The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
230
|
sequence length |
667
|
structure length |
611
|
Chain Sequence |
SHVKDILGLINAFNEVKKITVDGTTPITVAHVAALARRHDVKVALEAEQCRARVETCSSWVQRKAESELQESLIRCLLAGVFTDELPATATRSAMLLRLNSFTYGCSGIRWEVMEALEKLLNSNVSPKVPLRGSVSDLIPLAYIAGLLIGKPSVIARIGDDVEVPAPEALSRVGLRPFKLQAKEGLALVNGTSFATAVASTVMYDANVLLLLVETLCGMFCEVIFGREEFAHPLIHKVKPHPGQIESAELLEWLLRSSPFQELSREYYSIDKLKKPKQDRYALRSSPQWLAPLVQTIRDATTTVETEVNSANDNPIIDHANDRALHGANFQGSAVGFYMDYVRIAVAGLGKLLFAQFTELMIEYYSNGLPGNLSLGPDLSVDYGLKGLDIAMAAYSSELQYLANPVTTHVHSAEQHNQDINSLALISARKTEEALDILKLMIASHLTAMCQAVDLRQLEEALVKVVENVVSTLADECGLPNDTKARLLYVAKAVPVYTYLESPCDPTLPLLLGLKQSCFDTILALHDTLVDRLAEFRLENEMTAVRVLYEKVRIQGSKFLPFYRFVREELDTGVMSARREQTPQEDVQKVFDAIADGRITVPLLHCLQGFL
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase
rcsb |
| molecule tags |
Lyase
|
| source organism |
Taxus wallichiana var. chinensis
|
| molecule keywords |
PHENYLALANINE AMINOMUTASE
|
| total genus |
230
|
| structure length |
611
|
| sequence length |
667
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature |
ec
4.3.1.24: Phenylalanine ammonia-lyase. |
| pdb deposition date | 2012-09-12 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00221 | Lyase_aromatic | Aromatic amino acid lyase |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Orthogonal Bundle | Enzyme I; Chain A, domain 2 | Phenylalanine ammonia-lyase 1; domain 3 | ||
| Mainly Alpha | Orthogonal Bundle | Fumarase C; Chain B, domain 1 | Fumarase/aspartase (N-terminal domain) | ||
| Mainly Alpha | Up-down Bundle | Fumarase C; Chain A, domain 2 | Fumarase/aspartase (Central domain) |
#chains in the Genus database with same CATH superfamily 1W27 A; 4NSL A; 1J3U A; 3TV2 A; 2X75 A; 4FFX A; 3NZ4 A; 1TJ7 A; 3E04 A; 4C5S A; 3GTD A; 1K62 A; 4APB A; 2PFM A; 1DCN A; 3C8T A; 2RJR A; 2O7F A; 1FUQ A; 3R6V A; 4C5U A; 1TJV A; 2O7D A; 1RE5 A; 1I0A A; 3OCE A; 1Y2M A; 1GKJ A; 2FUS A; 5EYT A; 2O78 A; 2RJS A; 1TJW A; 2VD6 A; 5F91 A; 4ADM A; 4C6G A; 4V2R A; 1JSW A; 1FUP A; 1U16 A; 2OHY A; 2NYF A; 1XWO A; 2HVG A; 4FLC A; 2O7E A; 1K7W A; 4CQ5 A; 3RD8 A; 5F92 A; 4APA A; 4EFC A; 4EEI A; 1FUO A; 2PTQ A; 1YFM A; 4BAB A; 1B8F A; 1GK2 A; 1HY0 A; 4C5R A; 2PTR A; 1T6P A; 1TJU A; 4NLE A; 5D6B A; 4ADL A; 1AUW A; 1GK3 A; 3CZO A; 3QBP A; 3UNV A; 3R6Y A; 4BAA A; 1FUR A; 1VDK A; 3RRP A; 3BHG A; 1DOF A; 2QGA B; 1C3C A; 1Q5N A; 2QVE A; 2O6Y A; 1EB4 A; 1YFE A; 2E9F A; 1T6J A; 2NYN A; 3R6Q A; 1HY1 A; 3GZH A; 4MX2 A; 1GKM A; 3NO9 A; 3OCF A; 4V2Q A; 2J91 A; 1U15 A; 5EYV A; 5HW2 A; 1C3U A; 3KDZ A; 2PTS A; 2O7B A; 1KQ7 A; 3KDY A; 4HGV A; 1YIS A; 2YII A; #chains in the Genus database with same CATH topology 3GTJ A; 1W27 A; 4NSL A; 1J3U A; 3TV2 A; 2X75 A; 4FFX A; 2A68 D; 1EZA A; 2K3N A; 1YNN D; 3U4Q A; 1Y1W A; 3NZ4 A; 1TJ7 A; 4FBS A; 4C5S A; 3E04 A; 2E2I A; 1K62 A; 2FIO A; 3GTD A; 4CEH A; 2R93 A; 4APB A; 2PFM A; 2B63 A; 1DCN A; 1TWC A; 2MX8 A; 2VK9 A; 3C8T A; 2RJR A; 2F5J A; 2O7F A; 1FUQ A; 3R6V A; 3CQZ A; 4C5U A; 1TJV A; 4A15 A; 2AQL A; 4WNL A; 2O7D A; 1RE5 A; 1I0A A; 1XL8 A; 2VUM A; 3OCE A; 1XMD A; 1Y2M A; 1GKJ A; 2FUS A; 5IZ2 A; 2VSF A; 5EYT A; 5H8W A; 1SFO A; 2O78 A; 1K83 A; 3CRW 1; 3H0G A; 1XL7 A; 1I3Q A; 2RJS A; 5M0J A; 1TWF A; 1TJW A; 2VD6 A; 5F91 A; 4ADM A; 2LPJ A; 4C6G A; 4V2R A; 3GTO A; 1JSW A; 1TWH A; 3U44 A; 1TWG A; 3LR6 A; 1HQM D; 1U16 A; 2OHY A; 2NYF A; 5M0I A; 1XWO A; 3LR8 A; 2X0P A; 2HVG A; 4FLC A; 2O7E A; 3EZB A; 3LR2 A; 1K7W A; 4CQ5 A; 3GTQ A; 4QIW A; 2R7Z A; 1YIS A; 3RD8 A; 5F92 A; 3EZA A; 3GTG A; 4APA A; 2EZB A; 2LKM B; 2N3E A; 4EFC A; 4EEI A; 2A6E D; 1FUO A; 2PTQ A; 3GTM A; 1YFM A; 4BAB A; 2O5J D; 1B8F A; 1I6V D; 2MP0 A; 1GK2 A; 1HY0 A; 4C5R A; 1XLY A; 2PTR A; 1T6P A; 2JA5 A; 1ZYR D; 4C2M A; 2JA6 A; 1TJU A; 2LYI A; 2E2H A; 2LTH A; 4NLE A; 5D6B A; 2YU9 A; 4ADL A; 2FEN A; 1AUW A; 2VL7 A; 1GK3 A; 3CZO A; 3QBP A; 3UNV A; 3R6Y A; 2LPI A; 4BAA A; 1FUR A; 2K3O A; 1R9T A; 1VDK A; 3RRP A; 2BE5 D; 1ZYM A; 3GTL A; 2EZC A; 3BHG A; 1DOF A; 2QGA B; 1I50 A; 2R92 A; 3LRD A; 2A69 D; 1C3C A; 2FIP A; 1Q5N A; 2QVE A; 2O6Y A; 1WCM A; 1EB4 A; 3EZE A; 2K3Q A; 2FEL A; 1YFE A; 2E9F A; 1T6J A; 2NYN A; 3R6Q A; 1HY1 A; 2HRO A; 1TWA A; 2NVX A; 2N1D B; 3GZH A; 2A6H D; 3GTK A; 2X0O A; 3GTP A; 1EZB A; 2HWG A; 4MX2 A; 1SMY D; 2X0Q A; 1YNJ D; 1Y1V A; 1GKM A; 3NO9 A; 3OCF A; 2MQA A; 3FKI A; 4V2Q A; 2Y0N A; 2J91 A; 1U15 A; 2MX9 A; 5EYV A; 5HW2 A; 4CEJ A; 4CEI A; 1C3U A; 3CRV A; 2NVY A; 2JA7 A; 2EZA A; 2CW0 D; 2O7B A; 1KQ7 A; 2PTS A; 1XMC A; 3KDY A; 3KDZ A; 4HGV A; 1IW7 D; 1FUP A; 2YII A; #chains in the Genus database with same CATH homology 1W27 A; 4NSL A; 1J3U A; 3TV2 A; 2X75 A; 4FFX A; 3NZ4 A; 1TJ7 A; 3E04 A; 4C5S A; 3GTD A; 1K62 A; 4APB A; 2PFM A; 1DCN A; 3C8T A; 2RJR A; 2O7F A; 1FUQ A; 3R6V A; 4C5U A; 1TJV A; 2O7D A; 1RE5 A; 1I0A A; 3OCE A; 1Y2M A; 1GKJ A; 2FUS A; 5EYT A; 2O78 A; 2RJS A; 1TJW A; 2VD6 A; 5F91 A; 4ADM A; 4C6G A; 4V2R A; 1JSW A; 1FUP A; 1U16 A; 2OHY A; 2NYF A; 1XWO A; 2HVG A; 4FLC A; 2O7E A; 1K7W A; 4CQ5 A; 3RD8 A; 5F92 A; 4APA A; 4EFC A; 4EEI A; 1FUO A; 2PTQ A; 1YFM A; 4BAB A; 1B8F A; 1GK2 A; 1HY0 A; 4C5R A; 2PTR A; 1T6P A; 1TJU A; 4NLE A; 5D6B A; 4ADL A; 1AUW A; 1GK3 A; 3CZO A; 3QBP A; 3UNV A; 3R6Y A; 4BAA A; 1FUR A; 1VDK A; 3RRP A; 3BHG A; 1DOF A; 2QGA B; 1C3C A; 1Q5N A; 2QVE A; 2O6Y A; 1EB4 A; 1YFE A; 2E9F A; 1T6J A; 2NYN A; 3R6Q A; 1HY1 A; 3GZH A; 4MX2 A; 1GKM A; 3NO9 A; 3OCF A; 4V2Q A; 2J91 A; 1U15 A; 5EYV A; 5HW2 A; 1C3U A; 3KDZ A; 2PTS A; 2O7B A; 1KQ7 A; 3KDY A; 4HGV A; 1YIS A; 2YII A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
