3TV2A

Structure of a class ii fumarate hydratase from burkholderia pseudomallei
Total Genus 178
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
178
sequence length
457
structure length
457
Chain Sequence
RMERDTFGEIAVPAARLWGAQTQRSLQNFKISTEKQSPELIHALALIKRAAAAVNLELGVLAQDKANAIVAAADEIIAGRHADEFPLAVWQTGSGTQTNMNLNEVIANRASELLGGERGESRAVHPNDDVNRGQSSNDVFPTAMHIAAARAIVDHLLPALRTLRATLDAKAAAFADIVKIGRTHLQDATPLTLGQEFSGYVAQLDQGIRHVEAALPHLYELAQGGTAVGTGLNAHPKFAAGVAAEIGRLTGLPFVSAPNKFEVMAAADALVFAHGALKTVAASLMKIANDIRWLASGPRCGLGELSIPENEPGSSIMPGKVNPTQSEAVTMLCCQVFGNDVAVNFGGASGNFELNVFRPMIAHNVLQSVRLLADGAQGFNDHCAVGIEPNRARIDALLNESLMLVTALNPHIGYDKAAQIAKKAHKEGTTLKAAALALGYVTDAQFDEWVRPEHMVG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a class II fumarate hydratase from Burkholderia pseudomallei
rcsb
molecule tags Lyase
source organism Burkholderia pseudomallei
molecule keywords Fumarate hydratase, class II
total genus 178
structure length 457
sequence length 457
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2011-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 3tv2A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3tv2A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3tv2A02
2X75A 2HVGA 2RJRA 4C5UA 1YFEA 1TJ7A 2RJSA 2O7FA 1TJUA 2O7BA 1J3UA 3C8TA 1TJWA 1XWOA 4MX2A 3CZOA 4C5RA 2O7DA 1K62A 4CQ5A 1Y2MA 4APBA 1VDKA 4EFCA 4C5SA 2NYNA 1GKMA 2PTSA 2E9FA 4ADMA 1AUWA 1Q5NA 2FUSA 3E04A 4HGVA 1FUPA 3OCFA 3KDYA 1C3UA 2PTRA 5F91A 3RRPA 2QVEA 4APAA 1RE5A 3GZHA 3R6YA 2PTQA 1JSWA 3UNVA 1T6PA 1YFMA 1K7WA 2PFMA 3BHGA 4C6GA 1T6JA 1U15A 3GTDA 2NYFA 3R6VA 1U16A 1FUQA 2OHYA 3QBPA 2YIIA 1HY0A 4V2RA 1DCNA 4FLCA 2O78A 2VD6A 1YISA 4BABA 4V2QA 3NO9A 1DOFA 1FURA 1FUOA 4FFXA 2O6YA 1C3CA 3KDZA 5EYTA 1B8FA 4ADLA 5F92A 3NZ4A 4NLEA 1GK3A 5HW2A 5EYVA 1GK2A 2J91A 1TJVA 2O7EA 1I0AA 4BAAA 4EEIA 3RD8A 3R6QA 4NSLA 1W27A 3TV2A 3OCEA 5D6BA 1EB4A 2QGAB 1KQ7A 1GKJA 1HY1A
chains in the Genus database with same CATH superfamily
5M0IA 2X75A 2HVGA 2RJRA 4MUMA 4IQJM 4C5UA 2JAWA 1YFEA 1TJ7A 2RJSA 2RCNA 1XL7A 2O7FA 1TJUA 3F4TA 2O7BA 1J3UA 4MWOA 3C8TA 1TJWA 2VL7A 1XWOA 4MX2A 3CZOA 4C5RA 1Z4KA 4L6CA 2O7DA 1K62A 4CQ5A 2D27A 1Y2MA 4APBA 2JAOA 2FENA 1VDKA 4EFCA 4C5SA 2NYNA 1GKMA 2PTSA 2E9FA 4ADMA 1AUWA 1Q5NA 1Z4MA 2FUSA 1Q92A 3E04A 4HGVA 1Q91A 1FUPA 3CI0K 3OCFA 3KDYA 1C3UA 2PTRA 5F91A 3RRPA 2QVEA 1T9HA 4APAA 1RE5A 4YIHA 3GZHA 3R6YA 2I7DA 1Z4PX 2PTQA 1JSWA 3UNVA 1T6PA 1YFMA 1K7WA 2VSFA 2PFMA 1Z4QA 3BHGA 4C6GA 2YV5A 3BWVA 1T6JA 1U15A 5H8WA 3GTDA 4A15A 2NYFA 3R6VA 1U16A 1FUQA 4E88A 2OHYA 3QBPA 2YIIA 1IW7D 1HY0A 4V2RA 1DCNA 4FLCA 2O78A 2VD6A 1YISA 4BABA 3F4RA 4V2QA 4L57A 3NO9A 1DOFA 1FURA 1FUOA 4FFXA 2O6YA 1C3CA 3KDZA 5EYTA 1B8FA 4ADLA 1XMDA 3CRW1 3F4SA 4NFLA 5F92A 2JAUA 3NZ4A 1XL8A 4NLEA 1GK3A 5HW2A 5EYVA 1U0LA 3U13A 1GK2A 1Z4JA 3U19A 2J91A 1TJVA 2O7EA 1I0AA 2D28C 4BAAA 5M0JA 1XMCA 4EEIA 4WNLA 1Z4LA 3RD8A 3R6QA 4NSLA 1W27A 3TV2A 2JARA 1Z4IA 4YIKA 3OCEA 3CRVA 1XLYA 5D6BA 4L6AA 2QGAB 1EB4A 1KQ7A 2FELA 1MH9A 1GKJA 1HY1A
chains in the Genus database with same CATH topology
2X75A 2HVGA 2RJRA 4C5UA 1YFEA 1TJ7A 2RJSA 2O7FA 1TJUA 2O7BA 1J3UA 3C8TA 1TJWA 1XWOA 4MX2A 3CZOA 4C5RA 2O7DA 1K62A 4CQ5A 1Y2MA 4APBA 1VDKA 4EFCA 4C5SA 2NYNA 1GKMA 2PTSA 2E9FA 4ADMA 1AUWA 1Q5NA 2FUSA 3E04A 4HGVA 1FUPA 3OCFA 3KDYA 1C3UA 2PTRA 5F91A 3RRPA 2QVEA 4APAA 1RE5A 3GZHA 3R6YA 2PTQA 1JSWA 3UNVA 1T6PA 1YFMA 1K7WA 2PFMA 3BHGA 4C6GA 1T6JA 1U15A 3GTDA 2NYFA 3R6VA 1U16A 1FUQA 2OHYA 3QBPA 2YIIA 1HY0A 4V2RA 1DCNA 4FLCA 2O78A 2VD6A 1YISA 4BABA 4V2QA 3NO9A 1DOFA 1FURA 1FUOA 4FFXA 2O6YA 1C3CA 3KDZA 5EYTA 1B8FA 4ADLA 5F92A 3NZ4A 4NLEA 1GK3A 5HW2A 5EYVA 1GK2A 2J91A 1TJVA 2O7EA 1I0AA 4BAAA 4EEIA 3RD8A 3R6QA 4NSLA 1W27A 3TV2A 3OCEA 5D6BA 1EB4A 2QGAB 1KQ7A 1GKJA 1HY1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2X75 A;  2HVG A;  2RJR A;  4C5U A;  1YFE A;  1TJ7 A;  2RJS A;  2O7F A;  1TJU A;  2O7B A;  1J3U A;  3C8T A;  1TJW A;  1XWO A;  4MX2 A;  3CZO A;  4C5R A;  2O7D A;  1K62 A;  4CQ5 A;  1Y2M A;  4APB A;  1VDK A;  4EFC A;  4C5S A;  2NYN A;  1GKM A;  2PTS A;  2E9F A;  4ADM A;  1AUW A;  1Q5N A;  2FUS A;  3E04 A;  4HGV A;  1FUP A;  3OCF A;  3KDY A;  1C3U A;  2PTR A;  5F91 A;  3RRP A;  2QVE A;  4APA A;  1RE5 A;  3GZH A;  3R6Y A;  2PTQ A;  1JSW A;  3UNV A;  1T6P A;  1YFM A;  1K7W A;  2PFM A;  3BHG A;  4C6G A;  1T6J A;  1U15 A;  3GTD A;  2NYF A;  3R6V A;  1U16 A;  1FUQ A;  2OHY A;  3QBP A;  2YII A;  1HY0 A;  4V2R A;  1DCN A;  4FLC A;  2O78 A;  2VD6 A;  1YIS A;  4BAB A;  4V2Q A;  3NO9 A;  1DOF A;  1FUR A;  1FUO A;  4FFX A;  2O6Y A;  1C3C A;  3KDZ A;  5EYT A;  1B8F A;  4ADL A;  5F92 A;  3NZ4 A;  4NLE A;  1GK3 A;  5HW2 A;  5EYV A;  1GK2 A;  2J91 A;  1TJV A;  2O7E A;  1I0A A;  4BAA A;  4EEI A;  3RD8 A;  3R6Q A;  4NSL A;  1W27 A;  3TV2 A;  3OCE A;  5D6B A;  1EB4 A;  2QGA B;  1KQ7 A;  1GKJ A;  1HY1 A; 
#chains in the Genus database with same CATH topology
 5M0I A;  2X75 A;  2HVG A;  2RJR A;  4MUM A;  4IQJ M;  4C5U A;  2JAW A;  1YFE A;  1TJ7 A;  2RJS A;  2RCN A;  1XL7 A;  2O7F A;  1TJU A;  3F4T A;  2O7B A;  1J3U A;  4MWO A;  3C8T A;  1TJW A;  2VL7 A;  1XWO A;  4MX2 A;  3CZO A;  4C5R A;  1Z4K A;  4L6C A;  2O7D A;  1K62 A;  4CQ5 A;  2D27 A;  1Y2M A;  4APB A;  2JAO A;  2FEN A;  1VDK A;  4EFC A;  4C5S A;  2NYN A;  1GKM A;  2PTS A;  2E9F A;  4ADM A;  1AUW A;  1Q5N A;  1Z4M A;  2FUS A;  1Q92 A;  3E04 A;  4HGV A;  1Q91 A;  1FUP A;  3CI0 K;  3OCF A;  3KDY A;  1C3U A;  2PTR A;  5F91 A;  3RRP A;  2QVE A;  1T9H A;  4APA A;  1RE5 A;  4YIH A;  3GZH A;  3R6Y A;  2I7D A;  1Z4P X;  2PTQ A;  1JSW A;  3UNV A;  1T6P A;  1YFM A;  1K7W A;  2VSF A;  2PFM A;  1Z4Q A;  3BHG A;  4C6G A;  2YV5 A;  3BWV A;  1T6J A;  1U15 A;  5H8W A;  3GTD A;  4A15 A;  2NYF A;  3R6V A;  1U16 A;  1FUQ A;  4E88 A;  2OHY A;  3QBP A;  2YII A;  1IW7 D;  1HY0 A;  4V2R A;  1DCN A;  4FLC A;  2O78 A;  2VD6 A;  1YIS A;  4BAB A;  3F4R A;  4V2Q A;  4L57 A;  3NO9 A;  1DOF A;  1FUR A;  1FUO A;  4FFX A;  2O6Y A;  1C3C A;  3KDZ A;  5EYT A;  1B8F A;  4ADL A;  1XMD A;  3CRW 1;  3F4S A;  4NFL A;  5F92 A;  2JAU A;  3NZ4 A;  1XL8 A;  4NLE A;  1GK3 A;  5HW2 A;  5EYV A;  1U0L A;  3U13 A;  1GK2 A;  1Z4J A;  3U19 A;  2J91 A;  1TJV A;  2O7E A;  1I0A A;  2D28 C;  4BAA A;  5M0J A;  1XMC A;  4EEI A;  4WNL A;  1Z4L A;  3RD8 A;  3R6Q A;  4NSL A;  1W27 A;  3TV2 A;  2JAR A;  1Z4I A;  4YIK A;  3OCE A;  3CRV A;  1XLY A;  5D6B A;  4L6A A;  2QGA B;  1EB4 A;  1KQ7 A;  2FEL A;  1MH9 A;  1GKJ A;  1HY1 A; 
#chains in the Genus database with same CATH homology
 2X75 A;  2HVG A;  2RJR A;  4C5U A;  1YFE A;  1TJ7 A;  2RJS A;  2O7F A;  1TJU A;  2O7B A;  1J3U A;  3C8T A;  1TJW A;  1XWO A;  4MX2 A;  3CZO A;  4C5R A;  2O7D A;  1K62 A;  4CQ5 A;  1Y2M A;  4APB A;  1VDK A;  4EFC A;  4C5S A;  2NYN A;  1GKM A;  2PTS A;  2E9F A;  4ADM A;  1AUW A;  1Q5N A;  2FUS A;  3E04 A;  4HGV A;  1FUP A;  3OCF A;  3KDY A;  1C3U A;  2PTR A;  5F91 A;  3RRP A;  2QVE A;  4APA A;  1RE5 A;  3GZH A;  3R6Y A;  2PTQ A;  1JSW A;  3UNV A;  1T6P A;  1YFM A;  1K7W A;  2PFM A;  3BHG A;  4C6G A;  1T6J A;  1U15 A;  3GTD A;  2NYF A;  3R6V A;  1U16 A;  1FUQ A;  2OHY A;  3QBP A;  2YII A;  1HY0 A;  4V2R A;  1DCN A;  4FLC A;  2O78 A;  2VD6 A;  1YIS A;  4BAB A;  4V2Q A;  3NO9 A;  1DOF A;  1FUR A;  1FUO A;  4FFX A;  2O6Y A;  1C3C A;  3KDZ A;  5EYT A;  1B8F A;  4ADL A;  5F92 A;  3NZ4 A;  4NLE A;  1GK3 A;  5HW2 A;  5EYV A;  1GK2 A;  2J91 A;  1TJV A;  2O7E A;  1I0A A;  4BAA A;  4EEI A;  3RD8 A;  3R6Q A;  4NSL A;  1W27 A;  3TV2 A;  3OCE A;  5D6B A;  1EB4 A;  2QGA B;  1KQ7 A;  1GKJ A;  1HY1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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