2XSO | Genus

Total Genus 138

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	138
sequence length	442
structure length	433
Chain Sequence	NWTPEAIRGLVDQEKGLLDPRIYADQSLYELELERVFGRSWLLLGHESHVPETGDFLATYMGEDPVVMVRQKDKSIKVFLNQCRHRGMRICRSDAGNAKAFTCSYHGWAYDIAGKLVNVPFEKEAFFDKAEWGPLQARVATYKGLVFANWDVQAPDLETYLGDARPYMDVMLDRTPAGTVAIGGMQKWVIPCNWKFAAEQFCSDMYHAGTTTHLSGILAGIPPEMDLSQAQIPTKGNQFRAAWGGHGSGWYVDEPGSLLAVMGPKVTQYWTEGPAAELAEQRLGHTGMPVRRMVGQHMTIFPTCSFLPAMNNIRIWHPRGPNEIEVWAFTLVDADAPAEIKEEYRRHNIRNFSAGGVFEQDDGENWVEIQKGLRGYKAKSQPLNAQMGLGRSQTGHPDFPGNVGYVYAEEAARGMYHHWMRMMSEPSWATLKP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Oxidoreductase
source organism	Burkholderia xenovorans
publication title	Structural Insight Into the Expanded Pcb-Degrading Abilities of a Biphenyl Dioxygenase Obtained by Directed Evolution. pubmed doi rcsb
molecule keywords	BIPHENYL DIOXYGENASE SUBUNIT ALPHA
total genus	138
structure length	433
sequence length	442
chains with identical sequence	C, E, G, I, K, M, O, Q, S, U, W
ec nomenclature	ec 1.14.12.18: Biphenyl 2,3-dioxygenase.
pdb deposition date	2010-09-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00355	Rieske	Rieske [2Fe-2S] domain
A	PF00848	Ring_hydroxyl_A	Ring hydroxylating alpha subunit (catalytic domain)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.102.10.10	Mainly Beta	3-layer Sandwich	Rieske Iron-sulfur Protein	Rieske [2Fe-2S] iron-sulphur domain	2xsoA02
3.90.380.10	Alpha Beta	Alpha-Beta Complex	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1	Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1	2xsoA01

1EZVE 4P1BH 3H1HE 2BMQA 3GZYA 1SQVE 1EG9A 4NBFA 1G8JB 2Q3WA 3GCEA 2A06E 2E76D 3VCAA 4NBGA 2XRXA 2JO6A 4NBDA 5CXMA 1Z03A 1UUVA 2B24A 4QUPA 4PV1D 1PPJE 2QJYC 1L0NE 2JZAA 4EMJB 2XR8A 3H1IE 3C0DA 3FOUA 4NBCD 2BCCE 2HMLA 3D89A 3GL0A 1O7HA 2I7FA 2E74D 4HM4A 4AIVA 4NB9A 1O7WA 4NBHD 2HMMA 2DE7D 4NBED 3GB4A 1UUWA 2NVGA 3L72E 3AZCA 4PD4E 2DE7A 5KLIC 4NBFD 2XSOA 1O7MA 3H1KE 4HM2A 3TGUE 2XSHA 2IBZE 2DE6A 1ULJA 3L75E 3VMIA 4NBGD 4NBDD 3H1LE 3DQYA 1FQTA 1SJGA 2YIUC 1RFSA 1NTME 4QDFB 4QURA 4HKVA 2QJKC 2NVFA 2BMRA 2NWFA 4NBBA 2FYNC 3VMHA 1P84E 4NB9D 2HMKA 3CX5E 2BMOA 2YVJB 4H44D 4HM1A 2YFJA 2DE5A 1KB9E 1O7NA 1NTZE 2NUKA 4HM6A 4NBAA 3L70E 4NBHA 1RIEA 4OGQD 2NVEA 1BCCE 4H0LD 4QUQA 2DE6D 4HM8A 3VMID 4QDFA 2E4PA 2E4QA 2ZT9D 1PP9E 1NYKA 1JM1A 3CXHE 4NBEA 1NDOA 4QDCA 4NB8D 5AEUA 3VMGA 3GTEA 2NUMA 2GBXA 5HL4A 4NBBD 4QCKA 3VMHD 2YFLA 1G8KB 4NB8A 2E75D 1ZRTE 3GKEA 3GOBA 3BCCE 4HM7A 4HM0A 3L74E 3N0QA 1L0LE 2DE5D 2HMOA 2QPZA 3CWBE 4U3FE 1Z02A 4NBAD 4H13D 1BE3E 1NTKE 1VM9A 1WW9A 1VF5D 3EN1A 1Q90C 2HMJA 3GTSA 5KKZC 1SQXE 1NU1E 1SQBE 2FYUE 2ZYLA 2B1XA 4HM5A 2HMNA 4AAYB 3VMGD 2GBWA 5BOKA 2YFIA 3GZXA 4HJLA 1KYOE 3GCFA 5AEWA 2D2CD 3VCPA 3L71E 1ULIA 3L73E 2CKFA 4P1CH 1O7GA 1VCKA 3H1JE 1SQQE 3GKQA 5KLVE 1Z01A 4NBCA 1SQPE 3GL2A 1O7PA 4QDDA 4HM3A 2QJPC 3EQQA 1WQLA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1EZV E;  4P1B H;  3H1H E;  2BMQ A;  3GZY A;  1SQV E;  1EG9 A;  4NBF A;  1G8J B;  2Q3W A;  3GCE A;  2A06 E;  2E76 D;  3VCA A;  4NBG A;  2XRX A;  2JO6 A;  4NBD A;  5CXM A;  1Z03 A;  1UUV A;  2B24 A;  4QUP A;  4PV1 D;  1PPJ E;  2QJY C;  1L0N E;  2JZA A;  4EMJ B;  2XR8 A;  3H1I E;  3C0D A;  3FOU A;  4NBC D;  2BCC E;  2HML A;  3D89 A;  3GL0 A;  1O7H A;  2I7F A;  2E74 D;  4HM4 A;  4AIV A;  4NB9 A;  1O7W A;  4NBH D;  2HMM A;  2DE7 D;  4NBE D;  3GB4 A;  1UUW A;  2NVG A;  3L72 E;  3AZC A;  4PD4 E;  2DE7 A;  5KLI C;  4NBF D;  2XSO A;  1O7M A;  3H1K E;  4HM2 A;  3TGU E;  2XSH A;  2IBZ E;  2DE6 A;  1ULJ A;  3L75 E;  3VMI A;  4NBG D;  4NBD D;  3H1L E;  3DQY A;  1FQT A;  1SJG A;  2YIU C;  1RFS A;  1NTM E;  4QDF B;  4QUR A;  4HKV A;  2QJK C;  2NVF A;  2BMR A;  2NWF A;  4NBB A;  2FYN C;  3VMH A;  1P84 E;  4NB9 D;  2HMK A;  3CX5 E;  2BMO A;  2YVJ B;  4H44 D;  4HM1 A;  2YFJ A;  2DE5 A;  1KB9 E;  1O7N A;  1NTZ E;  2NUK A;  4HM6 A;  4NBA A;  3L70 E;  4NBH A;  1RIE A;  4OGQ D;  2NVE A;  1BCC E;  4H0L D;  4QUQ A;  2DE6 D;  4HM8 A;  3VMI D;  4QDF A;  2E4P A;  2E4Q A;  2ZT9 D;  1PP9 E;  1NYK A;  1JM1 A;  3CXH E;  4NBE A;  1NDO A;  4QDC A;  4NB8 D;  5AEU A;  3VMG A;  3GTE A;  2NUM A;  2GBX A;  5HL4 A;  4NBB D;  4QCK A;  3VMH D;  2YFL A;  1G8K B;  4NB8 A;  2E75 D;  1ZRT E;  3GKE A;  3GOB A;  3BCC E;  4HM7 A;  4HM0 A;  3L74 E;  3N0Q A;  1L0L E;  2DE5 D;  2HMO A;  2QPZ A;  3CWB E;  4U3F E;  1Z02 A;  4NBA D;  4H13 D;  1BE3 E;  1NTK E;  1VM9 A;  1WW9 A;  1VF5 D;  3EN1 A;  1Q90 C;  2HMJ A;  3GTS A;  5KKZ C;  1SQX E;  1NU1 E;  1SQB E;  2FYU E;  2ZYL A;  2B1X A;  4HM5 A;  2HMN A;  4AAY B;  3VMG D;  2GBW A;  5BOK A;  2YFI A;  3GZX A;  4HJL A;  1KYO E;  3GCF A;  5AEW A;  2D2C D;  3VCP A;  3L71 E;  1ULI A;  3L73 E;  2CKF A;  4P1C H;  1O7G A;  1VCK A;  3H1J E;  1SQQ E;  3GKQ A;  5KLV E;  1Z01 A;  4NBC A;  1SQP E;  3GL2 A;  1O7P A;  4QDD A;  4HM3 A;  2QJP C;  3EQQ A;  1WQL A; 
#chains in the Genus database with same CATH topology
 1EZV E;  4P1B H;  3H1H E;  2BMQ A;  3GZY A;  1SQV E;  1EG9 A;  4NBF A;  1G8J B;  2Q3W A;  3GCE A;  2A06 E;  2E76 D;  3VCA A;  4NBG A;  2XRX A;  2JO6 A;  4NBD A;  5CXM A;  1Z03 A;  1UUV A;  2B24 A;  4QUP A;  4PV1 D;  1PPJ E;  2QJY C;  1L0N E;  2JZA A;  4EMJ B;  2XR8 A;  3H1I E;  3C0D A;  3FOU A;  4NBC D;  2BCC E;  2HML A;  3D89 A;  3GL0 A;  1O7H A;  2I7F A;  2E74 D;  4HM4 A;  4AIV A;  4NB9 A;  1O7W A;  4NBH D;  2HMM A;  2DE7 D;  4NBE D;  3GB4 A;  1UUW A;  2NVG A;  3L72 E;  3AZC A;  4PD4 E;  2DE7 A;  5KLI C;  4NBF D;  2XSO A;  1O7M A;  3H1K E;  4HM2 A;  3TGU E;  2XSH A;  2IBZ E;  2DE6 A;  1ULJ A;  3L75 E;  3VMI A;  4NBG D;  4NBD D;  3H1L E;  3DQY A;  1FQT A;  1SJG A;  2YIU C;  1RFS A;  1NTM E;  4QDF B;  4QUR A;  4HKV A;  2QJK C;  2NVF A;  2BMR A;  2NWF A;  4NBB A;  2FYN C;  3VMH A;  1P84 E;  4NB9 D;  2HMK A;  3CX5 E;  2BMO A;  2YVJ B;  4H44 D;  4HM1 A;  2YFJ A;  2DE5 A;  1KB9 E;  1O7N A;  1NTZ E;  2NUK A;  4HM6 A;  4NBA A;  3L70 E;  4NBH A;  1RIE A;  4OGQ D;  2NVE A;  1BCC E;  4H0L D;  4QUQ A;  2DE6 D;  4HM8 A;  3VMI D;  4QDF A;  2E4P A;  2E4Q A;  2ZT9 D;  1PP9 E;  1NYK A;  1JM1 A;  3CXH E;  4NBE A;  1NDO A;  4QDC A;  4NB8 D;  5AEU A;  3VMG A;  3GTE A;  2NUM A;  2GBX A;  5HL4 A;  4NBB D;  4QCK A;  3VMH D;  2YFL A;  1G8K B;  4NB8 A;  2E75 D;  1ZRT E;  3GKE A;  3GOB A;  3BCC E;  4HM7 A;  4HM0 A;  3L74 E;  3N0Q A;  1L0L E;  2DE5 D;  2HMO A;  2QPZ A;  3CWB E;  4U3F E;  1Z02 A;  4NBA D;  4H13 D;  1BE3 E;  1NTK E;  1VM9 A;  1WW9 A;  1VF5 D;  3EN1 A;  1Q90 C;  2HMJ A;  3GTS A;  5KKZ C;  1SQX E;  1NU1 E;  1SQB E;  2FYU E;  2ZYL A;  2B1X A;  4HM5 A;  2HMN A;  4AAY B;  3VMG D;  2GBW A;  5BOK A;  2YFI A;  3GZX A;  4HJL A;  1KYO E;  3GCF A;  5AEW A;  2D2C D;  3VCP A;  3L71 E;  1ULI A;  3L73 E;  2CKF A;  4P1C H;  1O7G A;  1VCK A;  3H1J E;  1SQQ E;  3GKQ A;  5KLV E;  1Z01 A;  4NBC A;  1SQP E;  3GL2 A;  1O7P A;  4QDD A;  4HM3 A;  2QJP C;  3EQQ A;  1WQL A; 
#chains in the Genus database with same CATH homology
 1EZV E;  4P1B H;  3H1H E;  2BMQ A;  3GZY A;  1SQV E;  1EG9 A;  4NBF A;  1G8J B;  2Q3W A;  3GCE A;  2A06 E;  2E76 D;  3VCA A;  4NBG A;  2XRX A;  2JO6 A;  4NBD A;  5CXM A;  1Z03 A;  1UUV A;  2B24 A;  4QUP A;  4PV1 D;  1PPJ E;  2QJY C;  1L0N E;  2JZA A;  4EMJ B;  2XR8 A;  3H1I E;  3C0D A;  3FOU A;  4NBC D;  2BCC E;  2HML A;  3D89 A;  3GL0 A;  1O7H A;  2I7F A;  2E74 D;  4HM4 A;  4AIV A;  4NB9 A;  1O7W A;  4NBH D;  2HMM A;  2DE7 D;  4NBE D;  3GB4 A;  1UUW A;  2NVG A;  3L72 E;  3AZC A;  4PD4 E;  2DE7 A;  5KLI C;  4NBF D;  2XSO A;  1O7M A;  3H1K E;  4HM2 A;  3TGU E;  2XSH A;  2IBZ E;  2DE6 A;  1ULJ A;  3L75 E;  3VMI A;  4NBG D;  4NBD D;  3H1L E;  3DQY A;  1FQT A;  1SJG A;  2YIU C;  1RFS A;  1NTM E;  4QDF B;  4QUR A;  4HKV A;  2QJK C;  2NVF A;  2BMR A;  2NWF A;  4NBB A;  2FYN C;  3VMH A;  1P84 E;  4NB9 D;  2HMK A;  3CX5 E;  2BMO A;  2YVJ B;  4H44 D;  4HM1 A;  2YFJ A;  2DE5 A;  1KB9 E;  1O7N A;  1NTZ E;  2NUK A;  4HM6 A;  4NBA A;  3L70 E;  4NBH A;  1RIE A;  4OGQ D;  2NVE A;  1BCC E;  4H0L D;  4QUQ A;  2DE6 D;  4HM8 A;  3VMI D;  4QDF A;  2E4P A;  2E4Q A;  2ZT9 D;  1PP9 E;  1NYK A;  1JM1 A;  3CXH E;  4NBE A;  1NDO A;  4QDC A;  4NB8 D;  5AEU A;  3VMG A;  3GTE A;  2NUM A;  2GBX A;  5HL4 A;  4NBB D;  4QCK A;  3VMH D;  2YFL A;  1G8K B;  4NB8 A;  2E75 D;  1ZRT E;  3GKE A;  3GOB A;  3BCC E;  4HM7 A;  4HM0 A;  3L74 E;  3N0Q A;  1L0L E;  2DE5 D;  2HMO A;  2QPZ A;  3CWB E;  4U3F E;  1Z02 A;  4NBA D;  4H13 D;  1BE3 E;  1NTK E;  1VM9 A;  1WW9 A;  1VF5 D;  3EN1 A;  1Q90 C;  2HMJ A;  3GTS A;  5KKZ C;  1SQX E;  1NU1 E;  1SQB E;  2FYU E;  2ZYL A;  2B1X A;  4HM5 A;  2HMN A;  4AAY B;  3VMG D;  2GBW A;  5BOK A;  2YFI A;  3GZX A;  4HJL A;  1KYO E;  3GCF A;  5AEW A;  2D2C D;  3VCP A;  3L71 E;  1ULI A;  3L73 E;  2CKF A;  4P1C H;  1O7G A;  1VCK A;  3H1J E;  1SQQ E;  3GKQ A;  5KLV E;  1Z01 A;  4NBC A;  1SQP E;  3GL2 A;  1O7P A;  4QDD A;  4HM3 A;  2QJP C;  3EQQ A;  1WQL A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2XSOA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations