2E2IC

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dgtp
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 48
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 2e2iC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 2e2iC01
1BDFA 5IP9C 3CQZC 5C4JC 4G7ZA 4QIWD 4A3KK 3GTKK 4A3BC 4BBRC 2R93C 4BY7K 4KN7A 2NVTC 2PA8L 3HOYK 1I50C 5TMFA 3M4OC 2E2IK 3GTMC 1K83K 4A93K 3DXJA 3S2DK 1SMYA 4XLNA 3PO3K 2VUMK 2R7ZK 4LLGA 4MEYA 3S1NC 3GTPK 1I6VA 5IYCC 2NVQC 4A3DK 1Y1VC 2PMZD 3S1MC 2WAQL 4A3EK 4A3FK 4A3CK 4NOIA 4MEXA 5TMCA 4BY7C 1ZYRA 2WB1L 3H3VL 4KN4A 4YFNA 3M3YC 4A3JC 4G7OA 5IP7C 4A3MC 5IYBC 1YNNA 1TWFC 2JA5C 2PPBA 4BY1C 2E2JK 3HOUK 3S14K 1TWHC 5FLMK 1I6HK 1Y1WC 1WCMK 4BBRK 5C4XK 3PO2K 3FKIC 4AYBL 5C44C 4A3IK 3GTOK 2R93K 4C2MC 4C3IC 2JA8C 1TWGC 4YFKA 3EQLA 3RZDK 4Q5SA 2Y0SL 3GTPC 2R92K 5C4JK 3I4MC 4A3KC 2Y0SD 4A3GC 5D4DA 2E2HC 1I6HC 1Y1WK 3HKZD 1WCMC 2A68A 3HOYC 3PO2C 4ZH4A 3GTGC 3K7AC 5C4XC 2A6HA 4KMUA 1YNJA 1TWAK 2NVYK 3HKZL 3GTQK 2B63K 3GTMK 3HOZK 3M3YK 4MQ9A 3GTLC 4BXXK 4OIQA 4GZYA 5IP7K 3CQZK 5M5XK 2R92C 4OIRA 2PA8D 2NVXC 5C3EC 1TWAC 3HOXC 2JA7K 3GTGK 1TWGK 1HQMA 2R7ZC 2VUMC 4LK1A 3S1NK 1TWCC 4QIWL 4XSZA 5M5WK 5FLMC 1TWHK 3I4NK 5IYDC 4OIPA 4YFXA 3FKIK 4A3IC 4C2MK 4C3IK 3RZOC 2JA8K 5M5YK 4C3JC 1SFOC 3S1RC 4X6AC 2JA7C 3HOZC 5FJ8K 4G7HA 3S2HC 3HOUC 4A3MK 3GTLK 1TWFK 2JA5K 3H0GK 3S16C 4AYBD 2O5JA 3S17K 5M3FK 4Y52C 5IYDK 5C3EK 3S15C 4C3HK 2A6EA 2B63C 3GTJK 2JA6K 3HOWK 2CW0A 2O5IA 2NVTK 1I3QC 3HOXK 1TWCK 3I4MK 4LJZA 5IYCK 4A3GK 3S17C 2YU9K 4A3LK 4OIOA 1R9TC 4QJVA 2WAQD 3I4NC 2PMZL 4OINA 2NVXK 3K7AK 4JK1A 4XSXA 2E2IC 1I50K 4C3JK 1SFOK 4C3HC 3M4OK 4XLPA 4BXXC 4A3JK 3S1QC 1IW7A 3HOVK 3H0GC 3S16K 5IP9K 4Y7NK 2E2JC 2BE5A 3S14C 3S1MK 4A3CC 2YU9C 4A3LC 1R9TK 3RZOK 1XPPA 3GTOC 5C44K 3S1RK 4X6AK 3S2DC 4BBSK 3GTJC 2JA6C 3PO3C 3RZDC 1I3QK 3WODA 4A3DC 4Q4ZA 4A3EC 4A3FC 4Y7NC 3GTKC 1Y1VK 5IYBK 2WB1D 3H3VD 3S15K 2A69A 4A3BK 4Y52K 2E2HK 1K83C 4A93C 4LK0A 2NVYC 4YG2A 3HOWC 3GTQC 5M3MK 4QJVB 3S2HK 3S1QK 4BBSC 2NVQK 3HOVC 4BY1K
chains in the Genus database with same CATH superfamily
5C4JC 4KMHA 2JA6A 2PA8L 1I50C 1WSVA 3A8JA 3HXAA 1K83K 3S2DK 4LLGA 4MEYA 3S1NC 1I6VA 1Y1VC 2PMZD 4A3EK 4A3FK 4NOIA 5TMCA 4BY7C 1XZQA 3H3VL 3FHZA 4KN4A 4YFNA 1J98A 3VA7A 3HOUK 3DLLS 4KATA 5FLMK 3PIOS 3PO2K 1ZXOA 4AYBL 4A3IK 1HI9A 4C2MC 1EFWA 1Y1VA 2P5MA 1VH2A 3AD9C 2ZUFA 3I4MC 4WFNS 1I6HC 1VLOA 3HKZD 1WCMC 3PO2C 4ZH4A 3GTGC 3H0GA 2XCQA 3ADAC 1YNJA 2NVYK 3S15K 3PIPS 4P5AA 3GTLC 4GZYA 3S0XA 2ZJRS 5C3EC 5HL7S 3TFHA 1TWAC 2R7ZC 2VUMC 1F7VA 1AB4A 3S1NK 2B63A 1IBAA 5FLMC 3V4GA 1KQ4A 4WF9S 5IYDC 3A8IA 4LR2A 5JFEA 3HOUC 1TWFK 3H0GK 3S16C 3LPXA 2PHCB 1ZQ1C 3QX3A 3FOEA 3LYWA 4GTDA 5C3EK 3S15C 3CQZA 2B63C 3GTJK 5DM6S 1WQGA 1I3QC 2KQ1A 1INNA 3I4MK 1EH1A 4G0VA 4LJZA 3JSTA 5IYCK 3N0CA 2NVXK 2PMZL 1EQRA 1DD5A 4JK1A 5E68A 3TFIA 3H0GC 3S1MK 4A3LC 2XCRB 1R9TK 4X6AK 1JOEA 3A8KA 4GTAA 3GTKC 4GTFA 2L3UA 2E2HK 4WILA 1IQ0A 3LAPA 3S2HK 2NVYC 3HOWC 4O2DA 3S1QK 4BBSC 3AD8C 1RU0A 4G7ZA 4QIWD 4WJ4A 3G4CA 4KN7A 1O27A 1XXBA 4P9SA 3GTMC 1J6VA 2E2HA 3DXJA 4XLNA 3AD7C 3GTGA 5EGEA 5IYCC 2NVQC 1WIHA 4A3DK 3GTOA 4FM9A 1O25A 2L5NA 3CF5S 1ZYRA 2CFAB 5IP7C 4BBSK 2E2JK 3S14K 1TWHC 2JA5A 1Y1WC 1WCMK 4BBRK 2R93K 3GTQA 1UV7A 3GTKA 3GIRA 4LOWA 4IO9S 4GTLA 4A3GC 5D4DA 1Y1WK 3GTMK 3GTQK 3M3YK 4MQ9A 2JH3A 1WOOA 2GSUA 3CQZK 4KARA 4GTEA 4OIRA 2PA8D 1BJTA 3BUEA 2JA7K 3GTGK 1HQMA 4LK1A 5CJ9A 1VGXA 4G0WA 1I3QA 4OIPA 5DM7S 3FKIK 3RZOC 5M5YK 4X6AC 1PJ6A 2GAHC 4A3MK 2JA5K 3GTMA 4AYBD 2GSOA 1DCPA 4Y52C 4DDQA 4KDDA 2A6EA 1G51A 4A3GK 1O26A 1R9TC 2WAQD 3I4NC 3K7AK 1TWHA 4XSXA 1I50K 3HOVK 1FEUA 2ZJPS 2BE5A 2JA7A 4IOAS 3GTLA 1O2BA 3GTOC 1V5VA 3S2DC 1WOPA 3WODA 4Q4ZA 4Y7NC 2A69A 1K83A 1WORA 1O2AA 3GDZA 4PABA 2GAGC 4A93C 5HL8A 4LK0A 2NVXA 3MMLB 4BKWA 3HOVC 1BDFA 1BS2A 1IE0A 3CQZC 1VJEA 4A3KK 3GTKK 3Q3QA 4LQYA 4M1XA 4BY7K 2NVTC 3HOYK 5TMFA 3M4OC 2E2IK 1XXCA 1XZQB 2R92A 4A93K 3T00A 1XZPA 3PO3K 2VUMK 2R7ZK 2YU9A 3GTPK 5HQHA 3S1MC 2EBBA 3M3YC 4A3JC 2RGRA 1DCOA 1B4AA 2JA5C 2PPBA 4BY1C 2VUMA 2R7ZA 1TWFA 5C4XK 3GSIA 5C44C 2W7VA 1TWGC 2FQOA 2Y0SL 3GTPC 2R92K 3SZZA 5C4JK 2Y0SD 2A68A 1TWAK 3HKZL 2B63K 4U67S 1YCLA 1J6WA 4OIQA 4GFQA 5M5XK 1XXAA 4WFBS 1ISEA 4C45A 1TWGK 1R9TA 4KM8A 1TWCC 5M5WK 2GSNA 3LAJA 3I4NK 4KASA 4YFXA 2XCOA 2KPUA 3TFJA 4GTBA 4C2MK 1SFOC 3SZYA 2JA7C 5FJ8K 4G7HA 3S2HC 4PAAA 1YX2A 5IYDK 2D6FC 3HOWK 4KB2A 2CW0A 2O5IA 3NUHA 5JVGS 1TWGA 4IOCS 1TWAA 3S17C 4A3LK 3FOFA 4QJVA 1X31C 3GEHA 3OEPA 4P5BA 2KXYA 4AH6A 4C3HC 4C3JK 5L46A 4A3JK 2FQTA 4KB4A 5IP9K 4Y7NK 3S14C 4A3CC 3GTPA 1IS1A 3AH5A 3RZOK 5C44K 3S1RK 2R93A 3GTJC 3PO3C 1F9NA 4WCES 4A3BK 1PJ7A 3H3VD 3IPJA 4GTCA 2V6UA 2ZJQS 1XZPB 1TWCA 2CFAA 1L0WA 1Y1WA 4RMFA 4YG2A 5M3MK 3GTQC 4QJVB 5IYBK 4BY1K 5IP9C 4J3NA 4A3BC 4BBRC 5JVHS 2R93C 1USOA 3GTJA 5IOQA 4BLBA 1SMYA 2P8TA 4KC6A 2WAQL 4A3CK 5TJ3A 4MEXA 1EK8A 2WB1L 4FZBA 4KMAA 4G7OA 1O28A 2KWAA 4A3MC 5IYBC 1YNNA 1TWFC 3G4AA 1VRQC 1I6HK 3FKIC 3GTOK 4C3IC 2JA8C 4YFKA 4WFAS 3N3YA 3T01A 3EQLA 1C0AA 3RZDK 4Q5SA 4BLAA 3N0BA 4A3KC 2E2HC 5IOSA 2NVQK 5C4XC 3HOYC 3HOXK 4KAWX 2NVTK 3K7AC 2A6HA 4KMUA 3T02A 3HOZK 1ZBSA 2V6SA 2RH6A 4BXXK 5IP7K 3FKIA 2R92C 1BGWA 3TTGA 1O29A 2NVXC 1USMA 1PJ5A 3HOXC 1J6XA 5EGHA 4QIWL 4XSZA 5CHPA 3L4KA 1TWHK 1ZVUA 2ZUEA 4A3IC 4C3IK 2JA8K 4C3JC 3S1RC 1WOSA 3HOZC 2Y3PA 1GE9A 3GTLK 3BP8C 1WCMA 2O5JA 3S17K 1IL2A 5M3FK 5JVOA 4WJ3M 1SFOA 1F93A 1WQFA 1WQHA 4KM9A 4C3HK 2JA6K 3ERED 2E2IA 1TWCK 5IORA 2YU9K 4OIOA 1JVIA 4OINA 1O2FB 3L4JA 3BP3A 1F7UA 2E2IC 3M4OK 1WSRA 3OPFA 1SFOK 2ZFZA 4XLPA 4BXXC 3S1QC 1IW7A 1B4BA 2V6TA 3S16K 2E2JC 3OREA 3AQOA 4KMDA 2YU9C 4ILDA 1XPPA 4G0UA 2JA6C 1DCHA 1I50A 3RZDC 1I3QK 4A3DC 3GEIA 3CAGA 1Y1VK 4A3EC 4A3FC 1EI6A 2WB1D 5IOTA 4Y52K 1O24A 4XCHA 1K83C 4GT9A 3AQPA 1JQWA 3GEEA 2NVYA
chains in the Genus database with same CATH topology
1BDFA 5IP9C 3CQZC 5C4JC 4G7ZA 4QIWD 4A3KK 3GTKK 4A3BC 4BBRC 2R93C 4BY7K 4KN7A 2NVTC 2PA8L 3HOYK 1I50C 5TMFA 3M4OC 2E2IK 3GTMC 1K83K 4A93K 3DXJA 3S2DK 1SMYA 4XLNA 3PO3K 2VUMK 2R7ZK 4LLGA 4MEYA 3S1NC 3GTPK 1I6VA 5IYCC 2NVQC 4A3DK 1Y1VC 2PMZD 3S1MC 2WAQL 4A3EK 4A3FK 4A3CK 4NOIA 4MEXA 5TMCA 4BY7C 1ZYRA 2WB1L 3H3VL 4KN4A 4YFNA 3M3YC 4A3JC 4G7OA 5IP7C 4A3MC 5IYBC 1YNNA 1TWFC 2JA5C 2PPBA 4BY1C 2E2JK 3HOUK 3S14K 1TWHC 5FLMK 1I6HK 1Y1WC 1WCMK 4BBRK 5C4XK 3PO2K 3FKIC 4AYBL 5C44C 4A3IK 3GTOK 2R93K 4C2MC 4C3IC 2JA8C 1TWGC 4YFKA 3EQLA 3RZDK 4Q5SA 2Y0SL 3GTPC 2R92K 5C4JK 3I4MC 4A3KC 2Y0SD 4A3GC 5D4DA 2E2HC 1I6HC 1Y1WK 3HKZD 1WCMC 2A68A 3HOYC 3PO2C 4ZH4A 3GTGC 3K7AC 5C4XC 2A6HA 4KMUA 1YNJA 1TWAK 2NVYK 3HKZL 3GTQK 2B63K 3GTMK 3HOZK 3M3YK 4MQ9A 3GTLC 4BXXK 4OIQA 4GZYA 5IP7K 3CQZK 5M5XK 2R92C 4OIRA 2PA8D 2NVXC 5C3EC 1TWAC 3HOXC 2JA7K 3GTGK 1TWGK 1HQMA 2R7ZC 2VUMC 4LK1A 3S1NK 1TWCC 4QIWL 4XSZA 5M5WK 5FLMC 1TWHK 3I4NK 5IYDC 4OIPA 4YFXA 3FKIK 4A3IC 4C2MK 4C3IK 3RZOC 2JA8K 5M5YK 4C3JC 1SFOC 3S1RC 4X6AC 2JA7C 3HOZC 5FJ8K 4G7HA 3S2HC 3HOUC 4A3MK 3GTLK 1TWFK 2JA5K 3H0GK 3S16C 4AYBD 2O5JA 3S17K 5M3FK 4Y52C 5IYDK 5C3EK 3S15C 4C3HK 2A6EA 2B63C 3GTJK 2JA6K 3HOWK 2CW0A 2O5IA 2NVTK 1I3QC 3HOXK 1TWCK 3I4MK 4LJZA 5IYCK 4A3GK 3S17C 2YU9K 4A3LK 4OIOA 1R9TC 4QJVA 2WAQD 3I4NC 2PMZL 4OINA 2NVXK 3K7AK 4JK1A 4XSXA 2E2IC 1I50K 4C3JK 1SFOK 4C3HC 3M4OK 4XLPA 4BXXC 4A3JK 3S1QC 1IW7A 3HOVK 3H0GC 3S16K 5IP9K 4Y7NK 2E2JC 2BE5A 3S14C 3S1MK 4A3CC 2YU9C 4A3LC 1R9TK 3RZOK 1XPPA 3GTOC 5C44K 3S1RK 4X6AK 3S2DC 4BBSK 3GTJC 2JA6C 3PO3C 3RZDC 1I3QK 3WODA 4A3DC 4Q4ZA 4A3EC 4A3FC 4Y7NC 3GTKC 1Y1VK 5IYBK 2WB1D 3H3VD 3S15K 2A69A 4A3BK 4Y52K 2E2HK 1K83C 4A93C 4LK0A 2NVYC 4YG2A 3HOWC 3GTQC 5M3MK 4QJVB 3S2HK 3S1QK 4BBSC 2NVQK 3HOVC 4BY1K
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BDF A;  5IP9 C;  3CQZ C;  5C4J C;  4G7Z A;  4QIW D;  4A3K K;  3GTK K;  4A3B C;  4BBR C;  2R93 C;  4BY7 K;  4KN7 A;  2NVT C;  2PA8 L;  3HOY K;  1I50 C;  5TMF A;  3M4O C;  2E2I K;  3GTM C;  1K83 K;  4A93 K;  3DXJ A;  3S2D K;  1SMY A;  4XLN A;  3PO3 K;  2VUM K;  2R7Z K;  4LLG A;  4MEY A;  3S1N C;  3GTP K;  1I6V A;  5IYC C;  2NVQ C;  4A3D K;  1Y1V C;  2PMZ D;  3S1M C;  2WAQ L;  4A3E K;  4A3F K;  4A3C K;  4NOI A;  4MEX A;  5TMC A;  4BY7 C;  1ZYR A;  2WB1 L;  3H3V L;  4KN4 A;  4YFN A;  3M3Y C;  4A3J C;  4G7O A;  5IP7 C;  4A3M C;  5IYB C;  1YNN A;  1TWF C;  2JA5 C;  2PPB A;  4BY1 C;  2E2J K;  3HOU K;  3S14 K;  1TWH C;  5FLM K;  1I6H K;  1Y1W C;  1WCM K;  4BBR K;  5C4X K;  3PO2 K;  3FKI C;  4AYB L;  5C44 C;  4A3I K;  3GTO K;  2R93 K;  4C2M C;  4C3I C;  2JA8 C;  1TWG C;  4YFK A;  3EQL A;  3RZD K;  4Q5S A;  2Y0S L;  3GTP C;  2R92 K;  5C4J K;  3I4M C;  4A3K C;  2Y0S D;  4A3G C;  5D4D A;  2E2H C;  1I6H C;  1Y1W K;  3HKZ D;  1WCM C;  2A68 A;  3HOY C;  3PO2 C;  4ZH4 A;  3GTG C;  3K7A C;  5C4X C;  2A6H A;  4KMU A;  1YNJ A;  1TWA K;  2NVY K;  3HKZ L;  3GTQ K;  2B63 K;  3GTM K;  3HOZ K;  3M3Y K;  4MQ9 A;  3GTL C;  4BXX K;  4OIQ A;  4GZY A;  5IP7 K;  3CQZ K;  5M5X K;  2R92 C;  4OIR A;  2PA8 D;  2NVX C;  5C3E C;  1TWA C;  3HOX C;  2JA7 K;  3GTG K;  1TWG K;  1HQM A;  2R7Z C;  2VUM C;  4LK1 A;  3S1N K;  1TWC C;  4QIW L;  4XSZ A;  5M5W K;  5FLM C;  1TWH K;  3I4N K;  5IYD C;  4OIP A;  4YFX A;  3FKI K;  4A3I C;  4C2M K;  4C3I K;  3RZO C;  2JA8 K;  5M5Y K;  4C3J C;  1SFO C;  3S1R C;  4X6A C;  2JA7 C;  3HOZ C;  5FJ8 K;  4G7H A;  3S2H C;  3HOU C;  4A3M K;  3GTL K;  1TWF K;  2JA5 K;  3H0G K;  3S16 C;  4AYB D;  2O5J A;  3S17 K;  5M3F K;  4Y52 C;  5IYD K;  5C3E K;  3S15 C;  4C3H K;  2A6E A;  2B63 C;  3GTJ K;  2JA6 K;  3HOW K;  2CW0 A;  2O5I A;  2NVT K;  1I3Q C;  3HOX K;  1TWC K;  3I4M K;  4LJZ A;  5IYC K;  4A3G K;  3S17 C;  2YU9 K;  4A3L K;  4OIO A;  1R9T C;  4QJV A;  2WAQ D;  3I4N C;  2PMZ L;  4OIN A;  2NVX K;  3K7A K;  4JK1 A;  4XSX A;  2E2I C;  1I50 K;  4C3J K;  1SFO K;  4C3H C;  3M4O K;  4XLP A;  4BXX C;  4A3J K;  3S1Q C;  1IW7 A;  3HOV K;  3H0G C;  3S16 K;  5IP9 K;  4Y7N K;  2E2J C;  2BE5 A;  3S14 C;  3S1M K;  4A3C C;  2YU9 C;  4A3L C;  1R9T K;  3RZO K;  1XPP A;  3GTO C;  5C44 K;  3S1R K;  4X6A K;  3S2D C;  4BBS K;  3GTJ C;  2JA6 C;  3PO3 C;  3RZD C;  1I3Q K;  3WOD A;  4A3D C;  4Q4Z A;  4A3E C;  4A3F C;  4Y7N C;  3GTK C;  1Y1V K;  5IYB K;  2WB1 D;  3H3V D;  3S15 K;  2A69 A;  4A3B K;  4Y52 K;  2E2H K;  1K83 C;  4A93 C;  4LK0 A;  2NVY C;  4YG2 A;  3HOW C;  3GTQ C;  5M3M K;  4QJV B;  3S2H K;  3S1Q K;  4BBS C;  2NVQ K;  3HOV C;  4BY1 K; 
#chains in the Genus database with same CATH topology
 5C4J C;  4KMH A;  2JA6 A;  2PA8 L;  1I50 C;  1WSV A;  3A8J A;  3HXA A;  1K83 K;  3S2D K;  4LLG A;  4MEY A;  3S1N C;  1I6V A;  1Y1V C;  2PMZ D;  4A3E K;  4A3F K;  4NOI A;  5TMC A;  4BY7 C;  1XZQ A;  3H3V L;  3FHZ A;  4KN4 A;  4YFN A;  1J98 A;  3VA7 A;  3HOU K;  3DLL S;  4KAT A;  5FLM K;  3PIO S;  3PO2 K;  1ZXO A;  4AYB L;  4A3I K;  1HI9 A;  4C2M C;  1EFW A;  1Y1V A;  2P5M A;  1VH2 A;  3AD9 C;  2ZUF A;  3I4M C;  4WFN S;  1I6H C;  1VLO A;  3HKZ D;  1WCM C;  3PO2 C;  4ZH4 A;  3GTG C;  3H0G A;  2XCQ A;  3ADA C;  1YNJ A;  2NVY K;  3S15 K;  3PIP S;  4P5A A;  3GTL C;  4GZY A;  3S0X A;  2ZJR S;  5C3E C;  5HL7 S;  3TFH A;  1TWA C;  2R7Z C;  2VUM C;  1F7V A;  1AB4 A;  3S1N K;  2B63 A;  1IBA A;  5FLM C;  3V4G A;  1KQ4 A;  4WF9 S;  5IYD C;  3A8I A;  4LR2 A;  5JFE A;  3HOU C;  1TWF K;  3H0G K;  3S16 C;  3LPX A;  2PHC B;  1ZQ1 C;  3QX3 A;  3FOE A;  3LYW A;  4GTD A;  5C3E K;  3S15 C;  3CQZ A;  2B63 C;  3GTJ K;  5DM6 S;  1WQG A;  1I3Q C;  2KQ1 A;  1INN A;  3I4M K;  1EH1 A;  4G0V A;  4LJZ A;  3JST A;  5IYC K;  3N0C A;  2NVX K;  2PMZ L;  1EQR A;  1DD5 A;  4JK1 A;  5E68 A;  3TFI A;  3H0G C;  3S1M K;  4A3L C;  2XCR B;  1R9T K;  4X6A K;  1JOE A;  3A8K A;  4GTA A;  3GTK C;  4GTF A;  2L3U A;  2E2H K;  4WIL A;  1IQ0 A;  3LAP A;  3S2H K;  2NVY C;  3HOW C;  4O2D A;  3S1Q K;  4BBS C;  3AD8 C;  1RU0 A;  4G7Z A;  4QIW D;  4WJ4 A;  3G4C A;  4KN7 A;  1O27 A;  1XXB A;  4P9S A;  3GTM C;  1J6V A;  2E2H A;  3DXJ A;  4XLN A;  3AD7 C;  3GTG A;  5EGE A;  5IYC C;  2NVQ C;  1WIH A;  4A3D K;  3GTO A;  4FM9 A;  1O25 A;  2L5N A;  3CF5 S;  1ZYR A;  2CFA B;  5IP7 C;  4BBS K;  2E2J K;  3S14 K;  1TWH C;  2JA5 A;  1Y1W C;  1WCM K;  4BBR K;  2R93 K;  3GTQ A;  1UV7 A;  3GTK A;  3GIR A;  4LOW A;  4IO9 S;  4GTL A;  4A3G C;  5D4D A;  1Y1W K;  3GTM K;  3GTQ K;  3M3Y K;  4MQ9 A;  2JH3 A;  1WOO A;  2GSU A;  3CQZ K;  4KAR A;  4GTE A;  4OIR A;  2PA8 D;  1BJT A;  3BUE A;  2JA7 K;  3GTG K;  1HQM A;  4LK1 A;  5CJ9 A;  1VGX A;  4G0W A;  1I3Q A;  4OIP A;  5DM7 S;  3FKI K;  3RZO C;  5M5Y K;  4X6A C;  1PJ6 A;  2GAH C;  4A3M K;  2JA5 K;  3GTM A;  4AYB D;  2GSO A;  1DCP A;  4Y52 C;  4DDQ A;  4KDD A;  2A6E A;  1G51 A;  4A3G K;  1O26 A;  1R9T C;  2WAQ D;  3I4N C;  3K7A K;  1TWH A;  4XSX A;  1I50 K;  3HOV K;  1FEU A;  2ZJP S;  2BE5 A;  2JA7 A;  4IOA S;  3GTL A;  1O2B A;  3GTO C;  1V5V A;  3S2D C;  1WOP A;  3WOD A;  4Q4Z A;  4Y7N C;  2A69 A;  1K83 A;  1WOR A;  1O2A A;  3GDZ A;  4PAB A;  2GAG C;  4A93 C;  5HL8 A;  4LK0 A;  2NVX A;  3MML B;  4BKW A;  3HOV C;  1BDF A;  1BS2 A;  1IE0 A;  3CQZ C;  1VJE A;  4A3K K;  3GTK K;  3Q3Q A;  4LQY A;  4M1X A;  4BY7 K;  2NVT C;  3HOY K;  5TMF A;  3M4O C;  2E2I K;  1XXC A;  1XZQ B;  2R92 A;  4A93 K;  3T00 A;  1XZP A;  3PO3 K;  2VUM K;  2R7Z K;  2YU9 A;  3GTP K;  5HQH A;  3S1M C;  2EBB A;  3M3Y C;  4A3J C;  2RGR A;  1DCO A;  1B4A A;  2JA5 C;  2PPB A;  4BY1 C;  2VUM A;  2R7Z A;  1TWF A;  5C4X K;  3GSI A;  5C44 C;  2W7V A;  1TWG C;  2FQO A;  2Y0S L;  3GTP C;  2R92 K;  3SZZ A;  5C4J K;  2Y0S D;  2A68 A;  1TWA K;  3HKZ L;  2B63 K;  4U67 S;  1YCL A;  1J6W A;  4OIQ A;  4GFQ A;  5M5X K;  1XXA A;  4WFB S;  1ISE A;  4C45 A;  1TWG K;  1R9T A;  4KM8 A;  1TWC C;  5M5W K;  2GSN A;  3LAJ A;  3I4N K;  4KAS A;  4YFX A;  2XCO A;  2KPU A;  3TFJ A;  4GTB A;  4C2M K;  1SFO C;  3SZY A;  2JA7 C;  5FJ8 K;  4G7H A;  3S2H C;  4PAA A;  1YX2 A;  5IYD K;  2D6F C;  3HOW K;  4KB2 A;  2CW0 A;  2O5I A;  3NUH A;  5JVG S;  1TWG A;  4IOC S;  1TWA A;  3S17 C;  4A3L K;  3FOF A;  4QJV A;  1X31 C;  3GEH A;  3OEP A;  4P5B A;  2KXY A;  4AH6 A;  4C3H C;  4C3J K;  5L46 A;  4A3J K;  2FQT A;  4KB4 A;  5IP9 K;  4Y7N K;  3S14 C;  4A3C C;  3GTP A;  1IS1 A;  3AH5 A;  3RZO K;  5C44 K;  3S1R K;  2R93 A;  3GTJ C;  3PO3 C;  1F9N A;  4WCE S;  4A3B K;  1PJ7 A;  3H3V D;  3IPJ A;  4GTC A;  2V6U A;  2ZJQ S;  1XZP B;  1TWC A;  2CFA A;  1L0W A;  1Y1W A;  4RMF A;  4YG2 A;  5M3M K;  3GTQ C;  4QJV B;  5IYB K;  4BY1 K;  5IP9 C;  4J3N A;  4A3B C;  4BBR C;  5JVH S;  2R93 C;  1USO A;  3GTJ A;  5IOQ A;  4BLB A;  1SMY A;  2P8T A;  4KC6 A;  2WAQ L;  4A3C K;  5TJ3 A;  4MEX A;  1EK8 A;  2WB1 L;  4FZB A;  4KMA A;  4G7O A;  1O28 A;  2KWA A;  4A3M C;  5IYB C;  1YNN A;  1TWF C;  3G4A A;  1VRQ C;  1I6H K;  3FKI C;  3GTO K;  4C3I C;  2JA8 C;  4YFK A;  4WFA S;  3N3Y A;  3T01 A;  3EQL A;  1C0A A;  3RZD K;  4Q5S A;  4BLA A;  3N0B A;  4A3K C;  2E2H C;  5IOS A;  2NVQ K;  5C4X C;  3HOY C;  3HOX K;  4KAW X;  2NVT K;  3K7A C;  2A6H A;  4KMU A;  3T02 A;  3HOZ K;  1ZBS A;  2V6S A;  2RH6 A;  4BXX K;  5IP7 K;  3FKI A;  2R92 C;  1BGW A;  3TTG A;  1O29 A;  2NVX C;  1USM A;  1PJ5 A;  3HOX C;  1J6X A;  5EGH A;  4QIW L;  4XSZ A;  5CHP A;  3L4K A;  1TWH K;  1ZVU A;  2ZUE A;  4A3I C;  4C3I K;  2JA8 K;  4C3J C;  3S1R C;  1WOS A;  3HOZ C;  2Y3P A;  1GE9 A;  3GTL K;  3BP8 C;  1WCM A;  2O5J A;  3S17 K;  1IL2 A;  5M3F K;  5JVO A;  4WJ3 M;  1SFO A;  1F93 A;  1WQF A;  1WQH A;  4KM9 A;  4C3H K;  2JA6 K;  3ERE D;  2E2I A;  1TWC K;  5IOR A;  2YU9 K;  4OIO A;  1JVI A;  4OIN A;  1O2F B;  3L4J A;  3BP3 A;  1F7U A;  2E2I C;  3M4O K;  1WSR A;  3OPF A;  1SFO K;  2ZFZ A;  4XLP A;  4BXX C;  3S1Q C;  1IW7 A;  1B4B A;  2V6T A;  3S16 K;  2E2J C;  3ORE A;  3AQO A;  4KMD A;  2YU9 C;  4ILD A;  1XPP A;  4G0U A;  2JA6 C;  1DCH A;  1I50 A;  3RZD C;  1I3Q K;  4A3D C;  3GEI A;  3CAG A;  1Y1V K;  4A3E C;  4A3F C;  1EI6 A;  2WB1 D;  5IOT A;  4Y52 K;  1O24 A;  4XCH A;  1K83 C;  4GT9 A;  3AQP A;  1JQW A;  3GEE A;  2NVY A; 
#chains in the Genus database with same CATH homology
 1BDF A;  5IP9 C;  3CQZ C;  5C4J C;  4G7Z A;  4QIW D;  4A3K K;  3GTK K;  4A3B C;  4BBR C;  2R93 C;  4BY7 K;  4KN7 A;  2NVT C;  2PA8 L;  3HOY K;  1I50 C;  5TMF A;  3M4O C;  2E2I K;  3GTM C;  1K83 K;  4A93 K;  3DXJ A;  3S2D K;  1SMY A;  4XLN A;  3PO3 K;  2VUM K;  2R7Z K;  4LLG A;  4MEY A;  3S1N C;  3GTP K;  1I6V A;  5IYC C;  2NVQ C;  4A3D K;  1Y1V C;  2PMZ D;  3S1M C;  2WAQ L;  4A3E K;  4A3F K;  4A3C K;  4NOI A;  4MEX A;  5TMC A;  4BY7 C;  1ZYR A;  2WB1 L;  3H3V L;  4KN4 A;  4YFN A;  3M3Y C;  4A3J C;  4G7O A;  5IP7 C;  4A3M C;  5IYB C;  1YNN A;  1TWF C;  2JA5 C;  2PPB A;  4BY1 C;  2E2J K;  3HOU K;  3S14 K;  1TWH C;  5FLM K;  1I6H K;  1Y1W C;  1WCM K;  4BBR K;  5C4X K;  3PO2 K;  3FKI C;  4AYB L;  5C44 C;  4A3I K;  3GTO K;  2R93 K;  4C2M C;  4C3I C;  2JA8 C;  1TWG C;  4YFK A;  3EQL A;  3RZD K;  4Q5S A;  2Y0S L;  3GTP C;  2R92 K;  5C4J K;  3I4M C;  4A3K C;  2Y0S D;  4A3G C;  5D4D A;  2E2H C;  1I6H C;  1Y1W K;  3HKZ D;  1WCM C;  2A68 A;  3HOY C;  3PO2 C;  4ZH4 A;  3GTG C;  3K7A C;  5C4X C;  2A6H A;  4KMU A;  1YNJ A;  1TWA K;  2NVY K;  3HKZ L;  3GTQ K;  2B63 K;  3GTM K;  3HOZ K;  3M3Y K;  4MQ9 A;  3GTL C;  4BXX K;  4OIQ A;  4GZY A;  5IP7 K;  3CQZ K;  5M5X K;  2R92 C;  4OIR A;  2PA8 D;  2NVX C;  5C3E C;  1TWA C;  3HOX C;  2JA7 K;  3GTG K;  1TWG K;  1HQM A;  2R7Z C;  2VUM C;  4LK1 A;  3S1N K;  1TWC C;  4QIW L;  4XSZ A;  5M5W K;  5FLM C;  1TWH K;  3I4N K;  5IYD C;  4OIP A;  4YFX A;  3FKI K;  4A3I C;  4C2M K;  4C3I K;  3RZO C;  2JA8 K;  5M5Y K;  4C3J C;  1SFO C;  3S1R C;  4X6A C;  2JA7 C;  3HOZ C;  5FJ8 K;  4G7H A;  3S2H C;  3HOU C;  4A3M K;  3GTL K;  1TWF K;  2JA5 K;  3H0G K;  3S16 C;  4AYB D;  2O5J A;  3S17 K;  5M3F K;  4Y52 C;  5IYD K;  5C3E K;  3S15 C;  4C3H K;  2A6E A;  2B63 C;  3GTJ K;  2JA6 K;  3HOW K;  2CW0 A;  2O5I A;  2NVT K;  1I3Q C;  3HOX K;  1TWC K;  3I4M K;  4LJZ A;  5IYC K;  4A3G K;  3S17 C;  2YU9 K;  4A3L K;  4OIO A;  1R9T C;  4QJV A;  2WAQ D;  3I4N C;  2PMZ L;  4OIN A;  2NVX K;  3K7A K;  4JK1 A;  4XSX A;  2E2I C;  1I50 K;  4C3J K;  1SFO K;  4C3H C;  3M4O K;  4XLP A;  4BXX C;  4A3J K;  3S1Q C;  1IW7 A;  3HOV K;  3H0G C;  3S16 K;  5IP9 K;  4Y7N K;  2E2J C;  2BE5 A;  3S14 C;  3S1M K;  4A3C C;  2YU9 C;  4A3L C;  1R9T K;  3RZO K;  1XPP A;  3GTO C;  5C44 K;  3S1R K;  4X6A K;  3S2D C;  4BBS K;  3GTJ C;  2JA6 C;  3PO3 C;  3RZD C;  1I3Q K;  3WOD A;  4A3D C;  4Q4Z A;  4A3E C;  4A3F C;  4Y7N C;  3GTK C;  1Y1V K;  5IYB K;  2WB1 D;  3H3V D;  3S15 K;  2A69 A;  4A3B K;  4Y52 K;  2E2H K;  1K83 C;  4A93 C;  4LK0 A;  2NVY C;  4YG2 A;  3HOW C;  3GTQ C;  5M3M K;  4QJV B;  3S2H K;  3S1Q K;  4BBS C;  2NVQ K;  3HOV C;  4BY1 K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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