5DM7S

Crystal structure of the 50s ribosomal subunit from deinococcus radiodurans in complex with hygromycin a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L1
total genus 19
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2015-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5dm7S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5dm7S02
1QRTA 1EXDA 4H3SA 4JYZA 4U67S 4WFAS 1DFUP 5JVGS 3PIOS 2ZJPS 5GAHW 3PIPS 1ZJWA 3AIIA 5GADW 1GTSA 1FEUA 1QRSA 3J7ZV 5DM7S 1D6KA 5GAEW 2HZ7A 3DLLS 2ZJRS 3CF5S 2ZJQS 5IZNA 2RD2A 1O0CA 1NYLA 4JXZA 4WFBS 1B75A 4IO9S 1EUQA 1QTQA 5GAGW 4WCES 1EUYA 1QRUA 4WF9S 4IOAS 5BNZA 4JXXA 1GTRA 4UY88 5JVHS 4WFNS 4P2BA 5DM6S 5HL7S 2RE8A 1O0BA 4IOCS
chains in the Genus database with same CATH superfamily
2E2HC 4A3FC 3GTGC 1HQMA 2E2IC 3GTPC 1EXDA 2JA5C 4BY1C 1TWFC 2PPBA 3M4OC 2R93C 4X6AC 1YNJA 5C44C 4OIPA 1Y1VC 3FKIC 4A93C 4MEYA 2NWAA 5IYDC 2WAQD 4YFNA 3S2HC 2KQ1A 1D6KA 2HZ7A 5IP7C 4L69A 2AE0X 3GTOC 1NYLA 4JXZA 4WFBS 3W2WB 4YG2A 4J3CA 5GAGW 4NOIA 1QRUA 5JVHS 4XLPA 4LLGA 1WCMC 4BY7C 5IP9C 4Q5SA 2O5IA 2KXYA 5DM6S 3M3YC 3PO2C 4A3LC 1O0BA 2G6GA 4IOCS 3LYWA 3S14C 4BXXC 4KMUA 4H3SA 1V6ZA 5D4DA 4OIRA 3I4NC 4A3BC 2B63C 1SMYA 2EGVA 3GTJC 3HOYC 2O5JA 3GTQC 5FLMC 3PIPS 1IW7A 1TWAC 3AIIA 1I6HC 1FEUA 1QRSA 3GTMC 2PA8D 4A3DC 5GAEW 5TMFA 2NVQC 3DLLS 2JA7C 4ZH4A 4QJVA 3CF5S 4C3JC 1Y1WC 5IZNA 4LK0A 3X1LB 2RD2A 4BBRC 4A3IC 1ZYRA 3H3VD 2A68A 3RZDC 2YU9C 5TMCA 4C2MC 4OINA 2PJJA 2PMZD 2EGWA 4IOAS 3S1NC 3HOXC 2Y0SD 4OIOA 1I50C 4Q4ZA 5IYCC 2NVTC 5C4JC 2KPUA 4Y52C 1SFOC 2PNWA 1QRTA 1BDFA 4C3HC 2NVXC 4A3CC 3WODA 2Z0YA 3S1RC 2PI8A 4JYZA 3HOUC 4U67S 3HOZC 4WFAS 1DFUP 4A3GC 4G7OA 2CW0A 2CX8A 3CZBA 2BE5A 4YFKA 1YNNA 2L3UA 1GTSA 2JA8C 3DXJA 4LK1A 1VHYA 4MQ9A 4G7HA 1TWHC 2A69A 2L5NA 2R7ZC 2ZJQS 4Y7NC 5C4XC 4YFXA 1O0CA 1B75A 1QTQA 4WCES 5C3EC 1R9TC 4XSZA 3EQLA 3HKZD 3HOVC 1UDXA 4LJZA 2R92C 4WF9S 3S17C 3K7AC 3KW2A 4JXXA 3PO3C 4UY88 2A6EA 4AYBD 4WFNS 3GTKC 2E2JC 2RE8A 3S16C 4XLNA 4GZYA 1TWCC 2A6HA 4KN7A 4H4KA 4XSXA 3CQZC 2NVYC 2GAEA 5JVGS 4BBSC 3PIOS 2ZJPS 3HOWC 5GAHW 3S2DC 4G7ZA 4E8BA 4MEXA 4A3JC 5GADW 3I4MC 3J7ZV 5DM7S 2WB1D 1Z85A 1K83C 3S1MC 2ZJRS 2JA6C 4KN4A 3S1QC 4IO9S 2G5DA 1EUQA 4V194 4JK1A 1VHKA 1EUYA 4A3EC 4A3MC 3W2VB 1TWGC 2PICA 4A3KC 4OIQA 1I3QC 3H0GC 4C3IC 2VUMC 5BNZA 1GTRA 1NXZA 4QIWD 5IYBC 3S15C 1I6VA 3RZOC 3GTLC 4P2BA 5HL7S 5HQHA 1ZJWA
chains in the Genus database with same CATH topology
1QRTA 4H4KA 1EXDA 4H3SA 4JYZA 4U67S 4WFAS 1DFUP 5JVGS 3PIOS 2ZJPS 5GAHW 3PIPS 1ZJWA 1B75A 3AIIA 5GADW 1GTSA 1FEUA 1QRSA 3J7ZV 5DM7S 1D6KA 5GAEW 2HZ7A 3DLLS 2ZJRS 3CF5S 2ZJQS 5IZNA 3X1LB 2RD2A 1O0CA 1NYLA 4JXZA 4WFBS 3W2WB 4IO9S 1EUQA 4V194 1QTQA 5GAGW 4WCES 1EUYA 3W2VB 1UDXA 1QRUA 4WF9S 4IOAS 5BNZA 4JXXA 1GTRA 4UY88 5JVHS 4WFNS 4P2BA 5DM6S 5HL7S 2RE8A 1O0BA 4IOCS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QRT A;  1EXD A;  4H3S A;  4JYZ A;  4U67 S;  4WFA S;  1DFU P;  5JVG S;  3PIO S;  2ZJP S;  5GAH W;  3PIP S;  1ZJW A;  3AII A;  5GAD W;  1GTS A;  1FEU A;  1QRS A;  3J7Z V;  5DM7 S;  1D6K A;  5GAE W;  2HZ7 A;  3DLL S;  2ZJR S;  3CF5 S;  2ZJQ S;  5IZN A;  2RD2 A;  1O0C A;  1NYL A;  4JXZ A;  4WFB S;  1B75 A;  4IO9 S;  1EUQ A;  1QTQ A;  5GAG W;  4WCE S;  1EUY A;  1QRU A;  4WF9 S;  4IOA S;  5BNZ A;  4JXX A;  1GTR A;  4UY8 8;  5JVH S;  4WFN S;  4P2B A;  5DM6 S;  5HL7 S;  2RE8 A;  1O0B A;  4IOC S; 
#chains in the Genus database with same CATH topology
 2E2H C;  4A3F C;  3GTG C;  1HQM A;  2E2I C;  3GTP C;  1EXD A;  2JA5 C;  4BY1 C;  1TWF C;  2PPB A;  3M4O C;  2R93 C;  4X6A C;  1YNJ A;  5C44 C;  4OIP A;  1Y1V C;  3FKI C;  4A93 C;  4MEY A;  2NWA A;  5IYD C;  2WAQ D;  4YFN A;  3S2H C;  2KQ1 A;  1D6K A;  2HZ7 A;  5IP7 C;  4L69 A;  2AE0 X;  3GTO C;  1NYL A;  4JXZ A;  4WFB S;  3W2W B;  4YG2 A;  4J3C A;  5GAG W;  4NOI A;  1QRU A;  5JVH S;  4XLP A;  4LLG A;  1WCM C;  4BY7 C;  5IP9 C;  4Q5S A;  2O5I A;  2KXY A;  5DM6 S;  3M3Y C;  3PO2 C;  4A3L C;  1O0B A;  2G6G A;  4IOC S;  3LYW A;  3S14 C;  4BXX C;  4KMU A;  4H3S A;  1V6Z A;  5D4D A;  4OIR A;  3I4N C;  4A3B C;  2B63 C;  1SMY A;  2EGV A;  3GTJ C;  3HOY C;  2O5J A;  3GTQ C;  5FLM C;  3PIP S;  1IW7 A;  1TWA C;  3AII A;  1I6H C;  1FEU A;  1QRS A;  3GTM C;  2PA8 D;  4A3D C;  5GAE W;  5TMF A;  2NVQ C;  3DLL S;  2JA7 C;  4ZH4 A;  4QJV A;  3CF5 S;  4C3J C;  1Y1W C;  5IZN A;  4LK0 A;  3X1L B;  2RD2 A;  4BBR C;  4A3I C;  1ZYR A;  3H3V D;  2A68 A;  3RZD C;  2YU9 C;  5TMC A;  4C2M C;  4OIN A;  2PJJ A;  2PMZ D;  2EGW A;  4IOA S;  3S1N C;  3HOX C;  2Y0S D;  4OIO A;  1I50 C;  4Q4Z A;  5IYC C;  2NVT C;  5C4J C;  2KPU A;  4Y52 C;  1SFO C;  2PNW A;  1QRT A;  1BDF A;  4C3H C;  2NVX C;  4A3C C;  3WOD A;  2Z0Y A;  3S1R C;  2PI8 A;  4JYZ A;  3HOU C;  4U67 S;  3HOZ C;  4WFA S;  1DFU P;  4A3G C;  4G7O A;  2CW0 A;  2CX8 A;  3CZB A;  2BE5 A;  4YFK A;  1YNN A;  2L3U A;  1GTS A;  2JA8 C;  3DXJ A;  4LK1 A;  1VHY A;  4MQ9 A;  4G7H A;  1TWH C;  2A69 A;  2L5N A;  2R7Z C;  2ZJQ S;  4Y7N C;  5C4X C;  4YFX A;  1O0C A;  1B75 A;  1QTQ A;  4WCE S;  5C3E C;  1R9T C;  4XSZ A;  3EQL A;  3HKZ D;  3HOV C;  1UDX A;  4LJZ A;  2R92 C;  4WF9 S;  3S17 C;  3K7A C;  3KW2 A;  4JXX A;  3PO3 C;  4UY8 8;  2A6E A;  4AYB D;  4WFN S;  3GTK C;  2E2J C;  2RE8 A;  3S16 C;  4XLN A;  4GZY A;  1TWC C;  2A6H A;  4KN7 A;  4H4K A;  4XSX A;  3CQZ C;  2NVY C;  2GAE A;  5JVG S;  4BBS C;  3PIO S;  2ZJP S;  3HOW C;  5GAH W;  3S2D C;  4G7Z A;  4E8B A;  4MEX A;  4A3J C;  5GAD W;  3I4M C;  3J7Z V;  5DM7 S;  2WB1 D;  1Z85 A;  1K83 C;  3S1M C;  2ZJR S;  2JA6 C;  4KN4 A;  3S1Q C;  4IO9 S;  2G5D A;  1EUQ A;  4V19 4;  4JK1 A;  1VHK A;  1EUY A;  4A3E C;  4A3M C;  3W2V B;  1TWG C;  2PIC A;  4A3K C;  4OIQ A;  1I3Q C;  3H0G C;  4C3I C;  2VUM C;  5BNZ A;  1GTR A;  1NXZ A;  4QIW D;  5IYB C;  3S15 C;  1I6V A;  3RZO C;  3GTL C;  4P2B A;  5HL7 S;  5HQH A;  1ZJW A; 
#chains in the Genus database with same CATH homology
 1QRT A;  4H4K A;  1EXD A;  4H3S A;  4JYZ A;  4U67 S;  4WFA S;  1DFU P;  5JVG S;  3PIO S;  2ZJP S;  5GAH W;  3PIP S;  1ZJW A;  1B75 A;  3AII A;  5GAD W;  1GTS A;  1FEU A;  1QRS A;  3J7Z V;  5DM7 S;  1D6K A;  5GAE W;  2HZ7 A;  3DLL S;  2ZJR S;  3CF5 S;  2ZJQ S;  5IZN A;  3X1L B;  2RD2 A;  1O0C A;  1NYL A;  4JXZ A;  4WFB S;  3W2W B;  4IO9 S;  1EUQ A;  4V19 4;  1QTQ A;  5GAG W;  4WCE S;  1EUY A;  3W2V B;  1UDX A;  1QRU A;  4WF9 S;  4IOA S;  5BNZ A;  4JXX A;  1GTR A;  4UY8 8;  5JVH S;  4WFN S;  4P2B A;  5DM6 S;  5HL7 S;  2RE8 A;  1O0B A;  4IOC S; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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