4HGVA

Crystal structure of a fumarate hydratase
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
461
structure length
456
Chain Sequence
STRTETDTFGPIEVASDRYWGAQAQRSLGNFKIGWEKQPLAIVRALGIVKQAAARANMALGRLDPAIGDAIVKAAQEVIDGKLDEHFPLVVWQTGSGTQSNMNANEVVSNRAIELLGGVMGSKKPVHPNDHVNMSQSSNDTYPTAMHIACAERVIHDLLPALKHLHKALEEKVKAFDHIIKIGRTHTQDATPLTLGQEFSGYAAQVASSIKRIEMTLPGLCELAQGGTAVGTGLNAPVGFAEKVAEEIAAITGIGFTSAPNKFEALAAHDSMVFSHGAINATAAALFKIANDIRFLGSGPRSGLGELSLPENEPGSKVNPTQCEALTQVCVQVFGNHAALTFAGSQGHFELNVYNPLMAYNFLQSVQLLADAAISFTDNCVVGIEAREDNIKAALDRSLMLVTALAPKIGYDNAAKIAKTAHKNGTTLREEAVGGGYVTDEEFDAVVRPETMIGPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
source organism Sinorhizobium meliloti
publication title Crystal structure of a fumarate hydratase
rcsb
molecule keywords Fumarate hydratase class II
total genus 158
structure length 456
sequence length 461
chains with identical sequence B, C, D
ec nomenclature ec 4.2.1.2: Fumarate hydratase.
pdb deposition date 2012-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00206 Lyase_1 Lyase
A PF10415 FumaraseC_C Fumarase C C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.40.30 Mainly Alpha Orthogonal Bundle Ribonucleotide Reductase Protein R1; domain 1 Fumarase/aspartase (C-terminal domain) 4hgvA03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 4hgvA01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 4hgvA02
1JSWA 5EYTA 2E9FA 5F92A 1J3UA 4EEIA 2OHYA 3R6YA 3BHGA 5D6BA 2FUSA 3NZ4A 1U15A 2YIIA 1W27A 3R6VA 4FLCA 1FURA 3R6QA 1EB4A 3OCEA 4BAAA 1XWOA 2VD6A 4C5SA 3QBPA 4V2RA 1C3CA 1TJUA 2HVGA 5F91A 1DOFA 4CQ5A 4C5RA 1RE5A 5HW2A 3KDYA 1Y2MA 1YFEA 4C6GA 2PTSA 1FUPA 4ADLA 1YFMA 2PFMA 3TV2A 1K62A 1TJWA 1C3UA 2J91A 4EFCA 1KQ7A 1TJ7A 2X75A 4C5UA 1YISA 2O7BA 1DCNA 2O6YA 4NLEA 3OCFA 3RD8A 1GK3A 2O7FA 3NO9A 1FUQA 2NYNA 1TJVA 4ADMA 2O7DA 2PTRA 1HY1A 3CZOA 4NSLA 1HY0A 1GK2A 3RRPA 2QVEA 1AUWA 1T6PA 1U16A 4APBA 2O78A 4HGVA 4APAA 2RJRA 1B8FA 1I0AA 2RJSA 2QGAB 1K7WA 3UNVA 4FFXA 1VDKA 3KDZA 3GZHA 3C8TA 3GTDA 1T6JA 3E04A 4MX2A 1Q5NA 4V2QA 2O7EA 1GKMA 1FUOA 1GKJA 2PTQA 5EYVA 4BABA 2NYFA
chains in the Genus database with same CATH superfamily
1JSWA 2FENA 5EYTA 2E9FA 5F92A 1J3UA 4EEIA 5H8WA 2OHYA 3R6YA 3F4SA 4A15A 3F4RA 3BHGA 3CRVA 5D6BA 1Z4MA 2FUSA 3NZ4A 1U15A 2YIIA 1W27A 3R6VA 4FLCA 1FURA 3R6QA 1EB4A 3OCEA 4BAAA 1XWOA 1Z4KA 2D28C 2VD6A 4C5SA 1IW7D 3QBPA 4V2RA 2JAWA 1C3CA 2JARA 1XL8A 1TJUA 2HVGA 5F91A 1DOFA 4CQ5A 2VL7A 1T9HA 4C5RA 1RE5A 5HW2A 3KDYA 1Y2MA 1YFEA 4C6GA 4WNLA 2PTSA 1FUPA 4ADLA 1YFMA 2PFMA 3F4TA 3TV2A 1K62A 1Z4PX 1TJWA 2YV5A 1C3UA 2J91A 4NFLA 4EFCA 1KQ7A 1TJ7A 2X75A 4C5UA 1YISA 2O7BA 1DCNA 2O6YA 2RCNA 4L6CA 1XL7A 4NLEA 2VSFA 3OCFA 3RD8A 1GK3A 2O7FA 3NO9A 1Q91A 4MUMA 1FUQA 2NYNA 1TJVA 4ADMA 4IQJM 5M0IA 2O7DA 2PTRA 1XLYA 1HY1A 4E88A 3CZOA 1XMDA 4NSLA 2FELA 2D27A 1HY0A 3BWVA 1GK2A 4MWOA 3RRPA 2QVEA 1AUWA 1Z4QA 1T6PA 1U16A 4APBA 2O78A 4HGVA 1MH9A 3CRW1 5M0JA 2JAUA 4APAA 2RJRA 1Z4LA 1B8FA 1I0AA 1Z4IA 2RJSA 1Z4JA 2QGAB 4L57A 1K7WA 3UNVA 2JAOA 4FFXA 1Q92A 1VDKA 4L6AA 3KDZA 3GZHA 4YIKA 3C8TA 3GTDA 1T6JA 1XMCA 3E04A 4MX2A 4YIHA 3U13A 3U19A 2I7DA 3CI0K 1Q5NA 4V2QA 2O7EA 1GKMA 1FUOA 1GKJA 2PTQA 1U0LA 5EYVA 4BABA 2NYFA
chains in the Genus database with same CATH topology
1JSWA 5EYTA 2E9FA 5F92A 1J3UA 4EEIA 2OHYA 3R6YA 3BHGA 5D6BA 2FUSA 3NZ4A 1U15A 2YIIA 1W27A 3R6VA 4FLCA 1FURA 3R6QA 1EB4A 3OCEA 4BAAA 1XWOA 2VD6A 4C5SA 3QBPA 4V2RA 1C3CA 1TJUA 2HVGA 5F91A 1DOFA 4CQ5A 4C5RA 1RE5A 5HW2A 3KDYA 1Y2MA 1YFEA 4C6GA 2PTSA 1FUPA 4ADLA 1YFMA 2PFMA 3TV2A 1K62A 1TJWA 1C3UA 2J91A 4EFCA 1KQ7A 1TJ7A 2X75A 4C5UA 1YISA 2O7BA 1DCNA 2O6YA 4NLEA 3OCFA 3RD8A 1GK3A 2O7FA 3NO9A 1FUQA 2NYNA 1TJVA 4ADMA 2O7DA 2PTRA 1HY1A 3CZOA 4NSLA 1HY0A 1GK2A 3RRPA 2QVEA 1AUWA 1T6PA 1U16A 4APBA 2O78A 4HGVA 4APAA 2RJRA 1B8FA 1I0AA 2RJSA 2QGAB 1K7WA 3UNVA 4FFXA 1VDKA 3KDZA 3GZHA 3C8TA 3GTDA 1T6JA 3E04A 4MX2A 1Q5NA 4V2QA 2O7EA 1GKMA 1FUOA 1GKJA 2PTQA 5EYVA 4BABA 2NYFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JSW A;  5EYT A;  2E9F A;  5F92 A;  1J3U A;  4EEI A;  2OHY A;  3R6Y A;  3BHG A;  5D6B A;  2FUS A;  3NZ4 A;  1U15 A;  2YII A;  1W27 A;  3R6V A;  4FLC A;  1FUR A;  3R6Q A;  1EB4 A;  3OCE A;  4BAA A;  1XWO A;  2VD6 A;  4C5S A;  3QBP A;  4V2R A;  1C3C A;  1TJU A;  2HVG A;  5F91 A;  1DOF A;  4CQ5 A;  4C5R A;  1RE5 A;  5HW2 A;  3KDY A;  1Y2M A;  1YFE A;  4C6G A;  2PTS A;  1FUP A;  4ADL A;  1YFM A;  2PFM A;  3TV2 A;  1K62 A;  1TJW A;  1C3U A;  2J91 A;  4EFC A;  1KQ7 A;  1TJ7 A;  2X75 A;  4C5U A;  1YIS A;  2O7B A;  1DCN A;  2O6Y A;  4NLE A;  3OCF A;  3RD8 A;  1GK3 A;  2O7F A;  3NO9 A;  1FUQ A;  2NYN A;  1TJV A;  4ADM A;  2O7D A;  2PTR A;  1HY1 A;  3CZO A;  4NSL A;  1HY0 A;  1GK2 A;  3RRP A;  2QVE A;  1AUW A;  1T6P A;  1U16 A;  4APB A;  2O78 A;  4HGV A;  4APA A;  2RJR A;  1B8F A;  1I0A A;  2RJS A;  2QGA B;  1K7W A;  3UNV A;  4FFX A;  1VDK A;  3KDZ A;  3GZH A;  3C8T A;  3GTD A;  1T6J A;  3E04 A;  4MX2 A;  1Q5N A;  4V2Q A;  2O7E A;  1GKM A;  1FUO A;  1GKJ A;  2PTQ A;  5EYV A;  4BAB A;  2NYF A; 
#chains in the Genus database with same CATH topology
 1JSW A;  2FEN A;  5EYT A;  2E9F A;  5F92 A;  1J3U A;  4EEI A;  5H8W A;  2OHY A;  3R6Y A;  3F4S A;  4A15 A;  3F4R A;  3BHG A;  3CRV A;  5D6B A;  1Z4M A;  2FUS A;  3NZ4 A;  1U15 A;  2YII A;  1W27 A;  3R6V A;  4FLC A;  1FUR A;  3R6Q A;  1EB4 A;  3OCE A;  4BAA A;  1XWO A;  1Z4K A;  2D28 C;  2VD6 A;  4C5S A;  1IW7 D;  3QBP A;  4V2R A;  2JAW A;  1C3C A;  2JAR A;  1XL8 A;  1TJU A;  2HVG A;  5F91 A;  1DOF A;  4CQ5 A;  2VL7 A;  1T9H A;  4C5R A;  1RE5 A;  5HW2 A;  3KDY A;  1Y2M A;  1YFE A;  4C6G A;  4WNL A;  2PTS A;  1FUP A;  4ADL A;  1YFM A;  2PFM A;  3F4T A;  3TV2 A;  1K62 A;  1Z4P X;  1TJW A;  2YV5 A;  1C3U A;  2J91 A;  4NFL A;  4EFC A;  1KQ7 A;  1TJ7 A;  2X75 A;  4C5U A;  1YIS A;  2O7B A;  1DCN A;  2O6Y A;  2RCN A;  4L6C A;  1XL7 A;  4NLE A;  2VSF A;  3OCF A;  3RD8 A;  1GK3 A;  2O7F A;  3NO9 A;  1Q91 A;  4MUM A;  1FUQ A;  2NYN A;  1TJV A;  4ADM A;  4IQJ M;  5M0I A;  2O7D A;  2PTR A;  1XLY A;  1HY1 A;  4E88 A;  3CZO A;  1XMD A;  4NSL A;  2FEL A;  2D27 A;  1HY0 A;  3BWV A;  1GK2 A;  4MWO A;  3RRP A;  2QVE A;  1AUW A;  1Z4Q A;  1T6P A;  1U16 A;  4APB A;  2O78 A;  4HGV A;  1MH9 A;  3CRW 1;  5M0J A;  2JAU A;  4APA A;  2RJR A;  1Z4L A;  1B8F A;  1I0A A;  1Z4I A;  2RJS A;  1Z4J A;  2QGA B;  4L57 A;  1K7W A;  3UNV A;  2JAO A;  4FFX A;  1Q92 A;  1VDK A;  4L6A A;  3KDZ A;  3GZH A;  4YIK A;  3C8T A;  3GTD A;  1T6J A;  1XMC A;  3E04 A;  4MX2 A;  4YIH A;  3U13 A;  3U19 A;  2I7D A;  3CI0 K;  1Q5N A;  4V2Q A;  2O7E A;  1GKM A;  1FUO A;  1GKJ A;  2PTQ A;  1U0L A;  5EYV A;  4BAB A;  2NYF A; 
#chains in the Genus database with same CATH homology
 1JSW A;  5EYT A;  2E9F A;  5F92 A;  1J3U A;  4EEI A;  2OHY A;  3R6Y A;  3BHG A;  5D6B A;  2FUS A;  3NZ4 A;  1U15 A;  2YII A;  1W27 A;  3R6V A;  4FLC A;  1FUR A;  3R6Q A;  1EB4 A;  3OCE A;  4BAA A;  1XWO A;  2VD6 A;  4C5S A;  3QBP A;  4V2R A;  1C3C A;  1TJU A;  2HVG A;  5F91 A;  1DOF A;  4CQ5 A;  4C5R A;  1RE5 A;  5HW2 A;  3KDY A;  1Y2M A;  1YFE A;  4C6G A;  2PTS A;  1FUP A;  4ADL A;  1YFM A;  2PFM A;  3TV2 A;  1K62 A;  1TJW A;  1C3U A;  2J91 A;  4EFC A;  1KQ7 A;  1TJ7 A;  2X75 A;  4C5U A;  1YIS A;  2O7B A;  1DCN A;  2O6Y A;  4NLE A;  3OCF A;  3RD8 A;  1GK3 A;  2O7F A;  3NO9 A;  1FUQ A;  2NYN A;  1TJV A;  4ADM A;  2O7D A;  2PTR A;  1HY1 A;  3CZO A;  4NSL A;  1HY0 A;  1GK2 A;  3RRP A;  2QVE A;  1AUW A;  1T6P A;  1U16 A;  4APB A;  2O78 A;  4HGV A;  4APA A;  2RJR A;  1B8F A;  1I0A A;  2RJS A;  2QGA B;  1K7W A;  3UNV A;  4FFX A;  1VDK A;  3KDZ A;  3GZH A;  3C8T A;  3GTD A;  1T6J A;  3E04 A;  4MX2 A;  1Q5N A;  4V2Q A;  2O7E A;  1GKM A;  1FUO A;  1GKJ A;  2PTQ A;  5EYV A;  4BAB A;  2NYF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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