2E2IC

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dgtp
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
total genus 48
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 2e2iC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 2e2iC01
1BDFA 4C3JK 5C3EK 1SMYA 2E2IK 2Y0SL 3I4MK 2O5JA 3HOXC 3M3YK 2PA8L 1YNNA 3DXJA 5TMFA 1TWHC 5FJ8K 2R92K 1Y1WK 5M5XK 5C4JK 3K7AC 4JK1A 4BBRC 2R93K 2WB1D 4A3DC 3S2DC 4Q4ZA 3HKZL 3GTLC 4ZH4A 2E2JC 2JA7K 2CW0A 3GTPK 4LK0A 4QJVB 4C3HK 1TWGK 3PO2C 3HOXK 5D4DA 2JA5C 4A3DK 3FKIC 1I50C 5IYDC 1TWHK 2Y0SD 3HOYC 3S1QC 3S16C 3S2HC 4NOIA 2PMZL 3K7AK 4A3CC 4Y7NC 3GTOC 2R7ZC 1ZYRA 3S1NC 4BBRK 4A3KC 2A69A 1SFOK 4LJZA 4XSXA 3GTLK 4KMUA 3HOWC 1IW7A 2NVQK 4QIWL 4A3EC 2YU9C 3PO2K 1TWCC 2JA5K 1R9TC 5IYDK 4AYBL 3RZDC 3S14K 4QJVA 1I3QC 3S16K 3S1QK 4A3CK 4XSZA 4A3MC 4Y7NK 3HOUK 2NVXC 2O5IA 3S1NK 3EQLA 2NVTC 2PMZD 4BBSC 3GTJC 4GZYA 4A3KK 1TWFK 3M4OC 3HOWK 3GTGC 3H0GC 4A3EK 2YU9K 2VUMC 2JA7C 4C2MC 4C3IC 4YG2A 4QIWD 3S15C 4YFKA 1R9TK 4A3BC 1I3QK 5FLMC 2BE5A 5IYBC 4XLPA 3S1MC 2NVXK 4AYBD 2B63C 4A3IC 3GTQC 2NVTK 4BXXC 3GTJK 1TWAC 4BBSK 4G7HA 5TMCA 1Y1VC 3M4OK 2NVYC 3GTKC 3GTGK 2A6EA 3HOVC 2E2JK 3H0GK 3S2DK 4YFNA 4Y52C 2VUMK 3S1RK 1I6HC 4KN4A 2JA6C 3PO3C 4BY7C 4A3GC 3S15K 4A3FC 1XPPA 4A3BK 4MEYA 5IYCC 4G7ZA 5C4XC 5FLMK 3FKIK 1I50K 5IYBK 3HOYK 1K83C 3S1MK 2B63K 3S2HK 3GTQK 5IP9C 4BXXK 4LLGA 1TWAK 3GTOK 2E2HC 2R7ZK 3I4NC 2JA8C 1Y1VK 2A68A 3HOZC 4X6AC 4Y52K 4Q5SA 5C3EC 1I6HK 4BY7K 3PO3K 3RZOC 4A3GK 4A93C 5M5WK 2WAQD 1TWCK 5M3FK 4MQ9A 4OIQA 3RZDK 1K83K 5IP9K 1WCMC 4OIOA 4A3MK 2E2HK 4LK1A 4KN7A 4OINA 2JA8K 3HOZK 5M5YK 4A3LC 4X6AK 1YNJA 4OIRA 5C44C 5IP7C 3WODA 4C3HC 1TWGC 2WAQL 3RZOK 3CQZC 4XLNA 4MEXA 4A93K 4C2MK 4C3IK 1I6VA 4BY1C 3H3VL 2PPBA 1WCMK 1SFOC 3GTMC 4A3IK 4A3LK 1HQMA 3S1RC 2NVQC 2NVYK 3S17C 4A3JC 5C44K 5IP7K 3GTKK 3HOVK 4YFXA 3CQZK 4OIPA 4C3JC 2E2IC 2JA6K 3I4MC 3M3YC 3S14C 4A3FK 4BY1K 2PA8D 5IYCK 5C4XK 5M3MK 3HOUC 2A6HA 2R92C 2WB1L 1Y1WC 5C4JC 3GTMK 3H3VD 1TWFC 2R93C 3I4NK 4A3JK 3S17K 3HKZD 3GTPC 4G7OA
chains in the Genus database with same CATH superfamily
4C3JK 2E2IK 3I4MK 2O5JA 3GTQA 5CHPA 3DXJA 1JQWA 1Y1VA 5M5XK 3K7AC 1EQRA 4BBRC 1VRQC 3OREA 3GTLC 1TWCA 2CW0A 2RH6A 1JVIA 3ERED 1XZQA 4QJVB 4C3HK 2Y3PA 3HOXK 3JSTA 5D4DA 3CF5S 2Y0SD 2ZJQS 3HOYC 3S16C 1USMA 1SFOK 2V6SA 4XSXA 3AQOA 1V5VA 1IW7A 2NVQK 4QIWL 4WFAS 1TWCC 1USOA 5IYDK 3S14K 4QJVA 1I3QC 4A3CK 4Y7NK 3HOUK 4GTDA 3S1NK 3EQLA 2NVTC 2PMZD 1X31C 5HL7S 2GSOA 2ZJPS 3HOWK 3GTGC 2YU9K 2V6UA 3GEEA 5JVOA 2BE5A 4A3IC 4BBSK 5TMCA 4A3DK 2E2JK 2VUMK 4Y52C 5DM7S 4KN4A 4KASA 4A3GC 4KB2A 4MEYA 3FKIK 1I50K 1PJ6A 4KATA 4PAAA 2B63K 1TWAK 4WCES 1ZBSA 3I4NC 4PABA 1TWGA 3CQZA 1TWHA 4Q5SA 5C3EC 1XZPB 3ADAC 4G0WA 3RZOC 1HI9A 4KC6A 1WQHA 5M3FK 3RZDK 5IP9K 4LK1A 1INNA 3SZYA 4A3LC 4X6AK 3N3YA 1YNJA 4OIRA 5C44C 5IP7C 2GAGC 3WODA 1TWGC 3CQZC 4XLNA 4C2MK 1DCPA 1XZPA 1WCMK 4P5BA 1WOSA 3FOFA 3S17C 4KARA 1KQ4A 5HL8A 2NVXA 4BKWA 4G0VA 2GAHC 5IYCK 4BLAA 2A6HA 3FOEA 5C4JC 3AD9C 4GTLA 3L4KA 2R93C 1J6WA 4A3JK 3GTPC 1EI6A 2PA8L 4J3NA 1YNNA 4G0UA 2R7ZA 1EFWA 2R92K 1Y1WK 2FQOA 2WB1D 1F93A 3S2DC 1O26A 4Q4ZA 1C0AA 4LK0A 3HXAA 3T02A 1K83A 3PO2C 2FQTA 2JA5C 3BP3A 2E2HA 1B4AA 1VH2A 3K7AK 2GSNA 4BBRK 2R7ZC 1ZYRA 1ISEA 4A3KC 2A69A 3GTLK 1YX2A 4KMUA 4IO9S 1R9TC 3GEHA 4AYBL 3S16K 1F7UA 4A3MC 2NVYA 3T01A 5IOTA 4GTBA 4GZYA 3GTJC 1TWFK 4IOCS 3M4OC 2JA6A 2ZFZA 3PIOS 4YG2A 3S15C 1VLOA 4YFKA 2ZUFA 1I3QK 3S1MC 3T00A 3A8JA 3GTQC 3LAJA 4BXXC 2NVTK 2E2IA 1Y1VC 2NVYC 3GTGK 2A6EA 3HOVC 4DDQA 1IBAA 2JA6C 3PO3C 1B4BA 4A3FC 1XPPA 4G7ZA 3S2HK 3GTOK 3HOZC 4LQYA 3G4CA 2JH3A 4Y52K 4ILDA 5IOQA 4A3GK 3GIRA 1DD5A 1SFOA 4OIQA 4OIOA 1JOEA 1VJEA 4C3HC 3N0BA 3RZOK 4C3IK 3DLLS 4BY1C 3H3VL 1BJTA 4KM8A 2ZJRS 3Q3QA 2JA7A 4GTCA 1SFOC 4A3LK 1HQMA 3S1RC 2NVQC 5C44K 5IP7K 3GTKK 4YFXA 3CQZK 3M3YC 3S14C 2PA8D 5C4XK 3HOUC 2VUMA 1WIHA 3GSIA 2ZUEA 3S17K 2JA7C 4G7OA 3FKIA 1J6VA 1BDFA 1I50A 2Y0SL 1TWAA 5TMFA 1XXAA 3AQPA 4KDDA 1TWHC 3GEIA 5FJ8K 3CAGA 5C4JK 4JK1A 1DCHA 3S0XA 2R93K 3OEPA 1BS2A 4A3DC 5E68A 3HKZL 4ZH4A 2E2JC 3GTPK 3LYWA 3AH5A 3VA7A 1IS1A 3FKIC 1I50C 3S1QC 2PMZL 1GE9A 3H0GA 4LJZA 2V6TA 4KM9A 1O2AA 1WSRA 4A3EC 3PO2K 3TFIA 4KB4A 2JA5K 4WFBS 2XCRB 3RZDC 1L0WA 1J6XA 2NVXC 4A3KK 1WQFA 2CFAB 1IL2A 3H0GC 2KXYA 5JVHS 4C2MC 1R9TK 4QIWD 4AH6A 4A3BC 4BLBA 5FLMC 2EBBA 5IYBC 4XLPA 2XCQA 3GTJK 4G7HA 3M4OK 5L46A 4YFNA 1I6HC 2CFAA 2R92A 4BY7C 1PJ5A 3S15K 1Y1WA 5IYCC 2XCOA 2KWAA 1RU0A 3TTGA 3HOYK 1K83C 3S1MK 4KAWX 3GTQK 4WF9S 1ZQ1C 4BXXK 2E2HC 2JA8C 1Y1VK 2A68A 4XCHA 4FZBA 1XXCA 4C45A 1ZVUA 3A8IA 3PO3K 4A93C 5M5WK 1TWCK 3GTMA 4MQ9A 1WORA 3HOZK 3TFJA 2P5MA 3AD7C 3TFHA 1BGWA 4P5AA 3GDZA 2WAQL 4MEXA 1O28A 4GTFA 1I6VA 1TWFA 2PPBA 1O2FB 3GTMC 4A3IK 4GTAA 4O2DA 3PIPS 4IOAS 5HQHA 1UV7A 1O24A 1I3QA 4OIPA 4C3JC 1O29A 2PHCB 2E2IC 3I4MC 1IQ0A 1O25A 2P8TA 4BY1K 3BUEA 3MMLB 2WB1L 4M1XA 3GTGA 4U67S 1WOPA 1TWFC 5CJ9A 3I4NK 5EGEA 3S1RK 3HKZD 1WQGA 5C3EK 3BP8C 1SMYA 3HOXC 1WSVA 3M3YK 3GTOA 4WILA 2YU9A 3IPJA 2JA7K 4GFQA 4RMFA 3L4JA 1TWGK 5IYDC 1TWHK 3S2HC 1J98A 4NOIA 3LAPA 4A3CC 4Y7NC 3GTOC 3S1NC 3SZZA 2GSUA 3HOWC 1ZXOA 2YU9C 1FEUA 1AB4A 3NUHA 2B63A 4KMHA 5IORA 1WOOA 3S1QK 4FM9A 4XSZA 3G4AA 4P9SA 3GTKA 2O5IA 4BBSC 2KQ1A 2RGRA 5JFEA 4A3EK 4KMDA 2VUMC 4C3IC 5IOSA 2D6FC 3QX3A 2NVXK 4AYBD 2B63C 5EGHA 1TWAC 5DM6S 4GT9A 5TJ3A 3S2DK 3GTKC 3H0GK 1PJ7A 1O2BA 4LOWA 4A3BK 5C4XC 1WCMA 5FLMK 2R93A 5IYBK 4WJ3M 2W7VA 3GTPA 3A8KA 5IP9C 4LLGA 4WFNS 1EK8A 2R7ZK 4X6AC 1I6HK 3OPFA 4BY7K 4GTEA 1EH1A 2WAQD 1DCOA 1K83K 1WCMC 4A3MK 4WJ4A 2E2HK 4OINA 4KN7A 2JA8K 1YCLA 5M5YK 2JA5A 3N0CA 3AD8C 1VGXA 4A93K 3V4GA 5JVGS 4LR2A 1XXBA 2KPUA 1R9TA 1F7VA 2NVYK 4A3JC 3HOVK 1G51A 2JA6K 3LPXA 4A3FK 1O27A 3GTJA 2L3UA 1F9NA 1IE0A 5M3MK 2R92C 3FHZA 1Y1WC 3GTLA 3GTMK 3H3VD 2L5NA 1XZQB 4KMAA
chains in the Genus database with same CATH topology
1BDFA 4C3JK 5C3EK 1SMYA 2E2IK 2Y0SL 3I4MK 2O5JA 3HOXC 3M3YK 2PA8L 1YNNA 3DXJA 5TMFA 1TWHC 5FJ8K 2R92K 1Y1WK 5M5XK 5C4JK 3K7AC 4JK1A 4BBRC 2R93K 2WB1D 4A3DC 3S2DC 4Q4ZA 3HKZL 3GTLC 4ZH4A 2E2JC 2JA7K 2CW0A 3GTPK 4LK0A 4QJVB 4C3HK 1TWGK 3PO2C 3HOXK 5D4DA 2JA5C 4A3DK 3FKIC 1I50C 5IYDC 1TWHK 2Y0SD 3HOYC 3S1QC 3S16C 3S2HC 4NOIA 2PMZL 3K7AK 4A3CC 4Y7NC 3GTOC 2R7ZC 1ZYRA 3S1NC 4BBRK 4A3KC 2A69A 1SFOK 4LJZA 4XSXA 3GTLK 4KMUA 3HOWC 1IW7A 2NVQK 4QIWL 4A3EC 2YU9C 3PO2K 1TWCC 2JA5K 1R9TC 5IYDK 4AYBL 3RZDC 3S14K 4QJVA 1I3QC 3S16K 3S1QK 4A3CK 4XSZA 4A3MC 4Y7NK 3HOUK 2NVXC 2O5IA 3S1NK 3EQLA 2NVTC 2PMZD 4BBSC 3GTJC 4GZYA 4A3KK 1TWFK 3M4OC 3HOWK 3GTGC 3H0GC 4A3EK 2YU9K 2VUMC 2JA7C 4C2MC 4C3IC 4YG2A 4QIWD 3S15C 4YFKA 1R9TK 4A3BC 1I3QK 5FLMC 2BE5A 5IYBC 4XLPA 3S1MC 2NVXK 4AYBD 2B63C 4A3IC 3GTQC 2NVTK 4BXXC 3GTJK 1TWAC 4BBSK 4G7HA 5TMCA 1Y1VC 3M4OK 2NVYC 3GTKC 3GTGK 2A6EA 3HOVC 2E2JK 3H0GK 3S2DK 4YFNA 4Y52C 2VUMK 3S1RK 1I6HC 4KN4A 2JA6C 3PO3C 4BY7C 4A3GC 3S15K 4A3FC 1XPPA 4A3BK 4MEYA 5IYCC 4G7ZA 5C4XC 5FLMK 3FKIK 1I50K 5IYBK 3HOYK 1K83C 3S1MK 2B63K 3S2HK 3GTQK 5IP9C 4BXXK 4LLGA 1TWAK 3GTOK 2E2HC 2R7ZK 3I4NC 2JA8C 1Y1VK 2A68A 3HOZC 4X6AC 4Y52K 4Q5SA 5C3EC 1I6HK 4BY7K 3PO3K 3RZOC 4A3GK 4A93C 5M5WK 2WAQD 1TWCK 5M3FK 4MQ9A 4OIQA 3RZDK 1K83K 5IP9K 1WCMC 4OIOA 4A3MK 2E2HK 4LK1A 4KN7A 4OINA 2JA8K 3HOZK 5M5YK 4A3LC 4X6AK 1YNJA 4OIRA 5C44C 5IP7C 3WODA 4C3HC 1TWGC 2WAQL 3RZOK 3CQZC 4XLNA 4MEXA 4A93K 4C2MK 4C3IK 1I6VA 4BY1C 3H3VL 2PPBA 1WCMK 1SFOC 3GTMC 4A3IK 4A3LK 1HQMA 3S1RC 2NVQC 2NVYK 3S17C 4A3JC 5C44K 5IP7K 3GTKK 3HOVK 4YFXA 3CQZK 4OIPA 4C3JC 2E2IC 2JA6K 3I4MC 3M3YC 3S14C 4A3FK 4BY1K 2PA8D 5IYCK 5C4XK 5M3MK 3HOUC 2A6HA 2R92C 2WB1L 1Y1WC 5C4JC 3GTMK 3H3VD 1TWFC 2R93C 3I4NK 4A3JK 3S17K 3HKZD 3GTPC 4G7OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BDF A;  4C3J K;  5C3E K;  1SMY A;  2E2I K;  2Y0S L;  3I4M K;  2O5J A;  3HOX C;  3M3Y K;  2PA8 L;  1YNN A;  3DXJ A;  5TMF A;  1TWH C;  5FJ8 K;  2R92 K;  1Y1W K;  5M5X K;  5C4J K;  3K7A C;  4JK1 A;  4BBR C;  2R93 K;  2WB1 D;  4A3D C;  3S2D C;  4Q4Z A;  3HKZ L;  3GTL C;  4ZH4 A;  2E2J C;  2JA7 K;  2CW0 A;  3GTP K;  4LK0 A;  4QJV B;  4C3H K;  1TWG K;  3PO2 C;  3HOX K;  5D4D A;  2JA5 C;  4A3D K;  3FKI C;  1I50 C;  5IYD C;  1TWH K;  2Y0S D;  3HOY C;  3S1Q C;  3S16 C;  3S2H C;  4NOI A;  2PMZ L;  3K7A K;  4A3C C;  4Y7N C;  3GTO C;  2R7Z C;  1ZYR A;  3S1N C;  4BBR K;  4A3K C;  2A69 A;  1SFO K;  4LJZ A;  4XSX A;  3GTL K;  4KMU A;  3HOW C;  1IW7 A;  2NVQ K;  4QIW L;  4A3E C;  2YU9 C;  3PO2 K;  1TWC C;  2JA5 K;  1R9T C;  5IYD K;  4AYB L;  3RZD C;  3S14 K;  4QJV A;  1I3Q C;  3S16 K;  3S1Q K;  4A3C K;  4XSZ A;  4A3M C;  4Y7N K;  3HOU K;  2NVX C;  2O5I A;  3S1N K;  3EQL A;  2NVT C;  2PMZ D;  4BBS C;  3GTJ C;  4GZY A;  4A3K K;  1TWF K;  3M4O C;  3HOW K;  3GTG C;  3H0G C;  4A3E K;  2YU9 K;  2VUM C;  2JA7 C;  4C2M C;  4C3I C;  4YG2 A;  4QIW D;  3S15 C;  4YFK A;  1R9T K;  4A3B C;  1I3Q K;  5FLM C;  2BE5 A;  5IYB C;  4XLP A;  3S1M C;  2NVX K;  4AYB D;  2B63 C;  4A3I C;  3GTQ C;  2NVT K;  4BXX C;  3GTJ K;  1TWA C;  4BBS K;  4G7H A;  5TMC A;  1Y1V C;  3M4O K;  2NVY C;  3GTK C;  3GTG K;  2A6E A;  3HOV C;  2E2J K;  3H0G K;  3S2D K;  4YFN A;  4Y52 C;  2VUM K;  3S1R K;  1I6H C;  4KN4 A;  2JA6 C;  3PO3 C;  4BY7 C;  4A3G C;  3S15 K;  4A3F C;  1XPP A;  4A3B K;  4MEY A;  5IYC C;  4G7Z A;  5C4X C;  5FLM K;  3FKI K;  1I50 K;  5IYB K;  3HOY K;  1K83 C;  3S1M K;  2B63 K;  3S2H K;  3GTQ K;  5IP9 C;  4BXX K;  4LLG A;  1TWA K;  3GTO K;  2E2H C;  2R7Z K;  3I4N C;  2JA8 C;  1Y1V K;  2A68 A;  3HOZ C;  4X6A C;  4Y52 K;  4Q5S A;  5C3E C;  1I6H K;  4BY7 K;  3PO3 K;  3RZO C;  4A3G K;  4A93 C;  5M5W K;  2WAQ D;  1TWC K;  5M3F K;  4MQ9 A;  4OIQ A;  3RZD K;  1K83 K;  5IP9 K;  1WCM C;  4OIO A;  4A3M K;  2E2H K;  4LK1 A;  4KN7 A;  4OIN A;  2JA8 K;  3HOZ K;  5M5Y K;  4A3L C;  4X6A K;  1YNJ A;  4OIR A;  5C44 C;  5IP7 C;  3WOD A;  4C3H C;  1TWG C;  2WAQ L;  3RZO K;  3CQZ C;  4XLN A;  4MEX A;  4A93 K;  4C2M K;  4C3I K;  1I6V A;  4BY1 C;  3H3V L;  2PPB A;  1WCM K;  1SFO C;  3GTM C;  4A3I K;  4A3L K;  1HQM A;  3S1R C;  2NVQ C;  2NVY K;  3S17 C;  4A3J C;  5C44 K;  5IP7 K;  3GTK K;  3HOV K;  4YFX A;  3CQZ K;  4OIP A;  4C3J C;  2E2I C;  2JA6 K;  3I4M C;  3M3Y C;  3S14 C;  4A3F K;  4BY1 K;  2PA8 D;  5IYC K;  5C4X K;  5M3M K;  3HOU C;  2A6H A;  2R92 C;  2WB1 L;  1Y1W C;  5C4J C;  3GTM K;  3H3V D;  1TWF C;  2R93 C;  3I4N K;  4A3J K;  3S17 K;  3HKZ D;  3GTP C;  4G7O A; 
#chains in the Genus database with same CATH topology
 4C3J K;  2E2I K;  3I4M K;  2O5J A;  3GTQ A;  5CHP A;  3DXJ A;  1JQW A;  1Y1V A;  5M5X K;  3K7A C;  1EQR A;  4BBR C;  1VRQ C;  3ORE A;  3GTL C;  1TWC A;  2CW0 A;  2RH6 A;  1JVI A;  3ERE D;  1XZQ A;  4QJV B;  4C3H K;  2Y3P A;  3HOX K;  3JST A;  5D4D A;  3CF5 S;  2Y0S D;  2ZJQ S;  3HOY C;  3S16 C;  1USM A;  1SFO K;  2V6S A;  4XSX A;  3AQO A;  1V5V A;  1IW7 A;  2NVQ K;  4QIW L;  4WFA S;  1TWC C;  1USO A;  5IYD K;  3S14 K;  4QJV A;  1I3Q C;  4A3C K;  4Y7N K;  3HOU K;  4GTD A;  3S1N K;  3EQL A;  2NVT C;  2PMZ D;  1X31 C;  5HL7 S;  2GSO A;  2ZJP S;  3HOW K;  3GTG C;  2YU9 K;  2V6U A;  3GEE A;  5JVO A;  2BE5 A;  4A3I C;  4BBS K;  5TMC A;  4A3D K;  2E2J K;  2VUM K;  4Y52 C;  5DM7 S;  4KN4 A;  4KAS A;  4A3G C;  4KB2 A;  4MEY A;  3FKI K;  1I50 K;  1PJ6 A;  4KAT A;  4PAA A;  2B63 K;  1TWA K;  4WCE S;  1ZBS A;  3I4N C;  4PAB A;  1TWG A;  3CQZ A;  1TWH A;  4Q5S A;  5C3E C;  1XZP B;  3ADA C;  4G0W A;  3RZO C;  1HI9 A;  4KC6 A;  1WQH A;  5M3F K;  3RZD K;  5IP9 K;  4LK1 A;  1INN A;  3SZY A;  4A3L C;  4X6A K;  3N3Y A;  1YNJ A;  4OIR A;  5C44 C;  5IP7 C;  2GAG C;  3WOD A;  1TWG C;  3CQZ C;  4XLN A;  4C2M K;  1DCP A;  1XZP A;  1WCM K;  4P5B A;  1WOS A;  3FOF A;  3S17 C;  4KAR A;  1KQ4 A;  5HL8 A;  2NVX A;  4BKW A;  4G0V A;  2GAH C;  5IYC K;  4BLA A;  2A6H A;  3FOE A;  5C4J C;  3AD9 C;  4GTL A;  3L4K A;  2R93 C;  1J6W A;  4A3J K;  3GTP C;  1EI6 A;  2PA8 L;  4J3N A;  1YNN A;  4G0U A;  2R7Z A;  1EFW A;  2R92 K;  1Y1W K;  2FQO A;  2WB1 D;  1F93 A;  3S2D C;  1O26 A;  4Q4Z A;  1C0A A;  4LK0 A;  3HXA A;  3T02 A;  1K83 A;  3PO2 C;  2FQT A;  2JA5 C;  3BP3 A;  2E2H A;  1B4A A;  1VH2 A;  3K7A K;  2GSN A;  4BBR K;  2R7Z C;  1ZYR A;  1ISE A;  4A3K C;  2A69 A;  3GTL K;  1YX2 A;  4KMU A;  4IO9 S;  1R9T C;  3GEH A;  4AYB L;  3S16 K;  1F7U A;  4A3M C;  2NVY A;  3T01 A;  5IOT A;  4GTB A;  4GZY A;  3GTJ C;  1TWF K;  4IOC S;  3M4O C;  2JA6 A;  2ZFZ A;  3PIO S;  4YG2 A;  3S15 C;  1VLO A;  4YFK A;  2ZUF A;  1I3Q K;  3S1M C;  3T00 A;  3A8J A;  3GTQ C;  3LAJ A;  4BXX C;  2NVT K;  2E2I A;  1Y1V C;  2NVY C;  3GTG K;  2A6E A;  3HOV C;  4DDQ A;  1IBA A;  2JA6 C;  3PO3 C;  1B4B A;  4A3F C;  1XPP A;  4G7Z A;  3S2H K;  3GTO K;  3HOZ C;  4LQY A;  3G4C A;  2JH3 A;  4Y52 K;  4ILD A;  5IOQ A;  4A3G K;  3GIR A;  1DD5 A;  1SFO A;  4OIQ A;  4OIO A;  1JOE A;  1VJE A;  4C3H C;  3N0B A;  3RZO K;  4C3I K;  3DLL S;  4BY1 C;  3H3V L;  1BJT A;  4KM8 A;  2ZJR S;  3Q3Q A;  2JA7 A;  4GTC A;  1SFO C;  4A3L K;  1HQM A;  3S1R C;  2NVQ C;  5C44 K;  5IP7 K;  3GTK K;  4YFX A;  3CQZ K;  3M3Y C;  3S14 C;  2PA8 D;  5C4X K;  3HOU C;  2VUM A;  1WIH A;  3GSI A;  2ZUE A;  3S17 K;  2JA7 C;  4G7O A;  3FKI A;  1J6V A;  1BDF A;  1I50 A;  2Y0S L;  1TWA A;  5TMF A;  1XXA A;  3AQP A;  4KDD A;  1TWH C;  3GEI A;  5FJ8 K;  3CAG A;  5C4J K;  4JK1 A;  1DCH A;  3S0X A;  2R93 K;  3OEP A;  1BS2 A;  4A3D C;  5E68 A;  3HKZ L;  4ZH4 A;  2E2J C;  3GTP K;  3LYW A;  3AH5 A;  3VA7 A;  1IS1 A;  3FKI C;  1I50 C;  3S1Q C;  2PMZ L;  1GE9 A;  3H0G A;  4LJZ A;  2V6T A;  4KM9 A;  1O2A A;  1WSR A;  4A3E C;  3PO2 K;  3TFI A;  4KB4 A;  2JA5 K;  4WFB S;  2XCR B;  3RZD C;  1L0W A;  1J6X A;  2NVX C;  4A3K K;  1WQF A;  2CFA B;  1IL2 A;  3H0G C;  2KXY A;  5JVH S;  4C2M C;  1R9T K;  4QIW D;  4AH6 A;  4A3B C;  4BLB A;  5FLM C;  2EBB A;  5IYB C;  4XLP A;  2XCQ A;  3GTJ K;  4G7H A;  3M4O K;  5L46 A;  4YFN A;  1I6H C;  2CFA A;  2R92 A;  4BY7 C;  1PJ5 A;  3S15 K;  1Y1W A;  5IYC C;  2XCO A;  2KWA A;  1RU0 A;  3TTG A;  3HOY K;  1K83 C;  3S1M K;  4KAW X;  3GTQ K;  4WF9 S;  1ZQ1 C;  4BXX K;  2E2H C;  2JA8 C;  1Y1V K;  2A68 A;  4XCH A;  4FZB A;  1XXC A;  4C45 A;  1ZVU A;  3A8I A;  3PO3 K;  4A93 C;  5M5W K;  1TWC K;  3GTM A;  4MQ9 A;  1WOR A;  3HOZ K;  3TFJ A;  2P5M A;  3AD7 C;  3TFH A;  1BGW A;  4P5A A;  3GDZ A;  2WAQ L;  4MEX A;  1O28 A;  4GTF A;  1I6V A;  1TWF A;  2PPB A;  1O2F B;  3GTM C;  4A3I K;  4GTA A;  4O2D A;  3PIP S;  4IOA S;  5HQH A;  1UV7 A;  1O24 A;  1I3Q A;  4OIP A;  4C3J C;  1O29 A;  2PHC B;  2E2I C;  3I4M C;  1IQ0 A;  1O25 A;  2P8T A;  4BY1 K;  3BUE A;  3MML B;  2WB1 L;  4M1X A;  3GTG A;  4U67 S;  1WOP A;  1TWF C;  5CJ9 A;  3I4N K;  5EGE A;  3S1R K;  3HKZ D;  1WQG A;  5C3E K;  3BP8 C;  1SMY A;  3HOX C;  1WSV A;  3M3Y K;  3GTO A;  4WIL A;  2YU9 A;  3IPJ A;  2JA7 K;  4GFQ A;  4RMF A;  3L4J A;  1TWG K;  5IYD C;  1TWH K;  3S2H C;  1J98 A;  4NOI A;  3LAP A;  4A3C C;  4Y7N C;  3GTO C;  3S1N C;  3SZZ A;  2GSU A;  3HOW C;  1ZXO A;  2YU9 C;  1FEU A;  1AB4 A;  3NUH A;  2B63 A;  4KMH A;  5IOR A;  1WOO A;  3S1Q K;  4FM9 A;  4XSZ A;  3G4A A;  4P9S A;  3GTK A;  2O5I A;  4BBS C;  2KQ1 A;  2RGR A;  5JFE A;  4A3E K;  4KMD A;  2VUM C;  4C3I C;  5IOS A;  2D6F C;  3QX3 A;  2NVX K;  4AYB D;  2B63 C;  5EGH A;  1TWA C;  5DM6 S;  4GT9 A;  5TJ3 A;  3S2D K;  3GTK C;  3H0G K;  1PJ7 A;  1O2B A;  4LOW A;  4A3B K;  5C4X C;  1WCM A;  5FLM K;  2R93 A;  5IYB K;  4WJ3 M;  2W7V A;  3GTP A;  3A8K A;  5IP9 C;  4LLG A;  4WFN S;  1EK8 A;  2R7Z K;  4X6A C;  1I6H K;  3OPF A;  4BY7 K;  4GTE A;  1EH1 A;  2WAQ D;  1DCO A;  1K83 K;  1WCM C;  4A3M K;  4WJ4 A;  2E2H K;  4OIN A;  4KN7 A;  2JA8 K;  1YCL A;  5M5Y K;  2JA5 A;  3N0C A;  3AD8 C;  1VGX A;  4A93 K;  3V4G A;  5JVG S;  4LR2 A;  1XXB A;  2KPU A;  1R9T A;  1F7V A;  2NVY K;  4A3J C;  3HOV K;  1G51 A;  2JA6 K;  3LPX A;  4A3F K;  1O27 A;  3GTJ A;  2L3U A;  1F9N A;  1IE0 A;  5M3M K;  2R92 C;  3FHZ A;  1Y1W C;  3GTL A;  3GTM K;  3H3V D;  2L5N A;  1XZQ B;  4KMA A; 
#chains in the Genus database with same CATH homology
 1BDF A;  4C3J K;  5C3E K;  1SMY A;  2E2I K;  2Y0S L;  3I4M K;  2O5J A;  3HOX C;  3M3Y K;  2PA8 L;  1YNN A;  3DXJ A;  5TMF A;  1TWH C;  5FJ8 K;  2R92 K;  1Y1W K;  5M5X K;  5C4J K;  3K7A C;  4JK1 A;  4BBR C;  2R93 K;  2WB1 D;  4A3D C;  3S2D C;  4Q4Z A;  3HKZ L;  3GTL C;  4ZH4 A;  2E2J C;  2JA7 K;  2CW0 A;  3GTP K;  4LK0 A;  4QJV B;  4C3H K;  1TWG K;  3PO2 C;  3HOX K;  5D4D A;  2JA5 C;  4A3D K;  3FKI C;  1I50 C;  5IYD C;  1TWH K;  2Y0S D;  3HOY C;  3S1Q C;  3S16 C;  3S2H C;  4NOI A;  2PMZ L;  3K7A K;  4A3C C;  4Y7N C;  3GTO C;  2R7Z C;  1ZYR A;  3S1N C;  4BBR K;  4A3K C;  2A69 A;  1SFO K;  4LJZ A;  4XSX A;  3GTL K;  4KMU A;  3HOW C;  1IW7 A;  2NVQ K;  4QIW L;  4A3E C;  2YU9 C;  3PO2 K;  1TWC C;  2JA5 K;  1R9T C;  5IYD K;  4AYB L;  3RZD C;  3S14 K;  4QJV A;  1I3Q C;  3S16 K;  3S1Q K;  4A3C K;  4XSZ A;  4A3M C;  4Y7N K;  3HOU K;  2NVX C;  2O5I A;  3S1N K;  3EQL A;  2NVT C;  2PMZ D;  4BBS C;  3GTJ C;  4GZY A;  4A3K K;  1TWF K;  3M4O C;  3HOW K;  3GTG C;  3H0G C;  4A3E K;  2YU9 K;  2VUM C;  2JA7 C;  4C2M C;  4C3I C;  4YG2 A;  4QIW D;  3S15 C;  4YFK A;  1R9T K;  4A3B C;  1I3Q K;  5FLM C;  2BE5 A;  5IYB C;  4XLP A;  3S1M C;  2NVX K;  4AYB D;  2B63 C;  4A3I C;  3GTQ C;  2NVT K;  4BXX C;  3GTJ K;  1TWA C;  4BBS K;  4G7H A;  5TMC A;  1Y1V C;  3M4O K;  2NVY C;  3GTK C;  3GTG K;  2A6E A;  3HOV C;  2E2J K;  3H0G K;  3S2D K;  4YFN A;  4Y52 C;  2VUM K;  3S1R K;  1I6H C;  4KN4 A;  2JA6 C;  3PO3 C;  4BY7 C;  4A3G C;  3S15 K;  4A3F C;  1XPP A;  4A3B K;  4MEY A;  5IYC C;  4G7Z A;  5C4X C;  5FLM K;  3FKI K;  1I50 K;  5IYB K;  3HOY K;  1K83 C;  3S1M K;  2B63 K;  3S2H K;  3GTQ K;  5IP9 C;  4BXX K;  4LLG A;  1TWA K;  3GTO K;  2E2H C;  2R7Z K;  3I4N C;  2JA8 C;  1Y1V K;  2A68 A;  3HOZ C;  4X6A C;  4Y52 K;  4Q5S A;  5C3E C;  1I6H K;  4BY7 K;  3PO3 K;  3RZO C;  4A3G K;  4A93 C;  5M5W K;  2WAQ D;  1TWC K;  5M3F K;  4MQ9 A;  4OIQ A;  3RZD K;  1K83 K;  5IP9 K;  1WCM C;  4OIO A;  4A3M K;  2E2H K;  4LK1 A;  4KN7 A;  4OIN A;  2JA8 K;  3HOZ K;  5M5Y K;  4A3L C;  4X6A K;  1YNJ A;  4OIR A;  5C44 C;  5IP7 C;  3WOD A;  4C3H C;  1TWG C;  2WAQ L;  3RZO K;  3CQZ C;  4XLN A;  4MEX A;  4A93 K;  4C2M K;  4C3I K;  1I6V A;  4BY1 C;  3H3V L;  2PPB A;  1WCM K;  1SFO C;  3GTM C;  4A3I K;  4A3L K;  1HQM A;  3S1R C;  2NVQ C;  2NVY K;  3S17 C;  4A3J C;  5C44 K;  5IP7 K;  3GTK K;  3HOV K;  4YFX A;  3CQZ K;  4OIP A;  4C3J C;  2E2I C;  2JA6 K;  3I4M C;  3M3Y C;  3S14 C;  4A3F K;  4BY1 K;  2PA8 D;  5IYC K;  5C4X K;  5M3M K;  3HOU C;  2A6H A;  2R92 C;  2WB1 L;  1Y1W C;  5C4J C;  3GTM K;  3H3V D;  1TWF C;  2R93 C;  3I4N K;  4A3J K;  3S17 K;  3HKZ D;  3GTP C;  4G7O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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