5IYDC

Human core-pic in the initial transcribing state (no iis)
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
275
structure length
275
Chain Sequence
MPYANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRLGLIPLISDDIVDKLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLISNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGVAFEYDPDNALRHTVYPKPEEWPKSEYSELDEDESQAPYDPNGKPERFYYNVESCGSLRPETIVLSALSGLKKKLSDLQTQLSHEIQSDVLTIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription, transferase/dna/rna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
publication title Near-atomic resolution visualization of human transcription promoter opening.
pubmed doi rcsb
source organism Homo sapiens
total genus 56
structure length 275
sequence length 275
ec nomenclature
pdb deposition date 2016-03-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
C PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 5iydC02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 5iydC01
4YFNA 4A3BC 5C44C 3S2HC 3H0GC 1I6HC 2O5JA 3S2DK 3GTQC 4C2MC 2E2HC 2A68A 3S1QC 5TMFA 2NVXK 4C3IK 1IW7A 4G7ZA 1TWCK 5C4XK 3I4MK 4OIPA 3GTKK 4LK0A 4A3JC 1BDFA 5IP7K 4OINA 3GTPC 3HOYK 3M4OK 4Y7NK 4YFKA 3K7AK 5C4JK 2JA7C 2NVQK 1WCMC 3S1NK 3S14C 4MQ9A 4BBSK 2R7ZC 3HOXK 4YFXA 3GTJC 4G7OA 4A3DK 3I4NK 3GTPK 3GTLC 4X6AK 3S1MK 4BBRC 5IYBC 2E2JK 5FJ8K 1TWAC 2VUMK 3HOVK 2JA8C 3CQZK 4XLNA 3HOWK 1YNNA 3PO2K 2YU9C 4A3CK 2CW0A 4BXXC 3S15C 3DXJA 3S14K 4A3KK 2E2IK 4A93C 4A3LK 2A69A 5M5XK 4BY7C 5IYBK 1TWGK 3GTGC 2B63K 3FKIC 5M5YK 5IP9C 3GTMC 4C3JC 4A3IC 4BXXK 1YNJA 5IYCC 2NVTC 2R93C 4XSZA 4C3HK 4A3BK 4Y52K 5C44K 3S2HK 4A3MC 3H0GK 1I6HK 4MEYA 3S16C 4YG2A 3GTQK 4MEXA 4Q5SA 1SFOC 4C2MK 3FKIK 1TWHC 3HKZL 1I6VA 5IP9K 2E2HK 3S1QK 4A3IK 2WAQL 2JA5C 4A3JK 4BY1C 5IYDC 3GTOC 2R92C 5D4DA 3S16K 5FLMC 1R9TC 4LK1A 3S1RC 4ZH4A 2JA7K 4OIRA 3HOZC 4A3EC 1WCMK 2PMZL 1HQMA 2NVYC 1I3QC 2R7ZK 2JA5K 3GTJK 5IYDK 3PO3C 1K83C 1XPPA 3GTLK 1Y1WC 4BBRK 1TWAK 4A3FC 1ZYRA 4XSXA 2JA8K 5M3FK 3RZDC 2YU9K 3M3YC 1I50C 1TWFC 3HOUC 3H3VL 3S15K 2PA8L 2JA6C 3RZOC 4A93K 3HKZD 4GZYA 4NOIA 4BY7K 2A6HA 5TMCA 2WAQD 2O5IA 4A3FK 3GTGK 3GTMK 2PPBA 3S2DC 2WB1L 4C3JK 5IYCK 4QIWL 2NVTK 5C4XC 2R93K 2NVXC 3I4MC 4C3IC 1TWCC 4AYBL 4A3MK 3GTKC 2Y0SL 2PMZD 5IP7C 3HOYC 1SFOK 3M4OC 4Q4ZA 1TWHK 3WODA 4Y7NC 4A3GC 4QJVB 5C4JC 3K7AC 4JK1A 2BE5A 5M3MK 4KMUA 4Y52C 2NVQC 4BY1K 3S1NC 5M5WK 3GTOK 4BBSC 3HOXC 5C3EC 2R92K 5FLMK 4KN4A 4OIOA 3H3VD 1R9TK 4A3DC 3I4NC 3S1RK 2PA8D 4LJZA 3S1MC 4X6AC 2VUMC 3HOVC 2E2JC 4QJVA 4A3EK 3HOZK 4A3GK 3CQZC 3HOWC 1I3QK 2NVYK 3S17C 3PO2C 4A3CC 3RZOK 3PO3K 1K83K 1Y1VC 3EQLA 2A6EA 2WB1D 4XLPA 4A3KC 5C3EK 1Y1WK 2E2IC 4QIWD 4A3LC 4LLGA 4AYBD 3RZDK 1TWGC 3M3YK 2B63C 2Y0SD 1I50K 1TWFK 3HOUK 3S17K 4G7HA 4KN7A 2JA6K 1SMYA 4C3HC 4OIQA 1Y1VK
chains in the Genus database with same CATH superfamily
4YFNA 3GTKA 5C44C 3H0GC 1WORA 1UV7A 2E2HC 2KWAA 3CF5S 5TMFA 2NVXK 4G7ZA 1L0WA 1BDFA 1Y1WA 4BKWA 3M4OK 3TTGA 1IS1A 2PHCB 1I50A 1F93A 2NVQK 1WCMC 3S1NK 3L4JA 2R7ZC 1Y1VA 1VRQC 4A3DK 4FZBA 3S1MK 5TJ3A 1TWAC 2JA8C 3HOWK 5CHPA 3S14K 3DXJA 1WSRA 2E2IK 5M5XK 3FOFA 1EK8A 1TWGK 1XZQA 1WOPA 4G0UA 4KB2A 4A3BK 3S2HK 3S16C 4MEXA 4Q5SA 5IP9K 1IE0A 1XXBA 4A3IK 4LQYA 4A3JK 4BY1C 1ZXOA 3AD7C 2R92C 5D4DA 4WCES 1R9TC 2FQOA 3T01A 4LK1A 4ZH4A 2B63A 4OIRA 4FM9A 4BLBA 3GTJK 5IYDK 3GTLK 4BBRK 1IQ0A 4A3FC 4XSXA 4LR2A 3OREA 5M3FK 1F7UA 3S15K 2PA8L 4KC6A 4A93K 4GZYA 2O5IA 2GSOA 3GTMK 2PPBA 4C3JK 2JA7A 5JFEA 4QIWL 2NVXC 1AB4A 3GSIA 1VLOA 2Y0SL 1YX2A 2PMZD 1J98A 4GTBA 3M4OC 1TWHK 1ISEA 4KMUA 1WOOA 2NVQC 3S1NC 3GTOK 1O2FB 5C3EC 4KN4A 3CAGA 5DM6S 4A3DC 3N0CA 1EH1A 3S1MC 1RU0A 4A3GK 3HOWC 2NVYK 2Y3PA 2R93A 3EQLA 2WB1D 1Y1WK 3LAPA 2E2IC 5JVHS 4WF9S 4AYBD 1TWGC 4O2DA 1I50K 1TWFK 1ZBSA 5C4XC 1SMYA 1TWCA 4OIQA 1Y1VK 4A3BC 3S2HC 4PAAA 4KATA 3S2DK 1O24A 4M1XA 1IW7A 1ZVUA 1F7VA 4KB4A 4LK0A 4C45A 4A3JC 4WJ4A 3GTPC 5IORA 1PJ5A 1XXCA 2V6SA 2RH6A 3MMLB 3GTJC 3JSTA 3G4CA 3GTLC 3S0XA 1VH2A 4BBRC 5IYBC 2E2JK 1VGXA 4G0WA 3PO2K 2GSUA 4A3CK 4BXXC 3S15C 4IOCS 4A93C 3H0GA 2A69A 1V5VA 2B63K 3FKIC 5M5YK 3GTMC 4C3JC 1O26A 4C3HK 4XSZA 3PIOS 4MEYA 1TWHC 1I6VA 3S1QK 1WCMA 2JA5C 3IPJA 4WJ3M 3GTOC 2JA7K 1USMA 1INNA 2NVYC 1O28A 5EGHA 1Y1WC 5HL7S 3GTQA 3GEIA 4GTEA 1WQFA 1C0AA 1I50C 1TWFC 2XCQA 1XXAA 3BP8C 4RMFA 1F9NA 4BY7K 3A8JA 3GTGK 2P5MA 3S2DC 4IOAS 2NVTK 2R93K 3TFIA 4A3MK 3L4KA 2KXYA 4P5BA 3QX3A 1JOEA 2YU9A 3FHZA 5M5WK 3HXAA 4OIOA 2XCOA 2PA8D 2JH3A 2ZUEA 3HOZK 2E2JC 4QJVA 1XZPA 3S17C 4P5AA 3PO2C 4A3CC 4QIWD 1SFOA 2FQTA 3RZDK 2B63C 2Y0SD 3HOUK 4KMAA 4G7HA 4C3HC 3PIPS 1PJ7A 3BP3A 2L5NA 2O5JA 5JVGS 2A68A 3S1QC 1I3QA 2GAHC 3I4MK 3GTKK 1EQRA 1K83A 5IOSA 4Y7NK 2P8TA 2JA7C 3Q3QA 3S14C 2JA6A 4MQ9A 3HOXK 3LYWA 4YFXA 3AQOA 1KQ4A 4X6AK 1IL2A 3N3YA 1YNNA 3DLLS 3ERED 2CW0A 2GAGC 3NUHA 4A3KK 4A3LK 1DD5A 4BY7C 1B4AA 2L3UA 4LOWA 3GTGC 5IP9C 3LAJA 3T02A 4A3IC 2NVTC 2R93C 4Y52K 3GDZA 3VA7A 4ILDA 4A3MC 1I6HK 3GTPA 4YG2A 3GTQK 4WFBS 1BGWA 4C2MK 2VUMA 4IO9S 4J3NA 3HKZL 3CQZA 2D6FC 2WAQL 4KASA 2ZUFA 3AQPA 5IYDC 4G0VA 5E68A 3S16K 3TFJA 1EFWA 4KAWX 4AH6A 3HOZC 1O25A 1HQMA 1PJ6A 3SZZA 4GTAA 3FOEA 1XPPA 2RGRA 4U67S 1ZYRA 1WOSA 4KMDA 2E2HA 3FKIA 3RZDC 4GTFA 2YU9K 3H3VL 3HOUC 2EBBA 3SZYA 4GTLA 4NOIA 4A3FK 1TWHA 4WILA 5IYCK 3I4MC 2R7ZA 2JA5A 3GIRA 3GTKC 2ZJPS 1SFOK 1TWAA 4Q4ZA 3WODA 4Y7NC 4A3GC 2BE5A 2NVYA 3HOXC 5FLMK 4WFNS 3S1RK 4LJZA 4X6AC 4A3EK 1I3QK 1TWFA 1O29A 5IOQA 1K83K 3PO3K 1YCLA 1Y1VC 5C3EK 4A3KC 5EGEA 4A3LC 3OPFA 4BLAA 4WFAS 3M3YK 2JA6K 3RZOK 3GEHA 2V6UA 4Y52C 1USOA 2R92A 1I6HC 1R9TA 1WQGA 3GTQC 4C2MC 2XCRB 1O27A 2V6TA 4DDQA 4C3IK 1TWCK 5C4XK 4OIPA 1BJTA 3AD8C 1G51A 4GFQA 5IP7K 4OINA 3HOYK 1VJEA 3LPXA 4YFKA 3K7AK 5C4JK 1JVIA 2ZFZA 1DCHA 2CFAB 3AH5A 4BBSK 4PABA 4G7OA 3I4NK 3T00A 3GTPK 1FEUA 2VUMK 3HOVK 5FJ8K 1X31C 4XLNA 3CQZK 2YU9C 2NVXA 4GT9A 3A8IA 3GEEA 4KMHA 4KM8A 5IYBK 3V4GA 1GE9A 1WIHA 4BXXK 1YNJA 5IYCC 1BS2A 4KDDA 5C44K 3H0GK 2GSNA 1IBAA 5JVOA 3OEPA 3N0BA 4GTDA 2KPUA 1SFOC 2E2HK 2W7VA 3FKIK 1EI6A 1O2BA 4XCHA 4KM9A 2E2IA 1J6XA 5FLMC 1XZQB 3S1RC 1TWGA 1JQWA 5HQHA 4A3EC 1WCMK 5HL8A 2PMZL 5L46A 1I3QC 2R7ZK 2JA5K 3PO3C 1K83C 5IOTA 2ZJRS 4KARA 1TWAK 2JA8K 3GTGA 3M3YC 1O2AA 3TFHA 2JA6C 1ZQ1C 3RZOC 3HKZD 2A6HA 5TMCA 1DCPA 2WAQD 2KQ1A 2ZJQS 2WB1L 4C3IC 1TWCC 4AYBL 3GTJA 3ADAC 3GTLA 5IP7C 3HOYC 1J6WA 1J6VA 4QJVB 5C4JC 3K7AC 4JK1A 1XZPB 5M3MK 4BY1K 4BBSC 2R92K 1WQHA 3H3VD 5CJ9A 1R9TK 3I4NC 3AD9C 2VUMC 3HOVC 3GTMA 1WSVA 3CQZC 4P9SA 4XLPA 2A6EA 1DCOA 4LLGA 1HI9A 5DM7S 3G4AA 4GTCA 3S17K 1B4BA 4KN7A 2CFAA 3BUEA 3A8KA 3GTOA
chains in the Genus database with same CATH topology
4YFNA 4A3BC 5C44C 3S2HC 3H0GC 1I6HC 2O5JA 3S2DK 3GTQC 4C2MC 2E2HC 2A68A 3S1QC 5TMFA 2NVXK 4C3IK 1IW7A 4G7ZA 1TWCK 5C4XK 3I4MK 4OIPA 3GTKK 4LK0A 4A3JC 1BDFA 5IP7K 4OINA 3GTPC 3HOYK 3M4OK 4Y7NK 4YFKA 3K7AK 5C4JK 2JA7C 2NVQK 1WCMC 3S1NK 3S14C 4MQ9A 4BBSK 2R7ZC 3HOXK 4YFXA 3GTJC 4G7OA 4A3DK 3I4NK 3GTPK 3GTLC 4X6AK 3S1MK 4BBRC 5IYBC 2E2JK 5FJ8K 1TWAC 2VUMK 3HOVK 2JA8C 3CQZK 4XLNA 3HOWK 1YNNA 3PO2K 2YU9C 4A3CK 2CW0A 4BXXC 3S15C 3DXJA 3S14K 4A3KK 2E2IK 4A93C 4A3LK 2A69A 5M5XK 4BY7C 5IYBK 1TWGK 3GTGC 2B63K 3FKIC 5M5YK 5IP9C 3GTMC 4C3JC 4A3IC 4BXXK 1YNJA 5IYCC 2NVTC 2R93C 4XSZA 4C3HK 4A3BK 4Y52K 5C44K 3S2HK 4A3MC 3H0GK 1I6HK 4MEYA 3S16C 4YG2A 3GTQK 4MEXA 4Q5SA 1SFOC 4C2MK 3FKIK 1TWHC 3HKZL 1I6VA 5IP9K 2E2HK 3S1QK 4A3IK 2WAQL 2JA5C 4A3JK 4BY1C 5IYDC 3GTOC 2R92C 5D4DA 3S16K 5FLMC 1R9TC 4LK1A 3S1RC 4ZH4A 2JA7K 4OIRA 3HOZC 4A3EC 1WCMK 2PMZL 1HQMA 2NVYC 1I3QC 2R7ZK 2JA5K 3GTJK 5IYDK 3PO3C 1K83C 1XPPA 3GTLK 1Y1WC 4BBRK 1TWAK 4A3FC 1ZYRA 4XSXA 2JA8K 5M3FK 3RZDC 2YU9K 3M3YC 1I50C 1TWFC 3HOUC 3H3VL 3S15K 2PA8L 2JA6C 3RZOC 4A93K 3HKZD 4GZYA 4NOIA 4BY7K 2A6HA 5TMCA 2WAQD 2O5IA 4A3FK 3GTGK 3GTMK 2PPBA 3S2DC 2WB1L 4C3JK 5IYCK 4QIWL 2NVTK 5C4XC 2R93K 2NVXC 3I4MC 4C3IC 1TWCC 4AYBL 4A3MK 3GTKC 2Y0SL 2PMZD 5IP7C 3HOYC 1SFOK 3M4OC 4Q4ZA 1TWHK 3WODA 4Y7NC 4A3GC 4QJVB 5C4JC 3K7AC 4JK1A 2BE5A 5M3MK 4KMUA 4Y52C 2NVQC 4BY1K 3S1NC 5M5WK 3GTOK 4BBSC 3HOXC 5C3EC 2R92K 5FLMK 4KN4A 4OIOA 3H3VD 1R9TK 4A3DC 3I4NC 3S1RK 2PA8D 4LJZA 3S1MC 4X6AC 2VUMC 3HOVC 2E2JC 4QJVA 4A3EK 3HOZK 4A3GK 3CQZC 3HOWC 1I3QK 2NVYK 3S17C 3PO2C 4A3CC 3RZOK 3PO3K 1K83K 1Y1VC 3EQLA 2A6EA 2WB1D 4XLPA 4A3KC 5C3EK 1Y1WK 2E2IC 4QIWD 4A3LC 4LLGA 4AYBD 3RZDK 1TWGC 3M3YK 2B63C 2Y0SD 1I50K 1TWFK 3HOUK 3S17K 4G7HA 4KN7A 2JA6K 1SMYA 4C3HC 4OIQA 1Y1VK
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YFN A;  4A3B C;  5C44 C;  3S2H C;  3H0G C;  1I6H C;  2O5J A;  3S2D K;  3GTQ C;  4C2M C;  2E2H C;  2A68 A;  3S1Q C;  5TMF A;  2NVX K;  4C3I K;  1IW7 A;  4G7Z A;  1TWC K;  5C4X K;  3I4M K;  4OIP A;  3GTK K;  4LK0 A;  4A3J C;  1BDF A;  5IP7 K;  4OIN A;  3GTP C;  3HOY K;  3M4O K;  4Y7N K;  4YFK A;  3K7A K;  5C4J K;  2JA7 C;  2NVQ K;  1WCM C;  3S1N K;  3S14 C;  4MQ9 A;  4BBS K;  2R7Z C;  3HOX K;  4YFX A;  3GTJ C;  4G7O A;  4A3D K;  3I4N K;  3GTP K;  3GTL C;  4X6A K;  3S1M K;  4BBR C;  5IYB C;  2E2J K;  5FJ8 K;  1TWA C;  2VUM K;  3HOV K;  2JA8 C;  3CQZ K;  4XLN A;  3HOW K;  1YNN A;  3PO2 K;  2YU9 C;  4A3C K;  2CW0 A;  4BXX C;  3S15 C;  3DXJ A;  3S14 K;  4A3K K;  2E2I K;  4A93 C;  4A3L K;  2A69 A;  5M5X K;  4BY7 C;  5IYB K;  1TWG K;  3GTG C;  2B63 K;  3FKI C;  5M5Y K;  5IP9 C;  3GTM C;  4C3J C;  4A3I C;  4BXX K;  1YNJ A;  5IYC C;  2NVT C;  2R93 C;  4XSZ A;  4C3H K;  4A3B K;  4Y52 K;  5C44 K;  3S2H K;  4A3M C;  3H0G K;  1I6H K;  4MEY A;  3S16 C;  4YG2 A;  3GTQ K;  4MEX A;  4Q5S A;  1SFO C;  4C2M K;  3FKI K;  1TWH C;  3HKZ L;  1I6V A;  5IP9 K;  2E2H K;  3S1Q K;  4A3I K;  2WAQ L;  2JA5 C;  4A3J K;  4BY1 C;  5IYD C;  3GTO C;  2R92 C;  5D4D A;  3S16 K;  5FLM C;  1R9T C;  4LK1 A;  3S1R C;  4ZH4 A;  2JA7 K;  4OIR A;  3HOZ C;  4A3E C;  1WCM K;  2PMZ L;  1HQM A;  2NVY C;  1I3Q C;  2R7Z K;  2JA5 K;  3GTJ K;  5IYD K;  3PO3 C;  1K83 C;  1XPP A;  3GTL K;  1Y1W C;  4BBR K;  1TWA K;  4A3F C;  1ZYR A;  4XSX A;  2JA8 K;  5M3F K;  3RZD C;  2YU9 K;  3M3Y C;  1I50 C;  1TWF C;  3HOU C;  3H3V L;  3S15 K;  2PA8 L;  2JA6 C;  3RZO C;  4A93 K;  3HKZ D;  4GZY A;  4NOI A;  4BY7 K;  2A6H A;  5TMC A;  2WAQ D;  2O5I A;  4A3F K;  3GTG K;  3GTM K;  2PPB A;  3S2D C;  2WB1 L;  4C3J K;  5IYC K;  4QIW L;  2NVT K;  5C4X C;  2R93 K;  2NVX C;  3I4M C;  4C3I C;  1TWC C;  4AYB L;  4A3M K;  3GTK C;  2Y0S L;  2PMZ D;  5IP7 C;  3HOY C;  1SFO K;  3M4O C;  4Q4Z A;  1TWH K;  3WOD A;  4Y7N C;  4A3G C;  4QJV B;  5C4J C;  3K7A C;  4JK1 A;  2BE5 A;  5M3M K;  4KMU A;  4Y52 C;  2NVQ C;  4BY1 K;  3S1N C;  5M5W K;  3GTO K;  4BBS C;  3HOX C;  5C3E C;  2R92 K;  5FLM K;  4KN4 A;  4OIO A;  3H3V D;  1R9T K;  4A3D C;  3I4N C;  3S1R K;  2PA8 D;  4LJZ A;  3S1M C;  4X6A C;  2VUM C;  3HOV C;  2E2J C;  4QJV A;  4A3E K;  3HOZ K;  4A3G K;  3CQZ C;  3HOW C;  1I3Q K;  2NVY K;  3S17 C;  3PO2 C;  4A3C C;  3RZO K;  3PO3 K;  1K83 K;  1Y1V C;  3EQL A;  2A6E A;  2WB1 D;  4XLP A;  4A3K C;  5C3E K;  1Y1W K;  2E2I C;  4QIW D;  4A3L C;  4LLG A;  4AYB D;  3RZD K;  1TWG C;  3M3Y K;  2B63 C;  2Y0S D;  1I50 K;  1TWF K;  3HOU K;  3S17 K;  4G7H A;  4KN7 A;  2JA6 K;  1SMY A;  4C3H C;  4OIQ A;  1Y1V K; 
#chains in the Genus database with same CATH topology
 4YFN A;  3GTK A;  5C44 C;  3H0G C;  1WOR A;  1UV7 A;  2E2H C;  2KWA A;  3CF5 S;  5TMF A;  2NVX K;  4G7Z A;  1L0W A;  1BDF A;  1Y1W A;  4BKW A;  3M4O K;  3TTG A;  1IS1 A;  2PHC B;  1I50 A;  1F93 A;  2NVQ K;  1WCM C;  3S1N K;  3L4J A;  2R7Z C;  1Y1V A;  1VRQ C;  4A3D K;  4FZB A;  3S1M K;  5TJ3 A;  1TWA C;  2JA8 C;  3HOW K;  5CHP A;  3S14 K;  3DXJ A;  1WSR A;  2E2I K;  5M5X K;  3FOF A;  1EK8 A;  1TWG K;  1XZQ A;  1WOP A;  4G0U A;  4KB2 A;  4A3B K;  3S2H K;  3S16 C;  4MEX A;  4Q5S A;  5IP9 K;  1IE0 A;  1XXB A;  4A3I K;  4LQY A;  4A3J K;  4BY1 C;  1ZXO A;  3AD7 C;  2R92 C;  5D4D A;  4WCE S;  1R9T C;  2FQO A;  3T01 A;  4LK1 A;  4ZH4 A;  2B63 A;  4OIR A;  4FM9 A;  4BLB A;  3GTJ K;  5IYD K;  3GTL K;  4BBR K;  1IQ0 A;  4A3F C;  4XSX A;  4LR2 A;  3ORE A;  5M3F K;  1F7U A;  3S15 K;  2PA8 L;  4KC6 A;  4A93 K;  4GZY A;  2O5I A;  2GSO A;  3GTM K;  2PPB A;  4C3J K;  2JA7 A;  5JFE A;  4QIW L;  2NVX C;  1AB4 A;  3GSI A;  1VLO A;  2Y0S L;  1YX2 A;  2PMZ D;  1J98 A;  4GTB A;  3M4O C;  1TWH K;  1ISE A;  4KMU A;  1WOO A;  2NVQ C;  3S1N C;  3GTO K;  1O2F B;  5C3E C;  4KN4 A;  3CAG A;  5DM6 S;  4A3D C;  3N0C A;  1EH1 A;  3S1M C;  1RU0 A;  4A3G K;  3HOW C;  2NVY K;  2Y3P A;  2R93 A;  3EQL A;  2WB1 D;  1Y1W K;  3LAP A;  2E2I C;  5JVH S;  4WF9 S;  4AYB D;  1TWG C;  4O2D A;  1I50 K;  1TWF K;  1ZBS A;  5C4X C;  1SMY A;  1TWC A;  4OIQ A;  1Y1V K;  4A3B C;  3S2H C;  4PAA A;  4KAT A;  3S2D K;  1O24 A;  4M1X A;  1IW7 A;  1ZVU A;  1F7V A;  4KB4 A;  4LK0 A;  4C45 A;  4A3J C;  4WJ4 A;  3GTP C;  5IOR A;  1PJ5 A;  1XXC A;  2V6S A;  2RH6 A;  3MML B;  3GTJ C;  3JST A;  3G4C A;  3GTL C;  3S0X A;  1VH2 A;  4BBR C;  5IYB C;  2E2J K;  1VGX A;  4G0W A;  3PO2 K;  2GSU A;  4A3C K;  4BXX C;  3S15 C;  4IOC S;  4A93 C;  3H0G A;  2A69 A;  1V5V A;  2B63 K;  3FKI C;  5M5Y K;  3GTM C;  4C3J C;  1O26 A;  4C3H K;  4XSZ A;  3PIO S;  4MEY A;  1TWH C;  1I6V A;  3S1Q K;  1WCM A;  2JA5 C;  3IPJ A;  4WJ3 M;  3GTO C;  2JA7 K;  1USM A;  1INN A;  2NVY C;  1O28 A;  5EGH A;  1Y1W C;  5HL7 S;  3GTQ A;  3GEI A;  4GTE A;  1WQF A;  1C0A A;  1I50 C;  1TWF C;  2XCQ A;  1XXA A;  3BP8 C;  4RMF A;  1F9N A;  4BY7 K;  3A8J A;  3GTG K;  2P5M A;  3S2D C;  4IOA S;  2NVT K;  2R93 K;  3TFI A;  4A3M K;  3L4K A;  2KXY A;  4P5B A;  3QX3 A;  1JOE A;  2YU9 A;  3FHZ A;  5M5W K;  3HXA A;  4OIO A;  2XCO A;  2PA8 D;  2JH3 A;  2ZUE A;  3HOZ K;  2E2J C;  4QJV A;  1XZP A;  3S17 C;  4P5A A;  3PO2 C;  4A3C C;  4QIW D;  1SFO A;  2FQT A;  3RZD K;  2B63 C;  2Y0S D;  3HOU K;  4KMA A;  4G7H A;  4C3H C;  3PIP S;  1PJ7 A;  3BP3 A;  2L5N A;  2O5J A;  5JVG S;  2A68 A;  3S1Q C;  1I3Q A;  2GAH C;  3I4M K;  3GTK K;  1EQR A;  1K83 A;  5IOS A;  4Y7N K;  2P8T A;  2JA7 C;  3Q3Q A;  3S14 C;  2JA6 A;  4MQ9 A;  3HOX K;  3LYW A;  4YFX A;  3AQO A;  1KQ4 A;  4X6A K;  1IL2 A;  3N3Y A;  1YNN A;  3DLL S;  3ERE D;  2CW0 A;  2GAG C;  3NUH A;  4A3K K;  4A3L K;  1DD5 A;  4BY7 C;  1B4A A;  2L3U A;  4LOW A;  3GTG C;  5IP9 C;  3LAJ A;  3T02 A;  4A3I C;  2NVT C;  2R93 C;  4Y52 K;  3GDZ A;  3VA7 A;  4ILD A;  4A3M C;  1I6H K;  3GTP A;  4YG2 A;  3GTQ K;  4WFB S;  1BGW A;  4C2M K;  2VUM A;  4IO9 S;  4J3N A;  3HKZ L;  3CQZ A;  2D6F C;  2WAQ L;  4KAS A;  2ZUF A;  3AQP A;  5IYD C;  4G0V A;  5E68 A;  3S16 K;  3TFJ A;  1EFW A;  4KAW X;  4AH6 A;  3HOZ C;  1O25 A;  1HQM A;  1PJ6 A;  3SZZ A;  4GTA A;  3FOE A;  1XPP A;  2RGR A;  4U67 S;  1ZYR A;  1WOS A;  4KMD A;  2E2H A;  3FKI A;  3RZD C;  4GTF A;  2YU9 K;  3H3V L;  3HOU C;  2EBB A;  3SZY A;  4GTL A;  4NOI A;  4A3F K;  1TWH A;  4WIL A;  5IYC K;  3I4M C;  2R7Z A;  2JA5 A;  3GIR A;  3GTK C;  2ZJP S;  1SFO K;  1TWA A;  4Q4Z A;  3WOD A;  4Y7N C;  4A3G C;  2BE5 A;  2NVY A;  3HOX C;  5FLM K;  4WFN S;  3S1R K;  4LJZ A;  4X6A C;  4A3E K;  1I3Q K;  1TWF A;  1O29 A;  5IOQ A;  1K83 K;  3PO3 K;  1YCL A;  1Y1V C;  5C3E K;  4A3K C;  5EGE A;  4A3L C;  3OPF A;  4BLA A;  4WFA S;  3M3Y K;  2JA6 K;  3RZO K;  3GEH A;  2V6U A;  4Y52 C;  1USO A;  2R92 A;  1I6H C;  1R9T A;  1WQG A;  3GTQ C;  4C2M C;  2XCR B;  1O27 A;  2V6T A;  4DDQ A;  4C3I K;  1TWC K;  5C4X K;  4OIP A;  1BJT A;  3AD8 C;  1G51 A;  4GFQ A;  5IP7 K;  4OIN A;  3HOY K;  1VJE A;  3LPX A;  4YFK A;  3K7A K;  5C4J K;  1JVI A;  2ZFZ A;  1DCH A;  2CFA B;  3AH5 A;  4BBS K;  4PAB A;  4G7O A;  3I4N K;  3T00 A;  3GTP K;  1FEU A;  2VUM K;  3HOV K;  5FJ8 K;  1X31 C;  4XLN A;  3CQZ K;  2YU9 C;  2NVX A;  4GT9 A;  3A8I A;  3GEE A;  4KMH A;  4KM8 A;  5IYB K;  3V4G A;  1GE9 A;  1WIH A;  4BXX K;  1YNJ A;  5IYC C;  1BS2 A;  4KDD A;  5C44 K;  3H0G K;  2GSN A;  1IBA A;  5JVO A;  3OEP A;  3N0B A;  4GTD A;  2KPU A;  1SFO C;  2E2H K;  2W7V A;  3FKI K;  1EI6 A;  1O2B A;  4XCH A;  4KM9 A;  2E2I A;  1J6X A;  5FLM C;  1XZQ B;  3S1R C;  1TWG A;  1JQW A;  5HQH A;  4A3E C;  1WCM K;  5HL8 A;  2PMZ L;  5L46 A;  1I3Q C;  2R7Z K;  2JA5 K;  3PO3 C;  1K83 C;  5IOT A;  2ZJR S;  4KAR A;  1TWA K;  2JA8 K;  3GTG A;  3M3Y C;  1O2A A;  3TFH A;  2JA6 C;  1ZQ1 C;  3RZO C;  3HKZ D;  2A6H A;  5TMC A;  1DCP A;  2WAQ D;  2KQ1 A;  2ZJQ S;  2WB1 L;  4C3I C;  1TWC C;  4AYB L;  3GTJ A;  3ADA C;  3GTL A;  5IP7 C;  3HOY C;  1J6W A;  1J6V A;  4QJV B;  5C4J C;  3K7A C;  4JK1 A;  1XZP B;  5M3M K;  4BY1 K;  4BBS C;  2R92 K;  1WQH A;  3H3V D;  5CJ9 A;  1R9T K;  3I4N C;  3AD9 C;  2VUM C;  3HOV C;  3GTM A;  1WSV A;  3CQZ C;  4P9S A;  4XLP A;  2A6E A;  1DCO A;  4LLG A;  1HI9 A;  5DM7 S;  3G4A A;  4GTC A;  3S17 K;  1B4B A;  4KN7 A;  2CFA A;  3BUE A;  3A8K A;  3GTO A; 
#chains in the Genus database with same CATH homology
 4YFN A;  4A3B C;  5C44 C;  3S2H C;  3H0G C;  1I6H C;  2O5J A;  3S2D K;  3GTQ C;  4C2M C;  2E2H C;  2A68 A;  3S1Q C;  5TMF A;  2NVX K;  4C3I K;  1IW7 A;  4G7Z A;  1TWC K;  5C4X K;  3I4M K;  4OIP A;  3GTK K;  4LK0 A;  4A3J C;  1BDF A;  5IP7 K;  4OIN A;  3GTP C;  3HOY K;  3M4O K;  4Y7N K;  4YFK A;  3K7A K;  5C4J K;  2JA7 C;  2NVQ K;  1WCM C;  3S1N K;  3S14 C;  4MQ9 A;  4BBS K;  2R7Z C;  3HOX K;  4YFX A;  3GTJ C;  4G7O A;  4A3D K;  3I4N K;  3GTP K;  3GTL C;  4X6A K;  3S1M K;  4BBR C;  5IYB C;  2E2J K;  5FJ8 K;  1TWA C;  2VUM K;  3HOV K;  2JA8 C;  3CQZ K;  4XLN A;  3HOW K;  1YNN A;  3PO2 K;  2YU9 C;  4A3C K;  2CW0 A;  4BXX C;  3S15 C;  3DXJ A;  3S14 K;  4A3K K;  2E2I K;  4A93 C;  4A3L K;  2A69 A;  5M5X K;  4BY7 C;  5IYB K;  1TWG K;  3GTG C;  2B63 K;  3FKI C;  5M5Y K;  5IP9 C;  3GTM C;  4C3J C;  4A3I C;  4BXX K;  1YNJ A;  5IYC C;  2NVT C;  2R93 C;  4XSZ A;  4C3H K;  4A3B K;  4Y52 K;  5C44 K;  3S2H K;  4A3M C;  3H0G K;  1I6H K;  4MEY A;  3S16 C;  4YG2 A;  3GTQ K;  4MEX A;  4Q5S A;  1SFO C;  4C2M K;  3FKI K;  1TWH C;  3HKZ L;  1I6V A;  5IP9 K;  2E2H K;  3S1Q K;  4A3I K;  2WAQ L;  2JA5 C;  4A3J K;  4BY1 C;  5IYD C;  3GTO C;  2R92 C;  5D4D A;  3S16 K;  5FLM C;  1R9T C;  4LK1 A;  3S1R C;  4ZH4 A;  2JA7 K;  4OIR A;  3HOZ C;  4A3E C;  1WCM K;  2PMZ L;  1HQM A;  2NVY C;  1I3Q C;  2R7Z K;  2JA5 K;  3GTJ K;  5IYD K;  3PO3 C;  1K83 C;  1XPP A;  3GTL K;  1Y1W C;  4BBR K;  1TWA K;  4A3F C;  1ZYR A;  4XSX A;  2JA8 K;  5M3F K;  3RZD C;  2YU9 K;  3M3Y C;  1I50 C;  1TWF C;  3HOU C;  3H3V L;  3S15 K;  2PA8 L;  2JA6 C;  3RZO C;  4A93 K;  3HKZ D;  4GZY A;  4NOI A;  4BY7 K;  2A6H A;  5TMC A;  2WAQ D;  2O5I A;  4A3F K;  3GTG K;  3GTM K;  2PPB A;  3S2D C;  2WB1 L;  4C3J K;  5IYC K;  4QIW L;  2NVT K;  5C4X C;  2R93 K;  2NVX C;  3I4M C;  4C3I C;  1TWC C;  4AYB L;  4A3M K;  3GTK C;  2Y0S L;  2PMZ D;  5IP7 C;  3HOY C;  1SFO K;  3M4O C;  4Q4Z A;  1TWH K;  3WOD A;  4Y7N C;  4A3G C;  4QJV B;  5C4J C;  3K7A C;  4JK1 A;  2BE5 A;  5M3M K;  4KMU A;  4Y52 C;  2NVQ C;  4BY1 K;  3S1N C;  5M5W K;  3GTO K;  4BBS C;  3HOX C;  5C3E C;  2R92 K;  5FLM K;  4KN4 A;  4OIO A;  3H3V D;  1R9T K;  4A3D C;  3I4N C;  3S1R K;  2PA8 D;  4LJZ A;  3S1M C;  4X6A C;  2VUM C;  3HOV C;  2E2J C;  4QJV A;  4A3E K;  3HOZ K;  4A3G K;  3CQZ C;  3HOW C;  1I3Q K;  2NVY K;  3S17 C;  3PO2 C;  4A3C C;  3RZO K;  3PO3 K;  1K83 K;  1Y1V C;  3EQL A;  2A6E A;  2WB1 D;  4XLP A;  4A3K C;  5C3E K;  1Y1W K;  2E2I C;  4QIW D;  4A3L C;  4LLG A;  4AYB D;  3RZD K;  1TWG C;  3M3Y K;  2B63 C;  2Y0S D;  1I50 K;  1TWF K;  3HOU K;  3S17 K;  4G7H A;  4KN7 A;  2JA6 K;  1SMY A;  4C3H C;  4OIQ A;  1Y1V K; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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