4XSXA

Crystal structure of cbr 703 bound to escherichia coli rna polymerase holoenzyme
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/antibiotic
molecule keywords DNA-directed RNA polymerase subunit alpha
publication title CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
pubmed doi rcsb
source organism Escherichia coli (strain k12)
total genus 42
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4xsxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4xsxA01
3I4NC 3S2DC 4C3IC 2R92C 2JA6K 3S15K 5D4DA 5C4JC 3HOUK 3GTGK 3CQZC 3HOVC 4A93K 4A3DK 4X6AC 3S1QK 4C2MC 4YG2A 4Y52C 4Q5SA 3S1MC 4A3JK 3FKIK 1SFOK 4YFKA 4A3GC 3HOZC 3RZOC 1Y1VC 4G7ZA 4A3JC 4A3CC 1XPPA 1BDFA 4LLGA 3H0GK 4QJVB 3GTJC 3HOWC 5IYCK 3GTLK 3I4MK 2JA6C 3S15C 4A3IK 4BBSK 4QIWL 2VUMK 3GTGC 1R9TK 5IYDK 4KN7A 4A93C 1TWAK 3PO3K 3H3VL 3HOYK 3S1NK 3S1QC 2A68A 1I6VA 4QJVA 4OINA 5M3MK 1TWHC 2PPBA 4OIRA 5TMFA 1YNJA 3FKIC 1SFOC 4A3BK 3GTPC 3GTJK 5M5YK 4LK1A 3H0GC 3S16K 3GTLC 2WAQL 5C4XK 2BE5A 4YFXA 5IYBK 4NOIA 4A3IC 3H3VD 2VUMC 1TWGK 4GZYA 5IYDC 3PO3C 2O5IA 4C3JK 3S1NC 4BY7K 5C44K 2JA5K 2E2IK 4BY1K 2JA8K 1TWCC 4A3BC 4ZH4A 2WAQD 3HKZL 5IP9C 3S2HK 3S14K 3S16C 4C3HK 2B63K 4OIQA 2YU9C 5C4XC 4BBRK 5IYBC 4A3MK 3RZDK 1IW7A 1TWGC 4XSZA 4BXXK 4MEXA 5IP7K 3HOUC 4C3JC 4BY7C 4A3DC 4A3LK 5C44C 2JA5C 3HKZD 2E2IC 4BY1C 3HOXK 2JA8C 2NVYK 3S1RK 2E2HK 2A6EA 2R93K 4KMUA 3S2HC 3S14C 3HOWK 3RZDC 2B63C 2WB1L 4BBRC 4A3MC 4MQ9A 3GTOK 5IYCC 3I4MC 4BBSC 5M5WK 4BXXC 2A6HA 1Y1WK 3PO2K 1R9TC 3GTKK 1TWAC 2E2JK 4LK0A 2PA8L 3HOYC 2NVTK 3HOXC 5C3EK 3M3YK 2NVYC 4G7HA 2E2HC 2NVQK 3M4OK 5FJ8K 2WB1D 2NVXK 1I50K 3I4NK 3S2DK 1K83C 3GTOC 3HOVK 5M3FK 2PA8D 1Y1WC 4JK1A 4A3FK 4YFNA 3GTKC 4G7OA 2E2JC 2Y0SL 1I6HK 4XSXA 1SMYA 5FLMK 4LJZA 3S1MK 2NVTC 5C3EC 3M3YC 3M4OC 1WCMK 5M5XK 4A3CK 2NVXC 3GTMK 1I50C 2R7ZK 3WODA 1I3QK 4Y7NK 4A3EK 3S17K 3EQLA 4C3HC 4OIOA 5TMCA 2Y0SD 4A3FC 4A3KK 5IP7C 1I6HC 1TWFK 5FLMC 1TWHK 3K7AK 4KN4A 4Q4ZA 2PMZL 2JA7K 4A3LC 1HQMA 4MEYA 4XLNA 3GTPK 1WCMC 3S1RC 3GTMC 2R7ZC 1I3QC 4Y7NC 4A3EC 2R93C 2O5JA 1K83K 3GTQK 3S17C 1ZYRA 4AYBL 4C3IK 2R92K 5C4JK 3CQZK 2PMZD 4A3KC 3PO2C 4X6AK 1TWFC 2CW0A 1YNNA 3K7AC 4C2MK 2JA7C 4Y52K 1TWCK 2A69A 5IP9K 3DXJA 2NVQC 3HOZK 4QIWD 4AYBD 1Y1VK 3RZOK 2YU9K 4A3GK 4XLPA 4OIPA 3GTQC
chains in the Genus database with same CATH superfamily
3BP3A 2PHCB 5L46A 3CQZC 3AD7C 1XXAA 4A3DK 4GTCA 4X6AC 1O2BA 4YG2A 3AQPA 3IPJA 3S1MC 1SFOK 4DDQA 1XPPA 4A3GC 3RZOC 1Y1VC 4G7ZA 1IE0A 3OREA 5M5YK 3RZDK 2ZJPS 4KARA 4BLAA 2NVXA 3GTLK 2JA6C 4A3IK 4BBSK 3GTGC 4KN7A 4A93C 1TWAK 3T02A 3GEHA 2XCQA 3HOYK 3PO3K 3SZZA 3S1QC 1C0AA 1I6VA 2W7VA 2ZUEA 3FKIC 1DCPA 1WCMA 2P8TA 4BKWA 4U67S 2BE5A 4YFXA 5IYBK 1WORA 2VUMC 3S1NC 2KQ1A 5IORA 2JA8K 4ZH4A 2V6UA 4FM9A 1EK8A 4WJ3M 4OIQA 5C4XC 4O2DA 3SZYA 4MEXA 4BXXK 3HOUC 3CQZA 4BY7C 1WOOA 3CAGA 1VRQC 5C44C 2JA5C 2E2IC 1O24A 3S1RK 4KC6A 2R93K 4KMUA 3S2HC 1VGXA 3GDZA 4P9SA 2WB1L 4BBRC 4A3MC 2R7ZA 3I4MC 2JA6A 3GTGA 3TFHA 3GTKK 2NVTK 5C3EK 1WSRA 3M3YK 2NVYC 2E2HC 2NVQK 3FKIA 3M4OK 2WB1D 2GAGC 3TFJA 5TJ3A 2Y3PA 3GTOC 2KPUA 2XCOA 4A3FK 3ADAC 2Y0SL 1I6HK 1J6VA 1GE9A 1EI6A 3GTMK 1I3QK 4Y7NK 2V6TA 5DM7S 5CHPA 2Y0SD 2CFAB 3V4GA 1TWFK 2P5MA 1TWHK 3K7AK 2JA5A 2E2IA 4XLNA 5IOQA 2R92K 3CF5S 4GTLA 4A3KC 4KATA 4Y52K 1B4BA 1WQFA 3OPFA 5IP9K 1DD5A 2NVYA 2E2HA 3HOZK 4QIWD 1XZPA 4A3JK 1K83C 4OIPA 2XCRB 1BJTA 3I4NC 3S2DC 4C3IC 4GTDA 3GTOA 5D4DA 2JH3A 1ZXOA 4C2MC 3GEEA 2D6FC 4LOWA 3FOFA 4A3CC 1BDFA 3H0GK 3GTJC 3HOWC 3FOEA 4P5AA 5HL8A 4KMDA 3N0CA 5TMFA 1SFOC 3L4KA 4A3BK 3GTPC 3GTJK 3S16K 3GTLC 4NOIA 4A3IC 1PJ7A 1TWGK 4GZYA 3PO3C 4C3JK 4G0WA 3AD8C 1TWCC 4KMAA 4LQYA 4XCHA 4GTEA 2YU9C 3OEPA 3GSIA 5IYBC 2RH6A 1K83A 4KB4A 1IW7A 1J98A 5IP7K 4BLBA 1ZBSA 4KB2A 1UV7A 2JA8C 4IOAS 1L0WA 1J6XA 2GAHC 1JOEA 5IYCC 1BGWA 5E68A 4BXXC 2A6HA 1WSVA 1Y1WK 1R9TC 4G7HA 1ISEA 1SFOA 5FJ8K 1I50K 3GTPA 5JVHS 3GTLA 3QX3A 3GTQA 2ZFZA 3BP8C 4JK1A 3GTKC 4G7OA 5FLMK 1VH2A 3S1MK 4G0UA 2NVTC 5C3EC 1ZQ1C 3M3YC 3M4OC 1TWCA 2R7ZK 3WODA 4A3EK 1Y1VA 4C3HC 2YU9A 1KQ4A 4A3FC 1I6HC 3A8IA 2JA7K 2PMZL 1BS2A 4A3LC 4MEYA 3GTMC 2FQOA 1I3QC 4Y7NC 4GTBA 4IOCS 4IO9S 4AYBL 3AQOA 5C4JK 1XXCA 2PMZD 1XZPB 3PO2C 2VUMA 1TWFC 2CW0A 1R9TA 3K7AC 3HXAA 4AYBD 3MMLB 1O25A 2R92C 3S15K 4WFBS 3HOUK 3HOVC 4WF9S 1V5VA 1J6WA 3GTKA 4Y52C 1B4AA 4YFKA 3HOZC 4A3JC 4LLGA 1O2FB 4KDDA 3I4MK 5JFEA 1XZQA 4QIWL 1DCHA 5IYDK 3S0XA 5CJ9A 3PIOS 1YCLA 4QJVA 5M3MK 4WCES 2PPBA 2ZUFA 3GTMA 3H0GC 1I3QA 2WAQL 1F93A 4J3NA 1JQWA 4GTAA 2O5IA 3AH5A 1IL2A 3A8JA 1TWFA 4BY1K 4A3BC 2WAQD 3N3YA 3FHZA 3S16C 3S14K 2B63K 1WQGA 4FZBA 1TWGC 4XSZA 4C3JC 4A3DC 3GIRA 4KMHA 4PABA 3HOXK 4P5BA 2A6EA 3RZDC 4MQ9A 4BBSC 1VJEA 3A8KA 1TWAC 2E2JK 4LK0A 2PA8L 3HOYC 1O27A 3DLLS 2NVXK 3LPXA 3I4NK 3L4JA 3S2DK 1O28A 3H0GA 1F7UA 2GSOA 1PJ5A 3VA7A 2PA8D 1Y1WC 1G51A 4YFNA 4XSXA 3JSTA 1EQRA 3TTGA 1WCMK 5M5XK 4A3CK 1EH1A 1I50C 3S17K 3Q3QA 3EQLA 2ZJRS 5JVGS 3GTJA 1TWGA 2FQTA 5HQHA 5EGEA 5FLMC 4Q4ZA 1O29A 1O2AA 1RU0A 1HQMA 4KAWX 3GTPK 3S1RC 3LYWA 2R7ZC 4A3EC 2R93C 2O5JA 3GTQK 2ZJQS 4LR2A 3CQZK 1WOSA 5IOSA 4X6AK 1TWAA 2JA7C 3G4CA 1TWCK 2A69A 4GTFA 3DXJA 2NVQC 3RZOK 1Y1VK 4A3GK 2YU9K 4XLPA 4PAAA 2JA6K 5C4JC 3GTGK 4A93K 5DM6S 2V6SA 1Y1WA 3S1QK 1WQHA 2RGRA 4Q5SA 1WOPA 1XZQB 3FKIK 5IOTA 3TFIA 3T00A 1I50A 4QJVB 5IYCK 3S15C 2VUMK 1R9TK 3H3VL 3T01A 3S1NK 2A68A 4OINA 1EFWA 1TWHC 4OIRA 1FEUA 3G4AA 1YNJA 1INNA 1IBAA 4LK1A 4GFQA 2R93A 5C4XK 2KXYA 3H3VD 4GT9A 1XXBA 5IYDC 4BY7K 5C44K 2JA5K 2E2IK 2JA7A 3HKZL 5IP9C 1DCOA 2EBBA 3S2HK 4C3HK 1O26A 4G0VA 4BBRK 4ILDA 4A3MK 1F7VA 1X31C 4A3LK 3HKZD 4BY1C 2NVYK 2E2HK 2GSUA 4C45A 1ZVUA 3S14C 3HOWK 2B63C 3GTOK 1HI9A 1VLOA 4WFAS 5M5WK 3PO2K 1USMA 2KWAA 3HOXC 4WILA 1TWHA 4AH6A 4KM8A 1WIHA 4KM9A 1YX2A 1AB4A 1IS1A 4WFNS 5JVOA 5M3FK 3HOVK 2R92A 2E2JC 3BUEA 1SMYA 4LJZA 2GSNA 4KASA 4RMFA 1PJ6A 2NVXC 2L3UA 3ERED 4OIOA 2L5NA 5TMCA 1IQ0A 4A3KK 3AD9C 3PIPS 5IP7C 4KN4A 4WJ4A 3LAPA 3LAJA 1JVIA 2CFAA 1WCMC 4M1XA 5HL7S 3N0BA 1K83K 3S17C 2B63A 1ZYRA 4C3IK 1F9NA 3GEIA 1YNNA 4C2MK 5EGHA 1USOA 3NUHA 3GTQC
chains in the Genus database with same CATH topology
3I4NC 3S2DC 4C3IC 2R92C 2JA6K 3S15K 5D4DA 5C4JC 3HOUK 3GTGK 3CQZC 3HOVC 4A93K 4A3DK 4X6AC 3S1QK 4C2MC 4YG2A 4Y52C 4Q5SA 3S1MC 4A3JK 3FKIK 1SFOK 4YFKA 4A3GC 3HOZC 3RZOC 1Y1VC 4G7ZA 4A3JC 4A3CC 1XPPA 1BDFA 4LLGA 3H0GK 4QJVB 3GTJC 3HOWC 5IYCK 3GTLK 3I4MK 2JA6C 3S15C 4A3IK 4BBSK 4QIWL 2VUMK 3GTGC 1R9TK 5IYDK 4KN7A 4A93C 1TWAK 3PO3K 3H3VL 3HOYK 3S1NK 3S1QC 2A68A 1I6VA 4QJVA 4OINA 5M3MK 1TWHC 2PPBA 4OIRA 5TMFA 1YNJA 3FKIC 1SFOC 4A3BK 3GTPC 3GTJK 5M5YK 4LK1A 3H0GC 3S16K 3GTLC 2WAQL 5C4XK 2BE5A 4YFXA 5IYBK 4NOIA 4A3IC 3H3VD 2VUMC 1TWGK 4GZYA 5IYDC 3PO3C 2O5IA 4C3JK 3S1NC 4BY7K 5C44K 2JA5K 2E2IK 4BY1K 2JA8K 1TWCC 4A3BC 4ZH4A 2WAQD 3HKZL 5IP9C 3S2HK 3S14K 3S16C 4C3HK 2B63K 4OIQA 2YU9C 5C4XC 4BBRK 5IYBC 4A3MK 3RZDK 1IW7A 1TWGC 4XSZA 4BXXK 4MEXA 5IP7K 3HOUC 4C3JC 4BY7C 4A3DC 4A3LK 5C44C 2JA5C 3HKZD 2E2IC 4BY1C 3HOXK 2JA8C 2NVYK 3S1RK 2E2HK 2A6EA 2R93K 4KMUA 3S2HC 3S14C 3HOWK 3RZDC 2B63C 2WB1L 4BBRC 4A3MC 4MQ9A 3GTOK 5IYCC 3I4MC 4BBSC 5M5WK 4BXXC 2A6HA 1Y1WK 3PO2K 1R9TC 3GTKK 1TWAC 2E2JK 4LK0A 2PA8L 3HOYC 2NVTK 3HOXC 5C3EK 3M3YK 2NVYC 4G7HA 2E2HC 2NVQK 3M4OK 5FJ8K 2WB1D 2NVXK 1I50K 3I4NK 3S2DK 1K83C 3GTOC 3HOVK 5M3FK 2PA8D 1Y1WC 4JK1A 4A3FK 4YFNA 3GTKC 4G7OA 2E2JC 2Y0SL 1I6HK 4XSXA 1SMYA 5FLMK 4LJZA 3S1MK 2NVTC 5C3EC 3M3YC 3M4OC 1WCMK 5M5XK 4A3CK 2NVXC 3GTMK 1I50C 2R7ZK 3WODA 1I3QK 4Y7NK 4A3EK 3S17K 3EQLA 4C3HC 4OIOA 5TMCA 2Y0SD 4A3FC 4A3KK 5IP7C 1I6HC 1TWFK 5FLMC 1TWHK 3K7AK 4KN4A 4Q4ZA 2PMZL 2JA7K 4A3LC 1HQMA 4MEYA 4XLNA 3GTPK 1WCMC 3S1RC 3GTMC 2R7ZC 1I3QC 4Y7NC 4A3EC 2R93C 2O5JA 1K83K 3GTQK 3S17C 1ZYRA 4AYBL 4C3IK 2R92K 5C4JK 3CQZK 2PMZD 4A3KC 3PO2C 4X6AK 1TWFC 2CW0A 1YNNA 3K7AC 4C2MK 2JA7C 4Y52K 1TWCK 2A69A 5IP9K 3DXJA 2NVQC 3HOZK 4QIWD 4AYBD 1Y1VK 3RZOK 2YU9K 4A3GK 4XLPA 4OIPA 3GTQC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I4N C;  3S2D C;  4C3I C;  2R92 C;  2JA6 K;  3S15 K;  5D4D A;  5C4J C;  3HOU K;  3GTG K;  3CQZ C;  3HOV C;  4A93 K;  4A3D K;  4X6A C;  3S1Q K;  4C2M C;  4YG2 A;  4Y52 C;  4Q5S A;  3S1M C;  4A3J K;  3FKI K;  1SFO K;  4YFK A;  4A3G C;  3HOZ C;  3RZO C;  1Y1V C;  4G7Z A;  4A3J C;  4A3C C;  1XPP A;  1BDF A;  4LLG A;  3H0G K;  4QJV B;  3GTJ C;  3HOW C;  5IYC K;  3GTL K;  3I4M K;  2JA6 C;  3S15 C;  4A3I K;  4BBS K;  4QIW L;  2VUM K;  3GTG C;  1R9T K;  5IYD K;  4KN7 A;  4A93 C;  1TWA K;  3PO3 K;  3H3V L;  3HOY K;  3S1N K;  3S1Q C;  2A68 A;  1I6V A;  4QJV A;  4OIN A;  5M3M K;  1TWH C;  2PPB A;  4OIR A;  5TMF A;  1YNJ A;  3FKI C;  1SFO C;  4A3B K;  3GTP C;  3GTJ K;  5M5Y K;  4LK1 A;  3H0G C;  3S16 K;  3GTL C;  2WAQ L;  5C4X K;  2BE5 A;  4YFX A;  5IYB K;  4NOI A;  4A3I C;  3H3V D;  2VUM C;  1TWG K;  4GZY A;  5IYD C;  3PO3 C;  2O5I A;  4C3J K;  3S1N C;  4BY7 K;  5C44 K;  2JA5 K;  2E2I K;  4BY1 K;  2JA8 K;  1TWC C;  4A3B C;  4ZH4 A;  2WAQ D;  3HKZ L;  5IP9 C;  3S2H K;  3S14 K;  3S16 C;  4C3H K;  2B63 K;  4OIQ A;  2YU9 C;  5C4X C;  4BBR K;  5IYB C;  4A3M K;  3RZD K;  1IW7 A;  1TWG C;  4XSZ A;  4BXX K;  4MEX A;  5IP7 K;  3HOU C;  4C3J C;  4BY7 C;  4A3D C;  4A3L K;  5C44 C;  2JA5 C;  3HKZ D;  2E2I C;  4BY1 C;  3HOX K;  2JA8 C;  2NVY K;  3S1R K;  2E2H K;  2A6E A;  2R93 K;  4KMU A;  3S2H C;  3S14 C;  3HOW K;  3RZD C;  2B63 C;  2WB1 L;  4BBR C;  4A3M C;  4MQ9 A;  3GTO K;  5IYC C;  3I4M C;  4BBS C;  5M5W K;  4BXX C;  2A6H A;  1Y1W K;  3PO2 K;  1R9T C;  3GTK K;  1TWA C;  2E2J K;  4LK0 A;  2PA8 L;  3HOY C;  2NVT K;  3HOX C;  5C3E K;  3M3Y K;  2NVY C;  4G7H A;  2E2H C;  2NVQ K;  3M4O K;  5FJ8 K;  2WB1 D;  2NVX K;  1I50 K;  3I4N K;  3S2D K;  1K83 C;  3GTO C;  3HOV K;  5M3F K;  2PA8 D;  1Y1W C;  4JK1 A;  4A3F K;  4YFN A;  3GTK C;  4G7O A;  2E2J C;  2Y0S L;  1I6H K;  4XSX A;  1SMY A;  5FLM K;  4LJZ A;  3S1M K;  2NVT C;  5C3E C;  3M3Y C;  3M4O C;  1WCM K;  5M5X K;  4A3C K;  2NVX C;  3GTM K;  1I50 C;  2R7Z K;  3WOD A;  1I3Q K;  4Y7N K;  4A3E K;  3S17 K;  3EQL A;  4C3H C;  4OIO A;  5TMC A;  2Y0S D;  4A3F C;  4A3K K;  5IP7 C;  1I6H C;  1TWF K;  5FLM C;  1TWH K;  3K7A K;  4KN4 A;  4Q4Z A;  2PMZ L;  2JA7 K;  4A3L C;  1HQM A;  4MEY A;  4XLN A;  3GTP K;  1WCM C;  3S1R C;  3GTM C;  2R7Z C;  1I3Q C;  4Y7N C;  4A3E C;  2R93 C;  2O5J A;  1K83 K;  3GTQ K;  3S17 C;  1ZYR A;  4AYB L;  4C3I K;  2R92 K;  5C4J K;  3CQZ K;  2PMZ D;  4A3K C;  3PO2 C;  4X6A K;  1TWF C;  2CW0 A;  1YNN A;  3K7A C;  4C2M K;  2JA7 C;  4Y52 K;  1TWC K;  2A69 A;  5IP9 K;  3DXJ A;  2NVQ C;  3HOZ K;  4QIW D;  4AYB D;  1Y1V K;  3RZO K;  2YU9 K;  4A3G K;  4XLP A;  4OIP A;  3GTQ C; 
#chains in the Genus database with same CATH topology
 3BP3 A;  2PHC B;  5L46 A;  3CQZ C;  3AD7 C;  1XXA A;  4A3D K;  4GTC A;  4X6A C;  1O2B A;  4YG2 A;  3AQP A;  3IPJ A;  3S1M C;  1SFO K;  4DDQ A;  1XPP A;  4A3G C;  3RZO C;  1Y1V C;  4G7Z A;  1IE0 A;  3ORE A;  5M5Y K;  3RZD K;  2ZJP S;  4KAR A;  4BLA A;  2NVX A;  3GTL K;  2JA6 C;  4A3I K;  4BBS K;  3GTG C;  4KN7 A;  4A93 C;  1TWA K;  3T02 A;  3GEH A;  2XCQ A;  3HOY K;  3PO3 K;  3SZZ A;  3S1Q C;  1C0A A;  1I6V A;  2W7V A;  2ZUE A;  3FKI C;  1DCP A;  1WCM A;  2P8T A;  4BKW A;  4U67 S;  2BE5 A;  4YFX A;  5IYB K;  1WOR A;  2VUM C;  3S1N C;  2KQ1 A;  5IOR A;  2JA8 K;  4ZH4 A;  2V6U A;  4FM9 A;  1EK8 A;  4WJ3 M;  4OIQ A;  5C4X C;  4O2D A;  3SZY A;  4MEX A;  4BXX K;  3HOU C;  3CQZ A;  4BY7 C;  1WOO A;  3CAG A;  1VRQ C;  5C44 C;  2JA5 C;  2E2I C;  1O24 A;  3S1R K;  4KC6 A;  2R93 K;  4KMU A;  3S2H C;  1VGX A;  3GDZ A;  4P9S A;  2WB1 L;  4BBR C;  4A3M C;  2R7Z A;  3I4M C;  2JA6 A;  3GTG A;  3TFH A;  3GTK K;  2NVT K;  5C3E K;  1WSR A;  3M3Y K;  2NVY C;  2E2H C;  2NVQ K;  3FKI A;  3M4O K;  2WB1 D;  2GAG C;  3TFJ A;  5TJ3 A;  2Y3P A;  3GTO C;  2KPU A;  2XCO A;  4A3F K;  3ADA C;  2Y0S L;  1I6H K;  1J6V A;  1GE9 A;  1EI6 A;  3GTM K;  1I3Q K;  4Y7N K;  2V6T A;  5DM7 S;  5CHP A;  2Y0S D;  2CFA B;  3V4G A;  1TWF K;  2P5M A;  1TWH K;  3K7A K;  2JA5 A;  2E2I A;  4XLN A;  5IOQ A;  2R92 K;  3CF5 S;  4GTL A;  4A3K C;  4KAT A;  4Y52 K;  1B4B A;  1WQF A;  3OPF A;  5IP9 K;  1DD5 A;  2NVY A;  2E2H A;  3HOZ K;  4QIW D;  1XZP A;  4A3J K;  1K83 C;  4OIP A;  2XCR B;  1BJT A;  3I4N C;  3S2D C;  4C3I C;  4GTD A;  3GTO A;  5D4D A;  2JH3 A;  1ZXO A;  4C2M C;  3GEE A;  2D6F C;  4LOW A;  3FOF A;  4A3C C;  1BDF A;  3H0G K;  3GTJ C;  3HOW C;  3FOE A;  4P5A A;  5HL8 A;  4KMD A;  3N0C A;  5TMF A;  1SFO C;  3L4K A;  4A3B K;  3GTP C;  3GTJ K;  3S16 K;  3GTL C;  4NOI A;  4A3I C;  1PJ7 A;  1TWG K;  4GZY A;  3PO3 C;  4C3J K;  4G0W A;  3AD8 C;  1TWC C;  4KMA A;  4LQY A;  4XCH A;  4GTE A;  2YU9 C;  3OEP A;  3GSI A;  5IYB C;  2RH6 A;  1K83 A;  4KB4 A;  1IW7 A;  1J98 A;  5IP7 K;  4BLB A;  1ZBS A;  4KB2 A;  1UV7 A;  2JA8 C;  4IOA S;  1L0W A;  1J6X A;  2GAH C;  1JOE A;  5IYC C;  1BGW A;  5E68 A;  4BXX C;  2A6H A;  1WSV A;  1Y1W K;  1R9T C;  4G7H A;  1ISE A;  1SFO A;  5FJ8 K;  1I50 K;  3GTP A;  5JVH S;  3GTL A;  3QX3 A;  3GTQ A;  2ZFZ A;  3BP8 C;  4JK1 A;  3GTK C;  4G7O A;  5FLM K;  1VH2 A;  3S1M K;  4G0U A;  2NVT C;  5C3E C;  1ZQ1 C;  3M3Y C;  3M4O C;  1TWC A;  2R7Z K;  3WOD A;  4A3E K;  1Y1V A;  4C3H C;  2YU9 A;  1KQ4 A;  4A3F C;  1I6H C;  3A8I A;  2JA7 K;  2PMZ L;  1BS2 A;  4A3L C;  4MEY A;  3GTM C;  2FQO A;  1I3Q C;  4Y7N C;  4GTB A;  4IOC S;  4IO9 S;  4AYB L;  3AQO A;  5C4J K;  1XXC A;  2PMZ D;  1XZP B;  3PO2 C;  2VUM A;  1TWF C;  2CW0 A;  1R9T A;  3K7A C;  3HXA A;  4AYB D;  3MML B;  1O25 A;  2R92 C;  3S15 K;  4WFB S;  3HOU K;  3HOV C;  4WF9 S;  1V5V A;  1J6W A;  3GTK A;  4Y52 C;  1B4A A;  4YFK A;  3HOZ C;  4A3J C;  4LLG A;  1O2F B;  4KDD A;  3I4M K;  5JFE A;  1XZQ A;  4QIW L;  1DCH A;  5IYD K;  3S0X A;  5CJ9 A;  3PIO S;  1YCL A;  4QJV A;  5M3M K;  4WCE S;  2PPB A;  2ZUF A;  3GTM A;  3H0G C;  1I3Q A;  2WAQ L;  1F93 A;  4J3N A;  1JQW A;  4GTA A;  2O5I A;  3AH5 A;  1IL2 A;  3A8J A;  1TWF A;  4BY1 K;  4A3B C;  2WAQ D;  3N3Y A;  3FHZ A;  3S16 C;  3S14 K;  2B63 K;  1WQG A;  4FZB A;  1TWG C;  4XSZ A;  4C3J C;  4A3D C;  3GIR A;  4KMH A;  4PAB A;  3HOX K;  4P5B A;  2A6E A;  3RZD C;  4MQ9 A;  4BBS C;  1VJE A;  3A8K A;  1TWA C;  2E2J K;  4LK0 A;  2PA8 L;  3HOY C;  1O27 A;  3DLL S;  2NVX K;  3LPX A;  3I4N K;  3L4J A;  3S2D K;  1O28 A;  3H0G A;  1F7U A;  2GSO A;  1PJ5 A;  3VA7 A;  2PA8 D;  1Y1W C;  1G51 A;  4YFN A;  4XSX A;  3JST A;  1EQR A;  3TTG A;  1WCM K;  5M5X K;  4A3C K;  1EH1 A;  1I50 C;  3S17 K;  3Q3Q A;  3EQL A;  2ZJR S;  5JVG S;  3GTJ A;  1TWG A;  2FQT A;  5HQH A;  5EGE A;  5FLM C;  4Q4Z A;  1O29 A;  1O2A A;  1RU0 A;  1HQM A;  4KAW X;  3GTP K;  3S1R C;  3LYW A;  2R7Z C;  4A3E C;  2R93 C;  2O5J A;  3GTQ K;  2ZJQ S;  4LR2 A;  3CQZ K;  1WOS A;  5IOS A;  4X6A K;  1TWA A;  2JA7 C;  3G4C A;  1TWC K;  2A69 A;  4GTF A;  3DXJ A;  2NVQ C;  3RZO K;  1Y1V K;  4A3G K;  2YU9 K;  4XLP A;  4PAA A;  2JA6 K;  5C4J C;  3GTG K;  4A93 K;  5DM6 S;  2V6S A;  1Y1W A;  3S1Q K;  1WQH A;  2RGR A;  4Q5S A;  1WOP A;  1XZQ B;  3FKI K;  5IOT A;  3TFI A;  3T00 A;  1I50 A;  4QJV B;  5IYC K;  3S15 C;  2VUM K;  1R9T K;  3H3V L;  3T01 A;  3S1N K;  2A68 A;  4OIN A;  1EFW A;  1TWH C;  4OIR A;  1FEU A;  3G4A A;  1YNJ A;  1INN A;  1IBA A;  4LK1 A;  4GFQ A;  2R93 A;  5C4X K;  2KXY A;  3H3V D;  4GT9 A;  1XXB A;  5IYD C;  4BY7 K;  5C44 K;  2JA5 K;  2E2I K;  2JA7 A;  3HKZ L;  5IP9 C;  1DCO A;  2EBB A;  3S2H K;  4C3H K;  1O26 A;  4G0V A;  4BBR K;  4ILD A;  4A3M K;  1F7V A;  1X31 C;  4A3L K;  3HKZ D;  4BY1 C;  2NVY K;  2E2H K;  2GSU A;  4C45 A;  1ZVU A;  3S14 C;  3HOW K;  2B63 C;  3GTO K;  1HI9 A;  1VLO A;  4WFA S;  5M5W K;  3PO2 K;  1USM A;  2KWA A;  3HOX C;  4WIL A;  1TWH A;  4AH6 A;  4KM8 A;  1WIH A;  4KM9 A;  1YX2 A;  1AB4 A;  1IS1 A;  4WFN S;  5JVO A;  5M3F K;  3HOV K;  2R92 A;  2E2J C;  3BUE A;  1SMY A;  4LJZ A;  2GSN A;  4KAS A;  4RMF A;  1PJ6 A;  2NVX C;  2L3U A;  3ERE D;  4OIO A;  2L5N A;  5TMC A;  1IQ0 A;  4A3K K;  3AD9 C;  3PIP S;  5IP7 C;  4KN4 A;  4WJ4 A;  3LAP A;  3LAJ A;  1JVI A;  2CFA A;  1WCM C;  4M1X A;  5HL7 S;  3N0B A;  1K83 K;  3S17 C;  2B63 A;  1ZYR A;  4C3I K;  1F9N A;  3GEI A;  1YNN A;  4C2M K;  5EGH A;  1USO A;  3NUH A;  3GTQ C; 
#chains in the Genus database with same CATH homology
 3I4N C;  3S2D C;  4C3I C;  2R92 C;  2JA6 K;  3S15 K;  5D4D A;  5C4J C;  3HOU K;  3GTG K;  3CQZ C;  3HOV C;  4A93 K;  4A3D K;  4X6A C;  3S1Q K;  4C2M C;  4YG2 A;  4Y52 C;  4Q5S A;  3S1M C;  4A3J K;  3FKI K;  1SFO K;  4YFK A;  4A3G C;  3HOZ C;  3RZO C;  1Y1V C;  4G7Z A;  4A3J C;  4A3C C;  1XPP A;  1BDF A;  4LLG A;  3H0G K;  4QJV B;  3GTJ C;  3HOW C;  5IYC K;  3GTL K;  3I4M K;  2JA6 C;  3S15 C;  4A3I K;  4BBS K;  4QIW L;  2VUM K;  3GTG C;  1R9T K;  5IYD K;  4KN7 A;  4A93 C;  1TWA K;  3PO3 K;  3H3V L;  3HOY K;  3S1N K;  3S1Q C;  2A68 A;  1I6V A;  4QJV A;  4OIN A;  5M3M K;  1TWH C;  2PPB A;  4OIR A;  5TMF A;  1YNJ A;  3FKI C;  1SFO C;  4A3B K;  3GTP C;  3GTJ K;  5M5Y K;  4LK1 A;  3H0G C;  3S16 K;  3GTL C;  2WAQ L;  5C4X K;  2BE5 A;  4YFX A;  5IYB K;  4NOI A;  4A3I C;  3H3V D;  2VUM C;  1TWG K;  4GZY A;  5IYD C;  3PO3 C;  2O5I A;  4C3J K;  3S1N C;  4BY7 K;  5C44 K;  2JA5 K;  2E2I K;  4BY1 K;  2JA8 K;  1TWC C;  4A3B C;  4ZH4 A;  2WAQ D;  3HKZ L;  5IP9 C;  3S2H K;  3S14 K;  3S16 C;  4C3H K;  2B63 K;  4OIQ A;  2YU9 C;  5C4X C;  4BBR K;  5IYB C;  4A3M K;  3RZD K;  1IW7 A;  1TWG C;  4XSZ A;  4BXX K;  4MEX A;  5IP7 K;  3HOU C;  4C3J C;  4BY7 C;  4A3D C;  4A3L K;  5C44 C;  2JA5 C;  3HKZ D;  2E2I C;  4BY1 C;  3HOX K;  2JA8 C;  2NVY K;  3S1R K;  2E2H K;  2A6E A;  2R93 K;  4KMU A;  3S2H C;  3S14 C;  3HOW K;  3RZD C;  2B63 C;  2WB1 L;  4BBR C;  4A3M C;  4MQ9 A;  3GTO K;  5IYC C;  3I4M C;  4BBS C;  5M5W K;  4BXX C;  2A6H A;  1Y1W K;  3PO2 K;  1R9T C;  3GTK K;  1TWA C;  2E2J K;  4LK0 A;  2PA8 L;  3HOY C;  2NVT K;  3HOX C;  5C3E K;  3M3Y K;  2NVY C;  4G7H A;  2E2H C;  2NVQ K;  3M4O K;  5FJ8 K;  2WB1 D;  2NVX K;  1I50 K;  3I4N K;  3S2D K;  1K83 C;  3GTO C;  3HOV K;  5M3F K;  2PA8 D;  1Y1W C;  4JK1 A;  4A3F K;  4YFN A;  3GTK C;  4G7O A;  2E2J C;  2Y0S L;  1I6H K;  4XSX A;  1SMY A;  5FLM K;  4LJZ A;  3S1M K;  2NVT C;  5C3E C;  3M3Y C;  3M4O C;  1WCM K;  5M5X K;  4A3C K;  2NVX C;  3GTM K;  1I50 C;  2R7Z K;  3WOD A;  1I3Q K;  4Y7N K;  4A3E K;  3S17 K;  3EQL A;  4C3H C;  4OIO A;  5TMC A;  2Y0S D;  4A3F C;  4A3K K;  5IP7 C;  1I6H C;  1TWF K;  5FLM C;  1TWH K;  3K7A K;  4KN4 A;  4Q4Z A;  2PMZ L;  2JA7 K;  4A3L C;  1HQM A;  4MEY A;  4XLN A;  3GTP K;  1WCM C;  3S1R C;  3GTM C;  2R7Z C;  1I3Q C;  4Y7N C;  4A3E C;  2R93 C;  2O5J A;  1K83 K;  3GTQ K;  3S17 C;  1ZYR A;  4AYB L;  4C3I K;  2R92 K;  5C4J K;  3CQZ K;  2PMZ D;  4A3K C;  3PO2 C;  4X6A K;  1TWF C;  2CW0 A;  1YNN A;  3K7A C;  4C2M K;  2JA7 C;  4Y52 K;  1TWC K;  2A69 A;  5IP9 K;  3DXJ A;  2NVQ C;  3HOZ K;  4QIW D;  4AYB D;  1Y1V K;  3RZO K;  2YU9 K;  4A3G K;  4XLP A;  4OIP A;  3GTQ C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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