3NZ4A

Crystal structure of a taxus phenylalanine aminomutase
Total Genus 257
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
257
sequence length
670
structure length
653
Chain Sequence
SRSHVKDILGLINTFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAEDGADIYGVTTGFGACSSRRTNQLSELQESLIRCLLAGVFTKGCASSVDELPATVTRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATALASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQDLSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTDEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFGSILALHKETDTLVDRLAEFEKRLSDRLENEMTAVRVLYEKVRIQGSRFLPFYRFVRDELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Mechanistic, mutational, and structural evaluation of a taxus phenylalanine aminomutase.
pubmed doi rcsb
molecule tags Lyase
source organism Taxus canadensis
molecule keywords Phenylalanine ammonia-lyase
total genus 257
structure length 653
sequence length 670
chains with identical sequence B
ec nomenclature ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00221 Lyase_aromatic Aromatic amino acid lyase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.274.20 Mainly Alpha Orthogonal Bundle Enzyme I; Chain A, domain 2 Phenylalanine ammonia-lyase 1; domain 3 3nz4A03
1.10.275.10 Mainly Alpha Orthogonal Bundle Fumarase C; Chain B, domain 1 Fumarase/aspartase (N-terminal domain) 3nz4A01
1.20.200.10 Mainly Alpha Up-down Bundle Fumarase C; Chain A, domain 2 Fumarase/aspartase (Central domain) 3nz4A02
2O6YA 2NYNA 2RJRA 2RJSA 1AUWA 1K62A 4C5RA 1VDKA 1J3UA 1TJWA 2QGAB 2O7EA 5HW2A 1GKJA 1U15A 1JSWA 1Q5NA 1GK3A 2YIIA 1YISA 1W27A 3RRPA 5EYVA 1FUQA 2O7BA 1B8FA 2X75A 1U16A 1HY1A 1FUOA 4FLCA 2QVEA 3QBPA 4CQ5A 2PTRA 1RE5A 4EFCA 1K7WA 2O78A 2FUSA 3NZ4A 2NYFA 4NLEA 4V2QA 1DOFA 1YFEA 4C6GA 4BAAA 1C3CA 2J91A 5D6BA 4APAA 2O7FA 4C5UA 1GK2A 4APBA 1T6JA 1FURA 4FFXA 3GTDA 3NO9A 4C5SA 3GZHA 1GKMA 3E04A 1HY0A 3CZOA 3RD8A 5EYTA 3R6VA 3R6YA 1TJUA 3R6QA 2HVGA 3KDZA 1Y2MA 3OCFA 1YFMA 5F92A 1EB4A 2PTQA 3OCEA 2VD6A 3UNVA 4BABA 2O7DA 4ADLA 1I0AA 1XWOA 1DCNA 2PTSA 4ADMA 2E9FA 1TJVA 1T6PA 4V2RA 1FUPA 4NSLA 3C8TA 2PFMA 1C3UA 4HGVA 4MX2A 3BHGA 1TJ7A 2OHYA 5F91A 1KQ7A 3TV2A 3KDYA 4EEIA
chains in the Genus database with same CATH superfamily
3GTJA 2VSFA 2HWGA 4FBSA 2O6YA 2NYNA 2RJRA 2RJSA 2FELA 1AUWA 1K62A 1TWGA 4C5RA 1VDKA 1J3UA 2N3EA 1TJWA 2QGAB 1EZBA 4CEJA 2O7EA 2JA5A 1YNND 5HW2A 5IZ2A 1GKJA 1U15A 1JSWA 1Q5NA 1GK3A 2YIIA 1YISA 1W27A 1ZYMA 3RRPA 2LPJA 1SFOA 5EYVA 3EZBA 1FUQA 2X0OA 2O7BA 1EZAA 3H0GA 1B8FA 2X75A 1U16A 4WNLA 1I3QA 1HY1A 2MX9A 1TWFA 2JA7A 2E2IA 1FUOA 2QVEA 1Y1WA 4FLCA 3QBPA 4CQ5A 2NVYA 2PTRA 1WCMA 3CRW1 1RE5A 5M0IA 2X0PA 2X0QA 4EFCA 1IW7D 1K7WA 2EZBA 1XMDA 4C2MA 2JA6A 2O78A 2YU9A 4A15A 3CQZA 2K3OA 2K3QA 1TWAA 3GTQA 2HROA 3U4QA 3LR8A 2LKMB 3GTMA 2R93A 2FUSA 2Y0NA 3LR6A 3NZ4A 2NYFA 4NLEA 2A6HD 4V2QA 1DOFA 3GTPA 1YFEA 1SMYD 1R9TA 2VL7A 1YNJD 2R92A 4C6GA 4BAAA 3FKIA 1Y1VA 1XL7A 2B63A 3CRVA 1C3CA 2J91A 5D6BA 1ZYRD 2CW0D 4APAA 2O7FA 4C5UA 2F5JA 1GK2A 4APBA 4CEHA 3U44A 2O5JD 1T6JA 1FURA 4FFXA 1XMCA 3GTDA 3GTGA 2R7ZA 3NO9A 4C5SA 2MX8A 3GZHA 2VK9A 1GKMA 3E04A 2LTHA 1TWCA 1HY0A 3CZOA 2A68D 3RD8A 2AQLA 2MQAA 5EYTA 3GTOA 3R6YA 1I6VD 3R6VA 2FENA 1HQMD 1K83A 1XL8A 2K3NA 3GTKA 1TJUA 3R6QA 2HVGA 3KDZA 1Y2MA 2EZCA 3OCFA 2FIOA 1YFMA 5F92A 1EB4A 3EZAA 2MP0A 3LRDA 1XLYA 1TWHA 2PTQA 1I50A 3OCEA 4QIWA 2VD6A 2A6ED 3UNVA 4BABA 2O7DA 4ADLA 1I0AA 2EZAA 1XWOA 2NVXA 1DCNA 2PTSA 2E2HA 4ADMA 2A69D 2E9FA 1TJVA 1T6PA 2N1DB 4V2RA 1FUPA 4NSLA 5H8WA 3C8TA 2PFMA 1C3UA 4HGVA 4MX2A 3BHGA 1TJ7A 2OHYA 2LPIA 3LR2A 4CEIA 5F91A 5M0JA 1KQ7A 3GTLA 2FIPA 3TV2A 2LYIA 2VUMA 3KDYA 3EZEA 2BE5D 4EEIA
chains in the Genus database with same CATH topology
2O6YA 2NYNA 2RJRA 2RJSA 1AUWA 1K62A 4C5RA 1VDKA 1J3UA 1TJWA 2QGAB 2O7EA 5HW2A 1GKJA 1U15A 1JSWA 1Q5NA 1GK3A 2YIIA 1YISA 1W27A 3RRPA 5EYVA 1FUQA 2O7BA 1B8FA 2X75A 1U16A 1HY1A 1FUOA 4FLCA 2QVEA 3QBPA 4CQ5A 2PTRA 1RE5A 4EFCA 1K7WA 2O78A 2FUSA 3NZ4A 2NYFA 4NLEA 4V2QA 1DOFA 1YFEA 4C6GA 4BAAA 1C3CA 2J91A 5D6BA 4APAA 2O7FA 4C5UA 1GK2A 4APBA 1T6JA 1FURA 4FFXA 3GTDA 3NO9A 4C5SA 3GZHA 1GKMA 3E04A 1HY0A 3CZOA 3RD8A 5EYTA 3R6VA 3R6YA 1TJUA 3R6QA 2HVGA 3KDZA 1Y2MA 3OCFA 1YFMA 5F92A 1EB4A 2PTQA 3OCEA 2VD6A 3UNVA 4BABA 2O7DA 4ADLA 1I0AA 1XWOA 1DCNA 2PTSA 4ADMA 2E9FA 1TJVA 1T6PA 4V2RA 1FUPA 4NSLA 3C8TA 2PFMA 1C3UA 4HGVA 4MX2A 3BHGA 1TJ7A 2OHYA 5F91A 1KQ7A 3TV2A 3KDYA 4EEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2O6Y A;  2NYN A;  2RJR A;  2RJS A;  1AUW A;  1K62 A;  4C5R A;  1VDK A;  1J3U A;  1TJW A;  2QGA B;  2O7E A;  5HW2 A;  1GKJ A;  1U15 A;  1JSW A;  1Q5N A;  1GK3 A;  2YII A;  1YIS A;  1W27 A;  3RRP A;  5EYV A;  1FUQ A;  2O7B A;  1B8F A;  2X75 A;  1U16 A;  1HY1 A;  1FUO A;  4FLC A;  2QVE A;  3QBP A;  4CQ5 A;  2PTR A;  1RE5 A;  4EFC A;  1K7W A;  2O78 A;  2FUS A;  3NZ4 A;  2NYF A;  4NLE A;  4V2Q A;  1DOF A;  1YFE A;  4C6G A;  4BAA A;  1C3C A;  2J91 A;  5D6B A;  4APA A;  2O7F A;  4C5U A;  1GK2 A;  4APB A;  1T6J A;  1FUR A;  4FFX A;  3GTD A;  3NO9 A;  4C5S A;  3GZH A;  1GKM A;  3E04 A;  1HY0 A;  3CZO A;  3RD8 A;  5EYT A;  3R6V A;  3R6Y A;  1TJU A;  3R6Q A;  2HVG A;  3KDZ A;  1Y2M A;  3OCF A;  1YFM A;  5F92 A;  1EB4 A;  2PTQ A;  3OCE A;  2VD6 A;  3UNV A;  4BAB A;  2O7D A;  4ADL A;  1I0A A;  1XWO A;  1DCN A;  2PTS A;  4ADM A;  2E9F A;  1TJV A;  1T6P A;  4V2R A;  1FUP A;  4NSL A;  3C8T A;  2PFM A;  1C3U A;  4HGV A;  4MX2 A;  3BHG A;  1TJ7 A;  2OHY A;  5F91 A;  1KQ7 A;  3TV2 A;  3KDY A;  4EEI A; 
#chains in the Genus database with same CATH topology
 3GTJ A;  2VSF A;  2HWG A;  4FBS A;  2O6Y A;  2NYN A;  2RJR A;  2RJS A;  2FEL A;  1AUW A;  1K62 A;  1TWG A;  4C5R A;  1VDK A;  1J3U A;  2N3E A;  1TJW A;  2QGA B;  1EZB A;  4CEJ A;  2O7E A;  2JA5 A;  1YNN D;  5HW2 A;  5IZ2 A;  1GKJ A;  1U15 A;  1JSW A;  1Q5N A;  1GK3 A;  2YII A;  1YIS A;  1W27 A;  1ZYM A;  3RRP A;  2LPJ A;  1SFO A;  5EYV A;  3EZB A;  1FUQ A;  2X0O A;  2O7B A;  1EZA A;  3H0G A;  1B8F A;  2X75 A;  1U16 A;  4WNL A;  1I3Q A;  1HY1 A;  2MX9 A;  1TWF A;  2JA7 A;  2E2I A;  1FUO A;  2QVE A;  1Y1W A;  4FLC A;  3QBP A;  4CQ5 A;  2NVY A;  2PTR A;  1WCM A;  3CRW 1;  1RE5 A;  5M0I A;  2X0P A;  2X0Q A;  4EFC A;  1IW7 D;  1K7W A;  2EZB A;  1XMD A;  4C2M A;  2JA6 A;  2O78 A;  2YU9 A;  4A15 A;  3CQZ A;  2K3O A;  2K3Q A;  1TWA A;  3GTQ A;  2HRO A;  3U4Q A;  3LR8 A;  2LKM B;  3GTM A;  2R93 A;  2FUS A;  2Y0N A;  3LR6 A;  3NZ4 A;  2NYF A;  4NLE A;  2A6H D;  4V2Q A;  1DOF A;  3GTP A;  1YFE A;  1SMY D;  1R9T A;  2VL7 A;  1YNJ D;  2R92 A;  4C6G A;  4BAA A;  3FKI A;  1Y1V A;  1XL7 A;  2B63 A;  3CRV A;  1C3C A;  2J91 A;  5D6B A;  1ZYR D;  2CW0 D;  4APA A;  2O7F A;  4C5U A;  2F5J A;  1GK2 A;  4APB A;  4CEH A;  3U44 A;  2O5J D;  1T6J A;  1FUR A;  4FFX A;  1XMC A;  3GTD A;  3GTG A;  2R7Z A;  3NO9 A;  4C5S A;  2MX8 A;  3GZH A;  2VK9 A;  1GKM A;  3E04 A;  2LTH A;  1TWC A;  1HY0 A;  3CZO A;  2A68 D;  3RD8 A;  2AQL A;  2MQA A;  5EYT A;  3GTO A;  3R6Y A;  1I6V D;  3R6V A;  2FEN A;  1HQM D;  1K83 A;  1XL8 A;  2K3N A;  3GTK A;  1TJU A;  3R6Q A;  2HVG A;  3KDZ A;  1Y2M A;  2EZC A;  3OCF A;  2FIO A;  1YFM A;  5F92 A;  1EB4 A;  3EZA A;  2MP0 A;  3LRD A;  1XLY A;  1TWH A;  2PTQ A;  1I50 A;  3OCE A;  4QIW A;  2VD6 A;  2A6E D;  3UNV A;  4BAB A;  2O7D A;  4ADL A;  1I0A A;  2EZA A;  1XWO A;  2NVX A;  1DCN A;  2PTS A;  2E2H A;  4ADM A;  2A69 D;  2E9F A;  1TJV A;  1T6P A;  2N1D B;  4V2R A;  1FUP A;  4NSL A;  5H8W A;  3C8T A;  2PFM A;  1C3U A;  4HGV A;  4MX2 A;  3BHG A;  1TJ7 A;  2OHY A;  2LPI A;  3LR2 A;  4CEI A;  5F91 A;  5M0J A;  1KQ7 A;  3GTL A;  2FIP A;  3TV2 A;  2LYI A;  2VUM A;  3KDY A;  3EZE A;  2BE5 D;  4EEI A; 
#chains in the Genus database with same CATH homology
 2O6Y A;  2NYN A;  2RJR A;  2RJS A;  1AUW A;  1K62 A;  4C5R A;  1VDK A;  1J3U A;  1TJW A;  2QGA B;  2O7E A;  5HW2 A;  1GKJ A;  1U15 A;  1JSW A;  1Q5N A;  1GK3 A;  2YII A;  1YIS A;  1W27 A;  3RRP A;  5EYV A;  1FUQ A;  2O7B A;  1B8F A;  2X75 A;  1U16 A;  1HY1 A;  1FUO A;  4FLC A;  2QVE A;  3QBP A;  4CQ5 A;  2PTR A;  1RE5 A;  4EFC A;  1K7W A;  2O78 A;  2FUS A;  3NZ4 A;  2NYF A;  4NLE A;  4V2Q A;  1DOF A;  1YFE A;  4C6G A;  4BAA A;  1C3C A;  2J91 A;  5D6B A;  4APA A;  2O7F A;  4C5U A;  1GK2 A;  4APB A;  1T6J A;  1FUR A;  4FFX A;  3GTD A;  3NO9 A;  4C5S A;  3GZH A;  1GKM A;  3E04 A;  1HY0 A;  3CZO A;  3RD8 A;  5EYT A;  3R6V A;  3R6Y A;  1TJU A;  3R6Q A;  2HVG A;  3KDZ A;  1Y2M A;  3OCF A;  1YFM A;  5F92 A;  1EB4 A;  2PTQ A;  3OCE A;  2VD6 A;  3UNV A;  4BAB A;  2O7D A;  4ADL A;  1I0A A;  1XWO A;  1DCN A;  2PTS A;  4ADM A;  2E9F A;  1TJV A;  1T6P A;  4V2R A;  1FUP A;  4NSL A;  3C8T A;  2PFM A;  1C3U A;  4HGV A;  4MX2 A;  3BHG A;  1TJ7 A;  2OHY A;  5F91 A;  1KQ7 A;  3TV2 A;  3KDY A;  4EEI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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