4WF9S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with telithromycin
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 24
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wf9S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wf9S02
3DLLS 2ZJQS 1DFUP 5DM6S 1QRUA 5GAEW 5GAGW 2RE8A 4UY88 1FEUA 4P2BA 1EUYA 1GTRA 4WCES 4WFAS 4IO9S 1QTQA 4IOAS 4WF9S 3J7ZV 1QRTA 1EUQA 5HL7S 2HZ7A 3CF5S 4WFBS 5JVGS 2RD2A 1ZJWA 1D6KA 5DM7S 5IZNA 4U67S 1GTSA 4H3SA 5BNZA 1O0BA 5JVHS 1QRSA 3PIOS 1NYLA 4WFNS 2ZJPS 4JYZA 5GADW 4JXXA 3PIPS 1EXDA 4JXZA 5GAHW 4IOCS 2ZJRS 1O0CA 1B75A 3AIIA
chains in the Genus database with same CATH superfamily
3W2WB 4BY1C 4ZH4A 4LLGA 2BE5A 4BY7C 2G5DA 1QRUA 2G6GA 3LYWA 5GAGW 5C3EC 1YNJA 1GTRA 4WCES 4IOAS 4WF9S 3HOXC 4A3FC 3GTOC 3HOVC 3S17C 3S1NC 3S2HC 3S1RC 4XLNA 5HL7S 1I3QC 2HZ7A 4BBSC 4A3CC 1WCMC 4OIRA 4WFBS 2L3UA 4G7ZA 5D4DA 3HOZC 3K7AC 3HOWC 2PNWA 2JA5C 2E2HC 3GTQC 5IP7C 3CQZC 4LJZA 4Y7NC 2ZJPS 2O5JA 4J3CA 5IYDC 4JYZA 5GADW 4NOIA 2EGVA 1EXDA 4JXZA 2NVYC 3EQLA 2ZJRS 5TMFA 4Q4ZA 2YU9C 1I6VA 3I4NC 4XSXA 2PPBA 2R93C 1ZYRA 2ZJQS 4YG2A 3I4MC 4YFKA 5DM6S 2A6EA 2R7ZC 3GTKC 5GAEW 3FKIC 4OIOA 1EUYA 4A3MC 4IO9S 2KPUA 1TWGC 1QRTA 1EUQA 2EGWA 5TMCA 3GTGC 5IYBC 3H3VD 3X1LB 5JVGS 2JA6C 4BXXC 4OIPA 1Y1WC 1ZJWA 4G7OA 4A3KC 1D6KA 5DM7S 3S1QC 2GAEA 1TWFC 1O0BA 2PMZD 4OIQA 5JVHS 3M3YC 2PICA 3CZBA 3HKZD 3PO3C 2PJJA 3HOYC 1Y1VC 4GZYA 3PIPS 3H0GC 2A6HA 1I6HC 1O0CA 1B75A 4E8BA 1R9TC 3DLLS 2Z0YA 4V194 1DFUP 4C3IC 4YFXA 2NVXC 4XSZA 3S2DC 3RZOC 4A3LC 3GTMC 4MEYA 2CX8A 2E2JC 1VHYA 4QIWD 3M4OC 4BBRC 3WODA 3GTLC 2NVQC 1TWHC 4AYBD 5IYCC 1UDXA 4L69A 2JA8C 4C3JC 2B63C 2RD2A 1TWCC 4QJVA 2KXYA 2E2IC 4U67S 1YNNA 1GTSA 4JK1A 2WAQD 5FLMC 4H3SA 2L5NA 3S16C 4KN4A 1IW7A 1K83C 3S15C 4Q5SA 3PIOS 4Y52C 4MEXA 1VHKA 3DXJA 4WFNS 2A69A 4C2MC 5C4XC 2NVTC 4LK1A 4JXXA 1I50C 1HQMA 1Z85A 5GAHW 2KQ1A 4A3GC 4MQ9A 3RZDC 4C3HC 4A3JC 2PA8D 2O5IA 2NWAA 2PI8A 4KMUA 2Y0SD 1SFOC 4XLPA 2RE8A 1SMYA 4UY88 1FEUA 5HQHA 5IP9C 4P2BA 3S14C 1QTQA 4WFAS 2CW0A 3J7ZV 4LK0A 3HOUC 3GTJC 3CF5S 2A68A 5C4JC 4G7HA 4A93C 1BDFA 4A3EC 3GTPC 2WB1D 1V6ZA 5IZNA 4KN7A 2R92C 4H4KA 3W2VB 5BNZA 2VUMC 4A3DC 4X6AC 1QRSA 1TWAC 5C44C 4YFNA 1NYLA 4OINA 1NXZA 2AE0X 4A3BC 2JA7C 4IOCS 4A3IC 3AIIA 3KW2A 3PO2C 3S1MC
chains in the Genus database with same CATH topology
3DLLS 3W2WB 4V194 2ZJQS 1DFUP 5DM6S 1QRUA 5GAEW 5GAGW 2RE8A 4UY88 1FEUA 4P2BA 1EUYA 1GTRA 4WCES 4WFAS 4IO9S 1QTQA 4IOAS 4WF9S 3J7ZV 1QRTA 1EUQA 5HL7S 2HZ7A 3CF5S 1UDXA 4WFBS 3X1LB 5JVGS 2RD2A 1ZJWA 1D6KA 5DM7S 5IZNA 4U67S 1GTSA 4H3SA 4H4KA 3W2VB 5BNZA 1O0BA 5JVHS 1QRSA 3PIOS 1NYLA 4WFNS 2ZJPS 4JYZA 5GADW 4JXXA 3PIPS 1EXDA 4JXZA 5GAHW 4IOCS 2ZJRS 1O0CA 1B75A 3AIIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DLL S;  2ZJQ S;  1DFU P;  5DM6 S;  1QRU A;  5GAE W;  5GAG W;  2RE8 A;  4UY8 8;  1FEU A;  4P2B A;  1EUY A;  1GTR A;  4WCE S;  4WFA S;  4IO9 S;  1QTQ A;  4IOA S;  4WF9 S;  3J7Z V;  1QRT A;  1EUQ A;  5HL7 S;  2HZ7 A;  3CF5 S;  4WFB S;  5JVG S;  2RD2 A;  1ZJW A;  1D6K A;  5DM7 S;  5IZN A;  4U67 S;  1GTS A;  4H3S A;  5BNZ A;  1O0B A;  5JVH S;  1QRS A;  3PIO S;  1NYL A;  4WFN S;  2ZJP S;  4JYZ A;  5GAD W;  4JXX A;  3PIP S;  1EXD A;  4JXZ A;  5GAH W;  4IOC S;  2ZJR S;  1O0C A;  1B75 A;  3AII A; 
#chains in the Genus database with same CATH topology
 3W2W B;  4BY1 C;  4ZH4 A;  4LLG A;  2BE5 A;  4BY7 C;  2G5D A;  1QRU A;  2G6G A;  3LYW A;  5GAG W;  5C3E C;  1YNJ A;  1GTR A;  4WCE S;  4IOA S;  4WF9 S;  3HOX C;  4A3F C;  3GTO C;  3HOV C;  3S17 C;  3S1N C;  3S2H C;  3S1R C;  4XLN A;  5HL7 S;  1I3Q C;  2HZ7 A;  4BBS C;  4A3C C;  1WCM C;  4OIR A;  4WFB S;  2L3U A;  4G7Z A;  5D4D A;  3HOZ C;  3K7A C;  3HOW C;  2PNW A;  2JA5 C;  2E2H C;  3GTQ C;  5IP7 C;  3CQZ C;  4LJZ A;  4Y7N C;  2ZJP S;  2O5J A;  4J3C A;  5IYD C;  4JYZ A;  5GAD W;  4NOI A;  2EGV A;  1EXD A;  4JXZ A;  2NVY C;  3EQL A;  2ZJR S;  5TMF A;  4Q4Z A;  2YU9 C;  1I6V A;  3I4N C;  4XSX A;  2PPB A;  2R93 C;  1ZYR A;  2ZJQ S;  4YG2 A;  3I4M C;  4YFK A;  5DM6 S;  2A6E A;  2R7Z C;  3GTK C;  5GAE W;  3FKI C;  4OIO A;  1EUY A;  4A3M C;  4IO9 S;  2KPU A;  1TWG C;  1QRT A;  1EUQ A;  2EGW A;  5TMC A;  3GTG C;  5IYB C;  3H3V D;  3X1L B;  5JVG S;  2JA6 C;  4BXX C;  4OIP A;  1Y1W C;  1ZJW A;  4G7O A;  4A3K C;  1D6K A;  5DM7 S;  3S1Q C;  2GAE A;  1TWF C;  1O0B A;  2PMZ D;  4OIQ A;  5JVH S;  3M3Y C;  2PIC A;  3CZB A;  3HKZ D;  3PO3 C;  2PJJ A;  3HOY C;  1Y1V C;  4GZY A;  3PIP S;  3H0G C;  2A6H A;  1I6H C;  1O0C A;  1B75 A;  4E8B A;  1R9T C;  3DLL S;  2Z0Y A;  4V19 4;  1DFU P;  4C3I C;  4YFX A;  2NVX C;  4XSZ A;  3S2D C;  3RZO C;  4A3L C;  3GTM C;  4MEY A;  2CX8 A;  2E2J C;  1VHY A;  4QIW D;  3M4O C;  4BBR C;  3WOD A;  3GTL C;  2NVQ C;  1TWH C;  4AYB D;  5IYC C;  1UDX A;  4L69 A;  2JA8 C;  4C3J C;  2B63 C;  2RD2 A;  1TWC C;  4QJV A;  2KXY A;  2E2I C;  4U67 S;  1YNN A;  1GTS A;  4JK1 A;  2WAQ D;  5FLM C;  4H3S A;  2L5N A;  3S16 C;  4KN4 A;  1IW7 A;  1K83 C;  3S15 C;  4Q5S A;  3PIO S;  4Y52 C;  4MEX A;  1VHK A;  3DXJ A;  4WFN S;  2A69 A;  4C2M C;  5C4X C;  2NVT C;  4LK1 A;  4JXX A;  1I50 C;  1HQM A;  1Z85 A;  5GAH W;  2KQ1 A;  4A3G C;  4MQ9 A;  3RZD C;  4C3H C;  4A3J C;  2PA8 D;  2O5I A;  2NWA A;  2PI8 A;  4KMU A;  2Y0S D;  1SFO C;  4XLP A;  2RE8 A;  1SMY A;  4UY8 8;  1FEU A;  5HQH A;  5IP9 C;  4P2B A;  3S14 C;  1QTQ A;  4WFA S;  2CW0 A;  3J7Z V;  4LK0 A;  3HOU C;  3GTJ C;  3CF5 S;  2A68 A;  5C4J C;  4G7H A;  4A93 C;  1BDF A;  4A3E C;  3GTP C;  2WB1 D;  1V6Z A;  5IZN A;  4KN7 A;  2R92 C;  4H4K A;  3W2V B;  5BNZ A;  2VUM C;  4A3D C;  4X6A C;  1QRS A;  1TWA C;  5C44 C;  4YFN A;  1NYL A;  4OIN A;  1NXZ A;  2AE0 X;  4A3B C;  2JA7 C;  4IOC S;  4A3I C;  3AII A;  3KW2 A;  3PO2 C;  3S1M C; 
#chains in the Genus database with same CATH homology
 3DLL S;  3W2W B;  4V19 4;  2ZJQ S;  1DFU P;  5DM6 S;  1QRU A;  5GAE W;  5GAG W;  2RE8 A;  4UY8 8;  1FEU A;  4P2B A;  1EUY A;  1GTR A;  4WCE S;  4WFA S;  4IO9 S;  1QTQ A;  4IOA S;  4WF9 S;  3J7Z V;  1QRT A;  1EUQ A;  5HL7 S;  2HZ7 A;  3CF5 S;  1UDX A;  4WFB S;  3X1L B;  5JVG S;  2RD2 A;  1ZJW A;  1D6K A;  5DM7 S;  5IZN A;  4U67 S;  1GTS A;  4H3S A;  4H4K A;  3W2V B;  5BNZ A;  1O0B A;  5JVH S;  1QRS A;  3PIO S;  1NYL A;  4WFN S;  2ZJP S;  4JYZ A;  5GAD W;  4JXX A;  3PIP S;  1EXD A;  4JXZ A;  5GAH W;  4IOC S;  2ZJR S;  1O0C A;  1B75 A;  3AII A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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