4BAA | Genus

Total Genus 245

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	245
sequence length	667
structure length	635
Chain Sequence	SHVKDILGLINAFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAEDGADIYGVTTGFGACSSSRTNRLSELQESLIRCLLAGVFTDELPATATRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATAVASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQELSREYYSIDKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTEEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFDTILALHTLVDRLAEFEKRLSDRLENEMTAVRVLYERIQGSKFLPFYRFVREELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFL

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lyase
source organism	Taxus wallichiana var. chinensis
publication title	Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase rcsb
molecule keywords	PHENYLALANINE AMMONIA-LYASE
total genus	245
structure length	635
sequence length	667
chains with identical sequence	B, C, D
ec nomenclature	ec 4.3.1.24: Phenylalanine ammonia-lyase.
pdb deposition date	2012-09-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00221	Lyase_aromatic	Aromatic amino acid lyase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.274.20	Mainly Alpha	Orthogonal Bundle	Enzyme I; Chain A, domain 2	Phenylalanine ammonia-lyase 1; domain 3	4baaA03
1.10.275.10	Mainly Alpha	Orthogonal Bundle	Fumarase C; Chain B, domain 1	Fumarase/aspartase (N-terminal domain)	4baaA01
1.20.200.10	Mainly Alpha	Up-down Bundle	Fumarase C; Chain A, domain 2	Fumarase/aspartase (Central domain)	4baaA02

5HW2A 1TJVA 1J3UA 2O7DA 1XWOA 5EYVA 2QGAB 3RD8A 2O7EA 1K7WA 4FFXA 2FUSA 1DOFA 4C5RA 1W27A 1T6PA 1JSWA 5D6BA 3NZ4A 2O7FA 3BHGA 2NYNA 2OHYA 3UNVA 1I0AA 4APBA 4NLEA 3TV2A 2YIIA 3GTDA 4C5UA 1VDKA 1TJUA 3R6VA 4V2QA 3OCFA 3KDZA 3GZHA 1YISA 5F92A 1C3CA 4EEIA 1U16A 1FURA 2NYFA 2PFMA 1EB4A 2PTRA 1FUOA 2HVGA 3QBPA 1Y2MA 1DCNA 2O7BA 1GKMA 1TJ7A 1FUPA 1AUWA 2PTSA 3RRPA 4APAA 1K62A 1FUQA 2X75A 1HY0A 1C3UA 2RJRA 2VD6A 4MX2A 3E04A 1GK2A 4FLCA 1TJWA 3NO9A 4ADLA 1B8FA 2RJSA 4EFCA 1YFMA 1KQ7A 4V2RA 5EYTA 4HGVA 1T6JA 3C8TA 4NSLA 5F91A 1GKJA 4CQ5A 2QVEA 1HY1A 3R6YA 2E9FA 4ADMA 1YFEA 2O78A 3KDYA 3CZOA 3R6QA 2J91A 1Q5NA 1GK3A 1RE5A 1U15A 4C6GA 3OCEA 4BABA 4C5SA 4BAAA 2PTQA 2O6YA
chains in the Genus database with same CATH superfamily

1TWHA 1TWAA 3GTLA 2AQLA 5HW2A 3GTGA 1TJVA 2CW0D 2E2IA 1J3UA 2O7DA 1XWOA 5EYVA 2HWGA 2QGAB 2JA5A 1SFOA 2LPIA 1EZBA 3RD8A 2O7EA 1K7WA 4FFXA 4CEHA 2FUSA 1DOFA 2N1DB 2EZBA 2N3EA 4C5RA 1W27A 2F5JA 2VUMA 1YNJD 1T6PA 1XL8A 1YNND 4A15A 1Y1WA 2Y0NA 1JSWA 1EZAA 2A69D 3GTKA 1ZYRD 2X0PA 3FKIA 1XLYA 5D6BA 3NZ4A 2BE5D 2O7FA 2NYNA 2OHYA 3BHGA 1I0AA 4NLEA 3UNVA 4APBA 3TV2A 2O5JD 1I6VD 2YIIA 3GTDA 4C5UA 3GTPA 1VDKA 1TJUA 1TWCA 3R6VA 2K3OA 1TWGA 4V2QA 3OCFA 2X0QA 3H0GA 3KDZA 3GZHA 2FENA 1YISA 2EZAA 5F92A 1C3CA 4EEIA 1U16A 1Y1VA 1FURA 2NYFA 2VSFA 5IZ2A 2A6ED 2FIOA 2JA7A 1EB4A 2PFMA 2PTRA 1FUOA 2HVGA 3QBPA 1Y2MA 1ZYMA 1DCNA 5M0JA 1TWFA 2E2HA 2O7BA 2A6HD 3LR8A 2MX9A 3U44A 2B63A 1GKMA 1TJ7A 1FUPA 2LPJA 1AUWA 2NVYA 2PTSA 3RRPA 4APAA 3EZEA 1WCMA 2JA6A 1FUQA 1K62A 1XMCA 4CEIA 2X75A 1HY0A 1C3UA 2RJRA 2VD6A 4MX2A 2K3QA 3E04A 1GK2A 4FLCA 3GTQA 2R93A 1TJWA 2MQAA 4C2MA 3NO9A 4ADLA 3LR6A 1B8FA 2X0OA 2RJSA 4EFCA 3LRDA 1KQ7A 1YFMA 4V2RA 3LR2A 5EYTA 4HGVA 2YU9A 4CEJA 2A68D 1T6JA 3GTOA 1XMDA 3C8TA 4NSLA 4FBSA 3GTMA 2FELA 5F91A 2VK9A 3EZAA 3GTJA 1I3QA 1GKJA 4QIWA 4CQ5A 3EZBA 2QVEA 1HY1A 1R9TA 1SMYD 3R6YA 2E9FA 3CQZA 2MX8A 4ADMA 1YFEA 2O78A 3KDYA 1K83A 3CRVA 2EZCA 2HROA 2LKMB 5M0IA 2LYIA 1I50A 1IW7D 5H8WA 2NVXA 3CZOA 2R92A 3R6QA 2J91A 1Q5NA 3CRW1 1GK3A 1RE5A 4WNLA 1U15A 2MP0A 4C6GA 3OCEA 4BABA 1HQMD 1XL7A 4C5SA 2LTHA 4BAAA 2VL7A 2PTQA 2FIPA 2R7ZA 3U4QA 2O6YA 2K3NA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5HW2 A;  1TJV A;  1J3U A;  2O7D A;  1XWO A;  5EYV A;  2QGA B;  3RD8 A;  2O7E A;  1K7W A;  4FFX A;  2FUS A;  1DOF A;  4C5R A;  1W27 A;  1T6P A;  1JSW A;  5D6B A;  3NZ4 A;  2O7F A;  3BHG A;  2NYN A;  2OHY A;  3UNV A;  1I0A A;  4APB A;  4NLE A;  3TV2 A;  2YII A;  3GTD A;  4C5U A;  1VDK A;  1TJU A;  3R6V A;  4V2Q A;  3OCF A;  3KDZ A;  3GZH A;  1YIS A;  5F92 A;  1C3C A;  4EEI A;  1U16 A;  1FUR A;  2NYF A;  2PFM A;  1EB4 A;  2PTR A;  1FUO A;  2HVG A;  3QBP A;  1Y2M A;  1DCN A;  2O7B A;  1GKM A;  1TJ7 A;  1FUP A;  1AUW A;  2PTS A;  3RRP A;  4APA A;  1K62 A;  1FUQ A;  2X75 A;  1HY0 A;  1C3U A;  2RJR A;  2VD6 A;  4MX2 A;  3E04 A;  1GK2 A;  4FLC A;  1TJW A;  3NO9 A;  4ADL A;  1B8F A;  2RJS A;  4EFC A;  1YFM A;  1KQ7 A;  4V2R A;  5EYT A;  4HGV A;  1T6J A;  3C8T A;  4NSL A;  5F91 A;  1GKJ A;  4CQ5 A;  2QVE A;  1HY1 A;  3R6Y A;  2E9F A;  4ADM A;  1YFE A;  2O78 A;  3KDY A;  3CZO A;  3R6Q A;  2J91 A;  1Q5N A;  1GK3 A;  1RE5 A;  1U15 A;  4C6G A;  3OCE A;  4BAB A;  4C5S A;  4BAA A;  2PTQ A;  2O6Y A; 
#chains in the Genus database with same CATH topology
 1TWH A;  1TWA A;  3GTL A;  2AQL A;  5HW2 A;  3GTG A;  1TJV A;  2CW0 D;  2E2I A;  1J3U A;  2O7D A;  1XWO A;  5EYV A;  2HWG A;  2QGA B;  2JA5 A;  1SFO A;  2LPI A;  1EZB A;  3RD8 A;  2O7E A;  1K7W A;  4FFX A;  4CEH A;  2FUS A;  1DOF A;  2N1D B;  2EZB A;  2N3E A;  4C5R A;  1W27 A;  2F5J A;  2VUM A;  1YNJ D;  1T6P A;  1XL8 A;  1YNN D;  4A15 A;  1Y1W A;  2Y0N A;  1JSW A;  1EZA A;  2A69 D;  3GTK A;  1ZYR D;  2X0P A;  3FKI A;  1XLY A;  5D6B A;  3NZ4 A;  2BE5 D;  2O7F A;  2NYN A;  2OHY A;  3BHG A;  1I0A A;  4NLE A;  3UNV A;  4APB A;  3TV2 A;  2O5J D;  1I6V D;  2YII A;  3GTD A;  4C5U A;  3GTP A;  1VDK A;  1TJU A;  1TWC A;  3R6V A;  2K3O A;  1TWG A;  4V2Q A;  3OCF A;  2X0Q A;  3H0G A;  3KDZ A;  3GZH A;  2FEN A;  1YIS A;  2EZA A;  5F92 A;  1C3C A;  4EEI A;  1U16 A;  1Y1V A;  1FUR A;  2NYF A;  2VSF A;  5IZ2 A;  2A6E D;  2FIO A;  2JA7 A;  1EB4 A;  2PFM A;  2PTR A;  1FUO A;  2HVG A;  3QBP A;  1Y2M A;  1ZYM A;  1DCN A;  5M0J A;  1TWF A;  2E2H A;  2O7B A;  2A6H D;  3LR8 A;  2MX9 A;  3U44 A;  2B63 A;  1GKM A;  1TJ7 A;  1FUP A;  2LPJ A;  1AUW A;  2NVY A;  2PTS A;  3RRP A;  4APA A;  3EZE A;  1WCM A;  2JA6 A;  1FUQ A;  1K62 A;  1XMC A;  4CEI A;  2X75 A;  1HY0 A;  1C3U A;  2RJR A;  2VD6 A;  4MX2 A;  2K3Q A;  3E04 A;  1GK2 A;  4FLC A;  3GTQ A;  2R93 A;  1TJW A;  2MQA A;  4C2M A;  3NO9 A;  4ADL A;  3LR6 A;  1B8F A;  2X0O A;  2RJS A;  4EFC A;  3LRD A;  1KQ7 A;  1YFM A;  4V2R A;  3LR2 A;  5EYT A;  4HGV A;  2YU9 A;  4CEJ A;  2A68 D;  1T6J A;  3GTO A;  1XMD A;  3C8T A;  4NSL A;  4FBS A;  3GTM A;  2FEL A;  5F91 A;  2VK9 A;  3EZA A;  3GTJ A;  1I3Q A;  1GKJ A;  4QIW A;  4CQ5 A;  3EZB A;  2QVE A;  1HY1 A;  1R9T A;  1SMY D;  3R6Y A;  2E9F A;  3CQZ A;  2MX8 A;  4ADM A;  1YFE A;  2O78 A;  3KDY A;  1K83 A;  3CRV A;  2EZC A;  2HRO A;  2LKM B;  5M0I A;  2LYI A;  1I50 A;  1IW7 D;  5H8W A;  2NVX A;  3CZO A;  2R92 A;  3R6Q A;  2J91 A;  1Q5N A;  3CRW 1;  1GK3 A;  1RE5 A;  4WNL A;  1U15 A;  2MP0 A;  4C6G A;  3OCE A;  4BAB A;  1HQM D;  1XL7 A;  4C5S A;  2LTH A;  4BAA A;  2VL7 A;  2PTQ A;  2FIP A;  2R7Z A;  3U4Q A;  2O6Y A;  2K3N A; 
#chains in the Genus database with same CATH homology
 5HW2 A;  1TJV A;  1J3U A;  2O7D A;  1XWO A;  5EYV A;  2QGA B;  3RD8 A;  2O7E A;  1K7W A;  4FFX A;  2FUS A;  1DOF A;  4C5R A;  1W27 A;  1T6P A;  1JSW A;  5D6B A;  3NZ4 A;  2O7F A;  3BHG A;  2NYN A;  2OHY A;  3UNV A;  1I0A A;  4APB A;  4NLE A;  3TV2 A;  2YII A;  3GTD A;  4C5U A;  1VDK A;  1TJU A;  3R6V A;  4V2Q A;  3OCF A;  3KDZ A;  3GZH A;  1YIS A;  5F92 A;  1C3C A;  4EEI A;  1U16 A;  1FUR A;  2NYF A;  2PFM A;  1EB4 A;  2PTR A;  1FUO A;  2HVG A;  3QBP A;  1Y2M A;  1DCN A;  2O7B A;  1GKM A;  1TJ7 A;  1FUP A;  1AUW A;  2PTS A;  3RRP A;  4APA A;  1K62 A;  1FUQ A;  2X75 A;  1HY0 A;  1C3U A;  2RJR A;  2VD6 A;  4MX2 A;  3E04 A;  1GK2 A;  4FLC A;  1TJW A;  3NO9 A;  4ADL A;  1B8F A;  2RJS A;  4EFC A;  1YFM A;  1KQ7 A;  4V2R A;  5EYT A;  4HGV A;  1T6J A;  3C8T A;  4NSL A;  5F91 A;  1GKJ A;  4CQ5 A;  2QVE A;  1HY1 A;  3R6Y A;  2E9F A;  4ADM A;  1YFE A;  2O78 A;  3KDY A;  3CZO A;  3R6Q A;  2J91 A;  1Q5N A;  1GK3 A;  1RE5 A;  1U15 A;  4C6G A;  3OCE A;  4BAB A;  4C5S A;  4BAA A;  2PTQ A;  2O6Y A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4BAAA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations