4YFXA

Escherichia coli rna polymerase in complex with myxopyronin b
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
229
structure length
229
Chain Sequence
EFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein.
pubmed doi rcsb
source organism Escherichia coli o139:h28 (strain e24377a / etec)
molecule tags Transcription/transcription inhibitor
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 40
structure length 229
sequence length 229
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4yfxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4yfxA01
1SFOC 4BBRK 4A3DC 3EQLA 4OINA 4Y52C 3M3YC 4KMUA 2PMZD 4G7OA 4X6AC 1XPPA 4BBRC 4ZH4A 1I6HK 2NVQC 3RZOK 3GTPC 2Y0SD 3WODA 1TWAK 3FKIC 1K83K 1WCMC 2R93C 3PO3C 4YFNA 3GTOC 3PO2C 1TWGK 4A3KK 2PA8D 2B63K 4C3IC 2NVQK 4A3JC 2CW0A 3S14K 3S1NC 5IP7C 5IYDC 1I50K 3PO2K 3GTGK 1I3QC 4QIWD 3H3VD 2E2JK 4Q5SA 2WB1L 4A3JK 2R7ZK 5M5YK 2E2HC 3S2HK 4YFKA 3HOWC 2PA8L 2BE5A 4QJVB 4G7ZA 3CQZK 3I4NK 3GTGC 1TWFK 3GTJK 4A3LK 4C3HC 2O5JA 3HOZC 4MEYA 2B63C 3RZDK 2YU9K 4C3IK 5IYCC 5FLMC 3GTMK 4BXXC 3S1NK 2WAQD 1R9TC 5C4JK 3HOVK 4A3BK 1BDFA 4QJVA 1Y1VC 3HKZD 3HOYK 4Q4ZA 3M4OC 5C4XK 3K7AC 5IYBC 5IYCK 1TWCC 3GTMC 5FLMK 2R92K 3M3YK 3HOWK 4C3JK 1I6HC 3S17K 4A3IK 1TWFC 4AYBD 4A3LC 4C2MK 4Y7NC 1K83C 4A3KC 3HOVC 1TWGC 3FKIK 2R93K 2NVYC 4A3DK 5C3EC 2JA7C 1TWHK 3S1QK 1YNJA 4A3IC 5IP9C 4C2MC 4BY7C 1R9TK 5C44K 4KN4A 5IP7K 5IYDK 3GTKC 4A3CK 2NVYK 1I6VA 1TWHC 2NVXK 3K7AK 4A93C 5IYBK 1TWCK 4LJZA 4BY7K 4XSZA 2JA5C 5M3FK 2E2HK 3GTOK 3HOXK 2NVTC 3S17C 2VUMC 3GTQK 2NVXC 3GTJC 1SMYA 4QIWL 4Y7NK 3I4MC 2Y0SL 3H3VL 2JA5K 4OIPA 3S16K 4A3MK 4JK1A 4LLGA 4MQ9A 2NVTK 2R7ZC 2O5IA 5C44C 4XLPA 3H0GK 4XLNA 1Y1VK 1Y1WC 3S1RC 4A93K 3S15K 3GTLC 4C3HK 3HOZK 3H0GC 3RZDC 2PPBA 3GTQC 2JA6K 2JA8K 2VUMK 3S2DK 3HKZL 3S1RK 3GTPK 3S15C 4GZYA 3S1MK 4XSXA 4BY1C 1IW7A 3PO3K 4A3MC 4OIOA 2E2IC 5C4XC 2JA8C 2JA6C 5TMCA 3S2DC 4A3GC 3M4OK 3S1MC 4LK0A 4AYBL 1ZYRA 2WAQL 1I50C 1I3QK 2A68A 4YFXA 2E2IK 2A6EA 4KN7A 4A3GK 1TWAC 4A3FC 4BBSC 4LK1A 2A69A 3S2HC 1WCMK 4MEXA 3HOUK 2WB1D 4G7HA 3S1QC 5C3EK 2JA7K 5IP9K 4BY1K 3I4MK 5TMFA 4A3CC 3GTKK 3S16C 4NOIA 2E2JC 4A3EC 5FJ8K 4Y52K 5M5WK 2A6HA 4X6AK 5C4JC 4A3BC 3CQZC 3HOXC 1HQMA 3I4NC 3HOYC 1YNNA 5M3MK 4OIRA 3RZOC 4A3EK 1Y1WK 2R92C 1SFOK 4A3FK 3GTLK 4BBSK 4YG2A 3DXJA 4C3JC 2PMZL 3HOUC 5M5XK 2YU9C 4OIQA 5D4DA 4BXXK 3S14C
chains in the Genus database with same CATH superfamily
1JOEA 3EQLA 3GTPA 4BBRC 2FQOA 3AD8C 3A8JA 4YFNA 3GTOC 3PO2C 1X31C 4C3IC 4A3JC 3S14K 5IP7C 1PJ7A 4XCHA 1I3QC 4QIWD 2GSNA 4PAAA 3S2HK 4QJVB 3I4NK 1K83A 4KAWX 3GTJK 4A3LK 3Q3QA 1O26A 2L3UA 4C3HC 4C3IK 1I3QA 3TFJA 2R93A 3FKIA 1ZQ1C 3GTMK 2GSOA 3TTGA 1BDFA 2RH6A 4Q4ZA 5IYBC 1TWCC 4C3JK 3SZYA 4KATA 1BS2A 4C2MK 4A3LC 3TFIA 3FKIK 2NVYC 2VUMA 5C3EC 2JA7C 1ZXOA 2R92A 2JA5A 4P9SA 1TWHC 2NVXK 3K7AK 4LJZA 3GEIA 3T02A 3HOXK 3GTQK 3GTJC 3H3VL 3GTMA 1BJTA 4LOWA 1XZPB 5IORA 3GTJA 1F9NA 4GTBA 5E68A 5C44C 4XLPA 2P5MA 2PHCB 3HOZK 3RZDC 3LPXA 3GEHA 4KARA 2VUMK 3VA7A 4KMDA 4LQYA 3PIPS 3PO3K 3H0GA 4GTDA 2JA8C 3FHZA 3T00A 1ZYRA 1I3QK 3GTOA 4O2DA 4BKWA 4A3GK 5HL7S 1TWAC 3S2HC 1F7VA 3S1QC 2RGRA 1XZPA 3TFHA 5IP9K 2W7VA 5TMFA 2E2JC 4KB2A 4IOCS 4IOAS 3ADAC 5EGEA 4X6AK 2KPUA 4KMAA 1YNNA 5M3MK 5JVHS 3DLLS 3CF5S 3RZOC 1RU0A 4A3EK 4A3FK 2GAGC 4C3JC 3AQPA 4OIQA 3NUHA 3GTQA 3IPJA 4OINA 4WCES 4KMUA 4G7OA 1XPPA 1USOA 3GTPC 3WODA 1TWAK 1K83K 3HOVK 5DM7S 1B4AA 3L4KA 2PA8D 2B63K 2NVQK 2V6UA 1F93A 1WQGA 2XCRB 4WFBS 5IYDC 3PO2K 1ISEA 3BP8C 4A3JK 2R7ZK 3SZZA 2BE5A 5HL8A 2NVYA 1EH1A 1O2BA 1WOSA 3BUEA 2O5JA 3HOZC 1J6XA 2KWAA 3S1NK 2WAQD 4BLBA 5L46A 1Y1VC 3M4OC 1DCHA 3GTMC 3M3YK 3LAJA 3HOWK 2NVXA 1J6VA 5TJ3A 1I6HC 3S17K 4FM9A 1IS1A 1K83C 3HOVC 4GTLA 4A3DK 3S1QK 1BGWA 1TWHK 4P5BA 4P5AA 1YNJA 4A3IC 5IP9C 4C2MC 4BY7C 5DM6S 5IYDK 2JA7A 2NVYK 1I6VA 4A93C 3GTOK 1O25A 4AH6A 2ZUFA 4G0WA 4Y7NK 2R7ZA 1O27A 2Y0SL 1PJ5A 2JA5K 2XCQA 2Y3PA 3AH5A 2NVTK 1TWAA 2O5IA 2B63A 1EQRA 4KM8A 3S1RC 4A93K 3S15K 1EI6A 4KDDA 4C3HK 3AQOA 1G51A 3N3YA 4WILA 2JA6K 3S2DK 3HKZL 4OIOA 5C4XC 4A3GC 4WF9S 4LK0A 1AB4A 2WAQL 1I50C 2A6EA 3LYWA 2ZJQS 4LK1A 4BBSC 1VGXA 1IBAA 3HOUK 2WB1D 4G7HA 1DD5A 5C3EK 2JA7K 2L5NA 3GDZA 3MMLB 4A3CC 3GTKK 4NOIA 4A3EC 5FJ8K 2FQTA 2A6HA 4A3BC 3I4NC 4OIRA 2R92C 1SFOK 4BBSK 3GTLK 3HOUC 5M5XK 5EGHA 3S14C 3OEPA 4A3DC 3L4JA 2PMZD 4KC6A 4DDQA 4ZH4A 2NVQC 4RMFA 2Y0SD 4C45A 3FKIC 3PO3C 5IOQA 2CW0A 3GTGK 4GTAA 5M5YK 2E2HC 1SFOA 4YFKA 4G0VA 3S0XA 1WSRA 4G7ZA 1VH2A 3G4CA 1VRQC 5IOTA 3HXAA 1XXCA 3AD7C 2KXYA 4PABA 4WJ3M 3HOYK 1INNA 5C4XK 3K7AC 5IYCK 1R9TA 5FLMK 2GAHC 1VJEA 1WQHA 5JVGS 3QX3A 4A3IK 2V6SA 1WOOA 1I50A 3JSTA 4M1XA 5C44K 5IP7K 3GTKC 4A3CK 1WIHA 5IYBK 1TWCK 1JVIA 4BY7K 4XSZA 2JA5C 1TWFA 5M3FK 2E2HK 4WJ4A 2NVTC 2VUMC 4KB4A 1SMYA 2ZJRS 3FOEA 4A3MK 4JK1A 4MQ9A 1Y1WA 2D6FC 1ZVUA 1B4BA 2R7ZC 5CHPA 1TWCA 1Y1WC 4LR2A 3GTGA 3H0GC 2PPBA 3GTQC 5IOSA 3S1RK 3S15C 3GSIA 4XSXA 3FOFA 4BY1C 1IW7A 4A3MC 4GTEA 2E2IC 2GSUA 2JA6C 3S2DC 5TMCA 3M4OK 3GTKA 3S1MC 4AYBL 2A68A 4YFXA 1L0WA 4KN7A 4A3FC 1WCMK 2A69A 1YCLA 5JVOA 2EBBA 4BY1K 1O29A 1UV7A 1DCOA 3OPFA 4Y52K 4GTFA 1TWHA 4KMHA 3CQZC 2E2IA 1HQMA 1O2AA 2YU9A 3HOYC 1Y1WK 1EFWA 1FEUA 1IL2A 5JFEA 4YG2A 2PMZL 2YU9C 4BXXK 3BP3A 2ZFZA 1SFOC 4BBRK 2E2HA 4G0UA 1XZQB 1USMA 1HI9A 4Y52C 3M3YC 4X6AC 1WOPA 3GTLA 4ILDA 1I6HK 4BLAA 3AD9C 3RZOK 4A3KK 1WCMC 2R93C 1TWGK 1XXBA 3S1NC 1WORA 1WQFA 2JA6A 4KM9A 1J98A 1I50K 3N0BA 3H3VD 2E2JK 4Q5SA 1IE0A 4U67S 2WB1L 1IQ0A 3HOWC 2PA8L 4GT9A 3CQZK 3GTGC 1TWGA 1YX2A 1TWFK 4MEYA 2B63C 3RZDK 2YU9K 1C0AA 5IYCC 5FLMC 1O28A 4BXXC 1R9TC 2V6TA 5C4JK 1F7UA 4A3BK 4QJVA 3HKZD 2R92K 2P8TA 1O24A 1TWFC 4AYBD 3N0CA 4Y7NC 4A3KC 1TWGC 2R93K 3G4AA 1WSVA 3A8KA 1R9TK 4KN4A 1JQWA 3CQZA 1J6WA 4WFNS 3S17C 3GIRA 1WCMA 2NVXC 4QIWL 3I4MC 1PJ6A 4OIPA 3S16K 4LLGA 1DCPA 4KASA 1VLOA 3H0GK 4XLNA 2ZUEA 5HQHA 1Y1VK 3GTLC 3GEEA 2CFAA 3V4GA 2JA8K 3GTPK 4GZYA 1XXAA 2XCOA 1ZBSA 3S1MK 2KQ1A 1V5VA 3CAGA 5CJ9A 2CFAB 3OREA 3A8IA 1XZQA 2E2IK 1KQ4A 4MEXA 4IO9S 4WFAS 1EK8A 2ZJPS 3I4MK 3S16C 1Y1VA 3PIOS 4GTCA 5M5WK 3LAPA 5C4JC 3HOXC 4J3NA 4GFQA 1O2FB 4FZBA 3DXJA 3T01A 2JH3A 5D4DA 1GE9A 3ERED
chains in the Genus database with same CATH topology
1SFOC 4BBRK 4A3DC 3EQLA 4OINA 4Y52C 3M3YC 4KMUA 2PMZD 4G7OA 4X6AC 1XPPA 4BBRC 4ZH4A 1I6HK 2NVQC 3RZOK 3GTPC 2Y0SD 3WODA 1TWAK 3FKIC 1K83K 1WCMC 2R93C 3PO3C 4YFNA 3GTOC 3PO2C 1TWGK 4A3KK 2PA8D 2B63K 4C3IC 2NVQK 4A3JC 2CW0A 3S14K 3S1NC 5IP7C 5IYDC 1I50K 3PO2K 3GTGK 1I3QC 4QIWD 3H3VD 2E2JK 4Q5SA 2WB1L 4A3JK 2R7ZK 5M5YK 2E2HC 3S2HK 4YFKA 3HOWC 2PA8L 2BE5A 4QJVB 4G7ZA 3CQZK 3I4NK 3GTGC 1TWFK 3GTJK 4A3LK 4C3HC 2O5JA 3HOZC 4MEYA 2B63C 3RZDK 2YU9K 4C3IK 5IYCC 5FLMC 3GTMK 4BXXC 3S1NK 2WAQD 1R9TC 5C4JK 3HOVK 4A3BK 1BDFA 4QJVA 1Y1VC 3HKZD 3HOYK 4Q4ZA 3M4OC 5C4XK 3K7AC 5IYBC 5IYCK 1TWCC 3GTMC 5FLMK 2R92K 3M3YK 3HOWK 4C3JK 1I6HC 3S17K 4A3IK 1TWFC 4AYBD 4A3LC 4C2MK 4Y7NC 1K83C 4A3KC 3HOVC 1TWGC 3FKIK 2R93K 2NVYC 4A3DK 5C3EC 2JA7C 1TWHK 3S1QK 1YNJA 4A3IC 5IP9C 4C2MC 4BY7C 1R9TK 5C44K 4KN4A 5IP7K 5IYDK 3GTKC 4A3CK 2NVYK 1I6VA 1TWHC 2NVXK 3K7AK 4A93C 5IYBK 1TWCK 4LJZA 4BY7K 4XSZA 2JA5C 5M3FK 2E2HK 3GTOK 3HOXK 2NVTC 3S17C 2VUMC 3GTQK 2NVXC 3GTJC 1SMYA 4QIWL 4Y7NK 3I4MC 2Y0SL 3H3VL 2JA5K 4OIPA 3S16K 4A3MK 4JK1A 4LLGA 4MQ9A 2NVTK 2R7ZC 2O5IA 5C44C 4XLPA 3H0GK 4XLNA 1Y1VK 1Y1WC 3S1RC 4A93K 3S15K 3GTLC 4C3HK 3HOZK 3H0GC 3RZDC 2PPBA 3GTQC 2JA6K 2JA8K 2VUMK 3S2DK 3HKZL 3S1RK 3GTPK 3S15C 4GZYA 3S1MK 4XSXA 4BY1C 1IW7A 3PO3K 4A3MC 4OIOA 2E2IC 5C4XC 2JA8C 2JA6C 5TMCA 3S2DC 4A3GC 3M4OK 3S1MC 4LK0A 4AYBL 1ZYRA 2WAQL 1I50C 1I3QK 2A68A 4YFXA 2E2IK 2A6EA 4KN7A 4A3GK 1TWAC 4A3FC 4BBSC 4LK1A 2A69A 3S2HC 1WCMK 4MEXA 3HOUK 2WB1D 4G7HA 3S1QC 5C3EK 2JA7K 5IP9K 4BY1K 3I4MK 5TMFA 4A3CC 3GTKK 3S16C 4NOIA 2E2JC 4A3EC 5FJ8K 4Y52K 5M5WK 2A6HA 4X6AK 5C4JC 4A3BC 3CQZC 3HOXC 1HQMA 3I4NC 3HOYC 1YNNA 5M3MK 4OIRA 3RZOC 4A3EK 1Y1WK 2R92C 1SFOK 4A3FK 3GTLK 4BBSK 4YG2A 3DXJA 4C3JC 2PMZL 3HOUC 5M5XK 2YU9C 4OIQA 5D4DA 4BXXK 3S14C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SFO C;  4BBR K;  4A3D C;  3EQL A;  4OIN A;  4Y52 C;  3M3Y C;  4KMU A;  2PMZ D;  4G7O A;  4X6A C;  1XPP A;  4BBR C;  4ZH4 A;  1I6H K;  2NVQ C;  3RZO K;  3GTP C;  2Y0S D;  3WOD A;  1TWA K;  3FKI C;  1K83 K;  1WCM C;  2R93 C;  3PO3 C;  4YFN A;  3GTO C;  3PO2 C;  1TWG K;  4A3K K;  2PA8 D;  2B63 K;  4C3I C;  2NVQ K;  4A3J C;  2CW0 A;  3S14 K;  3S1N C;  5IP7 C;  5IYD C;  1I50 K;  3PO2 K;  3GTG K;  1I3Q C;  4QIW D;  3H3V D;  2E2J K;  4Q5S A;  2WB1 L;  4A3J K;  2R7Z K;  5M5Y K;  2E2H C;  3S2H K;  4YFK A;  3HOW C;  2PA8 L;  2BE5 A;  4QJV B;  4G7Z A;  3CQZ K;  3I4N K;  3GTG C;  1TWF K;  3GTJ K;  4A3L K;  4C3H C;  2O5J A;  3HOZ C;  4MEY A;  2B63 C;  3RZD K;  2YU9 K;  4C3I K;  5IYC C;  5FLM C;  3GTM K;  4BXX C;  3S1N K;  2WAQ D;  1R9T C;  5C4J K;  3HOV K;  4A3B K;  1BDF A;  4QJV A;  1Y1V C;  3HKZ D;  3HOY K;  4Q4Z A;  3M4O C;  5C4X K;  3K7A C;  5IYB C;  5IYC K;  1TWC C;  3GTM C;  5FLM K;  2R92 K;  3M3Y K;  3HOW K;  4C3J K;  1I6H C;  3S17 K;  4A3I K;  1TWF C;  4AYB D;  4A3L C;  4C2M K;  4Y7N C;  1K83 C;  4A3K C;  3HOV C;  1TWG C;  3FKI K;  2R93 K;  2NVY C;  4A3D K;  5C3E C;  2JA7 C;  1TWH K;  3S1Q K;  1YNJ A;  4A3I C;  5IP9 C;  4C2M C;  4BY7 C;  1R9T K;  5C44 K;  4KN4 A;  5IP7 K;  5IYD K;  3GTK C;  4A3C K;  2NVY K;  1I6V A;  1TWH C;  2NVX K;  3K7A K;  4A93 C;  5IYB K;  1TWC K;  4LJZ A;  4BY7 K;  4XSZ A;  2JA5 C;  5M3F K;  2E2H K;  3GTO K;  3HOX K;  2NVT C;  3S17 C;  2VUM C;  3GTQ K;  2NVX C;  3GTJ C;  1SMY A;  4QIW L;  4Y7N K;  3I4M C;  2Y0S L;  3H3V L;  2JA5 K;  4OIP A;  3S16 K;  4A3M K;  4JK1 A;  4LLG A;  4MQ9 A;  2NVT K;  2R7Z C;  2O5I A;  5C44 C;  4XLP A;  3H0G K;  4XLN A;  1Y1V K;  1Y1W C;  3S1R C;  4A93 K;  3S15 K;  3GTL C;  4C3H K;  3HOZ K;  3H0G C;  3RZD C;  2PPB A;  3GTQ C;  2JA6 K;  2JA8 K;  2VUM K;  3S2D K;  3HKZ L;  3S1R K;  3GTP K;  3S15 C;  4GZY A;  3S1M K;  4XSX A;  4BY1 C;  1IW7 A;  3PO3 K;  4A3M C;  4OIO A;  2E2I C;  5C4X C;  2JA8 C;  2JA6 C;  5TMC A;  3S2D C;  4A3G C;  3M4O K;  3S1M C;  4LK0 A;  4AYB L;  1ZYR A;  2WAQ L;  1I50 C;  1I3Q K;  2A68 A;  4YFX A;  2E2I K;  2A6E A;  4KN7 A;  4A3G K;  1TWA C;  4A3F C;  4BBS C;  4LK1 A;  2A69 A;  3S2H C;  1WCM K;  4MEX A;  3HOU K;  2WB1 D;  4G7H A;  3S1Q C;  5C3E K;  2JA7 K;  5IP9 K;  4BY1 K;  3I4M K;  5TMF A;  4A3C C;  3GTK K;  3S16 C;  4NOI A;  2E2J C;  4A3E C;  5FJ8 K;  4Y52 K;  5M5W K;  2A6H A;  4X6A K;  5C4J C;  4A3B C;  3CQZ C;  3HOX C;  1HQM A;  3I4N C;  3HOY C;  1YNN A;  5M3M K;  4OIR A;  3RZO C;  4A3E K;  1Y1W K;  2R92 C;  1SFO K;  4A3F K;  3GTL K;  4BBS K;  4YG2 A;  3DXJ A;  4C3J C;  2PMZ L;  3HOU C;  5M5X K;  2YU9 C;  4OIQ A;  5D4D A;  4BXX K;  3S14 C; 
#chains in the Genus database with same CATH topology
 1JOE A;  3EQL A;  3GTP A;  4BBR C;  2FQO A;  3AD8 C;  3A8J A;  4YFN A;  3GTO C;  3PO2 C;  1X31 C;  4C3I C;  4A3J C;  3S14 K;  5IP7 C;  1PJ7 A;  4XCH A;  1I3Q C;  4QIW D;  2GSN A;  4PAA A;  3S2H K;  4QJV B;  3I4N K;  1K83 A;  4KAW X;  3GTJ K;  4A3L K;  3Q3Q A;  1O26 A;  2L3U A;  4C3H C;  4C3I K;  1I3Q A;  3TFJ A;  2R93 A;  3FKI A;  1ZQ1 C;  3GTM K;  2GSO A;  3TTG A;  1BDF A;  2RH6 A;  4Q4Z A;  5IYB C;  1TWC C;  4C3J K;  3SZY A;  4KAT A;  1BS2 A;  4C2M K;  4A3L C;  3TFI A;  3FKI K;  2NVY C;  2VUM A;  5C3E C;  2JA7 C;  1ZXO A;  2R92 A;  2JA5 A;  4P9S A;  1TWH C;  2NVX K;  3K7A K;  4LJZ A;  3GEI A;  3T02 A;  3HOX K;  3GTQ K;  3GTJ C;  3H3V L;  3GTM A;  1BJT A;  4LOW A;  1XZP B;  5IOR A;  3GTJ A;  1F9N A;  4GTB A;  5E68 A;  5C44 C;  4XLP A;  2P5M A;  2PHC B;  3HOZ K;  3RZD C;  3LPX A;  3GEH A;  4KAR A;  2VUM K;  3VA7 A;  4KMD A;  4LQY A;  3PIP S;  3PO3 K;  3H0G A;  4GTD A;  2JA8 C;  3FHZ A;  3T00 A;  1ZYR A;  1I3Q K;  3GTO A;  4O2D A;  4BKW A;  4A3G K;  5HL7 S;  1TWA C;  3S2H C;  1F7V A;  3S1Q C;  2RGR A;  1XZP A;  3TFH A;  5IP9 K;  2W7V A;  5TMF A;  2E2J C;  4KB2 A;  4IOC S;  4IOA S;  3ADA C;  5EGE A;  4X6A K;  2KPU A;  4KMA A;  1YNN A;  5M3M K;  5JVH S;  3DLL S;  3CF5 S;  3RZO C;  1RU0 A;  4A3E K;  4A3F K;  2GAG C;  4C3J C;  3AQP A;  4OIQ A;  3NUH A;  3GTQ A;  3IPJ A;  4OIN A;  4WCE S;  4KMU A;  4G7O A;  1XPP A;  1USO A;  3GTP C;  3WOD A;  1TWA K;  1K83 K;  3HOV K;  5DM7 S;  1B4A A;  3L4K A;  2PA8 D;  2B63 K;  2NVQ K;  2V6U A;  1F93 A;  1WQG A;  2XCR B;  4WFB S;  5IYD C;  3PO2 K;  1ISE A;  3BP8 C;  4A3J K;  2R7Z K;  3SZZ A;  2BE5 A;  5HL8 A;  2NVY A;  1EH1 A;  1O2B A;  1WOS A;  3BUE A;  2O5J A;  3HOZ C;  1J6X A;  2KWA A;  3S1N K;  2WAQ D;  4BLB A;  5L46 A;  1Y1V C;  3M4O C;  1DCH A;  3GTM C;  3M3Y K;  3LAJ A;  3HOW K;  2NVX A;  1J6V A;  5TJ3 A;  1I6H C;  3S17 K;  4FM9 A;  1IS1 A;  1K83 C;  3HOV C;  4GTL A;  4A3D K;  3S1Q K;  1BGW A;  1TWH K;  4P5B A;  4P5A A;  1YNJ A;  4A3I C;  5IP9 C;  4C2M C;  4BY7 C;  5DM6 S;  5IYD K;  2JA7 A;  2NVY K;  1I6V A;  4A93 C;  3GTO K;  1O25 A;  4AH6 A;  2ZUF A;  4G0W A;  4Y7N K;  2R7Z A;  1O27 A;  2Y0S L;  1PJ5 A;  2JA5 K;  2XCQ A;  2Y3P A;  3AH5 A;  2NVT K;  1TWA A;  2O5I A;  2B63 A;  1EQR A;  4KM8 A;  3S1R C;  4A93 K;  3S15 K;  1EI6 A;  4KDD A;  4C3H K;  3AQO A;  1G51 A;  3N3Y A;  4WIL A;  2JA6 K;  3S2D K;  3HKZ L;  4OIO A;  5C4X C;  4A3G C;  4WF9 S;  4LK0 A;  1AB4 A;  2WAQ L;  1I50 C;  2A6E A;  3LYW A;  2ZJQ S;  4LK1 A;  4BBS C;  1VGX A;  1IBA A;  3HOU K;  2WB1 D;  4G7H A;  1DD5 A;  5C3E K;  2JA7 K;  2L5N A;  3GDZ A;  3MML B;  4A3C C;  3GTK K;  4NOI A;  4A3E C;  5FJ8 K;  2FQT A;  2A6H A;  4A3B C;  3I4N C;  4OIR A;  2R92 C;  1SFO K;  4BBS K;  3GTL K;  3HOU C;  5M5X K;  5EGH A;  3S14 C;  3OEP A;  4A3D C;  3L4J A;  2PMZ D;  4KC6 A;  4DDQ A;  4ZH4 A;  2NVQ C;  4RMF A;  2Y0S D;  4C45 A;  3FKI C;  3PO3 C;  5IOQ A;  2CW0 A;  3GTG K;  4GTA A;  5M5Y K;  2E2H C;  1SFO A;  4YFK A;  4G0V A;  3S0X A;  1WSR A;  4G7Z A;  1VH2 A;  3G4C A;  1VRQ C;  5IOT A;  3HXA A;  1XXC A;  3AD7 C;  2KXY A;  4PAB A;  4WJ3 M;  3HOY K;  1INN A;  5C4X K;  3K7A C;  5IYC K;  1R9T A;  5FLM K;  2GAH C;  1VJE A;  1WQH A;  5JVG S;  3QX3 A;  4A3I K;  2V6S A;  1WOO A;  1I50 A;  3JST A;  4M1X A;  5C44 K;  5IP7 K;  3GTK C;  4A3C K;  1WIH A;  5IYB K;  1TWC K;  1JVI A;  4BY7 K;  4XSZ A;  2JA5 C;  1TWF A;  5M3F K;  2E2H K;  4WJ4 A;  2NVT C;  2VUM C;  4KB4 A;  1SMY A;  2ZJR S;  3FOE A;  4A3M K;  4JK1 A;  4MQ9 A;  1Y1W A;  2D6F C;  1ZVU A;  1B4B A;  2R7Z C;  5CHP A;  1TWC A;  1Y1W C;  4LR2 A;  3GTG A;  3H0G C;  2PPB A;  3GTQ C;  5IOS A;  3S1R K;  3S15 C;  3GSI A;  4XSX A;  3FOF A;  4BY1 C;  1IW7 A;  4A3M C;  4GTE A;  2E2I C;  2GSU A;  2JA6 C;  3S2D C;  5TMC A;  3M4O K;  3GTK A;  3S1M C;  4AYB L;  2A68 A;  4YFX A;  1L0W A;  4KN7 A;  4A3F C;  1WCM K;  2A69 A;  1YCL A;  5JVO A;  2EBB A;  4BY1 K;  1O29 A;  1UV7 A;  1DCO A;  3OPF A;  4Y52 K;  4GTF A;  1TWH A;  4KMH A;  3CQZ C;  2E2I A;  1HQM A;  1O2A A;  2YU9 A;  3HOY C;  1Y1W K;  1EFW A;  1FEU A;  1IL2 A;  5JFE A;  4YG2 A;  2PMZ L;  2YU9 C;  4BXX K;  3BP3 A;  2ZFZ A;  1SFO C;  4BBR K;  2E2H A;  4G0U A;  1XZQ B;  1USM A;  1HI9 A;  4Y52 C;  3M3Y C;  4X6A C;  1WOP A;  3GTL A;  4ILD A;  1I6H K;  4BLA A;  3AD9 C;  3RZO K;  4A3K K;  1WCM C;  2R93 C;  1TWG K;  1XXB A;  3S1N C;  1WOR A;  1WQF A;  2JA6 A;  4KM9 A;  1J98 A;  1I50 K;  3N0B A;  3H3V D;  2E2J K;  4Q5S A;  1IE0 A;  4U67 S;  2WB1 L;  1IQ0 A;  3HOW C;  2PA8 L;  4GT9 A;  3CQZ K;  3GTG C;  1TWG A;  1YX2 A;  1TWF K;  4MEY A;  2B63 C;  3RZD K;  2YU9 K;  1C0A A;  5IYC C;  5FLM C;  1O28 A;  4BXX C;  1R9T C;  2V6T A;  5C4J K;  1F7U A;  4A3B K;  4QJV A;  3HKZ D;  2R92 K;  2P8T A;  1O24 A;  1TWF C;  4AYB D;  3N0C A;  4Y7N C;  4A3K C;  1TWG C;  2R93 K;  3G4A A;  1WSV A;  3A8K A;  1R9T K;  4KN4 A;  1JQW A;  3CQZ A;  1J6W A;  4WFN S;  3S17 C;  3GIR A;  1WCM A;  2NVX C;  4QIW L;  3I4M C;  1PJ6 A;  4OIP A;  3S16 K;  4LLG A;  1DCP A;  4KAS A;  1VLO A;  3H0G K;  4XLN A;  2ZUE A;  5HQH A;  1Y1V K;  3GTL C;  3GEE A;  2CFA A;  3V4G A;  2JA8 K;  3GTP K;  4GZY A;  1XXA A;  2XCO A;  1ZBS A;  3S1M K;  2KQ1 A;  1V5V A;  3CAG A;  5CJ9 A;  2CFA B;  3ORE A;  3A8I A;  1XZQ A;  2E2I K;  1KQ4 A;  4MEX A;  4IO9 S;  4WFA S;  1EK8 A;  2ZJP S;  3I4M K;  3S16 C;  1Y1V A;  3PIO S;  4GTC A;  5M5W K;  3LAP A;  5C4J C;  3HOX C;  4J3N A;  4GFQ A;  1O2F B;  4FZB A;  3DXJ A;  3T01 A;  2JH3 A;  5D4D A;  1GE9 A;  3ERE D; 
#chains in the Genus database with same CATH homology
 1SFO C;  4BBR K;  4A3D C;  3EQL A;  4OIN A;  4Y52 C;  3M3Y C;  4KMU A;  2PMZ D;  4G7O A;  4X6A C;  1XPP A;  4BBR C;  4ZH4 A;  1I6H K;  2NVQ C;  3RZO K;  3GTP C;  2Y0S D;  3WOD A;  1TWA K;  3FKI C;  1K83 K;  1WCM C;  2R93 C;  3PO3 C;  4YFN A;  3GTO C;  3PO2 C;  1TWG K;  4A3K K;  2PA8 D;  2B63 K;  4C3I C;  2NVQ K;  4A3J C;  2CW0 A;  3S14 K;  3S1N C;  5IP7 C;  5IYD C;  1I50 K;  3PO2 K;  3GTG K;  1I3Q C;  4QIW D;  3H3V D;  2E2J K;  4Q5S A;  2WB1 L;  4A3J K;  2R7Z K;  5M5Y K;  2E2H C;  3S2H K;  4YFK A;  3HOW C;  2PA8 L;  2BE5 A;  4QJV B;  4G7Z A;  3CQZ K;  3I4N K;  3GTG C;  1TWF K;  3GTJ K;  4A3L K;  4C3H C;  2O5J A;  3HOZ C;  4MEY A;  2B63 C;  3RZD K;  2YU9 K;  4C3I K;  5IYC C;  5FLM C;  3GTM K;  4BXX C;  3S1N K;  2WAQ D;  1R9T C;  5C4J K;  3HOV K;  4A3B K;  1BDF A;  4QJV A;  1Y1V C;  3HKZ D;  3HOY K;  4Q4Z A;  3M4O C;  5C4X K;  3K7A C;  5IYB C;  5IYC K;  1TWC C;  3GTM C;  5FLM K;  2R92 K;  3M3Y K;  3HOW K;  4C3J K;  1I6H C;  3S17 K;  4A3I K;  1TWF C;  4AYB D;  4A3L C;  4C2M K;  4Y7N C;  1K83 C;  4A3K C;  3HOV C;  1TWG C;  3FKI K;  2R93 K;  2NVY C;  4A3D K;  5C3E C;  2JA7 C;  1TWH K;  3S1Q K;  1YNJ A;  4A3I C;  5IP9 C;  4C2M C;  4BY7 C;  1R9T K;  5C44 K;  4KN4 A;  5IP7 K;  5IYD K;  3GTK C;  4A3C K;  2NVY K;  1I6V A;  1TWH C;  2NVX K;  3K7A K;  4A93 C;  5IYB K;  1TWC K;  4LJZ A;  4BY7 K;  4XSZ A;  2JA5 C;  5M3F K;  2E2H K;  3GTO K;  3HOX K;  2NVT C;  3S17 C;  2VUM C;  3GTQ K;  2NVX C;  3GTJ C;  1SMY A;  4QIW L;  4Y7N K;  3I4M C;  2Y0S L;  3H3V L;  2JA5 K;  4OIP A;  3S16 K;  4A3M K;  4JK1 A;  4LLG A;  4MQ9 A;  2NVT K;  2R7Z C;  2O5I A;  5C44 C;  4XLP A;  3H0G K;  4XLN A;  1Y1V K;  1Y1W C;  3S1R C;  4A93 K;  3S15 K;  3GTL C;  4C3H K;  3HOZ K;  3H0G C;  3RZD C;  2PPB A;  3GTQ C;  2JA6 K;  2JA8 K;  2VUM K;  3S2D K;  3HKZ L;  3S1R K;  3GTP K;  3S15 C;  4GZY A;  3S1M K;  4XSX A;  4BY1 C;  1IW7 A;  3PO3 K;  4A3M C;  4OIO A;  2E2I C;  5C4X C;  2JA8 C;  2JA6 C;  5TMC A;  3S2D C;  4A3G C;  3M4O K;  3S1M C;  4LK0 A;  4AYB L;  1ZYR A;  2WAQ L;  1I50 C;  1I3Q K;  2A68 A;  4YFX A;  2E2I K;  2A6E A;  4KN7 A;  4A3G K;  1TWA C;  4A3F C;  4BBS C;  4LK1 A;  2A69 A;  3S2H C;  1WCM K;  4MEX A;  3HOU K;  2WB1 D;  4G7H A;  3S1Q C;  5C3E K;  2JA7 K;  5IP9 K;  4BY1 K;  3I4M K;  5TMF A;  4A3C C;  3GTK K;  3S16 C;  4NOI A;  2E2J C;  4A3E C;  5FJ8 K;  4Y52 K;  5M5W K;  2A6H A;  4X6A K;  5C4J C;  4A3B C;  3CQZ C;  3HOX C;  1HQM A;  3I4N C;  3HOY C;  1YNN A;  5M3M K;  4OIR A;  3RZO C;  4A3E K;  1Y1W K;  2R92 C;  1SFO K;  4A3F K;  3GTL K;  4BBS K;  4YG2 A;  3DXJ A;  4C3J C;  2PMZ L;  3HOU C;  5M5X K;  2YU9 C;  4OIQ A;  5D4D A;  4BXX K;  3S14 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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