4WFAS

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with linezolid
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into species-specific features of the ribosome from the pathogen Staphylococcus aureus.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S rRNA
total genus 18
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2014-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfaS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfaS02
4WFNS 1D6KA 1DFUP 4WFBS 5BNZA 5GAEW 1O0BA 5GADW 3AIIA 1GTSA 5GAGW 5JVHS 5IZNA 1QRSA 1FEUA 3DLLS 5HL7S 1EUYA 2ZJPS 3J7ZV 2ZJRS 1QRTA 1EXDA 1EUQA 1NYLA 3PIOS 5JVGS 4H3SA 5DM6S 4IO9S 1O0CA 1GTRA 3PIPS 4P2BA 5DM7S 1QTQA 4JXZA 4WFAS 4U67S 2RD2A 4JYZA 2HZ7A 2RE8A 5GAHW 1ZJWA 4IOCS 2ZJQS 1QRUA 4JXXA 1B75A 4WCES 3CF5S 4IOAS 4UY88 4WF9S
chains in the Genus database with same CATH superfamily
3X1LB 3PO3C 1HQMA 1TWCC 1D6KA 4LJZA 5IYCC 2L5NA 5C4JC 2PPBA 2A6HA 3HOVC 5BNZA 1Y1VC 2NVTC 1R9TC 4A3MC 4XSXA 3WODA 1TWAC 4BY1C 5GADW 4KMUA 3AIIA 2O5IA 3GTPC 2PNWA 2KXYA 4L69A 1Y1WC 4LK0A 3H3VD 2YU9C 1QRSA 2Y0SD 3W2WB 4Y7NC 3S1QC 1EUYA 1I6HC 3J7ZV 3CQZC 1QRTA 4BY7C 5TMCA 3GTJC 1NYLA 2PA8D 1I3QC 4Q5SA 2EGVA 1QTQA 2E2HC 5IP9C 4WFAS 2RD2A 2WB1D 5IYDC 2HZ7A 1SMYA 4IOCS 1I6VA 3KW2A 4A3CC 4G7HA 4OIOA 3CF5S 4JXZA 2KQ1A 4A3BC 2JA5C 1SFOC 2R92C 2Z0YA 2B63C 5GAEW 4G7ZA 4OIQA 1O0BA 1VHKA 5C44C 2AE0X 1BDFA 1NXZA 3M4OC 4GZYA 2VUMC 4OINA 2CX8A 3S15C 3S1NC 4G7OA 4LK1A 1V6ZA 4A3LC 4E8BA 4C3HC 3LYWA 5C3EC 3PIOS 5JVGS 4IO9S 1TWHC 1GTRA 4P2BA 4MQ9A 4XSZA 4U67S 4YFXA 2R7ZC 4MEXA 2RE8A 5GAHW 4XLNA 3RZDC 3I4MC 3S1MC 2PJJA 3EQLA 2ZJQS 2GAEA 3I4NC 3S17C 4UY88 3HOXC 4WF9S 3K7AC 2NVXC 4WFNS 2BE5A 5TMFA 2NVQC 3HOZC 4WFBS 3S14C 4XLPA 4YG2A 4X6AC 5FLMC 4ZH4A 4J3CA 2NVYC 4BXXC 4BBSC 1Z85A 1GTSA 4YFNA 3HOUC 5GAGW 4MEYA 4NOIA 1ZYRA 4A3EC 2PI8A 5IZNA 1IW7A 1K83C 4OIPA 3DLLS 4C2MC 3GTMC 2L3UA 2O5JA 2KPUA 1I50C 1EXDA 4QIWD 1EUQA 4KN7A 4Q4ZA 4Y52C 3HOWC 1WCMC 4A3KC 3PIPS 2JA8C 5DM7S 3S16C 1ZJWA 4JK1A 4OIRA 1VHYA 4A3FC 4WCES 2PMZD 2PICA 2G6GA 4BBRC 3CZBA 2NWAA 3HKZD 1DFUP 4YFKA 3FKIC 3RZOC 3GTGC 3H0GC 2JA6C 2CW0A 4A93C 3PO2C 2WAQD 4A3DC 2G5DA 4H4KA 3GTQC 5JVHS 5HQHA 4A3IC 1FEUA 5D4DA 5HL7S 1TWFC 2JA7C 2EGWA 2ZJPS 2ZJRS 2E2JC 4AYBD 3S2HC 3GTLC 1UDXA 3DXJA 4LLGA 4QJVA 4H3SA 5DM6S 1O0CA 2A69A 3S2DC 4A3GC 2R93C 1YNJA 4KN4A 3W2VB 5IP7C 2E2IC 3GTOC 4C3JC 3GTKC 1TWGC 3HOYC 3S1RC 2A68A 2A6EA 3M3YC 1B75A 1QRUA 4JXXA 1YNNA 4C3IC 4A3JC 4V194 5C4XC 4JYZA 4IOAS 5IYBC
chains in the Genus database with same CATH topology
3X1LB 4WFNS 1D6KA 1DFUP 4WFBS 5BNZA 5GAEW 1O0BA 5GADW 3AIIA 1GTSA 4H4KA 5GAGW 5JVHS 5IZNA 1QRSA 1FEUA 3DLLS 3W2WB 5HL7S 1EUYA 2ZJPS 3J7ZV 2ZJRS 1QRTA 1EXDA 1EUQA 1NYLA 1UDXA 3PIOS 5JVGS 4H3SA 5DM6S 4IO9S 1O0CA 1GTRA 3PIPS 4P2BA 5DM7S 4V194 1QTQA 4WFAS 4U67S 2RD2A 4JYZA 3W2VB 2HZ7A 2RE8A 5GAHW 1ZJWA 4JXZA 4IOCS 2ZJQS 1QRUA 4JXXA 1B75A 4WCES 3CF5S 4IOAS 4UY88 4WF9S
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WFN S;  1D6K A;  1DFU P;  4WFB S;  5BNZ A;  5GAE W;  1O0B A;  5GAD W;  3AII A;  1GTS A;  5GAG W;  5JVH S;  5IZN A;  1QRS A;  1FEU A;  3DLL S;  5HL7 S;  1EUY A;  2ZJP S;  3J7Z V;  2ZJR S;  1QRT A;  1EXD A;  1EUQ A;  1NYL A;  3PIO S;  5JVG S;  4H3S A;  5DM6 S;  4IO9 S;  1O0C A;  1GTR A;  3PIP S;  4P2B A;  5DM7 S;  1QTQ A;  4JXZ A;  4WFA S;  4U67 S;  2RD2 A;  4JYZ A;  2HZ7 A;  2RE8 A;  5GAH W;  1ZJW A;  4IOC S;  2ZJQ S;  1QRU A;  4JXX A;  1B75 A;  4WCE S;  3CF5 S;  4IOA S;  4UY8 8;  4WF9 S; 
#chains in the Genus database with same CATH topology
 3X1L B;  3PO3 C;  1HQM A;  1TWC C;  1D6K A;  4LJZ A;  5IYC C;  2L5N A;  5C4J C;  2PPB A;  2A6H A;  3HOV C;  5BNZ A;  1Y1V C;  2NVT C;  1R9T C;  4A3M C;  4XSX A;  3WOD A;  1TWA C;  4BY1 C;  5GAD W;  4KMU A;  3AII A;  2O5I A;  3GTP C;  2PNW A;  2KXY A;  4L69 A;  1Y1W C;  4LK0 A;  3H3V D;  2YU9 C;  1QRS A;  2Y0S D;  3W2W B;  4Y7N C;  3S1Q C;  1EUY A;  1I6H C;  3J7Z V;  3CQZ C;  1QRT A;  4BY7 C;  5TMC A;  3GTJ C;  1NYL A;  2PA8 D;  1I3Q C;  4Q5S A;  2EGV A;  1QTQ A;  2E2H C;  5IP9 C;  4WFA S;  2RD2 A;  2WB1 D;  5IYD C;  2HZ7 A;  1SMY A;  4IOC S;  1I6V A;  3KW2 A;  4A3C C;  4G7H A;  4OIO A;  3CF5 S;  4JXZ A;  2KQ1 A;  4A3B C;  2JA5 C;  1SFO C;  2R92 C;  2Z0Y A;  2B63 C;  5GAE W;  4G7Z A;  4OIQ A;  1O0B A;  1VHK A;  5C44 C;  2AE0 X;  1BDF A;  1NXZ A;  3M4O C;  4GZY A;  2VUM C;  4OIN A;  2CX8 A;  3S15 C;  3S1N C;  4G7O A;  4LK1 A;  1V6Z A;  4A3L C;  4E8B A;  4C3H C;  3LYW A;  5C3E C;  3PIO S;  5JVG S;  4IO9 S;  1TWH C;  1GTR A;  4P2B A;  4MQ9 A;  4XSZ A;  4U67 S;  4YFX A;  2R7Z C;  4MEX A;  2RE8 A;  5GAH W;  4XLN A;  3RZD C;  3I4M C;  3S1M C;  2PJJ A;  3EQL A;  2ZJQ S;  2GAE A;  3I4N C;  3S17 C;  4UY8 8;  3HOX C;  4WF9 S;  3K7A C;  2NVX C;  4WFN S;  2BE5 A;  5TMF A;  2NVQ C;  3HOZ C;  4WFB S;  3S14 C;  4XLP A;  4YG2 A;  4X6A C;  5FLM C;  4ZH4 A;  4J3C A;  2NVY C;  4BXX C;  4BBS C;  1Z85 A;  1GTS A;  4YFN A;  3HOU C;  5GAG W;  4MEY A;  4NOI A;  1ZYR A;  4A3E C;  2PI8 A;  5IZN A;  1IW7 A;  1K83 C;  4OIP A;  3DLL S;  4C2M C;  3GTM C;  2L3U A;  2O5J A;  2KPU A;  1I50 C;  1EXD A;  4QIW D;  1EUQ A;  4KN7 A;  4Q4Z A;  4Y52 C;  3HOW C;  1WCM C;  4A3K C;  3PIP S;  2JA8 C;  5DM7 S;  3S16 C;  1ZJW A;  4JK1 A;  4OIR A;  1VHY A;  4A3F C;  4WCE S;  2PMZ D;  2PIC A;  2G6G A;  4BBR C;  3CZB A;  2NWA A;  3HKZ D;  1DFU P;  4YFK A;  3FKI C;  3RZO C;  3GTG C;  3H0G C;  2JA6 C;  2CW0 A;  4A93 C;  3PO2 C;  2WAQ D;  4A3D C;  2G5D A;  4H4K A;  3GTQ C;  5JVH S;  5HQH A;  4A3I C;  1FEU A;  5D4D A;  5HL7 S;  1TWF C;  2JA7 C;  2EGW A;  2ZJP S;  2ZJR S;  2E2J C;  4AYB D;  3S2H C;  3GTL C;  1UDX A;  3DXJ A;  4LLG A;  4QJV A;  4H3S A;  5DM6 S;  1O0C A;  2A69 A;  3S2D C;  4A3G C;  2R93 C;  1YNJ A;  4KN4 A;  3W2V B;  5IP7 C;  2E2I C;  3GTO C;  4C3J C;  3GTK C;  1TWG C;  3HOY C;  3S1R C;  2A68 A;  2A6E A;  3M3Y C;  1B75 A;  1QRU A;  4JXX A;  1YNN A;  4C3I C;  4A3J C;  4V19 4;  5C4X C;  4JYZ A;  4IOA S;  5IYB C; 
#chains in the Genus database with same CATH homology
 3X1L B;  4WFN S;  1D6K A;  1DFU P;  4WFB S;  5BNZ A;  5GAE W;  1O0B A;  5GAD W;  3AII A;  1GTS A;  4H4K A;  5GAG W;  5JVH S;  5IZN A;  1QRS A;  1FEU A;  3DLL S;  3W2W B;  5HL7 S;  1EUY A;  2ZJP S;  3J7Z V;  2ZJR S;  1QRT A;  1EXD A;  1EUQ A;  1NYL A;  1UDX A;  3PIO S;  5JVG S;  4H3S A;  5DM6 S;  4IO9 S;  1O0C A;  1GTR A;  3PIP S;  4P2B A;  5DM7 S;  4V19 4;  1QTQ A;  4WFA S;  4U67 S;  2RD2 A;  4JYZ A;  3W2V B;  2HZ7 A;  2RE8 A;  5GAH W;  1ZJW A;  4JXZ A;  4IOC S;  2ZJQ S;  1QRU A;  4JXX A;  1B75 A;  4WCE S;  3CF5 S;  4IOA S;  4UY8 8;  4WF9 S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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