4WFNS

Crystal structure of the large ribosomal subunit (50s) of deinococcus radiodurans containing a three residue insertion in l22 in complex with erythromycin
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 19
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2014-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfnS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfnS02
2ZJPS 1GTSA 2HZ7A 4P2BA 5BNZA 5GADW 4IOCS 4JXXA 1ZJWA 1EUYA 1QRSA 5JVHS 4U67S 4WF9S 1O0BA 1D6KA 1QRUA 2ZJRS 1DFUP 3AIIA 1O0CA 3PIPS 3DLLS 5IZNA 1EXDA 1NYLA 4WFBS 3J7ZV 3PIOS 3CF5S 5DM7S 4UY88 4JYZA 5GAEW 4WFAS 4WFNS 4H3SA 5GAGW 1EUQA 1GTRA 5DM6S 2RD2A 1QTQA 1QRTA 5HL7S 4IO9S 4WCES 2ZJQS 4IOAS 4JXZA 1FEUA 1B75A 5GAHW 5JVGS 2RE8A
chains in the Genus database with same CATH superfamily
2ZJPS 1Y1VC 2NVQC 3HOUC 3S2HC 4X6AC 3KW2A 4P2BA 5HQHA 4OIQA 2JA8C 3I4MC 4OIPA 2A69A 1Y1WC 4A93C 2EGVA 2PPBA 1TWHC 1QRUA 3HOZC 2ZJRS 1DFUP 3WODA 4A3CC 5IYCC 2A6HA 3X1LB 3EQLA 2NVTC 4MEXA 3DXJA 4LK1A 1NYLA 4WFBS 1TWAC 5DM7S 2AE0X 4XLNA 5IP7C 2E2HC 1EUQA 5IYBC 4OINA 3S2DC 4A3LC 2O5IA 4XSZA 1QTQA 3HOYC 2NVYC 3GTQC 4IO9S 2VUMC 4E8BA 5IYDC 2Z0YA 1B75A 5GAHW 2R93C 1WCMC 2KQ1A 2NWAA 2RE8A 2PJJA 1GTSA 4XLPA 3S1RC 2NVXC 2HZ7A 3GTKC 3M4OC 5GADW 5TMFA 1VHKA 4IOCS 2G6GA 4JXXA 3RZDC 2R7ZC 3S14C 3M3YC 3HKZD 3K7AC 2L3UA 3S16C 4BY7C 1Z85A 1TWGC 3LYWA 4V194 2JA5C 4BXXC 1I6HC 2GAEA 3DLLS 4LK0A 5IZNA 4LLGA 4C2MC 3S1MC 1I6VA 1HQMA 5C4JC 2PI8A 4UY88 4JYZA 5GAEW 4WFAS 4BY1C 2KXYA 2R92C 3GTOC 4YFKA 3GTLC 4GZYA 3H3VD 2RD2A 4C3IC 4A3FC 2PA8D 4Y52C 4BBRC 1IW7A 1QRTA 4JXZA 2ZJQS 2KPUA 5C44C 2WB1D 3CZBA 2JA7C 3S1NC 3CQZC 3PO2C 1I50C 4QIWD 4LJZA 4YG2A 1K83C 1QRSA 4A3DC 5JVHS 2O5JA 4J3CA 4U67S 4KMUA 1D6KA 3RZOC 2PICA 3S1QC 2B63C 2Y0SD 3I4NC 4XSXA 3GTGC 3AIIA 4KN4A 1YNJA 3FKIC 2WAQD 3PIOS 1SMYA 2CW0A 4Y7NC 4G7ZA 4YFXA 3GTMC 1I3QC 5GAGW 1GTRA 3W2VB 5DM6S 1YNNA 4MEYA 1V6ZA 4IOAS 2EGWA 4WCES 4L69A 2A68A 2CX8A 4Q5SA 2G5DA 5JVGS 4OIRA 4ZH4A 3GTPC 3PO3C 5BNZA 1UDXA 3W2WB 1R9TC 3GTJC 1ZJWA 4QJVA 1EUYA 2PMZD 4JK1A 5C3EC 4Q4ZA 3S15C 4A3IC 2PNWA 4A3BC 4KN7A 2E2JC 4A3GC 4WF9S 1O0BA 4A3MC 2JA6C 1TWFC 4C3HC 3H0GC 1BDFA 5FLMC 1O0CA 4A3JC 3PIPS 2BE5A 3HOVC 1EXDA 4MQ9A 4BBSC 3J7ZV 4G7OA 3CF5S 1ZYRA 4YFNA 3HOXC 2YU9C 4WFNS 4A3KC 4H3SA 5TMCA 1SFOC 3HOWC 4H4KA 5IP9C 5D4DA 3S17C 4OIOA 2A6EA 1VHYA 5HL7S 4AYBD 4A3EC 2E2IC 1FEUA 5C4XC 1NXZA 2L5NA 4G7HA 1TWCC 4C3JC 4NOIA
chains in the Genus database with same CATH topology
2ZJPS 1GTSA 2HZ7A 4P2BA 5BNZA 5GADW 1UDXA 3W2WB 4IOCS 4JXXA 1ZJWA 1EUYA 1QRSA 5JVHS 4U67S 4WF9S 1O0BA 1D6KA 4V194 1QRUA 2ZJRS 1DFUP 3X1LB 3AIIA 1O0CA 3PIPS 3DLLS 5IZNA 1EXDA 1NYLA 4WFBS 3J7ZV 3PIOS 3CF5S 5DM7S 4UY88 4JYZA 5GAEW 4WFAS 4WFNS 4H3SA 5GAGW 1EUQA 1GTRA 3W2VB 4H4KA 5DM6S 2RD2A 1QTQA 1QRTA 5HL7S 4IO9S 4WCES 2ZJQS 4IOAS 4JXZA 1FEUA 1B75A 5GAHW 5JVGS 2RE8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJP S;  1GTS A;  2HZ7 A;  4P2B A;  5BNZ A;  5GAD W;  4IOC S;  4JXX A;  1ZJW A;  1EUY A;  1QRS A;  5JVH S;  4U67 S;  4WF9 S;  1O0B A;  1D6K A;  1QRU A;  2ZJR S;  1DFU P;  3AII A;  1O0C A;  3PIP S;  3DLL S;  5IZN A;  1EXD A;  1NYL A;  4WFB S;  3J7Z V;  3PIO S;  3CF5 S;  5DM7 S;  4UY8 8;  4JYZ A;  5GAE W;  4WFA S;  4WFN S;  4H3S A;  5GAG W;  1EUQ A;  1GTR A;  5DM6 S;  2RD2 A;  1QTQ A;  1QRT A;  5HL7 S;  4IO9 S;  4WCE S;  2ZJQ S;  4IOA S;  4JXZ A;  1FEU A;  1B75 A;  5GAH W;  5JVG S;  2RE8 A; 
#chains in the Genus database with same CATH topology
 2ZJP S;  1Y1V C;  2NVQ C;  3HOU C;  3S2H C;  4X6A C;  3KW2 A;  4P2B A;  5HQH A;  4OIQ A;  2JA8 C;  3I4M C;  4OIP A;  2A69 A;  1Y1W C;  4A93 C;  2EGV A;  2PPB A;  1TWH C;  1QRU A;  3HOZ C;  2ZJR S;  1DFU P;  3WOD A;  4A3C C;  5IYC C;  2A6H A;  3X1L B;  3EQL A;  2NVT C;  4MEX A;  3DXJ A;  4LK1 A;  1NYL A;  4WFB S;  1TWA C;  5DM7 S;  2AE0 X;  4XLN A;  5IP7 C;  2E2H C;  1EUQ A;  5IYB C;  4OIN A;  3S2D C;  4A3L C;  2O5I A;  4XSZ A;  1QTQ A;  3HOY C;  2NVY C;  3GTQ C;  4IO9 S;  2VUM C;  4E8B A;  5IYD C;  2Z0Y A;  1B75 A;  5GAH W;  2R93 C;  1WCM C;  2KQ1 A;  2NWA A;  2RE8 A;  2PJJ A;  1GTS A;  4XLP A;  3S1R C;  2NVX C;  2HZ7 A;  3GTK C;  3M4O C;  5GAD W;  5TMF A;  1VHK A;  4IOC S;  2G6G A;  4JXX A;  3RZD C;  2R7Z C;  3S14 C;  3M3Y C;  3HKZ D;  3K7A C;  2L3U A;  3S16 C;  4BY7 C;  1Z85 A;  1TWG C;  3LYW A;  4V19 4;  2JA5 C;  4BXX C;  1I6H C;  2GAE A;  3DLL S;  4LK0 A;  5IZN A;  4LLG A;  4C2M C;  3S1M C;  1I6V A;  1HQM A;  5C4J C;  2PI8 A;  4UY8 8;  4JYZ A;  5GAE W;  4WFA S;  4BY1 C;  2KXY A;  2R92 C;  3GTO C;  4YFK A;  3GTL C;  4GZY A;  3H3V D;  2RD2 A;  4C3I C;  4A3F C;  2PA8 D;  4Y52 C;  4BBR C;  1IW7 A;  1QRT A;  4JXZ A;  2ZJQ S;  2KPU A;  5C44 C;  2WB1 D;  3CZB A;  2JA7 C;  3S1N C;  3CQZ C;  3PO2 C;  1I50 C;  4QIW D;  4LJZ A;  4YG2 A;  1K83 C;  1QRS A;  4A3D C;  5JVH S;  2O5J A;  4J3C A;  4U67 S;  4KMU A;  1D6K A;  3RZO C;  2PIC A;  3S1Q C;  2B63 C;  2Y0S D;  3I4N C;  4XSX A;  3GTG C;  3AII A;  4KN4 A;  1YNJ A;  3FKI C;  2WAQ D;  3PIO S;  1SMY A;  2CW0 A;  4Y7N C;  4G7Z A;  4YFX A;  3GTM C;  1I3Q C;  5GAG W;  1GTR A;  3W2V B;  5DM6 S;  1YNN A;  4MEY A;  1V6Z A;  4IOA S;  2EGW A;  4WCE S;  4L69 A;  2A68 A;  2CX8 A;  4Q5S A;  2G5D A;  5JVG S;  4OIR A;  4ZH4 A;  3GTP C;  3PO3 C;  5BNZ A;  1UDX A;  3W2W B;  1R9T C;  3GTJ C;  1ZJW A;  4QJV A;  1EUY A;  2PMZ D;  4JK1 A;  5C3E C;  4Q4Z A;  3S15 C;  4A3I C;  2PNW A;  4A3B C;  4KN7 A;  2E2J C;  4A3G C;  4WF9 S;  1O0B A;  4A3M C;  2JA6 C;  1TWF C;  4C3H C;  3H0G C;  1BDF A;  5FLM C;  1O0C A;  4A3J C;  3PIP S;  2BE5 A;  3HOV C;  1EXD A;  4MQ9 A;  4BBS C;  3J7Z V;  4G7O A;  3CF5 S;  1ZYR A;  4YFN A;  3HOX C;  2YU9 C;  4WFN S;  4A3K C;  4H3S A;  5TMC A;  1SFO C;  3HOW C;  4H4K A;  5IP9 C;  5D4D A;  3S17 C;  4OIO A;  2A6E A;  1VHY A;  5HL7 S;  4AYB D;  4A3E C;  2E2I C;  1FEU A;  5C4X C;  1NXZ A;  2L5N A;  4G7H A;  1TWC C;  4C3J C;  4NOI A; 
#chains in the Genus database with same CATH homology
 2ZJP S;  1GTS A;  2HZ7 A;  4P2B A;  5BNZ A;  5GAD W;  1UDX A;  3W2W B;  4IOC S;  4JXX A;  1ZJW A;  1EUY A;  1QRS A;  5JVH S;  4U67 S;  4WF9 S;  1O0B A;  1D6K A;  4V19 4;  1QRU A;  2ZJR S;  1DFU P;  3X1L B;  3AII A;  1O0C A;  3PIP S;  3DLL S;  5IZN A;  1EXD A;  1NYL A;  4WFB S;  3J7Z V;  3PIO S;  3CF5 S;  5DM7 S;  4UY8 8;  4JYZ A;  5GAE W;  4WFA S;  4WFN S;  4H3S A;  5GAG W;  1EUQ A;  1GTR A;  3W2V B;  4H4K A;  5DM6 S;  2RD2 A;  1QTQ A;  1QRT A;  5HL7 S;  4IO9 S;  4WCE S;  2ZJQ S;  4IOA S;  4JXZ A;  1FEU A;  1B75 A;  5GAH W;  5JVG S;  2RE8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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