5DM7S

Crystal structure of the 50s ribosomal subunit from deinococcus radiodurans in complex with hygromycin a
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L1
total genus 19
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2015-09-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 5dm7S01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 5dm7S02
2ZJPS 4JYZA 1O0BA 4H3SA 3DLLS 4JXXA 1QRUA 1DFUP 4IOAS 4U67S 4WFAS 5GAHW 5GAEW 5DM6S 1QRTA 3CF5S 1NYLA 1GTRA 5JVGS 1GTSA 2ZJQS 1QTQA 4P2BA 1EUYA 1QRSA 2HZ7A 4WFBS 3J7ZV 4WF9S 2RD2A 5JVHS 2RE8A 5GAGW 1ZJWA 2ZJRS 4UY88 5BNZA 1FEUA 4JXZA 4IO9S 4IOCS 3PIPS 1EXDA 1B75A 4WFNS 1D6KA 1EUQA 3AIIA 5DM7S 5HL7S 4WCES 5IZNA 1O0CA 3PIOS 5GADW
chains in the Genus database with same CATH superfamily
2ZJPS 2E2HC 2E2IC 3I4MC 3S2DC 2PNWA 1DFUP 4NOIA 4G7HA 5IYBC 4IOAS 3S1RC 5IP9C 2VUMC 5IP7C 4WFAS 3M3YC 2PJJA 4KN4A 4Y52C 2NWAA 3GTOC 1K83C 1TWFC 3CQZC 3HOVC 4J3CA 4QJVA 4A3EC 4BBSC 2AE0X 1TWAC 2A6HA 2O5JA 3J7ZV 3W2VB 4C2MC 1TWCC 2R92C 5JVHS 2RE8A 1I3QC 4AYBD 4C3IC 1ZYRA 4A3JC 3GTLC 4G7OA 2WB1D 5TMFA 2R93C 1V6ZA 4IOCS 3PIPS 1B75A 3RZOC 1SMYA 3PO2C 3S15C 3S17C 1D6KA 2NVQC 3HKZD 3GTGC 5DM7S 4WCES 5IZNA 4BY7C 2KXYA 4C3JC 2KPUA 5TMCA 3HOYC 3EQLA 3CZBA 3I4NC 3KW2A 4A3DC 3H0GC 4Y7NC 4U67S 1BDFA 4OIPA 1QRTA 3DXJA 2EGVA 5C4JC 5HQHA 1SFOC 1NYLA 3H3VD 3PO3C 4E8BA 4LLGA 3GTMC 4LK0A 2L5NA 1YNNA 4MEXA 1QRSA 2HZ7A 4WFBS 4WF9S 4YG2A 4XLNA 3M4OC 4OIQA 1VHKA 5FLMC 2JA7C 5GAGW 1I6HC 4A3CC 4KN7A 1NXZA 5C4XC 4MQ9A 4Q5SA 3WODA 3HOWC 2CW0A 4YFXA 5C44C 3GTKC 2JA6C 2Z0YA 3LYWA 1I6VA 1Z85A 5HL7S 4C3HC 4L69A 4BY1C 3PIOS 4OINA 4A3MC 2PMZD 2B63C 4H3SA 4JXXA 4LK1A 1QRUA 1TWHC 4KMUA 3HOZC 2JA5C 2NVXC 3S16C 5GAEW 3HOUC 3W2WB 1GTRA 2G5DA 4A3FC 3S1QC 2ZJQS 1QTQA 2YU9C 3S14C 3HOXC 1EUYA 4YFKA 4V194 4XSZA 5IYCC 2RD2A 2PA8D 4QIWD 2L3UA 5C3EC 1Y1WC 2O5IA 3S2HC 5IYDC 4GZYA 2A6EA 1IW7A 4A3LC 5BNZA 2A68A 4JXZA 2NVYC 3GTJC 2PI8A 4IO9S 1R9TC 4A3GC 2EGWA 4WFNS 1EUQA 1Y1VC 4OIOA 3AIIA 4G7ZA 2GAEA 2WAQD 4JK1A 5GADW 3K7AC 3FKIC 1WCMC 4JYZA 1O0BA 4YFNA 4OIRA 3S1NC 2Y0SD 3DLLS 1TWGC 2CX8A 2BE5A 4BBRC 4X6AC 2JA8C 4MEYA 5GAHW 5DM6S 3CF5S 4XSXA 1HQMA 1UDXA 2G6GA 5JVGS 4ZH4A 1GTSA 3S1MC 3RZDC 4P2BA 5D4DA 4XLPA 3X1LB 2A69A 2NVTC 4A3KC 4A93C 1ZJWA 2ZJRS 1YNJA 3GTPC 4A3BC 1FEUA 4H4KA 2KQ1A 2E2JC 1EXDA 3GTQC 2R7ZC 1I50C 4LJZA 4A3IC 4Q4ZA 4BXXC 1VHYA 1O0CA 2PICA 4UY88 2PPBA
chains in the Genus database with same CATH topology
2ZJPS 4JYZA 1O0BA 4H3SA 3DLLS 4JXXA 1QRUA 1DFUP 4IOAS 4U67S 5GAHW 5GAEW 5DM6S 3W2WB 4WFAS 3CF5S 1NYLA 1GTRA 1QRTA 1UDXA 5JVGS 1GTSA 2ZJQS 1QTQA 4P2BA 1EUYA 1QRSA 2HZ7A 4WFBS 3J7ZV 3W2VB 4V194 3X1LB 4WF9S 2RD2A 5JVHS 2RE8A 5GAGW 1ZJWA 2ZJRS 4UY88 5BNZA 1FEUA 4JXZA 4H4KA 4IO9S 4IOCS 3PIPS 1EXDA 1B75A 4WFNS 1D6KA 1EUQA 3AIIA 5DM7S 5HL7S 4WCES 5IZNA 1O0CA 3PIOS 5GADW
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJP S;  4JYZ A;  1O0B A;  4H3S A;  3DLL S;  4JXX A;  1QRU A;  1DFU P;  4IOA S;  4U67 S;  4WFA S;  5GAH W;  5GAE W;  5DM6 S;  1QRT A;  3CF5 S;  1NYL A;  1GTR A;  5JVG S;  1GTS A;  2ZJQ S;  1QTQ A;  4P2B A;  1EUY A;  1QRS A;  2HZ7 A;  4WFB S;  3J7Z V;  4WF9 S;  2RD2 A;  5JVH S;  2RE8 A;  5GAG W;  1ZJW A;  2ZJR S;  4UY8 8;  5BNZ A;  1FEU A;  4JXZ A;  4IO9 S;  4IOC S;  3PIP S;  1EXD A;  1B75 A;  4WFN S;  1D6K A;  1EUQ A;  3AII A;  5DM7 S;  5HL7 S;  4WCE S;  5IZN A;  1O0C A;  3PIO S;  5GAD W; 
#chains in the Genus database with same CATH topology
 2ZJP S;  2E2H C;  2E2I C;  3I4M C;  3S2D C;  2PNW A;  1DFU P;  4NOI A;  4G7H A;  5IYB C;  4IOA S;  3S1R C;  5IP9 C;  2VUM C;  5IP7 C;  4WFA S;  3M3Y C;  2PJJ A;  4KN4 A;  4Y52 C;  2NWA A;  3GTO C;  1K83 C;  1TWF C;  3CQZ C;  3HOV C;  4J3C A;  4QJV A;  4A3E C;  4BBS C;  2AE0 X;  1TWA C;  2A6H A;  2O5J A;  3J7Z V;  3W2V B;  4C2M C;  1TWC C;  2R92 C;  5JVH S;  2RE8 A;  1I3Q C;  4AYB D;  4C3I C;  1ZYR A;  4A3J C;  3GTL C;  4G7O A;  2WB1 D;  5TMF A;  2R93 C;  1V6Z A;  4IOC S;  3PIP S;  1B75 A;  3RZO C;  1SMY A;  3PO2 C;  3S15 C;  3S17 C;  1D6K A;  2NVQ C;  3HKZ D;  3GTG C;  5DM7 S;  4WCE S;  5IZN A;  4BY7 C;  2KXY A;  4C3J C;  2KPU A;  5TMC A;  3HOY C;  3EQL A;  3CZB A;  3I4N C;  3KW2 A;  4A3D C;  3H0G C;  4Y7N C;  4U67 S;  1BDF A;  4OIP A;  1QRT A;  3DXJ A;  2EGV A;  5C4J C;  5HQH A;  1SFO C;  1NYL A;  3H3V D;  3PO3 C;  4E8B A;  4LLG A;  3GTM C;  4LK0 A;  2L5N A;  1YNN A;  4MEX A;  1QRS A;  2HZ7 A;  4WFB S;  4WF9 S;  4YG2 A;  4XLN A;  3M4O C;  4OIQ A;  1VHK A;  5FLM C;  2JA7 C;  5GAG W;  1I6H C;  4A3C C;  4KN7 A;  1NXZ A;  5C4X C;  4MQ9 A;  4Q5S A;  3WOD A;  3HOW C;  2CW0 A;  4YFX A;  5C44 C;  3GTK C;  2JA6 C;  2Z0Y A;  3LYW A;  1I6V A;  1Z85 A;  5HL7 S;  4C3H C;  4L69 A;  4BY1 C;  3PIO S;  4OIN A;  4A3M C;  2PMZ D;  2B63 C;  4H3S A;  4JXX A;  4LK1 A;  1QRU A;  1TWH C;  4KMU A;  3HOZ C;  2JA5 C;  2NVX C;  3S16 C;  5GAE W;  3HOU C;  3W2W B;  1GTR A;  2G5D A;  4A3F C;  3S1Q C;  2ZJQ S;  1QTQ A;  2YU9 C;  3S14 C;  3HOX C;  1EUY A;  4YFK A;  4V19 4;  4XSZ A;  5IYC C;  2RD2 A;  2PA8 D;  4QIW D;  2L3U A;  5C3E C;  1Y1W C;  2O5I A;  3S2H C;  5IYD C;  4GZY A;  2A6E A;  1IW7 A;  4A3L C;  5BNZ A;  2A68 A;  4JXZ A;  2NVY C;  3GTJ C;  2PI8 A;  4IO9 S;  1R9T C;  4A3G C;  2EGW A;  4WFN S;  1EUQ A;  1Y1V C;  4OIO A;  3AII A;  4G7Z A;  2GAE A;  2WAQ D;  4JK1 A;  5GAD W;  3K7A C;  3FKI C;  1WCM C;  4JYZ A;  1O0B A;  4YFN A;  4OIR A;  3S1N C;  2Y0S D;  3DLL S;  1TWG C;  2CX8 A;  2BE5 A;  4BBR C;  4X6A C;  2JA8 C;  4MEY A;  5GAH W;  5DM6 S;  3CF5 S;  4XSX A;  1HQM A;  1UDX A;  2G6G A;  5JVG S;  4ZH4 A;  1GTS A;  3S1M C;  3RZD C;  4P2B A;  5D4D A;  4XLP A;  3X1L B;  2A69 A;  2NVT C;  4A3K C;  4A93 C;  1ZJW A;  2ZJR S;  1YNJ A;  3GTP C;  4A3B C;  1FEU A;  4H4K A;  2KQ1 A;  2E2J C;  1EXD A;  3GTQ C;  2R7Z C;  1I50 C;  4LJZ A;  4A3I C;  4Q4Z A;  4BXX C;  1VHY A;  1O0C A;  2PIC A;  4UY8 8;  2PPB A; 
#chains in the Genus database with same CATH homology
 2ZJP S;  4JYZ A;  1O0B A;  4H3S A;  3DLL S;  4JXX A;  1QRU A;  1DFU P;  4IOA S;  4U67 S;  5GAH W;  5GAE W;  5DM6 S;  3W2W B;  4WFA S;  3CF5 S;  1NYL A;  1GTR A;  1QRT A;  1UDX A;  5JVG S;  1GTS A;  2ZJQ S;  1QTQ A;  4P2B A;  1EUY A;  1QRS A;  2HZ7 A;  4WFB S;  3J7Z V;  3W2V B;  4V19 4;  3X1L B;  4WF9 S;  2RD2 A;  5JVH S;  2RE8 A;  5GAG W;  1ZJW A;  2ZJR S;  4UY8 8;  5BNZ A;  1FEU A;  4JXZ A;  4H4K A;  4IO9 S;  4IOC S;  3PIP S;  1EXD A;  1B75 A;  4WFN S;  1D6K A;  1EUQ A;  3AII A;  5DM7 S;  5HL7 S;  4WCE S;  5IZN A;  1O0C A;  3PIO S;  5GAD W; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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