2HMLA

Crystal structure of the naphthalene 1,2-dioxygenase f352v mutant bound to phenanthrene.
Total Genus 162
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
162
sequence length
446
structure length
446
Chain Sequence
MNYNNKILVSESGLSQKHLIHGDEELFQHELKTIFARNWLFLTHDSLIPAPGDYVTAKMGIDEVIVSRQNDGSIRAFLNVCRHRGKTLVSVEAGNAKGFVCSYHGWGFGSNGELQSVPFEKDLYGESLNKKCLGLKEVARVESFHGFIYGCFDQEAPPLMDYLGDAAWYLEPMFKHSGGLELVGPPGKVVIKANWKAPAENFVGDAYHVGWTHASSLRSGESIFSSLAGNAALPPEGAGLQMTSKYGSGMGVLWDGYSGVHSADLVPELMAFGGAKQERLNKEIGDVRARIYRSHLNCTVFPNNSMLTCSGVFKVWNPIDANTTEVWTYAIVEKDMPEDLKRRLADSVQRTVGPAGFWESDDNDNMETASQNGKKYQSRDSDLLSNLGFGEDVYGDAVYPGVVGKSAIGETSYRGFYRAYQAHVSSSNWAEFEHASSTWHTELTKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for regioselectivity and stereoselectivity of product formation by naphthalene 1,2-dioxygenase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Pseudomonas sp.
molecule keywords Naphthalene 1,2-dioxygenase alpha subunit
total genus 162
structure length 446
sequence length 446
ec nomenclature ec 1.14.12.12: Naphthalene 1,2-dioxygenase.
pdb deposition date 2006-07-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00355 Rieske Rieske [2Fe-2S] domain
A PF00848 Ring_hydroxyl_A Ring hydroxylating alpha subunit (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domain 2hmlA02
3.90.380.10 Alpha Beta Alpha-Beta Complex Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 2hmlA01
4HM6A 1NYKA 2ZT9D 2BMRA 2QJYC 3CXHE 5KLIC 4NBBA 4NBBD 2BCCE 5BOKA 2GBXA 3EN1A 1NTME 1VM9A 4H44D 4NBHA 4NBHD 1O7GA 2NVEA 2ZYLA 2HMOA 2D2CD 1G8JB 4HM7A 2FYUE 1UUVA 3GTEA 2YIUC 2HMLA 4NB8A 2B24A 4NB8D 2FYNC 1BE3E 3L73E 1Z02A 1ULJA 3GOBA 2NVGA 2XSHA 4AIVA 4NBEA 1FQTA 4NBED 4H0LD 4QDCA 1NTKE 5CXMA 3H1KE 3CWBE 1P84E 2DE7A 2A06E 2DE7D 4H13D 3GZYA 1L0NE 2NVFA 4HM3A 4HM2A 2HMMA 3H1HE 4QDFA 2XSOA 1WW9A 3DQYA 2JZAA 3AZCA 2NUMA 2GBWA 4HKVA 3H1IE 2E76D 4P1CH 2NWFA 1PP9E 2DE5A 1EG9A 2YFJA 3EQQA 2BMQA 3N0QA 1NDOA 1Z03A 1WQLA 4NBDA 4NBDD 5KKZC 3GL2A 4NBFA 4P1BH 4NBFD 3GKQA 3C0DA 3CX5E 4EMJB 3VMIA 1EZVE 1SQQE 3VMID 2E4QA 1VCKA 1ZRTE 2DE6A 2DE6D 1BCCE 4U3FE 2NUKA 1RFSA 2E4PA 4PD4E 2XRXA 4AAYB 5HL4A 2YVJB 1O7NA 1KB9E 3L72E 1NTZE 2QJKC 1O7HA 1SJGA 5AEWA 5KLVE 4HM1A 2DE5D 3H1LE 3GZXA 2JO6A 3VCPA 2HMNA 2YFLA 1JM1A 3H1JE 2B1XA 4NBAA 3BCCE 3L70E 4HM8A 4HJLA 1L0LE 1ULIA 1G8KB 4HM0A 3D89A 5AEUA 1PPJE 1SQXE 4QUQA 2Q3WA 1Q90C 1Z01A 3L75E 1SQBE 4QUPA 4QDFB 1O7PA 4PV1D 2I7FA 2QJPC 2QPZA 3L74E 4NB9A 4NB9D 4QDDA 3GTSA 3GB4A 1O7MA 3GCEA 3L71E 2XR8A 4NBGA 4NBGD 1O7WA 2HMJA 4NBCD 3VMHD 3TGUE 4NBCA 1RIEA 4QURA 3VMHA 4QCKA 4HM5A 1SQVE 2HMKA 3VMGA 3VMGD 3FOUA 1UUWA 2E75D 2E74D 3GKEA 1KYOE 2CKFA 2BMOA 4OGQD 1VF5D 3GL0A 4HM4A 1NU1E 3GCFA 1SQPE 2YFIA 3VCAA 4NBAD 2IBZE
chains in the Genus database with same CATH superfamily
4HM6A 1NYKA 2ZT9D 2BMRA 2QJYC 3CXHE 5KLIC 4NBBA 4NBBD 2BCCE 5BOKA 2GBXA 3EN1A 1NTME 1VM9A 4H44D 4NBHA 4NBHD 1O7GA 2NVEA 2ZYLA 2HMOA 2D2CD 1G8JB 4HM7A 2FYUE 1UUVA 3GTEA 2YIUC 2HMLA 4NB8A 2B24A 4NB8D 2FYNC 1BE3E 3L73E 1Z02A 1ULJA 3GOBA 2NVGA 2XSHA 4AIVA 4NBEA 1FQTA 4NBED 4H0LD 4QDCA 1NTKE 5CXMA 3H1KE 3CWBE 1P84E 2DE7A 2A06E 2DE7D 4H13D 3GZYA 1L0NE 2NVFA 4HM3A 4HM2A 2HMMA 3H1HE 4QDFA 2XSOA 1WW9A 3DQYA 2JZAA 3AZCA 2NUMA 2GBWA 4HKVA 3H1IE 2E76D 4P1CH 2NWFA 1PP9E 2DE5A 1EG9A 2YFJA 3EQQA 2BMQA 3N0QA 1NDOA 1Z03A 1WQLA 4NBDA 4NBDD 5KKZC 3GL2A 4NBFA 4P1BH 4NBFD 3GKQA 3C0DA 3CX5E 4EMJB 3VMIA 1EZVE 1SQQE 3VMID 2E4QA 1VCKA 1ZRTE 2DE6A 2DE6D 1BCCE 4U3FE 2NUKA 1RFSA 2E4PA 4PD4E 2XRXA 4AAYB 5HL4A 2YVJB 1O7NA 1KB9E 3L72E 1NTZE 2QJKC 1O7HA 1SJGA 5AEWA 5KLVE 4HM1A 2DE5D 3H1LE 3GZXA 2JO6A 3VCPA 2HMNA 2YFLA 1JM1A 3H1JE 2B1XA 4NBAA 3BCCE 3L70E 4HM8A 4HJLA 1L0LE 1ULIA 1G8KB 4HM0A 3D89A 5AEUA 1PPJE 1SQXE 4QUQA 2Q3WA 1Q90C 1Z01A 3L75E 1SQBE 4QUPA 4QDFB 1O7PA 4PV1D 2I7FA 2QJPC 2QPZA 3L74E 4NB9A 4NB9D 4QDDA 3GTSA 3GB4A 1O7MA 3GCEA 3L71E 2XR8A 4NBGA 4NBGD 1O7WA 2HMJA 4NBCD 3VMHD 3TGUE 4NBCA 1RIEA 4QURA 3VMHA 4QCKA 4HM5A 1SQVE 2HMKA 3VMGA 3VMGD 3FOUA 1UUWA 2E75D 2E74D 3GKEA 1KYOE 2CKFA 2BMOA 4OGQD 1VF5D 3GL0A 4HM4A 1NU1E 3GCFA 1SQPE 2YFIA 3VCAA 4NBAD 2IBZE
chains in the Genus database with same CATH topology
4HM6A 1NYKA 2ZT9D 2BMRA 2QJYC 3CXHE 5KLIC 4NBBA 4NBBD 2BCCE 5BOKA 2GBXA 3EN1A 1NTME 1VM9A 4H44D 4NBHA 4NBHD 1O7GA 2NVEA 2ZYLA 2HMOA 2D2CD 1G8JB 4HM7A 2FYUE 1UUVA 3GTEA 2YIUC 2HMLA 4NB8A 2B24A 4NB8D 2FYNC 1BE3E 3L73E 1Z02A 1ULJA 3GOBA 2NVGA 2XSHA 4AIVA 4NBEA 1FQTA 4NBED 4H0LD 4QDCA 1NTKE 5CXMA 3H1KE 3CWBE 1P84E 2DE7A 2A06E 2DE7D 4H13D 3GZYA 1L0NE 2NVFA 4HM3A 4HM2A 2HMMA 3H1HE 4QDFA 2XSOA 1WW9A 3DQYA 2JZAA 3AZCA 2NUMA 2GBWA 4HKVA 3H1IE 2E76D 4P1CH 2NWFA 1PP9E 2DE5A 1EG9A 2YFJA 3EQQA 2BMQA 3N0QA 1NDOA 1Z03A 1WQLA 4NBDA 4NBDD 5KKZC 3GL2A 4NBFA 4P1BH 4NBFD 3GKQA 3C0DA 3CX5E 4EMJB 3VMIA 1EZVE 1SQQE 3VMID 2E4QA 1VCKA 1ZRTE 2DE6A 2DE6D 1BCCE 4U3FE 2NUKA 1RFSA 2E4PA 4PD4E 2XRXA 4AAYB 5HL4A 2YVJB 1O7NA 1KB9E 3L72E 1NTZE 2QJKC 1O7HA 1SJGA 5AEWA 5KLVE 4HM1A 2DE5D 3H1LE 3GZXA 2JO6A 3VCPA 2HMNA 2YFLA 1JM1A 3H1JE 2B1XA 4NBAA 3BCCE 3L70E 4HM8A 4HJLA 1L0LE 1ULIA 1G8KB 4HM0A 3D89A 5AEUA 1PPJE 1SQXE 4QUQA 2Q3WA 1Q90C 1Z01A 3L75E 1SQBE 4QUPA 4QDFB 1O7PA 4PV1D 2I7FA 2QJPC 2QPZA 3L74E 4NB9A 4NB9D 4QDDA 3GTSA 3GB4A 1O7MA 3GCEA 3L71E 2XR8A 4NBGA 4NBGD 1O7WA 2HMJA 4NBCD 3VMHD 3TGUE 4NBCA 1RIEA 4QURA 3VMHA 4QCKA 4HM5A 1SQVE 2HMKA 3VMGA 3VMGD 3FOUA 1UUWA 2E75D 2E74D 3GKEA 1KYOE 2CKFA 2BMOA 4OGQD 1VF5D 3GL0A 4HM4A 1NU1E 3GCFA 1SQPE 2YFIA 3VCAA 4NBAD 2IBZE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HM6 A;  1NYK A;  2ZT9 D;  2BMR A;  2QJY C;  3CXH E;  5KLI C;  4NBB A;  4NBB D;  2BCC E;  5BOK A;  2GBX A;  3EN1 A;  1NTM E;  1VM9 A;  4H44 D;  4NBH A;  4NBH D;  1O7G A;  2NVE A;  2ZYL A;  2HMO A;  2D2C D;  1G8J B;  4HM7 A;  2FYU E;  1UUV A;  3GTE A;  2YIU C;  2HML A;  4NB8 A;  2B24 A;  4NB8 D;  2FYN C;  1BE3 E;  3L73 E;  1Z02 A;  1ULJ A;  3GOB A;  2NVG A;  2XSH A;  4AIV A;  4NBE A;  1FQT A;  4NBE D;  4H0L D;  4QDC A;  1NTK E;  5CXM A;  3H1K E;  3CWB E;  1P84 E;  2DE7 A;  2A06 E;  2DE7 D;  4H13 D;  3GZY A;  1L0N E;  2NVF A;  4HM3 A;  4HM2 A;  2HMM A;  3H1H E;  4QDF A;  2XSO A;  1WW9 A;  3DQY A;  2JZA A;  3AZC A;  2NUM A;  2GBW A;  4HKV A;  3H1I E;  2E76 D;  4P1C H;  2NWF A;  1PP9 E;  2DE5 A;  1EG9 A;  2YFJ A;  3EQQ A;  2BMQ A;  3N0Q A;  1NDO A;  1Z03 A;  1WQL A;  4NBD A;  4NBD D;  5KKZ C;  3GL2 A;  4NBF A;  4P1B H;  4NBF D;  3GKQ A;  3C0D A;  3CX5 E;  4EMJ B;  3VMI A;  1EZV E;  1SQQ E;  3VMI D;  2E4Q A;  1VCK A;  1ZRT E;  2DE6 A;  2DE6 D;  1BCC E;  4U3F E;  2NUK A;  1RFS A;  2E4P A;  4PD4 E;  2XRX A;  4AAY B;  5HL4 A;  2YVJ B;  1O7N A;  1KB9 E;  3L72 E;  1NTZ E;  2QJK C;  1O7H A;  1SJG A;  5AEW A;  5KLV E;  4HM1 A;  2DE5 D;  3H1L E;  3GZX A;  2JO6 A;  3VCP A;  2HMN A;  2YFL A;  1JM1 A;  3H1J E;  2B1X A;  4NBA A;  3BCC E;  3L70 E;  4HM8 A;  4HJL A;  1L0L E;  1ULI A;  1G8K B;  4HM0 A;  3D89 A;  5AEU A;  1PPJ E;  1SQX E;  4QUQ A;  2Q3W A;  1Q90 C;  1Z01 A;  3L75 E;  1SQB E;  4QUP A;  4QDF B;  1O7P A;  4PV1 D;  2I7F A;  2QJP C;  2QPZ A;  3L74 E;  4NB9 A;  4NB9 D;  4QDD A;  3GTS A;  3GB4 A;  1O7M A;  3GCE A;  3L71 E;  2XR8 A;  4NBG A;  4NBG D;  1O7W A;  2HMJ A;  4NBC D;  3VMH D;  3TGU E;  4NBC A;  1RIE A;  4QUR A;  3VMH A;  4QCK A;  4HM5 A;  1SQV E;  2HMK A;  3VMG A;  3VMG D;  3FOU A;  1UUW A;  2E75 D;  2E74 D;  3GKE A;  1KYO E;  2CKF A;  2BMO A;  4OGQ D;  1VF5 D;  3GL0 A;  4HM4 A;  1NU1 E;  3GCF A;  1SQP E;  2YFI A;  3VCA A;  4NBA D;  2IBZ E; 
#chains in the Genus database with same CATH topology
 4HM6 A;  1NYK A;  2ZT9 D;  2BMR A;  2QJY C;  3CXH E;  5KLI C;  4NBB A;  4NBB D;  2BCC E;  5BOK A;  2GBX A;  3EN1 A;  1NTM E;  1VM9 A;  4H44 D;  4NBH A;  4NBH D;  1O7G A;  2NVE A;  2ZYL A;  2HMO A;  2D2C D;  1G8J B;  4HM7 A;  2FYU E;  1UUV A;  3GTE A;  2YIU C;  2HML A;  4NB8 A;  2B24 A;  4NB8 D;  2FYN C;  1BE3 E;  3L73 E;  1Z02 A;  1ULJ A;  3GOB A;  2NVG A;  2XSH A;  4AIV A;  4NBE A;  1FQT A;  4NBE D;  4H0L D;  4QDC A;  1NTK E;  5CXM A;  3H1K E;  3CWB E;  1P84 E;  2DE7 A;  2A06 E;  2DE7 D;  4H13 D;  3GZY A;  1L0N E;  2NVF A;  4HM3 A;  4HM2 A;  2HMM A;  3H1H E;  4QDF A;  2XSO A;  1WW9 A;  3DQY A;  2JZA A;  3AZC A;  2NUM A;  2GBW A;  4HKV A;  3H1I E;  2E76 D;  4P1C H;  2NWF A;  1PP9 E;  2DE5 A;  1EG9 A;  2YFJ A;  3EQQ A;  2BMQ A;  3N0Q A;  1NDO A;  1Z03 A;  1WQL A;  4NBD A;  4NBD D;  5KKZ C;  3GL2 A;  4NBF A;  4P1B H;  4NBF D;  3GKQ A;  3C0D A;  3CX5 E;  4EMJ B;  3VMI A;  1EZV E;  1SQQ E;  3VMI D;  2E4Q A;  1VCK A;  1ZRT E;  2DE6 A;  2DE6 D;  1BCC E;  4U3F E;  2NUK A;  1RFS A;  2E4P A;  4PD4 E;  2XRX A;  4AAY B;  5HL4 A;  2YVJ B;  1O7N A;  1KB9 E;  3L72 E;  1NTZ E;  2QJK C;  1O7H A;  1SJG A;  5AEW A;  5KLV E;  4HM1 A;  2DE5 D;  3H1L E;  3GZX A;  2JO6 A;  3VCP A;  2HMN A;  2YFL A;  1JM1 A;  3H1J E;  2B1X A;  4NBA A;  3BCC E;  3L70 E;  4HM8 A;  4HJL A;  1L0L E;  1ULI A;  1G8K B;  4HM0 A;  3D89 A;  5AEU A;  1PPJ E;  1SQX E;  4QUQ A;  2Q3W A;  1Q90 C;  1Z01 A;  3L75 E;  1SQB E;  4QUP A;  4QDF B;  1O7P A;  4PV1 D;  2I7F A;  2QJP C;  2QPZ A;  3L74 E;  4NB9 A;  4NB9 D;  4QDD A;  3GTS A;  3GB4 A;  1O7M A;  3GCE A;  3L71 E;  2XR8 A;  4NBG A;  4NBG D;  1O7W A;  2HMJ A;  4NBC D;  3VMH D;  3TGU E;  4NBC A;  1RIE A;  4QUR A;  3VMH A;  4QCK A;  4HM5 A;  1SQV E;  2HMK A;  3VMG A;  3VMG D;  3FOU A;  1UUW A;  2E75 D;  2E74 D;  3GKE A;  1KYO E;  2CKF A;  2BMO A;  4OGQ D;  1VF5 D;  3GL0 A;  4HM4 A;  1NU1 E;  3GCF A;  1SQP E;  2YFI A;  3VCA A;  4NBA D;  2IBZ E; 
#chains in the Genus database with same CATH homology
 4HM6 A;  1NYK A;  2ZT9 D;  2BMR A;  2QJY C;  3CXH E;  5KLI C;  4NBB A;  4NBB D;  2BCC E;  5BOK A;  2GBX A;  3EN1 A;  1NTM E;  1VM9 A;  4H44 D;  4NBH A;  4NBH D;  1O7G A;  2NVE A;  2ZYL A;  2HMO A;  2D2C D;  1G8J B;  4HM7 A;  2FYU E;  1UUV A;  3GTE A;  2YIU C;  2HML A;  4NB8 A;  2B24 A;  4NB8 D;  2FYN C;  1BE3 E;  3L73 E;  1Z02 A;  1ULJ A;  3GOB A;  2NVG A;  2XSH A;  4AIV A;  4NBE A;  1FQT A;  4NBE D;  4H0L D;  4QDC A;  1NTK E;  5CXM A;  3H1K E;  3CWB E;  1P84 E;  2DE7 A;  2A06 E;  2DE7 D;  4H13 D;  3GZY A;  1L0N E;  2NVF A;  4HM3 A;  4HM2 A;  2HMM A;  3H1H E;  4QDF A;  2XSO A;  1WW9 A;  3DQY A;  2JZA A;  3AZC A;  2NUM A;  2GBW A;  4HKV A;  3H1I E;  2E76 D;  4P1C H;  2NWF A;  1PP9 E;  2DE5 A;  1EG9 A;  2YFJ A;  3EQQ A;  2BMQ A;  3N0Q A;  1NDO A;  1Z03 A;  1WQL A;  4NBD A;  4NBD D;  5KKZ C;  3GL2 A;  4NBF A;  4P1B H;  4NBF D;  3GKQ A;  3C0D A;  3CX5 E;  4EMJ B;  3VMI A;  1EZV E;  1SQQ E;  3VMI D;  2E4Q A;  1VCK A;  1ZRT E;  2DE6 A;  2DE6 D;  1BCC E;  4U3F E;  2NUK A;  1RFS A;  2E4P A;  4PD4 E;  2XRX A;  4AAY B;  5HL4 A;  2YVJ B;  1O7N A;  1KB9 E;  3L72 E;  1NTZ E;  2QJK C;  1O7H A;  1SJG A;  5AEW A;  5KLV E;  4HM1 A;  2DE5 D;  3H1L E;  3GZX A;  2JO6 A;  3VCP A;  2HMN A;  2YFL A;  1JM1 A;  3H1J E;  2B1X A;  4NBA A;  3BCC E;  3L70 E;  4HM8 A;  4HJL A;  1L0L E;  1ULI A;  1G8K B;  4HM0 A;  3D89 A;  5AEU A;  1PPJ E;  1SQX E;  4QUQ A;  2Q3W A;  1Q90 C;  1Z01 A;  3L75 E;  1SQB E;  4QUP A;  4QDF B;  1O7P A;  4PV1 D;  2I7F A;  2QJP C;  2QPZ A;  3L74 E;  4NB9 A;  4NB9 D;  4QDD A;  3GTS A;  3GB4 A;  1O7M A;  3GCE A;  3L71 E;  2XR8 A;  4NBG A;  4NBG D;  1O7W A;  2HMJ A;  4NBC D;  3VMH D;  3TGU E;  4NBC A;  1RIE A;  4QUR A;  3VMH A;  4QCK A;  4HM5 A;  1SQV E;  2HMK A;  3VMG A;  3VMG D;  3FOU A;  1UUW A;  2E75 D;  2E74 D;  3GKE A;  1KYO E;  2CKF A;  2BMO A;  4OGQ D;  1VF5 D;  3GL0 A;  4HM4 A;  1NU1 E;  3GCF A;  1SQP E;  2YFI A;  3VCA A;  4NBA D;  2IBZ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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