3CF5 | Genus

Total Genus 18

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	18
sequence length	175
structure length	175
Chain Sequence	MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Ribosome/antibiotic
publication title	Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin. pubmed doi rcsb
molecule keywords	50S RIBOSOMAL PROTEIN L33
total genus	18
structure length	175
sequence length	175
ec nomenclature
pdb deposition date	2008-03-02

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
S	PF01386	Ribosomal_L25p	Ribosomal L25p family
S	PF14693	Ribosomal_TL5_C	Ribosomal protein TL5, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.240.10	Mainly Beta	Beta Barrel	Ribosomal Protein L25; Chain P	Ribosomal Protein L25; Chain P	3cf5S01
2.170.120.20	Mainly Beta	Beta Complex	RNA Polymerase Alpha Subunit; Chain A, domain 2	Ribosomal protein L25, beta domain	3cf5S02

1EUQA 5GAGW 4JXXA 4IOCS 1NYLA 4H3SA 3PIPS 2RD2A 3DLLS 2ZJPS 1B75A 1EXDA 5DM6S 5HL7S 4U67S 5GAEW 1QRSA 2HZ7A 3PIOS 1ZJWA 1D6KA 1EUYA 1GTRA 1QTQA 1O0BA 5IZNA 1FEUA 5GAHW 1DFUP 5BNZA 4IOAS 4JXZA 4WFAS 4WFBS 1QRUA 5DM7S 3AIIA 5JVGS 4WCES 4JYZA 2RE8A 2ZJRS 4WF9S 5GADW 1QRTA 4WFNS 2ZJQS 3CF5S 5JVHS 4IO9S 3J7ZV 1O0CA 4P2BA 1GTSA 4UY88
chains in the Genus database with same CATH superfamily

2L3UA 4OIRA 4Q5SA 5GAGW 3K7AC 2A6HA 2YU9C 2O5IA 5IYBC 3X1LB 1NYLA 3S16C 3FKIC 4NOIA 5DM6S 1I6VA 4Y7NC 1R9TC 2NWAA 1HQMA 2KXYA 1QTQA 5IP9C 1GTRA 4A3FC 2NVQC 3HOWC 3GTOC 1FEUA 4JK1A 1VHYA 4H4KA 1UDXA 5TMFA 4IOAS 2KPUA 1TWAC 3PO2C 4YFKA 2CX8A 4A3CC 3S17C 2CW0A 2G5DA 2WB1D 5DM7S 3AIIA 4L69A 2PMZD 3PO3C 4WCES 4E8BA 2ZJRS 2Y0SD 3S2DC 2JA5C 2AE0X 2ZJQS 2A6EA 3CQZC 3J7ZV 2KQ1A 5IYCC 1I3QC 4G7ZA 1GTSA 4J3CA 2EGWA 1TWCC 2PICA 2JA7C 2WAQD 2PPBA 1Y1WC 4A3KC 2PNWA 3CZBA 4H3SA 1V6ZA 3PIPS 2B63C 5D4DA 3DLLS 2ZJPS 2PJJA 4V194 2E2IC 4X6AC 5HL7S 2A69A 1D6KA 4BXXC 4BBSC 4LJZA 2PA8D 1Z85A 3S14C 3WODA 5IZNA 5GAHW 1I50C 5BNZA 4KN4A 4AYBD 4XLNA 3GTGC 3S2HC 4YFNA 5HQHA 2JA8C 1QRUA 1SMYA 4WF9S 1ZYRA 3M4OC 3GTJC 5GADW 1QRTA 4WFNS 3LYWA 4XSZA 4C2MC 3S1NC 5C3EC 3RZOC 4XSXA 4G7HA 4LK1A 2NVXC 2GAEA 4C3IC 4MEYA 2R92C 4UY88 4KMUA 3GTLC 3I4NC 2Z0YA 1EUQA 4JXXA 5C44C 2VUMC 1SFOC 3W2WB 2A68A 4LK0A 3GTMC 4BBRC 2JA6C 2EGVA 4A3JC 1EXDA 4YG2A 4XLPA 2NVYC 3H0GC 4A3DC 4U67S 4A3IC 1QRSA 2HZ7A 1EUYA 1ZJWA 3DXJA 4Y52C 4Q4ZA 3GTPC 1O0BA 1DFUP 4A3MC 1K83C 3HOYC 2R93C 4BY1C 4YFXA 1YNJA 3S1QC 4WFBS 1VHKA 4C3HC 2RE8A 4C3JC 3GTKC 3S1MC 4A3BC 4QJVA 3CF5S 2PI8A 5JVHS 4IO9S 4QIWD 5IYDC 4A93C 3EQLA 5C4XC 1I6HC 3HOZC 2R7ZC 2BE5A 2E2HC 1WCMC 5TMCA 1YNNA 4ZH4A 5FLMC 4A3GC 1TWFC 1TWGC 4IOCS 5IP7C 3H3VD 4G7OA 4A3LC 3S1RC 3W2VB 2RD2A 1B75A 4MQ9A 3HOUC 3HOVC 5GAEW 4OIQA 3PIOS 3M3YC 1IW7A 3GTQC 2E2JC 3S15C 5C4JC 2NVTC 1Y1VC 4BY7C 4KN7A 4MEXA 3HKZD 2L5NA 3KW2A 4JXZA 4LLGA 4WFAS 4OIPA 4OINA 4GZYA 3I4MC 5JVGS 1TWHC 4JYZA 1NXZA 3RZDC 2G6GA 2O5JA 4OIOA 3HOXC 4A3EC 1O0CA 4P2BA 1BDFA
chains in the Genus database with same CATH topology

1EUQA 5GAGW 4JXXA 4IOCS 1NYLA 4H3SA 3X1LB 3W2WB 3PIPS 3W2VB 2RD2A 3DLLS 2ZJPS 4V194 1B75A 1EXDA 5DM6S 5HL7S 4U67S 5GAEW 1QRSA 2HZ7A 3PIOS 1ZJWA 1D6KA 1EUYA 1GTRA 1QTQA 1O0BA 5IZNA 1FEUA 5GAHW 1DFUP 4H4KA 5BNZA 1UDXA 4IOAS 4JXZA 4WFAS 4WFBS 1QRUA 5DM7S 3AIIA 5JVGS 4WCES 4JYZA 2RE8A 2ZJRS 4WF9S 5GADW 1QRTA 4WFNS 2ZJQS 3CF5S 5JVHS 4IO9S 3J7ZV 1O0CA 4P2BA 1GTSA 4UY88
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1EUQ A;  5GAG W;  4JXX A;  4IOC S;  1NYL A;  4H3S A;  3PIP S;  2RD2 A;  3DLL S;  2ZJP S;  1B75 A;  1EXD A;  5DM6 S;  5HL7 S;  4U67 S;  5GAE W;  1QRS A;  2HZ7 A;  3PIO S;  1ZJW A;  1D6K A;  1EUY A;  1GTR A;  1QTQ A;  1O0B A;  5IZN A;  1FEU A;  5GAH W;  1DFU P;  5BNZ A;  4IOA S;  4JXZ A;  4WFA S;  4WFB S;  1QRU A;  5DM7 S;  3AII A;  5JVG S;  4WCE S;  4JYZ A;  2RE8 A;  2ZJR S;  4WF9 S;  5GAD W;  1QRT A;  4WFN S;  2ZJQ S;  3CF5 S;  5JVH S;  4IO9 S;  3J7Z V;  1O0C A;  4P2B A;  1GTS A;  4UY8 8; 
#chains in the Genus database with same CATH topology
 2L3U A;  4OIR A;  4Q5S A;  5GAG W;  3K7A C;  2A6H A;  2YU9 C;  2O5I A;  5IYB C;  3X1L B;  1NYL A;  3S16 C;  3FKI C;  4NOI A;  5DM6 S;  1I6V A;  4Y7N C;  1R9T C;  2NWA A;  1HQM A;  2KXY A;  1QTQ A;  5IP9 C;  1GTR A;  4A3F C;  2NVQ C;  3HOW C;  3GTO C;  1FEU A;  4JK1 A;  1VHY A;  4H4K A;  1UDX A;  5TMF A;  4IOA S;  2KPU A;  1TWA C;  3PO2 C;  4YFK A;  2CX8 A;  4A3C C;  3S17 C;  2CW0 A;  2G5D A;  2WB1 D;  5DM7 S;  3AII A;  4L69 A;  2PMZ D;  3PO3 C;  4WCE S;  4E8B A;  2ZJR S;  2Y0S D;  3S2D C;  2JA5 C;  2AE0 X;  2ZJQ S;  2A6E A;  3CQZ C;  3J7Z V;  2KQ1 A;  5IYC C;  1I3Q C;  4G7Z A;  1GTS A;  4J3C A;  2EGW A;  1TWC C;  2PIC A;  2JA7 C;  2WAQ D;  2PPB A;  1Y1W C;  4A3K C;  2PNW A;  3CZB A;  4H3S A;  1V6Z A;  3PIP S;  2B63 C;  5D4D A;  3DLL S;  2ZJP S;  2PJJ A;  4V19 4;  2E2I C;  4X6A C;  5HL7 S;  2A69 A;  1D6K A;  4BXX C;  4BBS C;  4LJZ A;  2PA8 D;  1Z85 A;  3S14 C;  3WOD A;  5IZN A;  5GAH W;  1I50 C;  5BNZ A;  4KN4 A;  4AYB D;  4XLN A;  3GTG C;  3S2H C;  4YFN A;  5HQH A;  2JA8 C;  1QRU A;  1SMY A;  4WF9 S;  1ZYR A;  3M4O C;  3GTJ C;  5GAD W;  1QRT A;  4WFN S;  3LYW A;  4XSZ A;  4C2M C;  3S1N C;  5C3E C;  3RZO C;  4XSX A;  4G7H A;  4LK1 A;  2NVX C;  2GAE A;  4C3I C;  4MEY A;  2R92 C;  4UY8 8;  4KMU A;  3GTL C;  3I4N C;  2Z0Y A;  1EUQ A;  4JXX A;  5C44 C;  2VUM C;  1SFO C;  3W2W B;  2A68 A;  4LK0 A;  3GTM C;  4BBR C;  2JA6 C;  2EGV A;  4A3J C;  1EXD A;  4YG2 A;  4XLP A;  2NVY C;  3H0G C;  4A3D C;  4U67 S;  4A3I C;  1QRS A;  2HZ7 A;  1EUY A;  1ZJW A;  3DXJ A;  4Y52 C;  4Q4Z A;  3GTP C;  1O0B A;  1DFU P;  4A3M C;  1K83 C;  3HOY C;  2R93 C;  4BY1 C;  4YFX A;  1YNJ A;  3S1Q C;  4WFB S;  1VHK A;  4C3H C;  2RE8 A;  4C3J C;  3GTK C;  3S1M C;  4A3B C;  4QJV A;  3CF5 S;  2PI8 A;  5JVH S;  4IO9 S;  4QIW D;  5IYD C;  4A93 C;  3EQL A;  5C4X C;  1I6H C;  3HOZ C;  2R7Z C;  2BE5 A;  2E2H C;  1WCM C;  5TMC A;  1YNN A;  4ZH4 A;  5FLM C;  4A3G C;  1TWF C;  1TWG C;  4IOC S;  5IP7 C;  3H3V D;  4G7O A;  4A3L C;  3S1R C;  3W2V B;  2RD2 A;  1B75 A;  4MQ9 A;  3HOU C;  3HOV C;  5GAE W;  4OIQ A;  3PIO S;  3M3Y C;  1IW7 A;  3GTQ C;  2E2J C;  3S15 C;  5C4J C;  2NVT C;  1Y1V C;  4BY7 C;  4KN7 A;  4MEX A;  3HKZ D;  2L5N A;  3KW2 A;  4JXZ A;  4LLG A;  4WFA S;  4OIP A;  4OIN A;  4GZY A;  3I4M C;  5JVG S;  1TWH C;  4JYZ A;  1NXZ A;  3RZD C;  2G6G A;  2O5J A;  4OIO A;  3HOX C;  4A3E C;  1O0C A;  4P2B A;  1BDF A; 
#chains in the Genus database with same CATH homology
 1EUQ A;  5GAG W;  4JXX A;  4IOC S;  1NYL A;  4H3S A;  3X1L B;  3W2W B;  3PIP S;  3W2V B;  2RD2 A;  3DLL S;  2ZJP S;  4V19 4;  1B75 A;  1EXD A;  5DM6 S;  5HL7 S;  4U67 S;  5GAE W;  1QRS A;  2HZ7 A;  3PIO S;  1ZJW A;  1D6K A;  1EUY A;  1GTR A;  1QTQ A;  1O0B A;  5IZN A;  1FEU A;  5GAH W;  1DFU P;  4H4K A;  5BNZ A;  1UDX A;  4IOA S;  4JXZ A;  4WFA S;  4WFB S;  1QRU A;  5DM7 S;  3AII A;  5JVG S;  4WCE S;  4JYZ A;  2RE8 A;  2ZJR S;  4WF9 S;  5GAD W;  1QRT A;  4WFN S;  2ZJQ S;  3CF5 S;  5JVH S;  4IO9 S;  3J7Z V;  1O0C A;  4P2B A;  1GTS A;  4UY8 8;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3CF5S

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations