4YFXA

Escherichia coli rna polymerase in complex with myxopyronin b
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
229
structure length
229
Chain Sequence
EFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein.
pubmed doi rcsb
source organism Escherichia coli o139:h28 (strain e24377a / etec)
molecule tags Transcription/transcription inhibitor
molecule keywords DNA-directed RNA polymerase subunit alpha
total genus 40
structure length 229
sequence length 229
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4yfxA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4yfxA01
4XSZA 5C44C 2E2JC 3RZOC 4A3CK 5TMFA 3H0GC 3M4OC 4BBRK 4A3FK 5IYCC 3HOYK 1TWCK 4KN7A 4A3GK 1WCMC 3GTMC 4JK1A 4MEYA 3S2HC 4LK0A 4A3KC 3GTKK 4A3JK 3GTGK 3S16C 5M5WK 4A93K 2WB1L 2JA8C 2PA8D 3GTOC 2B63C 4A3LK 1K83C 4AYBD 2WAQD 4QJVB 4C2MK 2O5IA 3RZDK 3HOXC 4C3HK 4Y52C 4BY1K 5IYDK 4YFKA 4A93C 3FKIK 2VUMK 1I50C 1I6VA 4A3JC 3GTGC 4GZYA 3GTKC 4X6AC 4QIWL 4OIPA 2JA6C 4XLNA 1WCMK 4QIWD 3GTMK 4A3MK 1Y1VK 5IYBK 4XSXA 1TWHK 2R7ZK 3PO3K 5C3EC 4BY7K 2JA7C 2B63K 2JA8K 2JA5K 4G7ZA 2NVXC 4YFNA 4MEXA 3S1RK 4A3DC 4MQ9A 2PA8L 1YNJA 1TWHC 5TMCA 3H3VD 1Y1VC 3S14K 3S15K 1I6HK 3GTQC 3HOYC 3S1MK 3H0GK 3K7AK 3GTPK 4OINA 3PO2K 4A3CC 2JA5C 4OIOA 3HKZL 2JA7K 2R93K 5C3EK 3RZDC 5M5XK 3HOZC 1I3QC 1SMYA 4C3JC 2E2HC 5IP7K 4Q5SA 1TWAC 3S16K 3PO2C 3GTLC 3M3YC 3EQLA 3S1QC 4BBSC 1YNNA 1TWGK 3FKIC 5M3FK 2NVQK 4BXXK 2NVYK 4C3JK 4Y52K 5IP9C 4Y7NC 2A69A 3S1NC 3CQZC 4LK1A 1TWFK 4C3IK 3DXJA 2R93C 5C4XK 3H3VL 2E2JK 4A3BK 4KMUA 4YFXA 3HOWK 3S17K 4AYBL 4A3KK 3PO3C 5IYBC 4YG2A 2CW0A 4A3MC 1R9TC 1SFOC 4A3GC 5IP9K 4Y7NK 3GTQK 2A6HA 3HOUC 1TWGC 3HKZD 4A3DK 5D4DA 2NVXK 4A3IK 5IYDC 2NVTC 4C3HC 1TWFC 3WODA 3CQZK 5C4JC 2E2IK 3S2DK 2PMZL 3I4NK 2PMZD 4X6AK 1BDFA 3GTLK 1I50K 2BE5A 4QJVA 1TWAK 4A3EK 3HOUK 5IP7C 2E2HK 3I4MK 3S2DC 2Y0SD 3GTJK 5IYCK 4G7HA 3S14C 1IW7A 2PPBA 3GTOK 5C44K 3RZOK 5FJ8K 3HOVK 4A3BC 3K7AC 3GTPC 4C3IC 2R7ZC 4OIRA 4XLPA 4G7OA 5C4XC 3S1NK 3S2HK 1HQMA 3GTJC 1TWCC 1R9TK 1SFOK 2R92K 4A3EC 3I4MC 2JA6K 3S1RC 3HOVC 2YU9C 3S17C 2VUMC 5FLMK 4BY1C 2A6EA 1I3QK 4BY7C 3HOZK 4Q4ZA 3HOXK 2Y0SL 5C4JK 4LLGA 1Y1WC 2NVYC 2A68A 4ZH4A 2NVTK 4BXXC 4A3IC 2NVQC 2WAQL 2YU9K 3M3YK 2O5JA 3S1QK 4BBSK 2WB1D 4NOIA 3I4NC 3S1MC 2R92C 1ZYRA 5M5YK 1Y1WK 2E2IC 4LJZA 3S15C 4BBRC 4A3FC 3M4OK 1I6HC 4C2MC 4OIQA 1K83K 4A3LC 5M3MK 1XPPA 4KN4A 5FLMC 3HOWC
chains in the Genus database with same CATH superfamily
5C44C 2E2JC 4LOWA 3N3YA 3H0GC 1BJTA 2ZJPS 5IYCC 4XCHA 3GEIA 3GTMC 4JK1A 4LK0A 1DCPA 3S16C 1O2FB 3LAJA 2WAQD 2O5IA 4Y52C 3MMLB 3FKIK 2VUMK 1I50C 1I6VA 4X6AC 4OIPA 4KMHA 3GTMK 3AD8C 1IBAA 1TWHK 2R7ZK 3PO3K 2B63A 4BY7K 2V6SA 5CHPA 3S14K 3S15K 1B4AA 3G4CA 3GTQC 2NVXA 3AD7C 4A3CC 3A8KA 1JVIA 2R93K 2JA7K 1JQWA 5C3EK 3RZDC 4C45A 1I50A 4Q5SA 1TWAC 3GTLC 4WJ4A 3S1QC 4BBSC 5M3FK 2NVYA 1O29A 4BXXK 1TWGA 3SZYA 1SFOA 5C4XK 4YFXA 1WCMA 1WIHA 2Y3PA 3HOWK 4AYBL 3S17K 1XZQB 4KM8A 4A3KK 4GT9A 4GTFA 5IYBC 4A3MC 4A3GC 1SFOC 3A8JA 1USOA 3N0CA 3GTPA 3HKZD 3TTGA 4P5AA 5IYDC 3GTGA 4IO9S 5C4JC 3S2DK 1GE9A 5EGEA 1K83A 3GTLK 5JVHS 2BE5A 1IL2A 1TWAK 1F93A 1WSRA 1XZQA 3GTJK 3IPJA 2PPBA 1IE0A 3QX3A 4G0WA 2L3UA 4A3BC 4C3IC 4OIRA 1TWCC 4GTAA 1DCOA 2R92K 1XZPB 3I4MC 2W7VA 4DDQA 3L4JA 2YU9C 2JA6A 4BY7C 3HOZK 3HOXK 3LAPA 1WQHA 4ZH4A 4KB2A 2D6FC 3ERED 3GTOA 4WJ3M 3BUEA 3PIOS 1ZYRA 4BKWA 1INNA 2E2IC 5JFEA 1I6HC 1XPPA 3GTJA 3G4AA 4XSZA 3RZOC 1FEUA 1TWCK 2GAGC 2JH3A 2PHCB 1EQRA 3GTGK 3DLLS 2JA7A 2WB1L 2JA8C 2PA8D 4AYBD 1UV7A 4C2MK 3HOXC 1J6VA 2GSUA 4A93C 4PABA 4A3JC 1O28A 3OPFA 1WCMK 2B63K 2R7ZA 2RGRA 1RU0A 3T02A 3JSTA 5CJ9A 4KC6A 5TMCA 1Y1VC 4O2DA 3HOYC 4WCES 1V5VA 5DM7S 3OEPA 1IQ0A 3PO2K 1DCHA 1EK8A 1TWAA 5IP7K 2ZUEA 3PO2C 3M3YC 5HL7S 1R9TA 3S1NC 3CQZC 1TWFK 3DXJA 2R93C 4LR2A 3L4KA 1XXAA 3GTMA 1WSVA 3T01A 2ZFZA 2XCQA 1R9TC 4U67S 3GTQK 4WILA 3HOUC 5IOSA 4KASA 1YCLA 3AD9C 2NVTC 1USMA 2E2IK 3TFJA 4X6AK 1I50K 4A3EK 4QJVA 4ILDA 2E2HK 3S0XA 4G7HA 3S14C 1IW7A 1O2BA 2YU9A 2V6TA 1L0WA 3RZOK 3K7AC 3PIPS 3GTPC 2R7ZC 4G7OA 1PJ6A 1EFWA 1R9TK 2CFAA 4A3EC 4M1XA 2VUMC 2A6EA 1I3QK 2ZUFA 4Q4ZA 2Y0SL 2A68A 2NVTK 2WAQL 3TFIA 3FOFA 2YU9K 3M3YK 2O5JA 4KDDA 3S1MC 2R92C 2ZJQS 3GSIA 4OIQA 3HXAA 5HL8A 4A3LC 4J3NA 5M3MK 2CFAB 5FLMC 5TMFA 3CAGA 3M4OC 3HOYK 3A8IA 1Y1VA 3BP8C 2RH6A 4A3GK 2KXYA 3S2HC 4A3KC 2GSNA 3GTKK 3CQZA 2KPUA 3AQOA 2KQ1A 2B63C 1XXCA 1HI9A 1K83C 4QJVB 1Y1WA 5JVOA 4GTBA 5IOQA 5IYDK 2ZJRS 4RMFA 1TWFA 4GZYA 3GTKC 4KMAA 1WOOA 2GAHC 4QIWL 3T00A 5IOTA 4QIWD 4A3MK 1Y1VK 2JA5A 5IYBK 5C3EC 2JA7C 2JA8K 4GTEA 2NVXC 1ZVUA 3S1RK 1YNJA 3H3VD 1BGWA 1KQ4A 1VH2A 3S1MK 4WFNS 4OINA 5JVGS 1WQGA 4PAAA 1I3QC 4BLAA 1I3QA 4WF9S 2P5MA 2XCOA 4IOAS 1YNNA 3FKIC 4C3JK 4Y52K 5IP9C 4Y7NC 2A69A 4LK1A 1O26A 2P8TA 4KMUA 1ZXOA 3PO3C 3TFHA 4YG2A 1O25A 2CW0A 2FQOA 1WQFA 2A6HA 1TWGC 4A3DK 3NUHA 5D4DA 5EGHA 3VA7A 3WODA 3FHZA 4KB4A 4P5BA 2L5NA 2PMZL 3I4NK 2PMZD 2EBBA 3I4MK 3HOUK 3S2DC 4WFBS 2GSOA 5IYCK 3GTQA 1DD5A 2KWAA 3GTOK 5C44K 3H0GA 3S1NK 3CF5S 5IORA 3GTJC 1SFOK 4AH6A 2JA6K 3S1RC 3HOVC 1PJ7A 2FQTA 4FZBA 3S17C 2R92A 4BY1C 5C4JK 4LLGA 1Y1WC 1EH1A 1C0AA 4BXXC 3S1QK 4BBSK 1VRQC 3LPXA 1B4BA 3GIRA 4GFQA 2WB1D 1YX2A 4NOIA 1Y1WK 4LJZA 4BBRC 4A3FC 1ISEA 1K83K 4KN4A 3HOWC 5L46A 2XCRB 1O27A 4A3CK 4BBRK 4A3FK 1ZQ1C 4KN7A 1TWHA 5HQHA 1WCMC 4MEYA 4A3JK 1J6XA 1VGXA 5M5WK 4IOCS 4A93K 3GTOC 4A3LK 3FKIA 3RZDK 3OREA 4C3HK 4BY1K 4YFKA 3GDZA 3GTGC 2JA6C 1ZBSA 4XLNA 1TWCA 1J98A 4XSXA 3SZZA 2JA5K 4G7ZA 4YFNA 4MEXA 4GTDA 4A3DC 4MQ9A 2PA8L 1I6HK 1TWHC 3H0GK 3K7AK 3GTPK 3AQPA 4G0VA 2JA5C 4OIOA 1WOPA 3HKZL 4GTLA 1AB4A 1BS2A 5M5XK 1PJ5A 3HOZC 3GTKA 2E2HA 1SMYA 4C3JC 1WORA 2E2HC 1VJEA 3S16K 4KAWX 2NVQK 3EQLA 1TWGK 1F7UA 5DM6S 2NVYK 1JOEA 2V6UA 4C3IK 4A3BK 3H3VL 2VUMA 2E2JK 5TJ3A 1G51A 4BLBA 3Q3QA 2R93A 5IP9K 4Y7NK 4GTCA 1X31C 2NVXK 4A3IK 3GTLA 4WFAS 4C3HC 1TWFC 3CQZK 1XZPA 3GEEA 1O24A 4KARA 4KMDA 1BDFA 5IP7C 3BP3A 1EI6A 3N0BA 2Y0SD 3AH5A 4LQYA 1IS1A 4KATA 1XXBA 5FJ8K 3FOEA 3HOVK 1O2AA 5C4XC 3S2HK 3LYWA 4XLPA 1HQMA 1F9NA 4P9SA 2E2IA 3ADAC 1VLOA 5FLMK 1WOSA 3GEHA 4FM9A 2NVYC 4A3IC 2NVQC 5E68A 4G0UA 3V4GA 1F7VA 3I4NC 4KM9A 5M5YK 3S15C 3M4OK 4C2MC 1J6WA
chains in the Genus database with same CATH topology
4XSZA 5C44C 2E2JC 3RZOC 4A3CK 5TMFA 3H0GC 3M4OC 4BBRK 4A3FK 5IYCC 3HOYK 1TWCK 4KN7A 4A3GK 1WCMC 3GTMC 4JK1A 4MEYA 3S2HC 4LK0A 4A3KC 3GTKK 4A3JK 3GTGK 3S16C 5M5WK 4A93K 2WB1L 2JA8C 2PA8D 3GTOC 2B63C 4A3LK 1K83C 4AYBD 2WAQD 4QJVB 4C2MK 2O5IA 3RZDK 3HOXC 4C3HK 4Y52C 4BY1K 5IYDK 4YFKA 4A93C 3FKIK 2VUMK 1I50C 1I6VA 4A3JC 3GTGC 4GZYA 3GTKC 4X6AC 4QIWL 4OIPA 2JA6C 4XLNA 1WCMK 4QIWD 3GTMK 4A3MK 1Y1VK 5IYBK 4XSXA 1TWHK 2R7ZK 3PO3K 5C3EC 4BY7K 2JA7C 2B63K 2JA8K 2JA5K 4G7ZA 2NVXC 4YFNA 4MEXA 3S1RK 4A3DC 4MQ9A 2PA8L 1YNJA 1TWHC 5TMCA 3H3VD 1Y1VC 3S14K 3S15K 1I6HK 3GTQC 3HOYC 3S1MK 3H0GK 3K7AK 3GTPK 4OINA 3PO2K 4A3CC 2JA5C 4OIOA 3HKZL 2JA7K 2R93K 5C3EK 3RZDC 5M5XK 3HOZC 1I3QC 1SMYA 4C3JC 2E2HC 5IP7K 4Q5SA 1TWAC 3S16K 3PO2C 3GTLC 3M3YC 3EQLA 3S1QC 4BBSC 1YNNA 1TWGK 3FKIC 5M3FK 2NVQK 4BXXK 2NVYK 4C3JK 4Y52K 5IP9C 4Y7NC 2A69A 3S1NC 3CQZC 4LK1A 1TWFK 4C3IK 3DXJA 2R93C 5C4XK 3H3VL 2E2JK 4A3BK 4KMUA 4YFXA 3HOWK 3S17K 4AYBL 4A3KK 3PO3C 5IYBC 4YG2A 2CW0A 4A3MC 1R9TC 1SFOC 4A3GC 5IP9K 4Y7NK 3GTQK 2A6HA 3HOUC 1TWGC 3HKZD 4A3DK 5D4DA 2NVXK 4A3IK 5IYDC 2NVTC 4C3HC 1TWFC 3WODA 3CQZK 5C4JC 2E2IK 3S2DK 2PMZL 3I4NK 2PMZD 4X6AK 1BDFA 3GTLK 1I50K 2BE5A 4QJVA 1TWAK 4A3EK 3HOUK 5IP7C 2E2HK 3I4MK 3S2DC 2Y0SD 3GTJK 5IYCK 4G7HA 3S14C 1IW7A 2PPBA 3GTOK 5C44K 3RZOK 5FJ8K 3HOVK 4A3BC 3K7AC 3GTPC 4C3IC 2R7ZC 4OIRA 4XLPA 4G7OA 5C4XC 3S1NK 3S2HK 1HQMA 3GTJC 1TWCC 1R9TK 1SFOK 2R92K 4A3EC 3I4MC 2JA6K 3S1RC 3HOVC 2YU9C 3S17C 2VUMC 5FLMK 4BY1C 2A6EA 1I3QK 4BY7C 3HOZK 4Q4ZA 3HOXK 2Y0SL 5C4JK 4LLGA 1Y1WC 2NVYC 2A68A 4ZH4A 2NVTK 4BXXC 4A3IC 2NVQC 2WAQL 2YU9K 3M3YK 2O5JA 3S1QK 4BBSK 2WB1D 4NOIA 3I4NC 3S1MC 2R92C 1ZYRA 5M5YK 1Y1WK 2E2IC 4LJZA 3S15C 4BBRC 4A3FC 3M4OK 1I6HC 4C2MC 4OIQA 1K83K 4A3LC 5M3MK 1XPPA 4KN4A 5FLMC 3HOWC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XSZ A;  5C44 C;  2E2J C;  3RZO C;  4A3C K;  5TMF A;  3H0G C;  3M4O C;  4BBR K;  4A3F K;  5IYC C;  3HOY K;  1TWC K;  4KN7 A;  4A3G K;  1WCM C;  3GTM C;  4JK1 A;  4MEY A;  3S2H C;  4LK0 A;  4A3K C;  3GTK K;  4A3J K;  3GTG K;  3S16 C;  5M5W K;  4A93 K;  2WB1 L;  2JA8 C;  2PA8 D;  3GTO C;  2B63 C;  4A3L K;  1K83 C;  4AYB D;  2WAQ D;  4QJV B;  4C2M K;  2O5I A;  3RZD K;  3HOX C;  4C3H K;  4Y52 C;  4BY1 K;  5IYD K;  4YFK A;  4A93 C;  3FKI K;  2VUM K;  1I50 C;  1I6V A;  4A3J C;  3GTG C;  4GZY A;  3GTK C;  4X6A C;  4QIW L;  4OIP A;  2JA6 C;  4XLN A;  1WCM K;  4QIW D;  3GTM K;  4A3M K;  1Y1V K;  5IYB K;  4XSX A;  1TWH K;  2R7Z K;  3PO3 K;  5C3E C;  4BY7 K;  2JA7 C;  2B63 K;  2JA8 K;  2JA5 K;  4G7Z A;  2NVX C;  4YFN A;  4MEX A;  3S1R K;  4A3D C;  4MQ9 A;  2PA8 L;  1YNJ A;  1TWH C;  5TMC A;  3H3V D;  1Y1V C;  3S14 K;  3S15 K;  1I6H K;  3GTQ C;  3HOY C;  3S1M K;  3H0G K;  3K7A K;  3GTP K;  4OIN A;  3PO2 K;  4A3C C;  2JA5 C;  4OIO A;  3HKZ L;  2JA7 K;  2R93 K;  5C3E K;  3RZD C;  5M5X K;  3HOZ C;  1I3Q C;  1SMY A;  4C3J C;  2E2H C;  5IP7 K;  4Q5S A;  1TWA C;  3S16 K;  3PO2 C;  3GTL C;  3M3Y C;  3EQL A;  3S1Q C;  4BBS C;  1YNN A;  1TWG K;  3FKI C;  5M3F K;  2NVQ K;  4BXX K;  2NVY K;  4C3J K;  4Y52 K;  5IP9 C;  4Y7N C;  2A69 A;  3S1N C;  3CQZ C;  4LK1 A;  1TWF K;  4C3I K;  3DXJ A;  2R93 C;  5C4X K;  3H3V L;  2E2J K;  4A3B K;  4KMU A;  4YFX A;  3HOW K;  3S17 K;  4AYB L;  4A3K K;  3PO3 C;  5IYB C;  4YG2 A;  2CW0 A;  4A3M C;  1R9T C;  1SFO C;  4A3G C;  5IP9 K;  4Y7N K;  3GTQ K;  2A6H A;  3HOU C;  1TWG C;  3HKZ D;  4A3D K;  5D4D A;  2NVX K;  4A3I K;  5IYD C;  2NVT C;  4C3H C;  1TWF C;  3WOD A;  3CQZ K;  5C4J C;  2E2I K;  3S2D K;  2PMZ L;  3I4N K;  2PMZ D;  4X6A K;  1BDF A;  3GTL K;  1I50 K;  2BE5 A;  4QJV A;  1TWA K;  4A3E K;  3HOU K;  5IP7 C;  2E2H K;  3I4M K;  3S2D C;  2Y0S D;  3GTJ K;  5IYC K;  4G7H A;  3S14 C;  1IW7 A;  2PPB A;  3GTO K;  5C44 K;  3RZO K;  5FJ8 K;  3HOV K;  4A3B C;  3K7A C;  3GTP C;  4C3I C;  2R7Z C;  4OIR A;  4XLP A;  4G7O A;  5C4X C;  3S1N K;  3S2H K;  1HQM A;  3GTJ C;  1TWC C;  1R9T K;  1SFO K;  2R92 K;  4A3E C;  3I4M C;  2JA6 K;  3S1R C;  3HOV C;  2YU9 C;  3S17 C;  2VUM C;  5FLM K;  4BY1 C;  2A6E A;  1I3Q K;  4BY7 C;  3HOZ K;  4Q4Z A;  3HOX K;  2Y0S L;  5C4J K;  4LLG A;  1Y1W C;  2NVY C;  2A68 A;  4ZH4 A;  2NVT K;  4BXX C;  4A3I C;  2NVQ C;  2WAQ L;  2YU9 K;  3M3Y K;  2O5J A;  3S1Q K;  4BBS K;  2WB1 D;  4NOI A;  3I4N C;  3S1M C;  2R92 C;  1ZYR A;  5M5Y K;  1Y1W K;  2E2I C;  4LJZ A;  3S15 C;  4BBR C;  4A3F C;  3M4O K;  1I6H C;  4C2M C;  4OIQ A;  1K83 K;  4A3L C;  5M3M K;  1XPP A;  4KN4 A;  5FLM C;  3HOW C; 
#chains in the Genus database with same CATH topology
 5C44 C;  2E2J C;  4LOW A;  3N3Y A;  3H0G C;  1BJT A;  2ZJP S;  5IYC C;  4XCH A;  3GEI A;  3GTM C;  4JK1 A;  4LK0 A;  1DCP A;  3S16 C;  1O2F B;  3LAJ A;  2WAQ D;  2O5I A;  4Y52 C;  3MML B;  3FKI K;  2VUM K;  1I50 C;  1I6V A;  4X6A C;  4OIP A;  4KMH A;  3GTM K;  3AD8 C;  1IBA A;  1TWH K;  2R7Z K;  3PO3 K;  2B63 A;  4BY7 K;  2V6S A;  5CHP A;  3S14 K;  3S15 K;  1B4A A;  3G4C A;  3GTQ C;  2NVX A;  3AD7 C;  4A3C C;  3A8K A;  1JVI A;  2R93 K;  2JA7 K;  1JQW A;  5C3E K;  3RZD C;  4C45 A;  1I50 A;  4Q5S A;  1TWA C;  3GTL C;  4WJ4 A;  3S1Q C;  4BBS C;  5M3F K;  2NVY A;  1O29 A;  4BXX K;  1TWG A;  3SZY A;  1SFO A;  5C4X K;  4YFX A;  1WCM A;  1WIH A;  2Y3P A;  3HOW K;  4AYB L;  3S17 K;  1XZQ B;  4KM8 A;  4A3K K;  4GT9 A;  4GTF A;  5IYB C;  4A3M C;  4A3G C;  1SFO C;  3A8J A;  1USO A;  3N0C A;  3GTP A;  3HKZ D;  3TTG A;  4P5A A;  5IYD C;  3GTG A;  4IO9 S;  5C4J C;  3S2D K;  1GE9 A;  5EGE A;  1K83 A;  3GTL K;  5JVH S;  2BE5 A;  1IL2 A;  1TWA K;  1F93 A;  1WSR A;  1XZQ A;  3GTJ K;  3IPJ A;  2PPB A;  1IE0 A;  3QX3 A;  4G0W A;  2L3U A;  4A3B C;  4C3I C;  4OIR A;  1TWC C;  4GTA A;  1DCO A;  2R92 K;  1XZP B;  3I4M C;  2W7V A;  4DDQ A;  3L4J A;  2YU9 C;  2JA6 A;  4BY7 C;  3HOZ K;  3HOX K;  3LAP A;  1WQH A;  4ZH4 A;  4KB2 A;  2D6F C;  3ERE D;  3GTO A;  4WJ3 M;  3BUE A;  3PIO S;  1ZYR A;  4BKW A;  1INN A;  2E2I C;  5JFE A;  1I6H C;  1XPP A;  3GTJ A;  3G4A A;  4XSZ A;  3RZO C;  1FEU A;  1TWC K;  2GAG C;  2JH3 A;  2PHC B;  1EQR A;  3GTG K;  3DLL S;  2JA7 A;  2WB1 L;  2JA8 C;  2PA8 D;  4AYB D;  1UV7 A;  4C2M K;  3HOX C;  1J6V A;  2GSU A;  4A93 C;  4PAB A;  4A3J C;  1O28 A;  3OPF A;  1WCM K;  2B63 K;  2R7Z A;  2RGR A;  1RU0 A;  3T02 A;  3JST A;  5CJ9 A;  4KC6 A;  5TMC A;  1Y1V C;  4O2D A;  3HOY C;  4WCE S;  1V5V A;  5DM7 S;  3OEP A;  1IQ0 A;  3PO2 K;  1DCH A;  1EK8 A;  1TWA A;  5IP7 K;  2ZUE A;  3PO2 C;  3M3Y C;  5HL7 S;  1R9T A;  3S1N C;  3CQZ C;  1TWF K;  3DXJ A;  2R93 C;  4LR2 A;  3L4K A;  1XXA A;  3GTM A;  1WSV A;  3T01 A;  2ZFZ A;  2XCQ A;  1R9T C;  4U67 S;  3GTQ K;  4WIL A;  3HOU C;  5IOS A;  4KAS A;  1YCL A;  3AD9 C;  2NVT C;  1USM A;  2E2I K;  3TFJ A;  4X6A K;  1I50 K;  4A3E K;  4QJV A;  4ILD A;  2E2H K;  3S0X A;  4G7H A;  3S14 C;  1IW7 A;  1O2B A;  2YU9 A;  2V6T A;  1L0W A;  3RZO K;  3K7A C;  3PIP S;  3GTP C;  2R7Z C;  4G7O A;  1PJ6 A;  1EFW A;  1R9T K;  2CFA A;  4A3E C;  4M1X A;  2VUM C;  2A6E A;  1I3Q K;  2ZUF A;  4Q4Z A;  2Y0S L;  2A68 A;  2NVT K;  2WAQ L;  3TFI A;  3FOF A;  2YU9 K;  3M3Y K;  2O5J A;  4KDD A;  3S1M C;  2R92 C;  2ZJQ S;  3GSI A;  4OIQ A;  3HXA A;  5HL8 A;  4A3L C;  4J3N A;  5M3M K;  2CFA B;  5FLM C;  5TMF A;  3CAG A;  3M4O C;  3HOY K;  3A8I A;  1Y1V A;  3BP8 C;  2RH6 A;  4A3G K;  2KXY A;  3S2H C;  4A3K C;  2GSN A;  3GTK K;  3CQZ A;  2KPU A;  3AQO A;  2KQ1 A;  2B63 C;  1XXC A;  1HI9 A;  1K83 C;  4QJV B;  1Y1W A;  5JVO A;  4GTB A;  5IOQ A;  5IYD K;  2ZJR S;  4RMF A;  1TWF A;  4GZY A;  3GTK C;  4KMA A;  1WOO A;  2GAH C;  4QIW L;  3T00 A;  5IOT A;  4QIW D;  4A3M K;  1Y1V K;  2JA5 A;  5IYB K;  5C3E C;  2JA7 C;  2JA8 K;  4GTE A;  2NVX C;  1ZVU A;  3S1R K;  1YNJ A;  3H3V D;  1BGW A;  1KQ4 A;  1VH2 A;  3S1M K;  4WFN S;  4OIN A;  5JVG S;  1WQG A;  4PAA A;  1I3Q C;  4BLA A;  1I3Q A;  4WF9 S;  2P5M A;  2XCO A;  4IOA S;  1YNN A;  3FKI C;  4C3J K;  4Y52 K;  5IP9 C;  4Y7N C;  2A69 A;  4LK1 A;  1O26 A;  2P8T A;  4KMU A;  1ZXO A;  3PO3 C;  3TFH A;  4YG2 A;  1O25 A;  2CW0 A;  2FQO A;  1WQF A;  2A6H A;  1TWG C;  4A3D K;  3NUH A;  5D4D A;  5EGH A;  3VA7 A;  3WOD A;  3FHZ A;  4KB4 A;  4P5B A;  2L5N A;  2PMZ L;  3I4N K;  2PMZ D;  2EBB A;  3I4M K;  3HOU K;  3S2D C;  4WFB S;  2GSO A;  5IYC K;  3GTQ A;  1DD5 A;  2KWA A;  3GTO K;  5C44 K;  3H0G A;  3S1N K;  3CF5 S;  5IOR A;  3GTJ C;  1SFO K;  4AH6 A;  2JA6 K;  3S1R C;  3HOV C;  1PJ7 A;  2FQT A;  4FZB A;  3S17 C;  2R92 A;  4BY1 C;  5C4J K;  4LLG A;  1Y1W C;  1EH1 A;  1C0A A;  4BXX C;  3S1Q K;  4BBS K;  1VRQ C;  3LPX A;  1B4B A;  3GIR A;  4GFQ A;  2WB1 D;  1YX2 A;  4NOI A;  1Y1W K;  4LJZ A;  4BBR C;  4A3F C;  1ISE A;  1K83 K;  4KN4 A;  3HOW C;  5L46 A;  2XCR B;  1O27 A;  4A3C K;  4BBR K;  4A3F K;  1ZQ1 C;  4KN7 A;  1TWH A;  5HQH A;  1WCM C;  4MEY A;  4A3J K;  1J6X A;  1VGX A;  5M5W K;  4IOC S;  4A93 K;  3GTO C;  4A3L K;  3FKI A;  3RZD K;  3ORE A;  4C3H K;  4BY1 K;  4YFK A;  3GDZ A;  3GTG C;  2JA6 C;  1ZBS A;  4XLN A;  1TWC A;  1J98 A;  4XSX A;  3SZZ A;  2JA5 K;  4G7Z A;  4YFN A;  4MEX A;  4GTD A;  4A3D C;  4MQ9 A;  2PA8 L;  1I6H K;  1TWH C;  3H0G K;  3K7A K;  3GTP K;  3AQP A;  4G0V A;  2JA5 C;  4OIO A;  1WOP A;  3HKZ L;  4GTL A;  1AB4 A;  1BS2 A;  5M5X K;  1PJ5 A;  3HOZ C;  3GTK A;  2E2H A;  1SMY A;  4C3J C;  1WOR A;  2E2H C;  1VJE A;  3S16 K;  4KAW X;  2NVQ K;  3EQL A;  1TWG K;  1F7U A;  5DM6 S;  2NVY K;  1JOE A;  2V6U A;  4C3I K;  4A3B K;  3H3V L;  2VUM A;  2E2J K;  5TJ3 A;  1G51 A;  4BLB A;  3Q3Q A;  2R93 A;  5IP9 K;  4Y7N K;  4GTC A;  1X31 C;  2NVX K;  4A3I K;  3GTL A;  4WFA S;  4C3H C;  1TWF C;  3CQZ K;  1XZP A;  3GEE A;  1O24 A;  4KAR A;  4KMD A;  1BDF A;  5IP7 C;  3BP3 A;  1EI6 A;  3N0B A;  2Y0S D;  3AH5 A;  4LQY A;  1IS1 A;  4KAT A;  1XXB A;  5FJ8 K;  3FOE A;  3HOV K;  1O2A A;  5C4X C;  3S2H K;  3LYW A;  4XLP A;  1HQM A;  1F9N A;  4P9S A;  2E2I A;  3ADA C;  1VLO A;  5FLM K;  1WOS A;  3GEH A;  4FM9 A;  2NVY C;  4A3I C;  2NVQ C;  5E68 A;  4G0U A;  3V4G A;  1F7V A;  3I4N C;  4KM9 A;  5M5Y K;  3S15 C;  3M4O K;  4C2M C;  1J6W A; 
#chains in the Genus database with same CATH homology
 4XSZ A;  5C44 C;  2E2J C;  3RZO C;  4A3C K;  5TMF A;  3H0G C;  3M4O C;  4BBR K;  4A3F K;  5IYC C;  3HOY K;  1TWC K;  4KN7 A;  4A3G K;  1WCM C;  3GTM C;  4JK1 A;  4MEY A;  3S2H C;  4LK0 A;  4A3K C;  3GTK K;  4A3J K;  3GTG K;  3S16 C;  5M5W K;  4A93 K;  2WB1 L;  2JA8 C;  2PA8 D;  3GTO C;  2B63 C;  4A3L K;  1K83 C;  4AYB D;  2WAQ D;  4QJV B;  4C2M K;  2O5I A;  3RZD K;  3HOX C;  4C3H K;  4Y52 C;  4BY1 K;  5IYD K;  4YFK A;  4A93 C;  3FKI K;  2VUM K;  1I50 C;  1I6V A;  4A3J C;  3GTG C;  4GZY A;  3GTK C;  4X6A C;  4QIW L;  4OIP A;  2JA6 C;  4XLN A;  1WCM K;  4QIW D;  3GTM K;  4A3M K;  1Y1V K;  5IYB K;  4XSX A;  1TWH K;  2R7Z K;  3PO3 K;  5C3E C;  4BY7 K;  2JA7 C;  2B63 K;  2JA8 K;  2JA5 K;  4G7Z A;  2NVX C;  4YFN A;  4MEX A;  3S1R K;  4A3D C;  4MQ9 A;  2PA8 L;  1YNJ A;  1TWH C;  5TMC A;  3H3V D;  1Y1V C;  3S14 K;  3S15 K;  1I6H K;  3GTQ C;  3HOY C;  3S1M K;  3H0G K;  3K7A K;  3GTP K;  4OIN A;  3PO2 K;  4A3C C;  2JA5 C;  4OIO A;  3HKZ L;  2JA7 K;  2R93 K;  5C3E K;  3RZD C;  5M5X K;  3HOZ C;  1I3Q C;  1SMY A;  4C3J C;  2E2H C;  5IP7 K;  4Q5S A;  1TWA C;  3S16 K;  3PO2 C;  3GTL C;  3M3Y C;  3EQL A;  3S1Q C;  4BBS C;  1YNN A;  1TWG K;  3FKI C;  5M3F K;  2NVQ K;  4BXX K;  2NVY K;  4C3J K;  4Y52 K;  5IP9 C;  4Y7N C;  2A69 A;  3S1N C;  3CQZ C;  4LK1 A;  1TWF K;  4C3I K;  3DXJ A;  2R93 C;  5C4X K;  3H3V L;  2E2J K;  4A3B K;  4KMU A;  4YFX A;  3HOW K;  3S17 K;  4AYB L;  4A3K K;  3PO3 C;  5IYB C;  4YG2 A;  2CW0 A;  4A3M C;  1R9T C;  1SFO C;  4A3G C;  5IP9 K;  4Y7N K;  3GTQ K;  2A6H A;  3HOU C;  1TWG C;  3HKZ D;  4A3D K;  5D4D A;  2NVX K;  4A3I K;  5IYD C;  2NVT C;  4C3H C;  1TWF C;  3WOD A;  3CQZ K;  5C4J C;  2E2I K;  3S2D K;  2PMZ L;  3I4N K;  2PMZ D;  4X6A K;  1BDF A;  3GTL K;  1I50 K;  2BE5 A;  4QJV A;  1TWA K;  4A3E K;  3HOU K;  5IP7 C;  2E2H K;  3I4M K;  3S2D C;  2Y0S D;  3GTJ K;  5IYC K;  4G7H A;  3S14 C;  1IW7 A;  2PPB A;  3GTO K;  5C44 K;  3RZO K;  5FJ8 K;  3HOV K;  4A3B C;  3K7A C;  3GTP C;  4C3I C;  2R7Z C;  4OIR A;  4XLP A;  4G7O A;  5C4X C;  3S1N K;  3S2H K;  1HQM A;  3GTJ C;  1TWC C;  1R9T K;  1SFO K;  2R92 K;  4A3E C;  3I4M C;  2JA6 K;  3S1R C;  3HOV C;  2YU9 C;  3S17 C;  2VUM C;  5FLM K;  4BY1 C;  2A6E A;  1I3Q K;  4BY7 C;  3HOZ K;  4Q4Z A;  3HOX K;  2Y0S L;  5C4J K;  4LLG A;  1Y1W C;  2NVY C;  2A68 A;  4ZH4 A;  2NVT K;  4BXX C;  4A3I C;  2NVQ C;  2WAQ L;  2YU9 K;  3M3Y K;  2O5J A;  3S1Q K;  4BBS K;  2WB1 D;  4NOI A;  3I4N C;  3S1M C;  2R92 C;  1ZYR A;  5M5Y K;  1Y1W K;  2E2I C;  4LJZ A;  3S15 C;  4BBR C;  4A3F C;  3M4O K;  1I6H C;  4C2M C;  4OIQ A;  1K83 K;  4A3L C;  5M3M K;  1XPP A;  4KN4 A;  5FLM C;  3HOW C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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