4WFNS

Crystal structure of the large ribosomal subunit (50s) of deinococcus radiodurans containing a three residue insertion in l22 in complex with erythromycin
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 19
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2014-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfnS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfnS02
2ZJPS 1GTSA 5BNZA 2ZJQS 1QRSA 1GTRA 5GAHW 2RE8A 4H3SA 4WFBS 4WF9S 5DM7S 4WFAS 4U67S 3J7ZV 2HZ7A 5IZNA 4WFNS 4JYZA 1EUQA 5JVGS 1O0BA 4UY88 3DLLS 1QRUA 1NYLA 1FEUA 1D6KA 4IOCS 1QTQA 1EUYA 3CF5S 5DM6S 1O0CA 1DFUP 4P2BA 1QRTA 5GADW 4JXZA 4IOAS 5GAGW 4WCES 4IO9S 1B75A 2RD2A 5JVHS 3AIIA 1ZJWA 3PIOS 5HL7S 3PIPS 2ZJRS 4JXXA 5GAEW 1EXDA
chains in the Genus database with same CATH superfamily
2PJJA 4A3CC 4A3FC 5IYDC 4H3SA 4WF9S 4OIPA 4YG2A 5DM7S 2L3UA 3GTJC 4WFAS 1Y1WC 3S14C 4OIOA 4J3CA 4JK1A 4C3HC 4Q4ZA 2Z0YA 3J7ZV 4BXXC 2B63C 2L5NA 4JYZA 2PA8D 5JVGS 2A69A 4QJVA 3W2WB 3DLLS 1TWGC 1FEUA 2BE5A 5FLMC 4G7HA 4A3EC 1D6KA 4IOCS 4BY1C 3CF5S 5IP9C 5TMCA 4NOIA 4H4KA 3HOXC 4KN7A 4MEYA 4YFKA 1I6VA 4IO9S 3W2VB 3GTOC 4LK0A 2O5JA 5JVHS 3AIIA 4QIWD 4OIQA 3PO2C 1TWFC 4JXXA 3FKIC 3HOYC 1EXDA 3KW2A 3M3YC 4ZH4A 4GZYA 2ZJPS 1UDXA 1GTSA 1I50C 4V194 2CX8A 4BBRC 2RE8A 2JA8C 4X6AC 1Y1VC 4A3DC 4KN4A 2E2JC 2WB1D 2VUMC 4LLGA 4A3GC 2JA6C 1I6HC 1WCMC 4KMUA 1NXZA 4XSXA 4E8BA 4LJZA 1NYLA 3M4OC 2A68A 4YFNA 1EUYA 2KQ1A 3S1MC 1BDFA 4XLNA 2E2IC 1HQMA 3RZDC 4JXZA 4OINA 2EGVA 5C4JC 3H3VD 2PPBA 1Z85A 4XSZA 4C2MC 3GTPC 5C4XC 2Y0SD 5IP7C 2KXYA 3GTQC 5HL7S 4BBSC 1YNNA 3HKZD 2JA5C 2PMZD 1R9TC 5TMFA 3K7AC 2KPUA 1GTRA 5GAHW 3WODA 4Y7NC 4WFBS 4AYBD 4YFXA 5IYCC 1TWCC 4LK1A 2HZ7A 1K83C 4WFNS 2E2HC 3HOWC 2PI8A 2GAEA 2O5IA 3S2HC 5HQHA 1QTQA 3CZBA 1TWAC 4OIRA 3GTLC 2NWAA 1O0CA 5IYBC 3S1QC 2CW0A 1VHKA 4P2BA 3S1RC 4G7OA 5C44C 1QRTA 2PNWA 3GTMC 3PO3C 3HOZC 2AE0X 5GAGW 4WCES 2YU9C 3HOUC 3I4MC 1V6ZA 1B75A 2NVYC 3EQLA 1ZJWA 3S16C 3H0GC 4A3JC 3X1LB 2R92C 3S17C 1I3QC 2NVQC 4BY7C 4Q5SA 5D4DA 1SMYA 1TWHC 2WAQD 4A3MC 2G6GA 1IW7A 5BNZA 2ZJQS 1QRSA 3RZOC 1ZYRA 4XLPA 2R93C 4U67S 4A3LC 3LYWA 3S15C 1YNJA 5IZNA 1EUQA 1O0BA 4A3IC 4UY88 4A3BC 2JA7C 2R7ZC 1QRUA 5C3EC 1DFUP 5DM6S 2A6EA 3CQZC 2NVTC 4C3JC 5GADW 2PICA 4C3IC 4IOAS 4G7ZA 3DXJA 3GTKC 4Y52C 2RD2A 1VHYA 3HOVC 4A93C 4MEXA 2A6HA 3PIOS 4MQ9A 2EGWA 3PIPS 2ZJRS 4L69A 1SFOC 2NVXC 3S2DC 4A3KC 5GAEW 3GTGC 3I4NC 2G5DA 3S1NC
chains in the Genus database with same CATH topology
2ZJPS 1UDXA 5BNZA 2ZJQS 1GTSA 1QRSA 4V194 1GTRA 5GAHW 2RE8A 4H3SA 4WFBS 4WF9S 5DM7S 4WFAS 4U67S 3J7ZV 2HZ7A 5IZNA 4WFNS 4JYZA 1EUQA 5JVGS 1O0BA 4UY88 3W2WB 3DLLS 1QRUA 1NYLA 1FEUA 1D6KA 4IOCS 1QTQA 1EUYA 3CF5S 5DM6S 1O0CA 1DFUP 4P2BA 4H4KA 1QRTA 5GADW 4JXZA 4IOAS 5GAGW 4WCES 4IO9S 3W2VB 1B75A 2RD2A 5JVHS 3AIIA 1ZJWA 3PIOS 3X1LB 5HL7S 3PIPS 2ZJRS 4JXXA 5GAEW 1EXDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJP S;  1GTS A;  5BNZ A;  2ZJQ S;  1QRS A;  1GTR A;  5GAH W;  2RE8 A;  4H3S A;  4WFB S;  4WF9 S;  5DM7 S;  4WFA S;  4U67 S;  3J7Z V;  2HZ7 A;  5IZN A;  4WFN S;  4JYZ A;  1EUQ A;  5JVG S;  1O0B A;  4UY8 8;  3DLL S;  1QRU A;  1NYL A;  1FEU A;  1D6K A;  4IOC S;  1QTQ A;  1EUY A;  3CF5 S;  5DM6 S;  1O0C A;  1DFU P;  4P2B A;  1QRT A;  5GAD W;  4JXZ A;  4IOA S;  5GAG W;  4WCE S;  4IO9 S;  1B75 A;  2RD2 A;  5JVH S;  3AII A;  1ZJW A;  3PIO S;  5HL7 S;  3PIP S;  2ZJR S;  4JXX A;  5GAE W;  1EXD A; 
#chains in the Genus database with same CATH topology
 2PJJ A;  4A3C C;  4A3F C;  5IYD C;  4H3S A;  4WF9 S;  4OIP A;  4YG2 A;  5DM7 S;  2L3U A;  3GTJ C;  4WFA S;  1Y1W C;  3S14 C;  4OIO A;  4J3C A;  4JK1 A;  4C3H C;  4Q4Z A;  2Z0Y A;  3J7Z V;  4BXX C;  2B63 C;  2L5N A;  4JYZ A;  2PA8 D;  5JVG S;  2A69 A;  4QJV A;  3W2W B;  3DLL S;  1TWG C;  1FEU A;  2BE5 A;  5FLM C;  4G7H A;  4A3E C;  1D6K A;  4IOC S;  4BY1 C;  3CF5 S;  5IP9 C;  5TMC A;  4NOI A;  4H4K A;  3HOX C;  4KN7 A;  4MEY A;  4YFK A;  1I6V A;  4IO9 S;  3W2V B;  3GTO C;  4LK0 A;  2O5J A;  5JVH S;  3AII A;  4QIW D;  4OIQ A;  3PO2 C;  1TWF C;  4JXX A;  3FKI C;  3HOY C;  1EXD A;  3KW2 A;  3M3Y C;  4ZH4 A;  4GZY A;  2ZJP S;  1UDX A;  1GTS A;  1I50 C;  4V19 4;  2CX8 A;  4BBR C;  2RE8 A;  2JA8 C;  4X6A C;  1Y1V C;  4A3D C;  4KN4 A;  2E2J C;  2WB1 D;  2VUM C;  4LLG A;  4A3G C;  2JA6 C;  1I6H C;  1WCM C;  4KMU A;  1NXZ A;  4XSX A;  4E8B A;  4LJZ A;  1NYL A;  3M4O C;  2A68 A;  4YFN A;  1EUY A;  2KQ1 A;  3S1M C;  1BDF A;  4XLN A;  2E2I C;  1HQM A;  3RZD C;  4JXZ A;  4OIN A;  2EGV A;  5C4J C;  3H3V D;  2PPB A;  1Z85 A;  4XSZ A;  4C2M C;  3GTP C;  5C4X C;  2Y0S D;  5IP7 C;  2KXY A;  3GTQ C;  5HL7 S;  4BBS C;  1YNN A;  3HKZ D;  2JA5 C;  2PMZ D;  1R9T C;  5TMF A;  3K7A C;  2KPU A;  1GTR A;  5GAH W;  3WOD A;  4Y7N C;  4WFB S;  4AYB D;  4YFX A;  5IYC C;  1TWC C;  4LK1 A;  2HZ7 A;  1K83 C;  4WFN S;  2E2H C;  3HOW C;  2PI8 A;  2GAE A;  2O5I A;  3S2H C;  5HQH A;  1QTQ A;  3CZB A;  1TWA C;  4OIR A;  3GTL C;  2NWA A;  1O0C A;  5IYB C;  3S1Q C;  2CW0 A;  1VHK A;  4P2B A;  3S1R C;  4G7O A;  5C44 C;  1QRT A;  2PNW A;  3GTM C;  3PO3 C;  3HOZ C;  2AE0 X;  5GAG W;  4WCE S;  2YU9 C;  3HOU C;  3I4M C;  1V6Z A;  1B75 A;  2NVY C;  3EQL A;  1ZJW A;  3S16 C;  3H0G C;  4A3J C;  3X1L B;  2R92 C;  3S17 C;  1I3Q C;  2NVQ C;  4BY7 C;  4Q5S A;  5D4D A;  1SMY A;  1TWH C;  2WAQ D;  4A3M C;  2G6G A;  1IW7 A;  5BNZ A;  2ZJQ S;  1QRS A;  3RZO C;  1ZYR A;  4XLP A;  2R93 C;  4U67 S;  4A3L C;  3LYW A;  3S15 C;  1YNJ A;  5IZN A;  1EUQ A;  1O0B A;  4A3I C;  4UY8 8;  4A3B C;  2JA7 C;  2R7Z C;  1QRU A;  5C3E C;  1DFU P;  5DM6 S;  2A6E A;  3CQZ C;  2NVT C;  4C3J C;  5GAD W;  2PIC A;  4C3I C;  4IOA S;  4G7Z A;  3DXJ A;  3GTK C;  4Y52 C;  2RD2 A;  1VHY A;  3HOV C;  4A93 C;  4MEX A;  2A6H A;  3PIO S;  4MQ9 A;  2EGW A;  3PIP S;  2ZJR S;  4L69 A;  1SFO C;  2NVX C;  3S2D C;  4A3K C;  5GAE W;  3GTG C;  3I4N C;  2G5D A;  3S1N C; 
#chains in the Genus database with same CATH homology
 2ZJP S;  1UDX A;  5BNZ A;  2ZJQ S;  1GTS A;  1QRS A;  4V19 4;  1GTR A;  5GAH W;  2RE8 A;  4H3S A;  4WFB S;  4WF9 S;  5DM7 S;  4WFA S;  4U67 S;  3J7Z V;  2HZ7 A;  5IZN A;  4WFN S;  4JYZ A;  1EUQ A;  5JVG S;  1O0B A;  4UY8 8;  3W2W B;  3DLL S;  1QRU A;  1NYL A;  1FEU A;  1D6K A;  4IOC S;  1QTQ A;  1EUY A;  3CF5 S;  5DM6 S;  1O0C A;  1DFU P;  4P2B A;  4H4K A;  1QRT A;  5GAD W;  4JXZ A;  4IOA S;  5GAG W;  4WCE S;  4IO9 S;  3W2V B;  1B75 A;  2RD2 A;  5JVH S;  3AII A;  1ZJW A;  3PIO S;  3X1L B;  5HL7 S;  3PIP S;  2ZJR S;  4JXX A;  5GAE W;  1EXD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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