5HL7S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 22
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5hl7S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5hl7S02
4P2BA 4IOCS 1GTSA 2ZJPS 4JYZA 5IZNA 1O0CA 1QRTA 3DLLS 4IOAS 5HL7S 4UY88 3AIIA 2RD2A 5GAGW 1QRUA 4WFAS 4WFBS 4WFNS 1EUYA 3PIOS 1DFUP 1D6KA 1QTQA 1NYLA 1O0BA 4IO9S 5GADW 1QRSA 5DM6S 4WF9S 3J7ZV 3CF5S 1FEUA 4JXXA 2RE8A 5DM7S 5BNZA 4JXZA 4H3SA 5GAEW 3PIPS 2ZJRS 1EXDA 2ZJQS 4U67S 2HZ7A 5JVHS 1EUQA 5GAHW 1GTRA 5JVGS 4WCES 1ZJWA 1B75A
chains in the Genus database with same CATH superfamily
4P2BA 4BBSC 4IOCS 2EGVA 1GTSA 2G5DA 2KXYA 1QRTA 3HOXC 4Y7NC 4G7OA 2R92C 5HL7S 1SFOC 3AIIA 1HQMA 1VHKA 5FLMC 4QIWD 2NVXC 3S16C 3W2VB 1EUYA 2Z0YA 3I4NC 3S1RC 3CQZC 4A3IC 2GAEA 4A3MC 1YNJA 2EGWA 3GTKC 4NOIA 4Y52C 4XLPA 5IYDC 5HQHA 2NWAA 1TWFC 3RZDC 3S1MC 5BNZA 5GAEW 3PIPS 2ZJRS 2PPBA 1I3QC 1Y1VC 2L3UA 5TMFA 3DXJA 2KQ1A 2PMZD 1EUQA 4C3JC 4A3EC 4J3CA 1ZJWA 1WCMC 1TWAC 3HKZD 2YU9C 4BY1C 2JA7C 2ZJPS 4JYZA 5C44C 5IP7C 1O0CA 4IOAS 2VUMC 2PICA 2PI8A 4LLGA 4MQ9A 2NVQC 3HOWC 2A69A 2O5JA 5IYBC 2A6EA 4WFAS 2CW0A 2Y0SD 4YFNA 4WFNS 3GTJC 4BXXC 3K7AC 1Z85A 3PIOS 1DFUP 1IW7A 3FKIC 4KMUA 1VHYA 4ZH4A 4YFXA 4Q4ZA 4A3FC 1O0BA 4A3JC 4E8BA 5GADW 1BDFA 3LYWA 4C3HC 1V6ZA 5DM6S 1TWCC 4BBRC 4KN7A 4WF9S 4MEXA 3J7ZV 1FEUA 4LK1A 3GTPC 3GTGC 2A68A 2NVTC 3S1NC 4JK1A 5IYCC 2A6HA 1TWGC 2JA8C 4A3DC 1EXDA 2WB1D 2PNWA 3HOUC 3RZOC 3HOZC 3EQLA 4A93C 3GTQC 5C4XC 5GAHW 3PO2C 5TMCA 5C4JC 4OIPA 2E2HC 3GTOC 3S1QC 4OIQA 4GZYA 3S17C 1ZYRA 5IZNA 5IP9C 3DLLS 4LK0A 1UDXA 4UY88 2RD2A 1QRUA 2E2JC 5D4DA 2B63C 4A3BC 4BY7C 1YNNA 2PJJA 1D6KA 3H0GC 4XLNA 3CZBA 2G6GA 1NYLA 4IO9S 2JA5C 1QRSA 2KPUA 4G7ZA 1I6VA 1R9TC 4A3CC 3S2DC 5DM7S 3S14C 4YFKA 4H3SA 2L5NA 4YG2A 3WODA 4XSZA 4QJVA 4OIOA 2ZJQS 4LJZA 4A3KC 3M4OC 4H4KA 5JVHS 2NVYC 4A3GC 1GTRA 5JVGS 4WCES 4XSXA 1I6HC 4X6AC 4C3IC 2PA8D 2BE5A 3S15C 5GAGW 2AE0X 2CX8A 1NXZA 4WFBS 3I4MC 3S2HC 4AYBD 4C2MC 1K83C 4OIRA 1Y1WC 3W2WB 4L69A 1QTQA 1TWHC 3GTMC 4Q5SA 1I50C 2R93C 3KW2A 3CF5S 1SMYA 4JXXA 2RE8A 4G7HA 4OINA 4JXZA 3HOVC 2JA6C 5C3EC 2WAQD 4KN4A 4U67S 2E2IC 2HZ7A 4V194 3H3VD 3HOYC 3PO3C 3X1LB 4A3LC 2O5IA 2R7ZC 4MEYA 1B75A 3GTLC 3M3YC
chains in the Genus database with same CATH topology
4P2BA 4IOCS 1GTSA 2ZJPS 4JYZA 5IZNA 1O0CA 1QRTA 3DLLS 4IOAS 1UDXA 5HL7S 4UY88 3AIIA 2RD2A 5GAGW 1QRUA 4WFAS 4WFBS 3W2VB 4WFNS 1EUYA 3PIOS 1DFUP 1D6KA 3W2WB 1QTQA 1NYLA 1O0BA 4IO9S 5GADW 1QRSA 5DM6S 4WF9S 3J7ZV 3CF5S 1FEUA 4JXXA 2RE8A 5DM7S 5BNZA 4JXZA 4H3SA 5GAEW 3PIPS 2ZJRS 1EXDA 2ZJQS 4U67S 2HZ7A 4H4KA 5JVHS 5GAHW 1EUQA 4V194 3X1LB 1GTRA 5JVGS 4WCES 1ZJWA 1B75A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P2B A;  4IOC S;  1GTS A;  2ZJP S;  4JYZ A;  5IZN A;  1O0C A;  1QRT A;  3DLL S;  4IOA S;  5HL7 S;  4UY8 8;  3AII A;  2RD2 A;  5GAG W;  1QRU A;  4WFA S;  4WFB S;  4WFN S;  1EUY A;  3PIO S;  1DFU P;  1D6K A;  1QTQ A;  1NYL A;  1O0B A;  4IO9 S;  5GAD W;  1QRS A;  5DM6 S;  4WF9 S;  3J7Z V;  3CF5 S;  1FEU A;  4JXX A;  2RE8 A;  5DM7 S;  5BNZ A;  4JXZ A;  4H3S A;  5GAE W;  3PIP S;  2ZJR S;  1EXD A;  2ZJQ S;  4U67 S;  2HZ7 A;  5JVH S;  1EUQ A;  5GAH W;  1GTR A;  5JVG S;  4WCE S;  1ZJW A;  1B75 A; 
#chains in the Genus database with same CATH topology
 4P2B A;  4BBS C;  4IOC S;  2EGV A;  1GTS A;  2G5D A;  2KXY A;  1QRT A;  3HOX C;  4Y7N C;  4G7O A;  2R92 C;  5HL7 S;  1SFO C;  3AII A;  1HQM A;  1VHK A;  5FLM C;  4QIW D;  2NVX C;  3S16 C;  3W2V B;  1EUY A;  2Z0Y A;  3I4N C;  3S1R C;  3CQZ C;  4A3I C;  2GAE A;  4A3M C;  1YNJ A;  2EGW A;  3GTK C;  4NOI A;  4Y52 C;  4XLP A;  5IYD C;  5HQH A;  2NWA A;  1TWF C;  3RZD C;  3S1M C;  5BNZ A;  5GAE W;  3PIP S;  2ZJR S;  2PPB A;  1I3Q C;  1Y1V C;  2L3U A;  5TMF A;  3DXJ A;  2KQ1 A;  2PMZ D;  1EUQ A;  4C3J C;  4A3E C;  4J3C A;  1ZJW A;  1WCM C;  1TWA C;  3HKZ D;  2YU9 C;  4BY1 C;  2JA7 C;  2ZJP S;  4JYZ A;  5C44 C;  5IP7 C;  1O0C A;  4IOA S;  2VUM C;  2PIC A;  2PI8 A;  4LLG A;  4MQ9 A;  2NVQ C;  3HOW C;  2A69 A;  2O5J A;  5IYB C;  2A6E A;  4WFA S;  2CW0 A;  2Y0S D;  4YFN A;  4WFN S;  3GTJ C;  4BXX C;  3K7A C;  1Z85 A;  3PIO S;  1DFU P;  1IW7 A;  3FKI C;  4KMU A;  1VHY A;  4ZH4 A;  4YFX A;  4Q4Z A;  4A3F C;  1O0B A;  4A3J C;  4E8B A;  5GAD W;  1BDF A;  3LYW A;  4C3H C;  1V6Z A;  5DM6 S;  1TWC C;  4BBR C;  4KN7 A;  4WF9 S;  4MEX A;  3J7Z V;  1FEU A;  4LK1 A;  3GTP C;  3GTG C;  2A68 A;  2NVT C;  3S1N C;  4JK1 A;  5IYC C;  2A6H A;  1TWG C;  2JA8 C;  4A3D C;  1EXD A;  2WB1 D;  2PNW A;  3HOU C;  3RZO C;  3HOZ C;  3EQL A;  4A93 C;  3GTQ C;  5C4X C;  5GAH W;  3PO2 C;  5TMC A;  5C4J C;  4OIP A;  2E2H C;  3GTO C;  3S1Q C;  4OIQ A;  4GZY A;  3S17 C;  1ZYR A;  5IZN A;  5IP9 C;  3DLL S;  4LK0 A;  1UDX A;  4UY8 8;  2RD2 A;  1QRU A;  2E2J C;  5D4D A;  2B63 C;  4A3B C;  4BY7 C;  1YNN A;  2PJJ A;  1D6K A;  3H0G C;  4XLN A;  3CZB A;  2G6G A;  1NYL A;  4IO9 S;  2JA5 C;  1QRS A;  2KPU A;  4G7Z A;  1I6V A;  1R9T C;  4A3C C;  3S2D C;  5DM7 S;  3S14 C;  4YFK A;  4H3S A;  2L5N A;  4YG2 A;  3WOD A;  4XSZ A;  4QJV A;  4OIO A;  2ZJQ S;  4LJZ A;  4A3K C;  3M4O C;  4H4K A;  5JVH S;  2NVY C;  4A3G C;  1GTR A;  5JVG S;  4WCE S;  4XSX A;  1I6H C;  4X6A C;  4C3I C;  2PA8 D;  2BE5 A;  3S15 C;  5GAG W;  2AE0 X;  2CX8 A;  1NXZ A;  4WFB S;  3I4M C;  3S2H C;  4AYB D;  4C2M C;  1K83 C;  4OIR A;  1Y1W C;  3W2W B;  4L69 A;  1QTQ A;  1TWH C;  3GTM C;  4Q5S A;  1I50 C;  2R93 C;  3KW2 A;  3CF5 S;  1SMY A;  4JXX A;  2RE8 A;  4G7H A;  4OIN A;  4JXZ A;  3HOV C;  2JA6 C;  5C3E C;  2WAQ D;  4KN4 A;  4U67 S;  2E2I C;  2HZ7 A;  4V19 4;  3H3V D;  3HOY C;  3PO3 C;  3X1L B;  4A3L C;  2O5I A;  2R7Z C;  4MEY A;  1B75 A;  3GTL C;  3M3Y C; 
#chains in the Genus database with same CATH homology
 4P2B A;  4IOC S;  1GTS A;  2ZJP S;  4JYZ A;  5IZN A;  1O0C A;  1QRT A;  3DLL S;  4IOA S;  1UDX A;  5HL7 S;  4UY8 8;  3AII A;  2RD2 A;  5GAG W;  1QRU A;  4WFA S;  4WFB S;  3W2V B;  4WFN S;  1EUY A;  3PIO S;  1DFU P;  1D6K A;  3W2W B;  1QTQ A;  1NYL A;  1O0B A;  4IO9 S;  5GAD W;  1QRS A;  5DM6 S;  4WF9 S;  3J7Z V;  3CF5 S;  1FEU A;  4JXX A;  2RE8 A;  5DM7 S;  5BNZ A;  4JXZ A;  4H3S A;  5GAE W;  3PIP S;  2ZJR S;  1EXD A;  2ZJQ S;  4U67 S;  2HZ7 A;  4H4K A;  5JVH S;  5GAH W;  1EUQ A;  4V19 4;  3X1L B;  1GTR A;  5JVG S;  4WCE S;  1ZJW A;  1B75 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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