3VCAA

Quaternary ammonium oxidative demethylation: x-ray crystallographic, resonance raman and uv-visible spectroscopic analysis of a rieske-type demethylase
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
401
structure length
397
Chain Sequence
TSIHQRLDRRLSGFSLEQPFYTSPEVYALDLQHIFYKQWLYAVPVCQLAKAGSYTTLRVGAYEVVIVRSRDGEVRAFHNSCRHRGSLICKARQGQVAKLVCPYHQWTYELDGKLIWANDMGPDFDASKYGLKPVNLRNLDGLIYICLSDTPPDFQTFAQLARPYLEVHDLKDAKVAFTSTIIEKGNWKLVWENNRECYHCSSNHPALCRSFPLDPEVAGVGVSKKLQAHFDRCEAAGTPAQFVLAGDGQYRLARMPLQEKALSYTMDGKAAVSRHLGRVAPPDAGTLLMFHYPSTWNHFLPDHSLTFRVMPISPTETEVTTTWLVHKDAVEGVDYDLKRLTEVWIATNDEDREIVETNQQGILSPAYVPGPYSPGQESGVMQFVDWYAASLERALAP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Quaternary Ammonium Oxidative Demethylation: X-ray Crystallographic, Resonance Raman, and UV-Visible Spectroscopic Analysis of a Rieske-Type Demethylase.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Sinorhizobium meliloti
molecule keywords Ring-hydroxylating dioxygenase
total genus 124
structure length 397
sequence length 401
ec nomenclature
pdb deposition date 2012-01-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00355 Rieske Rieske [2Fe-2S] domain
A PF00848 Ring_hydroxyl_A Ring hydroxylating alpha subunit (catalytic domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domain 3vcaA02
3.90.380.10 Alpha Beta Alpha-Beta Complex Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 Naphthalene 1,2-dioxygenase Alpha Subunit; Chain A, domain 1 3vcaA01
2DE5A 3CX5E 2GBXA 1JM1A 3H1HE 1RFSA 4HM4A 2E74D 1KB9E 3N0QA 2QJYC 4PD4E 4NBBA 1Z01A 4HM2A 4QDDA 4NBFD 2NVFA 4H13D 2QPZA 2NWFA 1KYOE 4P1BH 2NVGA 2A06E 3VMID 1O7NA 4QUQA 2DE6D 3H1JE 1SQVE 1O7GA 4OGQD 1SJGA 2YFIA 1SQPE 1VF5D 4QUPA 4NBBD 1Q90C 4NBAA 2I7FA 2XSHA 5HL4A 1SQBE 4HM8A 1ULIA 1Z02A 4U3FE 4H44D 2XRXA 2GBWA 4QDFB 4NB8A 4HM7A 2DE7D 2XSOA 3GCEA 3GL0A 3EQQA 1UUWA 5KLVE 4QCKA 2JO6A 2YVJB 4NBGD 2B24A 1RIEA 2JZAA 2HMOA 2NUMA 2FYUE 2E75D 1NTME 4HM0A 2YFJA 1WQLA 4HM1A 4NB8D 2E76D 3GL2A 3AZCA 2DE5D 2Q3WA 3EN1A 2YIUC 3VCAA 1NTKE 5BOKA 2E4PA 3GCFA 4AAYB 4HM5A 4HM6A 1O7PA 5KKZC 3H1KE 3VMGA 4HKVA 1NU1E 5AEWA 2ZYLA 3VCPA 3GKQA 4NB9A 2HMJA 2IBZE 2BMOA 4NBCA 4EMJB 4QURA 3FOUA 1EG9A 2BCCE 4NBAD 1NDOA 1O7HA 2HMNA 1P84E 1SQXE 2BMRA 2HMMA 4H0LD 1VM9A 2XR8A 3GKEA 1SQQE 3GOBA 3DQYA 2BMQA 3L75E 3BCCE 3GZYA 1EZVE 4P1CH 4NBCD 3D89A 1L0LE 5CXMA 1NYKA 3L72E 1O7MA 1G8KB 2NVEA 1NTZE 2YFLA 2E4QA 3GZXA 3VMIA 2HMKA 3VMHA 4HM3A 2D2CD 3CWBE 4NBDA 2FYNC 2QJPC 4QDCA 1UUVA 3L73E 2DE6A 3TGUE 1L0NE 1FQTA 4NBHA 3C0DA 1BE3E 1O7WA 4HJLA 2NUKA 2B1XA 4AIVA 1BCCE 3GB4A 5AEUA 2CKFA 3GTEA 2HMLA 3H1LE 4NBEA 1G8JB 3L74E 2DE7A 3VMHD 3GTSA 3L71E 4NBDD 3VMGD 1VCKA 1ZRTE 1PPJE 1ULJA 4NBHD 2ZT9D 3CXHE 4NB9D 4PV1D 4NBGA 3H1IE 4QDFA 1WW9A 4NBFA 1Z03A 3L70E 4NBED 2QJKC 1PP9E 5KLIC
chains in the Genus database with same CATH superfamily
2DE5A 3CX5E 2GBXA 1JM1A 3H1HE 1RFSA 4HM4A 2E74D 1KB9E 3N0QA 2QJYC 4PD4E 4NBBA 1Z01A 4HM2A 4QDDA 4NBFD 2NVFA 4H13D 2QPZA 2NWFA 1KYOE 4P1BH 2NVGA 2A06E 3VMID 1O7NA 4QUQA 2DE6D 3H1JE 1SQVE 1O7GA 4OGQD 1SJGA 2YFIA 1SQPE 1VF5D 4QUPA 4NBBD 1Q90C 4NBAA 2I7FA 2XSHA 5HL4A 1SQBE 4HM8A 1ULIA 1Z02A 4U3FE 4H44D 2XRXA 2GBWA 4QDFB 4NB8A 4HM7A 2DE7D 2XSOA 3GCEA 3GL0A 3EQQA 1UUWA 5KLVE 4QCKA 2JO6A 2YVJB 4NBGD 2B24A 1RIEA 2JZAA 2HMOA 2NUMA 2FYUE 2E75D 1NTME 4HM0A 2YFJA 1WQLA 4HM1A 4NB8D 2E76D 3GL2A 3AZCA 2DE5D 2Q3WA 3EN1A 2YIUC 3VCAA 1NTKE 5BOKA 2E4PA 3GCFA 4AAYB 4HM5A 4HM6A 1O7PA 5KKZC 3H1KE 3VMGA 4HKVA 1NU1E 5AEWA 2ZYLA 3VCPA 3GKQA 4NB9A 2HMJA 2IBZE 2BMOA 4NBCA 4EMJB 4QURA 3FOUA 1EG9A 2BCCE 4NBAD 1NDOA 1O7HA 2HMNA 1P84E 1SQXE 2BMRA 2HMMA 4H0LD 1VM9A 2XR8A 3GKEA 1SQQE 3GOBA 3DQYA 2BMQA 3L75E 3BCCE 3GZYA 1EZVE 4P1CH 4NBCD 3D89A 1L0LE 5CXMA 1NYKA 3L72E 1O7MA 1G8KB 2NVEA 1NTZE 2YFLA 2E4QA 3GZXA 3VMIA 2HMKA 3VMHA 4HM3A 2D2CD 3CWBE 4NBDA 2FYNC 2QJPC 4QDCA 1UUVA 3L73E 2DE6A 3TGUE 1L0NE 1FQTA 4NBHA 3C0DA 1BE3E 1O7WA 4HJLA 2NUKA 2B1XA 4AIVA 1BCCE 3GB4A 5AEUA 2CKFA 3GTEA 2HMLA 3H1LE 4NBEA 1G8JB 3L74E 2DE7A 3VMHD 3GTSA 3L71E 4NBDD 3VMGD 1VCKA 1ZRTE 1PPJE 1ULJA 4NBHD 2ZT9D 3CXHE 4NB9D 4PV1D 4NBGA 3H1IE 4QDFA 1WW9A 4NBFA 1Z03A 3L70E 4NBED 2QJKC 1PP9E 5KLIC
chains in the Genus database with same CATH topology
2DE5A 3CX5E 2GBXA 1JM1A 3H1HE 1RFSA 4HM4A 2E74D 1KB9E 3N0QA 2QJYC 4PD4E 4NBBA 1Z01A 4HM2A 4QDDA 4NBFD 2NVFA 4H13D 2QPZA 2NWFA 1KYOE 4P1BH 2NVGA 2A06E 3VMID 1O7NA 4QUQA 2DE6D 3H1JE 1SQVE 1O7GA 4OGQD 1SJGA 2YFIA 1SQPE 1VF5D 4QUPA 4NBBD 1Q90C 4NBAA 2I7FA 2XSHA 5HL4A 1SQBE 4HM8A 1ULIA 1Z02A 4U3FE 4H44D 2XRXA 2GBWA 4QDFB 4NB8A 4HM7A 2DE7D 2XSOA 3GCEA 3GL0A 3EQQA 1UUWA 5KLVE 4QCKA 2JO6A 2YVJB 4NBGD 2B24A 1RIEA 2JZAA 2HMOA 2NUMA 2FYUE 2E75D 1NTME 4HM0A 2YFJA 1WQLA 4HM1A 4NB8D 2E76D 3GL2A 3AZCA 2DE5D 2Q3WA 3EN1A 2YIUC 3VCAA 1NTKE 5BOKA 2E4PA 3GCFA 4AAYB 4HM5A 4HM6A 1O7PA 5KKZC 3H1KE 3VMGA 4HKVA 1NU1E 5AEWA 2ZYLA 3VCPA 3GKQA 4NB9A 2HMJA 2IBZE 2BMOA 4NBCA 4EMJB 4QURA 3FOUA 1EG9A 2BCCE 4NBAD 1NDOA 1O7HA 2HMNA 1P84E 1SQXE 2BMRA 2HMMA 4H0LD 1VM9A 2XR8A 3GKEA 1SQQE 3GOBA 3DQYA 2BMQA 3L75E 3BCCE 3GZYA 1EZVE 4P1CH 4NBCD 3D89A 1L0LE 5CXMA 1NYKA 3L72E 1O7MA 1G8KB 2NVEA 1NTZE 2YFLA 2E4QA 3GZXA 3VMIA 2HMKA 3VMHA 4HM3A 2D2CD 3CWBE 4NBDA 2FYNC 2QJPC 4QDCA 1UUVA 3L73E 2DE6A 3TGUE 1L0NE 1FQTA 4NBHA 3C0DA 1BE3E 1O7WA 4HJLA 2NUKA 2B1XA 4AIVA 1BCCE 3GB4A 5AEUA 2CKFA 3GTEA 2HMLA 3H1LE 4NBEA 1G8JB 3L74E 2DE7A 3VMHD 3GTSA 3L71E 4NBDD 3VMGD 1VCKA 1ZRTE 1PPJE 1ULJA 4NBHD 2ZT9D 3CXHE 4NB9D 4PV1D 4NBGA 3H1IE 4QDFA 1WW9A 4NBFA 1Z03A 3L70E 4NBED 2QJKC 1PP9E 5KLIC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DE5 A;  3CX5 E;  2GBX A;  1JM1 A;  3H1H E;  1RFS A;  4HM4 A;  2E74 D;  1KB9 E;  3N0Q A;  2QJY C;  4PD4 E;  4NBB A;  1Z01 A;  4HM2 A;  4QDD A;  4NBF D;  2NVF A;  4H13 D;  2QPZ A;  2NWF A;  1KYO E;  4P1B H;  2NVG A;  2A06 E;  3VMI D;  1O7N A;  4QUQ A;  2DE6 D;  3H1J E;  1SQV E;  1O7G A;  4OGQ D;  1SJG A;  2YFI A;  1SQP E;  1VF5 D;  4QUP A;  4NBB D;  1Q90 C;  4NBA A;  2I7F A;  2XSH A;  5HL4 A;  1SQB E;  4HM8 A;  1ULI A;  1Z02 A;  4U3F E;  4H44 D;  2XRX A;  2GBW A;  4QDF B;  4NB8 A;  4HM7 A;  2DE7 D;  2XSO A;  3GCE A;  3GL0 A;  3EQQ A;  1UUW A;  5KLV E;  4QCK A;  2JO6 A;  2YVJ B;  4NBG D;  2B24 A;  1RIE A;  2JZA A;  2HMO A;  2NUM A;  2FYU E;  2E75 D;  1NTM E;  4HM0 A;  2YFJ A;  1WQL A;  4HM1 A;  4NB8 D;  2E76 D;  3GL2 A;  3AZC A;  2DE5 D;  2Q3W A;  3EN1 A;  2YIU C;  3VCA A;  1NTK E;  5BOK A;  2E4P A;  3GCF A;  4AAY B;  4HM5 A;  4HM6 A;  1O7P A;  5KKZ C;  3H1K E;  3VMG A;  4HKV A;  1NU1 E;  5AEW A;  2ZYL A;  3VCP A;  3GKQ A;  4NB9 A;  2HMJ A;  2IBZ E;  2BMO A;  4NBC A;  4EMJ B;  4QUR A;  3FOU A;  1EG9 A;  2BCC E;  4NBA D;  1NDO A;  1O7H A;  2HMN A;  1P84 E;  1SQX E;  2BMR A;  2HMM A;  4H0L D;  1VM9 A;  2XR8 A;  3GKE A;  1SQQ E;  3GOB A;  3DQY A;  2BMQ A;  3L75 E;  3BCC E;  3GZY A;  1EZV E;  4P1C H;  4NBC D;  3D89 A;  1L0L E;  5CXM A;  1NYK A;  3L72 E;  1O7M A;  1G8K B;  2NVE A;  1NTZ E;  2YFL A;  2E4Q A;  3GZX A;  3VMI A;  2HMK A;  3VMH A;  4HM3 A;  2D2C D;  3CWB E;  4NBD A;  2FYN C;  2QJP C;  4QDC A;  1UUV A;  3L73 E;  2DE6 A;  3TGU E;  1L0N E;  1FQT A;  4NBH A;  3C0D A;  1BE3 E;  1O7W A;  4HJL A;  2NUK A;  2B1X A;  4AIV A;  1BCC E;  3GB4 A;  5AEU A;  2CKF A;  3GTE A;  2HML A;  3H1L E;  4NBE A;  1G8J B;  3L74 E;  2DE7 A;  3VMH D;  3GTS A;  3L71 E;  4NBD D;  3VMG D;  1VCK A;  1ZRT E;  1PPJ E;  1ULJ A;  4NBH D;  2ZT9 D;  3CXH E;  4NB9 D;  4PV1 D;  4NBG A;  3H1I E;  4QDF A;  1WW9 A;  4NBF A;  1Z03 A;  3L70 E;  4NBE D;  2QJK C;  1PP9 E;  5KLI C; 
#chains in the Genus database with same CATH topology
 2DE5 A;  3CX5 E;  2GBX A;  1JM1 A;  3H1H E;  1RFS A;  4HM4 A;  2E74 D;  1KB9 E;  3N0Q A;  2QJY C;  4PD4 E;  4NBB A;  1Z01 A;  4HM2 A;  4QDD A;  4NBF D;  2NVF A;  4H13 D;  2QPZ A;  2NWF A;  1KYO E;  4P1B H;  2NVG A;  2A06 E;  3VMI D;  1O7N A;  4QUQ A;  2DE6 D;  3H1J E;  1SQV E;  1O7G A;  4OGQ D;  1SJG A;  2YFI A;  1SQP E;  1VF5 D;  4QUP A;  4NBB D;  1Q90 C;  4NBA A;  2I7F A;  2XSH A;  5HL4 A;  1SQB E;  4HM8 A;  1ULI A;  1Z02 A;  4U3F E;  4H44 D;  2XRX A;  2GBW A;  4QDF B;  4NB8 A;  4HM7 A;  2DE7 D;  2XSO A;  3GCE A;  3GL0 A;  3EQQ A;  1UUW A;  5KLV E;  4QCK A;  2JO6 A;  2YVJ B;  4NBG D;  2B24 A;  1RIE A;  2JZA A;  2HMO A;  2NUM A;  2FYU E;  2E75 D;  1NTM E;  4HM0 A;  2YFJ A;  1WQL A;  4HM1 A;  4NB8 D;  2E76 D;  3GL2 A;  3AZC A;  2DE5 D;  2Q3W A;  3EN1 A;  2YIU C;  3VCA A;  1NTK E;  5BOK A;  2E4P A;  3GCF A;  4AAY B;  4HM5 A;  4HM6 A;  1O7P A;  5KKZ C;  3H1K E;  3VMG A;  4HKV A;  1NU1 E;  5AEW A;  2ZYL A;  3VCP A;  3GKQ A;  4NB9 A;  2HMJ A;  2IBZ E;  2BMO A;  4NBC A;  4EMJ B;  4QUR A;  3FOU A;  1EG9 A;  2BCC E;  4NBA D;  1NDO A;  1O7H A;  2HMN A;  1P84 E;  1SQX E;  2BMR A;  2HMM A;  4H0L D;  1VM9 A;  2XR8 A;  3GKE A;  1SQQ E;  3GOB A;  3DQY A;  2BMQ A;  3L75 E;  3BCC E;  3GZY A;  1EZV E;  4P1C H;  4NBC D;  3D89 A;  1L0L E;  5CXM A;  1NYK A;  3L72 E;  1O7M A;  1G8K B;  2NVE A;  1NTZ E;  2YFL A;  2E4Q A;  3GZX A;  3VMI A;  2HMK A;  3VMH A;  4HM3 A;  2D2C D;  3CWB E;  4NBD A;  2FYN C;  2QJP C;  4QDC A;  1UUV A;  3L73 E;  2DE6 A;  3TGU E;  1L0N E;  1FQT A;  4NBH A;  3C0D A;  1BE3 E;  1O7W A;  4HJL A;  2NUK A;  2B1X A;  4AIV A;  1BCC E;  3GB4 A;  5AEU A;  2CKF A;  3GTE A;  2HML A;  3H1L E;  4NBE A;  1G8J B;  3L74 E;  2DE7 A;  3VMH D;  3GTS A;  3L71 E;  4NBD D;  3VMG D;  1VCK A;  1ZRT E;  1PPJ E;  1ULJ A;  4NBH D;  2ZT9 D;  3CXH E;  4NB9 D;  4PV1 D;  4NBG A;  3H1I E;  4QDF A;  1WW9 A;  4NBF A;  1Z03 A;  3L70 E;  4NBE D;  2QJK C;  1PP9 E;  5KLI C; 
#chains in the Genus database with same CATH homology
 2DE5 A;  3CX5 E;  2GBX A;  1JM1 A;  3H1H E;  1RFS A;  4HM4 A;  2E74 D;  1KB9 E;  3N0Q A;  2QJY C;  4PD4 E;  4NBB A;  1Z01 A;  4HM2 A;  4QDD A;  4NBF D;  2NVF A;  4H13 D;  2QPZ A;  2NWF A;  1KYO E;  4P1B H;  2NVG A;  2A06 E;  3VMI D;  1O7N A;  4QUQ A;  2DE6 D;  3H1J E;  1SQV E;  1O7G A;  4OGQ D;  1SJG A;  2YFI A;  1SQP E;  1VF5 D;  4QUP A;  4NBB D;  1Q90 C;  4NBA A;  2I7F A;  2XSH A;  5HL4 A;  1SQB E;  4HM8 A;  1ULI A;  1Z02 A;  4U3F E;  4H44 D;  2XRX A;  2GBW A;  4QDF B;  4NB8 A;  4HM7 A;  2DE7 D;  2XSO A;  3GCE A;  3GL0 A;  3EQQ A;  1UUW A;  5KLV E;  4QCK A;  2JO6 A;  2YVJ B;  4NBG D;  2B24 A;  1RIE A;  2JZA A;  2HMO A;  2NUM A;  2FYU E;  2E75 D;  1NTM E;  4HM0 A;  2YFJ A;  1WQL A;  4HM1 A;  4NB8 D;  2E76 D;  3GL2 A;  3AZC A;  2DE5 D;  2Q3W A;  3EN1 A;  2YIU C;  3VCA A;  1NTK E;  5BOK A;  2E4P A;  3GCF A;  4AAY B;  4HM5 A;  4HM6 A;  1O7P A;  5KKZ C;  3H1K E;  3VMG A;  4HKV A;  1NU1 E;  5AEW A;  2ZYL A;  3VCP A;  3GKQ A;  4NB9 A;  2HMJ A;  2IBZ E;  2BMO A;  4NBC A;  4EMJ B;  4QUR A;  3FOU A;  1EG9 A;  2BCC E;  4NBA D;  1NDO A;  1O7H A;  2HMN A;  1P84 E;  1SQX E;  2BMR A;  2HMM A;  4H0L D;  1VM9 A;  2XR8 A;  3GKE A;  1SQQ E;  3GOB A;  3DQY A;  2BMQ A;  3L75 E;  3BCC E;  3GZY A;  1EZV E;  4P1C H;  4NBC D;  3D89 A;  1L0L E;  5CXM A;  1NYK A;  3L72 E;  1O7M A;  1G8K B;  2NVE A;  1NTZ E;  2YFL A;  2E4Q A;  3GZX A;  3VMI A;  2HMK A;  3VMH A;  4HM3 A;  2D2C D;  3CWB E;  4NBD A;  2FYN C;  2QJP C;  4QDC A;  1UUV A;  3L73 E;  2DE6 A;  3TGU E;  1L0N E;  1FQT A;  4NBH A;  3C0D A;  1BE3 E;  1O7W A;  4HJL A;  2NUK A;  2B1X A;  4AIV A;  1BCC E;  3GB4 A;  5AEU A;  2CKF A;  3GTE A;  2HML A;  3H1L E;  4NBE A;  1G8J B;  3L74 E;  2DE7 A;  3VMH D;  3GTS A;  3L71 E;  4NBD D;  3VMG D;  1VCK A;  1ZRT E;  1PPJ E;  1ULJ A;  4NBH D;  2ZT9 D;  3CXH E;  4NB9 D;  4PV1 D;  4NBG A;  3H1I E;  4QDF A;  1WW9 A;  4NBF A;  1Z03 A;  3L70 E;  4NBE D;  2QJK C;  1PP9 E;  5KLI C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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