1TWHC

Rna polymerase ii complexed with 2'datp
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
266
structure length
266
Chain Sequence
EEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHRLGLIPLQSMDIEQLEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVDQVVVRGIDTLQKKVASILLALTQMDQD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase II largest subunit
publication title Structural basis of transcription: nucleotide selection by rotation in the RNA polymerase II active center.
pubmed doi rcsb
molecule tags Transcription
total genus 57
structure length 266
sequence length 266
ec nomenclature
pdb deposition date 2004-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 1twhC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 1twhC01
4C3IK 3S1QK 3PO3C 4Y7NK 2R7ZK 5IP9K 2JA7C 5D4DA 2E2HK 4QIWD 3GTQK 2E2JC 3HOYC 4A3BC 1TWAC 2NVQC 3WODA 2YU9K 3M3YK 3PO2K 4A3DC 4GZYA 3H0GK 4KN4A 3GTJC 4OIPA 5IP7K 1TWCC 2E2IK 2BE5A 5TMCA 4BBSK 4A3LC 1Y1VC 2Y0SL 5C3EK 3RZOK 2PPBA 3CQZK 1R9TC 4MEXA 4XLPA 4OINA 3S14C 2WB1L 1I6VA 3I4MK 5FLMC 3S1MK 2NVXC 2Y0SD 4A3GC 1YNJA 3S1RK 1WCMK 4C3IC 3S1QC 3HOZK 2WB1D 3HOVC 4Y7NC 4ZH4A 1I3QK 1TWFK 5IYCK 3HOWK 4LJZA 4Q4ZA 2PMZL 3S16K 3S17K 3GTQC 1ZYRA 2NVYK 4G7HA 4KN7A 3HKZL 3I4NC 5TMFA 5C4JK 4A93K 4C3JC 4A3MC 4X6AC 3M3YC 2R93C 4JK1A 1YNNA 1TWHC 3HOUK 4G7ZA 2PMZD 2NVTC 3HOXK 3HKZD 4YFNA 4BBSC 5C3EC 3RZOC 3CQZC 4BY7K 3GTPK 4A3IC 1SFOC 2VUMC 3I4MC 3RZDC 3GTGC 4C2MK 2JA5K 1HQMA 3FKIC 1TWGK 5C4XK 3S2HK 5IYBK 3S1RC 4Y52C 4AYBL 4BY1K 4XLNA 2B63C 3S16C 4MEYA 1I3QC 3S1NK 1Y1WK 3GTKK 4A3KK 2JA6K 1K83K 2R92K 3K7AK 3GTOC 3EQLA 4XSZA 3DXJA 4AYBD 4A3EK 3HOUC 4BXXK 4BBRK 2PA8L 2R7ZC 4QJVB 5IP9C 1SFOK 2WAQL 2A68A 3HOXC 2E2HC 3GTMK 4YG2A 2A69A 1SMYA 1BDFA 3S15K 3M4OK 4A3JK 2YU9C 3GTLK 4KMUA 3PO2C 3S2DK 3H0GC 4XSXA 4BY7C 3PO3K 2WAQD 4OIRA 5IP7C 2JA7K 4C2MC 2E2IC 1TWGC 2A6HA 3S17C 4MQ9A 4A3DK 3S1MC 3S1NC 1Y1WC 3GTKC 3GTJK 1K83C 4LK0A 2O5JA 4LK1A 1I6HK 4A3LK 1WCMC 3HOZC 4YFXA 4BXXC 4Q5SA 4BBRC 1R9TK 1TWFC 3S14K 4QJVA 5IYCC 3HOWC 4A3CK 5M3MK 3M4OC 4A3FK 5FJ8K 2NVYC 1I50K 5C4JC 4A93C 2NVXK 5IYDK 3GTLC 3S2DC 5M5XK 4G7OA 3HOVK 5C44K 2CW0A 1IW7A 5M5WK 2JA8K 2O5IA 3I4NK 4C3JK 4C3HK 4A3MK 2PA8D 1XPPA 2R93K 3GTPC 4X6AK 1TWHK 5M5YK 4OIOA 2NVTK 2JA5C 4NOIA 5C4XC 2E2JK 3S2HC 3HOYK 5IYBC 1I6HC 1TWAK 2NVQK 4A3BK 4BY1C 4A3CC 3H3VL 4A3IK 4A3FC 4A3KC 2JA6C 2R92C 4LLGA 1TWCK 3K7AC 1I50C 4YFKA 3FKIK 3RZDK 5IYDC 2VUMK 3GTGK 1Y1VK 4A3EC 4Y52K 5M3FK 3H3VD 3GTMC 5C44C 2B63K 3S15C 4OIQA 5FLMK 2JA8C 4QIWL 4A3JC 3GTOK 2A6EA 4A3GK 4C3HC
chains in the Genus database with same CATH superfamily
3G4CA 2NVXA 2GAGC 2R7ZK 3N3YA 5IP9K 1C0AA 2KQ1A 4KM9A 2E2HK 4QIWD 3GTQK 2E2JC 3TFHA 3HOYC 3M3YK 4KB2A 4A3DC 3H0GK 2D6FC 5IP7K 4BLAA 2BE5A 2E2IK 5TMCA 1TWHA 4A3LC 1F7UA 3RZOK 4XLPA 4OINA 2P8TA 3S1MK 5FLMC 2FQTA 3CQZA 2Y0SD 2L5NA 1YNJA 4GT9A 5IYCK 4M1XA 1WSVA 1I3QA 4C3JC 4A3MC 2R93C 1YNNA 2ZJQS 3ADAC 3HKZD 4KAWX 2R7ZA 4KATA 2E2HA 4A3IC 2XCQA 1UV7A 3GTGC 5C4XK 3H0GA 1TWGK 5IYBK 2EBBA 2E2IA 2B63C 3GEHA 3CF5S 3LPXA 3S1NK 4GFQA 3GTKK 1K83K 2XCOA 3K7AK 3DXJA 1USMA 2V6TA 3GDZA 3FOEA 3M4OK 1ISEA 4P5AA 1BJTA 1XXCA 1L0WA 3PO2C 3S2DK 2KPUA 3GIRA 3N0BA 4FM9A 3PO3K 4OIRA 4WCES 2JA7K 5JVGS 2A6HA 2ZFZA 3JSTA 3GTJK 1IS1A 1WCMC 4YFXA 1TWFC 3A8JA 5M3MK 4A3FK 1DCHA 5CHPA 1XZQB 1XXBA 3GTLC 1ZBSA 5HQHA 4G7OA 3HOVK 2ZUFA 2FQOA 2O5IA 5HL7S 1EFWA 1O2BA 3V4GA 3CAGA 3S2HC 1B4AA 4A3BK 2NVQK 3OEPA 1TWCK 2XCRB 3FKIK 5IYDC 1O24A 3GTJA 3GSIA 5M3FK 3H3VD 5C44C 3S15C 1Y1VA 3FOFA 4WILA 4A3JC 4WJ3M 4C3IK 3S1QK 4G0VA 1O29A 5DM7S 4G0WA 4ILDA 1TWAC 2YU9K 3WODA 4GZYA 1WIHA 3FHZA 4KN4A 4OIPA 5EGHA 2ZJPS 3BP8C 3CQZK 4GTEA 3S14C 2WB1L 5TJ3A 1XZQA 5EGEA 1J6VA 4A3GC 3HOZK 3FKIA 3S16K 1JVIA 1I3QK 3HOWK 2PMZL 1YX2A 3GTQC 5HL8A 5C4JK 4KN7A 4A93K 5TMFA 1TWFA 1WQHA 3M3YC 3N0CA 4JK1A 3PIPS 3HOUK 1PJ5A 2NVTC 3HOXK 1JQWA 2P5MA 4YFNA 4P5BA 3RZOC 4AH6A 2YU9A 2VUMC 2JA5K 2L3UA 4KDDA 5JFEA 4Y52C 4AYBL 4A3KK 2R92K 1BS2A 4XSZA 4A3EK 1Y1WA 4BXXK 4BBRK 4RMFA 1SMYA 1BDFA 2CFAB 3ERED 1O2FB 3HXAA 4IOAS 5L46A 5JVOA 4XSXA 2JH3A 1TWGC 4PAAA 3S17C 4MQ9A 5IOQA 3DLLS 1WQFA 4A3DK 3L4KA 3S1NC 3GTKC 1XZPB 3Q3QA 1K83C 4LK1A 4A3LK 4IOCS 2JA5A 2ZJRS 4GTFA 4A3CK 1USOA 3BP3A 3M4OC 5FJ8K 2NVYC 3S2DC 2R92A 1I50A 1YCLA 2CW0A 4WF9S 1EQRA 1EK8A 3TFIA 3AQPA 4C3JK 4C3HK 4A3MK 2PA8D 3AH5A 2R93K 3GTPC 4BKWA 1F9NA 2KWAA 4FZBA 4BY1C 2KXYA 4A3IK 4A3FC 2JA6C 2GSOA 3GTGK 3A8IA 1PJ6A 1Y1VK 3GTMC 2B63K 5E68A 1EI6A 1ZVUA 4DDQA 2CFAA 4GTCA 4Y7NK 5D4DA 2PHCB 4A3BC 2NVQC 3TFJA 3PO2K 1TWCC 1XZPA 2R93A 4BBSK 1ZQ1C 5C3EK 2PPBA 1R9TC 3LYWA 1O26A 1I6VA 3I4MK 2NVXC 1O27A 3LAPA 3S1RK 1WCMK 4C3IC 3S1QC 3GTGA 2WB1D 1TWFK 4LJZA 4G7HA 2B63A 3I4NC 1O28A 4X6AC 1X31C 1TWHC 4G7ZA 2PMZD 4LQYA 4LOWA 2ZUEA 3CQZC 1WOSA 4BY7K 1SFOC 3RZDC 3TTGA 4C2MK 1HQMA 3GTPA 3S0XA 3S2HK 5IOSA 3IPJA 3S16C 3VA7A 1I3QC 1Y1WK 1VGXA 3GTOC 4AYBD 2GSUA 3HOUC 1DCOA 3OPFA 2R7ZC 5IP9C 2WAQL 3HOXC 2E2HC 3S15K 1WCMA 1VH2A 4A3JK 4KMUA 3H0GC 4BLBA 5IP7C 1HI9A 3GTLA 2E2IC 3AD8C 1J6XA 3LAJA 1WQGA 3S1MC 1I6HK 4XCHA 4BXXC 4BBRC 3BUEA 3S14K 4QJVA 5IYCC 1WOPA 1RU0A 5DM6S 1WOOA 4P9SA 1I50K 1F7VA 1IE0A 5M5WK 4G0UA 2JA8K 4KMAA 1V5VA 3T01A 1XPPA 3OREA 4WFBS 4GTAA 4LR2A 5M5YK 4OIOA 1JOEA 2NVTK 1ZXOA 5C4XC 2E2JK 3HOYK 5IYBC 2GSNA 4A3CC 1TWAA 2VUMK 3K7AC 4WJ4A 1WSRA 1EH1A 1FEUA 1IQ0A 1O2AA 1SFOA 4Y52K 3SZZA 5FLMK 4QIWL 2A6EA 4KC6A 4C3HC 4WFAS 1GE9A 3PO3C 3GTOA 2JA7C 3A8KA 4KM8A 3GTQA 2Y3PA 3GTJC 1WORA 2Y0SL 1Y1VC 3S17K 4MEXA 1INNA 3L4JA 4KMHA 2VUMA 3HOVC 4Y7NC 4ZH4A 4Q4ZA 1ZYRA 2NVYK 3HKZL 1DD5A 1F93A 4KB4A 5CJ9A 4O2DA 4U67S 4BBSC 4WFNS 5C3EC 1BGWA 3GTPK 4KARA 3I4MC 3FKIC 3S1RC 3QX3A 4BY1K 4XLNA 1TWGA 4MEYA 4KASA 2JA6K 3EQLA 1VLOA 4J3NA 3T02A 3AD9C 3GTKA 1G51A 1K83A 2PA8L 4QJVB 3GTMK 2A68A 3SZYA 4YG2A 2A69A 3GEIA 2YU9C 3GTLK 4IO9S 4BY7C 2NVYA 4GTBA 2WAQD 4C2MC 4GTLA 5IOTA 2V6UA 2JA7A 3AD7C 3G4AA 1Y1WC 5JVHS 4LK0A 2O5JA 5IORA 3HOZC 3MMLB 1J98A 4Q5SA 1R9TK 3HOWC 2NVXK 4C45A 5C4JC 4A93C 5IYDK 1O25A 1IL2A 2JA6A 1PJ7A 5M5XK 2GAHC 5C44K 4PABA 1VRQC 1IW7A 1XXAA 3GTMA 3PIOS 3I4NK 1VJEA 4X6AK 1KQ4A 1TWHK 4GTDA 4KMDA 2JA5C 4NOIA 2V6SA 3T00A 1I6HC 1AB4A 1TWAK 3AQOA 3H3VL 1DCPA 2W7VA 3NUHA 4A3KC 2R92C 1SFOK 4LLGA 3RZDK 1I50C 4YFKA 1B4BA 1IBAA 1J6WA 4A3EC 1TWCA 4OIQA 2RH6A 2JA8C 1R9TA 2RGRA 3GTOK 3GEEA 4A3GK
chains in the Genus database with same CATH topology
4C3IK 3S1QK 3PO3C 4Y7NK 2R7ZK 5IP9K 2JA7C 5D4DA 2E2HK 4QIWD 3GTQK 2E2JC 3HOYC 4A3BC 1TWAC 2NVQC 3WODA 2YU9K 3M3YK 3PO2K 4A3DC 4GZYA 3H0GK 4KN4A 3GTJC 4OIPA 5IP7K 1TWCC 2E2IK 2BE5A 5TMCA 4BBSK 4A3LC 1Y1VC 2Y0SL 5C3EK 3RZOK 2PPBA 3CQZK 1R9TC 4MEXA 4XLPA 4OINA 3S14C 2WB1L 1I6VA 3I4MK 5FLMC 3S1MK 2NVXC 2Y0SD 4A3GC 1YNJA 3S1RK 1WCMK 4C3IC 3S1QC 3HOZK 2WB1D 3HOVC 4Y7NC 4ZH4A 1I3QK 1TWFK 5IYCK 3HOWK 4LJZA 4Q4ZA 2PMZL 3S16K 3S17K 3GTQC 1ZYRA 2NVYK 4G7HA 4KN7A 3HKZL 3I4NC 5TMFA 5C4JK 4A93K 4C3JC 4A3MC 4X6AC 3M3YC 2R93C 4JK1A 1YNNA 1TWHC 3HOUK 4G7ZA 2PMZD 2NVTC 3HOXK 3HKZD 4YFNA 4BBSC 5C3EC 3RZOC 3CQZC 4BY7K 3GTPK 4A3IC 1SFOC 2VUMC 3I4MC 3RZDC 3GTGC 4C2MK 2JA5K 1HQMA 3FKIC 1TWGK 5C4XK 3S2HK 5IYBK 3S1RC 4Y52C 4AYBL 4BY1K 4XLNA 2B63C 3S16C 4MEYA 1I3QC 3S1NK 1Y1WK 3GTKK 4A3KK 2JA6K 1K83K 2R92K 3K7AK 3GTOC 3EQLA 4XSZA 3DXJA 4AYBD 4A3EK 3HOUC 4BXXK 4BBRK 2PA8L 2R7ZC 4QJVB 5IP9C 1SFOK 2WAQL 2A68A 3HOXC 2E2HC 3GTMK 4YG2A 2A69A 1SMYA 1BDFA 3S15K 3M4OK 4A3JK 2YU9C 3GTLK 4KMUA 3PO2C 3S2DK 3H0GC 4XSXA 4BY7C 3PO3K 2WAQD 4OIRA 5IP7C 2JA7K 4C2MC 2E2IC 1TWGC 2A6HA 3S17C 4MQ9A 4A3DK 3S1MC 3S1NC 1Y1WC 3GTKC 3GTJK 1K83C 4LK0A 2O5JA 4LK1A 1I6HK 4A3LK 1WCMC 3HOZC 4YFXA 4BXXC 4Q5SA 4BBRC 1R9TK 1TWFC 3S14K 4QJVA 5IYCC 3HOWC 4A3CK 5M3MK 3M4OC 4A3FK 5FJ8K 2NVYC 1I50K 5C4JC 4A93C 2NVXK 5IYDK 3GTLC 3S2DC 5M5XK 4G7OA 3HOVK 5C44K 2CW0A 1IW7A 5M5WK 2JA8K 2O5IA 3I4NK 4C3JK 4C3HK 4A3MK 2PA8D 1XPPA 2R93K 3GTPC 4X6AK 1TWHK 5M5YK 4OIOA 2NVTK 2JA5C 4NOIA 5C4XC 2E2JK 3S2HC 3HOYK 5IYBC 1I6HC 1TWAK 2NVQK 4A3BK 4BY1C 4A3CC 3H3VL 4A3IK 4A3FC 4A3KC 2JA6C 2R92C 4LLGA 1TWCK 3K7AC 1I50C 4YFKA 3FKIK 3RZDK 5IYDC 2VUMK 3GTGK 1Y1VK 4A3EC 4Y52K 5M3FK 3H3VD 3GTMC 5C44C 2B63K 3S15C 4OIQA 5FLMK 2JA8C 4QIWL 4A3JC 3GTOK 2A6EA 4A3GK 4C3HC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C3I K;  3S1Q K;  3PO3 C;  4Y7N K;  2R7Z K;  5IP9 K;  2JA7 C;  5D4D A;  2E2H K;  4QIW D;  3GTQ K;  2E2J C;  3HOY C;  4A3B C;  1TWA C;  2NVQ C;  3WOD A;  2YU9 K;  3M3Y K;  3PO2 K;  4A3D C;  4GZY A;  3H0G K;  4KN4 A;  3GTJ C;  4OIP A;  5IP7 K;  1TWC C;  2E2I K;  2BE5 A;  5TMC A;  4BBS K;  4A3L C;  1Y1V C;  2Y0S L;  5C3E K;  3RZO K;  2PPB A;  3CQZ K;  1R9T C;  4MEX A;  4XLP A;  4OIN A;  3S14 C;  2WB1 L;  1I6V A;  3I4M K;  5FLM C;  3S1M K;  2NVX C;  2Y0S D;  4A3G C;  1YNJ A;  3S1R K;  1WCM K;  4C3I C;  3S1Q C;  3HOZ K;  2WB1 D;  3HOV C;  4Y7N C;  4ZH4 A;  1I3Q K;  1TWF K;  5IYC K;  3HOW K;  4LJZ A;  4Q4Z A;  2PMZ L;  3S16 K;  3S17 K;  3GTQ C;  1ZYR A;  2NVY K;  4G7H A;  4KN7 A;  3HKZ L;  3I4N C;  5TMF A;  5C4J K;  4A93 K;  4C3J C;  4A3M C;  4X6A C;  3M3Y C;  2R93 C;  4JK1 A;  1YNN A;  1TWH C;  3HOU K;  4G7Z A;  2PMZ D;  2NVT C;  3HOX K;  3HKZ D;  4YFN A;  4BBS C;  5C3E C;  3RZO C;  3CQZ C;  4BY7 K;  3GTP K;  4A3I C;  1SFO C;  2VUM C;  3I4M C;  3RZD C;  3GTG C;  4C2M K;  2JA5 K;  1HQM A;  3FKI C;  1TWG K;  5C4X K;  3S2H K;  5IYB K;  3S1R C;  4Y52 C;  4AYB L;  4BY1 K;  4XLN A;  2B63 C;  3S16 C;  4MEY A;  1I3Q C;  3S1N K;  1Y1W K;  3GTK K;  4A3K K;  2JA6 K;  1K83 K;  2R92 K;  3K7A K;  3GTO C;  3EQL A;  4XSZ A;  3DXJ A;  4AYB D;  4A3E K;  3HOU C;  4BXX K;  4BBR K;  2PA8 L;  2R7Z C;  4QJV B;  5IP9 C;  1SFO K;  2WAQ L;  2A68 A;  3HOX C;  2E2H C;  3GTM K;  4YG2 A;  2A69 A;  1SMY A;  1BDF A;  3S15 K;  3M4O K;  4A3J K;  2YU9 C;  3GTL K;  4KMU A;  3PO2 C;  3S2D K;  3H0G C;  4XSX A;  4BY7 C;  3PO3 K;  2WAQ D;  4OIR A;  5IP7 C;  2JA7 K;  4C2M C;  2E2I C;  1TWG C;  2A6H A;  3S17 C;  4MQ9 A;  4A3D K;  3S1M C;  3S1N C;  1Y1W C;  3GTK C;  3GTJ K;  1K83 C;  4LK0 A;  2O5J A;  4LK1 A;  1I6H K;  4A3L K;  1WCM C;  3HOZ C;  4YFX A;  4BXX C;  4Q5S A;  4BBR C;  1R9T K;  1TWF C;  3S14 K;  4QJV A;  5IYC C;  3HOW C;  4A3C K;  5M3M K;  3M4O C;  4A3F K;  5FJ8 K;  2NVY C;  1I50 K;  5C4J C;  4A93 C;  2NVX K;  5IYD K;  3GTL C;  3S2D C;  5M5X K;  4G7O A;  3HOV K;  5C44 K;  2CW0 A;  1IW7 A;  5M5W K;  2JA8 K;  2O5I A;  3I4N K;  4C3J K;  4C3H K;  4A3M K;  2PA8 D;  1XPP A;  2R93 K;  3GTP C;  4X6A K;  1TWH K;  5M5Y K;  4OIO A;  2NVT K;  2JA5 C;  4NOI A;  5C4X C;  2E2J K;  3S2H C;  3HOY K;  5IYB C;  1I6H C;  1TWA K;  2NVQ K;  4A3B K;  4BY1 C;  4A3C C;  3H3V L;  4A3I K;  4A3F C;  4A3K C;  2JA6 C;  2R92 C;  4LLG A;  1TWC K;  3K7A C;  1I50 C;  4YFK A;  3FKI K;  3RZD K;  5IYD C;  2VUM K;  3GTG K;  1Y1V K;  4A3E C;  4Y52 K;  5M3F K;  3H3V D;  3GTM C;  5C44 C;  2B63 K;  3S15 C;  4OIQ A;  5FLM K;  2JA8 C;  4QIW L;  4A3J C;  3GTO K;  2A6E A;  4A3G K;  4C3H C; 
#chains in the Genus database with same CATH topology
 3G4C A;  2NVX A;  2GAG C;  2R7Z K;  3N3Y A;  5IP9 K;  1C0A A;  2KQ1 A;  4KM9 A;  2E2H K;  4QIW D;  3GTQ K;  2E2J C;  3TFH A;  3HOY C;  3M3Y K;  4KB2 A;  4A3D C;  3H0G K;  2D6F C;  5IP7 K;  4BLA A;  2BE5 A;  2E2I K;  5TMC A;  1TWH A;  4A3L C;  1F7U A;  3RZO K;  4XLP A;  4OIN A;  2P8T A;  3S1M K;  5FLM C;  2FQT A;  3CQZ A;  2Y0S D;  2L5N A;  1YNJ A;  4GT9 A;  5IYC K;  4M1X A;  1WSV A;  1I3Q A;  4C3J C;  4A3M C;  2R93 C;  1YNN A;  2ZJQ S;  3ADA C;  3HKZ D;  4KAW X;  2R7Z A;  4KAT A;  2E2H A;  4A3I C;  2XCQ A;  1UV7 A;  3GTG C;  5C4X K;  3H0G A;  1TWG K;  5IYB K;  2EBB A;  2E2I A;  2B63 C;  3GEH A;  3CF5 S;  3LPX A;  3S1N K;  4GFQ A;  3GTK K;  1K83 K;  2XCO A;  3K7A K;  3DXJ A;  1USM A;  2V6T A;  3GDZ A;  3FOE A;  3M4O K;  1ISE A;  4P5A A;  1BJT A;  1XXC A;  1L0W A;  3PO2 C;  3S2D K;  2KPU A;  3GIR A;  3N0B A;  4FM9 A;  3PO3 K;  4OIR A;  4WCE S;  2JA7 K;  5JVG S;  2A6H A;  2ZFZ A;  3JST A;  3GTJ K;  1IS1 A;  1WCM C;  4YFX A;  1TWF C;  3A8J A;  5M3M K;  4A3F K;  1DCH A;  5CHP A;  1XZQ B;  1XXB A;  3GTL C;  1ZBS A;  5HQH A;  4G7O A;  3HOV K;  2ZUF A;  2FQO A;  2O5I A;  5HL7 S;  1EFW A;  1O2B A;  3V4G A;  3CAG A;  3S2H C;  1B4A A;  4A3B K;  2NVQ K;  3OEP A;  1TWC K;  2XCR B;  3FKI K;  5IYD C;  1O24 A;  3GTJ A;  3GSI A;  5M3F K;  3H3V D;  5C44 C;  3S15 C;  1Y1V A;  3FOF A;  4WIL A;  4A3J C;  4WJ3 M;  4C3I K;  3S1Q K;  4G0V A;  1O29 A;  5DM7 S;  4G0W A;  4ILD A;  1TWA C;  2YU9 K;  3WOD A;  4GZY A;  1WIH A;  3FHZ A;  4KN4 A;  4OIP A;  5EGH A;  2ZJP S;  3BP8 C;  3CQZ K;  4GTE A;  3S14 C;  2WB1 L;  5TJ3 A;  1XZQ A;  5EGE A;  1J6V A;  4A3G C;  3HOZ K;  3FKI A;  3S16 K;  1JVI A;  1I3Q K;  3HOW K;  2PMZ L;  1YX2 A;  3GTQ C;  5HL8 A;  5C4J K;  4KN7 A;  4A93 K;  5TMF A;  1TWF A;  1WQH A;  3M3Y C;  3N0C A;  4JK1 A;  3PIP S;  3HOU K;  1PJ5 A;  2NVT C;  3HOX K;  1JQW A;  2P5M A;  4YFN A;  4P5B A;  3RZO C;  4AH6 A;  2YU9 A;  2VUM C;  2JA5 K;  2L3U A;  4KDD A;  5JFE A;  4Y52 C;  4AYB L;  4A3K K;  2R92 K;  1BS2 A;  4XSZ A;  4A3E K;  1Y1W A;  4BXX K;  4BBR K;  4RMF A;  1SMY A;  1BDF A;  2CFA B;  3ERE D;  1O2F B;  3HXA A;  4IOA S;  5L46 A;  5JVO A;  4XSX A;  2JH3 A;  1TWG C;  4PAA A;  3S17 C;  4MQ9 A;  5IOQ A;  3DLL S;  1WQF A;  4A3D K;  3L4K A;  3S1N C;  3GTK C;  1XZP B;  3Q3Q A;  1K83 C;  4LK1 A;  4A3L K;  4IOC S;  2JA5 A;  2ZJR S;  4GTF A;  4A3C K;  1USO A;  3BP3 A;  3M4O C;  5FJ8 K;  2NVY C;  3S2D C;  2R92 A;  1I50 A;  1YCL A;  2CW0 A;  4WF9 S;  1EQR A;  1EK8 A;  3TFI A;  3AQP A;  4C3J K;  4C3H K;  4A3M K;  2PA8 D;  3AH5 A;  2R93 K;  3GTP C;  4BKW A;  1F9N A;  2KWA A;  4FZB A;  4BY1 C;  2KXY A;  4A3I K;  4A3F C;  2JA6 C;  2GSO A;  3GTG K;  3A8I A;  1PJ6 A;  1Y1V K;  3GTM C;  2B63 K;  5E68 A;  1EI6 A;  1ZVU A;  4DDQ A;  2CFA A;  4GTC A;  4Y7N K;  5D4D A;  2PHC B;  4A3B C;  2NVQ C;  3TFJ A;  3PO2 K;  1TWC C;  1XZP A;  2R93 A;  4BBS K;  1ZQ1 C;  5C3E K;  2PPB A;  1R9T C;  3LYW A;  1O26 A;  1I6V A;  3I4M K;  2NVX C;  1O27 A;  3LAP A;  3S1R K;  1WCM K;  4C3I C;  3S1Q C;  3GTG A;  2WB1 D;  1TWF K;  4LJZ A;  4G7H A;  2B63 A;  3I4N C;  1O28 A;  4X6A C;  1X31 C;  1TWH C;  4G7Z A;  2PMZ D;  4LQY A;  4LOW A;  2ZUE A;  3CQZ C;  1WOS A;  4BY7 K;  1SFO C;  3RZD C;  3TTG A;  4C2M K;  1HQM A;  3GTP A;  3S0X A;  3S2H K;  5IOS A;  3IPJ A;  3S16 C;  3VA7 A;  1I3Q C;  1Y1W K;  1VGX A;  3GTO C;  4AYB D;  2GSU A;  3HOU C;  1DCO A;  3OPF A;  2R7Z C;  5IP9 C;  2WAQ L;  3HOX C;  2E2H C;  3S15 K;  1WCM A;  1VH2 A;  4A3J K;  4KMU A;  3H0G C;  4BLB A;  5IP7 C;  1HI9 A;  3GTL A;  2E2I C;  3AD8 C;  1J6X A;  3LAJ A;  1WQG A;  3S1M C;  1I6H K;  4XCH A;  4BXX C;  4BBR C;  3BUE A;  3S14 K;  4QJV A;  5IYC C;  1WOP A;  1RU0 A;  5DM6 S;  1WOO A;  4P9S A;  1I50 K;  1F7V A;  1IE0 A;  5M5W K;  4G0U A;  2JA8 K;  4KMA A;  1V5V A;  3T01 A;  1XPP A;  3ORE A;  4WFB S;  4GTA A;  4LR2 A;  5M5Y K;  4OIO A;  1JOE A;  2NVT K;  1ZXO A;  5C4X C;  2E2J K;  3HOY K;  5IYB C;  2GSN A;  4A3C C;  1TWA A;  2VUM K;  3K7A C;  4WJ4 A;  1WSR A;  1EH1 A;  1FEU A;  1IQ0 A;  1O2A A;  1SFO A;  4Y52 K;  3SZZ A;  5FLM K;  4QIW L;  2A6E A;  4KC6 A;  4C3H C;  4WFA S;  1GE9 A;  3PO3 C;  3GTO A;  2JA7 C;  3A8K A;  4KM8 A;  3GTQ A;  2Y3P A;  3GTJ C;  1WOR A;  2Y0S L;  1Y1V C;  3S17 K;  4MEX A;  1INN A;  3L4J A;  4KMH A;  2VUM A;  3HOV C;  4Y7N C;  4ZH4 A;  4Q4Z A;  1ZYR A;  2NVY K;  3HKZ L;  1DD5 A;  1F93 A;  4KB4 A;  5CJ9 A;  4O2D A;  4U67 S;  4BBS C;  4WFN S;  5C3E C;  1BGW A;  3GTP K;  4KAR A;  3I4M C;  3FKI C;  3S1R C;  3QX3 A;  4BY1 K;  4XLN A;  1TWG A;  4MEY A;  4KAS A;  2JA6 K;  3EQL A;  1VLO A;  4J3N A;  3T02 A;  3AD9 C;  3GTK A;  1G51 A;  1K83 A;  2PA8 L;  4QJV B;  3GTM K;  2A68 A;  3SZY A;  4YG2 A;  2A69 A;  3GEI A;  2YU9 C;  3GTL K;  4IO9 S;  4BY7 C;  2NVY A;  4GTB A;  2WAQ D;  4C2M C;  4GTL A;  5IOT A;  2V6U A;  2JA7 A;  3AD7 C;  3G4A A;  1Y1W C;  5JVH S;  4LK0 A;  2O5J A;  5IOR A;  3HOZ C;  3MML B;  1J98 A;  4Q5S A;  1R9T K;  3HOW C;  2NVX K;  4C45 A;  5C4J C;  4A93 C;  5IYD K;  1O25 A;  1IL2 A;  2JA6 A;  1PJ7 A;  5M5X K;  2GAH C;  5C44 K;  4PAB A;  1VRQ C;  1IW7 A;  1XXA A;  3GTM A;  3PIO S;  3I4N K;  1VJE A;  4X6A K;  1KQ4 A;  1TWH K;  4GTD A;  4KMD A;  2JA5 C;  4NOI A;  2V6S A;  3T00 A;  1I6H C;  1AB4 A;  1TWA K;  3AQO A;  3H3V L;  1DCP A;  2W7V A;  3NUH A;  4A3K C;  2R92 C;  1SFO K;  4LLG A;  3RZD K;  1I50 C;  4YFK A;  1B4B A;  1IBA A;  1J6W A;  4A3E C;  1TWC A;  4OIQ A;  2RH6 A;  2JA8 C;  1R9T A;  2RGR A;  3GTO K;  3GEE A;  4A3G K; 
#chains in the Genus database with same CATH homology
 4C3I K;  3S1Q K;  3PO3 C;  4Y7N K;  2R7Z K;  5IP9 K;  2JA7 C;  5D4D A;  2E2H K;  4QIW D;  3GTQ K;  2E2J C;  3HOY C;  4A3B C;  1TWA C;  2NVQ C;  3WOD A;  2YU9 K;  3M3Y K;  3PO2 K;  4A3D C;  4GZY A;  3H0G K;  4KN4 A;  3GTJ C;  4OIP A;  5IP7 K;  1TWC C;  2E2I K;  2BE5 A;  5TMC A;  4BBS K;  4A3L C;  1Y1V C;  2Y0S L;  5C3E K;  3RZO K;  2PPB A;  3CQZ K;  1R9T C;  4MEX A;  4XLP A;  4OIN A;  3S14 C;  2WB1 L;  1I6V A;  3I4M K;  5FLM C;  3S1M K;  2NVX C;  2Y0S D;  4A3G C;  1YNJ A;  3S1R K;  1WCM K;  4C3I C;  3S1Q C;  3HOZ K;  2WB1 D;  3HOV C;  4Y7N C;  4ZH4 A;  1I3Q K;  1TWF K;  5IYC K;  3HOW K;  4LJZ A;  4Q4Z A;  2PMZ L;  3S16 K;  3S17 K;  3GTQ C;  1ZYR A;  2NVY K;  4G7H A;  4KN7 A;  3HKZ L;  3I4N C;  5TMF A;  5C4J K;  4A93 K;  4C3J C;  4A3M C;  4X6A C;  3M3Y C;  2R93 C;  4JK1 A;  1YNN A;  1TWH C;  3HOU K;  4G7Z A;  2PMZ D;  2NVT C;  3HOX K;  3HKZ D;  4YFN A;  4BBS C;  5C3E C;  3RZO C;  3CQZ C;  4BY7 K;  3GTP K;  4A3I C;  1SFO C;  2VUM C;  3I4M C;  3RZD C;  3GTG C;  4C2M K;  2JA5 K;  1HQM A;  3FKI C;  1TWG K;  5C4X K;  3S2H K;  5IYB K;  3S1R C;  4Y52 C;  4AYB L;  4BY1 K;  4XLN A;  2B63 C;  3S16 C;  4MEY A;  1I3Q C;  3S1N K;  1Y1W K;  3GTK K;  4A3K K;  2JA6 K;  1K83 K;  2R92 K;  3K7A K;  3GTO C;  3EQL A;  4XSZ A;  3DXJ A;  4AYB D;  4A3E K;  3HOU C;  4BXX K;  4BBR K;  2PA8 L;  2R7Z C;  4QJV B;  5IP9 C;  1SFO K;  2WAQ L;  2A68 A;  3HOX C;  2E2H C;  3GTM K;  4YG2 A;  2A69 A;  1SMY A;  1BDF A;  3S15 K;  3M4O K;  4A3J K;  2YU9 C;  3GTL K;  4KMU A;  3PO2 C;  3S2D K;  3H0G C;  4XSX A;  4BY7 C;  3PO3 K;  2WAQ D;  4OIR A;  5IP7 C;  2JA7 K;  4C2M C;  2E2I C;  1TWG C;  2A6H A;  3S17 C;  4MQ9 A;  4A3D K;  3S1M C;  3S1N C;  1Y1W C;  3GTK C;  3GTJ K;  1K83 C;  4LK0 A;  2O5J A;  4LK1 A;  1I6H K;  4A3L K;  1WCM C;  3HOZ C;  4YFX A;  4BXX C;  4Q5S A;  4BBR C;  1R9T K;  1TWF C;  3S14 K;  4QJV A;  5IYC C;  3HOW C;  4A3C K;  5M3M K;  3M4O C;  4A3F K;  5FJ8 K;  2NVY C;  1I50 K;  5C4J C;  4A93 C;  2NVX K;  5IYD K;  3GTL C;  3S2D C;  5M5X K;  4G7O A;  3HOV K;  5C44 K;  2CW0 A;  1IW7 A;  5M5W K;  2JA8 K;  2O5I A;  3I4N K;  4C3J K;  4C3H K;  4A3M K;  2PA8 D;  1XPP A;  2R93 K;  3GTP C;  4X6A K;  1TWH K;  5M5Y K;  4OIO A;  2NVT K;  2JA5 C;  4NOI A;  5C4X C;  2E2J K;  3S2H C;  3HOY K;  5IYB C;  1I6H C;  1TWA K;  2NVQ K;  4A3B K;  4BY1 C;  4A3C C;  3H3V L;  4A3I K;  4A3F C;  4A3K C;  2JA6 C;  2R92 C;  4LLG A;  1TWC K;  3K7A C;  1I50 C;  4YFK A;  3FKI K;  3RZD K;  5IYD C;  2VUM K;  3GTG K;  1Y1V K;  4A3E C;  4Y52 K;  5M3F K;  3H3V D;  3GTM C;  5C44 C;  2B63 K;  3S15 C;  4OIQ A;  5FLM K;  2JA8 C;  4QIW L;  4A3J C;  3GTO K;  2A6E A;  4A3G K;  4C3H C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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