5JVHS

The crystal structure large ribosomal subunit (50s) of deinococcus radiodurans in complex with evernimicin
Total Genus 19
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
179
structure length
179
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPRLTAE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 23S ribosomal RNA
total genus 19
structure length 179
sequence length 179
ec nomenclature
pdb deposition date 2016-05-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5jvhS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5jvhS02
5GAHW 1GTRA 3AIIA 2RE8A 4JYZA 1B75A 3DLLS 1EXDA 3CF5S 5HL7S 3PIOS 1QRTA 5BNZA 4U67S 5GAEW 1D6KA 1EUYA 4WFAS 1GTSA 4H3SA 1ZJWA 4JXXA 1QTQA 1EUQA 3PIPS 1QRSA 3J7ZV 4WFNS 5GADW 5GAGW 2ZJQS 1O0BA 4IOAS 4IOCS 1FEUA 1QRUA 4P2BA 1DFUP 2RD2A 4WCES 4IO9S 2ZJPS 2ZJRS 4WF9S 4UY88 4WFBS 5JVHS 1O0CA 4JXZA 5DM7S 2HZ7A 1NYLA 5IZNA 5DM6S 5JVGS
chains in the Genus database with same CATH superfamily
4C3JC 1GTRA 1B75A 2AE0X 4G7OA 3LYWA 3DLLS 3PO2C 5IP9C 1VHYA 3CF5S 4A3LC 5HL7S 1QRTA 5BNZA 3M3YC 4U67S 5GAEW 1EUYA 1Z85A 4G7ZA 2EGWA 4Q4ZA 3I4MC 4V194 1TWCC 5IYDC 1I3QC 1SMYA 3HOVC 3HOWC 3HOXC 4A3CC 5GADW 5GAGW 2A69A 2E2HC 4LLGA 4JK1A 2PNWA 4OIPA 5HQHA 1FEUA 4P2BA 2RD2A 1HQMA 4WCES 2ZJPS 1YNNA 3S1QC 5TMCA 4UY88 2G6GA 1O0CA 1K83C 2L5NA 1Y1WC 5TMFA 5DM7S 3S15C 3FKIC 4E8BA 4A3KC 1SFOC 3H3VD 2KQ1A 2A6EA 3RZDC 4JYZA 2RE8A 4NOIA 1VHKA 1I6VA 4QJVA 3I4NC 3X1LB 3CQZC 2EGVA 3PIOS 4XSZA 3S16C 4LJZA 4Y7NC 5C4XC 4H4KA 2Y0SD 2GAEA 4KN4A 3S14C 3PIPS 3J7ZV 1I50C 4L69A 4XLPA 2G5DA 2ZJQS 3GTPC 1NXZA 4IOAS 2R93C 4BXXC 3HOZC 4C3HC 3W2VB 1UDXA 1V6ZA 2PICA 3CZBA 3H0GC 4IO9S 2PI8A 4X6AC 4WF9S 4WFBS 5JVHS 2NWAA 2NVTC 2NVYC 3S1MC 4BBSC 4OINA 2HZ7A 1NYLA 3S1RC 2O5IA 4J3CA 5IZNA 5DM6S 2PJJA 1I6HC 3GTGC 5GAHW 3W2WB 1R9TC 4AYBD 2O5JA 2JA5C 3HKZD 1EXDA 3EQLA 3GTOC 1WCMC 3KW2A 4BY7C 3GTJC 4KMUA 1YNJA 5C44C 2CW0A 4H3SA 2NVQC 1Y1VC 4XSXA 4A3FC 2KPUA 3M4OC 1TWAC 2PMZD 2YU9C 4QIWD 4C3IC 4WFNS 1O0BA 3DXJA 5IP7C 4Y52C 4XLNA 2WAQD 1QRUA 3WODA 4Q5SA 2E2IC 2Z0YA 2JA7C 1TWGC 4YFNA 4YFXA 2B63C 2L3UA 4C2MC 4LK1A 4ZH4A 5FLMC 2E2JC 4BY1C 2JA8C 2JA6C 3RZOC 4OIQA 4A3DC 4A3EC 3GTQC 3S17C 5JVGS 3HOYC 3HOUC 3AIIA 4MEXA 2BE5A 4LK0A 4GZYA 4G7HA 4A3BC 2A6HA 2PA8D 1GTSA 5D4DA 1D6KA 5C3EC 4WFAS 4A3IC 2VUMC 2R7ZC 1ZJWA 4YFKA 4JXXA 1QTQA 4KN7A 4A3JC 3GTKC 3GTMC 1EUQA 1QRSA 3S2HC 4MEYA 4A3GC 1IW7A 2PPBA 4A93C 3S2DC 4IOCS 3K7AC 3GTLC 1ZYRA 5IYCC 3PO3C 1DFUP 1TWFC 4MQ9A 2A68A 2ZJRS 2R92C 5C4JC 1TWHC 2NVXC 3S1NC 4JXZA 4BBRC 4OIOA 2KXYA 4A3MC 4OIRA 1BDFA 5IYBC 4YG2A 2WB1D 2CX8A
chains in the Genus database with same CATH topology
5GAHW 3W2WB 3AIIA 2RE8A 4JYZA 1GTRA 1B75A 3DLLS 1EXDA 3CF5S 5HL7S 3X1LB 3PIOS 1QRTA 5BNZA 4U67S 5GAEW 1D6KA 1EUYA 4WFAS 1GTSA 4H3SA 1ZJWA 4H4KA 4JXXA 1QTQA 4V194 1EUQA 3PIPS 1QRSA 3J7ZV 4WFNS 5GADW 5GAGW 2ZJQS 1O0BA 4IOAS 4IOCS 1FEUA 3W2VB 1UDXA 1QRUA 4P2BA 1DFUP 2RD2A 4WCES 4IO9S 2ZJPS 2ZJRS 4WF9S 4UY88 4WFBS 5JVHS 1O0CA 4JXZA 5DM7S 2HZ7A 1NYLA 5IZNA 5DM6S 5JVGS
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GAH W;  1GTR A;  3AII A;  2RE8 A;  4JYZ A;  1B75 A;  3DLL S;  1EXD A;  3CF5 S;  5HL7 S;  3PIO S;  1QRT A;  5BNZ A;  4U67 S;  5GAE W;  1D6K A;  1EUY A;  4WFA S;  1GTS A;  4H3S A;  1ZJW A;  4JXX A;  1QTQ A;  1EUQ A;  3PIP S;  1QRS A;  3J7Z V;  4WFN S;  5GAD W;  5GAG W;  2ZJQ S;  1O0B A;  4IOA S;  4IOC S;  1FEU A;  1QRU A;  4P2B A;  1DFU P;  2RD2 A;  4WCE S;  4IO9 S;  2ZJP S;  2ZJR S;  4WF9 S;  4UY8 8;  4WFB S;  5JVH S;  1O0C A;  4JXZ A;  5DM7 S;  2HZ7 A;  1NYL A;  5IZN A;  5DM6 S;  5JVG S; 
#chains in the Genus database with same CATH topology
 4C3J C;  1GTR A;  1B75 A;  2AE0 X;  4G7O A;  3LYW A;  3DLL S;  3PO2 C;  5IP9 C;  1VHY A;  3CF5 S;  4A3L C;  5HL7 S;  1QRT A;  5BNZ A;  3M3Y C;  4U67 S;  5GAE W;  1EUY A;  1Z85 A;  4G7Z A;  2EGW A;  4Q4Z A;  3I4M C;  4V19 4;  1TWC C;  5IYD C;  1I3Q C;  1SMY A;  3HOV C;  3HOW C;  3HOX C;  4A3C C;  5GAD W;  5GAG W;  2A69 A;  2E2H C;  4LLG A;  4JK1 A;  2PNW A;  4OIP A;  5HQH A;  1FEU A;  4P2B A;  2RD2 A;  1HQM A;  4WCE S;  2ZJP S;  1YNN A;  3S1Q C;  5TMC A;  4UY8 8;  2G6G A;  1O0C A;  1K83 C;  2L5N A;  1Y1W C;  5TMF A;  5DM7 S;  3S15 C;  3FKI C;  4E8B A;  4A3K C;  1SFO C;  3H3V D;  2KQ1 A;  2A6E A;  3RZD C;  4JYZ A;  2RE8 A;  4NOI A;  1VHK A;  1I6V A;  4QJV A;  3I4N C;  3X1L B;  3CQZ C;  2EGV A;  3PIO S;  4XSZ A;  3S16 C;  4LJZ A;  4Y7N C;  5C4X C;  4H4K A;  2Y0S D;  2GAE A;  4KN4 A;  3S14 C;  3PIP S;  3J7Z V;  1I50 C;  4L69 A;  4XLP A;  2G5D A;  2ZJQ S;  3GTP C;  1NXZ A;  4IOA S;  2R93 C;  4BXX C;  3HOZ C;  4C3H C;  3W2V B;  1UDX A;  1V6Z A;  2PIC A;  3CZB A;  3H0G C;  4IO9 S;  2PI8 A;  4X6A C;  4WF9 S;  4WFB S;  5JVH S;  2NWA A;  2NVT C;  2NVY C;  3S1M C;  4BBS C;  4OIN A;  2HZ7 A;  1NYL A;  3S1R C;  2O5I A;  4J3C A;  5IZN A;  5DM6 S;  2PJJ A;  1I6H C;  3GTG C;  5GAH W;  3W2W B;  1R9T C;  4AYB D;  2O5J A;  2JA5 C;  3HKZ D;  1EXD A;  3EQL A;  3GTO C;  1WCM C;  3KW2 A;  4BY7 C;  3GTJ C;  4KMU A;  1YNJ A;  5C44 C;  2CW0 A;  4H3S A;  2NVQ C;  1Y1V C;  4XSX A;  4A3F C;  2KPU A;  3M4O C;  1TWA C;  2PMZ D;  2YU9 C;  4QIW D;  4C3I C;  4WFN S;  1O0B A;  3DXJ A;  5IP7 C;  4Y52 C;  4XLN A;  2WAQ D;  1QRU A;  3WOD A;  4Q5S A;  2E2I C;  2Z0Y A;  2JA7 C;  1TWG C;  4YFN A;  4YFX A;  2B63 C;  2L3U A;  4C2M C;  4LK1 A;  4ZH4 A;  5FLM C;  2E2J C;  4BY1 C;  2JA8 C;  2JA6 C;  3RZO C;  4OIQ A;  4A3D C;  4A3E C;  3GTQ C;  3S17 C;  5JVG S;  3HOY C;  3HOU C;  3AII A;  4MEX A;  2BE5 A;  4LK0 A;  4GZY A;  4G7H A;  4A3B C;  2A6H A;  2PA8 D;  1GTS A;  5D4D A;  1D6K A;  5C3E C;  4WFA S;  4A3I C;  2VUM C;  2R7Z C;  1ZJW A;  4YFK A;  4JXX A;  1QTQ A;  4KN7 A;  4A3J C;  3GTK C;  3GTM C;  1EUQ A;  1QRS A;  3S2H C;  4MEY A;  4A3G C;  1IW7 A;  2PPB A;  4A93 C;  3S2D C;  4IOC S;  3K7A C;  3GTL C;  1ZYR A;  5IYC C;  3PO3 C;  1DFU P;  1TWF C;  4MQ9 A;  2A68 A;  2ZJR S;  2R92 C;  5C4J C;  1TWH C;  2NVX C;  3S1N C;  4JXZ A;  4BBR C;  4OIO A;  2KXY A;  4A3M C;  4OIR A;  1BDF A;  5IYB C;  4YG2 A;  2WB1 D;  2CX8 A; 
#chains in the Genus database with same CATH homology
 5GAH W;  3W2W B;  3AII A;  2RE8 A;  4JYZ A;  1GTR A;  1B75 A;  3DLL S;  1EXD A;  3CF5 S;  5HL7 S;  3X1L B;  3PIO S;  1QRT A;  5BNZ A;  4U67 S;  5GAE W;  1D6K A;  1EUY A;  4WFA S;  1GTS A;  4H3S A;  1ZJW A;  4H4K A;  4JXX A;  1QTQ A;  4V19 4;  1EUQ A;  3PIP S;  1QRS A;  3J7Z V;  4WFN S;  5GAD W;  5GAG W;  2ZJQ S;  1O0B A;  4IOA S;  4IOC S;  1FEU A;  3W2V B;  1UDX A;  1QRU A;  4P2B A;  1DFU P;  2RD2 A;  4WCE S;  4IO9 S;  2ZJP S;  2ZJR S;  4WF9 S;  4UY8 8;  4WFB S;  5JVH S;  1O0C A;  4JXZ A;  5DM7 S;  2HZ7 A;  1NYL A;  5IZN A;  5DM6 S;  5JVG S; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...