4YFXA

Escherichia coli rna polymerase in complex with myxopyronin b
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
229
structure length
229
Chain Sequence
EFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription/transcription inhibitor
molecule keywords DNA-directed RNA polymerase subunit alpha
publication title X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein.
pubmed doi rcsb
source organism Escherichia coli o139:h28 (strain e24377a / etec)
total genus 40
structure length 229
sequence length 229
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4yfxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4yfxA01
4X6AK 4A3CK 2JA8C 4C3IC 3GTOC 3PO3C 1TWFK 3S16K 4YG2A 4C2MC 4A3KK 3RZOK 3GTLC 3FKIC 1BDFA 3GTJK 4Q5SA 2JA6C 1I50K 2R92K 1Y1WK 2JA6K 5D4DA 4LJZA 1TWHK 2Y0SD 4A3LK 4A3MC 2WB1L 5C4JC 5IYBK 5M3FK 3GTPK 5FLMK 3PO2C 4BY7K 3HOWC 3HOVC 3S17C 4Q4ZA 3HKZL 2R7ZK 3S1QK 3S1MK 4A3DK 4KN7A 4QIWD 3S14C 3GTKK 3S14K 4AYBL 2E2IC 2R93C 3HOZK 2VUMK 2CW0A 2A68A 4LLGA 4A3IC 3S1NK 1I6HC 4C3JC 2B63C 3GTQK 3WODA 1TWCC 4C3JK 3S1RK 4OIQA 4X6AC 4A3CC 2NVQK 1ZYRA 1TWFC 1WCMC 3S16C 1SFOK 4NOIA 1TWAK 3H0GK 4A3KC 3RZOC 1WCMK 5M5YK 2E2HC 3GTJC 4A3FK 1I50C 3I4NC 2E2HK 2R92C 3S2HK 1Y1WC 3HOUC 3I4NK 1SMYA 1TWGK 4LK1A 1TWHC 3HOXK 4A3JK 3HOUK 1HQMA 5M5WK 4Y7NK 4A3LC 4BBSK 5IYBC 2PA8L 5C4XK 2YU9K 3GTPC 5FLMC 4BY7C 2JA7K 3I4MK 5TMFA 4KMUA 3S1QC 2R7ZC 4BXXC 4QJVB 3S1MC 4A3DC 2NVYK 4OIPA 4A3EK 4BXXK 3GTKC 1K83K 3S15K 1IW7A 2PMZL 3HOZC 2VUMC 2WAQL 3CQZK 3S1NC 3GTQC 3HOYK 4MQ9A 3H3VD 4YFXA 2A69A 3S1RC 3GTMK 4ZH4A 2NVQC 4C3HK 5C3EK 1SFOC 3M4OK 2PPBA 1TWAC 3H0GC 5IYCK 4G7HA 2E2JK 4A3FC 4JK1A 3S2HC 4XSZA 1R9TK 1Y1VC 4MEXA 1I3QK 5TMCA 1TWGC 1Y1VK 4A3JC 3HOXC 4A3GK 2WB1D 4Y7NC 4A93K 4BBSC 5C4XC 2JA7C 2Y0SL 2YU9C 3I4MC 4BBRK 3RZDK 3HKZD 4KN4A 3HOYC 4A3EC 2JA5C 2NVYC 3K7AK 5IYDK 2JA5K 4Y52K 1K83C 3S15C 4QIWL 3DXJA 4YFNA 1I6VA 5C44K 4BY1K 2NVXK 3S2DK 3CQZC 4XLPA 4QJVA 4GZYA 3GTGK 5IP9C 3M3YK 5M5XK 1YNNA 5IP9K 3PO3K 3GTMC 4C3HC 5C3EC 3M4OC 1YNJA 4C3IK 5M3MK 4XSXA 1XPPA 2JA8K 3GTOK 5IYCC 4C2MK 2E2JC 2NVTC 4XLNA 4OINA 3FKIK 3GTLK 5IP7C 2NVTK 1R9TC 4G7ZA 2O5IA 1I3QC 5IP7K 4A3GC 2O5JA 4OIRA 4OIOA 2PA8D 4A93C 4BBRC 5FJ8K 3RZDC 4A3MK 5C4JK 3PO2K 3HOWK 3HOVK 3S17K 4MEYA 4YFKA 3K7AC 5IYDC 2A6HA 4Y52C 2BE5A 3EQLA 2PMZD 4AYBD 5C44C 4BY1C 2WAQD 2NVXC 4A3BC 3S2DC 4G7OA 2E2IK 4A3IK 2R93K 4LK0A 4A3BK 2A6EA 3GTGC 3M3YC 1I6HK 2B63K 1TWCK 3H3VL
chains in the Genus database with same CATH superfamily
4X6AK 2V6UA 2B63A 3GDZA 3PO3C 3GTLC 1WCMA 4Q5SA 2KXYA 1IL2A 1B4AA 1O25A 1TWGA 4A3MC 5C4JC 4WJ4A 1TWHA 3HOWC 3OEPA 3S1QK 3TFHA 2R7ZK 1EQRA 3GSIA 3AQOA 2E2IC 3GTKA 4A3IC 3S1NK 4KMAA 4C3JK 4KM9A 4OIQA 4X6AC 3GTQA 1USMA 4PABA 2NVQK 1SFOK 1TWAK 2Y3PA 5M5YK 1JOEA 3GEHA 3I4NK 3LAJA 4LK1A 4Y7NK 4G0UA 5C4XK 4BBSK 3L4KA 4KMUA 3S1QC 2R7ZC 4BXXC 4QJVB 1EFWA 5JVOA 3T00A 4IOAS 2JA5A 1DCOA 3FOFA 3S1NC 4KASA 4ILDA 4MQ9A 2RGRA 4YFXA 2A69A 1EK8A 3PIPS 4ZH4A 2NVQC 4C3HK 5C3EK 1SFOC 1TWAC 5IYCK 3GTMA 1INNA 4KATA 1Y1VC 1I3QK 3AH5A 1R9TA 4Y7NC 2PHCB 5IOSA 4BBSC 5C4XC 3S0XA 4KN4A 3SZYA 3K7AK 3AQPA 1PJ7A 1L0WA 3ERED 4XLPA 4U67S 4WJ3M 1XZPA 5IP9C 4GTCA 1VGXA 3FOEA 4KDDA 4C3HC 5C3EC 5M3MK 4C3IK 1FEUA 2ZJPS 2FQOA 5IYCC 2NVTC 2GAHC 1O29A 1I3QC 2R92A 1EI6A 2O5JA 2JA6A 2PA8D 5FJ8K 3PO2K 3A8JA 3HOVK 4PAAA 4MEYA 3CAGA 3K7AC 2BE5A 2KWAA 1VH2A 4GTAA 4GTLA 4BLAA 2R93K 1UV7A 2B63K 3TTGA 1USOA 1XXCA 4C3IC 1TWFK 4AH6A 3H0GA 2E2HA 3GTJA 5D4DA 4LJZA 1I50A 1TWHK 1BGWA 4A3LK 5IYBK 2EBBA 3PO2C 3HOVC 5EGEA 3S1MK 4A3DK 3GTKK 1WOPA 2R93C 2CW0A 3OPFA 3GTQK 2VUMA 2B63C 2D6FC 4LR2A 3MMLB 1ZYRA 1TWFC 1WCMC 1O27A 1SMYA 3TFJA 5IORA 4WILA 1TWHC 3HOXK 1HQMA 4A3LC 5IYBC 2PA8L 2FQTA 5TMFA 1IE0A 4J3NA 2JA7A 4GTEA 3S1MC 4A3DC 4A3EK 2YU9A 4BXXK 3GTKC 1IW7A 5IOQA 1F7UA 3AD9C 3GTQC 4WFBS 5IOTA 3M4OK 1KQ4A 3HXAA 1WSVA 1O2AA 1R9TK 4IO9S 4M1XA 1O2BA 1Y1VK 3HOXC 2WB1D 5JFEA 4A93K 4BBRK 3GIRA 1JQWA 4A3EC 2JA5C 5IYDK 3DXJA 4DDQA 2V6TA 3S2DK 4BY1K 1WORA 5EGHA 2NVXA 4QJVA 3GTGK 3GEEA 1YNNA 5IP9K 1J6VA 3GTMC 2V6SA 3M4OC 1YNJA 3GTOK 1VLOA 4C2MK 4XLNA 4OINA 3FKIK 2NVTK 1R9TC 4G7ZA 4G0VA 1F9NA 4A93C 4BBRC 4C45A 3S17K 4BLBA 4YFKA 1X31C 5IYDC 2R7ZA 2PMZD 4WF9S 1RU0A 3S2DC 4BY1C 2WAQD 4A3BC 4G7OA 3N3YA 3GTGC 1BS2A 1TWCK 3VA7A 5TJ3A 1YX2A 3GTOC 1V5VA 1XZQB 3S16K 4C2MC 3FKIC 1BDFA 5JVGS 3GTJK 1B4BA 2JA6C 1I50K 1ZQ1C 2Y0SD 2RH6A 1Y1WA 2WB1L 1AB4A 5M3FK 4BY7K 1IBAA 3S17C 3GTPA 4KN7A 4QIWD 3S14C 1DCPA 5L46A 4KMHA 4KM8A 4AYBL 2JH3A 2VUMK 4LLGA 2GSUA 1J6WA 1BJTA 1TWCC 3S1RK 3S16C 4NOIA 1WCMK 2E2HC 3GTJC 1PJ5A 1I50C 1O2FB 3HOUC 1TWGK 3Q3QA 5M5WK 5CJ9A 5CHPA 2JA7K 2YU9K 4BY7C 3I4MK 3HOYK 4P5AA 3A8KA 3IPJA 4WFNS 2W7VA 3S15K 2NVYA 4KC6A 2PMZL 1K83A 2VUMC 2WAQL 3T01A 1WIHA 3CQZA 4KMDA 2ZUEA 3S1RC 1WOOA 2ZJQS 2CFAB 2PPBA 4KARA 4BKWA 4G7HA 2E2JK 1XXBA 4JK1A 3OREA 5TMCA 5HL8A 1TWGC 4A3GK 2JA7C 2Y0SL 2YU9C 3I4MC 4LOWA 3SZZA 3HKZD 2XCRB 3HOYC 2JA5K 2P8TA 4QIWL 3S15C 1I6VA 5C44K 2NVXK 4GZYA 3M3YK 5DM7S 3LYWA 1JVIA 3BP8C 2JA8K 3GTMK 1WOSA 1XPPA 1TWFA 2E2JC 5IP7C 2O5IA 3ADAC 4LQYA 3GTLA 4A3GC 4OIRA 4WCES 3GEIA 4GTFA 4P9SA 4KAWX 3EQLA 1IQ0A 4AYBD 5C44C 2NVXC 4KB2A 3BUEA 4A3BK 2A6EA 2E2IA 3M3YC 1I6HK 1EH1A 2L3UA 4A3CK 4G0WA 2JA8C 4YG2A 1O28A 4RMFA 4A3KK 3RZOK 2XCOA 2R92K 1Y1WK 2JA6K 1XXAA 1J98A 2GSOA 3G4AA 5FLMK 3GTPK 1VJEA 3HKZL 4Q4ZA 3S14K 5E68A 3HOZK 2A68A 1F93A 2ZUFA 1I6HC 4C3JC 3WODA 1WQGA 1ZXOA 1WQFA 3AD8C 1J6XA 4A3CC 1DD5A 3H0GK 4A3KC 3RZOC 5HQHA 2ZJRS 4O2DA 4A3FK 1SFOA 1TWAA 3I4NC 3DLLS 2R92C 2E2HK 1Y1WC 3S2HK 3HOUK 4A3JK 2P5MA 1Y1VA 5HL7S 1XZQA 3GTPC 5FLMC 1XZPB 1WSRA 2NVYK 4OIPA 3QX3A 5JVHS 1K83K 3CF5S 1ZBSA 4FM9A 3HOZC 1WQHA 3CQZK 2GAGC 3JSTA 5DM6S 2GSNA 3H3VD 3V4GA 1F7VA 3GTGA 3T02A 3N0BA 4IOCS 4GTDA 1VRQC 3H0GC 1ZVUA 2XCQA 3GTOA 3A8IA 4A3FC 4XCHA 3S2HC 4XSZA 3FKIA 1GE9A 4MEXA 3LPXA 4A3JC 4P5BA 1I3QA 3RZDK 1PJ6A 2NVYC 4Y52K 1K83C 4YFNA 2ZFZA 1O24A 3CQZC 3FHZA 3LAPA 3PIOS 4KB4A 5M5XK 1HI9A 3BP3A 1ISEA 1TWCA 3PO3K 4XSXA 1YCLA 1G51A 3NUHA 3GTLK 1IS1A 3L4JA 2KPUA 5IP7K 1DCHA 2CFAA 4GT9A 4OIOA 3AD7C 3RZDC 4A3MK 1O26A 5C4JK 3HOWK 4WFAS 4FZBA 4GTBA 2A6HA 4Y52C 4GFQA 2E2IK 3N0CA 4A3IK 4LK0A 3TFIA 3G4CA 2KQ1A 2R93A 1C0AA 2L5NA 3H3VL
chains in the Genus database with same CATH topology
4X6AK 4A3CK 2JA8C 4C3IC 3GTOC 3PO3C 1TWFK 3S16K 4YG2A 4C2MC 4A3KK 3RZOK 3GTLC 3FKIC 1BDFA 3GTJK 4Q5SA 2JA6C 1I50K 2R92K 1Y1WK 2JA6K 5D4DA 4LJZA 1TWHK 2Y0SD 4A3LK 4A3MC 2WB1L 5C4JC 5IYBK 5M3FK 3GTPK 5FLMK 3PO2C 4BY7K 3HOWC 3HOVC 3S17C 4Q4ZA 3HKZL 2R7ZK 3S1QK 3S1MK 4A3DK 4KN7A 4QIWD 3S14C 3GTKK 3S14K 4AYBL 2E2IC 2R93C 3HOZK 2VUMK 2CW0A 2A68A 4LLGA 4A3IC 3S1NK 1I6HC 4C3JC 2B63C 3GTQK 3WODA 1TWCC 4C3JK 3S1RK 4OIQA 4X6AC 4A3CC 2NVQK 1ZYRA 1TWFC 1WCMC 3S16C 1SFOK 4NOIA 1TWAK 3H0GK 4A3KC 3RZOC 1WCMK 5M5YK 2E2HC 3GTJC 4A3FK 1I50C 3I4NC 2E2HK 2R92C 3S2HK 1Y1WC 3HOUC 3I4NK 1SMYA 1TWGK 4LK1A 1TWHC 3HOXK 4A3JK 3HOUK 1HQMA 5M5WK 4Y7NK 4A3LC 4BBSK 5IYBC 2PA8L 5C4XK 2YU9K 3GTPC 5FLMC 4BY7C 2JA7K 3I4MK 5TMFA 4KMUA 3S1QC 2R7ZC 4BXXC 4QJVB 3S1MC 4A3DC 2NVYK 4OIPA 4A3EK 4BXXK 3GTKC 1K83K 3S15K 1IW7A 2PMZL 3HOZC 2VUMC 2WAQL 3CQZK 3S1NC 3GTQC 3HOYK 4MQ9A 3H3VD 4YFXA 2A69A 3S1RC 3GTMK 4ZH4A 2NVQC 4C3HK 5C3EK 1SFOC 3M4OK 2PPBA 1TWAC 3H0GC 5IYCK 4G7HA 2E2JK 4A3FC 4JK1A 3S2HC 4XSZA 1R9TK 1Y1VC 4MEXA 1I3QK 5TMCA 1TWGC 1Y1VK 4A3JC 3HOXC 4A3GK 2WB1D 4Y7NC 4A93K 4BBSC 5C4XC 2JA7C 2Y0SL 2YU9C 3I4MC 4BBRK 3RZDK 3HKZD 4KN4A 3HOYC 4A3EC 2JA5C 2NVYC 3K7AK 5IYDK 2JA5K 4Y52K 1K83C 3S15C 4QIWL 3DXJA 4YFNA 1I6VA 5C44K 4BY1K 2NVXK 3S2DK 3CQZC 4XLPA 4QJVA 4GZYA 3GTGK 5IP9C 3M3YK 5M5XK 1YNNA 5IP9K 3PO3K 3GTMC 4C3HC 5C3EC 3M4OC 1YNJA 4C3IK 5M3MK 4XSXA 1XPPA 2JA8K 3GTOK 5IYCC 4C2MK 2E2JC 2NVTC 4XLNA 4OINA 3FKIK 3GTLK 5IP7C 2NVTK 1R9TC 4G7ZA 2O5IA 1I3QC 5IP7K 4A3GC 2O5JA 4OIRA 4OIOA 2PA8D 4A93C 4BBRC 5FJ8K 3RZDC 4A3MK 5C4JK 3PO2K 3HOWK 3HOVK 3S17K 4MEYA 4YFKA 3K7AC 5IYDC 2A6HA 4Y52C 2BE5A 3EQLA 2PMZD 4AYBD 5C44C 4BY1C 2WAQD 2NVXC 4A3BC 3S2DC 4G7OA 2E2IK 4A3IK 2R93K 4LK0A 4A3BK 2A6EA 3GTGC 3M3YC 1I6HK 2B63K 1TWCK 3H3VL
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4X6A K;  4A3C K;  2JA8 C;  4C3I C;  3GTO C;  3PO3 C;  1TWF K;  3S16 K;  4YG2 A;  4C2M C;  4A3K K;  3RZO K;  3GTL C;  3FKI C;  1BDF A;  3GTJ K;  4Q5S A;  2JA6 C;  1I50 K;  2R92 K;  1Y1W K;  2JA6 K;  5D4D A;  4LJZ A;  1TWH K;  2Y0S D;  4A3L K;  4A3M C;  2WB1 L;  5C4J C;  5IYB K;  5M3F K;  3GTP K;  5FLM K;  3PO2 C;  4BY7 K;  3HOW C;  3HOV C;  3S17 C;  4Q4Z A;  3HKZ L;  2R7Z K;  3S1Q K;  3S1M K;  4A3D K;  4KN7 A;  4QIW D;  3S14 C;  3GTK K;  3S14 K;  4AYB L;  2E2I C;  2R93 C;  3HOZ K;  2VUM K;  2CW0 A;  2A68 A;  4LLG A;  4A3I C;  3S1N K;  1I6H C;  4C3J C;  2B63 C;  3GTQ K;  3WOD A;  1TWC C;  4C3J K;  3S1R K;  4OIQ A;  4X6A C;  4A3C C;  2NVQ K;  1ZYR A;  1TWF C;  1WCM C;  3S16 C;  1SFO K;  4NOI A;  1TWA K;  3H0G K;  4A3K C;  3RZO C;  1WCM K;  5M5Y K;  2E2H C;  3GTJ C;  4A3F K;  1I50 C;  3I4N C;  2E2H K;  2R92 C;  3S2H K;  1Y1W C;  3HOU C;  3I4N K;  1SMY A;  1TWG K;  4LK1 A;  1TWH C;  3HOX K;  4A3J K;  3HOU K;  1HQM A;  5M5W K;  4Y7N K;  4A3L C;  4BBS K;  5IYB C;  2PA8 L;  5C4X K;  2YU9 K;  3GTP C;  5FLM C;  4BY7 C;  2JA7 K;  3I4M K;  5TMF A;  4KMU A;  3S1Q C;  2R7Z C;  4BXX C;  4QJV B;  3S1M C;  4A3D C;  2NVY K;  4OIP A;  4A3E K;  4BXX K;  3GTK C;  1K83 K;  3S15 K;  1IW7 A;  2PMZ L;  3HOZ C;  2VUM C;  2WAQ L;  3CQZ K;  3S1N C;  3GTQ C;  3HOY K;  4MQ9 A;  3H3V D;  4YFX A;  2A69 A;  3S1R C;  3GTM K;  4ZH4 A;  2NVQ C;  4C3H K;  5C3E K;  1SFO C;  3M4O K;  2PPB A;  1TWA C;  3H0G C;  5IYC K;  4G7H A;  2E2J K;  4A3F C;  4JK1 A;  3S2H C;  4XSZ A;  1R9T K;  1Y1V C;  4MEX A;  1I3Q K;  5TMC A;  1TWG C;  1Y1V K;  4A3J C;  3HOX C;  4A3G K;  2WB1 D;  4Y7N C;  4A93 K;  4BBS C;  5C4X C;  2JA7 C;  2Y0S L;  2YU9 C;  3I4M C;  4BBR K;  3RZD K;  3HKZ D;  4KN4 A;  3HOY C;  4A3E C;  2JA5 C;  2NVY C;  3K7A K;  5IYD K;  2JA5 K;  4Y52 K;  1K83 C;  3S15 C;  4QIW L;  3DXJ A;  4YFN A;  1I6V A;  5C44 K;  4BY1 K;  2NVX K;  3S2D K;  3CQZ C;  4XLP A;  4QJV A;  4GZY A;  3GTG K;  5IP9 C;  3M3Y K;  5M5X K;  1YNN A;  5IP9 K;  3PO3 K;  3GTM C;  4C3H C;  5C3E C;  3M4O C;  1YNJ A;  4C3I K;  5M3M K;  4XSX A;  1XPP A;  2JA8 K;  3GTO K;  5IYC C;  4C2M K;  2E2J C;  2NVT C;  4XLN A;  4OIN A;  3FKI K;  3GTL K;  5IP7 C;  2NVT K;  1R9T C;  4G7Z A;  2O5I A;  1I3Q C;  5IP7 K;  4A3G C;  2O5J A;  4OIR A;  4OIO A;  2PA8 D;  4A93 C;  4BBR C;  5FJ8 K;  3RZD C;  4A3M K;  5C4J K;  3PO2 K;  3HOW K;  3HOV K;  3S17 K;  4MEY A;  4YFK A;  3K7A C;  5IYD C;  2A6H A;  4Y52 C;  2BE5 A;  3EQL A;  2PMZ D;  4AYB D;  5C44 C;  4BY1 C;  2WAQ D;  2NVX C;  4A3B C;  3S2D C;  4G7O A;  2E2I K;  4A3I K;  2R93 K;  4LK0 A;  4A3B K;  2A6E A;  3GTG C;  3M3Y C;  1I6H K;  2B63 K;  1TWC K;  3H3V L; 
#chains in the Genus database with same CATH topology
 4X6A K;  2V6U A;  2B63 A;  3GDZ A;  3PO3 C;  3GTL C;  1WCM A;  4Q5S A;  2KXY A;  1IL2 A;  1B4A A;  1O25 A;  1TWG A;  4A3M C;  5C4J C;  4WJ4 A;  1TWH A;  3HOW C;  3OEP A;  3S1Q K;  3TFH A;  2R7Z K;  1EQR A;  3GSI A;  3AQO A;  2E2I C;  3GTK A;  4A3I C;  3S1N K;  4KMA A;  4C3J K;  4KM9 A;  4OIQ A;  4X6A C;  3GTQ A;  1USM A;  4PAB A;  2NVQ K;  1SFO K;  1TWA K;  2Y3P A;  5M5Y K;  1JOE A;  3GEH A;  3I4N K;  3LAJ A;  4LK1 A;  4Y7N K;  4G0U A;  5C4X K;  4BBS K;  3L4K A;  4KMU A;  3S1Q C;  2R7Z C;  4BXX C;  4QJV B;  1EFW A;  5JVO A;  3T00 A;  4IOA S;  2JA5 A;  1DCO A;  3FOF A;  3S1N C;  4KAS A;  4ILD A;  4MQ9 A;  2RGR A;  4YFX A;  2A69 A;  1EK8 A;  3PIP S;  4ZH4 A;  2NVQ C;  4C3H K;  5C3E K;  1SFO C;  1TWA C;  5IYC K;  3GTM A;  1INN A;  4KAT A;  1Y1V C;  1I3Q K;  3AH5 A;  1R9T A;  4Y7N C;  2PHC B;  5IOS A;  4BBS C;  5C4X C;  3S0X A;  4KN4 A;  3SZY A;  3K7A K;  3AQP A;  1PJ7 A;  1L0W A;  3ERE D;  4XLP A;  4U67 S;  4WJ3 M;  1XZP A;  5IP9 C;  4GTC A;  1VGX A;  3FOE A;  4KDD A;  4C3H C;  5C3E C;  5M3M K;  4C3I K;  1FEU A;  2ZJP S;  2FQO A;  5IYC C;  2NVT C;  2GAH C;  1O29 A;  1I3Q C;  2R92 A;  1EI6 A;  2O5J A;  2JA6 A;  2PA8 D;  5FJ8 K;  3PO2 K;  3A8J A;  3HOV K;  4PAA A;  4MEY A;  3CAG A;  3K7A C;  2BE5 A;  2KWA A;  1VH2 A;  4GTA A;  4GTL A;  4BLA A;  2R93 K;  1UV7 A;  2B63 K;  3TTG A;  1USO A;  1XXC A;  4C3I C;  1TWF K;  4AH6 A;  3H0G A;  2E2H A;  3GTJ A;  5D4D A;  4LJZ A;  1I50 A;  1TWH K;  1BGW A;  4A3L K;  5IYB K;  2EBB A;  3PO2 C;  3HOV C;  5EGE A;  3S1M K;  4A3D K;  3GTK K;  1WOP A;  2R93 C;  2CW0 A;  3OPF A;  3GTQ K;  2VUM A;  2B63 C;  2D6F C;  4LR2 A;  3MML B;  1ZYR A;  1TWF C;  1WCM C;  1O27 A;  1SMY A;  3TFJ A;  5IOR A;  4WIL A;  1TWH C;  3HOX K;  1HQM A;  4A3L C;  5IYB C;  2PA8 L;  2FQT A;  5TMF A;  1IE0 A;  4J3N A;  2JA7 A;  4GTE A;  3S1M C;  4A3D C;  4A3E K;  2YU9 A;  4BXX K;  3GTK C;  1IW7 A;  5IOQ A;  1F7U A;  3AD9 C;  3GTQ C;  4WFB S;  5IOT A;  3M4O K;  1KQ4 A;  3HXA A;  1WSV A;  1O2A A;  1R9T K;  4IO9 S;  4M1X A;  1O2B A;  1Y1V K;  3HOX C;  2WB1 D;  5JFE A;  4A93 K;  4BBR K;  3GIR A;  1JQW A;  4A3E C;  2JA5 C;  5IYD K;  3DXJ A;  4DDQ A;  2V6T A;  3S2D K;  4BY1 K;  1WOR A;  5EGH A;  2NVX A;  4QJV A;  3GTG K;  3GEE A;  1YNN A;  5IP9 K;  1J6V A;  3GTM C;  2V6S A;  3M4O C;  1YNJ A;  3GTO K;  1VLO A;  4C2M K;  4XLN A;  4OIN A;  3FKI K;  2NVT K;  1R9T C;  4G7Z A;  4G0V A;  1F9N A;  4A93 C;  4BBR C;  4C45 A;  3S17 K;  4BLB A;  4YFK A;  1X31 C;  5IYD C;  2R7Z A;  2PMZ D;  4WF9 S;  1RU0 A;  3S2D C;  4BY1 C;  2WAQ D;  4A3B C;  4G7O A;  3N3Y A;  3GTG C;  1BS2 A;  1TWC K;  3VA7 A;  5TJ3 A;  1YX2 A;  3GTO C;  1V5V A;  1XZQ B;  3S16 K;  4C2M C;  3FKI C;  1BDF A;  5JVG S;  3GTJ K;  1B4B A;  2JA6 C;  1I50 K;  1ZQ1 C;  2Y0S D;  2RH6 A;  1Y1W A;  2WB1 L;  1AB4 A;  5M3F K;  4BY7 K;  1IBA A;  3S17 C;  3GTP A;  4KN7 A;  4QIW D;  3S14 C;  1DCP A;  5L46 A;  4KMH A;  4KM8 A;  4AYB L;  2JH3 A;  2VUM K;  4LLG A;  2GSU A;  1J6W A;  1BJT A;  1TWC C;  3S1R K;  3S16 C;  4NOI A;  1WCM K;  2E2H C;  3GTJ C;  1PJ5 A;  1I50 C;  1O2F B;  3HOU C;  1TWG K;  3Q3Q A;  5M5W K;  5CJ9 A;  5CHP A;  2JA7 K;  2YU9 K;  4BY7 C;  3I4M K;  3HOY K;  4P5A A;  3A8K A;  3IPJ A;  4WFN S;  2W7V A;  3S15 K;  2NVY A;  4KC6 A;  2PMZ L;  1K83 A;  2VUM C;  2WAQ L;  3T01 A;  1WIH A;  3CQZ A;  4KMD A;  2ZUE A;  3S1R C;  1WOO A;  2ZJQ S;  2CFA B;  2PPB A;  4KAR A;  4BKW A;  4G7H A;  2E2J K;  1XXB A;  4JK1 A;  3ORE A;  5TMC A;  5HL8 A;  1TWG C;  4A3G K;  2JA7 C;  2Y0S L;  2YU9 C;  3I4M C;  4LOW A;  3SZZ A;  3HKZ D;  2XCR B;  3HOY C;  2JA5 K;  2P8T A;  4QIW L;  3S15 C;  1I6V A;  5C44 K;  2NVX K;  4GZY A;  3M3Y K;  5DM7 S;  3LYW A;  1JVI A;  3BP8 C;  2JA8 K;  3GTM K;  1WOS A;  1XPP A;  1TWF A;  2E2J C;  5IP7 C;  2O5I A;  3ADA C;  4LQY A;  3GTL A;  4A3G C;  4OIR A;  4WCE S;  3GEI A;  4GTF A;  4P9S A;  4KAW X;  3EQL A;  1IQ0 A;  4AYB D;  5C44 C;  2NVX C;  4KB2 A;  3BUE A;  4A3B K;  2A6E A;  2E2I A;  3M3Y C;  1I6H K;  1EH1 A;  2L3U A;  4A3C K;  4G0W A;  2JA8 C;  4YG2 A;  1O28 A;  4RMF A;  4A3K K;  3RZO K;  2XCO A;  2R92 K;  1Y1W K;  2JA6 K;  1XXA A;  1J98 A;  2GSO A;  3G4A A;  5FLM K;  3GTP K;  1VJE A;  3HKZ L;  4Q4Z A;  3S14 K;  5E68 A;  3HOZ K;  2A68 A;  1F93 A;  2ZUF A;  1I6H C;  4C3J C;  3WOD A;  1WQG A;  1ZXO A;  1WQF A;  3AD8 C;  1J6X A;  4A3C C;  1DD5 A;  3H0G K;  4A3K C;  3RZO C;  5HQH A;  2ZJR S;  4O2D A;  4A3F K;  1SFO A;  1TWA A;  3I4N C;  3DLL S;  2R92 C;  2E2H K;  1Y1W C;  3S2H K;  3HOU K;  4A3J K;  2P5M A;  1Y1V A;  5HL7 S;  1XZQ A;  3GTP C;  5FLM C;  1XZP B;  1WSR A;  2NVY K;  4OIP A;  3QX3 A;  5JVH S;  1K83 K;  3CF5 S;  1ZBS A;  4FM9 A;  3HOZ C;  1WQH A;  3CQZ K;  2GAG C;  3JST A;  5DM6 S;  2GSN A;  3H3V D;  3V4G A;  1F7V A;  3GTG A;  3T02 A;  3N0B A;  4IOC S;  4GTD A;  1VRQ C;  3H0G C;  1ZVU A;  2XCQ A;  3GTO A;  3A8I A;  4A3F C;  4XCH A;  3S2H C;  4XSZ A;  3FKI A;  1GE9 A;  4MEX A;  3LPX A;  4A3J C;  4P5B A;  1I3Q A;  3RZD K;  1PJ6 A;  2NVY C;  4Y52 K;  1K83 C;  4YFN A;  2ZFZ A;  1O24 A;  3CQZ C;  3FHZ A;  3LAP A;  3PIO S;  4KB4 A;  5M5X K;  1HI9 A;  3BP3 A;  1ISE A;  1TWC A;  3PO3 K;  4XSX A;  1YCL A;  1G51 A;  3NUH A;  3GTL K;  1IS1 A;  3L4J A;  2KPU A;  5IP7 K;  1DCH A;  2CFA A;  4GT9 A;  4OIO A;  3AD7 C;  3RZD C;  4A3M K;  1O26 A;  5C4J K;  3HOW K;  4WFA S;  4FZB A;  4GTB A;  2A6H A;  4Y52 C;  4GFQ A;  2E2I K;  3N0C A;  4A3I K;  4LK0 A;  3TFI A;  3G4C A;  2KQ1 A;  2R93 A;  1C0A A;  2L5N A;  3H3V L; 
#chains in the Genus database with same CATH homology
 4X6A K;  4A3C K;  2JA8 C;  4C3I C;  3GTO C;  3PO3 C;  1TWF K;  3S16 K;  4YG2 A;  4C2M C;  4A3K K;  3RZO K;  3GTL C;  3FKI C;  1BDF A;  3GTJ K;  4Q5S A;  2JA6 C;  1I50 K;  2R92 K;  1Y1W K;  2JA6 K;  5D4D A;  4LJZ A;  1TWH K;  2Y0S D;  4A3L K;  4A3M C;  2WB1 L;  5C4J C;  5IYB K;  5M3F K;  3GTP K;  5FLM K;  3PO2 C;  4BY7 K;  3HOW C;  3HOV C;  3S17 C;  4Q4Z A;  3HKZ L;  2R7Z K;  3S1Q K;  3S1M K;  4A3D K;  4KN7 A;  4QIW D;  3S14 C;  3GTK K;  3S14 K;  4AYB L;  2E2I C;  2R93 C;  3HOZ K;  2VUM K;  2CW0 A;  2A68 A;  4LLG A;  4A3I C;  3S1N K;  1I6H C;  4C3J C;  2B63 C;  3GTQ K;  3WOD A;  1TWC C;  4C3J K;  3S1R K;  4OIQ A;  4X6A C;  4A3C C;  2NVQ K;  1ZYR A;  1TWF C;  1WCM C;  3S16 C;  1SFO K;  4NOI A;  1TWA K;  3H0G K;  4A3K C;  3RZO C;  1WCM K;  5M5Y K;  2E2H C;  3GTJ C;  4A3F K;  1I50 C;  3I4N C;  2E2H K;  2R92 C;  3S2H K;  1Y1W C;  3HOU C;  3I4N K;  1SMY A;  1TWG K;  4LK1 A;  1TWH C;  3HOX K;  4A3J K;  3HOU K;  1HQM A;  5M5W K;  4Y7N K;  4A3L C;  4BBS K;  5IYB C;  2PA8 L;  5C4X K;  2YU9 K;  3GTP C;  5FLM C;  4BY7 C;  2JA7 K;  3I4M K;  5TMF A;  4KMU A;  3S1Q C;  2R7Z C;  4BXX C;  4QJV B;  3S1M C;  4A3D C;  2NVY K;  4OIP A;  4A3E K;  4BXX K;  3GTK C;  1K83 K;  3S15 K;  1IW7 A;  2PMZ L;  3HOZ C;  2VUM C;  2WAQ L;  3CQZ K;  3S1N C;  3GTQ C;  3HOY K;  4MQ9 A;  3H3V D;  4YFX A;  2A69 A;  3S1R C;  3GTM K;  4ZH4 A;  2NVQ C;  4C3H K;  5C3E K;  1SFO C;  3M4O K;  2PPB A;  1TWA C;  3H0G C;  5IYC K;  4G7H A;  2E2J K;  4A3F C;  4JK1 A;  3S2H C;  4XSZ A;  1R9T K;  1Y1V C;  4MEX A;  1I3Q K;  5TMC A;  1TWG C;  1Y1V K;  4A3J C;  3HOX C;  4A3G K;  2WB1 D;  4Y7N C;  4A93 K;  4BBS C;  5C4X C;  2JA7 C;  2Y0S L;  2YU9 C;  3I4M C;  4BBR K;  3RZD K;  3HKZ D;  4KN4 A;  3HOY C;  4A3E C;  2JA5 C;  2NVY C;  3K7A K;  5IYD K;  2JA5 K;  4Y52 K;  1K83 C;  3S15 C;  4QIW L;  3DXJ A;  4YFN A;  1I6V A;  5C44 K;  4BY1 K;  2NVX K;  3S2D K;  3CQZ C;  4XLP A;  4QJV A;  4GZY A;  3GTG K;  5IP9 C;  3M3Y K;  5M5X K;  1YNN A;  5IP9 K;  3PO3 K;  3GTM C;  4C3H C;  5C3E C;  3M4O C;  1YNJ A;  4C3I K;  5M3M K;  4XSX A;  1XPP A;  2JA8 K;  3GTO K;  5IYC C;  4C2M K;  2E2J C;  2NVT C;  4XLN A;  4OIN A;  3FKI K;  3GTL K;  5IP7 C;  2NVT K;  1R9T C;  4G7Z A;  2O5I A;  1I3Q C;  5IP7 K;  4A3G C;  2O5J A;  4OIR A;  4OIO A;  2PA8 D;  4A93 C;  4BBR C;  5FJ8 K;  3RZD C;  4A3M K;  5C4J K;  3PO2 K;  3HOW K;  3HOV K;  3S17 K;  4MEY A;  4YFK A;  3K7A C;  5IYD C;  2A6H A;  4Y52 C;  2BE5 A;  3EQL A;  2PMZ D;  4AYB D;  5C44 C;  4BY1 C;  2WAQ D;  2NVX C;  4A3B C;  3S2D C;  4G7O A;  2E2I K;  4A3I K;  2R93 K;  4LK0 A;  4A3B K;  2A6E A;  3GTG C;  3M3Y C;  1I6H K;  2B63 K;  1TWC K;  3H3V L; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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