4XSXA

Crystal structure of cbr 703 bound to escherichia coli rna polymerase holoenzyme
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
224
structure length
224
Chain Sequence
FLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAF
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase subunit alpha
publication title CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
pubmed doi rcsb
source organism Escherichia coli (strain k12)
molecule tags Transcription/antibiotic
total genus 42
structure length 224
sequence length 224
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4xsxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4xsxA01
2NVQC 3RZOC 3DXJA 4A3EK 2JA5C 4C3HC 4KN4A 3S16K 5C4XC 4BBRC 2NVXC 3HOXC 3M3YC 4YFKA 3HOYK 3S2HK 2VUMK 2PA8L 3HKZD 5FLMC 2A68A 4A93C 5IYBK 2PA8D 4Y52C 3K7AK 2R92K 3S1QC 4A3DC 5IYDK 5C4JC 1TWCK 4QJVB 4QJVA 1I3QK 4BY7K 4QIWD 2JA8C 4BBSK 3M4OK 4A3IC 4XLNA 4A3BC 1I50C 4LK1A 4C3IC 4C2MC 4G7HA 4BY1K 4A3LK 3GTOC 4YFXA 1R9TK 3S1MK 3GTJK 3GTLC 1Y1WC 1I6HC 3S1NC 4C3JK 5IP7K 3EQLA 4YG2A 4A3MC 2B63K 3HOWK 4A3KK 4Y7NK 2NVQK 3RZOK 2A6HA 1K83C 3H0GK 2E2IC 3S1RC 2R7ZK 2JA5K 3HOVC 4KMUA 2NVXK 3GTKK 3M3YK 2O5IA 2JA7C 3GTGK 2WAQD 5C3EC 3PO3C 1WCMK 2NVTK 3PO2C 3HKZL 4A93K 4XLPA 2NVYC 1I6VA 3I4NC 4G7OA 5C44C 2JA6C 2E2JK 5M5YK 3HOZK 4A3FK 4OIQA 3S15C 4BXXC 4QIWL 4A3GC 1TWFC 4AYBD 3GTMC 1HQMA 2A6EA 4A3IK 4MEYA 1BDFA 1I50K 4C2MK 4C3IK 3S17K 5IYCC 1Y1VK 3CQZC 5IP9K 4JK1A 3HOUC 1Y1WK 1I6HK 4X6AC 1XPPA 3S1NK 2Y0SD 4G7ZA 2O5JA 2CW0A 4A3MK 3S2DK 5FJ8K 3I4MC 5M5XK 4MEXA 1K83K 2E2IK 4YFNA 3RZDC 2R93K 2R93C 3HOVK 1ZYRA 2WAQL 2A69A 4C3HK 2JA7K 2B63C 5C4XK 3GTQC 4BBRK 3HOXK 3PO3K 3PO2K 5M5WK 4OINA 5M3FK 3GTPC 2NVYK 1TWAC 2PMZL 5C44K 5IYDC 5FLMK 2JA6K 1TWGC 3FKIC 4Y52K 1TWCC 4A3CC 3S1QK 4A3DK 2PMZD 2E2HC 5C4JK 4ZH4A 4AYBL 3S15K 4A3GK 1TWFK 3M4OC 4OIRA 1TWHC 4BY1C 2JA8K 2YU9C 4A3BK 5IYCK 3S1MC 1SFOK 5TMCA 3GTOK 2Y0SL 4XSXA 5IP7C 3GTLK 2WB1D 2BE5A 3S14C 1IW7A 4LLGA 4GZYA 1YNNA 4Q4ZA 4A3JC 3H0GC 1SFOC 3I4MK 2R7ZC 3HOWC 3RZDK 4A3EC 3S1RK 3WODA 3GTGC 3S16C 3HOYC 1WCMC 2NVTC 3S2HC 2PPBA 3GTQK 5TMFA 2VUMC 5C3EK 3GTPK 1SMYA 1TWAK 2E2JC 5IYBC 3GTKC 3HOZC 4A3FC 1TWGK 3FKIK 3K7AC 2R92C 4KN7A 3I4NK 4A3CK 2E2HK 5M3MK 4NOIA 4OIOA 4LK0A 4BXXK 3H3VL 1I3QC 4BY7C 4BBSC 1TWHK 3S17C 4A3LC 3GTMK 4Q5SA 2YU9K 3H3VD 1Y1VC 5IP9C 1R9TC 4XSZA 4LJZA 3CQZK 3GTJC 2WB1L 3HOUK 3S2DC 1YNJA 4OIPA 4C3JC 4X6AK 3S14K 5D4DA 4A3JK 4MQ9A 4A3KC 4Y7NC
chains in the Genus database with same CATH superfamily
3DXJA 1BS2A 3T00A 4DDQA 3S16K 2NVXC 3HOXC 5JVHS 4YFKA 2VUMK 2GSOA 2ZJQS 5IYBK 4Y52C 5DM6S 2R92K 5IYDK 1DD5A 2JA8C 4BBSK 1WSRA 4A3LK 4G7HA 2GSUA 3GTPA 1R9TK 1TWGA 2CFAB 3GTJK 1TWCA 2CFAA 2W7VA 4C3JK 3N0CA 5HL7S 3HOWK 4A3KK 4IOAS 3AQOA 4GTAA 5E68A 3GEIA 2NVQK 3DLLS 5IOSA 3S1RC 5L46A 3PIOS 2XCOA 4BLAA 2JA7C 3GTGK 3PO3C 2B63A 1X31C 2KXYA 1SFOA 2GAGC 4G7OA 5C44C 2R7ZA 1DCHA 3IPJA 5IOTA 3AH5A 1HQMA 2VUMA 4A3IK 4C2MK 4C3IK 4FZBA 3GEHA 3CQZC 4JK1A 2R92A 3HOUC 1XPPA 3VA7A 1PJ5A 4G7ZA 1XZQB 1Y1VA 2XCQA 1XZQA 2R93C 1B4BA 1R9TA 3GTJA 2A69A 2KPUA 5C4XK 3GTQC 4BBRK 5M5WK 5HQHA 3NUHA 1ZXOA 2P5MA 1TWAC 1WOSA 3S1QK 2PMZD 2P8TA 4P5AA 4A3GK 1EI6A 5JVOA 2YU9C 4A3BK 2JH3A 1F7UA 3TFJA 1ZBSA 3GTOK 3GTLK 3G4AA 4LLGA 4GFQA 1JQWA 1UV7A 2ZUFA 3HOYC 1WCMC 2NVTC 4IO9S 3GDZA 5C3EK 1G51A 2E2JC 3FKIK 3K7AC 3I4NK 1ZVUA 4LK0A 4GTBA 3GTMK 1TWHK 3LYWA 4Q5SA 5DM7S 4WFNS 3H3VD 3TFIA 1IE0A 5IP9C 1B4AA 2WB1L 5EGHA 3S2DC 1O28A 4Y7NC 3RZOC 3CAGA 3N0BA 4WFBS 4C3HC 1IS1A 1DCPA 3M3YC 4WJ4A 2PA8L 4A93C 2A68A 4KM8A 4A3DC 5C4JC 1TWCK 1EQRA 3FOFA 2ZJRS 1O29A 3M4OK 1YCLA 4J3NA 1I50C 4M1XA 4YFXA 3S1MK 3FKIA 1INNA 1Y1WC 3S1NC 3EQLA 4YG2A 4A3MC 2B63K 2V6TA 1JOEA 1TWHA 1K83C 3FHZA 2E2IC 2R7ZK 1GE9A 4KMUA 2NVXK 3PO2C 3H0GA 3CF5S 2NVYC 2JA6C 4GTFA 4GT9A 4A3FK 3HOZK 1VH2A 3BP8C 4ILDA 3S15C 4BXXC 4PAAA 5IOQA 3S17K 5IYCC 1Y1VK 3PIPS 2CW0A 1WQGA 4YFNA 1VRQC 2WAQL 4LQYA 2JA7K 4GTLA 3PO3K 1WIHA 1O27A 4OINA 4KB4A 5C44K 5IYDC 5FLMK 2E2HC 4AYBL 2NVXA 1F93A 1O2FB 3S0XA 1DCOA 3MMLB 5TMCA 2KQ1A 1FEUA 2WB1D 2BE5A 3S14C 4A3EC 1J6XA 3GTGC 3GTQK 3S2HC 3T02A 2PPBA 3Q3QA 1O2AA 1TWAK 3GTKC 4KB2A 2ZFZA 5M3MK 2JA7A 1I3QC 4BY7C 2YU9K 4WCES 1C0AA 1XXAA 4X6AK 1YNJA 4OIPA 1J98A 4G0WA 4MQ9A 4G0VA 3A8IA 3CQZA 2JA5C 4KDDA 5C4XC 4BBRC 3HOYK 3TTGA 1O25A 5CHPA 4KASA 1WSVA 3TFHA 4BKWA 3K7AK 3S1QC 4WF9S 2R93A 4QJVB 1J6WA 4QJVA 3GTQA 5JVGS 4XLNA 4A3BC 4P5BA 3ERED 4BY1K 1VLOA 1TWAA 3GTOC 2XCRB 1WQHA 3HXAA 2V6SA 3GTLC 1ISEA 1I6HC 1RU0A 3LPXA 3A8KA 5IP7K 3AD7C 4KC6A 1WOPA 4Y7NK 3RZOK 2A6HA 3H0GK 2YU9A 2ZUEA 3OREA 4KMAA 3HOVC 1PJ7A 3M3YK 2O5IA 2WAQD 5C3EC 3HKZL 4KATA 1O26A 4A93K 4XLPA 3I4NC 1XZPA 5M5YK 3FOEA 4QIWL 1WCMA 1TWFC 4AYBD 3GTMC 1WQFA 2A6EA 1ZQ1C 1I50K 1BDFA 1USMA 1Y1WK 3QX3A 3S1NK 1XXCA 4A3MK 1O24A 3JSTA 3I4MC 2EBBA 1K83K 2E2IK 3V4GA 1HI9A 3RZDC 3LAPA 3HOXK 3PO2K 5M3FK 3SZZA 3GTPC 2NVYK 2PMZL 5TJ3A 2JA6K 1TWGC 4WFAS 4WILA 3OPFA 1TWCC 4A3CC 4Y52K 3S15K 4ZH4A 3M4OC 4OIRA 2JA8K 5HL8A 5IYCK 3S1MC 1SFOK 2Y0SL 4XSXA 3OEPA 1KQ4A 1XXBA 1IW7A 4Q4ZA 4A3JC 1SFOC 1VGXA 1I50A 2GSNA 2R7ZC 3N3YA 3S1RK 1Y1WA 3WODA 3S16C 2VUMC 1BJTA 1SMYA 3BP3A 4GTCA 5IYBC 1K83A 3HOZC 4A3FC 2E2IA 3BUEA 2R92C 4PABA 2E2HK 4OIOA 2KWAA 3H3VL 4BBSC 4C45A 3S17C 4A3LC 2RGRA 1Y1VC 2NVYA 2JA6A 1R9TC 4XSZA 4LJZA 3CQZK 3GTJC 3HOUK 4C3JC 3S14K 3HOWC 5D4DA 4A3KC 4KM9A 2NVQC 2RH6A 4A3EK 4KN4A 2R93K 3S2HK 2L5NA 5JFEA 3HKZD 5FLMC 3GTKK 2PA8D 3GSIA 4G0UA 5CJ9A 1IL2A 1I3QK 4BY7K 4QIWD 4A3IC 4LK1A 4C3IC 4C2MC 2V6UA 3AD8C 1USOA 1IBAA 4KMDA 1WORA 2E2HA 2Y3PA 2PHCB 4U67S 4IOCS 2JA5K 4O2DA 2FQOA 4P9SA 1WCMK 2NVTK 1EK8A 4GTDA 1I6VA 2E2JK 1BGWA 4OIQA 3LAJA 3SZYA 3GTGA 4A3GC 1JVIA 1F9NA 4MEYA 3ADAC 4RMFA 3GTKA 5IP9K 1I6HK 4X6AC 2Y0SD 2O5JA 3S2DK 1I3QA 5FJ8K 4KMHA 5M5XK 3AD9C 4MEXA 4GTEA 4BLBA 2GAHC 3HOVK 1ZYRA 4WJ3M 4C3HK 1V5VA 2D6FC 1IQ0A 1VJEA 5EGEA 1XZPB 3FKIC 3L4JA 3AQPA 4FM9A 4A3DK 2JA5A 3GIRA 5C4JK 4KARA 1J6VA 1TWFK 1TWHC 4BY1C 1PJ6A 2L3UA 5IP7C 1WOOA 3G4CA 4GZYA 3I4MK 1YNNA 3H0GC 3T01A 1EH1A 3A8JA 1F7VA 3RZDK 3GTOA 2FQTA 3GTLA 4LOWA 5TMFA 3L4KA 1EFWA 1AB4A 3GTPK 1TWGK 4A3CK 4KN7A 1O2BA 4NOIA 1YX2A 4LR2A 4BXXK 4AH6A 2ZJPS 1L0WA 3GEEA 4KAWX 4XCHA 5IORA 1TWFA 3GTMA 2B63C 4A3JK
chains in the Genus database with same CATH topology
2NVQC 3RZOC 3DXJA 4A3EK 2JA5C 4C3HC 4KN4A 3S16K 5C4XC 4BBRC 2NVXC 3HOXC 3M3YC 4YFKA 3HOYK 3S2HK 2VUMK 2PA8L 3HKZD 5FLMC 2A68A 4A93C 5IYBK 2PA8D 4Y52C 3K7AK 2R92K 3S1QC 4A3DC 5IYDK 5C4JC 1TWCK 4QJVB 4QJVA 1I3QK 4BY7K 4QIWD 2JA8C 4BBSK 3M4OK 4A3IC 4XLNA 4A3BC 1I50C 4LK1A 4C3IC 4C2MC 4G7HA 4BY1K 4A3LK 3GTOC 4YFXA 1R9TK 3S1MK 3GTJK 3GTLC 1Y1WC 1I6HC 3S1NC 4C3JK 5IP7K 3EQLA 4YG2A 4A3MC 2B63K 3HOWK 4A3KK 4Y7NK 2NVQK 3RZOK 2A6HA 1K83C 3H0GK 2E2IC 3S1RC 2R7ZK 2JA5K 3HOVC 4KMUA 2NVXK 3GTKK 3M3YK 2O5IA 2JA7C 3GTGK 2WAQD 5C3EC 3PO3C 1WCMK 2NVTK 3PO2C 3HKZL 4A93K 4XLPA 2NVYC 1I6VA 3I4NC 4G7OA 5C44C 2JA6C 2E2JK 5M5YK 3HOZK 4A3FK 4OIQA 3S15C 4BXXC 4QIWL 4A3GC 1TWFC 4AYBD 3GTMC 1HQMA 2A6EA 4A3IK 4MEYA 1BDFA 1I50K 4C2MK 4C3IK 3S17K 5IYCC 1Y1VK 3CQZC 5IP9K 4JK1A 3HOUC 1Y1WK 1I6HK 4X6AC 1XPPA 3S1NK 2Y0SD 4G7ZA 2O5JA 2CW0A 4A3MK 3S2DK 5FJ8K 3I4MC 5M5XK 4MEXA 1K83K 2E2IK 4YFNA 3RZDC 2R93K 2R93C 3HOVK 1ZYRA 2WAQL 2A69A 4C3HK 2JA7K 2B63C 5C4XK 3GTQC 4BBRK 3HOXK 3PO3K 3PO2K 5M5WK 4OINA 5M3FK 3GTPC 2NVYK 1TWAC 2PMZL 5C44K 5IYDC 5FLMK 2JA6K 1TWGC 3FKIC 4Y52K 1TWCC 4A3CC 3S1QK 4A3DK 2PMZD 2E2HC 5C4JK 4ZH4A 4AYBL 3S15K 4A3GK 1TWFK 3M4OC 4OIRA 1TWHC 4BY1C 2JA8K 2YU9C 4A3BK 5IYCK 3S1MC 1SFOK 5TMCA 3GTOK 2Y0SL 4XSXA 5IP7C 3GTLK 2WB1D 2BE5A 3S14C 1IW7A 4LLGA 4GZYA 1YNNA 4Q4ZA 4A3JC 3H0GC 1SFOC 3I4MK 2R7ZC 3HOWC 3RZDK 4A3EC 3S1RK 3WODA 3GTGC 3S16C 3HOYC 1WCMC 2NVTC 3S2HC 2PPBA 3GTQK 5TMFA 2VUMC 5C3EK 3GTPK 1SMYA 1TWAK 2E2JC 5IYBC 3GTKC 3HOZC 4A3FC 1TWGK 3FKIK 3K7AC 2R92C 4KN7A 3I4NK 4A3CK 2E2HK 5M3MK 4NOIA 4OIOA 4LK0A 4BXXK 3H3VL 1I3QC 4BY7C 4BBSC 1TWHK 3S17C 4A3LC 3GTMK 4Q5SA 2YU9K 3H3VD 1Y1VC 5IP9C 1R9TC 4XSZA 4LJZA 3CQZK 3GTJC 2WB1L 3HOUK 3S2DC 1YNJA 4OIPA 4C3JC 4X6AK 3S14K 5D4DA 4A3JK 4MQ9A 4A3KC 4Y7NC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVQ C;  3RZO C;  3DXJ A;  4A3E K;  2JA5 C;  4C3H C;  4KN4 A;  3S16 K;  5C4X C;  4BBR C;  2NVX C;  3HOX C;  3M3Y C;  4YFK A;  3HOY K;  3S2H K;  2VUM K;  2PA8 L;  3HKZ D;  5FLM C;  2A68 A;  4A93 C;  5IYB K;  2PA8 D;  4Y52 C;  3K7A K;  2R92 K;  3S1Q C;  4A3D C;  5IYD K;  5C4J C;  1TWC K;  4QJV B;  4QJV A;  1I3Q K;  4BY7 K;  4QIW D;  2JA8 C;  4BBS K;  3M4O K;  4A3I C;  4XLN A;  4A3B C;  1I50 C;  4LK1 A;  4C3I C;  4C2M C;  4G7H A;  4BY1 K;  4A3L K;  3GTO C;  4YFX A;  1R9T K;  3S1M K;  3GTJ K;  3GTL C;  1Y1W C;  1I6H C;  3S1N C;  4C3J K;  5IP7 K;  3EQL A;  4YG2 A;  4A3M C;  2B63 K;  3HOW K;  4A3K K;  4Y7N K;  2NVQ K;  3RZO K;  2A6H A;  1K83 C;  3H0G K;  2E2I C;  3S1R C;  2R7Z K;  2JA5 K;  3HOV C;  4KMU A;  2NVX K;  3GTK K;  3M3Y K;  2O5I A;  2JA7 C;  3GTG K;  2WAQ D;  5C3E C;  3PO3 C;  1WCM K;  2NVT K;  3PO2 C;  3HKZ L;  4A93 K;  4XLP A;  2NVY C;  1I6V A;  3I4N C;  4G7O A;  5C44 C;  2JA6 C;  2E2J K;  5M5Y K;  3HOZ K;  4A3F K;  4OIQ A;  3S15 C;  4BXX C;  4QIW L;  4A3G C;  1TWF C;  4AYB D;  3GTM C;  1HQM A;  2A6E A;  4A3I K;  4MEY A;  1BDF A;  1I50 K;  4C2M K;  4C3I K;  3S17 K;  5IYC C;  1Y1V K;  3CQZ C;  5IP9 K;  4JK1 A;  3HOU C;  1Y1W K;  1I6H K;  4X6A C;  1XPP A;  3S1N K;  2Y0S D;  4G7Z A;  2O5J A;  2CW0 A;  4A3M K;  3S2D K;  5FJ8 K;  3I4M C;  5M5X K;  4MEX A;  1K83 K;  2E2I K;  4YFN A;  3RZD C;  2R93 K;  2R93 C;  3HOV K;  1ZYR A;  2WAQ L;  2A69 A;  4C3H K;  2JA7 K;  2B63 C;  5C4X K;  3GTQ C;  4BBR K;  3HOX K;  3PO3 K;  3PO2 K;  5M5W K;  4OIN A;  5M3F K;  3GTP C;  2NVY K;  1TWA C;  2PMZ L;  5C44 K;  5IYD C;  5FLM K;  2JA6 K;  1TWG C;  3FKI C;  4Y52 K;  1TWC C;  4A3C C;  3S1Q K;  4A3D K;  2PMZ D;  2E2H C;  5C4J K;  4ZH4 A;  4AYB L;  3S15 K;  4A3G K;  1TWF K;  3M4O C;  4OIR A;  1TWH C;  4BY1 C;  2JA8 K;  2YU9 C;  4A3B K;  5IYC K;  3S1M C;  1SFO K;  5TMC A;  3GTO K;  2Y0S L;  4XSX A;  5IP7 C;  3GTL K;  2WB1 D;  2BE5 A;  3S14 C;  1IW7 A;  4LLG A;  4GZY A;  1YNN A;  4Q4Z A;  4A3J C;  3H0G C;  1SFO C;  3I4M K;  2R7Z C;  3HOW C;  3RZD K;  4A3E C;  3S1R K;  3WOD A;  3GTG C;  3S16 C;  3HOY C;  1WCM C;  2NVT C;  3S2H C;  2PPB A;  3GTQ K;  5TMF A;  2VUM C;  5C3E K;  3GTP K;  1SMY A;  1TWA K;  2E2J C;  5IYB C;  3GTK C;  3HOZ C;  4A3F C;  1TWG K;  3FKI K;  3K7A C;  2R92 C;  4KN7 A;  3I4N K;  4A3C K;  2E2H K;  5M3M K;  4NOI A;  4OIO A;  4LK0 A;  4BXX K;  3H3V L;  1I3Q C;  4BY7 C;  4BBS C;  1TWH K;  3S17 C;  4A3L C;  3GTM K;  4Q5S A;  2YU9 K;  3H3V D;  1Y1V C;  5IP9 C;  1R9T C;  4XSZ A;  4LJZ A;  3CQZ K;  3GTJ C;  2WB1 L;  3HOU K;  3S2D C;  1YNJ A;  4OIP A;  4C3J C;  4X6A K;  3S14 K;  5D4D A;  4A3J K;  4MQ9 A;  4A3K C;  4Y7N C; 
#chains in the Genus database with same CATH topology
 3DXJ A;  1BS2 A;  3T00 A;  4DDQ A;  3S16 K;  2NVX C;  3HOX C;  5JVH S;  4YFK A;  2VUM K;  2GSO A;  2ZJQ S;  5IYB K;  4Y52 C;  5DM6 S;  2R92 K;  5IYD K;  1DD5 A;  2JA8 C;  4BBS K;  1WSR A;  4A3L K;  4G7H A;  2GSU A;  3GTP A;  1R9T K;  1TWG A;  2CFA B;  3GTJ K;  1TWC A;  2CFA A;  2W7V A;  4C3J K;  3N0C A;  5HL7 S;  3HOW K;  4A3K K;  4IOA S;  3AQO A;  4GTA A;  5E68 A;  3GEI A;  2NVQ K;  3DLL S;  5IOS A;  3S1R C;  5L46 A;  3PIO S;  2XCO A;  4BLA A;  2JA7 C;  3GTG K;  3PO3 C;  2B63 A;  1X31 C;  2KXY A;  1SFO A;  2GAG C;  4G7O A;  5C44 C;  2R7Z A;  1DCH A;  3IPJ A;  5IOT A;  3AH5 A;  1HQM A;  2VUM A;  4A3I K;  4C2M K;  4C3I K;  4FZB A;  3GEH A;  3CQZ C;  4JK1 A;  2R92 A;  3HOU C;  1XPP A;  3VA7 A;  1PJ5 A;  4G7Z A;  1XZQ B;  1Y1V A;  2XCQ A;  1XZQ A;  2R93 C;  1B4B A;  1R9T A;  3GTJ A;  2A69 A;  2KPU A;  5C4X K;  3GTQ C;  4BBR K;  5M5W K;  5HQH A;  3NUH A;  1ZXO A;  2P5M A;  1TWA C;  1WOS A;  3S1Q K;  2PMZ D;  2P8T A;  4P5A A;  4A3G K;  1EI6 A;  5JVO A;  2YU9 C;  4A3B K;  2JH3 A;  1F7U A;  3TFJ A;  1ZBS A;  3GTO K;  3GTL K;  3G4A A;  4LLG A;  4GFQ A;  1JQW A;  1UV7 A;  2ZUF A;  3HOY C;  1WCM C;  2NVT C;  4IO9 S;  3GDZ A;  5C3E K;  1G51 A;  2E2J C;  3FKI K;  3K7A C;  3I4N K;  1ZVU A;  4LK0 A;  4GTB A;  3GTM K;  1TWH K;  3LYW A;  4Q5S A;  5DM7 S;  4WFN S;  3H3V D;  3TFI A;  1IE0 A;  5IP9 C;  1B4A A;  2WB1 L;  5EGH A;  3S2D C;  1O28 A;  4Y7N C;  3RZO C;  3CAG A;  3N0B A;  4WFB S;  4C3H C;  1IS1 A;  1DCP A;  3M3Y C;  4WJ4 A;  2PA8 L;  4A93 C;  2A68 A;  4KM8 A;  4A3D C;  5C4J C;  1TWC K;  1EQR A;  3FOF A;  2ZJR S;  1O29 A;  3M4O K;  1YCL A;  4J3N A;  1I50 C;  4M1X A;  4YFX A;  3S1M K;  3FKI A;  1INN A;  1Y1W C;  3S1N C;  3EQL A;  4YG2 A;  4A3M C;  2B63 K;  2V6T A;  1JOE A;  1TWH A;  1K83 C;  3FHZ A;  2E2I C;  2R7Z K;  1GE9 A;  4KMU A;  2NVX K;  3PO2 C;  3H0G A;  3CF5 S;  2NVY C;  2JA6 C;  4GTF A;  4GT9 A;  4A3F K;  3HOZ K;  1VH2 A;  3BP8 C;  4ILD A;  3S15 C;  4BXX C;  4PAA A;  5IOQ A;  3S17 K;  5IYC C;  1Y1V K;  3PIP S;  2CW0 A;  1WQG A;  4YFN A;  1VRQ C;  2WAQ L;  4LQY A;  2JA7 K;  4GTL A;  3PO3 K;  1WIH A;  1O27 A;  4OIN A;  4KB4 A;  5C44 K;  5IYD C;  5FLM K;  2E2H C;  4AYB L;  2NVX A;  1F93 A;  1O2F B;  3S0X A;  1DCO A;  3MML B;  5TMC A;  2KQ1 A;  1FEU A;  2WB1 D;  2BE5 A;  3S14 C;  4A3E C;  1J6X A;  3GTG C;  3GTQ K;  3S2H C;  3T02 A;  2PPB A;  3Q3Q A;  1O2A A;  1TWA K;  3GTK C;  4KB2 A;  2ZFZ A;  5M3M K;  2JA7 A;  1I3Q C;  4BY7 C;  2YU9 K;  4WCE S;  1C0A A;  1XXA A;  4X6A K;  1YNJ A;  4OIP A;  1J98 A;  4G0W A;  4MQ9 A;  4G0V A;  3A8I A;  3CQZ A;  2JA5 C;  4KDD A;  5C4X C;  4BBR C;  3HOY K;  3TTG A;  1O25 A;  5CHP A;  4KAS A;  1WSV A;  3TFH A;  4BKW A;  3K7A K;  3S1Q C;  4WF9 S;  2R93 A;  4QJV B;  1J6W A;  4QJV A;  3GTQ A;  5JVG S;  4XLN A;  4A3B C;  4P5B A;  3ERE D;  4BY1 K;  1VLO A;  1TWA A;  3GTO C;  2XCR B;  1WQH A;  3HXA A;  2V6S A;  3GTL C;  1ISE A;  1I6H C;  1RU0 A;  3LPX A;  3A8K A;  5IP7 K;  3AD7 C;  4KC6 A;  1WOP A;  4Y7N K;  3RZO K;  2A6H A;  3H0G K;  2YU9 A;  2ZUE A;  3ORE A;  4KMA A;  3HOV C;  1PJ7 A;  3M3Y K;  2O5I A;  2WAQ D;  5C3E C;  3HKZ L;  4KAT A;  1O26 A;  4A93 K;  4XLP A;  3I4N C;  1XZP A;  5M5Y K;  3FOE A;  4QIW L;  1WCM A;  1TWF C;  4AYB D;  3GTM C;  1WQF A;  2A6E A;  1ZQ1 C;  1I50 K;  1BDF A;  1USM A;  1Y1W K;  3QX3 A;  3S1N K;  1XXC A;  4A3M K;  1O24 A;  3JST A;  3I4M C;  2EBB A;  1K83 K;  2E2I K;  3V4G A;  1HI9 A;  3RZD C;  3LAP A;  3HOX K;  3PO2 K;  5M3F K;  3SZZ A;  3GTP C;  2NVY K;  2PMZ L;  5TJ3 A;  2JA6 K;  1TWG C;  4WFA S;  4WIL A;  3OPF A;  1TWC C;  4A3C C;  4Y52 K;  3S15 K;  4ZH4 A;  3M4O C;  4OIR A;  2JA8 K;  5HL8 A;  5IYC K;  3S1M C;  1SFO K;  2Y0S L;  4XSX A;  3OEP A;  1KQ4 A;  1XXB A;  1IW7 A;  4Q4Z A;  4A3J C;  1SFO C;  1VGX A;  1I50 A;  2GSN A;  2R7Z C;  3N3Y A;  3S1R K;  1Y1W A;  3WOD A;  3S16 C;  2VUM C;  1BJT A;  1SMY A;  3BP3 A;  4GTC A;  5IYB C;  1K83 A;  3HOZ C;  4A3F C;  2E2I A;  3BUE A;  2R92 C;  4PAB A;  2E2H K;  4OIO A;  2KWA A;  3H3V L;  4BBS C;  4C45 A;  3S17 C;  4A3L C;  2RGR A;  1Y1V C;  2NVY A;  2JA6 A;  1R9T C;  4XSZ A;  4LJZ A;  3CQZ K;  3GTJ C;  3HOU K;  4C3J C;  3S14 K;  3HOW C;  5D4D A;  4A3K C;  4KM9 A;  2NVQ C;  2RH6 A;  4A3E K;  4KN4 A;  2R93 K;  3S2H K;  2L5N A;  5JFE A;  3HKZ D;  5FLM C;  3GTK K;  2PA8 D;  3GSI A;  4G0U A;  5CJ9 A;  1IL2 A;  1I3Q K;  4BY7 K;  4QIW D;  4A3I C;  4LK1 A;  4C3I C;  4C2M C;  2V6U A;  3AD8 C;  1USO A;  1IBA A;  4KMD A;  1WOR A;  2E2H A;  2Y3P A;  2PHC B;  4U67 S;  4IOC S;  2JA5 K;  4O2D A;  2FQO A;  4P9S A;  1WCM K;  2NVT K;  1EK8 A;  4GTD A;  1I6V A;  2E2J K;  1BGW A;  4OIQ A;  3LAJ A;  3SZY A;  3GTG A;  4A3G C;  1JVI A;  1F9N A;  4MEY A;  3ADA C;  4RMF A;  3GTK A;  5IP9 K;  1I6H K;  4X6A C;  2Y0S D;  2O5J A;  3S2D K;  1I3Q A;  5FJ8 K;  4KMH A;  5M5X K;  3AD9 C;  4MEX A;  4GTE A;  4BLB A;  2GAH C;  3HOV K;  1ZYR A;  4WJ3 M;  4C3H K;  1V5V A;  2D6F C;  1IQ0 A;  1VJE A;  5EGE A;  1XZP B;  3FKI C;  3L4J A;  3AQP A;  4FM9 A;  4A3D K;  2JA5 A;  3GIR A;  5C4J K;  4KAR A;  1J6V A;  1TWF K;  1TWH C;  4BY1 C;  1PJ6 A;  2L3U A;  5IP7 C;  1WOO A;  3G4C A;  4GZY A;  3I4M K;  1YNN A;  3H0G C;  3T01 A;  1EH1 A;  3A8J A;  1F7V A;  3RZD K;  3GTO A;  2FQT A;  3GTL A;  4LOW A;  5TMF A;  3L4K A;  1EFW A;  1AB4 A;  3GTP K;  1TWG K;  4A3C K;  4KN7 A;  1O2B A;  4NOI A;  1YX2 A;  4LR2 A;  4BXX K;  4AH6 A;  2ZJP S;  1L0W A;  3GEE A;  4KAW X;  4XCH A;  5IOR A;  1TWF A;  3GTM A;  2B63 C;  4A3J K; 
#chains in the Genus database with same CATH homology
 2NVQ C;  3RZO C;  3DXJ A;  4A3E K;  2JA5 C;  4C3H C;  4KN4 A;  3S16 K;  5C4X C;  4BBR C;  2NVX C;  3HOX C;  3M3Y C;  4YFK A;  3HOY K;  3S2H K;  2VUM K;  2PA8 L;  3HKZ D;  5FLM C;  2A68 A;  4A93 C;  5IYB K;  2PA8 D;  4Y52 C;  3K7A K;  2R92 K;  3S1Q C;  4A3D C;  5IYD K;  5C4J C;  1TWC K;  4QJV B;  4QJV A;  1I3Q K;  4BY7 K;  4QIW D;  2JA8 C;  4BBS K;  3M4O K;  4A3I C;  4XLN A;  4A3B C;  1I50 C;  4LK1 A;  4C3I C;  4C2M C;  4G7H A;  4BY1 K;  4A3L K;  3GTO C;  4YFX A;  1R9T K;  3S1M K;  3GTJ K;  3GTL C;  1Y1W C;  1I6H C;  3S1N C;  4C3J K;  5IP7 K;  3EQL A;  4YG2 A;  4A3M C;  2B63 K;  3HOW K;  4A3K K;  4Y7N K;  2NVQ K;  3RZO K;  2A6H A;  1K83 C;  3H0G K;  2E2I C;  3S1R C;  2R7Z K;  2JA5 K;  3HOV C;  4KMU A;  2NVX K;  3GTK K;  3M3Y K;  2O5I A;  2JA7 C;  3GTG K;  2WAQ D;  5C3E C;  3PO3 C;  1WCM K;  2NVT K;  3PO2 C;  3HKZ L;  4A93 K;  4XLP A;  2NVY C;  1I6V A;  3I4N C;  4G7O A;  5C44 C;  2JA6 C;  2E2J K;  5M5Y K;  3HOZ K;  4A3F K;  4OIQ A;  3S15 C;  4BXX C;  4QIW L;  4A3G C;  1TWF C;  4AYB D;  3GTM C;  1HQM A;  2A6E A;  4A3I K;  4MEY A;  1BDF A;  1I50 K;  4C2M K;  4C3I K;  3S17 K;  5IYC C;  1Y1V K;  3CQZ C;  5IP9 K;  4JK1 A;  3HOU C;  1Y1W K;  1I6H K;  4X6A C;  1XPP A;  3S1N K;  2Y0S D;  4G7Z A;  2O5J A;  2CW0 A;  4A3M K;  3S2D K;  5FJ8 K;  3I4M C;  5M5X K;  4MEX A;  1K83 K;  2E2I K;  4YFN A;  3RZD C;  2R93 K;  2R93 C;  3HOV K;  1ZYR A;  2WAQ L;  2A69 A;  4C3H K;  2JA7 K;  2B63 C;  5C4X K;  3GTQ C;  4BBR K;  3HOX K;  3PO3 K;  3PO2 K;  5M5W K;  4OIN A;  5M3F K;  3GTP C;  2NVY K;  1TWA C;  2PMZ L;  5C44 K;  5IYD C;  5FLM K;  2JA6 K;  1TWG C;  3FKI C;  4Y52 K;  1TWC C;  4A3C C;  3S1Q K;  4A3D K;  2PMZ D;  2E2H C;  5C4J K;  4ZH4 A;  4AYB L;  3S15 K;  4A3G K;  1TWF K;  3M4O C;  4OIR A;  1TWH C;  4BY1 C;  2JA8 K;  2YU9 C;  4A3B K;  5IYC K;  3S1M C;  1SFO K;  5TMC A;  3GTO K;  2Y0S L;  4XSX A;  5IP7 C;  3GTL K;  2WB1 D;  2BE5 A;  3S14 C;  1IW7 A;  4LLG A;  4GZY A;  1YNN A;  4Q4Z A;  4A3J C;  3H0G C;  1SFO C;  3I4M K;  2R7Z C;  3HOW C;  3RZD K;  4A3E C;  3S1R K;  3WOD A;  3GTG C;  3S16 C;  3HOY C;  1WCM C;  2NVT C;  3S2H C;  2PPB A;  3GTQ K;  5TMF A;  2VUM C;  5C3E K;  3GTP K;  1SMY A;  1TWA K;  2E2J C;  5IYB C;  3GTK C;  3HOZ C;  4A3F C;  1TWG K;  3FKI K;  3K7A C;  2R92 C;  4KN7 A;  3I4N K;  4A3C K;  2E2H K;  5M3M K;  4NOI A;  4OIO A;  4LK0 A;  4BXX K;  3H3V L;  1I3Q C;  4BY7 C;  4BBS C;  1TWH K;  3S17 C;  4A3L C;  3GTM K;  4Q5S A;  2YU9 K;  3H3V D;  1Y1V C;  5IP9 C;  1R9T C;  4XSZ A;  4LJZ A;  3CQZ K;  3GTJ C;  2WB1 L;  3HOU K;  3S2D C;  1YNJ A;  4OIP A;  4C3J C;  4X6A K;  3S14 K;  5D4D A;  4A3J K;  4MQ9 A;  4A3K C;  4Y7N C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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