1W27A

Phenylalanine ammonia-lyase (pal) from petroselinum crispum
Total Genus 254
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
254
sequence length
690
structure length
689
Chain Sequence
EDPLYWGIAAEAMTGSHLDEVKKMVAEYRKPVVKLGGETLTISQVAAISARDGSGVTVELSEAARAGVKASSDWVMDSMNKGTDSYGVTTGFGATSHRRTKQGGALQKELIRFLNAGIFGNGSDNTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKFLNQNITPCLPLRGTITDLVPLSYIAGLLTGRPNSKAVGPTGVILSPEEAFKLAGVEGGFFELQPKEGLALVNGTAVGSGMASMVLFEANILAVLAEVMSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSAYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRSSTKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLAIAAIGKLMFAQFSELVNDFYNNGLPSNLSGGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISSRKTSEAVEILKLMSTTFLVGLCQAIDLRHLEENLKSTVKNTVSSVAKRVLTMGVNGELHPSRFCEKDLLRVVDREYIFAYIDDPCSATYPLMQKLRQTLVEHALKNGDNERNLSTSIFQKIATFEDELKALLPKEVESARAALESGNPAIPNRIEECRSYPLYKFVRKELGTEYLTGEKVTSPGEEFEKVFIAMSKGEIIDPLLECLESWNGAPLPIC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for the Entrance Into the Phenylpropanoid Metabolism Catalyzed by Phenylalanine Ammonia-Lyase
pubmed doi rcsb
molecule tags Lyase
source organism Petroselinum crispum
molecule keywords PHENYLALANINE AMMONIA-LYASE 1
total genus 254
structure length 689
sequence length 690
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2004-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 1w27A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 1w27A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 1w27A02
2PTRA 5F91A 4APAA 3OCFA 1HY1A 2PTSA 1U15A 3NZ4A 3E04A 3RRPA 1FUOA 2VD6A 5EYTA 3R6QA 1DCNA 4APBA 2YIIA 4EEIA 2QVEA 1TJUA 4BAAA 1EB4A 3QBPA 4V2RA 5F92A 1Q5NA 2NYNA 1T6JA 2OHYA 3R6YA 1K7WA 1TJWA 1TJ7A 2HVGA 3NO9A 3OCEA 1DOFA 3GTDA 1FUQA 3KDYA 1AUWA 2RJSA 2O6YA 1YFEA 2O7DA 3CZOA 1HY0A 1KQ7A 4FFXA 1K62A 4V2QA 5EYVA 2E9FA 1T6PA 1TJVA 2FUSA 1YFMA 2J91A 3BHGA 1FUPA 5D6BA 3RD8A 2PTQA 1Y2MA 1VDKA 4BABA 4ADLA 1XWOA 2QGAB 3GZHA 3R6VA 5HW2A 4C6GA 1GK3A 3KDZA 2O7FA 1I0AA 1U16A 4ADMA 1GK2A 1YISA 2NYFA 3UNVA 1RE5A 2RJRA 3C8TA 2PFMA 1C3CA 4CQ5A 1W27A 4C5UA 4C5SA 4FLCA 2O7BA 1C3UA 4NSLA 3TV2A 4HGVA 2X75A 2O78A 4C5RA 4NLEA 2O7EA 1B8FA 4MX2A 1FURA 1J3UA 1JSWA 1GKMA 1GKJA 4EFCA
chains in the Genus database with same CATH superfamily
2EZBA 2PTRA 3GTPA 5F91A 2A6HD 4APAA 2FIOA 2LKMB 1HY1A 3OCFA 2PTSA 1U15A 1Y1WA 2JA7A 3NZ4A 1IW7D 2R7ZA 3E04A 1R9TA 2K3NA 3RRPA 1XL8A 1FUOA 2NVYA 5M0JA 2B63A 3CRW1 2VD6A 3LR8A 1EZBA 2E2HA 1XMCA 5EYTA 5IZ2A 3R6QA 1DCNA 3GTQA 4APBA 2YIIA 4EEIA 2QVEA 1TJUA 4BAAA 1EB4A 2F5JA 3QBPA 3LR2A 1SMYD 4V2RA 5F92A 2EZAA 1TWAA 1Q5NA 2NYNA 1T6JA 3GTMA 2OHYA 2K3OA 3R6YA 1K7WA 2YU9A 1TJWA 2FENA 2JA5A 1TJ7A 2HVGA 3NO9A 3OCEA 1DOFA 4CEJA 3EZAA 3GTKA 2R93A 3CRVA 3CQZA 3GTDA 1FUQA 1TWCA 2Y0NA 2MQAA 3LR6A 3U4QA 2X0QA 1EZAA 1XMDA 1I3QA 1XL7A 3KDYA 1AUWA 4FBSA 2RJSA 2O6YA 1YFEA 2HWGA 2O7DA 2HROA 3FKIA 4QIWA 1HY0A 3CZOA 1KQ7A 4FFXA 1K62A 1K83A 4V2QA 1HQMD 1WCMA 2E9FA 5EYVA 1T6PA 1TJVA 2FUSA 1YFMA 3GTLA 2J91A 3BHGA 1FUPA 5D6BA 3RD8A 2PTQA 1Y2MA 2LPJA 2JA6A 1XLYA 2X0OA 1I50A 1TWGA 1VDKA 2A68D 3LRDA 4CEIA 4BABA 3EZBA 2O5JD 4ADLA 2A69D 3GTOA 1XWOA 2QGAB 3GZHA 3R6VA 5HW2A 4C6GA 1GK3A 2MX9A 3KDZA 4C2MA 3GTJA 2O7FA 1I0AA 2MX8A 1ZYMA 1U16A 4ADMA 3EZEA 1GK2A 2MP0A 5H8WA 1YNND 1YISA 4CEHA 1TWHA 2FELA 2LYIA 2X0PA 2FIPA 2NYFA 1RE5A 2BE5D 3UNVA 4A15A 2RJRA 2A6ED 1TWFA 2VUMA 2VL7A 3C8TA 3U44A 2CW0D 2PFMA 2AQLA 1C3CA 4CQ5A 1W27A 1I6VD 2E2IA 2N1DB 4C5UA 4C5SA 2R92A 4FLCA 1SFOA 2VSFA 2O7BA 1C3UA 4NSLA 3TV2A 2N3EA 5M0IA 3GTGA 4HGVA 2EZCA 3H0GA 2K3QA 2VK9A 2X75A 2LTHA 2NVXA 4C5RA 2O78A 4NLEA 1YNJD 2O7EA 1B8FA 4MX2A 4WNLA 1FURA 2LPIA 1J3UA 1JSWA 1GKMA 1Y1VA 1GKJA 4EFCA 1ZYRD
chains in the Genus database with same CATH topology
2PTRA 5F91A 4APAA 3OCFA 1HY1A 2PTSA 1U15A 3NZ4A 3E04A 3RRPA 1FUOA 2VD6A 5EYTA 3R6QA 1DCNA 4APBA 2YIIA 4EEIA 2QVEA 1TJUA 4BAAA 1EB4A 3QBPA 4V2RA 5F92A 1Q5NA 2NYNA 1T6JA 2OHYA 3R6YA 1K7WA 1TJWA 1TJ7A 2HVGA 3NO9A 3OCEA 1DOFA 3GTDA 1FUQA 3KDYA 1AUWA 2RJSA 2O6YA 1YFEA 2O7DA 3CZOA 1HY0A 1KQ7A 4FFXA 1K62A 4V2QA 5EYVA 2E9FA 1T6PA 1TJVA 2FUSA 1YFMA 2J91A 3BHGA 1FUPA 5D6BA 3RD8A 2PTQA 1Y2MA 1VDKA 4BABA 4ADLA 1XWOA 2QGAB 3GZHA 3R6VA 5HW2A 4C6GA 1GK3A 3KDZA 2O7FA 1I0AA 1U16A 4ADMA 1GK2A 1YISA 2NYFA 3UNVA 1RE5A 2RJRA 3C8TA 2PFMA 1C3CA 4CQ5A 1W27A 4C5UA 4C5SA 4FLCA 2O7BA 1C3UA 4NSLA 3TV2A 4HGVA 2X75A 2O78A 4C5RA 4NLEA 2O7EA 1B8FA 4MX2A 1FURA 1J3UA 1JSWA 1GKMA 1GKJA 4EFCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PTR A;  5F91 A;  4APA A;  3OCF A;  1HY1 A;  2PTS A;  1U15 A;  3NZ4 A;  3E04 A;  3RRP A;  1FUO A;  2VD6 A;  5EYT A;  3R6Q A;  1DCN A;  4APB A;  2YII A;  4EEI A;  2QVE A;  1TJU A;  4BAA A;  1EB4 A;  3QBP A;  4V2R A;  5F92 A;  1Q5N A;  2NYN A;  1T6J A;  2OHY A;  3R6Y A;  1K7W A;  1TJW A;  1TJ7 A;  2HVG A;  3NO9 A;  3OCE A;  1DOF A;  3GTD A;  1FUQ A;  3KDY A;  1AUW A;  2RJS A;  2O6Y A;  1YFE A;  2O7D A;  3CZO A;  1HY0 A;  1KQ7 A;  4FFX A;  1K62 A;  4V2Q A;  5EYV A;  2E9F A;  1T6P A;  1TJV A;  2FUS A;  1YFM A;  2J91 A;  3BHG A;  1FUP A;  5D6B A;  3RD8 A;  2PTQ A;  1Y2M A;  1VDK A;  4BAB A;  4ADL A;  1XWO A;  2QGA B;  3GZH A;  3R6V A;  5HW2 A;  4C6G A;  1GK3 A;  3KDZ A;  2O7F A;  1I0A A;  1U16 A;  4ADM A;  1GK2 A;  1YIS A;  2NYF A;  3UNV A;  1RE5 A;  2RJR A;  3C8T A;  2PFM A;  1C3C A;  4CQ5 A;  1W27 A;  4C5U A;  4C5S A;  4FLC A;  2O7B A;  1C3U A;  4NSL A;  3TV2 A;  4HGV A;  2X75 A;  2O78 A;  4C5R A;  4NLE A;  2O7E A;  1B8F A;  4MX2 A;  1FUR A;  1J3U A;  1JSW A;  1GKM A;  1GKJ A;  4EFC A; 
#chains in the Genus database with same CATH topology
 2EZB A;  2PTR A;  3GTP A;  5F91 A;  2A6H D;  4APA A;  2FIO A;  2LKM B;  1HY1 A;  3OCF A;  2PTS A;  1U15 A;  1Y1W A;  2JA7 A;  3NZ4 A;  1IW7 D;  2R7Z A;  3E04 A;  1R9T A;  2K3N A;  3RRP A;  1XL8 A;  1FUO A;  2NVY A;  5M0J A;  2B63 A;  3CRW 1;  2VD6 A;  3LR8 A;  1EZB A;  2E2H A;  1XMC A;  5EYT A;  5IZ2 A;  3R6Q A;  1DCN A;  3GTQ A;  4APB A;  2YII A;  4EEI A;  2QVE A;  1TJU A;  4BAA A;  1EB4 A;  2F5J A;  3QBP A;  3LR2 A;  1SMY D;  4V2R A;  5F92 A;  2EZA A;  1TWA A;  1Q5N A;  2NYN A;  1T6J A;  3GTM A;  2OHY A;  2K3O A;  3R6Y A;  1K7W A;  2YU9 A;  1TJW A;  2FEN A;  2JA5 A;  1TJ7 A;  2HVG A;  3NO9 A;  3OCE A;  1DOF A;  4CEJ A;  3EZA A;  3GTK A;  2R93 A;  3CRV A;  3CQZ A;  3GTD A;  1FUQ A;  1TWC A;  2Y0N A;  2MQA A;  3LR6 A;  3U4Q A;  2X0Q A;  1EZA A;  1XMD A;  1I3Q A;  1XL7 A;  3KDY A;  1AUW A;  4FBS A;  2RJS A;  2O6Y A;  1YFE A;  2HWG A;  2O7D A;  2HRO A;  3FKI A;  4QIW A;  1HY0 A;  3CZO A;  1KQ7 A;  4FFX A;  1K62 A;  1K83 A;  4V2Q A;  1HQM D;  1WCM A;  2E9F A;  5EYV A;  1T6P A;  1TJV A;  2FUS A;  1YFM A;  3GTL A;  2J91 A;  3BHG A;  1FUP A;  5D6B A;  3RD8 A;  2PTQ A;  1Y2M A;  2LPJ A;  2JA6 A;  1XLY A;  2X0O A;  1I50 A;  1TWG A;  1VDK A;  2A68 D;  3LRD A;  4CEI A;  4BAB A;  3EZB A;  2O5J D;  4ADL A;  2A69 D;  3GTO A;  1XWO A;  2QGA B;  3GZH A;  3R6V A;  5HW2 A;  4C6G A;  1GK3 A;  2MX9 A;  3KDZ A;  4C2M A;  3GTJ A;  2O7F A;  1I0A A;  2MX8 A;  1ZYM A;  1U16 A;  4ADM A;  3EZE A;  1GK2 A;  2MP0 A;  5H8W A;  1YNN D;  1YIS A;  4CEH A;  1TWH A;  2FEL A;  2LYI A;  2X0P A;  2FIP A;  2NYF A;  1RE5 A;  2BE5 D;  3UNV A;  4A15 A;  2RJR A;  2A6E D;  1TWF A;  2VUM A;  2VL7 A;  3C8T A;  3U44 A;  2CW0 D;  2PFM A;  2AQL A;  1C3C A;  4CQ5 A;  1W27 A;  1I6V D;  2E2I A;  2N1D B;  4C5U A;  4C5S A;  2R92 A;  4FLC A;  1SFO A;  2VSF A;  2O7B A;  1C3U A;  4NSL A;  3TV2 A;  2N3E A;  5M0I A;  3GTG A;  4HGV A;  2EZC A;  3H0G A;  2K3Q A;  2VK9 A;  2X75 A;  2LTH A;  2NVX A;  4C5R A;  2O78 A;  4NLE A;  1YNJ D;  2O7E A;  1B8F A;  4MX2 A;  4WNL A;  1FUR A;  2LPI A;  1J3U A;  1JSW A;  1GKM A;  1Y1V A;  1GKJ A;  4EFC A;  1ZYR D; 
#chains in the Genus database with same CATH homology
 2PTR A;  5F91 A;  4APA A;  3OCF A;  1HY1 A;  2PTS A;  1U15 A;  3NZ4 A;  3E04 A;  3RRP A;  1FUO A;  2VD6 A;  5EYT A;  3R6Q A;  1DCN A;  4APB A;  2YII A;  4EEI A;  2QVE A;  1TJU A;  4BAA A;  1EB4 A;  3QBP A;  4V2R A;  5F92 A;  1Q5N A;  2NYN A;  1T6J A;  2OHY A;  3R6Y A;  1K7W A;  1TJW A;  1TJ7 A;  2HVG A;  3NO9 A;  3OCE A;  1DOF A;  3GTD A;  1FUQ A;  3KDY A;  1AUW A;  2RJS A;  2O6Y A;  1YFE A;  2O7D A;  3CZO A;  1HY0 A;  1KQ7 A;  4FFX A;  1K62 A;  4V2Q A;  5EYV A;  2E9F A;  1T6P A;  1TJV A;  2FUS A;  1YFM A;  2J91 A;  3BHG A;  1FUP A;  5D6B A;  3RD8 A;  2PTQ A;  1Y2M A;  1VDK A;  4BAB A;  4ADL A;  1XWO A;  2QGA B;  3GZH A;  3R6V A;  5HW2 A;  4C6G A;  1GK3 A;  3KDZ A;  2O7F A;  1I0A A;  1U16 A;  4ADM A;  1GK2 A;  1YIS A;  2NYF A;  3UNV A;  1RE5 A;  2RJR A;  3C8T A;  2PFM A;  1C3C A;  4CQ5 A;  1W27 A;  4C5U A;  4C5S A;  4FLC A;  2O7B A;  1C3U A;  4NSL A;  3TV2 A;  4HGV A;  2X75 A;  2O78 A;  4C5R A;  4NLE A;  2O7E A;  1B8F A;  4MX2 A;  1FUR A;  1J3U A;  1JSW A;  1GKM A;  1GKJ A;  4EFC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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