK 5IYBK 3HOXC 4ZH4A 3I4MK 4A3DC 1Y1VK 4C3JK 4A3EK 5IYCC 3S17C 2L3UA 1EI6A 1DCHA 3AD8C 5IYCK 1YCLA 4XSZA 1IE0A 3NUHA 2NVTC 2GSNA 1O2BA 4WFBS 3S15K 4G0UA 3GTMA 1Y1WA 4A3GK 4X6AC 3M3YK 2PPBA 3HKZL 2YU9C 1EK8A 1TWAA 3M4OK 4KMAA 2NVYA 3PO3K 4GTBA 5EGEA 4BKWA 1WCMK 2XCOA 4YFXA 1WCMA 2XCRB 3GTPK 2RH6A 1XXAA 1K83K 1VLOA 1BS2A 5IORA 3HOZK 2JH3A 2PHCB 2JA7K 1TWCK 1C0AA 1IBAA 4FZBA 4XCHA 1WSVA 2JA7C 4QIWL 1PJ6A 2ZJRS 4WILA 4GT9A 3FOEA 1IS1A 4BY7K 4GTFA 4GTLA 4J3NA 1EH1A 2CW0A 4A3GC 2EBBA 5JVGS 1JVIA 5C4XC 2E2JK 1VH2A 3WODA 5C4JK 3GTKA 2YU9K 3S16C 4G0VA 2GSOA 1J6VA 2NVXK 4MEYA 3DLLS 3H0GC 2GSUA 3BP8C 5M5XK 2E2HA 1ZQ1C 4BBSK 4LR2A 4KDDA 5IOQA 2PMZD 1WSRA 2R92K 4A3KK 3S2DK 3GEIA 5IP9C 2FQOA 2E2IA 4IO9S 3GTGA 2JA5C 1I50K 1F93A 3GSIA 2ZFZA 2B63K 3GTQC 3HXAA 3LAPA 4KM8A 3RZDC 3TFIA 1I6VA 3K7AC 3PIPS 4M1XA 1Y1VC 4LK0A 4C3JC 3S1MK 3HOXK 2YU9A 3EQLA 2E2IC 1BJTA 5CHPA 4NOIA 2KQ1A 4FM9A 2VUMC 3JSTA 4AH6A 4A3LC 2NVYK 4XLNA 2R92C 3I4NC 4OIQA 3S1QC 2WAQD 3N3YA 3LAJA 4WFNS 4KATA 2JA7A 3HOZC 2Y0SL 3RZDK 2JA6C 2B63A 3HOUK 1ZVUA 3GEHA 2P8TA 5IOSA 1RU0A 4A3CC 4C3HK 3CQZC 3S1MC 3M3YC 3GTGC 3FKIC 3CF5S 3GIRA 2R7ZA 2NVQK 5E68A 4BY1K 2D6FC 2GAGC 3GTOK 4G7OA 1K83C 2A68A 4G0WA 3FKIK 5IP7C 2V6TA 1XZPB 2PA8L 3GTPA 4KC6A 3GTQA 4BY1C 4A3JK 2A69A 3OREA 2JA5A 3S0XA 2ZJQS 1TWCA 4A93C 1L0WA 4WJ4A 4LQYA 3S16K 4P5AA 5C4JC 2O5IA 4GTEA 4GZYA 4GTAA 2WB1L 1USMA 4MEXA 5M5WK 4BBSC 1XXCA 2VUMK 1O2FB 5C3EC 5IP7K 4GFQA 1I6HK 4A3IK 4A3KC 3S2DC 3AQOA 5C44C 3HOYC 3N0BA 1O2AA 3GDZA 3GTJK 4KB2A 3S1QK 4PABA 3GTGK 1O28A 4LLGA 3GTQK 4OIPA 5C3EK 4WF9S 1O27A 2W7VA 1BDFA 1EFWA 2ZJPS 4KMUA 3GTOC 5IYBC 4XSXA 1TWFK 3GTMK 5HL8A 3HKZD 2R7ZC 1ZYRA 4KAWX 2V6SA 4KMDA 3TFJA 3ADAC 3AH5A 3K7AK 2PA8D 1X31C 3GTMC 4A3EC 4IOAS 4A3DK 4A3BC 3HOVC 2E2IK 3CQZK 3HOVK
chains in the Genus database with same CATH topology
4A3LC 2NVYK 4BBRC 4C2MC 5IP9K 3H3VL 4XLNA 2R92C 3GTKC 4A3MC 1YNJA 3DXJA 3H3VD 1TWHK 3I4NC 4OIQA 3S14C 3S1QC 5FLMC 2WAQD 1I3QK 2NVXC 4BY7C 5D4DA 2WB1D 1IW7A 4C3IC 4AYBD 3HOZC 1TWGK 4Y52K 4C3IK 2Y0SL 1TWCC 4JK1A 3RZDK 2JA6C 5IYDK 4G7ZA 4A3IC 5C44K 3HOUK 4QJVA 4MQ9A 4C2MK 3HOYK 5TMFA 3I4NK 3RZOC 3PO3C 1HQMA 5IYBK 4A3MK 3HOXC 4BXXC 3S17K 3RZOK 4ZH4A 3I4MK 4KN4A 4A3DC 1Y1VK 4C3JK 4A3EK 5IYCC 3S17C 1Y1WK 4A3CC 4C3HK 3CQZC 3S1MC 3M3YC 5IYCK 3GTGC 4QIWD 4XSZA 3FKIC 2E2HK 2NVTC 3S1NC 3S15K 1I6HC 2NVQK 1TWFC 4BY1K 3GTOK 3GTJC 4G7OA 5FLMK 4A3GK 1K83C 4A3JC 4X6AC 2A68A 3M3YK 2PPBA 4OINA 1SFOC 2E2HC 3HOWC 3FKIK 5IP7C 2YU9C 3HKZL 4BBRK 3M4OK 4QJVB 1SFOK 3HOWK 3PO2K 3PO3K 2PA8L 1WCMK 5M3MK 4YFXA 4Q4ZA 2R93C 4YFKA 3GTPK 4BY1C 2JA8K 1K83K 1R9TC 2A69A 1XPPA 4A3JK 1YNNA 4LK1A 3S1RC 4A3BK 2PMZL 1TWGC 4Y52C 4A93C 3HOZK 3S2HK 3H0GK 2JA6K 2R7ZK 2JA7K 1TWCK 4KN7A 3S16K 2NVQC 2JA7C 4QIWL 5C4JC 2O5IA 4GZYA 2WAQL 4BY7K 3I4MC 4Y7NK 2WB1L 5TMCA 4C3HC 4A3CK 2BE5A 2CW0A 4OIOA 4A3GC 4MEXA 5M5WK 4BBSC 1SMYA 5C4XC 2E2JK 2VUMK 3GTLK 3WODA 5C3EC 5C4JK 5IP7K 2YU9K 3S16C 1I6HK 4A3IK 4A3KC 3S2DC 3S15C 5C44C 3HOUC 3HOYC 4YFNA 4LJZA 2NVXK 3GTJK 3S1QK 4MEYA 3GTGK 3H0GC 2JA8C 5M5XK 4LLGA 4Q5SA 3GTQK 2O5JA 1TWAC 4OIPA 5FJ8K 3S1RK 4BBSK 3M4OC 3S1NK 5C3EK 2PMZD 3S2HC 2R92K 3GTKK 3GTLC 1TWHC 1BDFA 2A6HA 4G7HA 3PO2C 4A3KK 2NVYC 5IP9C 1WCMC 2VUMC 4A3LK 3S2DK 4A3FK 5M3FK 4KMUA 3GTOC 5IYBC 3GTPC 4XSXA 2JA5C 4A3FC 1I50K 1TWFK 3GTMK 2Y0SD 4Y7NC 2A6EA 2B63K 3GTQC 4AYBL 1TWAK 3RZDC 3HKZD 2R7ZC 1ZYRA 4OIRA 1I6VA 5C4XK 3K7AC 5IYDC 3K7AK 2R93K 4X6AK 1I3QC 3S14K 1Y1VC 4LK0A 4C3JC 1I50C 2PA8D 1Y1WC 5M5YK 2JA5K 3S1MK 3HOXK 4BXXK 4A93K 3EQLA 2E2IC 4YG2A 3GTMC 4A3EC 4XLPA 2B63C 4A3DK 4A3BC 3HOVC 1R9TK 2E2IK 4NOIA 3CQZK 2NVTK 2E2JC 3HOVK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3L C;  2NVY K;  4BBR C;  4C2M C;  5IP9 K;  3H3V L;  4XLN A;  2R92 C;  3GTK C;  4A3M C;  1YNJ A;  3DXJ A;  3H3V D;  1TWH K;  3I4N C;  4OIQ A;  3S14 C;  3S1Q C;  5FLM C;  2WAQ D;  1I3Q K;  2NVX C;  4BY7 C;  5D4D A;  2WB1 D;  1IW7 A;  4C3I C;  4AYB D;  3HOZ C;  1TWG K;  4Y52 K;  4C3I K;  2Y0S L;  1TWC C;  4JK1 A;  3RZD K;  2JA6 C;  5IYD K;  4G7Z A;  4A3I C;  5C44 K;  3HOU K;  4QJV A;  4MQ9 A;  4C2M K;  3HOY K;  5TMF A;  3I4N K;  3RZO C;  3PO3 C;  1HQM A;  5IYB K;  4A3M K;  3HOX C;  4BXX C;  3S17 K;  3RZO K;  4ZH4 A;  3I4M K;  4KN4 A;  4A3D C;  1Y1V K;  4C3J K;  4A3E K;  5IYC C;  3S17 C;  1Y1W K;  4A3C C;  4C3H K;  3CQZ C;  3S1M C;  3M3Y C;  5IYC K;  3GTG C;  4QIW D;  4XSZ A;  3FKI C;  2E2H K;  2NVT C;  3S1N C;  3S15 K;  1I6H C;  2NVQ K;  1TWF C;  4BY1 K;  3GTO K;  3GTJ C;  4G7O A;  5FLM K;  4A3G K;  1K83 C;  4A3J C;  4X6A C;  2A68 A;  3M3Y K;  2PPB A;  4OIN A;  1SFO C;  2E2H C;  3HOW C;  3FKI K;  5IP7 C;  2YU9 C;  3HKZ L;  4BBR K;  3M4O K;  4QJV B;  1SFO K;  3HOW K;  3PO2 K;  3PO3 K;  2PA8 L;  1WCM K;  5M3M K;  4YFX A;  4Q4Z A;  2R93 C;  4YFK A;  3GTP K;  4BY1 C;  2JA8 K;  1K83 K;  1R9T C;  2A69 A;  1XPP A;  4A3J K;  1YNN A;  4LK1 A;  3S1R C;  4A3B K;  2PMZ L;  1TWG C;  4Y52 C;  4A93 C;  3HOZ K;  3S2H K;  3H0G K;  2JA6 K;  2R7Z K;  2JA7 K;  1TWC K;  4KN7 A;  3S16 K;  2NVQ C;  2JA7 C;  4QIW L;  5C4J C;  2O5I A;  4GZY A;  2WAQ L;  4BY7 K;  3I4M C;  4Y7N K;  2WB1 L;  5TMC A;  4C3H C;  4A3C K;  2BE5 A;  2CW0 A;  4OIO A;  4A3G C;  4MEX A;  5M5W K;  4BBS C;  1SMY A;  5C4X C;  2E2J K;  2VUM K;  3GTL K;  3WOD A;  5C3E C;  5C4J K;  5IP7 K;  2YU9 K;  3S16 C;  1I6H K;  4A3I K;  4A3K C;  3S2D C;  3S15 C;  5C44 C;  3HOU C;  3HOY C;  4YFN A;  4LJZ A;  2NVX K;  3GTJ K;  3S1Q K;  4MEY A;  3GTG K;  3H0G C;  2JA8 C;  5M5X K;  4LLG A;  4Q5S A;  3GTQ K;  2O5J A;  1TWA C;  4OIP A;  5FJ8 K;  3S1R K;  4BBS K;  3M4O C;  3S1N K;  5C3E K;  2PMZ D;  3S2H C;  2R92 K;  3GTK K;  3GTL C;  1TWH C;  1BDF A;  2A6H A;  4G7H A;  3PO2 C;  4A3K K;  2NVY C;  5IP9 C;  1WCM C;  2VUM C;  4A3L K;  3S2D K;  4A3F K;  5M3F K;  4KMU A;  3GTO C;  5IYB C;  3GTP C;  4XSX A;  2JA5 C;  4A3F C;  1I50 K;  1TWF K;  3GTM K;  2Y0S D;  4Y7N C;  2A6E A;  2B63 K;  3GTQ C;  4AYB L;  1TWA K;  3RZD C;  3HKZ D;  2R7Z C;  1ZYR A;  4OIR A;  1I6V A;  5C4X K;  3K7A C;  5IYD C;  3K7A K;  2R93 K;  4X6A K;  1I3Q C;  3S14 K;  1Y1V C;  4LK0 A;  4C3J C;  1I50 C;  2PA8 D;  1Y1W C;  5M5Y K;  2JA5 K;  3S1M K;  3HOX K;  4BXX K;  4A93 K;  3EQL A;  2E2I C;  4YG2 A;  3GTM C;  4A3E C;  4XLP A;  2B63 C;  4A3D K;  4A3B C;  3HOV C;  1R9T K;  2E2I K;  4NOI A;  3CQZ K;  2NVT K;  2E2J C;  3HOV K; 
#chains in the Genus database with same CATH topology
 1WOO A;  1WIH A;  3DXJ A;  1TWH K;  1WOP A;  2NVX C;  1O24 A;  5D4D A;  4C3I C;  1J6W A;  1B4B A;  1VGX A;  1DD5 A;  2KXY A;  1TWC C;  4JK1 A;  5IYD K;  4A3I C;  4WFA S;  3RZO C;  3PO3 C;  1HQM A;  4A3M K;  3RZO K;  4KN4 A;  4KAS A;  1Y1W K;  3OPF A;  3A8I A;  4P5B A;  2E2H K;  3T02 A;  1Y1V A;  1I50 A;  5FLM K;  4A3J C;  4KAR A;  3GTL A;  3G4A A;  2E2H C;  2CFA A;  1JQW A;  1EQR A;  1VJE A;  4QJV B;  3PO2 K;  1F7V A;  3AD9 C;  3L4J A;  4Q4Z A;  2R93 C;  4YFK A;  3N0C A;  5IOT A;  4A3B K;  1XPP A;  3A8K A;  4LK1 A;  3GEE A;  3S1R C;  1ISE A;  1TWG C;  3H0G K;  2R7Z K;  1WQH A;  5HQH A;  1ZXO A;  3FHZ A;  5L46 A;  2RGR A;  3TFH A;  2WAQ L;  3I4M C;  4Y7N K;  1INN A;  1ZBS A;  1AB4 A;  5TMC A;  5CJ9 A;  2VUM A;  3AD7 C;  4OIO A;  3CQZ A;  1SMY A;  3GTL K;  1USO A;  1BGW A;  2R92 A;  1J6X A;  3S15 C;  4YFN A;  2FQT A;  2JA8 C;  2P5M A;  1XZQ B;  1TWA C;  5FJ8 K;  3S1R K;  3M4O C;  4WJ3 M;  3S2H C;  3GTK K;  3GTL C;  1TWH C;  1DCO A;  2A6H A;  1F7U A;  2NVY C;  4A3L K;  1WCM C;  4A3F K;  5M3F K;  3G4C A;  4Y7N C;  3VA7 A;  1TWA K;  3ERE D;  3FOF A;  3Q3Q A;  3TTG A;  1G51 A;  1DCP A;  3IPJ A;  4IOC S;  5IYD C;  3GTJ A;  1I3Q C;  1Y1W C;  5M5Y K;  4ILD A;  1TWH A;  5TJ3 A;  3T00 A;  1K83 A;  4DDQ A;  4A93 K;  4GTD A;  1R9T K;  1JOE A;  3L4K A;  5IP9 K;  3H3V L;  5EGH A;  3GTK C;  4A3M C;  3QX3 A;  1I3Q K;  5FLM C;  1XZP A;  5DM7 S;  1IW7 A;  1B4A A;  2V6U A;  1IL2 A;  4BLA A;  1TWG K;  3H0G A;  4C3I K;  1TWG A;  4G7Z A;  5C44 K;  3HOY K;  4QJV A;  2L5N A;  3MML B;  1UV7 A;  1XZQ A;  4BXX C;  3S17 K;  4WCE S;  4QIW D;  2XCQ A;  3S1N C;  5JVH S;  1I6H C;  3SZY A;  1TWF C;  3GTJ C;  1PJ7 A;  1I3Q A;  1IQ0 A;  4OIN A;  1SFO C;  3HOW C;  4O2D A;  4BBR K;  1SFO K;  3HOW K;  1GE9 A;  3OEP A;  4KM9 A;  5JFE A;  5M3M K;  1HI9 A;  4BLB A;  2JA8 K;  3GTO A;  2GAH C;  4X6A K;  1R9T C;  1YNN A;  2PMZ L;  4Y52 C;  2CFA B;  2JA6 A;  2KPU A;  3S2H K;  3AQP A;  1O26 A;  2JA6 K;  5DM6 S;  4KN7 A;  2NVQ C;  1O29 A;  3LPX A;  4LOW A;  4C3H C;  4A3C K;  1WOS A;  2BE5 A;  3BUE A;  2R93 A;  5HL7 S;  1YX2 A;  1VRQ C;  3HOU C;  4LJZ A;  1WQG A;  1KQ4 A;  2NVX A;  4Q5S A;  1J98 A;  2O5J A;  1PJ5 A;  3T01 A;  3S1N K;  3CAG A;  4G7H A;  2ZUE A;  3PO2 C;  1V5V A;  3V4G A;  1WOR A;  1XXB A;  3GTP C;  4U67 S;  4A3F C;  2Y0S D;  2A6E A;  1FEU A;  4KB4 A;  3BP3 A;  3SZZ A;  4AYB L;  3FKI A;  4P9S A;  4OIR A;  1R9T A;  3LYW A;  4RMF A;  4GTC A;  2R93 K;  3S14 K;  1O25 A;  1I50 C;  2JA5 K;  1TWF A;  4BXX K;  4KMH A;  4YG2 A;  4XLP A;  2B63 C;  2NVT K;  2E2J C;  5C4X K;  2Y3P A;  1SFO A;  4BBR C;  4C2M C;  3PIO S;  3H3V D;  1YNJ A;  2KWA A;  1WQF A;  2ZUF A;  4PAA A;  3S14 C;  1F9N A;  5JVO A;  4C45 A;  4BY7 C;  2WB1 D;  3A8J A;  4AYB D;  4Y52 K;  4MQ9 A;  4C2M K;  5TMF A;  3I4N K;  5IYB K;  3HOX C;  4ZH4 A;  3I4M K;  4A3D C;  1Y1V K;  4C3J K;  4A3E K;  5IYC C;  3S17 C;  2L3U A;  1EI6 A;  1DCH A;  3AD8 C;  5IYC K;  1YCL A;  4XSZ A;  1IE0 A;  3NUH A;  2NVT C;  2GSN A;  1O2B A;  4WFB S;  3S15 K;  4G0U A;  3GTM A;  1Y1W A;  4A3G K;  4X6A C;  3M3Y K;  2PPB A;  3HKZ L;  2YU9 C;  1EK8 A;  1TWA A;  3M4O K;  4KMA A;  2NVY A;  3PO3 K;  4GTB A;  5EGE A;  4BKW A;  1WCM K;  2XCO A;  4YFX A;  1WCM A;  2XCR B;  3GTP K;  2RH6 A;  1XXA A;  1K83 K;  1VLO A;  1BS2 A;  5IOR A;  3HOZ K;  2JH3 A;  2PHC B;  2JA7 K;  1TWC K;  1C0A A;  1IBA A;  4FZB A;  4XCH A;  1WSV A;  2JA7 C;  4QIW L;  1PJ6 A;  2ZJR S;  4WIL A;  4GT9 A;  3FOE A;  1IS1 A;  4BY7 K;  4GTF A;  4GTL A;  4J3N A;  1EH1 A;  2CW0 A;  4A3G C;  2EBB A;  5JVG S;  1JVI A;  5C4X C;  2E2J K;  1VH2 A;  3WOD A;  5C4J K;  3GTK A;  2YU9 K;  3S16 C;  4G0V A;  2GSO A;  1J6V A;  2NVX K;  4MEY A;  3DLL S;  3H0G C;  2GSU A;  3BP8 C;  5M5X K;  2E2H A;  1ZQ1 C;  4BBS K;  4LR2 A;  4KDD A;  5IOQ A;  2PMZ D;  1WSR A;  2R92 K;  4A3K K;  3S2D K;  3GEI A;  5IP9 C;  2FQO A;  2E2I A;  4IO9 S;  3GTG A;  2JA5 C;  1I50 K;  1F93 A;  3GSI A;  2ZFZ A;  2B63 K;  3GTQ C;  3HXA A;  3LAP A;  4KM8 A;  3RZD C;  3TFI A;  1I6V A;  3K7A C;  3PIP S;  4M1X A;  1Y1V C;  4LK0 A;  4C3J C;  3S1M K;  3HOX K;  2YU9 A;  3EQL A;  2E2I C;  1BJT A;  5CHP A;  4NOI A;  2KQ1 A;  4FM9 A;  2VUM C;  3JST A;  4AH6 A;  4A3L C;  2NVY K;  4XLN A;  2R92 C;  3I4N C;  4OIQ A;  3S1Q C;  2WAQ D;  3N3Y A;  3LAJ A;  4WFN S;  4KAT A;  2JA7 A;  3HOZ C;  2Y0S L;  3RZD K;  2JA6 C;  2B63 A;  3HOU K;  1ZVU A;  3GEH A;  2P8T A;  5IOS A;  1RU0 A;  4A3C C;  4C3H K;  3CQZ C;  3S1M C;  3M3Y C;  3GTG C;  3FKI C;  3CF5 S;  3GIR A;  2R7Z A;  2NVQ K;  5E68 A;  4BY1 K;  2D6F C;  2GAG C;  3GTO K;  4G7O A;  1K83 C;  2A68 A;  4G0W A;  3FKI K;  5IP7 C;  2V6T A;  1XZP B;  2PA8 L;  3GTP A;  4KC6 A;  3GTQ A;  4BY1 C;  4A3J K;  2A69 A;  3ORE A;  2JA5 A;  3S0X A;  2ZJQ S;  1TWC A;  4A93 C;  1L0W A;  4WJ4 A;  4LQY A;  3S16 K;  4P5A A;  5C4J C;  2O5I A;  4GTE A;  4GZY A;  4GTA A;  2WB1 L;  1USM A;  4MEX A;  5M5W K;  4BBS C;  1XXC A;  2VUM K;  1O2F B;  5C3E C;  5IP7 K;  4GFQ A;  1I6H K;  4A3I K;  4A3K C;  3S2D C;  3AQO A;  5C44 C;  3HOY C;  3N0B A;  1O2A A;  3GDZ A;  3GTJ K;  4KB2 A;  3S1Q K;  4PAB A;  3GTG K;  1O28 A;  4LLG A;  3GTQ K;  4OIP A;  5C3E K;  4WF9 S;  1O27 A;  2W7V A;  1BDF A;  1EFW A;  2ZJP S;  4KMU A;  3GTO C;  5IYB C;  4XSX A;  1TWF K;  3GTM K;  5HL8 A;  3HKZ D;  2R7Z C;  1ZYR A;  4KAW X;  2V6S A;  4KMD A;  3TFJ A;  3ADA C;  3AH5 A;  3K7A K;  2PA8 D;  1X31 C;  3GTM C;  4A3E C;  4IOA S;  4A3D K;  4A3B C;  3HOV C;  2E2I K;  3CQZ K;  3HOV K; 
#chains in the Genus database with same CATH homology
 4A3L C;  2NVY K;  4BBR C;  4C2M C;  5IP9 K;  3H3V L;  4XLN A;  2R92 C;  3GTK C;  4A3M C;  1YNJ A;  3DXJ A;  3H3V D;  1TWH K;  3I4N C;  4OIQ A;  3S14 C;  3S1Q C;  5FLM C;  2WAQ D;  1I3Q K;  2NVX C;  4BY7 C;  5D4D A;  2WB1 D;  1IW7 A;  4C3I C;  4AYB D;  3HOZ C;  1TWG K;  4Y52 K;  4C3I K;  2Y0S L;  1TWC C;  4JK1 A;  3RZD K;  2JA6 C;  5IYD K;  4G7Z A;  4A3I C;  5C44 K;  3HOU K;  4QJV A;  4MQ9 A;  4C2M K;  3HOY K;  5TMF A;  3I4N K;  3RZO C;  3PO3 C;  1HQM A;  5IYB K;  4A3M K;  3HOX C;  4BXX C;  3S17 K;  3RZO K;  4ZH4 A;  3I4M K;  4KN4 A;  4A3D C;  1Y1V K;  4C3J K;  4A3E K;  5IYC C;  3S17 C;  1Y1W K;  4A3C C;  4C3H K;  3CQZ C;  3S1M C;  3M3Y C;  5IYC K;  3GTG C;  4QIW D;  4XSZ A;  3FKI C;  2E2H K;  2NVT C;  3S1N C;  3S15 K;  1I6H C;  2NVQ K;  1TWF C;  4BY1 K;  3GTO K;  3GTJ C;  4G7O A;  5FLM K;  4A3G K;  1K83 C;  4A3J C;  4X6A C;  2A68 A;  3M3Y K;  2PPB A;  4OIN A;  1SFO C;  2E2H C;  3HOW C;  3FKI K;  5IP7 C;  2YU9 C;  3HKZ L;  4BBR K;  3M4O K;  4QJV B;  1SFO K;  3HOW K;  3PO2 K;  3PO3 K;  2PA8 L;  1WCM K;  5M3M K;  4YFX A;  4Q4Z A;  2R93 C;  4YFK A;  3GTP K;  4BY1 C;  2JA8 K;  1K83 K;  1R9T C;  2A69 A;  1XPP A;  4A3J K;  1YNN A;  4LK1 A;  3S1R C;  4A3B K;  2PMZ L;  1TWG C;  4Y52 C;  4A93 C;  3HOZ K;  3S2H K;  3H0G K;  2JA6 K;  2R7Z K;  2JA7 K;  1TWC K;  4KN7 A;  3S16 K;  2NVQ C;  2JA7 C;  4QIW L;  5C4J C;  2O5I A;  4GZY A;  2WAQ L;  4BY7 K;  3I4M C;  4Y7N K;  2WB1 L;  5TMC A;  4C3H C;  4A3C K;  2BE5 A;  2CW0 A;  4OIO A;  4A3G C;  4MEX A;  5M5W K;  4BBS C;  1SMY A;  5C4X C;  2E2J K;  2VUM K;  3GTL K;  3WOD A;  5C3E C;  5C4J K;  5IP7 K;  2YU9 K;  3S16 C;  1I6H K;  4A3I K;  4A3K C;  3S2D C;  3S15 C;  5C44 C;  3HOU C;  3HOY C;  4YFN A;  4LJZ A;  2NVX K;  3GTJ K;  3S1Q K;  4MEY A;  3GTG K;  3H0G C;  2JA8 C;  5M5X K;  4LLG A;  4Q5S A;  3GTQ K;  2O5J A;  1TWA C;  4OIP A;  5FJ8 K;  3S1R K;  4BBS K;  3M4O C;  3S1N K;  5C3E K;  2PMZ D;  3S2H C;  2R92 K;  3GTK K;  3GTL C;  1TWH C;  1BDF A;  2A6H A;  4G7H A;  3PO2 C;  4A3K K;  2NVY C;  5IP9 C;  1WCM C;  2VUM C;  4A3L K;  3S2D K;  4A3F K;  5M3F K;  4KMU A;  3GTO C;  5IYB C;  3GTP C;  4XSX A;  2JA5 C;  4A3F C;  1I50 K;  1TWF K;  3GTM K;  2Y0S D;  4Y7N C;  2A6E A;  2B63 K;  3GTQ C;  4AYB L;  1TWA K;  3RZD C;  3HKZ D;  2R7Z C;  1ZYR A;  4OIR A;  1I6V A;  5C4X K;  3K7A C;  5IYD C;  3K7A K;  2R93 K;  4X6A K;  1I3Q C;  3S14 K;  1Y1V C;  4LK0 A;  4C3J C;  1I50 C;  2PA8 D;  1Y1W C;  5M5Y K;  2JA5 K;  3S1M K;  3HOX K;  4BXX K;  4A93 K;  3EQL A;  2E2I C;  4YG2 A;  3GTM C;  4A3E C;  4XLP A;  2B63 C;  4A3D K;  4A3B C;  3HOV C;  1R9T K;  2E2I K;  4NOI A;  3CQZ K;  2NVT K;  2E2J C;  3HOV K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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