4WF9S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with telithromycin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 24
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wf9S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wf9S02
1GTSA 1QRTA 1DFUP 4WFNS 3J7ZV 5DM7S 5JVHS 4JYZA 5GAEW 4P2BA 1O0BA 2ZJRS 5JVGS 4IO9S 4WFBS 5BNZA 4JXXA 1GTRA 1FEUA 4WFAS 2RE8A 4U67S 1QRUA 4WF9S 1O0CA 4IOAS 4H3SA 5GAHW 2RD2A 3AIIA 1B75A 4WCES 5GAGW 2ZJPS 4UY88 5GADW 5DM6S 3PIOS 2HZ7A 1EUQA 5HL7S 1D6KA 3CF5S 4IOCS 5IZNA 4JXZA 1EXDA 3PIPS 2ZJQS 1QTQA 1EUYA 1QRSA 3DLLS 1NYLA 1ZJWA
chains in the Genus database with same CATH superfamily
3M4OC 1GTSA 4KN7A 3K7AC 4BY1C 4A3LC 4JYZA 5FLMC 2PI8A 2ZJRS 5JVGS 3HOXC 4JXXA 1GTRA 1FEUA 1Y1WC 3S2DC 4A3EC 1ZYRA 2L3UA 4C3JC 1O0CA 3LYWA 2CX8A 4MQ9A 4H3SA 2PMZD 4AYBD 5IP7C 3S1RC 2R7ZC 3AIIA 1TWGC 2KXYA 5GAGW 4LLGA 3CQZC 2JA6C 4MEYA 3S16C 1D6KA 5C44C 4A3KC 1NXZA 2Y0SD 3PIPS 2A6HA 5IYCC 2PJJA 4KN4A 4QJVA 2JA5C 2NVQC 4C2MC 3RZOC 1QRSA 4IO9S 3CF5S 3DLLS 3W2WB 2VUMC 1BDFA 1DFUP 2A6EA 2L5NA 3GTOC 3J7ZV 4KMUA 2NVTC 1Y1VC 1TWHC 1TWAC 2NVYC 1O0BA 2CW0A 4Y7NC 2PICA 1I6VA 4WFAS 4C3HC 3GTPC 1K83C 3S1MC 2E2IC 4U67S 4WF9S 4ZH4A 2PPBA 3GTLC 1YNJA 1B75A 2EGVA 5C4XC 4NOIA 1SMYA 2B63C 2O5IA 4BY7C 2JA8C 1WCMC 3H0GC 4YFXA 2G5DA 5HL7S 4C3IC 4JK1A 2O5JA 3S1NC 3GTQC 5IZNA 2WAQD 2ZJQS 3I4NC 4A3GC 3HOZC 3S15C 4OIOA 3EQLA 1EUYA 4J3CA 1HQMA 1NYLA 4LK0A 4E8BA 4BBSC 3S14C 2JA7C 4WFNS 5DM7S 4G7OA 1I6HC 3HOYC 4XLNA 2R92C 3S17C 4YG2A 2GAEA 2Z0YA 4LK1A 5HQHA 2NVXC 1IW7A 1YNNA 3S2HC 4IOAS 2RD2A 4OINA 1V6ZA 4L69A 5D4DA 4WCES 5TMFA 3GTGC 2ZJPS 3HKZD 2BE5A 4Y52C 1TWCC 2KQ1A 4G7ZA 3GTMC 4A3IC 3HOUC 3PO2C 2PNWA 3CZBA 3S1QC 4BXXC 4A93C 5IYBC 1Z85A 3RZDC 4OIRA 2AE0X 4IOCS 4X6AC 4Q4ZA 3H3VD 4JXZA 3GTJC 2A68A 1EXDA 3PO3C 4H4KA 2PA8D 4XSXA 1QTQA 4GZYA 4XLPA 3X1LB 4OIPA 2YU9C 4UY88 3WODA 1ZJWA 1R9TC 1QRTA 5IP9C 2KPUA 3DXJA 5TMCA 3FKIC 5JVHS 1UDXA 5C4JC 5GAEW 4LJZA 4P2BA 4YFNA 2E2JC 3HOWC 3M3YC 4WFBS 5BNZA 1I3QC 2E2HC 2RE8A 4A3CC 2WB1D 4OIQA 1QRUA 4XSZA 5GAHW 4BBRC 4A3JC 4A3DC 4V194 3KW2A 5GADW 3W2VB 4G7HA 5DM6S 3PIOS 2HZ7A 1VHKA 1EUQA 1I50C 3GTKC 2R93C 5C3EC 4A3FC 4A3MC 2G6GA 5IYDC 1TWFC 3HOVC 4QIWD 3I4MC 1VHYA 4MEXA 2EGWA 2A69A 4YFKA 4Q5SA 2NWAA 4A3BC 1SFOC
chains in the Genus database with same CATH topology
1GTSA 1QRTA 1DFUP 4WFNS 3J7ZV 5DM7S 5JVHS 1UDXA 4JYZA 5GAEW 4P2BA 1O0BA 2ZJRS 5JVGS 4IO9S 4WFBS 5BNZA 4JXXA 1GTRA 1FEUA 4WFAS 2RE8A 4U67S 1QRUA 4WF9S 1O0CA 4IOAS 4H3SA 5GAHW 2RD2A 3AIIA 1B75A 4WCES 5GAGW 2ZJPS 4V194 4UY88 5GADW 3W2VB 5DM6S 3PIOS 2HZ7A 1EUQA 5HL7S 1D6KA 3CF5S 4IOCS 5IZNA 4JXZA 1EXDA 3PIPS 4H4KA 2ZJQS 1QTQA 1ZJWA 1EUYA 3X1LB 1QRSA 3DLLS 1NYLA 3W2WB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GTS A;  1QRT A;  1DFU P;  4WFN S;  3J7Z V;  5DM7 S;  5JVH S;  4JYZ A;  5GAE W;  4P2B A;  1O0B A;  2ZJR S;  5JVG S;  4IO9 S;  4WFB S;  5BNZ A;  4JXX A;  1GTR A;  1FEU A;  4WFA S;  2RE8 A;  4U67 S;  1QRU A;  4WF9 S;  1O0C A;  4IOA S;  4H3S A;  5GAH W;  2RD2 A;  3AII A;  1B75 A;  4WCE S;  5GAG W;  2ZJP S;  4UY8 8;  5GAD W;  5DM6 S;  3PIO S;  2HZ7 A;  1EUQ A;  5HL7 S;  1D6K A;  3CF5 S;  4IOC S;  5IZN A;  4JXZ A;  1EXD A;  3PIP S;  2ZJQ S;  1QTQ A;  1EUY A;  1QRS A;  3DLL S;  1NYL A;  1ZJW A; 
#chains in the Genus database with same CATH topology
 3M4O C;  1GTS A;  4KN7 A;  3K7A C;  4BY1 C;  4A3L C;  4JYZ A;  5FLM C;  2PI8 A;  2ZJR S;  5JVG S;  3HOX C;  4JXX A;  1GTR A;  1FEU A;  1Y1W C;  3S2D C;  4A3E C;  1ZYR A;  2L3U A;  4C3J C;  1O0C A;  3LYW A;  2CX8 A;  4MQ9 A;  4H3S A;  2PMZ D;  4AYB D;  5IP7 C;  3S1R C;  2R7Z C;  3AII A;  1TWG C;  2KXY A;  5GAG W;  4LLG A;  3CQZ C;  2JA6 C;  4MEY A;  3S16 C;  1D6K A;  5C44 C;  4A3K C;  1NXZ A;  2Y0S D;  3PIP S;  2A6H A;  5IYC C;  2PJJ A;  4KN4 A;  4QJV A;  2JA5 C;  2NVQ C;  4C2M C;  3RZO C;  1QRS A;  4IO9 S;  3CF5 S;  3DLL S;  3W2W B;  2VUM C;  1BDF A;  1DFU P;  2A6E A;  2L5N A;  3GTO C;  3J7Z V;  4KMU A;  2NVT C;  1Y1V C;  1TWH C;  1TWA C;  2NVY C;  1O0B A;  2CW0 A;  4Y7N C;  2PIC A;  1I6V A;  4WFA S;  4C3H C;  3GTP C;  1K83 C;  3S1M C;  2E2I C;  4U67 S;  4WF9 S;  4ZH4 A;  2PPB A;  3GTL C;  1YNJ A;  1B75 A;  2EGV A;  5C4X C;  4NOI A;  1SMY A;  2B63 C;  2O5I A;  4BY7 C;  2JA8 C;  1WCM C;  3H0G C;  4YFX A;  2G5D A;  5HL7 S;  4C3I C;  4JK1 A;  2O5J A;  3S1N C;  3GTQ C;  5IZN A;  2WAQ D;  2ZJQ S;  3I4N C;  4A3G C;  3HOZ C;  3S15 C;  4OIO A;  3EQL A;  1EUY A;  4J3C A;  1HQM A;  1NYL A;  4LK0 A;  4E8B A;  4BBS C;  3S14 C;  2JA7 C;  4WFN S;  5DM7 S;  4G7O A;  1I6H C;  3HOY C;  4XLN A;  2R92 C;  3S17 C;  4YG2 A;  2GAE A;  2Z0Y A;  4LK1 A;  5HQH A;  2NVX C;  1IW7 A;  1YNN A;  3S2H C;  4IOA S;  2RD2 A;  4OIN A;  1V6Z A;  4L69 A;  5D4D A;  4WCE S;  5TMF A;  3GTG C;  2ZJP S;  3HKZ D;  2BE5 A;  4Y52 C;  1TWC C;  2KQ1 A;  4G7Z A;  3GTM C;  4A3I C;  3HOU C;  3PO2 C;  2PNW A;  3CZB A;  3S1Q C;  4BXX C;  4A93 C;  5IYB C;  1Z85 A;  3RZD C;  4OIR A;  2AE0 X;  4IOC S;  4X6A C;  4Q4Z A;  3H3V D;  4JXZ A;  3GTJ C;  2A68 A;  1EXD A;  3PO3 C;  4H4K A;  2PA8 D;  4XSX A;  1QTQ A;  4GZY A;  4XLP A;  3X1L B;  4OIP A;  2YU9 C;  4UY8 8;  3WOD A;  1ZJW A;  1R9T C;  1QRT A;  5IP9 C;  2KPU A;  3DXJ A;  5TMC A;  3FKI C;  5JVH S;  1UDX A;  5C4J C;  5GAE W;  4LJZ A;  4P2B A;  4YFN A;  2E2J C;  3HOW C;  3M3Y C;  4WFB S;  5BNZ A;  1I3Q C;  2E2H C;  2RE8 A;  4A3C C;  2WB1 D;  4OIQ A;  1QRU A;  4XSZ A;  5GAH W;  4BBR C;  4A3J C;  4A3D C;  4V19 4;  3KW2 A;  5GAD W;  3W2V B;  4G7H A;  5DM6 S;  3PIO S;  2HZ7 A;  1VHK A;  1EUQ A;  1I50 C;  3GTK C;  2R93 C;  5C3E C;  4A3F C;  4A3M C;  2G6G A;  5IYD C;  1TWF C;  3HOV C;  4QIW D;  3I4M C;  1VHY A;  4MEX A;  2EGW A;  2A69 A;  4YFK A;  4Q5S A;  2NWA A;  4A3B C;  1SFO C; 
#chains in the Genus database with same CATH homology
 1GTS A;  1QRT A;  1DFU P;  4WFN S;  3J7Z V;  5DM7 S;  5JVH S;  1UDX A;  4JYZ A;  5GAE W;  4P2B A;  1O0B A;  2ZJR S;  5JVG S;  4IO9 S;  4WFB S;  5BNZ A;  4JXX A;  1GTR A;  1FEU A;  4WFA S;  2RE8 A;  4U67 S;  1QRU A;  4WF9 S;  1O0C A;  4IOA S;  4H3S A;  5GAH W;  2RD2 A;  3AII A;  1B75 A;  4WCE S;  5GAG W;  2ZJP S;  4V19 4;  4UY8 8;  5GAD W;  3W2V B;  5DM6 S;  3PIO S;  2HZ7 A;  1EUQ A;  5HL7 S;  1D6K A;  3CF5 S;  4IOC S;  5IZN A;  4JXZ A;  1EXD A;  3PIP S;  4H4K A;  2ZJQ S;  1QTQ A;  1ZJW A;  1EUY A;  3X1L B;  1QRS A;  3DLL S;  1NYL A;  3W2W B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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