5JVHS

The crystal structure large ribosomal subunit (50s) of deinococcus radiodurans in complex with evernimicin
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
179
structure length
179
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPRLTAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 19
structure length 179
sequence length 179
ec nomenclature
pdb deposition date 2016-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5jvhS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5jvhS02
5BNZA 1QTQA 1GTSA 4IO9S 1NYLA 4WFNS 5DM6S 3PIOS 5HL7S 4WFBS 4WCES 1EUYA 4JXZA 5GADW 3AIIA 5GAEW 4U67S 5DM7S 4JYZA 1QRTA 2RE8A 4WFAS 1EUQA 5GAGW 1EXDA 2RD2A 4JXXA 4P2BA 1B75A 1O0CA 3DLLS 4WF9S 4UY88 1D6KA 4H3SA 1GTRA 1O0BA 2ZJQS 3CF5S 2ZJRS 5JVGS 1QRUA 5GAHW 2ZJPS 1FEUA 5JVHS 4IOAS 1ZJWA 1QRSA 4IOCS 2HZ7A 5IZNA 1DFUP 3J7ZV 3PIPS
chains in the Genus database with same CATH superfamily
1Y1VC 2NVXC 2AE0X 4A3KC 4GZYA 4MEYA 3PIOS 2PJJA 4E8BA 1BDFA 4NOIA 2NVQC 3S1NC 2R93C 4A3LC 2PNWA 4Y52C 3CZBA 5HQHA 5C3EC 2E2JC 4LK0A 2RE8A 1EUQA 3GTOC 2JA8C 1HQMA 5GAGW 1EXDA 2KPUA 4LJZA 3GTPC 4LLGA 2Z0YA 1O0CA 3WODA 4H4KA 2Y0SD 1YNJA 2R7ZC 1O0BA 2ZJQS 1TWCC 2PI8A 3CF5S 3GTGC 3S14C 4A93C 3EQLA 2VUMC 5JVHS 1ZJWA 3GTMC 4IOCS 2E2HC 5IZNA 4A3GC 4X6AC 4OIRA 3GTLC 3FKIC 1QTQA 5D4DA 4XLPA 4IO9S 1NYLA 1IW7A 5C4JC 4A3JC 1I6HC 3I4MC 5IYDC 4BY1C 3K7AC 5DM7S 4MEXA 1Z85A 4JYZA 2KXYA 2E2IC 1QRTA 2JA7C 2G6GA 4LK1A 3HOVC 4C3HC 3HOWC 3S17C 4WFAS 2O5IA 4A3BC 3HOUC 3S1QC 1I6VA 2RD2A 4JXXA 3HOYC 2YU9C 2PA8D 5IP7C 1UDXA 4WF9S 3X1LB 5TMCA 2NVTC 1GTRA 2CX8A 4G7ZA 1SMYA 3DXJA 4KMUA 4XLNA 2ZJRS 1QRUA 1VHYA 4A3EC 2JA5C 2GAEA 3LYWA 2B63C 1Y1WC 3GTKC 2A69A 1FEUA 2G5DA 1WCMC 4Q5SA 1QRSA 4KN7A 2O5JA 1TWHC 1V6ZA 3J7ZV 4C2MC 4A3FC 5BNZA 2L3UA 1YNNA 2EGVA 2PMZD 3M3YC 1GTSA 1TWAC 4KN4A 4C3IC 4A3CC 3S16C 5HL7S 5IP9C 3I4NC 3AIIA 4OIPA 5GAEW 5IYCC 2WB1D 3PO2C 4MQ9A 3S2DC 4G7OA 3S15C 2BE5A 4C3JC 3GTJC 4J3CA 4V194 4YFKA 1R9TC 3H0GC 4P2BA 3HOZC 1B75A 5C4XC 4JK1A 4UY88 3HKZD 1D6KA 4QIWD 4A3IC 4Q4ZA 2CW0A 2NVYC 1K83C 5IYBC 4Y7NC 4OINA 4YG2A 3PO3C 4YFXA 1TWGC 4BY7C 2HZ7A 2R92C 1DFUP 4QJVA 3PIPS 2PPBA 5C44C 2KQ1A 4A3MC 4BBSC 3W2WB 1I3QC 3GTQC 4WFNS 5DM6S 1EUYA 4WFBS 4WCES 4JXZA 4OIOA 3RZDC 5GADW 2JA6C 4BXXC 3W2VB 4A3DC 4U67S 1TWFC 5FLMC 3S1RC 1ZYRA 4L69A 2WAQD 2L5NA 3S2HC 1NXZA 2A68A 3DLLS 5TMFA 1I50C 4G7HA 4OIQA 3H3VD 4H3SA 3CQZC 5JVGS 4AYBD 2EGWA 3HOXC 1SFOC 1VHKA 2A6HA 5GAHW 2PICA 4ZH4A 4XSXA 2ZJPS 3KW2A 4IOAS 3M4OC 4XSZA 3S1MC 4YFNA 4BBRC 3RZOC 2A6EA 2NWAA
chains in the Genus database with same CATH topology
5BNZA 3W2WB 1QTQA 1GTSA 4IO9S 1NYLA 4WFNS 5DM6S 3PIOS 5HL7S 4WFBS 4WCES 1EUYA 4JXZA 5GADW 3AIIA 3W2VB 5GAEW 5DM7S 4U67S 4JYZA 1QRTA 2RE8A 4V194 4WFAS 1EUQA 5GAGW 1EXDA 2RD2A 4JXXA 4P2BA 1B75A 1UDXA 1O0CA 4H4KA 3DLLS 4WF9S 3X1LB 4UY88 1D6KA 4H3SA 1GTRA 1O0BA 2ZJQS 3CF5S 2ZJRS 5JVGS 1QRUA 5GAHW 2ZJPS 1FEUA 5JVHS 4IOAS 1ZJWA 1QRSA 4IOCS 2HZ7A 5IZNA 1DFUP 3J7ZV 3PIPS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BNZ A;  1QTQ A;  1GTS A;  4IO9 S;  1NYL A;  4WFN S;  5DM6 S;  3PIO S;  5HL7 S;  4WFB S;  4WCE S;  1EUY A;  4JXZ A;  5GAD W;  3AII A;  5GAE W;  4U67 S;  5DM7 S;  4JYZ A;  1QRT A;  2RE8 A;  4WFA S;  1EUQ A;  5GAG W;  1EXD A;  2RD2 A;  4JXX A;  4P2B A;  1B75 A;  1O0C A;  3DLL S;  4WF9 S;  4UY8 8;  1D6K A;  4H3S A;  1GTR A;  1O0B A;  2ZJQ S;  3CF5 S;  2ZJR S;  5JVG S;  1QRU A;  5GAH W;  2ZJP S;  1FEU A;  5JVH S;  4IOA S;  1ZJW A;  1QRS A;  4IOC S;  2HZ7 A;  5IZN A;  1DFU P;  3J7Z V;  3PIP S; 
#chains in the Genus database with same CATH topology
 1Y1V C;  2NVX C;  2AE0 X;  4A3K C;  4GZY A;  4MEY A;  3PIO S;  2PJJ A;  4E8B A;  1BDF A;  4NOI A;  2NVQ C;  3S1N C;  2R93 C;  4A3L C;  2PNW A;  4Y52 C;  3CZB A;  5HQH A;  5C3E C;  2E2J C;  4LK0 A;  2RE8 A;  1EUQ A;  3GTO C;  2JA8 C;  1HQM A;  5GAG W;  1EXD A;  2KPU A;  4LJZ A;  3GTP C;  4LLG A;  2Z0Y A;  1O0C A;  3WOD A;  4H4K A;  2Y0S D;  1YNJ A;  2R7Z C;  1O0B A;  2ZJQ S;  1TWC C;  2PI8 A;  3CF5 S;  3GTG C;  3S14 C;  4A93 C;  3EQL A;  2VUM C;  5JVH S;  1ZJW A;  3GTM C;  4IOC S;  2E2H C;  5IZN A;  4A3G C;  4X6A C;  4OIR A;  3GTL C;  3FKI C;  1QTQ A;  5D4D A;  4XLP A;  4IO9 S;  1NYL A;  1IW7 A;  5C4J C;  4A3J C;  1I6H C;  3I4M C;  5IYD C;  4BY1 C;  3K7A C;  5DM7 S;  4MEX A;  1Z85 A;  4JYZ A;  2KXY A;  2E2I C;  1QRT A;  2JA7 C;  2G6G A;  4LK1 A;  3HOV C;  4C3H C;  3HOW C;  3S17 C;  4WFA S;  2O5I A;  4A3B C;  3HOU C;  3S1Q C;  1I6V A;  2RD2 A;  4JXX A;  3HOY C;  2YU9 C;  2PA8 D;  5IP7 C;  1UDX A;  4WF9 S;  3X1L B;  5TMC A;  2NVT C;  1GTR A;  2CX8 A;  4G7Z A;  1SMY A;  3DXJ A;  4KMU A;  4XLN A;  2ZJR S;  1QRU A;  1VHY A;  4A3E C;  2JA5 C;  2GAE A;  3LYW A;  2B63 C;  1Y1W C;  3GTK C;  2A69 A;  1FEU A;  2G5D A;  1WCM C;  4Q5S A;  1QRS A;  4KN7 A;  2O5J A;  1TWH C;  1V6Z A;  3J7Z V;  4C2M C;  4A3F C;  5BNZ A;  2L3U A;  1YNN A;  2EGV A;  2PMZ D;  3M3Y C;  1GTS A;  1TWA C;  4KN4 A;  4C3I C;  4A3C C;  3S16 C;  5HL7 S;  5IP9 C;  3I4N C;  3AII A;  4OIP A;  5GAE W;  5IYC C;  2WB1 D;  3PO2 C;  4MQ9 A;  3S2D C;  4G7O A;  3S15 C;  2BE5 A;  4C3J C;  3GTJ C;  4J3C A;  4V19 4;  4YFK A;  1R9T C;  3H0G C;  4P2B A;  3HOZ C;  1B75 A;  5C4X C;  4JK1 A;  4UY8 8;  3HKZ D;  1D6K A;  4QIW D;  4A3I C;  4Q4Z A;  2CW0 A;  2NVY C;  1K83 C;  5IYB C;  4Y7N C;  4OIN A;  4YG2 A;  3PO3 C;  4YFX A;  1TWG C;  4BY7 C;  2HZ7 A;  2R92 C;  1DFU P;  4QJV A;  3PIP S;  2PPB A;  5C44 C;  2KQ1 A;  4A3M C;  4BBS C;  3W2W B;  1I3Q C;  3GTQ C;  4WFN S;  5DM6 S;  1EUY A;  4WFB S;  4WCE S;  4JXZ A;  4OIO A;  3RZD C;  5GAD W;  2JA6 C;  4BXX C;  3W2V B;  4A3D C;  4U67 S;  1TWF C;  5FLM C;  3S1R C;  1ZYR A;  4L69 A;  2WAQ D;  2L5N A;  3S2H C;  1NXZ A;  2A68 A;  3DLL S;  5TMF A;  1I50 C;  4G7H A;  4OIQ A;  3H3V D;  4H3S A;  3CQZ C;  5JVG S;  4AYB D;  2EGW A;  3HOX C;  1SFO C;  1VHK A;  2A6H A;  5GAH W;  2PIC A;  4ZH4 A;  4XSX A;  2ZJP S;  3KW2 A;  4IOA S;  3M4O C;  4XSZ A;  3S1M C;  4YFN A;  4BBR C;  3RZO C;  2A6E A;  2NWA A; 
#chains in the Genus database with same CATH homology
 5BNZ A;  3W2W B;  1QTQ A;  1GTS A;  4IO9 S;  1NYL A;  4WFN S;  5DM6 S;  3PIO S;  5HL7 S;  4WFB S;  4WCE S;  1EUY A;  4JXZ A;  5GAD W;  3AII A;  3W2V B;  5GAE W;  5DM7 S;  4U67 S;  4JYZ A;  1QRT A;  2RE8 A;  4V19 4;  4WFA S;  1EUQ A;  5GAG W;  1EXD A;  2RD2 A;  4JXX A;  4P2B A;  1B75 A;  1UDX A;  1O0C A;  4H4K A;  3DLL S;  4WF9 S;  3X1L B;  4UY8 8;  1D6K A;  4H3S A;  1GTR A;  1O0B A;  2ZJQ S;  3CF5 S;  2ZJR S;  5JVG S;  1QRU A;  5GAH W;  2ZJP S;  1FEU A;  5JVH S;  4IOA S;  1ZJW A;  1QRS A;  4IOC S;  2HZ7 A;  5IZN A;  1DFU P;  3J7Z V;  3PIP S; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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