5HL7S

The crystal structure of the large ribosomal subunit of staphylococcus aureus in complex with lefamulin
Total Genus 22
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
167
structure length
167
Chain Sequence
SLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVDEVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTVEVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVKVTGDFKIEN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Ribosome
publication title A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism.
pubmed doi rcsb
molecule keywords 50S ribosomal protein L2
total genus 22
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2016-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5hl7S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5hl7S02
2RD2A 2ZJRS 1EUQA 4IOCS 2RE8A 1D6KA 1GTRA 1QRSA 4U67S 4WCES 3AIIA 1EXDA 5GAHW 2ZJPS 4IO9S 1GTSA 1QRUA 4WF9S 2HZ7A 5HL7S 1O0CA 5DM6S 5GAGW 4WFBS 1EUYA 5DM7S 5GAEW 4IOAS 5BNZA 3DLLS 5JVHS 4P2BA 1NYLA 5JVGS 1ZJWA 3J7ZV 1B75A 4WFAS 1QTQA 1DFUP 3PIOS 4H3SA 5GADW 3PIPS 3CF5S 1QRTA 4JXZA 4WFNS 1FEUA 1O0BA 4UY88 2ZJQS 5IZNA 4JXXA 4JYZA
chains in the Genus database with same CATH superfamily
2ZJRS 3W2WB 3M3YC 1GTRA 4KN4A 3S1QC 1QRSA 5IYCC 4GZYA 2E2HC 2PICA 4V194 3CQZC 4C2MC 3HOZC 3M4OC 4A3GC 4WCES 1I3QC 4BBRC 4J3CA 2NVQC 2EGVA 5TMFA 4NOIA 3GTPC 1TWGC 3HOVC 5D4DA 3S1NC 4G7OA 2L3UA 4A3MC 2O5IA 5DM7S 4A3JC 4G7ZA 1VHKA 3DLLS 1SMYA 2NVXC 1NYLA 5JVGS 1BDFA 2JA6C 4OIRA 3S2HC 4A3DC 2JA5C 1YNNA 2NVYC 5TMCA 1O0BA 1IW7A 4BY7C 1Z85A 3KW2A 2A6HA 1Y1WC 1VHYA 3S2DC 4C3JC 2PI8A 2JA8C 5IP7C 4Y52C 4QJVA 2YU9C 3GTLC 4OINA 3S1MC 3AIIA 3RZDC 4JK1A 5C4XC 1EXDA 2EGWA 1GTSA 4IO9S 2Y0SD 2R92C 4WF9S 2PA8D 2GAEA 2HZ7A 5HL7S 2E2IC 5DM6S 1TWHC 5GAGW 2KXYA 3GTQC 3S14C 3X1LB 3HKZD 4A3CC 2O5JA 4A3BC 2PNWA 1NXZA 4L69A 4A3IC 3HOYC 3S15C 2L5NA 2G5DA 1WCMC 2BE5A 4OIQA 4G7HA 3J7ZV 1QTQA 4H3SA 5GADW 2VUMC 4OIOA 1FEUA 2ZJQS 4JXXA 4H4KA 5HQHA 3H0GC 3I4MC 2RD2A 4YFXA 1EUQA 4IOCS 4C3HC 1D6KA 2R93C 4QIWD 2PMZD 4U67S 3WODA 3S17C 1SFOC 3GTJC 4MEXA 1V6ZA 2CW0A 4E8BA 4LK1A 5C3EC 2WB1D 4YFKA 4A93C 3S1RC 4BBSC 5FLMC 3HOUC 4X6AC 1QRUA 2KQ1A 4A3EC 4OIPA 3I4NC 1O0CA 4KMUA 2JA7C 3GTOC 3DXJA 1EUYA 2CX8A 1YNJA 5IYBC 3EQLA 5GAEW 4IOAS 5C44C 4MQ9A 5BNZA 1R9TC 2PPBA 3GTMC 4P2BA 4A3LC 1TWFC 3LYWA 3HOXC 2KPUA 1ZJWA 1B75A 4WFAS 2NWAA 1DFUP 3CF5S 1QRTA 2B63C 1I6HC 2AE0X 3CZBA 4YG2A 3PO2C 5IZNA 2R7ZC 3W2VB 1K83C 4JYZA 1TWAC 2PJJA 4LK0A 2A69A 4C3IC 4BY1C 2RE8A 4XSXA 3GTGC 1UDXA 1I6VA 4KN7A 3S16C 3FKIC 4A3FC 3GTKC 3H3VD 5GAHW 2ZJPS 3PO3C 2A68A 4BXXC 4XLPA 1I50C 4WFBS 5C4JC 4XSZA 2WAQD 1TWCC 1ZYRA 4A3KC 3HOWC 4Y7NC 1HQMA 5JVHS 2NVTC 4YFNA 2E2JC 3RZOC 4MEYA 4LJZA 4Q5SA 4Q4ZA 3PIOS 3PIPS 1Y1VC 4LLGA 4XLNA 4AYBD 2Z0YA 4WFNS 4JXZA 4ZH4A 5IYDC 4UY88 2A6EA 3K7AC 2G6GA 5IP9C
chains in the Genus database with same CATH topology
2RD2A 2ZJRS 1EUQA 3W2WB 4IOCS 2RE8A 1D6KA 1GTRA 1UDXA 4U67S 1QRSA 4V194 4WCES 3AIIA 1EXDA 5GAHW 2ZJPS 4IO9S 1GTSA 1QRUA 4WF9S 2HZ7A 5HL7S 1O0CA 5DM6S 5GAGW 4WFBS 1EUYA 3X1LB 5DM7S 5GAEW 4IOAS 5BNZA 3DLLS 5JVHS 4P2BA 1NYLA 5JVGS 1ZJWA 3J7ZV 1B75A 4WFAS 1QTQA 1DFUP 3PIOS 4H3SA 5GADW 3PIPS 3CF5S 1QRTA 4JXZA 4WFNS 1FEUA 1O0BA 4UY88 2ZJQS 5IZNA 4JXXA 4H4KA 3W2VB 4JYZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2RD2 A;  2ZJR S;  1EUQ A;  4IOC S;  2RE8 A;  1D6K A;  1GTR A;  1QRS A;  4U67 S;  4WCE S;  3AII A;  1EXD A;  5GAH W;  2ZJP S;  4IO9 S;  1GTS A;  1QRU A;  4WF9 S;  2HZ7 A;  5HL7 S;  1O0C A;  5DM6 S;  5GAG W;  4WFB S;  1EUY A;  5DM7 S;  5GAE W;  4IOA S;  5BNZ A;  3DLL S;  5JVH S;  4P2B A;  1NYL A;  5JVG S;  1ZJW A;  3J7Z V;  1B75 A;  4WFA S;  1QTQ A;  1DFU P;  3PIO S;  4H3S A;  5GAD W;  3PIP S;  3CF5 S;  1QRT A;  4JXZ A;  4WFN S;  1FEU A;  1O0B A;  4UY8 8;  2ZJQ S;  5IZN A;  4JXX A;  4JYZ A; 
#chains in the Genus database with same CATH topology
 2ZJR S;  3W2W B;  3M3Y C;  1GTR A;  4KN4 A;  3S1Q C;  1QRS A;  5IYC C;  4GZY A;  2E2H C;  2PIC A;  4V19 4;  3CQZ C;  4C2M C;  3HOZ C;  3M4O C;  4A3G C;  4WCE S;  1I3Q C;  4BBR C;  4J3C A;  2NVQ C;  2EGV A;  5TMF A;  4NOI A;  3GTP C;  1TWG C;  3HOV C;  5D4D A;  3S1N C;  4G7O A;  2L3U A;  4A3M C;  2O5I A;  5DM7 S;  4A3J C;  4G7Z A;  1VHK A;  3DLL S;  1SMY A;  2NVX C;  1NYL A;  5JVG S;  1BDF A;  2JA6 C;  4OIR A;  3S2H C;  4A3D C;  2JA5 C;  1YNN A;  2NVY C;  5TMC A;  1O0B A;  1IW7 A;  4BY7 C;  1Z85 A;  3KW2 A;  2A6H A;  1Y1W C;  1VHY A;  3S2D C;  4C3J C;  2PI8 A;  2JA8 C;  5IP7 C;  4Y52 C;  4QJV A;  2YU9 C;  3GTL C;  4OIN A;  3S1M C;  3AII A;  3RZD C;  4JK1 A;  5C4X C;  1EXD A;  2EGW A;  1GTS A;  4IO9 S;  2Y0S D;  2R92 C;  4WF9 S;  2PA8 D;  2GAE A;  2HZ7 A;  5HL7 S;  2E2I C;  5DM6 S;  1TWH C;  5GAG W;  2KXY A;  3GTQ C;  3S14 C;  3X1L B;  3HKZ D;  4A3C C;  2O5J A;  4A3B C;  2PNW A;  1NXZ A;  4L69 A;  4A3I C;  3HOY C;  3S15 C;  2L5N A;  2G5D A;  1WCM C;  2BE5 A;  4OIQ A;  4G7H A;  3J7Z V;  1QTQ A;  4H3S A;  5GAD W;  2VUM C;  4OIO A;  1FEU A;  2ZJQ S;  4JXX A;  4H4K A;  5HQH A;  3H0G C;  3I4M C;  2RD2 A;  4YFX A;  1EUQ A;  4IOC S;  4C3H C;  1D6K A;  2R93 C;  4QIW D;  2PMZ D;  4U67 S;  3WOD A;  3S17 C;  1SFO C;  3GTJ C;  4MEX A;  1V6Z A;  2CW0 A;  4E8B A;  4LK1 A;  5C3E C;  2WB1 D;  4YFK A;  4A93 C;  3S1R C;  4BBS C;  5FLM C;  3HOU C;  4X6A C;  1QRU A;  2KQ1 A;  4A3E C;  4OIP A;  3I4N C;  1O0C A;  4KMU A;  2JA7 C;  3GTO C;  3DXJ A;  1EUY A;  2CX8 A;  1YNJ A;  5IYB C;  3EQL A;  5GAE W;  4IOA S;  5C44 C;  4MQ9 A;  5BNZ A;  1R9T C;  2PPB A;  3GTM C;  4P2B A;  4A3L C;  1TWF C;  3LYW A;  3HOX C;  2KPU A;  1ZJW A;  1B75 A;  4WFA S;  2NWA A;  1DFU P;  3CF5 S;  1QRT A;  2B63 C;  1I6H C;  2AE0 X;  3CZB A;  4YG2 A;  3PO2 C;  5IZN A;  2R7Z C;  3W2V B;  1K83 C;  4JYZ A;  1TWA C;  2PJJ A;  4LK0 A;  2A69 A;  4C3I C;  4BY1 C;  2RE8 A;  4XSX A;  3GTG C;  1UDX A;  1I6V A;  4KN7 A;  3S16 C;  3FKI C;  4A3F C;  3GTK C;  3H3V D;  5GAH W;  2ZJP S;  3PO3 C;  2A68 A;  4BXX C;  4XLP A;  1I50 C;  4WFB S;  5C4J C;  4XSZ A;  2WAQ D;  1TWC C;  1ZYR A;  4A3K C;  3HOW C;  4Y7N C;  1HQM A;  5JVH S;  2NVT C;  4YFN A;  2E2J C;  3RZO C;  4MEY A;  4LJZ A;  4Q5S A;  4Q4Z A;  3PIO S;  3PIP S;  1Y1V C;  4LLG A;  4XLN A;  4AYB D;  2Z0Y A;  4WFN S;  4JXZ A;  4ZH4 A;  5IYD C;  4UY8 8;  2A6E A;  3K7A C;  2G6G A;  5IP9 C; 
#chains in the Genus database with same CATH homology
 2RD2 A;  2ZJR S;  1EUQ A;  3W2W B;  4IOC S;  2RE8 A;  1D6K A;  1GTR A;  1UDX A;  4U67 S;  1QRS A;  4V19 4;  4WCE S;  3AII A;  1EXD A;  5GAH W;  2ZJP S;  4IO9 S;  1GTS A;  1QRU A;  4WF9 S;  2HZ7 A;  5HL7 S;  1O0C A;  5DM6 S;  5GAG W;  4WFB S;  1EUY A;  3X1L B;  5DM7 S;  5GAE W;  4IOA S;  5BNZ A;  3DLL S;  5JVH S;  4P2B A;  1NYL A;  5JVG S;  1ZJW A;  3J7Z V;  1B75 A;  4WFA S;  1QTQ A;  1DFU P;  3PIO S;  4H3S A;  5GAD W;  3PIP S;  3CF5 S;  1QRT A;  4JXZ A;  4WFN S;  1FEU A;  1O0B A;  4UY8 8;  2ZJQ S;  5IZN A;  4JXX A;  4H4K A;  3W2V B;  4JYZ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...