1K83C

Crystal structure of yeast rna polymerase ii complexed with the inhibitor alpha amanitin
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
publication title Structural Basis of Transcription: Alpha-Amanitin-RNA Polymerase II Cocrystal at 2.8 A Resolution.
pubmed doi rcsb
molecule tags Transcription/toxin
total genus 59
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2001-10-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 1k83C01
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 1k83C02
4OIRA 1TWHK 2E2HC 1ZYRA 2E2IK 1TWFC 4AYBD 3PO2K 3S1NK 3HOZK 2R7ZK 2NVTK 3GTGK 1TWCK 3S1RK 2R92C 4A3BC 3S2HK 5M5XK 1I6VA 2JA5C 1TWFK 2VUMC 2PMZD 4A3EK 3CQZC 4BY7K 4A3KK 3GTPK 4YFNA 4Y7NC 2A69A 4XSZA 3FKIC 3S15C 4YFXA 4XSXA 1Y1VC 3HOXK 4AYBL 3RZOK 1TWGC 4KMUA 4OIPA 3RZDC 3S16C 2E2JK 3GTMC 4Y7NK 4A3LK 3S17C 1YNNA 4A93C 4LJZA 4G7ZA 4GZYA 5IYCC 5IP9C 2JA8C 4A3CC 2B63C 3S15K 4X6AK 5M5WK 4BBRC 1YNJA 5TMCA 4XLNA 5C3EK 2Y0SL 2A68A 5FLMK 2NVQK 3GTOK 1K83C 4JK1A 4BBSC 2BE5A 3S14K 5IYBK 2WAQD 2NVXK 4C2MC 1I3QC 4A3DC 1TWAK 2O5JA 4KN7A 4LLGA 3WODA 3HOVK 2NVYC 4YG2A 3HOYC 1I50C 2E2HK 2A6HA 2JA6C 2YU9C 4C3IC 1WCMC 4Q5SA 4C3HC 1BDFA 3K7AC 1I50K 2Y0SD 5C4XC 2WAQL 2R92K 2WB1D 4A3BK 1Y1WC 2JA5K 2VUMK 4QIWL 4XLPA 3S1MC 4A3MC 4YFKA 4BY1C 4OIQA 3CQZK 3S2DC 1SMYA 3GTLC 3HKZL 1Y1WK 2CW0A 3FKIK 3HOWC 1Y1VK 3H0GC 5FJ8K 4BY1K 1TWGK 4A3FC 3RZDK 3GTQC 3S16K 3GTMK 3GTKC 3PO3C 5C44C 2WB1L 3S17K 3M4OK 4A3CK 4A93K 5IYCK 5IP9K 2JA8K 1I6HC 2B63K 5IP7C 4A3JC 4BBRK 4Y52C 4QIWD 2O5IA 3H3VL 2R93C 5C4JC 4QJVB 3M3YC 1K83K 4BBSK 4MQ9A 3GTJC 4OINA 4C2MK 3HKZD 1I3QK 5IP7K 4A3DK 3HOUC 1IW7A 4MEXA 4NOIA 2JA7C 1R9TC 2NVYK 3HOYK 4G7OA 2JA6K 2YU9K 3I4NC 3M4OC 3S1QC 4C3IK 1WCMK 5M3FK 1TWHC 4C3HK 4BXXC 2A6EA 3K7AK 3H3VD 5M5YK 5C4XK 4A3GC 4OIOA 3PO2C 3S1NC 4G7HA 3HOZC 2PA8L 2R7ZC 3S1MK 4ZH4A 2NVTC 3GTGC 1TWCC 4C3JC 3S1RC 3S2HC 4A3MK 3HOVC 4BXXK 3DXJA 3S2DK 3GTLK 4LK1A 4KN4A 4A3GK 4A3EC 3HOWK 4BY7C 4QJVA 5D4DA 4A3KC 3GTPC 3H0GK 4C3JK 4A3FK 1SFOC 3GTQK 3GTKK 5M3MK 5C44K 3HOXC 3I4MC 3PO3K 3RZOC 1I6HK 4A3JK 2E2JC 4A3LC 4Y52K 2PA8D 1SFOK 4X6AC 3S1QK 4LK0A 5C4JK 3M3YK 2R93K 3I4MK 4A3IC 5IYDC 3EQLA 4Q4ZA 2PPBA 3GTJK 5C3EC 2NVQC 3S14C 5FLMC 3GTOC 3HOUK 5IYBC 1HQMA 2E2IC 2PMZL 2NVXC 1R9TK 2JA7K 4A3IK 1TWAC 4MEYA 5IYDK 3I4NK 1XPPA 5TMFA
chains in the Genus database with same CATH superfamily
3AH5A 1ZYRA 1V5VA 2ZUEA 2NVTK 1BJTA 1TWCK 5IOSA 5M5XK 3G4AA 2PMZD 4A3EK 1O28A 3Q3QA 3A8JA 4A3KK 4YFNA 3FKIC 4KMAA 4YFXA 4XSXA 3L4KA 1EQRA 4KMUA 4BKWA 2GAGC 4A3LK 4Y7NK 4KMDA 1YNNA 4LJZA 4A3CC 1DD5A 4DDQA 4X6AK 2B63C 1SFOA 4P5AA 1L0WA 4BBRC 5M5WK 1YNJA 3OREA 3GTOK 4JK1A 2BE5A 2WAQD 1J6WA 4WCES 3N3YA 4U67S 4WF9S 2O5JA 4P5BA 4GTDA 3HOYC 4GTCA 1WQHA 2YU9C 4Q5SA 2P5MA 3N0CA 1XXBA 2EBBA 2WB1D 1WIHA 3GTGA 3T02A 4XLPA 1YCLA 1TWFA 2PHCB 3S2DC 3GTLC 4KMHA 4P9SA 2CW0A 3FKIK 3H0GC 5HL7S 3LYWA 4A3CK 4WILA 2B63K 4BBRK 4Y52C 3H3VL 5C4JC 1J98A 3GTJC 4OINA 2V6UA 3ADAC 2KPUA 4MEXA 3HOYK 1K83A 2YU9K 5E68A 1TWHC 3H3VD 2NVYA 3S1NC 2PA8L 2R7ZC 4ZH4A 2JA5A 3BP3A 3S2HC 3S2DK 3GTLK 4LK1A 4KN4A 1VH2A 4A3GK 3GEHA 3H0GK 1IE0A 4C3JK 1TWGA 3RZOC 2D6FC 4WJ4A 4KARA 3AQOA 4Y52K 2PA8D 5C4JK 3GEEA 3GTJK 1BS2A 5C3EC 2NVQC 4J3NA 5HL8A 2R93A 1TWAC 1O2FB 5EGEA 3HOVC 1TWHK 2E2HC 2E2IK 3DLLS 3PIOS 2JA7A 4BLAA 3S1NK 1BGWA 2R7ZK 3S2HK 2R92C 4A3BC 1F93A 4GTFA 4G0VA 4Y7NC 1TWCA 1VJEA 3RZOK 3GTKA 3T01A 3RZDC 3GTMC 4WJ3M 4A93C 4GZYA 5TMCA 5C3EK 2NVQK 4GTLA 2KXYA 1I3QC 4A3DC 1TWAK 3GIRA 4KB4A 3HOVK 1JVIA 2E2HK 2A6HA 2JA6C 1WCMC 3K7AC 1I50K 5C4XC 2WAQL 3OEPA 3FOEA 2R92K 4A3BK 3IPJA 3S1MC 3TFJA 4A3MC 4OIQA 1B4AA 1SMYA 1WSRA 1IBAA 2L3UA 1Y1WK 3GTPA 1ZXOA 1O26A 2ZUFA 4BY1K 4A3FC 3RZDK 3GTQC 3GTMK 2WB1L 4A93K 3FKIA 4A3JC 2O5IA 1HI9A 4G0WA 1G51A 1I3QK 5IP7K 4A3DK 2NVXA 3HOUC 1ISEA 2XCRB 3A8IA 4IO9S 3NUHA 2GAHC 4G7OA 2JA6K 1J6XA 1DCOA 1WCMK 3GEIA 1O29A 1INNA 3K7AK 2V6SA 5C4XK 4A3GC 3TTGA 3HOZC 3S1MK 4A3MK 3GTGC 4C3JC 2VUMA 1EK8A 2KWAA 3DXJA 3MMLB 3CQZA 4G0UA 4GTEA 1Y1VA 1PJ7A 5DM6S 2GSUA 4A3FK 3GTQK 2RH6A 3BP8C 4A3JK 2E2JC 3H0GA 1SFOK 4LK0A 4KC6A 3ERED 3EQLA 2PPBA 3SZYA 5FLMC 3HOUK 5IYBC 2E2IC 4MEYA 4KB2A 4FZBA 1WOOA 3GTJA 5TMFA 5JFEA 1O2AA 5IORA 4AYBD 5IOQA 4ILDA 5EGHA 3HOZK 1EH1A 3GTGK 1TWHA 3V4GA 5JVGS 2JA5C 1TWFK 4KDDA 3CF5S 1F7VA 2JH3A 3CAGA 1IL2A 3GSIA 2A69A 4XSZA 3TFIA 5HQHA 4KM9A 1TWGC 4OIPA 3S16C 2FQOA 2E2JK 4GT9A 3S17C 3S15K 5IP9C 5TJ3A 1ZBSA 4XLNA 4AH6A 2Y0SL 2A68A 5FLMK 4BBSC 5IYBK 3GDZA 1R9TA 1JQWA 4M1XA 4KN7A 4LLGA 3LAJA 3WODA 1I50C 4FM9A 3HXAA 2RGRA 4LQYA 1TWAA 1C0AA 4KATA 4C3HC 2Y0SD 1ZVUA 1Y1WC 2JA5K 4C45A 3L4JA 4YFKA 4BY1C 1O25A 3FHZA 4RMFA 4XCHA 3HKZL 2R92A 5FJ8K 1TWGK 3S16K 3GTKC 3S17K 5IP9K 1I6HC 5IP7C 1WOSA 1O27A 5CJ9A 2P8TA 2V6TA 3M3YC 1DCPA 4QJVB 4BBSK 3GTOA 3HKZD 5DM7S 2KQ1A 1GE9A 4GTBA 1IW7A 1WSVA 4GFQA 1RU0A 3S0XA 3I4NC 4IOCS 3M4OC 3S1QC 1I3QA 4C3HK 2GSNA 4OIOA 3PO2C 4G7HA 1XZPB 1WCMA 4BXXK 3S1RC 4LOWA 1EFWA 1O2BA 5L46A 4BY7C 4QJVA 5D4DA 3GTPC 4O2DA 3VA7A 1USOA 1SFOC 3SZZA 3GTKK 3HOXC 1AB4A 3TFHA 1I6HK 2B63A 3M3YK 3I4MK 2W7VA 3GTQA 4Q4ZA 4KAWX 3S14C 4WFNS 3T00A 1IQ0A 2NVXC 4A3IK 1XZPA 1KQ4A 1F9NA 3AQPA 5IYDK 3I4NK 1XPPA 4IOAS 1ZQ1C 3M4OK 3S1QK 2YU9A 4OIRA 3JSTA 4PABA 3BUEA 1TWFC 1DCHA 3PO2K 3LAPA 4KASA 2ZJQS 3S1RK 3PIPS 1I6VA 2FQTA 2VUMC 3GTLA 1IS1A 5JVHS 1VLOA 3CQZC 4BY7K 3GTPK 2XCOA 4WFAS 3S15C 1EI6A 1Y1VC 5IOTA 3HOXK 4AYBL 1VRQC 2ZFZA 4G7ZA 5IYCC 2JA8C 4KM8A 3S14K 1K83C 2NVXK 4C2MC 1WORA 2CFAB 5JVOA 2ZJPS 1B4BA 2NVYC 2L5NA 4YG2A 2E2IA 4C3IC 1BDFA 1X31C 2Y3PA 1J6VA 1PJ6A 2R7ZA 1VGXA 2VUMK 3AD8C 4QIWL 3A8KA 3CQZK 5CHPA 3FOFA 1WQFA 3HOWC 1Y1VK 1F7UA 2CFAA 3PO3C 5C44C 3LPXA 1XZQB 1O24A 5IYCK 4GTAA 2JA8K 1USMA 4QIWD 2R93C 1K83K 4MQ9A 4C2MK 3AD9C 1XXAA 2JA7C 4NOIA 1R9TC 2NVYK 3G4CA 3N0BA 2E2HA 1XXCA 4C3IK 5M3FK 4BXXC 2A6EA 1UV7A 4PAAA 5M5YK 1I50A 4WFBS 1WQGA 2NVTC 1FEUA 1TWCC 1XZQA 1PJ5A 1JOEA 4A3EC 1Y1WA 3HOWK 4A3KC 1WOPA 4BLBA 5M3MK 5C44K 3PO3K 3I4MC 3GTMA 2ZJRS 4A3LC 3AD7C 4X6AC 2R93K 4A3IC 3OPFA 5IYDC 3QX3A 4LR2A 3GTOC 2GSOA 1HQMA 2JA7K 2PMZL 1YX2A 2XCQA 1R9TK 2JA6A
chains in the Genus database with same CATH topology
4OIRA 1TWHK 2E2HC 1ZYRA 2E2IK 1TWFC 4AYBD 3PO2K 3S1NK 3HOZK 2R7ZK 2NVTK 3GTGK 1TWCK 3S1RK 2R92C 4A3BC 3S2HK 5M5XK 1I6VA 2JA5C 1TWFK 2VUMC 2PMZD 4A3EK 3CQZC 4BY7K 4A3KK 3GTPK 4YFNA 4Y7NC 2A69A 4XSZA 3FKIC 3S15C 4YFXA 4XSXA 1Y1VC 3HOXK 4AYBL 3RZOK 1TWGC 4KMUA 4OIPA 3RZDC 3S16C 2E2JK 3GTMC 4Y7NK 4A3LK 3S17C 1YNNA 4A93C 4LJZA 4G7ZA 4GZYA 5IYCC 5IP9C 2JA8C 4A3CC 2B63C 3S15K 4X6AK 5M5WK 4BBRC 1YNJA 5TMCA 4XLNA 5C3EK 2Y0SL 2A68A 5FLMK 2NVQK 3GTOK 1K83C 4JK1A 4BBSC 2BE5A 3S14K 5IYBK 2WAQD 2NVXK 4C2MC 1I3QC 4A3DC 1TWAK 2O5JA 4KN7A 4LLGA 3WODA 3HOVK 2NVYC 4YG2A 3HOYC 1I50C 2E2HK 2A6HA 2JA6C 2YU9C 4C3IC 1WCMC 4Q5SA 4C3HC 1BDFA 3K7AC 1I50K 2Y0SD 5C4XC 2WAQL 2R92K 2WB1D 4A3BK 1Y1WC 2JA5K 2VUMK 4QIWL 4XLPA 3S1MC 4A3MC 4YFKA 4BY1C 4OIQA 3CQZK 3S2DC 1SMYA 3GTLC 3HKZL 1Y1WK 2CW0A 3FKIK 3HOWC 1Y1VK 3H0GC 5FJ8K 4BY1K 1TWGK 4A3FC 3RZDK 3GTQC 3S16K 3GTMK 3GTKC 3PO3C 5C44C 2WB1L 3S17K 3M4OK 4A3CK 4A93K 5IYCK 5IP9K 2JA8K 1I6HC 2B63K 5IP7C 4A3JC 4BBRK 4Y52C 4QIWD 2O5IA 3H3VL 2R93C 5C4JC 4QJVB 3M3YC 1K83K 4BBSK 4MQ9A 3GTJC 4OINA 4C2MK 3HKZD 1I3QK 5IP7K 4A3DK 3HOUC 1IW7A 4MEXA 4NOIA 2JA7C 1R9TC 2NVYK 3HOYK 4G7OA 2JA6K 2YU9K 3I4NC 3M4OC 3S1QC 4C3IK 1WCMK 5M3FK 1TWHC 4C3HK 4BXXC 2A6EA 3K7AK 3H3VD 5M5YK 5C4XK 4A3GC 4OIOA 3PO2C 3S1NC 4G7HA 3HOZC 2PA8L 2R7ZC 3S1MK 4ZH4A 2NVTC 3GTGC 1TWCC 4C3JC 3S1RC 3S2HC 4A3MK 3HOVC 4BXXK 3DXJA 3S2DK 3GTLK 4LK1A 4KN4A 4A3GK 4A3EC 3HOWK 4BY7C 4QJVA 5D4DA 4A3KC 3GTPC 3H0GK 4C3JK 4A3FK 1SFOC 3GTQK 3GTKK 5M3MK 5C44K 3HOXC 3I4MC 3PO3K 3RZOC 1I6HK 4A3JK 2E2JC 4A3LC 4Y52K 2PA8D 1SFOK 4X6AC 3S1QK 4LK0A 5C4JK 3M3YK 2R93K 3I4MK 4A3IC 5IYDC 3EQLA 4Q4ZA 2PPBA 3GTJK 5C3EC 2NVQC 3S14C 5FLMC 3GTOC 3HOUK 5IYBC 1HQMA 2E2IC 2PMZL 2NVXC 1R9TK 2JA7K 4A3IK 1TWAC 4MEYA 5IYDK 3I4NK 1XPPA 5TMFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OIR A;  1TWH K;  2E2H C;  1ZYR A;  2E2I K;  1TWF C;  4AYB D;  3PO2 K;  3S1N K;  3HOZ K;  2R7Z K;  2NVT K;  3GTG K;  1TWC K;  3S1R K;  2R92 C;  4A3B C;  3S2H K;  5M5X K;  1I6V A;  2JA5 C;  1TWF K;  2VUM C;  2PMZ D;  4A3E K;  3CQZ C;  4BY7 K;  4A3K K;  3GTP K;  4YFN A;  4Y7N C;  2A69 A;  4XSZ A;  3FKI C;  3S15 C;  4YFX A;  4XSX A;  1Y1V C;  3HOX K;  4AYB L;  3RZO K;  1TWG C;  4KMU A;  4OIP A;  3RZD C;  3S16 C;  2E2J K;  3GTM C;  4Y7N K;  4A3L K;  3S17 C;  1YNN A;  4A93 C;  4LJZ A;  4G7Z A;  4GZY A;  5IYC C;  5IP9 C;  2JA8 C;  4A3C C;  2B63 C;  3S15 K;  4X6A K;  5M5W K;  4BBR C;  1YNJ A;  5TMC A;  4XLN A;  5C3E K;  2Y0S L;  2A68 A;  5FLM K;  2NVQ K;  3GTO K;  1K83 C;  4JK1 A;  4BBS C;  2BE5 A;  3S14 K;  5IYB K;  2WAQ D;  2NVX K;  4C2M C;  1I3Q C;  4A3D C;  1TWA K;  2O5J A;  4KN7 A;  4LLG A;  3WOD A;  3HOV K;  2NVY C;  4YG2 A;  3HOY C;  1I50 C;  2E2H K;  2A6H A;  2JA6 C;  2YU9 C;  4C3I C;  1WCM C;  4Q5S A;  4C3H C;  1BDF A;  3K7A C;  1I50 K;  2Y0S D;  5C4X C;  2WAQ L;  2R92 K;  2WB1 D;  4A3B K;  1Y1W C;  2JA5 K;  2VUM K;  4QIW L;  4XLP A;  3S1M C;  4A3M C;  4YFK A;  4BY1 C;  4OIQ A;  3CQZ K;  3S2D C;  1SMY A;  3GTL C;  3HKZ L;  1Y1W K;  2CW0 A;  3FKI K;  3HOW C;  1Y1V K;  3H0G C;  5FJ8 K;  4BY1 K;  1TWG K;  4A3F C;  3RZD K;  3GTQ C;  3S16 K;  3GTM K;  3GTK C;  3PO3 C;  5C44 C;  2WB1 L;  3S17 K;  3M4O K;  4A3C K;  4A93 K;  5IYC K;  5IP9 K;  2JA8 K;  1I6H C;  2B63 K;  5IP7 C;  4A3J C;  4BBR K;  4Y52 C;  4QIW D;  2O5I A;  3H3V L;  2R93 C;  5C4J C;  4QJV B;  3M3Y C;  1K83 K;  4BBS K;  4MQ9 A;  3GTJ C;  4OIN A;  4C2M K;  3HKZ D;  1I3Q K;  5IP7 K;  4A3D K;  3HOU C;  1IW7 A;  4MEX A;  4NOI A;  2JA7 C;  1R9T C;  2NVY K;  3HOY K;  4G7O A;  2JA6 K;  2YU9 K;  3I4N C;  3M4O C;  3S1Q C;  4C3I K;  1WCM K;  5M3F K;  1TWH C;  4C3H K;  4BXX C;  2A6E A;  3K7A K;  3H3V D;  5M5Y K;  5C4X K;  4A3G C;  4OIO A;  3PO2 C;  3S1N C;  4G7H A;  3HOZ C;  2PA8 L;  2R7Z C;  3S1M K;  4ZH4 A;  2NVT C;  3GTG C;  1TWC C;  4C3J C;  3S1R C;  3S2H C;  4A3M K;  3HOV C;  4BXX K;  3DXJ A;  3S2D K;  3GTL K;  4LK1 A;  4KN4 A;  4A3G K;  4A3E C;  3HOW K;  4BY7 C;  4QJV A;  5D4D A;  4A3K C;  3GTP C;  3H0G K;  4C3J K;  4A3F K;  1SFO C;  3GTQ K;  3GTK K;  5M3M K;  5C44 K;  3HOX C;  3I4M C;  3PO3 K;  3RZO C;  1I6H K;  4A3J K;  2E2J C;  4A3L C;  4Y52 K;  2PA8 D;  1SFO K;  4X6A C;  3S1Q K;  4LK0 A;  5C4J K;  3M3Y K;  2R93 K;  3I4M K;  4A3I C;  5IYD C;  3EQL A;  4Q4Z A;  2PPB A;  3GTJ K;  5C3E C;  2NVQ C;  3S14 C;  5FLM C;  3GTO C;  3HOU K;  5IYB C;  1HQM A;  2E2I C;  2PMZ L;  2NVX C;  1R9T K;  2JA7 K;  4A3I K;  1TWA C;  4MEY A;  5IYD K;  3I4N K;  1XPP A;  5TMF A; 
#chains in the Genus database with same CATH topology
 3AH5 A;  1ZYR A;  1V5V A;  2ZUE A;  2NVT K;  1BJT A;  1TWC K;  5IOS A;  5M5X K;  3G4A A;  2PMZ D;  4A3E K;  1O28 A;  3Q3Q A;  3A8J A;  4A3K K;  4YFN A;  3FKI C;  4KMA A;  4YFX A;  4XSX A;  3L4K A;  1EQR A;  4KMU A;  4BKW A;  2GAG C;  4A3L K;  4Y7N K;  4KMD A;  1YNN A;  4LJZ A;  4A3C C;  1DD5 A;  4DDQ A;  4X6A K;  2B63 C;  1SFO A;  4P5A A;  1L0W A;  4BBR C;  5M5W K;  1YNJ A;  3ORE A;  3GTO K;  4JK1 A;  2BE5 A;  2WAQ D;  1J6W A;  4WCE S;  3N3Y A;  4U67 S;  4WF9 S;  2O5J A;  4P5B A;  4GTD A;  3HOY C;  4GTC A;  1WQH A;  2YU9 C;  4Q5S A;  2P5M A;  3N0C A;  1XXB A;  2EBB A;  2WB1 D;  1WIH A;  3GTG A;  3T02 A;  4XLP A;  1YCL A;  1TWF A;  2PHC B;  3S2D C;  3GTL C;  4KMH A;  4P9S A;  2CW0 A;  3FKI K;  3H0G C;  5HL7 S;  3LYW A;  4A3C K;  4WIL A;  2B63 K;  4BBR K;  4Y52 C;  3H3V L;  5C4J C;  1J98 A;  3GTJ C;  4OIN A;  2V6U A;  3ADA C;  2KPU A;  4MEX A;  3HOY K;  1K83 A;  2YU9 K;  5E68 A;  1TWH C;  3H3V D;  2NVY A;  3S1N C;  2PA8 L;  2R7Z C;  4ZH4 A;  2JA5 A;  3BP3 A;  3S2H C;  3S2D K;  3GTL K;  4LK1 A;  4KN4 A;  1VH2 A;  4A3G K;  3GEH A;  3H0G K;  1IE0 A;  4C3J K;  1TWG A;  3RZO C;  2D6F C;  4WJ4 A;  4KAR A;  3AQO A;  4Y52 K;  2PA8 D;  5C4J K;  3GEE A;  3GTJ K;  1BS2 A;  5C3E C;  2NVQ C;  4J3N A;  5HL8 A;  2R93 A;  1TWA C;  1O2F B;  5EGE A;  3HOV C;  1TWH K;  2E2H C;  2E2I K;  3DLL S;  3PIO S;  2JA7 A;  4BLA A;  3S1N K;  1BGW A;  2R7Z K;  3S2H K;  2R92 C;  4A3B C;  1F93 A;  4GTF A;  4G0V A;  4Y7N C;  1TWC A;  1VJE A;  3RZO K;  3GTK A;  3T01 A;  3RZD C;  3GTM C;  4WJ3 M;  4A93 C;  4GZY A;  5TMC A;  5C3E K;  2NVQ K;  4GTL A;  2KXY A;  1I3Q C;  4A3D C;  1TWA K;  3GIR A;  4KB4 A;  3HOV K;  1JVI A;  2E2H K;  2A6H A;  2JA6 C;  1WCM C;  3K7A C;  1I50 K;  5C4X C;  2WAQ L;  3OEP A;  3FOE A;  2R92 K;  4A3B K;  3IPJ A;  3S1M C;  3TFJ A;  4A3M C;  4OIQ A;  1B4A A;  1SMY A;  1WSR A;  1IBA A;  2L3U A;  1Y1W K;  3GTP A;  1ZXO A;  1O26 A;  2ZUF A;  4BY1 K;  4A3F C;  3RZD K;  3GTQ C;  3GTM K;  2WB1 L;  4A93 K;  3FKI A;  4A3J C;  2O5I A;  1HI9 A;  4G0W A;  1G51 A;  1I3Q K;  5IP7 K;  4A3D K;  2NVX A;  3HOU C;  1ISE A;  2XCR B;  3A8I A;  4IO9 S;  3NUH A;  2GAH C;  4G7O A;  2JA6 K;  1J6X A;  1DCO A;  1WCM K;  3GEI A;  1O29 A;  1INN A;  3K7A K;  2V6S A;  5C4X K;  4A3G C;  3TTG A;  3HOZ C;  3S1M K;  4A3M K;  3GTG C;  4C3J C;  2VUM A;  1EK8 A;  2KWA A;  3DXJ A;  3MML B;  3CQZ A;  4G0U A;  4GTE A;  1Y1V A;  1PJ7 A;  5DM6 S;  2GSU A;  4A3F K;  3GTQ K;  2RH6 A;  3BP8 C;  4A3J K;  2E2J C;  3H0G A;  1SFO K;  4LK0 A;  4KC6 A;  3ERE D;  3EQL A;  2PPB A;  3SZY A;  5FLM C;  3HOU K;  5IYB C;  2E2I C;  4MEY A;  4KB2 A;  4FZB A;  1WOO A;  3GTJ A;  5TMF A;  5JFE A;  1O2A A;  5IOR A;  4AYB D;  5IOQ A;  4ILD A;  5EGH A;  3HOZ K;  1EH1 A;  3GTG K;  1TWH A;  3V4G A;  5JVG S;  2JA5 C;  1TWF K;  4KDD A;  3CF5 S;  1F7V A;  2JH3 A;  3CAG A;  1IL2 A;  3GSI A;  2A69 A;  4XSZ A;  3TFI A;  5HQH A;  4KM9 A;  1TWG C;  4OIP A;  3S16 C;  2FQO A;  2E2J K;  4GT9 A;  3S17 C;  3S15 K;  5IP9 C;  5TJ3 A;  1ZBS A;  4XLN A;  4AH6 A;  2Y0S L;  2A68 A;  5FLM K;  4BBS C;  5IYB K;  3GDZ A;  1R9T A;  1JQW A;  4M1X A;  4KN7 A;  4LLG A;  3LAJ A;  3WOD A;  1I50 C;  4FM9 A;  3HXA A;  2RGR A;  4LQY A;  1TWA A;  1C0A A;  4KAT A;  4C3H C;  2Y0S D;  1ZVU A;  1Y1W C;  2JA5 K;  4C45 A;  3L4J A;  4YFK A;  4BY1 C;  1O25 A;  3FHZ A;  4RMF A;  4XCH A;  3HKZ L;  2R92 A;  5FJ8 K;  1TWG K;  3S16 K;  3GTK C;  3S17 K;  5IP9 K;  1I6H C;  5IP7 C;  1WOS A;  1O27 A;  5CJ9 A;  2P8T A;  2V6T A;  3M3Y C;  1DCP A;  4QJV B;  4BBS K;  3GTO A;  3HKZ D;  5DM7 S;  2KQ1 A;  1GE9 A;  4GTB A;  1IW7 A;  1WSV A;  4GFQ A;  1RU0 A;  3S0X A;  3I4N C;  4IOC S;  3M4O C;  3S1Q C;  1I3Q A;  4C3H K;  2GSN A;  4OIO A;  3PO2 C;  4G7H A;  1XZP B;  1WCM A;  4BXX K;  3S1R C;  4LOW A;  1EFW A;  1O2B A;  5L46 A;  4BY7 C;  4QJV A;  5D4D A;  3GTP C;  4O2D A;  3VA7 A;  1USO A;  1SFO C;  3SZZ A;  3GTK K;  3HOX C;  1AB4 A;  3TFH A;  1I6H K;  2B63 A;  3M3Y K;  3I4M K;  2W7V A;  3GTQ A;  4Q4Z A;  4KAW X;  3S14 C;  4WFN S;  3T00 A;  1IQ0 A;  2NVX C;  4A3I K;  1XZP A;  1KQ4 A;  1F9N A;  3AQP A;  5IYD K;  3I4N K;  1XPP A;  4IOA S;  1ZQ1 C;  3M4O K;  3S1Q K;  2YU9 A;  4OIR A;  3JST A;  4PAB A;  3BUE A;  1TWF C;  1DCH A;  3PO2 K;  3LAP A;  4KAS A;  2ZJQ S;  3S1R K;  3PIP S;  1I6V A;  2FQT A;  2VUM C;  3GTL A;  1IS1 A;  5JVH S;  1VLO A;  3CQZ C;  4BY7 K;  3GTP K;  2XCO A;  4WFA S;  3S15 C;  1EI6 A;  1Y1V C;  5IOT A;  3HOX K;  4AYB L;  1VRQ C;  2ZFZ A;  4G7Z A;  5IYC C;  2JA8 C;  4KM8 A;  3S14 K;  1K83 C;  2NVX K;  4C2M C;  1WOR A;  2CFA B;  5JVO A;  2ZJP S;  1B4B A;  2NVY C;  2L5N A;  4YG2 A;  2E2I A;  4C3I C;  1BDF A;  1X31 C;  2Y3P A;  1J6V A;  1PJ6 A;  2R7Z A;  1VGX A;  2VUM K;  3AD8 C;  4QIW L;  3A8K A;  3CQZ K;  5CHP A;  3FOF A;  1WQF A;  3HOW C;  1Y1V K;  1F7U A;  2CFA A;  3PO3 C;  5C44 C;  3LPX A;  1XZQ B;  1O24 A;  5IYC K;  4GTA A;  2JA8 K;  1USM A;  4QIW D;  2R93 C;  1K83 K;  4MQ9 A;  4C2M K;  3AD9 C;  1XXA A;  2JA7 C;  4NOI A;  1R9T C;  2NVY K;  3G4C A;  3N0B A;  2E2H A;  1XXC A;  4C3I K;  5M3F K;  4BXX C;  2A6E A;  1UV7 A;  4PAA A;  5M5Y K;  1I50 A;  4WFB S;  1WQG A;  2NVT C;  1FEU A;  1TWC C;  1XZQ A;  1PJ5 A;  1JOE A;  4A3E C;  1Y1W A;  3HOW K;  4A3K C;  1WOP A;  4BLB A;  5M3M K;  5C44 K;  3PO3 K;  3I4M C;  3GTM A;  2ZJR S;  4A3L C;  3AD7 C;  4X6A C;  2R93 K;  4A3I C;  3OPF A;  5IYD C;  3QX3 A;  4LR2 A;  3GTO C;  2GSO A;  1HQM A;  2JA7 K;  2PMZ L;  1YX2 A;  2XCQ A;  1R9T K;  2JA6 A; 
#chains in the Genus database with same CATH homology
 4OIR A;  1TWH K;  2E2H C;  1ZYR A;  2E2I K;  1TWF C;  4AYB D;  3PO2 K;  3S1N K;  3HOZ K;  2R7Z K;  2NVT K;  3GTG K;  1TWC K;  3S1R K;  2R92 C;  4A3B C;  3S2H K;  5M5X K;  1I6V A;  2JA5 C;  1TWF K;  2VUM C;  2PMZ D;  4A3E K;  3CQZ C;  4BY7 K;  4A3K K;  3GTP K;  4YFN A;  4Y7N C;  2A69 A;  4XSZ A;  3FKI C;  3S15 C;  4YFX A;  4XSX A;  1Y1V C;  3HOX K;  4AYB L;  3RZO K;  1TWG C;  4KMU A;  4OIP A;  3RZD C;  3S16 C;  2E2J K;  3GTM C;  4Y7N K;  4A3L K;  3S17 C;  1YNN A;  4A93 C;  4LJZ A;  4G7Z A;  4GZY A;  5IYC C;  5IP9 C;  2JA8 C;  4A3C C;  2B63 C;  3S15 K;  4X6A K;  5M5W K;  4BBR C;  1YNJ A;  5TMC A;  4XLN A;  5C3E K;  2Y0S L;  2A68 A;  5FLM K;  2NVQ K;  3GTO K;  1K83 C;  4JK1 A;  4BBS C;  2BE5 A;  3S14 K;  5IYB K;  2WAQ D;  2NVX K;  4C2M C;  1I3Q C;  4A3D C;  1TWA K;  2O5J A;  4KN7 A;  4LLG A;  3WOD A;  3HOV K;  2NVY C;  4YG2 A;  3HOY C;  1I50 C;  2E2H K;  2A6H A;  2JA6 C;  2YU9 C;  4C3I C;  1WCM C;  4Q5S A;  4C3H C;  1BDF A;  3K7A C;  1I50 K;  2Y0S D;  5C4X C;  2WAQ L;  2R92 K;  2WB1 D;  4A3B K;  1Y1W C;  2JA5 K;  2VUM K;  4QIW L;  4XLP A;  3S1M C;  4A3M C;  4YFK A;  4BY1 C;  4OIQ A;  3CQZ K;  3S2D C;  1SMY A;  3GTL C;  3HKZ L;  1Y1W K;  2CW0 A;  3FKI K;  3HOW C;  1Y1V K;  3H0G C;  5FJ8 K;  4BY1 K;  1TWG K;  4A3F C;  3RZD K;  3GTQ C;  3S16 K;  3GTM K;  3GTK C;  3PO3 C;  5C44 C;  2WB1 L;  3S17 K;  3M4O K;  4A3C K;  4A93 K;  5IYC K;  5IP9 K;  2JA8 K;  1I6H C;  2B63 K;  5IP7 C;  4A3J C;  4BBR K;  4Y52 C;  4QIW D;  2O5I A;  3H3V L;  2R93 C;  5C4J C;  4QJV B;  3M3Y C;  1K83 K;  4BBS K;  4MQ9 A;  3GTJ C;  4OIN A;  4C2M K;  3HKZ D;  1I3Q K;  5IP7 K;  4A3D K;  3HOU C;  1IW7 A;  4MEX A;  4NOI A;  2JA7 C;  1R9T C;  2NVY K;  3HOY K;  4G7O A;  2JA6 K;  2YU9 K;  3I4N C;  3M4O C;  3S1Q C;  4C3I K;  1WCM K;  5M3F K;  1TWH C;  4C3H K;  4BXX C;  2A6E A;  3K7A K;  3H3V D;  5M5Y K;  5C4X K;  4A3G C;  4OIO A;  3PO2 C;  3S1N C;  4G7H A;  3HOZ C;  2PA8 L;  2R7Z C;  3S1M K;  4ZH4 A;  2NVT C;  3GTG C;  1TWC C;  4C3J C;  3S1R C;  3S2H C;  4A3M K;  3HOV C;  4BXX K;  3DXJ A;  3S2D K;  3GTL K;  4LK1 A;  4KN4 A;  4A3G K;  4A3E C;  3HOW K;  4BY7 C;  4QJV A;  5D4D A;  4A3K C;  3GTP C;  3H0G K;  4C3J K;  4A3F K;  1SFO C;  3GTQ K;  3GTK K;  5M3M K;  5C44 K;  3HOX C;  3I4M C;  3PO3 K;  3RZO C;  1I6H K;  4A3J K;  2E2J C;  4A3L C;  4Y52 K;  2PA8 D;  1SFO K;  4X6A C;  3S1Q K;  4LK0 A;  5C4J K;  3M3Y K;  2R93 K;  3I4M K;  4A3I C;  5IYD C;  3EQL A;  4Q4Z A;  2PPB A;  3GTJ K;  5C3E C;  2NVQ C;  3S14 C;  5FLM C;  3GTO C;  3HOU K;  5IYB C;  1HQM A;  2E2I C;  2PMZ L;  2NVX C;  1R9T K;  2JA7 K;  4A3I K;  1TWA C;  4MEY A;  5IYD K;  3I4N K;  1XPP A;  5TMF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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