3KXUA

Crystal structure of human ferritin ftl498instc pathogenic mutant
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
156
structure length
156
Chain Sequence
SSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Metal binding protein
molecule keywords Ferritin
publication title Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation.
pubmed doi rcsb
source organism Homo sapiens
total genus 67
structure length 156
sequence length 156
ec nomenclature
pdb deposition date 2009-12-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00210 Ferritin Ferritin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1260.10 Mainly Alpha Up-down Bundle Ferritin Ferritin 3kxuA00
3BKNA 4P18A 4TO9A 4ITTA 3PVTB 4LPJA 4CVRA 2FKZA 5D8XA 4IWKA 1JI4A 3NP0X 4RC7B 2OC5A 3EGMA 2Z6MA 3HIUA 2WLAA 5J93A 4RC5B 4TOGA 3SHXA 4KVSA 1BG7A 1S2ZA 2WTLA 1VJXA 5JACA 3BVFA 4TOEA 5GU0X 3EZUA 3WVUA 3E2CA 3WVVA 4ZL5A 4CYAA 5GU2X 3H7GA 2WLUA 3PZAA 2CLUA 1RCDA 3T9JA 3UOFA 4DI0A 3ES3A 2CF7A 3BVKA 3IQ1A 1DVBA 3A9QA 2YJKA 4EVCA 5GU3X 1S3QA 3O7RA 1R03A 3UNOA 5J8SA 3PWFA 4DYZA 3WVWA 1N1QA 1RCCA 1ZS3A 4LQVA 3BT5A 5FFDA 3FSEA 4TOCA 1MFRA 1RCGA 4REUA 4RC6A 4ZTTA 5FFAA 4LQHA 3R2KA 4DE6A 3F36A 2ZA7A 3BVEA 3KA8A 4Z5SA 2V2MA 5FFBA 5E2DA 4M35A 3ISEA 4LPMA 4MY7A 5C6FA 4CY9A 4KVQA 4II4A 3E1OA 1GWGA 3FVBA 4U3GA 2FZFA 5I4JA 5GU1X 1IERA 3AJQA 1YUXA 1DPSA 3GHQA 2G4HA 3OJ5A 4TOBA 4DZ0A 1TKPA 1VLGA 2BJYA 3ERZA 1L8HA 4R42A 5HQOA 2C41A 4AM4A 3KX9A 4PGIA 3QZ3A 2V2SA 3E1NA 4Y08A 1DATA 4ZLWA 4A25A 1JYBA 1NF6A 3KXUA 2GYQA 3QB9A 4QUWA 2C2UA 4ITWA 1JGCA 2VXIA 1Z4AA 4RC8A 4ISMA 4MKUA 4E6KA 1QYBA 1AEWA 3Q4QA 3GE4A 2YW6A 1F30A 2V2JA 4ZJKA 4ZKHA 3QHCA 2HR5A 3PWQA 1RCIA 3E6RA 2Z90A 2BW1A 1L8IA 3R2HA 3SH6A 5IX6A 4RC6B 1NNQA 2CIHA 1F33A 1YUZA 3FI6A 3E1LA 1JI5A 4PG1A 2FJCA 1MOJA 1BCFA 2XGWA 4TOAA 5CZUA 5LS9A 4M32A 3ISFA 1S30A 2IB0A 1EUMA 3R2LA 3NOZX 2FFXJ 1UVHA 1YV1A 2W0OA 5FFEA 2ZA8A 1ZUJA 4II4B 5HJHA 3AJOA 3RAVA 1XZ3A 5AXSA 2YW7A 2VZBA 4IWJA 5FEJA 2JD60 2FG4A 4DASA 5JKLA 4IXKA 4EVBA 1Z6OM 2F7NA 2JD70 2V2OA 5GOUA 3QHBA 4DYXA 2Z5RA 5JKMG 2BKCA 2ZURX 3QD8A 1OTKA 2YJJA 2HTNA 1TK6A 3F38A 4DYUA 2ZG8X 1HRSA 2D5KA 3R2OA 2QQYA 3SIDA 2ZG9X 4CVTA 3AK8A 2CLBA 3PWQC 1RCEA 1Z6OA 4KVRA 3AF8X 2FHAA 4ISPA 3QVDA 3Q4RA 2PYBA 1SQ3A 5E1UA 4AM5A 2CHIA 2V2LA 4EVDA 4ZMCA 3F32A 4Z3BA 2CEIA 4LQNA 4PG0A 3PW8A 1TKOA 3BVIA 3Q4OA 3RBCA 4DYYA 3RD0A 2JD80 1H96A 1JIGA 4CMYA 3UOIA 3TA8A 4EVEA 2ZG7X 3Q4NA 3E6SA 5HJFA 2GS4A 3KA9A 4XGSA 4MJYA 3PVRA 5D8QA 2XJNA 4LQJA 5FFCA 2Z5QA 2FL0A 4AM2A 5LG2A 4XKTA 5CMRA 2BK6A 1VEIA 1BFRA 3KWOA 1NFVA 5CMQA 4LYXA 4ERUA 5J8WA 5D8RA 1QGHA 5ERJA 1JKVA 1IESA 1JTSA 2V2NA 2V2PA 5GN8A 2XKQA 5LG8A 2VXXA 1J30A 1VEQA 3BVLA 3F39A 1TJOA 2RBDA 3AJPA 3IS8A 3PVYA 1LKPA 4M33A 4OYNA 1XZ1A 3IS7A 4TODA 3PW1A 2CN6A 3NP2X 3R2SA 1RYTA 3AK9A 3KA6A 5D8YA 3PW8C 2C6RA 2V15A 5K52A 3PVTA 3R2MA 4MUDA 2IU2A 1O9IA 3SE1A 4RC7A 4ZKXA 3KA4A 4XKUA 4RC5A 5K53A 4TOFA 2CN7A 2Y3QA 3AF9X 3F33A 4CYBA 2IY4A 3WNWA 4ML5A 5D8PA 1O9RA 4LPNA 2XJMA 4LYUA 3E1PA 4M34A 5J9VA 1B71A 3R2RA 3RGDA 2Z5PA 4ZL6A 3MPSA 4CVPA 1LKMA 4CMYV 3F35A 2UX1A 4YKHA 3AF7X 1LKOA 4CVSA 2CHPA 3E1MA 3KA3A 3PVRB 1VELA 2FG8A 2X170 2QF9A 1FHAA 3A68A 1SOFA 2V2IA 2ITBA 3RE7A 3E1JA 4PGKA 4MN9A 3U90A 5GN8B 3VNXA 3O7SA 5JKLG 3F37A 3GVYA 2C2JA 2OH3A 2GYDA 5D8SA 2ZA6A 1LB3A 4ETRA 3PVYB 4TOHA 3EZ0A 5LBHA 1JKUA 4ZKWA 3F34A 4TW3A 2C2FA 2XJOA 3HL1A 4XKSA 5D8OA 1UMNA 3PW1B 3OGHA 3E1QA 1JREA 5JKMA 1NF4A 1KRQA 2V2RA 5ERKA
chains in the Genus database with same CATH superfamily
3BKNA 4P18A 4TO9A 4ITTA 3PVTB 4LPJA 4CVRA 2FKZA 5D8XA 4IWKA 1JI4A 3NP0X 4RC7B 2OC5A 4W4LB 3EGMA 2Z6MA 3HIUA 2WLAA 5J93A 4RC5B 4TOGA 3SHXA 4KVSA 1BG7A 1S2ZA 2WTLA 1VJXA 5JACA 3BVFA 4TOEA 5GU0X 3EZUA 3UFBA 3WVUA 3E2CA 3WVVA 3LKDA 4ZL5A 4CYAA 5GU2X 3H7GA 2WLUA 3VV9A 3PZAA 2CLUA 2CWLA 1RCDA 3T9JA 3UOFA 4DI0A 3ES3A 2CF7A 3BVKA 3IQ1A 1DVBA 3A9QA 2YJKA 4EVCA 5GU3X 1S3QA 3O7RA 1R03A 3UNOA 5J8SA 3PWFA 4DYZA 3WVWA 1N1QA 1RCCA 1ZS3A 4LQVA 3BT5A 5FFDA 3FSEA 4TOCA 1MFRA 3W54A 1RCGA 4REUA 4RC6A 4ZTTA 5FFAA 4LQHA 3KDQA 3R2KA 4DE6A 2V8TA 3F36A 2ZA7A 3BVEA 3KA8A 4Z5SA 2V2MA 5FFBA 5HU6D 5E2DA 4M35A 3ISEA 4LPMA 4MY7A 5C6FA 4CY9A 4KVQA 4II4A 3E1OA 1GWGA 5JDOA 3FVBA 4U3GA 2FZFA 5I4JA 5GU1X 1IERA 3AJQA 1YUXA 1DPSA 3GHQA 3JZ9A 2G4HA 4YXMA 3OJ5A 4TOBA 4DZ0A 1TKPA 1VLGA 2BJYA 3ERZA 1L8HA 4R42A 5HQOA 3GGZA 2C41A 4AM4A 3KX9A 4PGIA 3QZ3A 2V2SA 3E1NA 4Y08A 1DATA 4ZLWA 4A25A 1JYBA 1NF6A 3C23A 3KXUA 4E40A 2GYQA 3C21A 3QB9A 4QUWA 2C2UA 4ITWA 1JGCA 2VXIA 1Z4AA 4RC8A 4ISMA 4MKUA 4E6KA 1QYBA 1AEWA 3Q4QA 3GE4A 2YW6A 1F30A 2V2JA 4ZJKA 4ZKHA 3QHCA 2HR5A 3PWQA 1RCIA 3E6RA 2Z90A 2BW1A 1L8IA 3R2HA 3SH6A 5IX6A 4RC6B 1NNQA 2CIHA 1F33A 1YUZA 3FI6A 3E1LA 4X0JA 1JI5A 4PG1A 3JZAB 2FJCA 1MOJA 1BCFA 2XGWA 4TOAA 5CZUA 5LS9A 4M32A 3ISFA 1S30A 2IB0A 2N02A 1EUMA 3R2LA 3VVAA 3NOZX 3FRSA 2FFXJ 1UVHA 1YV1A 2W0OA 5FFEA 2ZA8A 1ZUJA 3M6JA 4II4B 3AJOA 5HJHA 1XZ3A 5AXSA 3RAVA 2YW7A 2VZBA 4IWJA 5FEJA 2JD60 3GGYA 2FG4A 4DASA 5JKLA 4IXKA 4EVBA 5JDOB 1Z6OM 2F7NA 2JD70 2V2OA 5GOUA 3QHBA 4DYXA 2Z5RA 5JKMG 2BKCA 2ZURX 2OKCA 3QD8A 1OTKA 2YJJA 2HTNA 1TK6A 3F38A 4DYUA 2ZG8X 1HRSA 2D5KA 3R2OA 2QQYA 3SIDA 3C1ZA 2ZG9X 4CVTA 3AK8A 4WJG4 2CLBA 2Y44A 3PWQC 1RCEA 1Z6OA 4KVRA 3AF8X 2FHAA 4ISPA 3V3KB 3QVDA 3Q4RA 4W4KB 2PYBA 1SQ3A 5E1UA 4AM5A 2CHIA 2V2LA 4EVDA 4ZMCA 3F32A 4Z3BA 2CEIA 4LQNA 4PG0A 3PW8A 1TKOA 3BVIA 3Q4OA 3RBCA 4DYYA 3RD0A 2JD80 1H96A 1JIGA 4CMYA 3UOIA 3TA8A 4EVEA 2ZG7X 3Q4NA 3E6SA 5HJFA 2GS4A 3KA9A 4XGSA 4MJYA 2MGYA 3PVRA 5D8QA 2XJNA 4LQJA 5FFCA 2G38B 2Z5QA 2FL0A 4AM2A 5LG2A 4XKTA 5CMRA 2BK6A 3DBYA 1VEIA 1BFRA 3KWOA 1NFVA 5CMQA 4LYXA 4ERUA 5J8WA 5D8RA 1QGHA 5ERJA 1JKVA 1IESA 1JTSA 2V2NA 2V2PA 4YVZA 5GN8A 2XKQA 5LG8A 2VXXA 1J30A 1VEQA 3FRRA 3BVLA 3F39A 1TJOA 2RBDA 3AJPA 3IS8A 3PVYA 2V8UA 1LKPA 4M33A 4OYNA 1XZ1A 3IS7A 4TODA 3PW1A 2CN6A 3NP2X 3R2SA 1RYTA 3AK9A 3KA6A 5D8YA 3PW8C 2C6RA 2V15A 5K52A 3PVTA 3R2MA 4MUDA 2IU2A 1O9IA 3SE1A 4RC7A 4ZKXA 3KA4A 4XKUA 4RC5A 5K53A 4TOFA 2CN7A 2Y3QA 3AF9X 3F33A 4CYBA 2IY4A 3WNWA 4ML5A 5D8PA 1O9RA 4LPNA 2XJMA 4YXJA 4LYUA 3E1PA 3D19A 4M34A 5J9VA 1B71A 3R2RA 3RGDA 3N6OA 2Z5PA 4ZL6A 3MPSA 4CVPA 1LKMA 4CMYV 3F35A 2UX1A 4YKHA 3AF7X 1LKOA 4CVSA 2CHPA 2WWXB 3E1MA 3KA3A 3PVRB 4KXRB 1VELA 2FG8A 2X170 2QF9A 1FHAA 3A68A 1SOFA 2V2IA 2ITBA 3RE7A 3E1JA 4PGKA 4MN9A 3U90A 4MXPA 5GN8B 3VNXA 2AR0A 3O7SA 5JKLG 3F37A 3GVYA 2C2JA 2OH3A 2GYDA 5D8SA 2ZA6A 1LB3A 3L0MA 4ETRA 3PVYB 4TOHA 3C1YA 3EZ0A 5LBHA 1JKUA 4ZKWA 3F34A 4TW3A 3KHKA 2C2FA 2XJOA 3HL1A 4XKSA 5D8OA 1UMNA 3PW1B 3OGHA 3E1QA 1JREA 5JKMA 1NF4A 1KRQA 2V2RA 5ERKA
chains in the Genus database with same CATH topology
3BKNA 4P18A 4TO9A 4ITTA 3PVTB 4LPJA 4CVRA 2FKZA 5D8XA 4IWKA 1JI4A 3NP0X 4RC7B 2OC5A 4W4LB 3EGMA 2Z6MA 3HIUA 2WLAA 5J93A 4RC5B 4TOGA 3SHXA 4KVSA 1BG7A 1S2ZA 2WTLA 1VJXA 5JACA 3BVFA 4TOEA 5GU0X 3EZUA 3UFBA 3WVUA 3E2CA 3WVVA 3LKDA 4ZL5A 4CYAA 5GU2X 3H7GA 2WLUA 3VV9A 3PZAA 2CLUA 2CWLA 1RCDA 3T9JA 3UOFA 4DI0A 3ES3A 2CF7A 3BVKA 3IQ1A 1DVBA 3A9QA 2YJKA 4EVCA 5GU3X 1S3QA 3O7RA 1R03A 3UNOA 5J8SA 3PWFA 4DYZA 3WVWA 1N1QA 1RCCA 1ZS3A 4LQVA 3BT5A 5FFDA 3FSEA 4TOCA 1MFRA 3W54A 1RCGA 4REUA 4RC6A 4ZTTA 5FFAA 4LQHA 3KDQA 3R2KA 4DE6A 2V8TA 3F36A 2ZA7A 3BVEA 3KA8A 4Z5SA 2V2MA 5FFBA 5HU6D 5E2DA 4M35A 3ISEA 4LPMA 4MY7A 5C6FA 4CY9A 4KVQA 4II4A 3E1OA 1GWGA 5JDOA 3FVBA 4U3GA 2FZFA 5I4JA 5GU1X 1IERA 3AJQA 1YUXA 1DPSA 3GHQA 3JZ9A 2G4HA 4YXMA 3OJ5A 4TOBA 4DZ0A 1TKPA 1VLGA 2BJYA 3ERZA 1L8HA 4R42A 5HQOA 3GGZA 2C41A 4AM4A 3KX9A 4PGIA 3QZ3A 2V2SA 3E1NA 4Y08A 1DATA 4ZLWA 4A25A 1JYBA 1NF6A 3C23A 3KXUA 4E40A 2GYQA 3C21A 3QB9A 4QUWA 2C2UA 4ITWA 1JGCA 2VXIA 1Z4AA 4RC8A 4ISMA 4MKUA 4E6KA 1QYBA 1AEWA 3Q4QA 3GE4A 2YW6A 1F30A 2V2JA 4ZJKA 4ZKHA 3QHCA 2HR5A 3PWQA 1RCIA 3E6RA 2Z90A 2BW1A 1L8IA 3R2HA 3SH6A 5IX6A 4RC6B 1NNQA 2CIHA 1F33A 1YUZA 3FI6A 3E1LA 4X0JA 1JI5A 4PG1A 3JZAB 2FJCA 1MOJA 1BCFA 2XGWA 4TOAA 5CZUA 5LS9A 4M32A 3ISFA 1S30A 2IB0A 2N02A 1EUMA 3R2LA 3VVAA 3NOZX 3FRSA 2FFXJ 1UVHA 1YV1A 2W0OA 5FFEA 2ZA8A 1ZUJA 3M6JA 4II4B 3AJOA 5HJHA 1XZ3A 5AXSA 3RAVA 2YW7A 2VZBA 4IWJA 5FEJA 2JD60 3GGYA 2FG4A 4DASA 5JKLA 4IXKA 4EVBA 5JDOB 1Z6OM 2F7NA 2JD70 2V2OA 5GOUA 3QHBA 4DYXA 2Z5RA 5JKMG 2BKCA 2ZURX 2OKCA 3QD8A 1OTKA 2YJJA 2HTNA 1TK6A 3F38A 4DYUA 2ZG8X 1HRSA 2D5KA 3R2OA 2QQYA 3SIDA 3C1ZA 2ZG9X 4CVTA 3AK8A 4WJG4 2CLBA 2Y44A 3PWQC 1RCEA 1Z6OA 4KVRA 3AF8X 2FHAA 4ISPA 3V3KB 3QVDA 3Q4RA 4W4KB 2PYBA 1SQ3A 5E1UA 4AM5A 2CHIA 2V2LA 4EVDA 4ZMCA 3F32A 4Z3BA 2CEIA 4LQNA 4PG0A 3PW8A 1TKOA 3BVIA 3Q4OA 3RBCA 4DYYA 3RD0A 2JD80 1H96A 1JIGA 4CMYA 3UOIA 3TA8A 4EVEA 2ZG7X 3Q4NA 3E6SA 5HJFA 2GS4A 3KA9A 4XGSA 4MJYA 2MGYA 3PVRA 5D8QA 2XJNA 4LQJA 5FFCA 2G38B 2Z5QA 2FL0A 4AM2A 5LG2A 4XKTA 5CMRA 2BK6A 3DBYA 1VEIA 1BFRA 3KWOA 1NFVA 5CMQA 4LYXA 4ERUA 5J8WA 5D8RA 1QGHA 5ERJA 1JKVA 1IESA 1JTSA 2V2NA 2V2PA 4YVZA 5GN8A 2XKQA 5LG8A 2VXXA 1J30A 1VEQA 3FRRA 3BVLA 3F39A 1TJOA 2RBDA 3AJPA 3IS8A 3PVYA 2V8UA 1LKPA 4M33A 4OYNA 1XZ1A 3IS7A 4TODA 3PW1A 2CN6A 3NP2X 3R2SA 1RYTA 3AK9A 3KA6A 5D8YA 3PW8C 2C6RA 2V15A 5K52A 3PVTA 3R2MA 4MUDA 2IU2A 1O9IA 3SE1A 4RC7A 4ZKXA 3KA4A 4XKUA 4RC5A 5K53A 4TOFA 2CN7A 2Y3QA 3AF9X 3F33A 4CYBA 2IY4A 3WNWA 4ML5A 5D8PA 1O9RA 4LPNA 2XJMA 4YXJA 4LYUA 3E1PA 3D19A 4M34A 5J9VA 1B71A 3R2RA 3RGDA 3N6OA 2Z5PA 4ZL6A 3MPSA 4CVPA 1LKMA 4CMYV 3F35A 2UX1A 4YKHA 3AF7X 1LKOA 4CVSA 2CHPA 2WWXB 3E1MA 3KA3A 3PVRB 4KXRB 1VELA 2FG8A 2X170 2QF9A 1FHAA 3A68A 1SOFA 2V2IA 2ITBA 3RE7A 3E1JA 4PGKA 4MN9A 3U90A 4MXPA 5GN8B 3VNXA 2AR0A 3O7SA 5JKLG 3F37A 3GVYA 2C2JA 2OH3A 2GYDA 5D8SA 2ZA6A 1LB3A 3L0MA 4ETRA 3PVYB 4TOHA 3C1YA 3EZ0A 5LBHA 1JKUA 4ZKWA 3F34A 4TW3A 3KHKA 2C2FA 2XJOA 3HL1A 4XKSA 5D8OA 1UMNA 3PW1B 3OGHA 3E1QA 1JREA 5JKMA 1NF4A 1KRQA 2V2RA 5ERKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BKN A;  4P18 A;  4TO9 A;  4ITT A;  3PVT B;  4LPJ A;  4CVR A;  2FKZ A;  5D8X A;  4IWK A;  1JI4 A;  3NP0 X;  4RC7 B;  2OC5 A;  3EGM A;  2Z6M A;  3HIU A;  2WLA A;  5J93 A;  4RC5 B;  4TOG A;  3SHX A;  4KVS A;  1BG7 A;  1S2Z A;  2WTL A;  1VJX A;  5JAC A;  3BVF A;  4TOE A;  5GU0 X;  3EZU A;  3WVU A;  3E2C A;  3WVV A;  4ZL5 A;  4CYA A;  5GU2 X;  3H7G A;  2WLU A;  3PZA A;  2CLU A;  1RCD A;  3T9J A;  3UOF A;  4DI0 A;  3ES3 A;  2CF7 A;  3BVK A;  3IQ1 A;  1DVB A;  3A9Q A;  2YJK A;  4EVC A;  5GU3 X;  1S3Q A;  3O7R A;  1R03 A;  3UNO A;  5J8S A;  3PWF A;  4DYZ A;  3WVW A;  1N1Q A;  1RCC A;  1ZS3 A;  4LQV A;  3BT5 A;  5FFD A;  3FSE A;  4TOC A;  1MFR A;  1RCG A;  4REU A;  4RC6 A;  4ZTT A;  5FFA A;  4LQH A;  3R2K A;  4DE6 A;  3F36 A;  2ZA7 A;  3BVE A;  3KA8 A;  4Z5S A;  2V2M A;  5FFB A;  5E2D A;  4M35 A;  3ISE A;  4LPM A;  4MY7 A;  5C6F A;  4CY9 A;  4KVQ A;  4II4 A;  3E1O A;  1GWG A;  3FVB A;  4U3G A;  2FZF A;  5I4J A;  5GU1 X;  1IER A;  3AJQ A;  1YUX A;  1DPS A;  3GHQ A;  2G4H A;  3OJ5 A;  4TOB A;  4DZ0 A;  1TKP A;  1VLG A;  2BJY A;  3ERZ A;  1L8H A;  4R42 A;  5HQO A;  2C41 A;  4AM4 A;  3KX9 A;  4PGI A;  3QZ3 A;  2V2S A;  3E1N A;  4Y08 A;  1DAT A;  4ZLW A;  4A25 A;  1JYB A;  1NF6 A;  3KXU A;  2GYQ A;  3QB9 A;  4QUW A;  2C2U A;  4ITW A;  1JGC A;  2VXI A;  1Z4A A;  4RC8 A;  4ISM A;  4MKU A;  4E6K A;  1QYB A;  1AEW A;  3Q4Q A;  3GE4 A;  2YW6 A;  1F30 A;  2V2J A;  4ZJK A;  4ZKH A;  3QHC A;  2HR5 A;  3PWQ A;  1RCI A;  3E6R A;  2Z90 A;  2BW1 A;  1L8I A;  3R2H A;  3SH6 A;  5IX6 A;  4RC6 B;  1NNQ A;  2CIH A;  1F33 A;  1YUZ A;  3FI6 A;  3E1L A;  1JI5 A;  4PG1 A;  2FJC A;  1MOJ A;  1BCF A;  2XGW A;  4TOA A;  5CZU A;  5LS9 A;  4M32 A;  3ISF A;  1S30 A;  2IB0 A;  1EUM A;  3R2L A;  3NOZ X;  2FFX J;  1UVH A;  1YV1 A;  2W0O A;  5FFE A;  2ZA8 A;  1ZUJ A;  4II4 B;  5HJH A;  3AJO A;  3RAV A;  1XZ3 A;  5AXS A;  2YW7 A;  2VZB A;  4IWJ A;  5FEJ A;  2JD6 0;  2FG4 A;  4DAS A;  5JKL A;  4IXK A;  4EVB A;  1Z6O M;  2F7N A;  2JD7 0;  2V2O A;  5GOU A;  3QHB A;  4DYX A;  2Z5R A;  5JKM G;  2BKC A;  2ZUR X;  3QD8 A;  1OTK A;  2YJJ A;  2HTN A;  1TK6 A;  3F38 A;  4DYU A;  2ZG8 X;  1HRS A;  2D5K A;  3R2O A;  2QQY A;  3SID A;  2ZG9 X;  4CVT A;  3AK8 A;  2CLB A;  3PWQ C;  1RCE A;  1Z6O A;  4KVR A;  3AF8 X;  2FHA A;  4ISP A;  3QVD A;  3Q4R A;  2PYB A;  1SQ3 A;  5E1U A;  4AM5 A;  2CHI A;  2V2L A;  4EVD A;  4ZMC A;  3F32 A;  4Z3B A;  2CEI A;  4LQN A;  4PG0 A;  3PW8 A;  1TKO A;  3BVI A;  3Q4O A;  3RBC A;  4DYY A;  3RD0 A;  2JD8 0;  1H96 A;  1JIG A;  4CMY A;  3UOI A;  3TA8 A;  4EVE A;  2ZG7 X;  3Q4N A;  3E6S A;  5HJF A;  2GS4 A;  3KA9 A;  4XGS A;  4MJY A;  3PVR A;  5D8Q A;  2XJN A;  4LQJ A;  5FFC A;  2Z5Q A;  2FL0 A;  4AM2 A;  5LG2 A;  4XKT A;  5CMR A;  2BK6 A;  1VEI A;  1BFR A;  3KWO A;  1NFV A;  5CMQ A;  4LYX A;  4ERU A;  5J8W A;  5D8R A;  1QGH A;  5ERJ A;  1JKV A;  1IES A;  1JTS A;  2V2N A;  2V2P A;  5GN8 A;  2XKQ A;  5LG8 A;  2VXX A;  1J30 A;  1VEQ A;  3BVL A;  3F39 A;  1TJO A;  2RBD A;  3AJP A;  3IS8 A;  3PVY A;  1LKP A;  4M33 A;  4OYN A;  1XZ1 A;  3IS7 A;  4TOD A;  3PW1 A;  2CN6 A;  3NP2 X;  3R2S A;  1RYT A;  3AK9 A;  3KA6 A;  5D8Y A;  3PW8 C;  2C6R A;  2V15 A;  5K52 A;  3PVT A;  3R2M A;  4MUD A;  2IU2 A;  1O9I A;  3SE1 A;  4RC7 A;  4ZKX A;  3KA4 A;  4XKU A;  4RC5 A;  5K53 A;  4TOF A;  2CN7 A;  2Y3Q A;  3AF9 X;  3F33 A;  4CYB A;  2IY4 A;  3WNW A;  4ML5 A;  5D8P A;  1O9R A;  4LPN A;  2XJM A;  4LYU A;  3E1P A;  4M34 A;  5J9V A;  1B71 A;  3R2R A;  3RGD A;  2Z5P A;  4ZL6 A;  3MPS A;  4CVP A;  1LKM A;  4CMY V;  3F35 A;  2UX1 A;  4YKH A;  3AF7 X;  1LKO A;  4CVS A;  2CHP A;  3E1M A;  3KA3 A;  3PVR B;  1VEL A;  2FG8 A;  2X17 0;  2QF9 A;  1FHA A;  3A68 A;  1SOF A;  2V2I A;  2ITB A;  3RE7 A;  3E1J A;  4PGK A;  4MN9 A;  3U90 A;  5GN8 B;  3VNX A;  3O7S A;  5JKL G;  3F37 A;  3GVY A;  2C2J A;  2OH3 A;  2GYD A;  5D8S A;  2ZA6 A;  1LB3 A;  4ETR A;  3PVY B;  4TOH A;  3EZ0 A;  5LBH A;  1JKU A;  4ZKW A;  3F34 A;  4TW3 A;  2C2F A;  2XJO A;  3HL1 A;  4XKS A;  5D8O A;  1UMN A;  3PW1 B;  3OGH A;  3E1Q A;  1JRE A;  5JKM A;  1NF4 A;  1KRQ A;  2V2R A;  5ERK A; 
#chains in the Genus database with same CATH topology
 3BKN A;  4P18 A;  4TO9 A;  4ITT A;  3PVT B;  4LPJ A;  4CVR A;  2FKZ A;  5D8X A;  4IWK A;  1JI4 A;  3NP0 X;  4RC7 B;  2OC5 A;  4W4L B;  3EGM A;  2Z6M A;  3HIU A;  2WLA A;  5J93 A;  4RC5 B;  4TOG A;  3SHX A;  4KVS A;  1BG7 A;  1S2Z A;  2WTL A;  1VJX A;  5JAC A;  3BVF A;  4TOE A;  5GU0 X;  3EZU A;  3UFB A;  3WVU A;  3E2C A;  3WVV A;  3LKD A;  4ZL5 A;  4CYA A;  5GU2 X;  3H7G A;  2WLU A;  3VV9 A;  3PZA A;  2CLU A;  2CWL A;  1RCD A;  3T9J A;  3UOF A;  4DI0 A;  3ES3 A;  2CF7 A;  3BVK A;  3IQ1 A;  1DVB A;  3A9Q A;  2YJK A;  4EVC A;  5GU3 X;  1S3Q A;  3O7R A;  1R03 A;  3UNO A;  5J8S A;  3PWF A;  4DYZ A;  3WVW A;  1N1Q A;  1RCC A;  1ZS3 A;  4LQV A;  3BT5 A;  5FFD A;  3FSE A;  4TOC A;  1MFR A;  3W54 A;  1RCG A;  4REU A;  4RC6 A;  4ZTT A;  5FFA A;  4LQH A;  3KDQ A;  3R2K A;  4DE6 A;  2V8T A;  3F36 A;  2ZA7 A;  3BVE A;  3KA8 A;  4Z5S A;  2V2M A;  5FFB A;  5HU6 D;  5E2D A;  4M35 A;  3ISE A;  4LPM A;  4MY7 A;  5C6F A;  4CY9 A;  4KVQ A;  4II4 A;  3E1O A;  1GWG A;  5JDO A;  3FVB A;  4U3G A;  2FZF A;  5I4J A;  5GU1 X;  1IER A;  3AJQ A;  1YUX A;  1DPS A;  3GHQ A;  3JZ9 A;  2G4H A;  4YXM A;  3OJ5 A;  4TOB A;  4DZ0 A;  1TKP A;  1VLG A;  2BJY A;  3ERZ A;  1L8H A;  4R42 A;  5HQO A;  3GGZ A;  2C41 A;  4AM4 A;  3KX9 A;  4PGI A;  3QZ3 A;  2V2S A;  3E1N A;  4Y08 A;  1DAT A;  4ZLW A;  4A25 A;  1JYB A;  1NF6 A;  3C23 A;  3KXU A;  4E40 A;  2GYQ A;  3C21 A;  3QB9 A;  4QUW A;  2C2U A;  4ITW A;  1JGC A;  2VXI A;  1Z4A A;  4RC8 A;  4ISM A;  4MKU A;  4E6K A;  1QYB A;  1AEW A;  3Q4Q A;  3GE4 A;  2YW6 A;  1F30 A;  2V2J A;  4ZJK A;  4ZKH A;  3QHC A;  2HR5 A;  3PWQ A;  1RCI A;  3E6R A;  2Z90 A;  2BW1 A;  1L8I A;  3R2H A;  3SH6 A;  5IX6 A;  4RC6 B;  1NNQ A;  2CIH A;  1F33 A;  1YUZ A;  3FI6 A;  3E1L A;  4X0J A;  1JI5 A;  4PG1 A;  3JZA B;  2FJC A;  1MOJ A;  1BCF A;  2XGW A;  4TOA A;  5CZU A;  5LS9 A;  4M32 A;  3ISF A;  1S30 A;  2IB0 A;  2N02 A;  1EUM A;  3R2L A;  3VVA A;  3NOZ X;  3FRS A;  2FFX J;  1UVH A;  1YV1 A;  2W0O A;  5FFE A;  2ZA8 A;  1ZUJ A;  3M6J A;  4II4 B;  3AJO A;  5HJH A;  1XZ3 A;  5AXS A;  3RAV A;  2YW7 A;  2VZB A;  4IWJ A;  5FEJ A;  2JD6 0;  3GGY A;  2FG4 A;  4DAS A;  5JKL A;  4IXK A;  4EVB A;  5JDO B;  1Z6O M;  2F7N A;  2JD7 0;  2V2O A;  5GOU A;  3QHB A;  4DYX A;  2Z5R A;  5JKM G;  2BKC A;  2ZUR X;  2OKC A;  3QD8 A;  1OTK A;  2YJJ A;  2HTN A;  1TK6 A;  3F38 A;  4DYU A;  2ZG8 X;  1HRS A;  2D5K A;  3R2O A;  2QQY A;  3SID A;  3C1Z A;  2ZG9 X;  4CVT A;  3AK8 A;  4WJG 4;  2CLB A;  2Y44 A;  3PWQ C;  1RCE A;  1Z6O A;  4KVR A;  3AF8 X;  2FHA A;  4ISP A;  3V3K B;  3QVD A;  3Q4R A;  4W4K B;  2PYB A;  1SQ3 A;  5E1U A;  4AM5 A;  2CHI A;  2V2L A;  4EVD A;  4ZMC A;  3F32 A;  4Z3B A;  2CEI A;  4LQN A;  4PG0 A;  3PW8 A;  1TKO A;  3BVI A;  3Q4O A;  3RBC A;  4DYY A;  3RD0 A;  2JD8 0;  1H96 A;  1JIG A;  4CMY A;  3UOI A;  3TA8 A;  4EVE A;  2ZG7 X;  3Q4N A;  3E6S A;  5HJF A;  2GS4 A;  3KA9 A;  4XGS A;  4MJY A;  2MGY A;  3PVR A;  5D8Q A;  2XJN A;  4LQJ A;  5FFC A;  2G38 B;  2Z5Q A;  2FL0 A;  4AM2 A;  5LG2 A;  4XKT A;  5CMR A;  2BK6 A;  3DBY A;  1VEI A;  1BFR A;  3KWO A;  1NFV A;  5CMQ A;  4LYX A;  4ERU A;  5J8W A;  5D8R A;  1QGH A;  5ERJ A;  1JKV A;  1IES A;  1JTS A;  2V2N A;  2V2P A;  4YVZ A;  5GN8 A;  2XKQ A;  5LG8 A;  2VXX A;  1J30 A;  1VEQ A;  3FRR A;  3BVL A;  3F39 A;  1TJO A;  2RBD A;  3AJP A;  3IS8 A;  3PVY A;  2V8U A;  1LKP A;  4M33 A;  4OYN A;  1XZ1 A;  3IS7 A;  4TOD A;  3PW1 A;  2CN6 A;  3NP2 X;  3R2S A;  1RYT A;  3AK9 A;  3KA6 A;  5D8Y A;  3PW8 C;  2C6R A;  2V15 A;  5K52 A;  3PVT A;  3R2M A;  4MUD A;  2IU2 A;  1O9I A;  3SE1 A;  4RC7 A;  4ZKX A;  3KA4 A;  4XKU A;  4RC5 A;  5K53 A;  4TOF A;  2CN7 A;  2Y3Q A;  3AF9 X;  3F33 A;  4CYB A;  2IY4 A;  3WNW A;  4ML5 A;  5D8P A;  1O9R A;  4LPN A;  2XJM A;  4YXJ A;  4LYU A;  3E1P A;  3D19 A;  4M34 A;  5J9V A;  1B71 A;  3R2R A;  3RGD A;  3N6O A;  2Z5P A;  4ZL6 A;  3MPS A;  4CVP A;  1LKM A;  4CMY V;  3F35 A;  2UX1 A;  4YKH A;  3AF7 X;  1LKO A;  4CVS A;  2CHP A;  2WWX B;  3E1M A;  3KA3 A;  3PVR B;  4KXR B;  1VEL A;  2FG8 A;  2X17 0;  2QF9 A;  1FHA A;  3A68 A;  1SOF A;  2V2I A;  2ITB A;  3RE7 A;  3E1J A;  4PGK A;  4MN9 A;  3U90 A;  4MXP A;  5GN8 B;  3VNX A;  2AR0 A;  3O7S A;  5JKL G;  3F37 A;  3GVY A;  2C2J A;  2OH3 A;  2GYD A;  5D8S A;  2ZA6 A;  1LB3 A;  3L0M A;  4ETR A;  3PVY B;  4TOH A;  3C1Y A;  3EZ0 A;  5LBH A;  1JKU A;  4ZKW A;  3F34 A;  4TW3 A;  3KHK A;  2C2F A;  2XJO A;  3HL1 A;  4XKS A;  5D8O A;  1UMN A;  3PW1 B;  3OGH A;  3E1Q A;  1JRE A;  5JKM A;  1NF4 A;  1KRQ A;  2V2R A;  5ERK A; 
#chains in the Genus database with same CATH homology
 3BKN A;  4P18 A;  4TO9 A;  4ITT A;  3PVT B;  4LPJ A;  4CVR A;  2FKZ A;  5D8X A;  4IWK A;  1JI4 A;  3NP0 X;  4RC7 B;  2OC5 A;  4W4L B;  3EGM A;  2Z6M A;  3HIU A;  2WLA A;  5J93 A;  4RC5 B;  4TOG A;  3SHX A;  4KVS A;  1BG7 A;  1S2Z A;  2WTL A;  1VJX A;  5JAC A;  3BVF A;  4TOE A;  5GU0 X;  3EZU A;  3UFB A;  3WVU A;  3E2C A;  3WVV A;  3LKD A;  4ZL5 A;  4CYA A;  5GU2 X;  3H7G A;  2WLU A;  3VV9 A;  3PZA A;  2CLU A;  2CWL A;  1RCD A;  3T9J A;  3UOF A;  4DI0 A;  3ES3 A;  2CF7 A;  3BVK A;  3IQ1 A;  1DVB A;  3A9Q A;  2YJK A;  4EVC A;  5GU3 X;  1S3Q A;  3O7R A;  1R03 A;  3UNO A;  5J8S A;  3PWF A;  4DYZ A;  3WVW A;  1N1Q A;  1RCC A;  1ZS3 A;  4LQV A;  3BT5 A;  5FFD A;  3FSE A;  4TOC A;  1MFR A;  3W54 A;  1RCG A;  4REU A;  4RC6 A;  4ZTT A;  5FFA A;  4LQH A;  3KDQ A;  3R2K A;  4DE6 A;  2V8T A;  3F36 A;  2ZA7 A;  3BVE A;  3KA8 A;  4Z5S A;  2V2M A;  5FFB A;  5HU6 D;  5E2D A;  4M35 A;  3ISE A;  4LPM A;  4MY7 A;  5C6F A;  4CY9 A;  4KVQ A;  4II4 A;  3E1O A;  1GWG A;  5JDO A;  3FVB A;  4U3G A;  2FZF A;  5I4J A;  5GU1 X;  1IER A;  3AJQ A;  1YUX A;  1DPS A;  3GHQ A;  3JZ9 A;  2G4H A;  4YXM A;  3OJ5 A;  4TOB A;  4DZ0 A;  1TKP A;  1VLG A;  2BJY A;  3ERZ A;  1L8H A;  4R42 A;  5HQO A;  3GGZ A;  2C41 A;  4AM4 A;  3KX9 A;  4PGI A;  3QZ3 A;  2V2S A;  3E1N A;  4Y08 A;  1DAT A;  4ZLW A;  4A25 A;  1JYB A;  1NF6 A;  3C23 A;  3KXU A;  4E40 A;  2GYQ A;  3C21 A;  3QB9 A;  4QUW A;  2C2U A;  4ITW A;  1JGC A;  2VXI A;  1Z4A A;  4RC8 A;  4ISM A;  4MKU A;  4E6K A;  1QYB A;  1AEW A;  3Q4Q A;  3GE4 A;  2YW6 A;  1F30 A;  2V2J A;  4ZJK A;  4ZKH A;  3QHC A;  2HR5 A;  3PWQ A;  1RCI A;  3E6R A;  2Z90 A;  2BW1 A;  1L8I A;  3R2H A;  3SH6 A;  5IX6 A;  4RC6 B;  1NNQ A;  2CIH A;  1F33 A;  1YUZ A;  3FI6 A;  3E1L A;  4X0J A;  1JI5 A;  4PG1 A;  3JZA B;  2FJC A;  1MOJ A;  1BCF A;  2XGW A;  4TOA A;  5CZU A;  5LS9 A;  4M32 A;  3ISF A;  1S30 A;  2IB0 A;  2N02 A;  1EUM A;  3R2L A;  3VVA A;  3NOZ X;  3FRS A;  2FFX J;  1UVH A;  1YV1 A;  2W0O A;  5FFE A;  2ZA8 A;  1ZUJ A;  3M6J A;  4II4 B;  3AJO A;  5HJH A;  1XZ3 A;  5AXS A;  3RAV A;  2YW7 A;  2VZB A;  4IWJ A;  5FEJ A;  2JD6 0;  3GGY A;  2FG4 A;  4DAS A;  5JKL A;  4IXK A;  4EVB A;  5JDO B;  1Z6O M;  2F7N A;  2JD7 0;  2V2O A;  5GOU A;  3QHB A;  4DYX A;  2Z5R A;  5JKM G;  2BKC A;  2ZUR X;  2OKC A;  3QD8 A;  1OTK A;  2YJJ A;  2HTN A;  1TK6 A;  3F38 A;  4DYU A;  2ZG8 X;  1HRS A;  2D5K A;  3R2O A;  2QQY A;  3SID A;  3C1Z A;  2ZG9 X;  4CVT A;  3AK8 A;  4WJG 4;  2CLB A;  2Y44 A;  3PWQ C;  1RCE A;  1Z6O A;  4KVR A;  3AF8 X;  2FHA A;  4ISP A;  3V3K B;  3QVD A;  3Q4R A;  4W4K B;  2PYB A;  1SQ3 A;  5E1U A;  4AM5 A;  2CHI A;  2V2L A;  4EVD A;  4ZMC A;  3F32 A;  4Z3B A;  2CEI A;  4LQN A;  4PG0 A;  3PW8 A;  1TKO A;  3BVI A;  3Q4O A;  3RBC A;  4DYY A;  3RD0 A;  2JD8 0;  1H96 A;  1JIG A;  4CMY A;  3UOI A;  3TA8 A;  4EVE A;  2ZG7 X;  3Q4N A;  3E6S A;  5HJF A;  2GS4 A;  3KA9 A;  4XGS A;  4MJY A;  2MGY A;  3PVR A;  5D8Q A;  2XJN A;  4LQJ A;  5FFC A;  2G38 B;  2Z5Q A;  2FL0 A;  4AM2 A;  5LG2 A;  4XKT A;  5CMR A;  2BK6 A;  3DBY A;  1VEI A;  1BFR A;  3KWO A;  1NFV A;  5CMQ A;  4LYX A;  4ERU A;  5J8W A;  5D8R A;  1QGH A;  5ERJ A;  1JKV A;  1IES A;  1JTS A;  2V2N A;  2V2P A;  4YVZ A;  5GN8 A;  2XKQ A;  5LG8 A;  2VXX A;  1J30 A;  1VEQ A;  3FRR A;  3BVL A;  3F39 A;  1TJO A;  2RBD A;  3AJP A;  3IS8 A;  3PVY A;  2V8U A;  1LKP A;  4M33 A;  4OYN A;  1XZ1 A;  3IS7 A;  4TOD A;  3PW1 A;  2CN6 A;  3NP2 X;  3R2S A;  1RYT A;  3AK9 A;  3KA6 A;  5D8Y A;  3PW8 C;  2C6R A;  2V15 A;  5K52 A;  3PVT A;  3R2M A;  4MUD A;  2IU2 A;  1O9I A;  3SE1 A;  4RC7 A;  4ZKX A;  3KA4 A;  4XKU A;  4RC5 A;  5K53 A;  4TOF A;  2CN7 A;  2Y3Q A;  3AF9 X;  3F33 A;  4CYB A;  2IY4 A;  3WNW A;  4ML5 A;  5D8P A;  1O9R A;  4LPN A;  2XJM A;  4YXJ A;  4LYU A;  3E1P A;  3D19 A;  4M34 A;  5J9V A;  1B71 A;  3R2R A;  3RGD A;  3N6O A;  2Z5P A;  4ZL6 A;  3MPS A;  4CVP A;  1LKM A;  4CMY V;  3F35 A;  2UX1 A;  4YKH A;  3AF7 X;  1LKO A;  4CVS A;  2CHP A;  2WWX B;  3E1M A;  3KA3 A;  3PVR B;  4KXR B;  1VEL A;  2FG8 A;  2X17 0;  2QF9 A;  1FHA A;  3A68 A;  1SOF A;  2V2I A;  2ITB A;  3RE7 A;  3E1J A;  4PGK A;  4MN9 A;  3U90 A;  4MXP A;  5GN8 B;  3VNX A;  2AR0 A;  3O7S A;  5JKL G;  3F37 A;  3GVY A;  2C2J A;  2OH3 A;  2GYD A;  5D8S A;  2ZA6 A;  1LB3 A;  3L0M A;  4ETR A;  3PVY B;  4TOH A;  3C1Y A;  3EZ0 A;  5LBH A;  1JKU A;  4ZKW A;  3F34 A;  4TW3 A;  3KHK A;  2C2F A;  2XJO A;  3HL1 A;  4XKS A;  5D8O A;  1UMN A;  3PW1 B;  3OGH A;  3E1Q A;  1JRE A;  5JKM A;  1NF4 A;  1KRQ A;  2V2R A;  5ERK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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