5JVGS

The large ribosomal subunit from deinococcus radiodurans in complex with avilamycin
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
180
structure length
180
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPRLTAEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 14
structure length 180
sequence length 180
ec nomenclature
pdb deposition date 2016-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5jvgS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5jvgS02
3DLLS 2RE8A 4U67S 5HL7S 1QRTA 1EUQA 3CF5S 1O0BA 5GAHW 5GADW 3PIOS 5DM7S 4JXXA 5GAGW 3PIPS 4H3SA 1O0CA 2ZJRS 5IZNA 1NYLA 1B75A 5JVGS 4IO9S 1QRSA 5BNZA 1GTRA 4JXZA 1D6KA 2ZJPS 4WCES 4UY88 4WFBS 2HZ7A 1QRUA 4IOAS 4JYZA 4WFNS 1ZJWA 3AIIA 1DFUP 2RD2A 1QTQA 1FEUA 1GTSA 2ZJQS 4WF9S 4WFAS 3J7ZV 4IOCS 1EXDA 5JVHS 4P2BA 5DM6S 1EUYA 5GAEW
chains in the Genus database with same CATH superfamily
3HKZD 2NVTC 4YFNA 2PA8D 5IYBC 3GTKC 2PMZD 2EGWA 2R92C 1TWCC 2JA7C 3S1QC 3WODA 3HOYC 5C4JC 5GADW 2WB1D 5IP7C 3HOWC 5GAGW 3M4OC 3CZBA 4GZYA 4ZH4A 4A3KC 2G6GA 4JXZA 3GTQC 4A3CC 3S17C 4WCES 1R9TC 5IYCC 3GTOC 3S1NC 4A3LC 4A93C 2HZ7A 1Z85A 1QRUA 2BE5A 4KMUA 4YG2A 2E2HC 2JA5C 3GTJC 2NVYC 1DFUP 3M3YC 1QTQA 1FEUA 1HQMA 4LJZA 2ZJQS 4YFKA 1TWAC 2JA8C 4WFAS 2GAEA 2L3UA 2NVQC 3KW2A 1SMYA 1Y1WC 3S1MC 4OIQA 4A3FC 1YNJA 5HQHA 4U67S 3HOVC 1QRTA 1TWHC 4A3JC 4KN7A 4C2MC 5IYDC 5GAHW 3S1RC 5DM7S 1V6ZA 2PNWA 4JXXA 3EQLA 2AE0X 3S2HC 2R93C 4L69A 2YU9C 2PI8A 5IZNA 1VHYA 3X1LB 4C3JC 2WAQD 1TWGC 5TMFA 4Y52C 1SFOC 2A6EA 2ZJPS 4XLNA 3I4MC 2EGVA 2R7ZC 2PJJA 4WFBS 1I6HC 4XSXA 4G7OA 2CX8A 4BXXC 2B63C 4A3BC 2Z0YA 3PO3C 2E2JC 3S14C 4Y7NC 2RD2A 1I6VA 2NWAA 3J7ZV 4IOCS 2VUMC 4Q5SA 4A3DC 3GTGC 1I3QC 2KXYA 4OINA 1WCMC 4QJVA 1BDFA 4J3CA 4A3EC 3CF5S 3DXJA 4A3GC 2O5IA 3S2DC 5C4XC 2A69A 2Y0SD 3I4NC 3GTMC 4H3SA 1O0CA 2ZJRS 1NYLA 5IP9C 4A3IC 4OIOA 4OIRA 3HOXC 3GTLC 5BNZA 1GTRA 2CW0A 1D6KA 4E8BA 5D4DA 4AYBD 3W2WB 4LK0A 4LK1A 5C3EC 2G5DA 4MEYA 4OIPA 1TWFC 4QIWD 4IOAS 2A68A 4KN4A 2NVXC 1NXZA 2L5NA 3FKIC 3H3VD 4H4KA 4C3IC 2PPBA 1VHKA 4BBRC 1GTSA 4A3MC 1Y1VC 4WF9S 3S15C 4BY7C 1EXDA 3LYWA 4BY1C 4Q4ZA 1YNNA 3H0GC 5DM6S 2JA6C 5GAEW 4V194 3DLLS 2RE8A 1K83C 4LLGA 5HL7S 4XSZA 1EUQA 2E2IC 4G7HA 4X6AC 1O0BA 3PIOS 2A6HA 4BBSC 3PIPS 1ZYRA 5FLMC 2KPUA 4JK1A 1B75A 5TMCA 5JVGS 4IO9S 1QRSA 3RZOC 1IW7A 3W2VB 3PO2C 4UY88 3CQZC 4NOIA 2KQ1A 4JYZA 3K7AC 4YFXA 4WFNS 1ZJWA 2PICA 4C3HC 3AIIA 3HOUC 1UDXA 2O5JA 4MEXA 4G7ZA 3GTPC 1I50C 3S16C 3RZDC 5JVHS 4XLPA 3HOZC 4MQ9A 4P2BA 5C44C 1EUYA
chains in the Genus database with same CATH topology
4V194 3DLLS 2RE8A 4U67S 5HL7S 1QRTA 1EUQA 3CF5S 1O0BA 5GAHW 5GADW 3PIOS 5DM7S 4JXXA 5GAGW 3PIPS 4H3SA 1O0CA 2ZJRS 5IZNA 1NYLA 3X1LB 1B75A 5JVGS 4IO9S 1QRSA 3W2VB 5BNZA 1GTRA 1D6KA 2ZJPS 4JXZA 4WCES 3W2WB 4UY88 4WFBS 2HZ7A 1QRUA 4IOAS 4JYZA 4WFNS 1ZJWA 3AIIA 1UDXA 4H4KA 1DFUP 2RD2A 1QTQA 1FEUA 1GTSA 2ZJQS 4WF9S 4WFAS 3J7ZV 4IOCS 1EXDA 5JVHS 4P2BA 5DM6S 1EUYA 5GAEW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DLL S;  2RE8 A;  4U67 S;  5HL7 S;  1QRT A;  1EUQ A;  3CF5 S;  1O0B A;  5GAH W;  5GAD W;  3PIO S;  5DM7 S;  4JXX A;  5GAG W;  3PIP S;  4H3S A;  1O0C A;  2ZJR S;  5IZN A;  1NYL A;  1B75 A;  5JVG S;  4IO9 S;  1QRS A;  5BNZ A;  1GTR A;  4JXZ A;  1D6K A;  2ZJP S;  4WCE S;  4UY8 8;  4WFB S;  2HZ7 A;  1QRU A;  4IOA S;  4JYZ A;  4WFN S;  1ZJW A;  3AII A;  1DFU P;  2RD2 A;  1QTQ A;  1FEU A;  1GTS A;  2ZJQ S;  4WF9 S;  4WFA S;  3J7Z V;  4IOC S;  1EXD A;  5JVH S;  4P2B A;  5DM6 S;  1EUY A;  5GAE W; 
#chains in the Genus database with same CATH topology
 3HKZ D;  2NVT C;  4YFN A;  2PA8 D;  5IYB C;  3GTK C;  2PMZ D;  2EGW A;  2R92 C;  1TWC C;  2JA7 C;  3S1Q C;  3WOD A;  3HOY C;  5C4J C;  5GAD W;  2WB1 D;  5IP7 C;  3HOW C;  5GAG W;  3M4O C;  3CZB A;  4GZY A;  4ZH4 A;  4A3K C;  2G6G A;  4JXZ A;  3GTQ C;  4A3C C;  3S17 C;  4WCE S;  1R9T C;  5IYC C;  3GTO C;  3S1N C;  4A3L C;  4A93 C;  2HZ7 A;  1Z85 A;  1QRU A;  2BE5 A;  4KMU A;  4YG2 A;  2E2H C;  2JA5 C;  3GTJ C;  2NVY C;  1DFU P;  3M3Y C;  1QTQ A;  1FEU A;  1HQM A;  4LJZ A;  2ZJQ S;  4YFK A;  1TWA C;  2JA8 C;  4WFA S;  2GAE A;  2L3U A;  2NVQ C;  3KW2 A;  1SMY A;  1Y1W C;  3S1M C;  4OIQ A;  4A3F C;  1YNJ A;  5HQH A;  4U67 S;  3HOV C;  1QRT A;  1TWH C;  4A3J C;  4KN7 A;  4C2M C;  5IYD C;  5GAH W;  3S1R C;  5DM7 S;  1V6Z A;  2PNW A;  4JXX A;  3EQL A;  2AE0 X;  3S2H C;  2R93 C;  4L69 A;  2YU9 C;  2PI8 A;  5IZN A;  1VHY A;  3X1L B;  4C3J C;  2WAQ D;  1TWG C;  5TMF A;  4Y52 C;  1SFO C;  2A6E A;  2ZJP S;  4XLN A;  3I4M C;  2EGV A;  2R7Z C;  2PJJ A;  4WFB S;  1I6H C;  4XSX A;  4G7O A;  2CX8 A;  4BXX C;  2B63 C;  4A3B C;  2Z0Y A;  3PO3 C;  2E2J C;  3S14 C;  4Y7N C;  2RD2 A;  1I6V A;  2NWA A;  3J7Z V;  4IOC S;  2VUM C;  4Q5S A;  4A3D C;  3GTG C;  1I3Q C;  2KXY A;  4OIN A;  1WCM C;  4QJV A;  1BDF A;  4J3C A;  4A3E C;  3CF5 S;  3DXJ A;  4A3G C;  2O5I A;  3S2D C;  5C4X C;  2A69 A;  2Y0S D;  3I4N C;  3GTM C;  4H3S A;  1O0C A;  2ZJR S;  1NYL A;  5IP9 C;  4A3I C;  4OIO A;  4OIR A;  3HOX C;  3GTL C;  5BNZ A;  1GTR A;  2CW0 A;  1D6K A;  4E8B A;  5D4D A;  4AYB D;  3W2W B;  4LK0 A;  4LK1 A;  5C3E C;  2G5D A;  4MEY A;  4OIP A;  1TWF C;  4QIW D;  4IOA S;  2A68 A;  4KN4 A;  2NVX C;  1NXZ A;  2L5N A;  3FKI C;  3H3V D;  4H4K A;  4C3I C;  2PPB A;  1VHK A;  4BBR C;  1GTS A;  4A3M C;  1Y1V C;  4WF9 S;  3S15 C;  4BY7 C;  1EXD A;  3LYW A;  4BY1 C;  4Q4Z A;  1YNN A;  3H0G C;  5DM6 S;  2JA6 C;  5GAE W;  4V19 4;  3DLL S;  2RE8 A;  1K83 C;  4LLG A;  5HL7 S;  4XSZ A;  1EUQ A;  2E2I C;  4G7H A;  4X6A C;  1O0B A;  3PIO S;  2A6H A;  4BBS C;  3PIP S;  1ZYR A;  5FLM C;  2KPU A;  4JK1 A;  1B75 A;  5TMC A;  5JVG S;  4IO9 S;  1QRS A;  3RZO C;  1IW7 A;  3W2V B;  3PO2 C;  4UY8 8;  3CQZ C;  4NOI A;  2KQ1 A;  4JYZ A;  3K7A C;  4YFX A;  4WFN S;  1ZJW A;  2PIC A;  4C3H C;  3AII A;  3HOU C;  1UDX A;  2O5J A;  4MEX A;  4G7Z A;  3GTP C;  1I50 C;  3S16 C;  3RZD C;  5JVH S;  4XLP A;  3HOZ C;  4MQ9 A;  4P2B A;  5C44 C;  1EUY A; 
#chains in the Genus database with same CATH homology
 4V19 4;  3DLL S;  2RE8 A;  4U67 S;  5HL7 S;  1QRT A;  1EUQ A;  3CF5 S;  1O0B A;  5GAH W;  5GAD W;  3PIO S;  5DM7 S;  4JXX A;  5GAG W;  3PIP S;  4H3S A;  1O0C A;  2ZJR S;  5IZN A;  1NYL A;  3X1L B;  1B75 A;  5JVG S;  4IO9 S;  1QRS A;  3W2V B;  5BNZ A;  1GTR A;  1D6K A;  2ZJP S;  4JXZ A;  4WCE S;  3W2W B;  4UY8 8;  4WFB S;  2HZ7 A;  1QRU A;  4IOA S;  4JYZ A;  4WFN S;  1ZJW A;  3AII A;  1UDX A;  4H4K A;  1DFU P;  2RD2 A;  1QTQ A;  1FEU A;  1GTS A;  2ZJQ S;  4WF9 S;  4WFA S;  3J7Z V;  4IOC S;  1EXD A;  5JVH S;  4P2B A;  5DM6 S;  1EUY A;  5GAE W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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