4WFNS

Crystal structure of the large ribosomal subunit (50s) of deinococcus radiodurans containing a three residue insertion in l22 in complex with erythromycin
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 19
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2014-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfnS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfnS02
4WFAS 1QRSA 2ZJPS 5GAGW 3DLLS 5BNZA 1O0CA 4WFBS 4IO9S 4IOAS 1GTRA 4P2BA 4H3SA 1EXDA 1ZJWA 1D6KA 2RD2A 1DFUP 1GTSA 4WF9S 5JVGS 1EUQA 5GAEW 3PIPS 4WCES 3J7ZV 5DM6S 4JYZA 5JVHS 1O0BA 4UY88 3PIOS 1QTQA 4U67S 1B75A 1QRTA 2RE8A 2ZJRS 5IZNA 4JXZA 1NYLA 4JXXA 1QRUA 5HL7S 2ZJQS 3CF5S 4IOCS 1EUYA 5GAHW 2HZ7A 1FEUA 5DM7S 4WFNS 3AIIA 5GADW
chains in the Genus database with same CATH superfamily
2GAEA 5IP9C 1VHYA 5GAGW 4E8BA 4Q4ZA 3M4OC 5TMFA 5IYBC 2G6GA 4C2MC 4WFBS 2A68A 4LJZA 4BXXC 4J3CA 2JA5C 4XLPA 2WB1D 5IYCC 4H3SA 3CQZC 5TMCA 2NVTC 3WODA 2E2JC 3FKIC 2RD2A 3S1MC 1GTSA 4XSZA 3S1RC 2L5NA 4Y52C 4JYZA 3S2DC 3LYWA 4GZYA 1Y1WC 2WAQD 1QRTA 3I4NC 3HOUC 2AE0X 2PPBA 3KW2A 4G7ZA 1SMYA 1NYLA 1R9TC 3S1QC 3RZDC 5HL7S 2ZJQS 4KMUA 4IOCS 1EUYA 1FEUA 2HZ7A 5D4DA 4XLNA 4A3FC 1SFOC 4A3CC 2A6HA 2VUMC 1WCMC 1I6HC 4H4KA 3GTMC 2KPUA 3H3VD 4WFAS 4Y7NC 3HKZD 3HOVC 1I3QC 4Q5SA 5C44C 1O0CA 4XSXA 4IO9S 1Y1VC 4A3KC 2BE5A 2NVYC 3S15C 1TWFC 4BY7C 2PJJA 4ZH4A 3GTPC 1YNJA 3GTJC 5HQHA 2PMZD 1TWCC 2PNWA 4G7HA 4A3LC 4MQ9A 4OIPA 4U67S 4KN7A 2RE8A 2R92C 4A3IC 3HOYC 1IW7A 3W2VB 3I4MC 4A3BC 3HOXC 4A93C 4AYBD 4LLGA 4LK0A 4OINA 1TWAC 1V6ZA 1BDFA 3S16C 1QRSA 2ZJPS 5IYDC 2JA7C 4JK1A 4A3MC 4C3JC 2PA8D 5FLMC 3S2HC 3GTKC 2JA8C 1GTRA 2NWAA 1I6VA 4A3JC 4C3HC 3S17C 1ZJWA 2PI8A 1D6KA 1TWHC 3HOWC 4X6AC 4MEXA 4KN4A 1EUQA 2R7ZC 4WCES 3J7ZV 1HQMA 4UY88 5JVHS 4C3IC 3RZOC 4YFXA 5C4XC 3X1LB 4OIQA 4YG2A 3GTGC 4V194 2E2HC 5IZNA 4BBRC 1K83C 3W2WB 4JXXA 2Z0YA 4LK1A 4A3EC 3S1NC 4A3DC 1YNNA 3HOZC 3CF5S 2E2IC 2B63C 2A69A 5GAHW 2L3UA 2CX8A 3H0GC 2O5JA 1DFUP 4NOIA 5GADW 2KQ1A 2R93C 2EGVA 1ZYRA 3M3YC 1TWGC 3DLLS 5BNZA 2NVQC 4YFKA 2EGWA 4IOAS 4OIOA 3GTOC 3DXJA 2PICA 1NXZA 4OIRA 5C4JC 4P2BA 3GTLC 3PO3C 4G7OA 1VHKA 1EXDA 2NVXC 1Z85A 4MEYA 4L69A 4QJVA 5C3EC 4WF9S 4BY1C 2JA6C 5JVGS 3S14C 3GTQC 1UDXA 5GAEW 2G5DA 3PIPS 5IP7C 5DM6S 4BBSC 4A3GC 1O0BA 2CW0A 3K7AC 3PIOS 1QTQA 1B75A 2YU9C 3PO2C 2ZJRS 2A6EA 2KXYA 4QIWD 4JXZA 1QRUA 2Y0SD 3CZBA 3EQLA 4YFNA 2O5IA 1I50C 5DM7S 4WFNS 3AIIA
chains in the Genus database with same CATH topology
4H4KA 4WFAS 1QRSA 2ZJPS 5GAGW 3DLLS 5BNZA 1O0CA 4WFBS 4IO9S 4IOAS 1GTRA 4H3SA 4P2BA 1EXDA 1ZJWA 1D6KA 2RD2A 1DFUP 1GTSA 4WF9S 5JVGS 1UDXA 5GAEW 1EUQA 3PIPS 4WCES 3J7ZV 5DM6S 4JYZA 5JVHS 1O0BA 4UY88 3X1LB 3PIOS 1QTQA 4U67S 4V194 1QRTA 2RE8A 1B75A 2ZJRS 5IZNA 3W2VB 4JXZA 1NYLA 3W2WB 4JXXA 1QRUA 5HL7S 2ZJQS 3CF5S 4IOCS 1EUYA 5GAHW 2HZ7A 1FEUA 5DM7S 4WFNS 3AIIA 5GADW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFA S;  1QRS A;  2ZJP S;  5GAG W;  3DLL S;  5BNZ A;  1O0C A;  4WFB S;  4IO9 S;  4IOA S;  1GTR A;  4P2B A;  4H3S A;  1EXD A;  1ZJW A;  1D6K A;  2RD2 A;  1DFU P;  1GTS A;  4WF9 S;  5JVG S;  1EUQ A;  5GAE W;  3PIP S;  4WCE S;  3J7Z V;  5DM6 S;  4JYZ A;  5JVH S;  1O0B A;  4UY8 8;  3PIO S;  1QTQ A;  4U67 S;  1B75 A;  1QRT A;  2RE8 A;  2ZJR S;  5IZN A;  4JXZ A;  1NYL A;  4JXX A;  1QRU A;  5HL7 S;  2ZJQ S;  3CF5 S;  4IOC S;  1EUY A;  5GAH W;  2HZ7 A;  1FEU A;  5DM7 S;  4WFN S;  3AII A;  5GAD W; 
#chains in the Genus database with same CATH topology
 2GAE A;  5IP9 C;  1VHY A;  5GAG W;  4E8B A;  4Q4Z A;  3M4O C;  5TMF A;  5IYB C;  2G6G A;  4C2M C;  4WFB S;  2A68 A;  4LJZ A;  4BXX C;  4J3C A;  2JA5 C;  4XLP A;  2WB1 D;  5IYC C;  4H3S A;  3CQZ C;  5TMC A;  2NVT C;  3WOD A;  2E2J C;  3FKI C;  2RD2 A;  3S1M C;  1GTS A;  4XSZ A;  3S1R C;  2L5N A;  4Y52 C;  4JYZ A;  3S2D C;  3LYW A;  4GZY A;  1Y1W C;  2WAQ D;  1QRT A;  3I4N C;  3HOU C;  2AE0 X;  2PPB A;  3KW2 A;  4G7Z A;  1SMY A;  1NYL A;  1R9T C;  3S1Q C;  3RZD C;  5HL7 S;  2ZJQ S;  4KMU A;  4IOC S;  1EUY A;  1FEU A;  2HZ7 A;  5D4D A;  4XLN A;  4A3F C;  1SFO C;  4A3C C;  2A6H A;  2VUM C;  1WCM C;  1I6H C;  4H4K A;  3GTM C;  2KPU A;  3H3V D;  4WFA S;  4Y7N C;  3HKZ D;  3HOV C;  1I3Q C;  4Q5S A;  5C44 C;  1O0C A;  4XSX A;  4IO9 S;  1Y1V C;  4A3K C;  2BE5 A;  2NVY C;  3S15 C;  1TWF C;  4BY7 C;  2PJJ A;  4ZH4 A;  3GTP C;  1YNJ A;  3GTJ C;  5HQH A;  2PMZ D;  1TWC C;  2PNW A;  4G7H A;  4A3L C;  4MQ9 A;  4OIP A;  4U67 S;  4KN7 A;  2RE8 A;  2R92 C;  4A3I C;  3HOY C;  1IW7 A;  3W2V B;  3I4M C;  4A3B C;  3HOX C;  4A93 C;  4AYB D;  4LLG A;  4LK0 A;  4OIN A;  1TWA C;  1V6Z A;  1BDF A;  3S16 C;  1QRS A;  2ZJP S;  5IYD C;  2JA7 C;  4JK1 A;  4A3M C;  4C3J C;  2PA8 D;  5FLM C;  3S2H C;  3GTK C;  2JA8 C;  1GTR A;  2NWA A;  1I6V A;  4A3J C;  4C3H C;  3S17 C;  1ZJW A;  2PI8 A;  1D6K A;  1TWH C;  3HOW C;  4X6A C;  4MEX A;  4KN4 A;  1EUQ A;  2R7Z C;  4WCE S;  3J7Z V;  1HQM A;  4UY8 8;  5JVH S;  4C3I C;  3RZO C;  4YFX A;  5C4X C;  3X1L B;  4OIQ A;  4YG2 A;  3GTG C;  4V19 4;  2E2H C;  5IZN A;  4BBR C;  1K83 C;  3W2W B;  4JXX A;  2Z0Y A;  4LK1 A;  4A3E C;  3S1N C;  4A3D C;  1YNN A;  3HOZ C;  3CF5 S;  2E2I C;  2B63 C;  2A69 A;  5GAH W;  2L3U A;  2CX8 A;  3H0G C;  2O5J A;  1DFU P;  4NOI A;  5GAD W;  2KQ1 A;  2R93 C;  2EGV A;  1ZYR A;  3M3Y C;  1TWG C;  3DLL S;  5BNZ A;  2NVQ C;  4YFK A;  2EGW A;  4IOA S;  4OIO A;  3GTO C;  3DXJ A;  2PIC A;  1NXZ A;  4OIR A;  5C4J C;  4P2B A;  3GTL C;  3PO3 C;  4G7O A;  1VHK A;  1EXD A;  2NVX C;  1Z85 A;  4MEY A;  4L69 A;  4QJV A;  5C3E C;  4WF9 S;  4BY1 C;  2JA6 C;  5JVG S;  3S14 C;  3GTQ C;  1UDX A;  5GAE W;  2G5D A;  3PIP S;  5IP7 C;  5DM6 S;  4BBS C;  4A3G C;  1O0B A;  2CW0 A;  3K7A C;  3PIO S;  1QTQ A;  1B75 A;  2YU9 C;  3PO2 C;  2ZJR S;  2A6E A;  2KXY A;  4QIW D;  4JXZ A;  1QRU A;  2Y0S D;  3CZB A;  3EQL A;  4YFN A;  2O5I A;  1I50 C;  5DM7 S;  4WFN S;  3AII A; 
#chains in the Genus database with same CATH homology
 4H4K A;  4WFA S;  1QRS A;  2ZJP S;  5GAG W;  3DLL S;  5BNZ A;  1O0C A;  4WFB S;  4IO9 S;  4IOA S;  1GTR A;  4H3S A;  4P2B A;  1EXD A;  1ZJW A;  1D6K A;  2RD2 A;  1DFU P;  1GTS A;  4WF9 S;  5JVG S;  1UDX A;  5GAE W;  1EUQ A;  3PIP S;  4WCE S;  3J7Z V;  5DM6 S;  4JYZ A;  5JVH S;  1O0B A;  4UY8 8;  3X1L B;  3PIO S;  1QTQ A;  4U67 S;  4V19 4;  1QRT A;  2RE8 A;  1B75 A;  2ZJR S;  5IZN A;  3W2V B;  4JXZ A;  1NYL A;  3W2W B;  4JXX A;  1QRU A;  5HL7 S;  2ZJQ S;  3CF5 S;  4IOC S;  1EUY A;  5GAH W;  2HZ7 A;  1FEU A;  5DM7 S;  4WFN S;  3AII A;  5GAD W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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