4IO9 | Genus

Total Genus 28

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	28
sequence length	175
structure length	175
Chain Sequence	MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Ribosome/ribosome inhibitor
publication title	Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. pubmed doi rcsb
molecule keywords	23S ribosomal RNA
total genus	28
structure length	175
sequence length	175
ec nomenclature
pdb deposition date	2013-01-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
S	PF01386	Ribosomal_L25p	Ribosomal L25p family
S	PF14693	Ribosomal_TL5_C	Ribosomal protein TL5, C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.240.10	Mainly Beta	Beta Barrel	Ribosomal Protein L25; Chain P	Ribosomal Protein L25; Chain P	4io9S01
2.170.120.20	Mainly Beta	Beta Complex	RNA Polymerase Alpha Subunit; Chain A, domain 2	Ribosomal protein L25, beta domain	4io9S02

1QRUA 1O0BA 5JVGS 1GTSA 2ZJRS 2RD2A 1GTRA 5GAEW 2RE8A 1QRTA 2ZJPS 4WCES 5IZNA 1EXDA 1D6KA 4JXXA 1DFUP 4IOCS 4H3SA 3PIOS 5DM6S 2ZJQS 1NYLA 4WFNS 5GAHW 5GADW 4JXZA 3J7ZV 4IO9S 1B75A 5HL7S 5JVHS 2HZ7A 4P2BA 4WF9S 1ZJWA 3CF5S 5BNZA 5DM7S 1O0CA 4WFAS 1QTQA 4UY88 1FEUA 1QRSA 4U67S 3PIPS 5GAGW 4JYZA 4IOAS 1EUYA 1EUQA 4WFBS 3DLLS 3AIIA
chains in the Genus database with same CATH superfamily

2ZJRS 2RD2A 1TWHC 5D4DA 4Y7NC 3GTJC 2YU9C 3DXJA 1QRTA 2ZJPS 5IP9C 3CZBA 1I6VA 1HQMA 2NWAA 3I4NC 2G5DA 3GTMC 5C4XC 2JA6C 4YG2A 3X1LB 5DM6S 5FLMC 1NYLA 1VHYA 5GAHW 5GADW 4JXZA 4C2MC 5IP7C 4G7HA 2NVXC 3EQLA 4A3FC 2B63C 3M3YC 4X6AC 3HOVC 4WF9S 4XLNA 2PI8A 1Z85A 4Q5SA 3W2VB 4JK1A 1QTQA 1VHKA 5TMFA 2E2HC 4A3DC 3KW2A 2EGWA 1TWCC 4A3KC 4QJVA 5GAGW 4JYZA 4IOAS 1EUYA 4MQ9A 2KXYA 1EUQA 4WFBS 4OIPA 4GZYA 3S14C 3PO2C 5JVGS 2NVTC 1GTSA 3RZDC 4Y52C 5GAEW 1YNNA 4OIQA 2RE8A 2BE5A 3GTOC 4QIWD 1SFOC 2EGVA 3M4OC 4XSXA 5HQHA 2E2JC 3S2HC 2KQ1A 2R7ZC 5IYDC 1Y1WC 2PICA 4WFNS 1ZYRA 3HOWC 3WODA 2PJJA 3H0GC 3S1RC 4J3CA 4XSZA 4LLGA 5IYBC 2HZ7A 4A3GC 1Y1VC 1YNJA 4Q4ZA 1IW7A 2PPBA 4BY1C 1K83C 3S1NC 1NXZA 1V6ZA 1O0CA 3K7AC 4UY88 1FEUA 5C4JC 2L3UA 4NOIA 2R93C 1R9TC 2NVYC 4KMUA 1QRUA 4L69A 3W2WB 2A69A 1GTRA 4C3IC 4BBRC 2Z0YA 3S15C 4OIOA 3H3VD 4OINA 2VUMC 3S1QC 1EXDA 4V194 3FKIC 3GTKC 2O5JA 2CX8A 5C44C 4MEXA 3GTPC 4BY7C 1TWFC 2WAQD 2NVQC 3J7ZV 1B75A 1WCMC 4BBSC 4P2BA 4A3MC 2JA7C 4MEYA 2WB1D 3CF5S 1TWGC 5BNZA 4A3JC 4WFAS 2JA5C 3S2DC 2CW0A 4U67S 2A68A 4KN4A 4C3JC 3I4MC 2A6HA 2G6GA 2GAEA 3LYWA 1I6HC 2E2IC 3DLLS 3AIIA 4KN7A 3S1MC 1O0BA 3HOZC 3HOYC 2JA8C 4E8BA 2KPUA 4WCES 1TWAC 5IZNA 3HOXC 3HOUC 1D6KA 4JXXA 2L5NA 1DFUP 2O5IA 5TMCA 4YFKA 4LK0A 4IOCS 4H3SA 3PIOS 1I3QC 4ZH4A 2ZJQS 4LJZA 2R92C 1UDXA 2PNWA 2AE0X 1SMYA 5C3EC 4IO9S 4OIRA 4A3CC 2Y0SD 3GTLC 3S17C 4A3LC 5HL7S 2PA8D 2PMZD 4A3IC 3RZOC 5JVHS 4XLPA 3PO3C 4YFNA 4A3BC 3S16C 3CQZC 1ZJWA 1BDFA 5IYCC 4G7OA 4A93C 5DM7S 4C3HC 4YFXA 1QRSA 4A3EC 3PIPS 4BXXC 3GTQC 1I50C 4G7ZA 4LK1A 2A6EA 4AYBD 3HKZD 4H4KA 3GTGC
chains in the Genus database with same CATH topology

1QRUA 1O0BA 3W2WB 5JVGS 1GTSA 2ZJRS 2RD2A 1GTRA 5GAEW 2RE8A 1QRTA 2ZJPS 4WCES 5IZNA 1EXDA 1D6KA 4V194 4JXXA 1DFUP 4IOCS 4H3SA 3PIOS 3X1LB 5DM6S 2ZJQS 1NYLA 1UDXA 4WFNS 5GAHW 5GADW 4JXZA 3J7ZV 4IO9S 1B75A 5HL7S 5JVHS 2HZ7A 4P2BA 4WF9S 1ZJWA 3CF5S 5BNZA 3W2VB 5DM7S 1O0CA 4WFAS 1QTQA 3AIIA 4UY88 1FEUA 1QRSA 4U67S 3PIPS 5GAGW 4JYZA 4IOAS 1EUYA 1EUQA 4WFBS 3DLLS 4H4KA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1QRU A;  1O0B A;  5JVG S;  1GTS A;  2ZJR S;  2RD2 A;  1GTR A;  5GAE W;  2RE8 A;  1QRT A;  2ZJP S;  4WCE S;  5IZN A;  1EXD A;  1D6K A;  4JXX A;  1DFU P;  4IOC S;  4H3S A;  3PIO S;  5DM6 S;  2ZJQ S;  1NYL A;  4WFN S;  5GAH W;  5GAD W;  4JXZ A;  3J7Z V;  4IO9 S;  1B75 A;  5HL7 S;  5JVH S;  2HZ7 A;  4P2B A;  4WF9 S;  1ZJW A;  3CF5 S;  5BNZ A;  5DM7 S;  1O0C A;  4WFA S;  1QTQ A;  4UY8 8;  1FEU A;  1QRS A;  4U67 S;  3PIP S;  5GAG W;  4JYZ A;  4IOA S;  1EUY A;  1EUQ A;  4WFB S;  3DLL S;  3AII A; 
#chains in the Genus database with same CATH topology
 2ZJR S;  2RD2 A;  1TWH C;  5D4D A;  4Y7N C;  3GTJ C;  2YU9 C;  3DXJ A;  1QRT A;  2ZJP S;  5IP9 C;  3CZB A;  1I6V A;  1HQM A;  2NWA A;  3I4N C;  2G5D A;  3GTM C;  5C4X C;  2JA6 C;  4YG2 A;  3X1L B;  5DM6 S;  5FLM C;  1NYL A;  1VHY A;  5GAH W;  5GAD W;  4JXZ A;  4C2M C;  5IP7 C;  4G7H A;  2NVX C;  3EQL A;  4A3F C;  2B63 C;  3M3Y C;  4X6A C;  3HOV C;  4WF9 S;  4XLN A;  2PI8 A;  1Z85 A;  4Q5S A;  3W2V B;  4JK1 A;  1QTQ A;  1VHK A;  5TMF A;  2E2H C;  4A3D C;  3KW2 A;  2EGW A;  1TWC C;  4A3K C;  4QJV A;  5GAG W;  4JYZ A;  4IOA S;  1EUY A;  4MQ9 A;  2KXY A;  1EUQ A;  4WFB S;  4OIP A;  4GZY A;  3S14 C;  3PO2 C;  5JVG S;  2NVT C;  1GTS A;  3RZD C;  4Y52 C;  5GAE W;  1YNN A;  4OIQ A;  2RE8 A;  2BE5 A;  3GTO C;  4QIW D;  1SFO C;  2EGV A;  3M4O C;  4XSX A;  5HQH A;  2E2J C;  3S2H C;  2KQ1 A;  2R7Z C;  5IYD C;  1Y1W C;  2PIC A;  4WFN S;  1ZYR A;  3HOW C;  3WOD A;  2PJJ A;  3H0G C;  3S1R C;  4J3C A;  4XSZ A;  4LLG A;  5IYB C;  2HZ7 A;  4A3G C;  1Y1V C;  1YNJ A;  4Q4Z A;  1IW7 A;  2PPB A;  4BY1 C;  1K83 C;  3S1N C;  1NXZ A;  1V6Z A;  1O0C A;  3K7A C;  4UY8 8;  1FEU A;  5C4J C;  2L3U A;  4NOI A;  2R93 C;  1R9T C;  2NVY C;  4KMU A;  1QRU A;  4L69 A;  3W2W B;  2A69 A;  1GTR A;  4C3I C;  4BBR C;  2Z0Y A;  3S15 C;  4OIO A;  3H3V D;  4OIN A;  2VUM C;  3S1Q C;  1EXD A;  4V19 4;  3FKI C;  3GTK C;  2O5J A;  2CX8 A;  5C44 C;  4MEX A;  3GTP C;  4BY7 C;  1TWF C;  2WAQ D;  2NVQ C;  3J7Z V;  1B75 A;  1WCM C;  4BBS C;  4P2B A;  4A3M C;  2JA7 C;  4MEY A;  2WB1 D;  3CF5 S;  1TWG C;  5BNZ A;  4A3J C;  4WFA S;  2JA5 C;  3S2D C;  2CW0 A;  4U67 S;  2A68 A;  4KN4 A;  4C3J C;  3I4M C;  2A6H A;  2G6G A;  2GAE A;  3LYW A;  1I6H C;  2E2I C;  3DLL S;  3AII A;  4KN7 A;  3S1M C;  1O0B A;  3HOZ C;  3HOY C;  2JA8 C;  4E8B A;  2KPU A;  4WCE S;  1TWA C;  5IZN A;  3HOX C;  3HOU C;  1D6K A;  4JXX A;  2L5N A;  1DFU P;  2O5I A;  5TMC A;  4YFK A;  4LK0 A;  4IOC S;  4H3S A;  3PIO S;  1I3Q C;  4ZH4 A;  2ZJQ S;  4LJZ A;  2R92 C;  1UDX A;  2PNW A;  2AE0 X;  1SMY A;  5C3E C;  4IO9 S;  4OIR A;  4A3C C;  2Y0S D;  3GTL C;  3S17 C;  4A3L C;  5HL7 S;  2PA8 D;  2PMZ D;  4A3I C;  3RZO C;  5JVH S;  4XLP A;  3PO3 C;  4YFN A;  4A3B C;  3S16 C;  3CQZ C;  1ZJW A;  1BDF A;  5IYC C;  4G7O A;  4A93 C;  5DM7 S;  4C3H C;  4YFX A;  1QRS A;  4A3E C;  3PIP S;  4BXX C;  3GTQ C;  1I50 C;  4G7Z A;  4LK1 A;  2A6E A;  4AYB D;  3HKZ D;  4H4K A;  3GTG C; 
#chains in the Genus database with same CATH homology
 1QRU A;  1O0B A;  3W2W B;  5JVG S;  1GTS A;  2ZJR S;  2RD2 A;  1GTR A;  5GAE W;  2RE8 A;  1QRT A;  2ZJP S;  4WCE S;  5IZN A;  1EXD A;  1D6K A;  4V19 4;  4JXX A;  1DFU P;  4IOC S;  4H3S A;  3PIO S;  3X1L B;  5DM6 S;  2ZJQ S;  1NYL A;  1UDX A;  4WFN S;  5GAH W;  5GAD W;  4JXZ A;  3J7Z V;  4IO9 S;  1B75 A;  5HL7 S;  5JVH S;  2HZ7 A;  4P2B A;  4WF9 S;  1ZJW A;  3CF5 S;  5BNZ A;  3W2V B;  5DM7 S;  1O0C A;  4WFA S;  1QTQ A;  3AII A;  4UY8 8;  1FEU A;  1QRS A;  4U67 S;  3PIP S;  5GAG W;  4JYZ A;  4IOA S;  1EUY A;  1EUQ A;  4WFB S;  3DLL S;  4H4K A;

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similar chains in the Genus database (?% sequence similarity)

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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4IO9S

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations