4WFAS

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with linezolid
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S rRNA
total genus 18
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfaS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfaS02
4U67S 1GTRA 4P2BA 2ZJRS 1GTSA 3DLLS 2ZJQS 2RD2A 1EXDA 4IOCS 4WFBS 3AIIA 5GAEW 5JVGS 1EUYA 1B75A 1EUQA 2RE8A 5BNZA 4H3SA 5GADW 5GAHW 4WFAS 1O0BA 5IZNA 1QRUA 1ZJWA 1D6KA 1NYLA 5JVHS 4IOAS 5DM7S 5HL7S 5GAGW 2HZ7A 5DM6S 4UY88 3CF5S 4WCES 4IO9S 1DFUP 1QRTA 3PIPS 3J7ZV 1FEUA 4WF9S 4WFNS 2ZJPS 4JYZA 1O0CA 1QTQA 4JXXA 3PIOS 4JXZA 1QRSA
chains in the Genus database with same CATH superfamily
4Y7NC 4YG2A 4LK1A 2EGVA 3RZDC 4P2BA 1GTSA 4XLNA 4JK1A 4G7HA 2ZJQS 1V6ZA 1SFOC 2E2JC 1TWGC 4BY1C 5GAEW 3RZOC 4QIWD 3GTOC 1VHYA 1EUYA 5C3EC 4OIPA 1EUQA 4Q4ZA 4Y52C 3GTPC 3PO2C 2G5DA 1QRUA 3S14C 1WCMC 2WAQD 5FLMC 4G7OA 4MEXA 5TMCA 3X1LB 1I50C 1I3QC 2EGWA 3GTKC 1FEUA 4WF9S 4A3GC 1NXZA 4WFNS 2ZJPS 1O0CA 4JXXA 2PPBA 3PIOS 4JXZA 4OINA 4BBRC 4XLPA 2JA6C 2L3UA 2KPUA 4C3HC 2WB1D 4KMUA 2ZJRS 4A3MC 2JA5C 3FKIC 1EXDA 4C2MC 2E2IC 2R7ZC 2KQ1A 3S1QC 2O5IA 1B75A 2KXYA 3K7AC 5IP9C 1SMYA 5C4JC 4X6AC 1VHKA 4WFAS 5IZNA 1ZJWA 2A6HA 2VUMC 1D6KA 4IOAS 1TWFC 3S1RC 5TMFA 2A6EA 2PJJA 4ZH4A 4A3IC 4XSXA 3S17C 1TWCC 4QJVA 1HQMA 3I4NC 4H4KA 4JYZA 3CQZC 4A3KC 4A3EC 3HOVC 3HOWC 4BXXC 3S1NC 3H0GC 4U67S 1GTRA 2O5JA 1TWHC 4A3DC 4NOIA 3DLLS 4OIQA 4GZYA 4OIRA 4IOCS 3AIIA 2PMZD 3DXJA 1Y1WC 5HQHA 2RE8A 3PO3C 2G6GA 5BNZA 2PA8D 5IYDC 4H3SA 4L69A 5GADW 5GAHW 4XSZA 3S1MC 4A3CC 1O0BA 2GAEA 4V194 4Q5SA 4E8BA 3S15C 5C4XC 1YNNA 1I6HC 1ZYRA 5HL7S 5GAGW 2HZ7A 3W2VB 2CW0A 4YFNA 4AYBD 5IP7C 3H3VD 2PNWA 3W2WB 1BDFA 1QRTA 4MEYA 5D4DA 3HOUC 3HOXC 3GTGC 3PIPS 2R93C 3J7ZV 4A3FC 3M3YC 3HOYC 2B63C 4OIOA 5C44C 3LYWA 2L5NA 1IW7A 4KN4A 1TWAC 4KN7A 3WODA 5IYCC 4A3BC 2PICA 3KW2A 3GTJC 4LK0A 2BE5A 5IYBC 4A93C 2RD2A 2A68A 3S16C 3S2DC 4WFBS 1R9TC 2JA8C 5JVGS 2R92C 3CZBA 3I4MC 2Z0YA 4BY7C 4BBSC 4A3JC 2NVYC 4LLGA 1UDXA 2Y0SD 3GTMC 2CX8A 2A69A 2NVQC 1Y1VC 1NYLA 5JVHS 4MQ9A 5DM7S 2NVXC 2NWAA 3HKZD 4G7ZA 1K83C 5DM6S 3GTLC 4C3IC 4UY88 3CF5S 4LJZA 4WCES 4IO9S 4C3JC 1DFUP 2NVTC 4J3CA 2PI8A 4YFKA 3M4OC 3EQLA 4A3LC 3HOZC 2YU9C 3GTQC 2E2HC 1Z85A 2AE0X 1QTQA 1I6VA 1YNJA 4YFXA 3S2HC 2JA7C 1QRSA
chains in the Genus database with same CATH topology
4U67S 1GTRA 4P2BA 2ZJRS 1GTSA 3DLLS 2ZJQS 2RD2A 1EXDA 4IOCS 3AIIA 5GAEW 4WFBS 5JVGS 1EUYA 1B75A 1EUQA 2RE8A 5BNZA 4H3SA 5GADW 5GAHW 4WFAS 1UDXA 1O0BA 5IZNA 4V194 1QRUA 1ZJWA 1D6KA 1NYLA 5JVHS 4IOAS 5DM7S 5HL7S 5GAGW 2HZ7A 3W2VB 5DM6S 4UY88 3CF5S 3X1LB 4WCES 4IO9S 1DFUP 3W2WB 1QRTA 3PIPS 3J7ZV 1FEUA 4WF9S 4WFNS 4H4KA 2ZJPS 4JYZA 1O0CA 1QTQA 4JXXA 3PIOS 4JXZA 1QRSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U67 S;  1GTR A;  4P2B A;  2ZJR S;  1GTS A;  3DLL S;  2ZJQ S;  2RD2 A;  1EXD A;  4IOC S;  4WFB S;  3AII A;  5GAE W;  5JVG S;  1EUY A;  1B75 A;  1EUQ A;  2RE8 A;  5BNZ A;  4H3S A;  5GAD W;  5GAH W;  4WFA S;  1O0B A;  5IZN A;  1QRU A;  1ZJW A;  1D6K A;  1NYL A;  5JVH S;  4IOA S;  5DM7 S;  5HL7 S;  5GAG W;  2HZ7 A;  5DM6 S;  4UY8 8;  3CF5 S;  4WCE S;  4IO9 S;  1DFU P;  1QRT A;  3PIP S;  3J7Z V;  1FEU A;  4WF9 S;  4WFN S;  2ZJP S;  4JYZ A;  1O0C A;  1QTQ A;  4JXX A;  3PIO S;  4JXZ A;  1QRS A; 
#chains in the Genus database with same CATH topology
 4Y7N C;  4YG2 A;  4LK1 A;  2EGV A;  3RZD C;  4P2B A;  1GTS A;  4XLN A;  4JK1 A;  4G7H A;  2ZJQ S;  1V6Z A;  1SFO C;  2E2J C;  1TWG C;  4BY1 C;  5GAE W;  3RZO C;  4QIW D;  3GTO C;  1VHY A;  1EUY A;  5C3E C;  4OIP A;  1EUQ A;  4Q4Z A;  4Y52 C;  3GTP C;  3PO2 C;  2G5D A;  1QRU A;  3S14 C;  1WCM C;  2WAQ D;  5FLM C;  4G7O A;  4MEX A;  5TMC A;  3X1L B;  1I50 C;  1I3Q C;  2EGW A;  3GTK C;  1FEU A;  4WF9 S;  4A3G C;  1NXZ A;  4WFN S;  2ZJP S;  1O0C A;  4JXX A;  2PPB A;  3PIO S;  4JXZ A;  4OIN A;  4BBR C;  4XLP A;  2JA6 C;  2L3U A;  2KPU A;  4C3H C;  2WB1 D;  4KMU A;  2ZJR S;  4A3M C;  2JA5 C;  3FKI C;  1EXD A;  4C2M C;  2E2I C;  2R7Z C;  2KQ1 A;  3S1Q C;  2O5I A;  1B75 A;  2KXY A;  3K7A C;  5IP9 C;  1SMY A;  5C4J C;  4X6A C;  1VHK A;  4WFA S;  5IZN A;  1ZJW A;  2A6H A;  2VUM C;  1D6K A;  4IOA S;  1TWF C;  3S1R C;  5TMF A;  2A6E A;  2PJJ A;  4ZH4 A;  4A3I C;  4XSX A;  3S17 C;  1TWC C;  4QJV A;  1HQM A;  3I4N C;  4H4K A;  4JYZ A;  3CQZ C;  4A3K C;  4A3E C;  3HOV C;  3HOW C;  4BXX C;  3S1N C;  3H0G C;  4U67 S;  1GTR A;  2O5J A;  1TWH C;  4A3D C;  4NOI A;  3DLL S;  4OIQ A;  4GZY A;  4OIR A;  4IOC S;  3AII A;  2PMZ D;  3DXJ A;  1Y1W C;  5HQH A;  2RE8 A;  3PO3 C;  2G6G A;  5BNZ A;  2PA8 D;  5IYD C;  4H3S A;  4L69 A;  5GAD W;  5GAH W;  4XSZ A;  3S1M C;  4A3C C;  1O0B A;  2GAE A;  4V19 4;  4Q5S A;  4E8B A;  3S15 C;  5C4X C;  1YNN A;  1I6H C;  1ZYR A;  5HL7 S;  5GAG W;  2HZ7 A;  3W2V B;  2CW0 A;  4YFN A;  4AYB D;  5IP7 C;  3H3V D;  2PNW A;  3W2W B;  1BDF A;  1QRT A;  4MEY A;  5D4D A;  3HOU C;  3HOX C;  3GTG C;  3PIP S;  2R93 C;  3J7Z V;  4A3F C;  3M3Y C;  3HOY C;  2B63 C;  4OIO A;  5C44 C;  3LYW A;  2L5N A;  1IW7 A;  4KN4 A;  1TWA C;  4KN7 A;  3WOD A;  5IYC C;  4A3B C;  2PIC A;  3KW2 A;  3GTJ C;  4LK0 A;  2BE5 A;  5IYB C;  4A93 C;  2RD2 A;  2A68 A;  3S16 C;  3S2D C;  4WFB S;  1R9T C;  2JA8 C;  5JVG S;  2R92 C;  3CZB A;  3I4M C;  2Z0Y A;  4BY7 C;  4BBS C;  4A3J C;  2NVY C;  4LLG A;  1UDX A;  2Y0S D;  3GTM C;  2CX8 A;  2A69 A;  2NVQ C;  1Y1V C;  1NYL A;  5JVH S;  4MQ9 A;  5DM7 S;  2NVX C;  2NWA A;  3HKZ D;  4G7Z A;  1K83 C;  5DM6 S;  3GTL C;  4C3I C;  4UY8 8;  3CF5 S;  4LJZ A;  4WCE S;  4IO9 S;  4C3J C;  1DFU P;  2NVT C;  4J3C A;  2PI8 A;  4YFK A;  3M4O C;  3EQL A;  4A3L C;  3HOZ C;  2YU9 C;  3GTQ C;  2E2H C;  1Z85 A;  2AE0 X;  1QTQ A;  1I6V A;  1YNJ A;  4YFX A;  3S2H C;  2JA7 C;  1QRS A; 
#chains in the Genus database with same CATH homology
 4U67 S;  1GTR A;  4P2B A;  2ZJR S;  1GTS A;  3DLL S;  2ZJQ S;  2RD2 A;  1EXD A;  4IOC S;  3AII A;  5GAE W;  4WFB S;  5JVG S;  1EUY A;  1B75 A;  1EUQ A;  2RE8 A;  5BNZ A;  4H3S A;  5GAD W;  5GAH W;  4WFA S;  1UDX A;  1O0B A;  5IZN A;  4V19 4;  1QRU A;  1ZJW A;  1D6K A;  1NYL A;  5JVH S;  4IOA S;  5DM7 S;  5HL7 S;  5GAG W;  2HZ7 A;  3W2V B;  5DM6 S;  4UY8 8;  3CF5 S;  3X1L B;  4WCE S;  4IO9 S;  1DFU P;  3W2W B;  1QRT A;  3PIP S;  3J7Z V;  1FEU A;  4WF9 S;  4WFN S;  4H4K A;  2ZJP S;  4JYZ A;  1O0C A;  1QTQ A;  4JXX A;  3PIO S;  4JXZ A;  1QRS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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